LOCUS       KCVT01000001             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8075:13906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000001
VERSION     KCVT01000001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8075:13906"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..328
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77526.1"
                     /translation="CQQHADSPRTF"
     J_segment       330..365
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           96 a          102 c           90 g           80 t
ORIGIN      
        1 acatgggggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      121 ccacgatata aataattggt tggcctggta tcaacagaaa ccaggaaaag cccctaacct
      181 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttca gtggaagtgg
      241 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt tcgcaacata
      301 ttactgtcaa cagcatgctg attcccctcg gacgttcggc caagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01000002             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10693:10454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000002
VERSION     KCVT01000002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10693:10454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77527.1"
                     /translation="CMQSLEIPPTF"
     J_segment       400..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt ggggatggaa acacctattt ggattggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agggtggagg ctgaggatgt
      361 tgggatttat tactgcatgc aatctctaga gattcctccc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000003             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15647:10361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000003
VERSION     KCVT01000003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15647:10361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77528.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000004             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:6800:3863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000004
VERSION     KCVT01000004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:6800:3863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77529.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggcccccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000005             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18678:12529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000005
VERSION     KCVT01000005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18678:12529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77530.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          126 c          123 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000006             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20797:13212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000006
VERSION     KCVT01000006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20797:13212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77531.1"
                     /translation="CLQYKNYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          114 c           96 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggttat
      181 tatcaattat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgatata
      241 tgctgcatcc agattggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa aactacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000007             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14666:4011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000007
VERSION     KCVT01000007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14666:4011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77532.1"
                     /translation="CLQYKSYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          105 a          113 c          102 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagttgactc agtctccatc
      121 ttccctgtct gcatctatag gagacactgt caccatcact tgccgggcaa gtcaggctat
      181 tagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa agttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01000008             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:24557:9108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000008
VERSION     KCVT01000008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24557:9108"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77533.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatt gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000009             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:9580:17289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000009
VERSION     KCVT01000009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9580:17289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77534.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          118 c          103 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaacccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacaa tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01000010             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12554:17607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000010
VERSION     KCVT01000010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12554:17607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77535.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           94 a          122 c          120 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttttgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gccactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatttc tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggaaatcaag cgag
//
LOCUS       KCVT01000011             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12732:12297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000011
VERSION     KCVT01000011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12732:12297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..423
                     /note="immunoglobulin light chain variable region"
     V_region        87..423
     V_segment       87..385
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77536.1"
                     /translation="CMQGTHLPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          118 c          109 g          101 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccatga ggctccctgc tcagctcctg gggctgctat
       61 tgctctgcgt ccccggatcc agtggggatg ttgtgatgac tcagtctcca ctctccctgt
      121 ctatcactct tggacaaccg gcctccattt cctgcaggtc tagtcacacc cttgtacaca
      181 gtgatgggaa aacctacttg aattggtatc agcagaagcc aggccaacct ccaaggcgcc
      241 taatttatca ggtttctaac cgggactctg gggtcccaga cagattcagc ggcagtgggg
      301 cagggacaga tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggagtttatt
      361 actgcatgca aggtacacac cttccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01000012             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20088:9712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000012
VERSION     KCVT01000012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20088:9712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77537.1"
                     /translation="CLQGYSPPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          118 c          110 g           97 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgattattta agttggtgtc agcagaaacc aggaaaaact cctgagcgcc
      241 tgatctatgc tgcatccagt ttggaaggtg gggtcccatc aagattcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaggttatt
      361 tctgtctaca gggttacagt cccccattca ctttcggccc cgggaccaaa ctggatttca
      421 aacgag
//
LOCUS       KCVT01000013             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:25642:8857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000013
VERSION     KCVT01000013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25642:8857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77538.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcccgggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000014             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22535:19143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000014
VERSION     KCVT01000014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22535:19143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77539.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggactg gtacctgcag aagccgggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000015             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15923:5696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000015
VERSION     KCVT01000015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15923:5696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77540.1"
                     /translation="CMQALEFPLTF"
     J_segment       261..297
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           69 a           69 c           89 g           73 t
ORIGIN      
        1 acatggggcc ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg
       61 gaaacaccta tttggaatgg tacctgcaga agccaggcca gtctccacag ctcttgattt
      121 atgaggtttc ctaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca
      181 ctgatttcac actgaagatc agcagagtgg aggctgagga tgttggggtt tattactgca
      241 tgcaagctct agagtttcct ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000016             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16795:19632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000016
VERSION     KCVT01000016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16795:19632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77541.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c          103 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgag gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg ataccaaacg
      421 ag
//
LOCUS       KCVT01000017             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:3611:10157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000017
VERSION     KCVT01000017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3611:10157"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77542.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaagctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000018             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17019:14273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000018
VERSION     KCVT01000018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17019:14273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77543.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01000019             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13323:18507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000019
VERSION     KCVT01000019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13323:18507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77544.1"
                     /translation="CIQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatactgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtct gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcattcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000020             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9751:6193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000020
VERSION     KCVT01000020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9751:6193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77545.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga catcaaacga g
//
LOCUS       KCVT01000021             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8371:8086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000021
VERSION     KCVT01000021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8371:8086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..387
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77546.1"
                     /translation="CMQALEFPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           90 a          113 c          122 g          102 t
ORIGIN      
        1 acatgggcag gtcaccttct cacaatgagg ctccctgctc agctcctggg actgctaatg
       61 ctctggctcc ctggatccag cggggacgta gtgatgaccc agactccact ctccctgtcc
      121 gtcacccttg gagagtcggc ctccatctcc tgcaggtcta gtcagagcct cttggatggt
      181 gaggatggaa acacctactt ggaatggtat ttgcagaagc caggccagtc tccacagctc
      241 ttgatttatg aggtttccaa gcgggcctct ggagtcccag acaggttcag tgtcagtggg
      301 tcaggcactg atttcacact gaaaatcagc agagtggagg ctggggatgt tggggtttat
      361 cactgcatgc aagctctaga gtttcctctc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01000022             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18547:10820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000022
VERSION     KCVT01000022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18547:10820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77547.1"
                     /translation="CLQYKNFPLSF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          112 c          107 g          102 t
ORIGIN      
        1 acagggggga gtcagacaca gtcaggacac agcatgggca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccaggtgtg acatccagat gactcagtct
      121 ccgtcttccc tgtctgcatc tctaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gatattaaca gttatttaaa ttggtttcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatggtg catccagttt ggaaagtgag gtcccattaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttatttc
      361 tgtctacagt ataaaaattt cccgctctct ttcggcggag ggaccagggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01000023             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:25725:10571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000023
VERSION     KCVT01000023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25725:10571"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..247
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77548.1"
                     /translation="CQQYNSLPYSF"
     J_segment       248..285
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           85 a           62 c           74 g           67 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gccgggcaag tcaggacatt agcagttttt
       61 taaattggta tcagcagaaa ccggggaaag cccctaaggt cctgatctat tatgcaaacc
      121 gtttggaaag aggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag tagcctgcaa cctgaggatt ttgcaactta ttactgtcaa cagtataata
      241 gtttaccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01000024             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:26018:20860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000024
VERSION     KCVT01000024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26018:20860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77549.1"
                     /translation="CMQVLEFPFTF"
     J_segment       275..312
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           71 a           80 c           84 g           80 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagtctc
      121 cacaactctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga gaatcagcag agtggaggct gaggatgttg
      241 gggtttattt ctgcatgcaa gttctagaat ttccattcac tttcggcccc gggaccaaag
      301 tggaaatcaa acgag
//
LOCUS       KCVT01000025             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15126:9127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000025
VERSION     KCVT01000025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15126:9127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    134..455
                     /note="immunoglobulin light chain variable region"
     V_region        134..455
     V_segment       134..413
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <395..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77550.1"
                     /translation="CQQYDSEPRTF"
     J_segment       421..455
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>458
                     /gene="IGKC"
BASE COUNT          115 a          123 c          120 g          100 t
ORIGIN      
        1 acatggggag acttattaat aggctaggca cgcttcatgc aggagtcaga cccagtcagg
       61 acacagcatg gacatgaggg tccccgctca gctcctagga ctcctgctgc tctgtctccc
      121 aggtgccaaa tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg
      181 agacagaatc accatcactt gtcgggcgag tcagggcatt cgcagttatt tagcgtggta
      241 tcagcagaaa ccagggaaag ccccgaagcc cttgatctat tacgcgtcca ctttggaaag
      301 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      361 cagcctgcag cctgaagatt ttgcaactta ttactgtcaa caatatgaca gtgagccgcg
      421 cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01000026             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6152:11457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000026
VERSION     KCVT01000026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6152:11457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77551.1"
                     /translation="CQQHNTYPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagtaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tcttttacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taatacttac ccgtacactt ttggccaggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000027             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12885:8962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000027
VERSION     KCVT01000027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12885:8962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77552.1"
                     /translation="CQQYSTLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          109 c          112 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtttccacc
      121 ctccctgtcc gcatctgaag gagacagagt caccatcact tgccgggcaa gtgagggcat
      181 tggttattat ttaaattggt atcagcagaa accggggaag gcccctaagg tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaagggtc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtatagt actttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000028             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:26878:8460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000028
VERSION     KCVT01000028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:26878:8460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77553.1"
                     /translation="CQQGYSYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          118 c          113 g           94 t
ORIGIN      
        1 acatgggggg tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 cctcctccct gtccgcatct gtgggagacg cagccacgat cacttgccag gcgagtcaag
      181 gcattggcaa taacttaaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataagac atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac ccgtggacgt tcggccaagg ggccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000029             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20377:5327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000029
VERSION     KCVT01000029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20377:5327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77554.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          125 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tgctgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac gctgatttca cactgcgaat cagcagagcg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga gatcaaacga g
//
LOCUS       KCVT01000030             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16124:7164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000030
VERSION     KCVT01000030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16124:7164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77555.1"
                     /translation="CLQSKNSPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          103 a          114 c          113 g          101 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcgtc tgcagagcca gtgagagtgt
      181 caatgtcttt ggaataaacc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 acccctgatt taccaagcat ccaataaaga aactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgatg atgctgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggacgttt ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01000031             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:8832:14882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000031
VERSION     KCVT01000031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8832:14882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77556.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000032             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:8304:3087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000032
VERSION     KCVT01000032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:8304:3087"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77557.1"
                     /translation="CQQGYNTPVTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          111 c          118 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgttggagac aaagtcacca tcacttgccg agccagtcag
      181 gatattagta gttggttagt ctggtatcag cagaaaccag ggaaagcccc taaggtcctg
      241 atctataagg cgtccagttt ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcaggctg aagattttgc aacttattat
      361 tgtcaacagg gttacaatac cccggtcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000033             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8172:6333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000033
VERSION     KCVT01000033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8172:6333"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77558.1"
                     /translation="CLQYNSSPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          117 c          110 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacatag catggacatg agggtccctg ctcagttcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgccggg cgagtcagac
      181 tattagcagc tggttagact ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctttaaggca tccagtttgc aaagtggggt cccctcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tctacagtac aatagtagcc cgctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000034             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:18077:21405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000034
VERSION     KCVT01000034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18077:21405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77559.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgagattt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcacagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000035             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25206:3948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000035
VERSION     KCVT01000035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25206:3948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77560.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atattggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01000036             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11369:16272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000036
VERSION     KCVT01000036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11369:16272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77561.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat tagcagagtg gaggctgagg
      361 atgttggggt tttttactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000037             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18851:14090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000037
VERSION     KCVT01000037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18851:14090"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77562.1"
                     /translation="CQQYNTLITF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          110 c          106 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tgggggtcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cgcttgccgg gcaagtcagg
      181 acataagtaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttatttct
      361 gtcaacagta taacacttta atcactttcg gcgggggaac caaggtggag atcaaacgag
//
LOCUS       KCVT01000038             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22662:13209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000038
VERSION     KCVT01000038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22662:13209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77563.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattctgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt ccccgacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000039             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18347:13330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000039
VERSION     KCVT01000039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18347:13330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77564.1"
                     /translation="CQQNSNRPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          122 c          119 g           88 t
ORIGIN      
        1 acatgggggg ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaattgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagtagttta gcctggtacc agcagagacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcgtccagc agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc cgaagatgtt gcagtttatt
      361 tttgtcagca gaatagtaat cggccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01000040             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:9245:12471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000040
VERSION     KCVT01000040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:9245:12471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77565.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga aggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000041             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23432:10677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000041
VERSION     KCVT01000041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23432:10677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..407
                     /note="immunoglobulin light chain variable region"
     V_region        89..407
     V_segment       89..372
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <350..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77566.1"
                     /translation="CQQVLTNPAF"
     J_segment       375..407
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>410
                     /gene="IGKC"
BASE COUNT          100 a          110 c          104 g           96 t
ORIGIN      
        1 acatggggag tcaggacaca gcatggacat gagggtccct gctcagctcc tggggctcct
       61 gctgctctgg ctcccaggtg ccagatgtga tatccaggtg acccagtctc catctgcctt
      121 gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga acatttatag
      181 gaatttagcg tggtatcagc agaaaccagg gaaagcccct aaactcctga tctatgctgc
      241 atccagattg caaagtgggt ttccctctcg gttcagcggc agtggatctg ggacagattt
      301 cactctcacc atcagcaacc tacagcctga agattctgca atttattact gtcaacaggt
      361 tcttactaac ccggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000042             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:23507:17610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000042
VERSION     KCVT01000042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23507:17610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..388
                     /note="immunoglobulin light chain variable region"
     V_region        75..388
     V_segment       75..359
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77567.1"
                     /translation="CLQYSESPLSF"
     J_segment       364..388
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>399
                     /gene="IGKC"
BASE COUNT           91 a          110 c          102 g           96 t
ORIGIN      
        1 acatgggcat ggacatgagg gtccccgctc agttcctggg gctcctgctg ctctggctcc
       61 caggtgccag atgtgacatc cagatgaccc agtctccatc ctccctgtct gcatctgtag
      121 gagacacagt caccatcact tgccgggcga gtcagactat tcgcagttgg ttaaactggt
      181 ttcaacagaa gtcaggaaaa gcccctaaac tcctgatcta tagggcgtcc attttacaaa
      241 gtggagtccc atcaaggttc agcggcagtg gatctgggac agatttcact ctcaccatca
      301 gcagcctgca acctgaagat tttgcgactt acttctgtct acagtatagt gagagccctc
      361 tctctttcgg cggggggacc aaggtggaca ttagacgag
//
LOCUS       KCVT01000043             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16644:3249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000043
VERSION     KCVT01000043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16644:3249"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77568.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000044             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14915:16779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000044
VERSION     KCVT01000044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14915:16779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..374
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77569.1"
                     /translation="CQQYYSFPITF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          100 a          113 c          115 g           98 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggatcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtgggag acaaagtcac catcacttgc cgagccagtc
      181 agggtattaa cacctggtta atttggtatc agcagaaacc agggaaagcc cctaaggccc
      241 tgatctataa ggcatccagt ttgcaaggtg gggtcccttc caggttcagc ggcagtggat
      301 ctggggcaga cttcactctc accatcacca acctgcagcc tgaagatttt ggaatttatt
      361 actgtcaaca atattatagt tttccgatca ctttcggtgg ggggaccaag gtggagatca
      421 ggcgag
//
LOCUS       KCVT01000045             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22491:4636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000045
VERSION     KCVT01000045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22491:4636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77570.1"
                     /translation="CQQYNSLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01000046             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21763:2610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000046
VERSION     KCVT01000046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21763:2610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77571.1"
                     /translation="CQQYDSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000047             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21897:12878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000047
VERSION     KCVT01000047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21897:12878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77572.1"
                     /translation="CQHSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          107 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgcg
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagtccc tgagctcctg
      241 atctatactg catcgtcttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcaccctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcata gttatgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000048             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16699:8567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000048
VERSION     KCVT01000048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16699:8567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77573.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttccctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000049             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15085:24481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000049
VERSION     KCVT01000049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15085:24481"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77574.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacaccc atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000050             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7494:13762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000050
VERSION     KCVT01000050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7494:13762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77575.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgttga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcatag
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000051             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20260:5918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000051
VERSION     KCVT01000051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20260:5918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77576.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg aggtaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000052             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19587:14308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000052
VERSION     KCVT01000052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19587:14308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77577.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          112 c          110 g           98 t
ORIGIN      
        1 acatgggggg aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000053             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12786:2282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000053
VERSION     KCVT01000053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12786:2282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..372
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77578.1"
                     /translation="CQPFKNYLSVPF"
     J_segment       380..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>415
                     /gene="IGKC"
BASE COUNT          108 a          108 c           96 g          103 t
ORIGIN      
        1 acatggggag aaccactcag gacacaggat ggacatgacg gtccccgctt atctcctggg
       61 gctccttctg ctctggctcc cagatgtgac atccagatga cccagtctcc atcttccctg
      121 tctgcatctg taggagacaa agtcaccatc acttgcaggg caagtcagga cattggtaat
      181 tatttaaatt gctgtcagca gaaaccaggg aaagctccta aggtcctgat ctatggtgta
      241 tccaatttac aaagtggggt cccatcaaca ttcagcggca gtggatctgg gacagatctt
      301 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg tcaaccgttt
      361 aaaaattacc tttcggtccc tttcggcgga gggaccaagg tagacatcaa acgag
//
LOCUS       KCVT01000054             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8632:7507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000054
VERSION     KCVT01000054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8632:7507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77579.1"
                     /translation="CQQGDSYPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          112 c          114 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgtcccagt
      121 ctccttcctc cctgtctgca tctgtgggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag agattattta aattggtatc agcagcaacc ggggaaagcc cctaaactcc
      241 tgatgtatta tgcaaacagt ctggcaagtg gagtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcagtctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gggtgacagt tatcctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000055             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14398:11193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000055
VERSION     KCVT01000055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14398:11193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77580.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgttctgg ctccctggat ctagtgggga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000056             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12712:18691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000056
VERSION     KCVT01000056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12712:18691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77581.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           94 t
ORIGIN      
        1 acatggcgga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000057             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6025:22271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000057
VERSION     KCVT01000057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6025:22271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77582.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          119 c          111 g           89 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttactact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000058             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10722:8860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000058
VERSION     KCVT01000058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10722:8860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77583.1"
                     /translation="CQQYNSLPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          112 c          107 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtgggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattgtta gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taacctcctg
      241 atctattatg caaaccgttt ggaaaatggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt acctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000059             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7656:16203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000059
VERSION     KCVT01000059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7656:16203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77584.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>442
                     /gene="IGKC"
BASE COUNT           91 a          120 c          125 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcagacg ag
//
LOCUS       KCVT01000060             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6313:7931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000060
VERSION     KCVT01000060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6313:7931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77585.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000061             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15147:6811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000061
VERSION     KCVT01000061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15147:6811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77586.1"
                     /translation="CQQYNYLPRTF"
     J_segment       384..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>422
                     /gene="IGKC"
BASE COUNT          108 a          113 c          105 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagtcaa tatttaaatt ggtatcagca gaaaccgggg aaagccccta acctcctcat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aattatttac ctcggacgtt cggccaaggg accaaggtgg aaatcagacg
      421 ag
//
LOCUS       KCVT01000062             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12479:9012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000062
VERSION     KCVT01000062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12479:9012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77587.1"
                     /translation="CQQYDSDTRTF"
     J_segment       387..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cacgcgcact ttcggtggag ggaccaaggt ggagatcaat
      421 cgag
//
LOCUS       KCVT01000063             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11005:19269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000063
VERSION     KCVT01000063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11005:19269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77588.1"
                     /translation="CQQYDSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          107 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtaattat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatggaaac cgtttgggaa gcggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcgactt atcattgtca
      361 gcagtatgat agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000064             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21866:7202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000064
VERSION     KCVT01000064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21866:7202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77589.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000065             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6786:12847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000065
VERSION     KCVT01000065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6786:12847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77590.1"
                     /translation="CQQHNVYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          120 c          107 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agagaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatgtttac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000066             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6712:8007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000066
VERSION     KCVT01000066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6712:8007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77591.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          114 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg agcctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000067             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22788:12173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000067
VERSION     KCVT01000067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22788:12173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77592.1"
                     /translation="CQHSYGAPYSF"
     J_segment       379..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          109 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgttgaatcc actttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaggat gttgcaactt attactgtca
      361 gcatagttat ggtgccccgt acagttttgg ccaggggacc aaagtggaga tcatacgag
//
LOCUS       KCVT01000068             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7174:5521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000068
VERSION     KCVT01000068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7174:5521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77593.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          100 a          116 c          116 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcaacag aaaccaggac aacctcctaa
      241 actcctgatt taccaagcaa tcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaacctgacg atggtgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01000069             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23408:16722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000069
VERSION     KCVT01000069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23408:16722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77594.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000070             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:9191:10846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000070
VERSION     KCVT01000070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9191:10846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77595.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggtt ttattactgc atgcaagctc tagactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000071             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12741:7899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000071
VERSION     KCVT01000071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12741:7899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77596.1"
                     /translation="CQQYNTDPPTF"
     J_segment       382..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          125 c          102 g           89 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ccccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagcagtcat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcatcc attttggaaa gtggggtccc atcaaggttc cgcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac actgaccctc ccactttcgg ccccgggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01000072             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14198:5805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000072
VERSION     KCVT01000072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14198:5805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77597.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact tttgaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000073             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14608:14881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000073
VERSION     KCVT01000073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14608:14881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77598.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctcatgctc tggctccctg tatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cggtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 atgatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000074             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9314:8496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000074
VERSION     KCVT01000074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9314:8496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77599.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag atgccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01000075             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14690:5660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000075
VERSION     KCVT01000075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14690:5660"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77600.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggcttccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000076             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13645:10178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000076
VERSION     KCVT01000076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13645:10178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77601.1"
                     /translation="CQQYNSLPYSF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          114 a          110 c          105 g          101 t
ORIGIN      
        1 acatggggat gcaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctgg ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc
      121 cagtctccat cctccctgtc tgcctctgta ggagacaaag tcaccatcac ttgccgggca
      181 agtcaggaca ttagcagtta tttaaattgg tatcagcaga aaccggggaa agcccctaaa
      241 ctcctgatct attatacaaa ccgtttggaa agtggagtcc catcaaggtt cagcggcagt
      301 ggatctggga cagaattcac tctcaccatc agtagtctgc aatctgagga tttttcaact
      361 tattactgtc aacagtataa cagtttaccg tacagttttg gccaggggac caaagtggat
      421 atcaaacgag
//
LOCUS       KCVT01000077             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14167:18431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000077
VERSION     KCVT01000077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14167:18431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..232
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77602.1"
                     /translation="CQQGYSYPYSF"
     J_segment       238..275
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           72 a           70 c           70 g           66 t
ORIGIN      
        1 acatggggtc accatcactt gccaggcgag tcaaggcatt ggcaatactt taaattggta
       61 tcaacagaaa ccggggaaag cccctacact cctgatctat agggcatccg gtttgcaaag
      121 tgggactccc tctcggttca gcggcagtgg atctgggacg gatttcactc tcaccatcag
      181 cagcctgcag cctgaagatt ttgccactta ttactgtcaa cagggttata gttatccgta
      241 cagttttggc caggggacca aactggagat caaacgag
//
LOCUS       KCVT01000078             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:15071:15197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000078
VERSION     KCVT01000078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15071:15197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    169..323
                     /note="immunoglobulin light chain variable region"
     V_region        169..323
     V_segment       169..282
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <265..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77603.1"
                     /translation="CQQSYRYPLTF"
     J_segment       288..323
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>328
                     /gene="IGKC"
BASE COUNT           71 a           94 c           90 g           73 t
ORIGIN      
        1 acatgggggc agtctcagtc aggacacagc atggacatga gggcctctgc tcagctccta
       61 gggctcctgc tgctctggct cccaggcgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcaggag tggggtccca
      181 tcaaggttca gcggcagtgg atctgggaca gatttcactc tcgccatcag cagcctgcag
      241 cctgaagatg ctgcaactta ttactgtcag cagagttatc gttatccgct cactttcggt
      301 ggagggaccc aggtggaaat caatcgag
//
LOCUS       KCVT01000079             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21741:15482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000079
VERSION     KCVT01000079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21741:15482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77604.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          119 c          124 g          103 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca ccctgggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggcacctgc agaggccagg
      241 ccagtctcca cagctcttga tttatgaagt ttcctatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttc ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000080             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11444:16049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000080
VERSION     KCVT01000080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11444:16049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77605.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcgtcccaga caggttcagt gtcagtgggt
      301 ctggaacaga atttactctc accatcacca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000081             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:27097:9436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000081
VERSION     KCVT01000081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:27097:9436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77606.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ccaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000082             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:13311:20494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000082
VERSION     KCVT01000082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13311:20494"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77607.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cagcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000083             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12986:6085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000083
VERSION     KCVT01000083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12986:6085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77608.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggcgagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000084             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24507:16749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000084
VERSION     KCVT01000084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24507:16749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77609.1"
                     /translation="FMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattacttc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000085             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20431:6426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000085
VERSION     KCVT01000085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20431:6426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77610.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          124 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtaccagcag aggccaggcc
      241 agtctccaca gcccttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000086             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17164:20016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000086
VERSION     KCVT01000086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17164:20016"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77611.1"
                     /translation="CQQYNSFPFTF"
     J_segment       381..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT          101 a          112 c          109 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgttg gagacagagt caccatcact tgccgggcga gtcaggacat
      181 tagcagtttt ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatctt
      241 ttatgcaaat cgtttggaaa gaggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt atcactgcca
      361 acagtataat agtttccctt tcacattcgg cggagggacc aaggtggaga tcggacgag
//
LOCUS       KCVT01000087             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22340:6608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000087
VERSION     KCVT01000087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22340:6608"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77612.1"
                     /translation="CQQFSTYPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          118 c          112 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggatcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acaaagtcac catcacttgc cgagccagtc
      181 agggtattag cagctggtta gcctggtatc agcagaaacc agggaaagcc cctaagcccc
      241 tgatctataa ggcatccagt ttgcaaagtg gggtcccttc acggttcagc ggcagtggat
      301 ctgggacgga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtttagtact taccctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000088             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8776:17415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000088
VERSION     KCVT01000088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8776:17415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77613.1"
                     /translation="CQQYTSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          123 c          104 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 acgttagcac tcatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tccaacctga ggactttgca acttatcact
      361 gtcaacagta cactagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000089             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20704:16247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000089
VERSION     KCVT01000089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20704:16247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77614.1"
                     /translation="CQQYNSDPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          114 c          107 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcag cagaaaccag gaaaagcccc gaaggccttg
      241 atctattacg catccatttt agaaagtgcg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg acgattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000090             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12742:12688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000090
VERSION     KCVT01000090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12742:12688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77615.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000091             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15076:6816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000091
VERSION     KCVT01000091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15076:6816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77616.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          125 c          111 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca acagcttagc ctggtaccaa caaaaacctg ggcagcctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagagg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000092             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:4725:15806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000092
VERSION     KCVT01000092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4725:15806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77617.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          123 c          121 g           89 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct catcatcagt agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000093             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:25751:6364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000093
VERSION     KCVT01000093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25751:6364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77618.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          124 c          112 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc aaaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtgcc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000094             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14470:19579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000094
VERSION     KCVT01000094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14470:19579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77619.1"
                     /translation="CQQYNRFPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          112 c          106 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagtag ttacttaaat tggtatcagc aaaagccggg gaaagcccca aagcccctga
      241 tctattatgc aaaccgtttg gaaaatggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca atttattact
      361 gtcaacaata taataggttt cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000095             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23975:11860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000095
VERSION     KCVT01000095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23975:11860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77620.1"
                     /translation="CQHSYGTPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          113 c          106 g           97 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtaggaca agtcagaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agcccctagg ctcctgatct
      241 atgctgcgtc caatttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tttcaccatc accagcctgc aacctgaaga tgttgcaact tattactgtc
      361 agcatagtta tggtaccccg ttcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000096             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18593:14603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000096
VERSION     KCVT01000096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18593:14603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77621.1"
                     /translation="CMQGLEFPPTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggcga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggtgat ggaaacacct atttggaatg gttcctccag aggccaggcc
      241 agtctccaca cctcttgatt tatggggctt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tccgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000097             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:15059:5455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000097
VERSION     KCVT01000097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15059:5455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..330
                     /note="immunoglobulin light chain variable region"
     V_region        50..330
     V_segment       50..290
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <267..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77622.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       298..330
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>333
                     /gene="IGKC"
BASE COUNT           85 a           81 c           82 g           85 t
ORIGIN      
        1 acatgggggt ccccgcttat ctcctggggc tccttctgct ctggctccca ggagacaaag
       61 tcaccatcac ttgcagggca agtcaggaca ttggtaatta tttaaattgg tatcagcaga
      121 aaccaggaaa agctcctaag gtcctgatct atggtgtatc caatttacaa agtggggtcc
      181 catcaaggtt cagcggcagt ggatctggga cagatcttac tctcaccatc agcagcctgc
      241 agcctgaaga ttttgcaact tattattgtc aaccgtttaa aagttacctt tcggtccctt
      301 tcggcggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000098             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20028:8160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000098
VERSION     KCVT01000098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20028:8160"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..399
                     /note="immunoglobulin light chain variable region"
     V_region        80..399
     V_segment       80..352
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77623.1"
                     /translation="CQQHNGYPPTF"
     J_segment       365..399
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>402
                     /gene="IGKC"
BASE COUNT           99 a          112 c          103 g           88 t
ORIGIN      
        1 acatggggag catggacatg agggtccccg ctcagctcct ggggctcctg ctgctctggc
       61 tcccaggtgc cagatgtggc atccagatga cccagtctcc atcctccctg tctgcatctg
      121 taggagacac agtcaccatc acttgtcggg caagtcaggg cattacgaat gatttagcct
      181 ggtatcaaca gaaaccaggt aaagtcccga agcccctgat ctattacgca tccaatttgg
      241 aaagtggggt cccatcaagg ttcagcggca gcggatctgg gacagatttc actctcacca
      301 tcagcagcct gcagcctgaa gattttgcaa cttattattg tcaacagcat aatggatacc
      361 ctccgacgtt cggccaaggg accagggtgg aaatcaaacg ag
//
LOCUS       KCVT01000099             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12761:18841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000099
VERSION     KCVT01000099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12761:18841"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77624.1"
                     /translation="CLQFKTYPNSF"
     J_segment       380..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           96 a          117 c          103 g          102 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatctctt gccgggcaag tcagggtatt
      181 agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctcagct cctcatctat
      241 gctgcatcca gtttggccgg tggggtccca tcaaggttca gcggcagtgg atctggtaca
      301 gaattctctc tcaccatcac cagcctgcag cctgaagatt ttgcaactta tttctgtctg
      361 cagtttaaaa cttacccgaa cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01000100             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:25954:7560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000100
VERSION     KCVT01000100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25954:7560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77625.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaatc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000101             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24998:7670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000101
VERSION     KCVT01000101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24998:7670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77626.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agagatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggac aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcaccccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagta gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01000102             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18432:3603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000102
VERSION     KCVT01000102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18432:3603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77627.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000103             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16103:5902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000103
VERSION     KCVT01000103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16103:5902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77628.1"
                     /translation="CQQGYNTPWTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           90 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 gtattagcag ctggttagcc tggtatcaga tgaaaccagg gaaagcccct aaactcctga
      241 tctataaggc gtccagtttg gcaagtgggg tcccatcaag gttcagcggc ggtacatctg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacaggg ttacaatacc ccgtggacat tcggccaagg gaccaaggtg gaaatcaagc
      421 gag
//
LOCUS       KCVT01000104             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22582:16243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000104
VERSION     KCVT01000104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22582:16243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77629.1"
                     /translation="CIQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtct gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcattcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000105             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20511:5769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000105
VERSION     KCVT01000105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20511:5769"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77630.1"
                     /translation="CLQGYDTPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          114 c          110 g           98 t
ORIGIN      
        1 acatgggggt cagacccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctttggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tatttaagtt ggtatcagca gaagccagga aaagctccta accgcctgat
      241 ctatgctgca tccagtttgg gaagtggggt cccatctagg ttcagcggca gtggatctgc
      301 gacagaattc actctcacca tcagcagcct acagcctgaa gattttgcag cttattactg
      361 tcttcagggt tatgataccc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000106             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16724:4870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000106
VERSION     KCVT01000106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16724:4870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77631.1"
                     /translation="CQQYNSLPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          109 c          111 g           99 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgccggg caagtcaggg
      181 cattagcgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctgat
      241 ctattatgca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgtag gttattactg
      361 tcaacagtat aatagtttac cgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000107             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6645:7729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000107
VERSION     KCVT01000107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6645:7729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77632.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca ggtcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cacttaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000108             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20650:12236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000108
VERSION     KCVT01000108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20650:12236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77633.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          112 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacta tcacttgtcg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcaa ctgagaccag ggaaagcccc gaaggcctta
      241 atctattacg cgaccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aggattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000109             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13604:10129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000109
VERSION     KCVT01000109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13604:10129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..442
                     /note="immunoglobulin light chain variable region"
     V_region        121..442
     V_segment       121..390
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77634.1"
                     /translation="CLQGDTAPFTF"
     J_segment       407..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          109 a          119 c          120 g           97 t
ORIGIN      
        1 acatgggatc aacgcagagt acatgggggg agtcagaacc actcaggaca cagcatggac
       61 atgagggtcc ccgctcagct cctggggctc cttctgctct ggctcccagg tgccagatgt
      121 gacatccaga tgacccagtc tccatcttcc ctgtctgcat cggcaggaga cagagtcacc
      181 atcacttgcc gggcaagtca gggcattaac gattatttaa gttggtatca gcagaaacca
      241 ggaaaacctc ctaagcgcct gatttatgct gcatccagtt tggaaagtgg ggtcccatca
      301 aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag cctgcagcct
      361 gaagattttg cagcttatta ctgtctacag ggtgatactg ccccgttcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000110             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18094:22844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000110
VERSION     KCVT01000110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18094:22844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77635.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          119 c          114 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttattctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01000111             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11204:10283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000111
VERSION     KCVT01000111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11204:10283"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77636.1"
                     /translation="CQHSYGTPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          106 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtagg acaagtcaga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aggctcctga
      241 tctatgctgc gtccaatttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactttcacc atcaccagcc tgcaacctga agatgttgca acttattact
      361 gtcagcatag ttatggtacc ccgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000112             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18732:18948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000112
VERSION     KCVT01000112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18732:18948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77637.1"
                     /translation="CQQGNSIPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          106 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcagcat tacttgccgg gcaagtcagg
      181 gcattactaa ttatttaaat tggtatcagc agaaaccggg gaaagcccca aaggtcctga
      241 tctattatgc agacagtttg tcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtatt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000113             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7939:9828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000113
VERSION     KCVT01000113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7939:9828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77638.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          113 c          112 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccggtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000114             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5947:18151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000114
VERSION     KCVT01000114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5947:18151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77639.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcggagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000115             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23793:5885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000115
VERSION     KCVT01000115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23793:5885"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77640.1"
                     /translation="CQQHESYPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          124 c          104 g           89 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 cgacattagc gattctttag cctggtatca gcacaaacca ggaaaagccc cgaagcccct
      241 gatctattac gcatccaatt tgaaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacctatta
      361 ctgtcaacag catgaatctt acccgctcac tttcggcgga aggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000116             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22318:3621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000116
VERSION     KCVT01000116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22318:3621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..421
                     /note="immunoglobulin light chain variable region"
     V_region        94..421
     V_segment       94..377
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77641.1"
                     /translation="CQQRNSYPYMFSF"
     J_segment       387..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          113 c          108 g          102 t
ORIGIN      
        1 acatgggaga cccagtctgg acgcagcatg gacatcaggg tcctcgctca gcttctcggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agttgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcaag tcaggacatt
      181 ggtagttttt tagcctggta tcaacagaaa ccagggaaag cccctgacct cctgatctat
      241 aaggcgtcca gtttgcaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcagttta ttactgtcaa
      361 caacgtaata gttacccgta catgttcagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000117             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20811:14424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000117
VERSION     KCVT01000117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20811:14424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77642.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          126 c          116 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01000118             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21366:13051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000118
VERSION     KCVT01000118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21366:13051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77643.1"
                     /translation="CMQTLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000119             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14432:5249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000119
VERSION     KCVT01000119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14432:5249"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77644.1"
                     /translation="CQQHDNSPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          119 c          110 g           88 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctctc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggtg
      181 ttagcgactg gttggcctgg tatcaacaga gaccagggaa agcccctaaa ctcctgatct
      241 atagggcgtc caatttggat acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgctaca tattactgtc
      361 aacagcatga taattcccct ccgacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000120             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13056:14309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000120
VERSION     KCVT01000120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13056:14309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..356
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77645.1"
                     /translation="CQQHDDSPRTF"
     J_segment       358..393
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT          104 a          111 c           97 g           84 t
ORIGIN      
        1 acatggggga cacgagggtc cccgctcagc tcctggggct cctgttgctc tggctcccag
       61 gtgccagatg tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag
      121 acagagtcac catcacttgc agagccagtc acgatattaa caactggttg gcctggtatc
      181 aacagaaacc agggaaagcc cctaaggtcc tgatctatag ggcatccaat ttggaaacag
      241 gggtcccatc aaggttcagt ggaagtggtt ctgggacaga tttcactctc accatcaaca
      301 acctgcagcc tgaagatatc gcaacatatt actgtcaaca acatgatgat tcccctcgga
      361 ccttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01000121             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15503:9648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000121
VERSION     KCVT01000121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15503:9648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77646.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          112 g           95 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccat gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcatcagcaa ttatttaaat tggtatcagc agatgccggg gaaagcccct aaggtcctga
      241 tctattatac aaatcgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000122             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12860:18151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000122
VERSION     KCVT01000122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12860:18151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77647.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          125 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcgtggc tagtgaggat ggaaacacgt atttagaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 cgaaggtgga gatcaaacga g
//
LOCUS       KCVT01000123             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18637:15960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000123
VERSION     KCVT01000123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18637:15960"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77648.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          118 c          112 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagccag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000124             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25273:3538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000124
VERSION     KCVT01000124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25273:3538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77649.1"
                     /translation="CMQALEFPLTF"
     J_segment       322..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           85 a           93 c          101 g           83 t
ORIGIN      
        1 acatggggga tccagtgggg acattctgat gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcctgg atagtgaaga
      121 tggaaacacc tatttgcact ggtacctgaa gaagccaggc cagtctccac agctcttaat
      181 ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct ctagagtttc cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      361 ag
//
LOCUS       KCVT01000125             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18414:6087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000125
VERSION     KCVT01000125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18414:6087"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77650.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01000126             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12627:13173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000126
VERSION     KCVT01000126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12627:13173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77651.1"
                     /translation="CQQYITSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           95 a          130 c          108 g           93 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttatc ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctct
      241 tcatctatgg tgcatccagc agggccactg gcatccccga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtatattacc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01000127             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13877:10907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000127
VERSION     KCVT01000127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13877:10907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77652.1"
                     /translation="CQQYNSDPYTF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          107 a          113 c          115 g           95 t
ORIGIN      
        1 acatggggat gcaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctag gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccaggtgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg
      181 agtcagggca ttagaagtta tttagcgtgg tatcaggtga gaccagggaa agccccgaag
      241 gccttaatct attacgcgac cattttggaa agtggggtcc catcaaggtt cagcggcagt
      301 ggatctggga cagaattcac tctcaccatc agcagcctgc agcctgagga ttttgcaact
      361 tatttctgtc aacagtataa cagtgacccg tacacttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01000128             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22316:7821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000128
VERSION     KCVT01000128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22316:7821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77653.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaagttgga gatcaaacga g
//
LOCUS       KCVT01000129             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7459:14270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000129
VERSION     KCVT01000129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7459:14270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77654.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01000130             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15211:9155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000130
VERSION     KCVT01000130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15211:9155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77655.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          126 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 tttgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000131             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19165:20238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000131
VERSION     KCVT01000131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19165:20238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77656.1"
                     /translation="CQQHDNSPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          119 c          112 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctctctgca tctgtaggag acagagtcac catgacttgc agagccagtc
      181 agggtattaa cgactggttg gcctggtatc aacagagacc agggaaagcc cctaaactcc
      241 tgatctatag ggcgtccaat ttggatacag gggtcccatc caggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgataat tcccctccga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000132             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20454:8805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000132
VERSION     KCVT01000132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20454:8805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77657.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          124 c          113 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000133             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14429:13098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000133
VERSION     KCVT01000133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14429:13098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..241
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77658.1"
                     /translation="CQQYNSLPYSF"
     J_segment       242..279
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>282
                     /gene="IGKC"
BASE COUNT           83 a           63 c           70 g           66 t
ORIGIN      
        1 acatgggcag agtcaccatc acttgccggg caagtcagga cattagcagt tttttaaatt
       61 ggtatcagca gaaaccgggg aaagccccta aggccctgat ctattatgca aaccggttgg
      121 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca
      181 tcagcagcct gcaatctgaa gattttgcaa cttattactg tcaacagtat aatagtttac
      241 cgtacagttt tggccagggg accaaagtag agatcaaacg ag
//
LOCUS       KCVT01000134             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12535:4948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000134
VERSION     KCVT01000134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12535:4948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77659.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tggtgaagat ggaaacacct atttgcactg gtacctgaag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000135             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22902:18675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000135
VERSION     KCVT01000135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22902:18675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77660.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtggg gatcaaacga g
//
LOCUS       KCVT01000136             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13923:6780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000136
VERSION     KCVT01000136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13923:6780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77661.1"
                     /translation="CLQYKSYPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          114 c          100 g          103 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ttgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 ggttattatc aattatttaa attggtttca gcagaaacca gggaaagccc ctaagctcct
      241 gatttatgct gcatccagat tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tataaaagtt acccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01000137             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25515:15397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000137
VERSION     KCVT01000137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25515:15397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77662.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          105 c          110 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgacgc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatgact tgccgggcaa gtcaggacat
      181 tagtagttat ttaaattggt atcagcagaa accggggaaa gcccctaaat tcttgatcta
      241 ttttggaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgga acctgaagat tttgcaactt attactgtca
      361 acaatataat agtttaccgc tcaccttcgg cggagggacc gaggtggaga tcaaacgag
//
LOCUS       KCVT01000138             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13913:18021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000138
VERSION     KCVT01000138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13913:18021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77663.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000139             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15168:8412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000139
VERSION     KCVT01000139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15168:8412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77664.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          120 c          117 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 attctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc caggcaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg agactgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01000140             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:20683:13783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000140
VERSION     KCVT01000140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20683:13783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77665.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca agtcttgatt tatgaggttt ccaaccgggc ctctggagcc ccagacaggt
      301 tcagcggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000141             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10654:19183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000141
VERSION     KCVT01000141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10654:19183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..358
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77666.1"
                     /translation="SMHDSGGPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           96 a          114 c          119 g           92 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtctccatct cctgccaagc cagagcagat
      181 gtacatggtg aaatgtcttg gatccggata aaccttgaac aaagacttga acccctttta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagcccggt tcatcagcaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 atgcatgact ctggggggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 a
//
LOCUS       KCVT01000142             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24542:5272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000142
VERSION     KCVT01000142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24542:5272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..278
                     /note="immunoglobulin light chain variable region"
     V_region        75..278
     V_segment       75..241
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77667.1"
                     /translation="CQQNSNWPLTF"
     J_segment       242..278
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>281
                     /gene="IGKC"
BASE COUNT           66 a           77 c           77 g           61 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag actcctcatc tatggtgcat ccaacagggc
      121 cactggcatc ccagacaggt tcagtggcag tgggtctggg acagagttca ctctcaccat
      181 cagcagcctg gagcctgaag atgttgcact ttattattgt cagcagaata gtaactggcc
      241 tctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000143             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10460:18040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000143
VERSION     KCVT01000143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10460:18040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77668.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          116 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01000144             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13906:7647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000144
VERSION     KCVT01000144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13906:7647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..364
                     /note="immunoglobulin light chain variable region"
     V_region        43..364
     V_segment       43..327
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77669.1"
                     /translation="CQQHADSPRTF"
     J_segment       329..364
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           96 a          102 c           89 g           80 t
ORIGIN      
        1 acatgggggc tcctgttgct ctggctccca ggtgccagat gtgacatcca gatgacccag
       61 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg cacagccagc
      121 cacgatataa ataattggtt ggcctggtat caacagaaac caggaaaagc ccctaacctc
      181 ctgatctata gggcatccaa tttggaaaca ggggtcccat cgaggttcag tggaagtgga
      241 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt cgcaacatat
      301 tactgtcaac agcatgctga ttcccctcgg acgttcggcc aagggaccaa ggtggagatc
      361 aaacgag
//
LOCUS       KCVT01000145             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24018:14887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000145
VERSION     KCVT01000145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24018:14887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77670.1"
                     /translation="CQQHNGYLPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          116 c          109 g           92 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caagttatta
      361 ttgtcaacag cataatggat atcttccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000146             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22886:10064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000146
VERSION     KCVT01000146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22886:10064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77671.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagacacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcggtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000147             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24434:11838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000147
VERSION     KCVT01000147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24434:11838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..429
                     /note="immunoglobulin light chain variable region"
     V_region        108..429
     V_segment       108..390
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77672.1"
                     /translation="CQQYDSDLFTF"
     J_segment       394..429
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          105 a          116 c          114 g           97 t
ORIGIN      
        1 acatggggtc atgcaggagt cagacccagt caggacacag catggacatg agggtccccg
       61 ctcagctcct aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga
      121 cccagtctcc atcctccctg tctgcatttg taggagacag agtcaccatc acttgtcggg
      181 cgagtcaggg cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga
      241 agcccttgat ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca
      301 gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa
      361 cttattactg tcaacagtat gacagtgacc tgttcacttt cggtggaggg accaaggtgg
      421 agatcaaacg ag
//
LOCUS       KCVT01000148             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21880:10112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000148
VERSION     KCVT01000148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21880:10112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77673.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          118 c          108 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagtct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000149             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10519:6131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000149
VERSION     KCVT01000149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10519:6131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77674.1"
                     /translation="CQQHDDSPRTF"
     J_segment       391..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          112 a          117 c          111 g           89 t
ORIGIN      
        1 acatgggggg caggagtcag tctcagacag gacacagcat ggacacgagg gtccccgctc
       61 agctcctggg gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc
      121 agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca
      181 gtcaggatat taataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac
      241 tcctgatcta tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg
      301 gatctgggac agatttcact ctcaccatta gcagcctgca gcctgaagat atcgcaacat
      361 attactgtca acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01000150             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:27199:13159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000150
VERSION     KCVT01000150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:27199:13159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77675.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          123 c          120 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcaa ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000151             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17272:12347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000151
VERSION     KCVT01000151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17272:12347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77676.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000152             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20364:17112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000152
VERSION     KCVT01000152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20364:17112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..409
                     /note="immunoglobulin light chain variable region"
     V_region        126..409
     V_segment       126..371
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77677.1"
                     /translation="CMQALEFPWTF"
     J_segment       372..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           94 a          105 c          114 g           99 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctcca tctcctgcag gtctagtcag agcctcttgg atagtgaaga tggaaacacc
      181 tatttggatt ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt
      241 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      301 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      361 ctggagtttc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000153             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14613:10019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000153
VERSION     KCVT01000153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14613:10019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77678.1"
                     /translation="CLQFKTYPNSF"
     J_segment       386..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           97 a          118 c          107 g          102 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tctcttgccg ggcaagtcag
      181 ggtattagca gttctttaag ttggtttcag cagaaaccag ggaaagcccc tcagctcctc
      241 atctatgctg catccagttt ggccggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tctctctcac catcaccagc ctgcagcctg aagattttgc aacttatttc
      361 tgtctgcagt ttaaaactta cccgaacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000154             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25172:12824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000154
VERSION     KCVT01000154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25172:12824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77679.1"
                     /translation="CMQSLEIPPTF"
     J_segment       400..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt ggggatggaa acacctattt ggattggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tgggatttat tactgcatgc aatctctaga gattcctccc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000155             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13138:18126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000155
VERSION     KCVT01000155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13138:18126"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77680.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgatagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000156             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14954:8166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000156
VERSION     KCVT01000156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14954:8166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77681.1"
                     /translation="CQQYDSDPYSF"
     J_segment       385..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          114 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattagg agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac acatccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgtacag ttttggccag gggaccagag tggagatcca
      421 acgag
//
LOCUS       KCVT01000157             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10512:6905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000157
VERSION     KCVT01000157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10512:6905"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77682.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatt acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tcgagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000158             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:20753:8859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000158
VERSION     KCVT01000158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20753:8859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77683.1"
                     /translation="CMQALEFPLTF"
     J_segment       408..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           99 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gagacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg taggtctagt
      181 cagagcctct tggatagtga ggatggaaat acctatttgg aatggcaccg gcagatgcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctgac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000159             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8525:8069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000159
VERSION     KCVT01000159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8525:8069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..410
                     /note="immunoglobulin light chain variable region"
     V_region        86..410
     V_segment       86..372
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77684.1"
                     /translation="CQQGNSIPLTF"
     J_segment       373..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          105 a          111 c          103 g           94 t
ORIGIN      
        1 acatggggag ggctcagcta acataatgga ttttcaggct caaattttca tcttccttct
       61 gctcagtgtc acagtgtcca atggagaaat tgtgctgacc cagtctccaa catccatggc
      121 tgtctcccaa ggagaaagag tcaccatctc ctgcacggcc agttcaagtg taagcaccag
      181 ctacctgcac tggtaccaac agaagccagg attccctcca aggcttcttg tccatagaac
      241 atcaagtctg gcttctgggg tcccagccag gttcagtggc agcggttctg ggacctctta
      301 cacgctcaca atcagcagca tggaggctga agatgctgca aactattact gtcagcaggg
      361 gaatagcatt ccgctcactt tcggcggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000160             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4695:11601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000160
VERSION     KCVT01000160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4695:11601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77685.1"
                     /translation="CQQYESDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          113 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagtagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgaaagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000161             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:21482:17946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000161
VERSION     KCVT01000161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21482:17946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77686.1"
                     /translation="CQQYNSLPLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          107 c          110 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc agctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcatctct gggggacaga gtcaccatca cttgccgggc aagtcaggac
      181 attagcagat atttaaattg gtatcagcag aaaccgggga aagcccctaa gttcctgatc
      241 tattatgtaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattattgt
      361 caacagtata atagtttacc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000162             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23627:7447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000162
VERSION     KCVT01000162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23627:7447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77687.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaagcagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01000163             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16586:5442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000163
VERSION     KCVT01000163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16586:5442"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77688.1"
                     /translation="CQQYDSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgtatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcaa ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatgc aaaccgtttg gaaagagggg tcccatcaag gttcaccggc agtggatctg
      301 ggacagagtt cactctcacc atcagtagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta tgatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000164             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21544:12354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000164
VERSION     KCVT01000164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21544:12354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77689.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          118 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acgcagactc
      121 cattctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc tcagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggttga gatcaaacga g
//
LOCUS       KCVT01000165             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18891:17729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000165
VERSION     KCVT01000165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18891:17729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77690.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta acctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000166             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17475:5265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000166
VERSION     KCVT01000166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17475:5265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77691.1"
                     /translation="CQQGNSNPLTF"
     J_segment       379..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          106 a          110 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtttccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggccat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatata
      241 ctatggaaaa gtttggcaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcac cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagggtaata gtaatcctct cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01000167             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21025:16333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000167
VERSION     KCVT01000167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21025:16333"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77692.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          118 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcggtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000168             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8153:12824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000168
VERSION     KCVT01000168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8153:12824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77693.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 aatctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000169             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:23645:6130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000169
VERSION     KCVT01000169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23645:6130"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..347
                     /note="immunoglobulin light chain variable region"
     V_region        8..347
     V_segment       8..309
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <287..>319
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77694.1"
                     /translation="CMQALEFPWTF"
     J_segment       310..347
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>350
                     /gene="IGKC"
BASE COUNT           81 a           90 c          101 g           78 t
ORIGIN      
        1 acatggggac attgtgatga cccagactcc actctccctg cccgtcaccc ctggagagcc
       61 ggcctccgtc tcctgcaggt ctagtcagag cctcttggat agtgaggatg gaaacaccta
      121 tctggattgg tacctgcaga agccaggcca gtctccacag ctcttgattt atgaggtttc
      181 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgacttcac
      241 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgta tgcaagcact
      301 ggagtttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000170             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11967:15892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000170
VERSION     KCVT01000170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11967:15892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77695.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          116 c          106 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcaggatat
      181 taacacctgg ttggcctggt atcaacagaa gccagggaaa gcccctaagg tcctgatcta
      241 taggacatcc aatttggaaa caagggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca acagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000171             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18878:13908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000171
VERSION     KCVT01000171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18878:13908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77696.1"
                     /translation="CVQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc gttcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000172             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14243:12741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000172
VERSION     KCVT01000172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14243:12741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    55..391
                     /note="immunoglobulin light chain variable region"
     V_region        55..391
     V_segment       55..353
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77697.1"
                     /translation="CGQGTHLPWTF"
     J_segment       354..391
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT           92 a          107 c          109 g           86 t
ORIGIN      
        1 acatgggctc agctcctggg gctgctattg ctctgcgtcc ccggatccag tggggatgtt
       61 gtgatgactc agtctccact ctccctgtcc atcacccctg gacagccggc ctccatctcc
      121 tgcaggtcta gtcaaagcct tgtacacatc aatggaaaca catacttgag ttggtatcag
      181 cagaacccag gccaacctcc aaggcgccta atttatgagg tttctaaccg ggactctggg
      241 gtcccagaca gattcagcgg cagtggggca gggacagatt tcacactgaa aatcagcaga
      301 gtggaggctg aggatgttgg gctttattac tgcgggcaag gtacacacct tccgtggacg
      361 ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000173             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22884:9557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000173
VERSION     KCVT01000173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22884:9557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..450
                     /note="immunoglobulin light chain variable region"
     V_region        113..450
     V_segment       113..414
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <392..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77698.1"
                     /translation="CMQSLDFPLTF"
     J_segment       415..450
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>455
                     /gene="IGKC"
BASE COUNT          100 a          122 c          125 g          108 t
ORIGIN      
        1 acatggggca gagtacatgg gggatcacga ctcctcaggt caccttctca caatgaggct
       61 ccctgctcag ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt
      121 tatgacccag actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg
      181 caggtctagt cagagcctcc tggatagtga ggatggaaac acctatttgg aatggtacct
      241 gcagaagcca ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg
      301 agtcccagac aggttcagtg gcagtgggtc agacacagat ttcacactga aaatcagcag
      361 agtggagact gaggatgttg gggtttatta ctgcatgcag tctctagatt ttccgctcac
      421 tttcggtgga gggaccaagg tggagatcaa tcgag
//
LOCUS       KCVT01000174             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18262:5387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000174
VERSION     KCVT01000174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18262:5387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77699.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          124 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000175             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12639:19954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000175
VERSION     KCVT01000175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12639:19954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77700.1"
                     /translation="CLQGYSAPFTF"
     J_segment       379..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          105 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcttcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa actcctcagc gcctgatcta
      241 tgctgcatcc agtttggaga gtggggtccc atcaaggttc agcggcagtg gatctggcac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggttat agtgccccat tcactttcgg ccccgggacc aaactggata tcaaaagag
//
LOCUS       KCVT01000176             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:22468:18291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000176
VERSION     KCVT01000176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22468:18291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..313
                     /note="immunoglobulin light chain variable region"
     V_region        114..313
     V_segment       114..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77701.1"
                     /translation="CLQPLEFPWTF"
     J_segment       276..313
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           71 a           80 c           89 g           76 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt
      181 ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt
      241 ggggtttatt actgcttgca acctctagag tttccgtgga cgttcggcca agggaccaag
      301 gtggaaatca aacgag
//
LOCUS       KCVT01000177             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13423:5681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000177
VERSION     KCVT01000177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13423:5681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..436
                     /note="immunoglobulin light chain variable region"
     V_region        123..436
     V_segment       123..407
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77702.1"
                     /translation="CQQGHSYPWTF"
     J_segment       408..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>447
                     /gene="IGKC"
BASE COUNT          103 a          124 c          119 g          101 t
ORIGIN      
        1 acatggggga ggctggtcac accctgtgca ggagtcagtc tcagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctccttgggc tcctgctgct ctggctccca ggtgccagat
      121 gtgacatcca gatgacgcag tctccatcct ccctgtccgc atctgtagga gacacagtca
      181 cgatcacttg ccagtcgagt ctaggcattg gcaaattttt aaattggtat cagcagaaac
      241 cagggaaagc ccccaaactc ctgatctata gtgcatccag tttgcaaact gggattccct
      301 ctcggttcag cggcagtgga tctgggacgg atttcactct caccatcagc agcctgcagc
      361 ctgaagattt tgccgcttat tactgtcaac agggtcatag ttacccgtgg acgttcggcc
      421 aagggaccaa ggtggagatg aaacgag
//
LOCUS       KCVT01000178             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16611:11023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000178
VERSION     KCVT01000178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16611:11023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..404
                     /note="immunoglobulin light chain variable region"
     V_region        102..404
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77703.1"
                     /translation="CQKYSSSPFTF"
     J_segment       386..404
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           87 a          119 c          107 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttatt ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagtcac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccagactcc
      241 tcgtctatgg tgcatccagg agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagaa gtatagtagt tccccattca ctttcggccc cggg
//
LOCUS       KCVT01000179             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21703:11417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000179
VERSION     KCVT01000179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21703:11417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    167..333
                     /note="immunoglobulin light chain variable region"
     V_region        167..333
     V_segment       167..295
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <273..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77704.1"
                     /translation="CMQALEFPYSF"
     J_segment       297..333
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        334..>336
                     /gene="IGKC"
BASE COUNT           71 a           95 c           93 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcttccat ctcctgcagc cgggcctctg
      181 gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca
      241 gagtggaggc tgaggatgtt ggggtttatt actgcatgca agctctagag tttccctaca
      301 gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01000180             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14177:3562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000180
VERSION     KCVT01000180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14177:3562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77705.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000181             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8655:7201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000181
VERSION     KCVT01000181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8655:7201"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77706.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagtttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000182             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:26837:12679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000182
VERSION     KCVT01000182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26837:12679"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77707.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          120 c          110 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactctct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01000183             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15655:2680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000183
VERSION     KCVT01000183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15655:2680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77708.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctaatc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga gtggcacctg cagaagccag
      241 gccagtctct acaactcttg atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatttc tgcatgcagg ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000184             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22821:20415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000184
VERSION     KCVT01000184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22821:20415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77709.1"
                     /translation="CFQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           87 a          126 c          120 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtcttg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccttca tggtaatgga aacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacaact cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttc caagatatac agcttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000185             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23048:4625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000185
VERSION     KCVT01000185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23048:4625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77710.1"
                     /translation="CMQAREFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          127 c          116 g          102 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ttccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt cgatagtgag gaggggaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tctccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgctgg ggtttattac tgcatgcaag ctcgagagtt tccattcact ttcggccccg
      421 ggaccaaact ggacatcaaa cgag
//
LOCUS       KCVT01000186             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7239:18609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000186
VERSION     KCVT01000186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7239:18609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77711.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt gacagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000187             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15532:17950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000187
VERSION     KCVT01000187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15532:17950"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77712.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactaaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000188             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10588:5954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000188
VERSION     KCVT01000188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10588:5954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77713.1"
                     /translation="CLQGYIDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          112 c          109 g           98 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtcg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcaacctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000189             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22197:8385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000189
VERSION     KCVT01000189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22197:8385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77714.1"
                     /translation="CQQYNSLPYIF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          111 a          108 c          104 g           98 t
ORIGIN      
        1 acatggggag agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcaccatca tttgccgggc aagtcaggac
      181 attaacgttt atttaaattg gtatcagcag aaaccgggga aagcccctaa acccctgatc
      241 tattatagaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattactgt
      361 caacagtata atagtttacc gtacattttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000190             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14522:17189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000190
VERSION     KCVT01000190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14522:17189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77715.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01000191             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12003:13709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000191
VERSION     KCVT01000191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12003:13709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77716.1"
                     /translation="CQHSFRTPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          116 c          112 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcaat gtcacttgca gggctagtga
      181 gagcgttagc accaaattac attggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcgtccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggaacagat ttcactctca ccatcagcag cctgcagcct gaagatgtcg caacttttta
      361 ctgtcagcat agttttcgta ccccgtacag ttttggccag gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000192             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4917:8304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000192
VERSION     KCVT01000192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4917:8304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77717.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          112 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag aagtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaaac gcctgatcta
      241 tgctgcatcc agtttggaaa ggggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attattgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000193             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:23239:13363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000193
VERSION     KCVT01000193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:23239:13363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77718.1"
                     /translation="CQQYDSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          112 g           89 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggcgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000194             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:11002:14133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000194
VERSION     KCVT01000194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11002:14133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77719.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttagag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaggccag
      241 gccagtctcc acagctctta atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000195             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23581:14418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000195
VERSION     KCVT01000195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23581:14418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77720.1"
                     /translation="CQQYNSDPYTF"
     J_segment       348..385
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           93 a          104 c          101 g           90 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc aggtgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcagggcatt agaagttatt tagcgtggta tcagctgaga
      181 ccagggaaag ccccgaaggc cttaatctat tacgcgacca ttttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaggatt ttgcaactta tttctgtcaa cagtataaca gtgacccgta cacttttggc
      361 caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01000196             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22284:17743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000196
VERSION     KCVT01000196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22284:17743"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77721.1"
                     /translation="CQQYTSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          121 c          105 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 acgttagcag tcatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctaa
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttatcact
      361 gtcaacagta cactagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000197             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16909:13402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000197
VERSION     KCVT01000197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16909:13402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77722.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000198             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:28664:9859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000198
VERSION     KCVT01000198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:28664:9859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77723.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagtgga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01000199             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18469:7325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000199
VERSION     KCVT01000199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18469:7325"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77724.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000200             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21477:19725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000200
VERSION     KCVT01000200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21477:19725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77725.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01000201             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11991:21985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000201
VERSION     KCVT01000201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11991:21985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77726.1"
                     /translation="CMRALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ttatcactgc atgcgagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000202             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17128:7730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000202
VERSION     KCVT01000202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17128:7730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77727.1"
                     /translation="CQQYDSFPLTF"
     J_segment       387..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT           99 a          112 c          113 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 cttcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaccag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattttac aagccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gtacagagtt cactctcacc atcagcagcc tgcaacctga ggattttgcc acttattact
      361 gtcaacagta tgatagtttc ccgctgactt tcggtggggg gaccaaggtg gagatcagac
      421 gag
//
LOCUS       KCVT01000203             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13019:16427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000203
VERSION     KCVT01000203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13019:16427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77728.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actgtccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000204             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10335:7606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000204
VERSION     KCVT01000204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10335:7606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77729.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatgggggt tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000205             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11047:4299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000205
VERSION     KCVT01000205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11047:4299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77730.1"
                     /translation="CMQALEFPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttgggtt ttattattgc atgcaagctc tagagtttcc tcccactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000206             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12456:6375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000206
VERSION     KCVT01000206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12456:6375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77731.1"
                     /translation="CQQYNSDSLTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          115 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagca gttatttagc gtggtatcgg cagaagccag ggaaagctcc ggagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgg aacttattac
      361 tgtcaacagt ataacagtga ctcgctcact ttcggtggag ggaccaaggt ggagatcaga
      421 cgag
//
LOCUS       KCVT01000207             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14235:19349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000207
VERSION     KCVT01000207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14235:19349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77732.1"
                     /translation="CLQGDTAPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          115 c          112 g           94 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg caggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattaacgat tatttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat
      241 ttatgctgca tccagtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcag cttattactg
      361 tctacagggt gatactgccc cgttcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000208             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20634:6659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000208
VERSION     KCVT01000208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20634:6659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77733.1"
                     /translation="CQQYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          104 a          113 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa agcggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtctggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 gcagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01000209             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12178:4416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000209
VERSION     KCVT01000209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12178:4416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77734.1"
                     /translation="CLQGYNTPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          113 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagtt gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacctgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gaaaagctcc taagcgcctg
      241 atctatgctg tgtccagttt ggaaggtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagatcttgc gacttattac
      361 tgtctacagg gttataatac cccgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000210             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15880:6675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000210
VERSION     KCVT01000210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15880:6675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77735.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          117 c          103 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagacg gagtcaccat cacttgccgg ccaagtcagg
      181 acattggcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaaatcctga
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggactttgca acttattact
      361 gtcaacagta taatagttta ccactcactt tcggccccgg gaccaaactg gatgtcaaac
      421 gag
//
LOCUS       KCVT01000211             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18080:8412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000211
VERSION     KCVT01000211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18080:8412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77736.1"
                     /translation="CMQAREFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          118 c          124 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccagtct ccctgcccgt cactcttgga gagccggcct ccatctcctg catgtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatgtgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttcctacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctcgagagt ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000212             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:10970:10226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000212
VERSION     KCVT01000212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10970:10226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77737.1"
                     /translation="CVQAIAFPYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           93 a          120 c          120 g          101 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgccc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggaaaca cctatttcca ctggtacctg cagaagccag gccagtctcc
      241 gcagctcctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcaag ctatagcgtt tccgtacagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01000213             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20901:18805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000213
VERSION     KCVT01000213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20901:18805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77738.1"
                     /translation="CQQGYGFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          118 c          100 g          103 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc catgtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cgcgatcact tgcctggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accatggaaa gcccctaaac tcctgatcta
      241 tacggcatcc aatttacatg gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca acagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat ggttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000214             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22507:7950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000214
VERSION     KCVT01000214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22507:7950"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77739.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           94 t
ORIGIN      
        1 atggggagga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000215             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15098:14619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000215
VERSION     KCVT01000215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15098:14619"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77740.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          113 a          118 c          105 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcac
      181 gatattaaca actggttggc ctggtatcaa cagaaaccag ggaaagcccc taaggtcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggttct
      301 gggacagatt tcactctcac catcaacaac ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacaac atgatgattc ccctcggacc ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000216             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7155:16636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000216
VERSION     KCVT01000216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7155:16636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    132..278
                     /note="immunoglobulin light chain variable region"
     V_region        132..278
     V_segment       132..240
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77741.1"
                     /translation="CLQFKSFPYSF"
     J_segment       241..278
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>281
                     /gene="IGKC"
BASE COUNT           67 a           77 c           70 g           67 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatcacggt tcagcggcag tggatctggg acagaattca ctctcattat
      181 cagcagcctg cagcctgaag attttgcaac ttattactgt ctacagttta aaagtttccc
      241 gtacagtttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000217             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17281:10392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000217
VERSION     KCVT01000217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17281:10392"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77742.1"
                     /translation="CQHGYGIQLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagcat ggacatgagg gcccccactc agctcctggg
       61 gttcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatctct tgccaggcga gtcaggacat
      181 tagcaatgat ttagcctggt atcagcagaa accgggaaaa gcccctaggc tcctgatgta
      241 taaggcatcc gctttgcaga ttggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca acagcctgca gcctgaagat tttgcaactt actactgtca
      361 acatggttat ggtatccagc tcactttcgg tggagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01000218             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14396:12023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000218
VERSION     KCVT01000218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14396:12023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77743.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggttcctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgacgt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000219             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7329:8351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000219
VERSION     KCVT01000219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7329:8351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77744.1"
                     /translation="CQQYDSFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          115 c          101 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatat aaatcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcagcagta tgatagtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000220             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21453:12751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000220
VERSION     KCVT01000220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21453:12751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77745.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000221             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14614:18444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000221
VERSION     KCVT01000221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14614:18444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77746.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          113 c          101 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaactggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000222             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17770:14551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000222
VERSION     KCVT01000222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17770:14551"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..377
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77747.1"
                     /translation="CQHSYGTLTWRF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgcgg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gggacagagt caccatcact tgcaggacaa gtgagaacgt
      181 taagaactat ttacattggt atcagcaaaa accagggaaa gccccaaggc tcctgatcta
      241 tgctgcatcc actttgcaaa gtggggtccc atcaaggttc accggcagtg gatctggggc
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 acatagttat ggtaccctca cgtggaggtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01000223             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:7667:20341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000223
VERSION     KCVT01000223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7667:20341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77748.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          119 c          109 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagcc
      181 acgatataaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaagctcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000224             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6763:15745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000224
VERSION     KCVT01000224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6763:15745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..393
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77749.1"
                     /translation="CMQALDFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggct agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaagtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaagatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agacttcccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000225             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15710:11439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000225
VERSION     KCVT01000225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15710:11439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77750.1"
                     /translation="CQQHNGYPPTF"
     J_segment       381..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          106 a          118 c          105 g           89 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag tcagggcatt
      181 acgaatgatt tagcctggta tcaacagaaa ccaggtaaag ccccgaagcc cctgatctat
      241 tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttattgtcaa
      361 cagcataatg gataccctcc gacgttcggc caagggacca gggtggaaat caaacgag
//
LOCUS       KCVT01000226             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19967:4502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000226
VERSION     KCVT01000226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19967:4502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..402
                     /note="immunoglobulin light chain variable region"
     V_region        100..402
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77751.1"
                     /translation="CQQVYTNPFTF"
     J_segment       384..402
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           90 a          107 c          100 g          105 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtct
      121 ccatctgcct tgtctgcatc tgtaggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata gttatttagg gtggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg tatccagatt gcaaagtgga attccctctc ggttcagcgg cagtggatcc
      301 gggacagatt tcactctcac cattagtagt ctgcagcctg acgattctgc agtttattac
      361 tgtcaacagg tttatactaa tccattcact ttcggccccg gg
//
LOCUS       KCVT01000227             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17713:13373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000227
VERSION     KCVT01000227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17713:13373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..277
                     /note="immunoglobulin light chain variable region"
     V_region        185..277
     V_segment       185..237
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77752.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       245..277
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           84 a           54 c           62 g           80 t
ORIGIN      
        1 acatggggat tcttcagaag gaaatcaatt gtcaagaaaa ttcttcctga gaatttttat
       61 cagggaagat taacacaaaa caggaatcaa aaatagaaga gactggaagc tgatacttta
      121 accaggcggg tgcttacctg ttctcttgag gatggacttc tattctcatc tgttctctcc
      181 cagttgcagc ctgaagattt tgcaacttat tattgtcaac cgtttaaaag ttacctttcg
      241 gtccctttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000228             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16272:6262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000228
VERSION     KCVT01000228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16272:6262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77753.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          118 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01000229             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13861:6015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000229
VERSION     KCVT01000229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13861:6015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77754.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          118 c          117 g          109 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg aatccagtgg ggacattgtg atgacgcaga
      121 ctccatactc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctactc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtctcagaca
      301 ggttcagtgg caatgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt tgagatcaaa cgag
//
LOCUS       KCVT01000230             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5170:9683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000230
VERSION     KCVT01000230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5170:9683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77755.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000231             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19418:12661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000231
VERSION     KCVT01000231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19418:12661"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77756.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          111 c          103 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacgt
      181 taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaatgcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000232             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21073:7619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000232
VERSION     KCVT01000232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21073:7619"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77757.1"
                     /translation="CQQYDSDTRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgttcacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cacgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000233             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13182:9015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000233
VERSION     KCVT01000233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13182:9015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77758.1"
                     /translation="CQQYNSLPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          117 c          105 g          100 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgag attcagatga cccagtctcc
      121 atcctccctg tctgcctctg tcggggacag agccaccatc acttgccggg caagtcagga
      181 cattagtgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aactcctgat
      241 ttattatgca tcccgtttgg agaatggggt cccatcaagg ttcagcggct ctggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcaacctgaa gattctgcag cttattactg
      361 tcagcagtat aatagtttac cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01000234             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:11266:12315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000234
VERSION     KCVT01000234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11266:12315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77759.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          109 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000235             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11806:13979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000235
VERSION     KCVT01000235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11806:13979"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77760.1"
                     /translation="CGQGTHLPLTF"
     J_segment       390..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g           96 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtgc tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 tatagcactg gaaacacata cttgagttgg tatcaacaga agccaggcca acctccgagg
      241 cgcctaattt atgaggtttc ttaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      361 tattactgcg ggcaaggtac acaccttccg ctcactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01000236             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15116:14229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000236
VERSION     KCVT01000236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15116:14229"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77761.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          118 c          126 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acgtagtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag tcggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctggg
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000237             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14682:10684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000237
VERSION     KCVT01000237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14682:10684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..389
                     /note="immunoglobulin light chain variable region"
     V_region        126..389
     V_segment       126..351
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77762.1"
                     /translation="CQQYNSDPRTF"
     J_segment       355..389
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>392
                     /gene="IGKC"
BASE COUNT           95 a          110 c          102 g           85 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccatc acttgtcggg cgagtcaggg cattcgcagt tatttagcgt ggtatcagca
      181 gaaaccaggg aaagccccga agcccttgat ctattacgcg tccactttgg aaagtggggt
      241 cccatcaagg ttcagcggca ctggatctgg gacagaattc actctcacca tcagcagcct
      301 gcagcctgaa gattttgcaa cttatttctg tcaacagtat aacagtgacc cgcgcacttt
      361 cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000238             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22097:14133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000238
VERSION     KCVT01000238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22097:14133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77763.1"
                     /translation="CLQYKSFPYTF"
     J_segment       390..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          115 c          101 g           99 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtgaag
      181 gtattaccag ttatttacat tggtttcagc agaaaccagg gagagcccct aagctcctga
      241 tctatgaaac attcagtttg acaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagtttc ccgtacacct ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01000239             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20720:11560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000239
VERSION     KCVT01000239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20720:11560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77764.1"
                     /translation="CLQSKNSPWTF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca atggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcgt ctgcagagcc agtgagagtg
      181 tcaatgtctt tggaataaac ctcattcact ggtatcagca gaaaccagga caacctccta
      241 aacccctgat ttaccaagca tccaataaag aaactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaagctgac gatgctgcag
      361 attattactg tctgcagagt aagaattctc cgtggacgtt tggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01000240             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:25200:9764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000240
VERSION     KCVT01000240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25200:9764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77765.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          118 c          107 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gctagtcagg
      181 acattagtaa ttttttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg ggaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga cgattttgcg acttatcatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000241             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9472:18559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000241
VERSION     KCVT01000241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9472:18559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77766.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctttaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01000242             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11507:16893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000242
VERSION     KCVT01000242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11507:16893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77767.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000243             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16226:4671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000243
VERSION     KCVT01000243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16226:4671"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77768.1"
                     /translation="CMQSLEIPPSF"
     J_segment       408..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacgcagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccacccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggcg tttattactg catgcaatct ctagagattc ctcccagttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000244             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14937:2043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000244
VERSION     KCVT01000244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14937:2043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..233
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77769.1"
                     /translation="CQQYDSDSLTF"
     J_segment       238..275
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           73 a           68 c           72 g           65 t
ORIGIN      
        1 acatggggtc accatcactt gtcgggcgac tcaggacatt cgcagttatt tagcgtggta
       61 tcaacagaaa ccagggaaag ccccgaggcc cttgatctat tacgcgtcca ctttggaaag
      121 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      181 cagcctgcag cctgaagatt tttcaactta ttactgtcaa caatatgaca gtgattcgct
      241 cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01000245             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14273:19961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000245
VERSION     KCVT01000245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14273:19961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77770.1"
                     /translation="CQQHDNSPPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          116 c          107 g           93 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 ttcctccctg tctgcatctg taggcgacag agtcaccatc acttgcagag ccagtcaggg
      181 tattagcgac tggttggcct ggtatcaaca gaaaccagga aaagccccta aactcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaaga ttcagtggaa gtggatctgg
      301 aacagatttc actctcacca tcagcagcct gcaggctgaa gatttcgcaa catatttctg
      361 tcaacagcat gataattccc ctcccacttt cggtggaggg actaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000246             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23128:5960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000246
VERSION     KCVT01000246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23128:5960"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..366
                     /note="immunoglobulin light chain variable region"
     V_region        87..366
     V_segment       87..329
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77771.1"
                     /translation="CQQDFGWPPTF"
     J_segment       332..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           87 a          103 c          105 g           74 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag gggaaagagc caccctctcc tgcagggcca
      121 gtcagactgt tggcagcgcc ttagcctggt accagcagaa acctgggcag actcacaaac
      181 tcctcattta tggtgcatcc agcagggcca ccggcatccc agacaggttc agtggcagtg
      241 ggtctggaac agagttcact ctcaccatca gtagtccgga gcctgaggat gttggagttt
      301 attactgtca gcaggatttt ggctggcctc cgacgttcgg ccaagggacc aaggtggaaa
      361 tcaaacgag
//
LOCUS       KCVT01000247             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12777:13930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000247
VERSION     KCVT01000247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12777:13930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77772.1"
                     /translation="CQQYNSLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          111 c          110 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattgaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacgttaac gtttatttaa attggtatca gcagaaaccg gggaaagccc ctaagcccct
      241 gatcttttat gcaaaccgtt tggaacgtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caagttattc
      361 ttgtcaacag tataatagtt taccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01000248             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10044:20622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000248
VERSION     KCVT01000248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10044:20622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77773.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgagactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtgcctgcag aagccaggcc
      241 agtctccaca gctcctgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattcctgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000249             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10005:2247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000249
VERSION     KCVT01000249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10005:2247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77774.1"
                     /translation="CQQYDNFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          109 c          105 g           95 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagcat ggacatgagg gtccccactc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctctca gcatctgtag gagacagagt caccatcacc tgccgggcga gtcaggacat
      181 taacaatttt ttaagttggt atcaacagaa accagggaaa gcccctaagc gcctgatcta
      241 ttatgcatcc cgtttggaga gtggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agattatact ctcaccatca gcagtctgca gcctgaagat attgcaacat attactgtca
      361 acagtatgat aatttcccgt acagttttgg ccaggggacc aaagtagaga tcaaacgag
//
LOCUS       KCVT01000250             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9368:11811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000250
VERSION     KCVT01000250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9368:11811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77775.1"
                     /translation="CQQNSNWPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          122 c          113 g           84 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctctggctc ccagatacca ccggagaaat agtgatgacg cagtctccag
      121 ccaccctgtc tttgtctcca ggagaaagag ccaccctctc ctgcagggcc agtcagagtg
      181 tcagcagcag cgtagcctgg taccagcaga aacctgggca ggctcccaga ctcctcatct
      241 atggtgcatc caacagggcc actggcatcc cagacaggtt cagtggcagt gggtctggga
      301 cagagttcac tctcaccatc agcagcctgg agcctgaaga tgttgcactt tattattgtc
      361 agcagaatag taactggcct ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000251             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13752:14406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000251
VERSION     KCVT01000251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13752:14406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77776.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatggtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000252             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:25608:21705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000252
VERSION     KCVT01000252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25608:21705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77777.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctcaaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000253             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11238:16169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000253
VERSION     KCVT01000253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11238:16169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77778.1"
                     /translation="CQQGYSYHPTF"
     J_segment       382..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT           93 a          119 c          108 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacttc cttatgacgc agtctccttc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tggcactaat ttaaattggt atcagcagag accaggaaaa gcccctaaac tcctgatcta
      241 tagggcttcc ggtttgcaga gtgggactcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcagt ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttaccatc ccactttcgg cggagggacc aaggtggaga tccaacgag
//
LOCUS       KCVT01000254             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9479:12633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000254
VERSION     KCVT01000254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9479:12633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..384
                     /note="immunoglobulin light chain variable region"
     V_region        63..384
     V_segment       63..346
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77779.1"
                     /translation="CQQHDNAPWTF"
     J_segment       347..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           96 a          107 c          103 g           81 t
ORIGIN      
        1 acatgggggt ccccgctcag ctcctggggc tcctgttgct ctggctccca ggtgccagat
       61 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      121 ccatcacttg cagagccagt cagagtatta acgactggtt ggcctggtat caacagagac
      181 cagggaaggc ccctaagctc ctgatctata gggcatccaa tttggaaaca ggggtcccat
      241 caaggttcag tggaagtgga tctgggacag atttcactct cagcatcagc agcctgcagc
      301 ctgaagatat cgcaacatat tactgtcagc agcatgacaa tgccccgtgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01000255             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18172:10562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000255
VERSION     KCVT01000255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18172:10562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77780.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01000256             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24874:3381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000256
VERSION     KCVT01000256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24874:3381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77781.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          117 c          122 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctgtgg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000257             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23796:15464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000257
VERSION     KCVT01000257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23796:15464"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77782.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagttccc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000258             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:24024:12343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000258
VERSION     KCVT01000258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:24024:12343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..327
                     /note="immunoglobulin light chain variable region"
     V_region        8..327
     V_segment       8..290
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <267..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77783.1"
                     /translation="CGQGTQLPPTF"
     J_segment       294..327
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>330
                     /gene="IGKC"
BASE COUNT           84 a           91 c           86 g           69 t
ORIGIN      
        1 acatggggtc tccactctcc ctgcccatca cccctggaca gccggcctcc atctcctgca
       61 ggtctagtca aagccttgtt cacatcaatg gaaacacata cttgagttgg tatcaccaga
      121 agccaggcca acctccaagg cgcctaattt atgaggtttc ttaccgggac tctggggtcc
      181 cagacagatt cagcggcagt ggggcaggga cagatttcac actgaaaatc agcagagtgg
      241 aggctgagga tgttggaatt tattactgcg ggcaaggtac acagcttcct cccacgttcg
      301 gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000259             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16152:24185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000259
VERSION     KCVT01000259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16152:24185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..376
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77784.1"
                     /translation="CLQYKSYAFSF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          111 c          100 g          103 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagcttat
      181 tatcaattat ttaaattggt ttcagcagaa accaggggaa gcccctaagc tcctgattta
      241 tggtgcatcc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagac tttgcaagtt attactgtct
      361 acagtataaa agttacgcat tcagtttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000260             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22569:4657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000260
VERSION     KCVT01000260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22569:4657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77785.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          126 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000261             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12575:8845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000261
VERSION     KCVT01000261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12575:8845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77786.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01000262             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6641:8260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000262
VERSION     KCVT01000262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6641:8260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77787.1"
                     /translation="CMQGLQTPYTF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accttgtcac aatgaggctc cctgctcagc
       61 tcctggggct gctaatgctc tgggtctctg cctccagtgg agatatcgtg atgacccaga
      121 ctccactctc gctgcccgtc acccttggag agccagcctc catctcctgc aggtctagtc
      181 agagccttct gaatagtaat ggatacagct atttgagttg gtacctgcag aggccaggcc
      241 agtctccaca tctgctgatc tattatggct ctagtcgggc ctccggggtc cccgacaggt
      301 tcagtggcag tgggtcaggc acagatttta cactgaaaat caccagggtg gaggctgacg
      361 acgtaggggt ttattactgc atgcaaggtc tacaaactcc gtacactttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000263             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:27842:9908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000263
VERSION     KCVT01000263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27842:9908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77788.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          116 g          110 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gatatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000264             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13694:23511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000264
VERSION     KCVT01000264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13694:23511"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..250
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77789.1"
                     /translation="CQHSHGSPITF"
     J_segment       252..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           81 a           69 c           73 g           67 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgcagggca agtgagaacg tttacaacta
       61 tttacattgg tatcagcaga aaccagggaa agcccctaag gtcctgatct atgctgcatc
      121 cactttgcaa agtggagtcc catcaaggtt cagcggcagt ggatctggga ctgatttcac
      181 tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc agcatagtca
      241 tggatcccct atcactttcg gtggagggac caaggtggag atcaaacaag
//
LOCUS       KCVT01000265             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16871:15049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000265
VERSION     KCVT01000265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16871:15049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..345
                     /note="immunoglobulin light chain variable region"
     V_region        9..345
     V_segment       9..308
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <285..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77790.1"
                     /translation="CMQALEFPWTF"
     J_segment       309..345
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>348
                     /gene="IGKC"
BASE COUNT           80 a           88 c           98 g           82 t
ORIGIN      
        1 acatgggcat tgtgatgacc cagactccag tctccctgcc cgtcaccctg ggagagccgg
       61 cctccatctc ctgccggtct agtcagagcc tcttggatag tgaggatgga aacacctatt
      121 tggaatggca cctgcagagg ccaggccagt ctccacagct cttgatttat gaggtttcct
      181 atcgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact gatttcacac
      241 tgaaaatcag cagagtggag gctgaggatg ttggtattta ttactgcatg caagctctag
      301 agtttccttg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01000266             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16775:21153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000266
VERSION     KCVT01000266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16775:21153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77791.1"
                     /translation="CMHTLEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcgt ccagtgggga gattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggacacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca ggtcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcatactc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000267             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15068:20347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000267
VERSION     KCVT01000267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15068:20347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77792.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          108 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc aaaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agcggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000268             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10056:5518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000268
VERSION     KCVT01000268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10056:5518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77793.1"
                     /translation="CQQYSSLPWTF"
     J_segment       381..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          107 a          109 c          108 g           97 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcacaatca cttgccgggc aagtcagggc
      181 attagcaatt atttaaattg gtatcagcag aaaccgggga aagcccctaa ggtcctgatg
      241 tattatacaa accgcttgga aagtgggatc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg gaacctgatg attttgcaac ttattactgt
      361 caacagtata gttctttacc gtggacgttc ggccaaggga ccaaggtgga attcaaacga
      421 g
//
LOCUS       KCVT01000269             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24197:8050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000269
VERSION     KCVT01000269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24197:8050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77794.1"
                     /translation="CQQYDSFPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          113 c          105 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct ataggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattatcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt caccctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatagtttt cctcccactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000270             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16119:17669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000270
VERSION     KCVT01000270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16119:17669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77795.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          125 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tttcctgcag gtcgagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcggtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000271             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17099:7594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000271
VERSION     KCVT01000271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17099:7594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77796.1"
                     /translation="CMQGLEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          116 c          126 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactccg
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagt
      181 ctcttggata gtgaggttgg agacacctat ttggagtggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtgtcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaaggtcta gagtttcctt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000272             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21367:17916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000272
VERSION     KCVT01000272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21367:17916"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77797.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          109 g           90 t
ORIGIN      
        1 acatgggggg gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000273             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25791:9492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000273
VERSION     KCVT01000273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25791:9492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77798.1"
                     /translation="CMQALEFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggcacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgacgtt tccagccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cctacagttt tggccagggg
      421 accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01000274             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10892:20747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000274
VERSION     KCVT01000274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10892:20747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77799.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          117 c          109 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccat atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01000275             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8133:20511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000275
VERSION     KCVT01000275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8133:20511"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77800.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          127 c          115 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggcct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01000276             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20524:7409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000276
VERSION     KCVT01000276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20524:7409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77801.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          113 c          111 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccggagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000277             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10612:7269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000277
VERSION     KCVT01000277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10612:7269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77802.1"
                     /translation="CLHYKSYPPTF"
     J_segment       382..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c           99 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagtagttat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acactataaa agttatcctc ccactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000278             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8210:8708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000278
VERSION     KCVT01000278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8210:8708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77803.1"
                     /translation="CQQYDKSPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          119 c          118 g           86 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagggtc accatcactt gcagagccag
      181 tcagggtatc agcaactggt tggcctggta tcaacagaaa ccagggagag cccctaacct
      241 cctgatgtat agggcgtcca atttgcaagg aggggtccca tcaaggttca gaggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaggatg tcgctacata
      361 ttactgtcaa cagtatgata agtcccctcc gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01000279             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11470:17546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000279
VERSION     KCVT01000279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11470:17546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77804.1"
                     /translation="CVQARDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactact aatgctctgg ctccctggat cccgtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttggggt ttattactgc gttcaagctc gagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000280             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20849:17668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000280
VERSION     KCVT01000280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20849:17668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77805.1"
                     /translation="CQQYDSDPFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          117 c          109 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag ctggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaagat tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ctattactgt
      361 caacagtatg acagtgatcc gttcactttc ggtgggggga ccaaggtaga catcaaacga
      421 g
//
LOCUS       KCVT01000281             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18302:9348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000281
VERSION     KCVT01000281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18302:9348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77806.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          119 c          103 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctt ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaacataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000282             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:13138:4151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000282
VERSION     KCVT01000282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13138:4151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..247
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77807.1"
                     /translation="CQQYDSDPFTF"
     J_segment       250..285
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           77 a           69 c           79 g           63 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gtcgggcgag tcagggcatt cgcagttatt
       61 tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat tacgcgtcca
      121 ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa cagtatgaca
      241 gtgacccgtt cactttcggt ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01000283             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20483:3034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000283
VERSION     KCVT01000283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20483:3034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..377
                     /note="immunoglobulin light chain variable region"
     V_region        98..377
     V_segment       98..339
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77808.1"
                     /translation="CQKYSSSPFTF"
     J_segment       342..377
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>380
                     /gene="IGKC"
BASE COUNT           89 a          105 c          106 g           80 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggggaaagag ccatcctctc
      121 ctgcaggacc agtcagagtg ttggcaccag cttagcctgg taccagcaga aacctgggca
      181 ggcccccagg ctcctcatct atggtgcatc tagcagggtc actggcatcc cagacaggtt
      241 ccgtggcagt gggtctggga cagagttcac tctcaccatc agcagcctgg agcctgaaga
      301 ttttgcagtt tattactgtc agaaatatag tagctccccg ttcactttcg gcggagggac
      361 caaggtggag atcaaacgag
//
LOCUS       KCVT01000284             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22247:14223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000284
VERSION     KCVT01000284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22247:14223"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77809.1"
                     /translation="CMQPLDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc agccttggag agccggcctc cattttctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga ggcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaac ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000285             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9414:7291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000285
VERSION     KCVT01000285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9414:7291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77810.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          118 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt ttgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000286             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7367:12055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000286
VERSION     KCVT01000286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7367:12055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77811.1"
                     /translation="CQRYSYSTWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          120 c          115 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagt ttggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagaggt atagttactc cacgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000287             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18559:13437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000287
VERSION     KCVT01000287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18559:13437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77812.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc cggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000288             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7249:4194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000288
VERSION     KCVT01000288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7249:4194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77813.1"
                     /translation="CQHSHGSPITF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           97 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggac acagcatgga catgagggcc tctgctcagc
       61 tcctagggct cctgctgctc tggctcccag gcgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agggcaagtg
      181 agaacgttta caactattta cattggtatc agcagaaacc agggaaagcc cctaaggtcc
      241 tgatctatgc tgcatccact ttgcaaagtg gagtcccatc aaggttcagc ggcagtggat
      301 ctgggactga tttcactctc accatcagca gcctgcagcc tgaagatgtt gcaacttatt
      361 actgtcagca tagtcatgga tcccctatca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000289             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18840:16790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000289
VERSION     KCVT01000289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18840:16790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77814.1"
                     /translation="CLQGYIIPYNF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          110 c          110 g          100 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tttttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat
      241 ttatgctgca tccagtttgg aaagtggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcgg cttattattg
      361 tctacagggt tatattatcc cgtacaattt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000290             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22875:14982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000290
VERSION     KCVT01000290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22875:14982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77815.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          119 c          116 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt acatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcagtag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000291             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17782:20317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000291
VERSION     KCVT01000291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17782:20317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77816.1"
                     /translation="CMQGTHLPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          101 a          122 c          113 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccact ggggatgttg tcatgactca gtctccactc
      121 tccctggcca tcacccctgg acaaccggcc tccatctcct gcaggtctag ttacggcctt
      181 atacacagtg atgggaaaac ctacttgaat tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tctatcaggt ttctaaccgg gactctgggg tcccactcag attcagcggc
      301 agtggggcgg ggacagattt cacactggaa atcagcagag tggaggctga agatgttgga
      361 aattattact gcatgcaagg tacacacctt ccgtacagtt ttggccaggg gaccgaagtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000292             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8982:16033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000292
VERSION     KCVT01000292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8982:16033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77817.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaatacc tatttggaat ggcaccggca gatgccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000293             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16592:19372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000293
VERSION     KCVT01000293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16592:19372"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77818.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          120 c          108 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000294             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14082:6444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000294
VERSION     KCVT01000294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14082:6444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77819.1"
                     /translation="CLQFKTYPNSF"
     J_segment       382..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          118 c          104 g           98 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctata ggagacactg tcaccatctc ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga agccagggaa agccccaaac ctcctcatct
      241 atgctgcatc cactttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc accagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tgcagtttaa aacttacccg aacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000295             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13149:21193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000295
VERSION     KCVT01000295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13149:21193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..430
                     /note="immunoglobulin light chain variable region"
     V_region        91..430
     V_segment       91..392
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77820.1"
                     /translation="CMQALEFPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           96 a          117 c          118 g          102 t
ORIGIN      
        1 acatgggact cctcaggtca ccttctcaca atgaggctcc ctgctcagct cctgggactg
       61 ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac tccactctcc
      121 ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtcaagtca gagcctcctg
      181 gatagtgagg atggaaacac ctatttgcac tggtacttga agaagccagg ccagtctcca
      241 caggtcttaa tttatgaggt ttccaaccgg gcctctggag tcccagacag gttcagtggc
      301 agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01000296             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15734:1821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000296
VERSION     KCVT01000296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15734:1821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77821.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000297             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25715:7690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000297
VERSION     KCVT01000297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25715:7690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77822.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           95 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc accagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01000298             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14766:12191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000298
VERSION     KCVT01000298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14766:12191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77823.1"
                     /translation="CMQALQFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tacaatttcc gtggacgttc ggccatggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000299             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17952:13626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000299
VERSION     KCVT01000299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17952:13626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..366
                     /note="immunoglobulin light chain variable region"
     V_region        86..366
     V_segment       86..326
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77824.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       334..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           98 a           90 c           92 g           89 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca ggatggacat gacggtcccc gcttatctcc
       61 tggggctcct tctgctctgg ctcccaggag acaaagtcac catcacttgc agggcaagtc
      121 aggacattgg taattattta aattggtatc agcagaaacc aggaaaagct cctaaggtcc
      181 tgatctatgg tgtatccaat ttacaaagtg gggtcccatc aaggttcagc ggcagtggat
      241 ctgggacaga tcttactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      301 attgtcaacc gtttaaaagt tacctttcgg tccctttcgg cggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01000300             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11620:7898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000300
VERSION     KCVT01000300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11620:7898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    54..375
                     /note="immunoglobulin light chain variable region"
     V_region        54..375
     V_segment       54..338
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77825.1"
                     /translation="CQQDYDWPPTF"
     J_segment       341..375
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>378
                     /gene="IGKC"
BASE COUNT           89 a          109 c           97 g           83 t
ORIGIN      
        1 acatgggaca gcttctcttc ctcctgctac tctggatccc agataccacc ggagatacag
       61 tgatgacgca gtctccagcc accctgtctt tgtctccagg ggaaagagcc accctctcct
      121 gcagggccag tcagagtgtt ggcagcacct tagtatggta ccaccagaaa cctgggcagg
      181 ctcccacgct cctcgtctat ggtacatcca tcagggccac cggcatccca gacaggttca
      241 gtgccagtgg gtctggaaca gagtttactc tcaccatcag cagcctggag actgaagata
      301 ttggagttta ttattgtcag caggattatg attggcctcc gacgttcggc caagggacca
      361 aggtggaaat caaacgag
//
LOCUS       KCVT01000301             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8547:15021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000301
VERSION     KCVT01000301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8547:15021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..282
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77826.1"
                     /translation="CQQYDSDSLTF"
     J_segment       287..324
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>327
                     /gene="IGKC"
BASE COUNT           81 a           85 c           84 g           77 t
ORIGIN      
        1 acatgggcca gatgacccag tctccatcct ccctgtctgc atctgttgga gacagagtca
       61 ccatcacttg tcgggcgact caggacattc gcagttattt agcgtggtat cagcagaaac
      121 cagggaaagc cccgaagccc ttgatctatt acgcgtccac tttggaaagt ggggtcccat
      181 caaggttcag cggcagtgga tctgggacag aattcactct caccatcagc agcctgcagc
      241 ctgatgattt tgcaacttat tactgtcaac agtatgacag tgattcgctc actttcggtg
      301 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01000302             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14745:8949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000302
VERSION     KCVT01000302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14745:8949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77827.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          121 c          116 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccact ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000303             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14729:12003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000303
VERSION     KCVT01000303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14729:12003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77828.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaagatgga gatcaaacga g
//
LOCUS       KCVT01000304             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22625:17440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000304
VERSION     KCVT01000304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22625:17440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77829.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          107 t
ORIGIN      
        1 acatgggctg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000305             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19289:6389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000305
VERSION     KCVT01000305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19289:6389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77830.1"
                     /translation="CQQGDSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          112 c          111 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcccgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtctccttc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagagattat ttaaattggt atcagcagca accggggaaa gcccctaaac tcctgatgta
      241 ttatgcaaac agtctggcaa gtggagtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagggtgac agttatcctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000306             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16695:10912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000306
VERSION     KCVT01000306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16695:10912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..367
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77831.1"
                     /translation="CQQGNSNPLTF"
     J_segment       368..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT          103 a          105 c          105 g           94 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tcctgctgct
       61 ctggctccca ggtgccagat gtgacattca gatgtcccag tttccatcct ccctgtctgc
      121 atctgtagga gacagagtca ccatcacttg ccgggcaagt caggccatta gcagttattt
      181 aaattggtat cagcagaaac cggggaaagc ccctaaactc ctgatatatt atggaaaaag
      241 tttggcaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcacc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agggtaatag
      361 taatcctctc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01000307             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12990:14568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000307
VERSION     KCVT01000307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12990:14568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77832.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000308             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12825:13399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000308
VERSION     KCVT01000308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12825:13399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77833.1"
                     /translation="CLQDIQFPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           90 a          122 c          120 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgttg actcagactc
      121 cagtctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccttca aactaatgga aacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacaact cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaagatg
      361 ttggggttta ttactgcttg caagatatac agtttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000309             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13354:4374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000309
VERSION     KCVT01000309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13354:4374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..296
                     /note="immunoglobulin light chain variable region"
     V_region        137..296
     V_segment       137..259
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <236..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77834.1"
                     /translation="CMQALEFPLTF"
     J_segment       260..296
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>299
                     /gene="IGKC"
BASE COUNT           67 a           78 c           84 g           70 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcagaagcct ctggagtccc agacaggttc agtggcagtg ggtcagacac
      181 tgatttcaca ctgaaaatca gcagagtgga ggctgaggat gttgggattt attactgcat
      241 gcaagctcta gagtttcctc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000310             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13355:10883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000310
VERSION     KCVT01000310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13355:10883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77835.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          112 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccgtc
      121 ctccctgtct gcatctgtag gagacagagt cagcatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000311             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21150:11873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000311
VERSION     KCVT01000311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21150:11873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..359
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77836.1"
                     /translation="CQQYDSDSLTF"
     J_segment       364..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           98 a          109 c          104 g           93 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctaggactcc tgctgctctg
       61 tctcccaggt gccaaatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtcacca tcacttgtcg ggcgactcag gacattcgca gttatttagc
      181 gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg cgtccatttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt atgacagtga
      361 ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000312             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10709:12379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000312
VERSION     KCVT01000312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10709:12379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77837.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcccccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacactt acttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000313             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5407:8762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000313
VERSION     KCVT01000313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5407:8762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77838.1"
                     /translation="CMQALEFPLTF"
     J_segment       350..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           98 c          110 g           92 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgtaggtcta
      121 gtcagagcct cttggatagt gaagatggaa atacctattt ggaatggcac cggcagatgc
      181 caggccagtc tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcactct gaaaatcagc agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttcctctg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01000314             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19012:3461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000314
VERSION     KCVT01000314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19012:3461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77839.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000315             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:3620:12328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000315
VERSION     KCVT01000315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3620:12328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77840.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaccga g
//
LOCUS       KCVT01000316             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21823:17411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000316
VERSION     KCVT01000316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21823:17411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77841.1"
                     /translation="CMQALEFPWTF"
     J_segment       275..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           73 a           80 c           86 g           76 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cacaactctt gatttttgaa gtttcctacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gactttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01000317             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:9935:14445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000317
VERSION     KCVT01000317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9935:14445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77842.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagacaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000318             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13831:23505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000318
VERSION     KCVT01000318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13831:23505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77843.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          121 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc cctgacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctaagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000319             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13668:15774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000319
VERSION     KCVT01000319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13668:15774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..321
                     /note="immunoglobulin light chain variable region"
     V_region        1..321
     V_segment       1..279
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77844.1"
                     /translation="CQQYDSDSLTF"
     J_segment       284..321
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>324
                     /gene="IGKC"
BASE COUNT           82 a           83 c           84 g           75 t
ORIGIN      
        1 acatggggat gacccagtct ccatcctccc tgtctgcatc tgtaggagac agagtcacca
       61 tcacttgtcg ggcgactcag gacattcgca gttatttagc gtggtatcag cagaaaccag
      121 ggaaagcccc gaagcccttg atctattacg cgtccacttt ggaaagtggg gtcccatcaa
      181 ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc ctgcagcctg
      241 aagattttgc aacttattac tgtcaacagt atgacagtga ttcgctcact ttcggtggag
      301 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000320             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14979:15884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000320
VERSION     KCVT01000320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14979:15884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77845.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          112 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtccgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagagaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacctattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000321             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12917:19401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000321
VERSION     KCVT01000321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12917:19401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77846.1"
                     /translation="CLQGYITPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          113 c          110 g           99 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg gcttattact
      361 gtctacaggg ttatattacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000322             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12311:12838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000322
VERSION     KCVT01000322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12311:12838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77847.1"
                     /translation="CQQGYGFPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          117 c          103 g          102 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcgcgatcac ttgcctggcg agtcaaggca
      181 ttggcaataa tttaaattgg tatcagcaga aaccagggaa agcccctaaa ctcctgattt
      241 atacggcatc caatttacat ggtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc aacagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tggttttcca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01000323             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20750:3831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000323
VERSION     KCVT01000323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20750:3831"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..276
                     /note="immunoglobulin light chain variable region"
     V_region        7..276
     V_segment       7..238
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77848.1"
                     /translation="CMQALEFPYSF"
     J_segment       240..276
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           71 a           61 c           81 g           66 t
ORIGIN      
        1 acatggggtc tagtcagagc ctcttggata gtgaggatgg aaacacctat ttggagtggc
       61 acctgcagaa gccaggccag tctccacaac tcttgattta tgacgtttcc aaccgggcct
      121 ctggagtccc agacaggttc agtggcagtg ggtcagacac tgatttcaca ctgaaaatca
      181 gcagagtgga ggctgaggat gttggggttt attactgcat gcaagctcta gagtttccct
      241 acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000324             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20254:10903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000324
VERSION     KCVT01000324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20254:10903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77849.1"
                     /translation="CQKYSSSPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          122 c          113 g           94 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccggccac cctgtctttg tctccagggg aaagagccat cctctcctgc aggaccagtc
      181 agagtgttgg caccagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatctagc agggtcactg gcatcccaga caggttccgt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtttatt
      361 actgtcagaa atatagtagc tccccgttca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000325             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:9373:6941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000325
VERSION     KCVT01000325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9373:6941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..401
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77850.1"
                     /translation="CQQNSNWPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          127 c          124 g           90 t
ORIGIN      
        1 acatgggggg tcagagctct ggggaggaac tgctcagtta ggacccagag ggaaccatgg
       61 aagccccagc acagcttctc ttcctcctgc tgctctggct cccagatacc accggagaaa
      121 tagtgttgac gcagtctcca gccaccctgt ctttgtctcc aggagaaaga gccaccctct
      181 cctgtggggc cagtcagagt gtcagcagca gcttagcctg gtaccagcag aaacctgggc
      241 aggctcccag actcctcatc tatggtgcat ccaacagggc cactggcatc ccaggcaggt
      301 tccgtggcag tgggtctggg acagagttca ctctcaccat cagcagcctg gagcctgaag
      361 atgttgcact ttattattgt cagcagaaca gtaactggcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000326             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20225:10862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000326
VERSION     KCVT01000326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20225:10862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77851.1"
                     /translation="CQQGDSYPLTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          113 c          115 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgtcccagtc
      121 tccttcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaga gattatttaa attggtatca gcagcaaccg gggaaagccc ctaaactcct
      241 gatgtattat gcaaacagtc tggcaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggttcagc ggcagtctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag ggtgacagtt atcctctgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000327             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:6986:19040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000327
VERSION     KCVT01000327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:6986:19040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77852.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactcta accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000328             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20459:7694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000328
VERSION     KCVT01000328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20459:7694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77853.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          118 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca actcttaata tttgaggttt cctaccgggc cactggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000329             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23455:10137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000329
VERSION     KCVT01000329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23455:10137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..405
                     /note="immunoglobulin light chain variable region"
     V_region        86..405
     V_segment       86..355
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77854.1"
                     /translation="CQQGYYTPFTF"
     J_segment       370..405
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>410
                     /gene="IGKC"
BASE COUNT           93 a          116 c          106 g           95 t
ORIGIN      
        1 acatggggga ggacacagca tggacatgag ggtccccgct cagttcctgg ggctcctgct
       61 gctctggctc ccaggtgccc gatgtgacat ccagatgacc cagtctccat cgtccctgtc
      121 tgcatctgta ggagacaaag tcaccatctc ttgccgaacc agtcagggta ttagcagctg
      181 gttagcctgg tatcagcaga aaccagggaa agcccctaag ctcctgatct ataaggcgtc
      241 cagtttggca agtggggtcc catcaaggtt cagcggcagt ggatctggga cggatttcac
      301 tctcaccatc agcagcctgc agcctgaaga ttttgctact tattattgtc aacagggtta
      361 ctatacccca ttcactttcg gccccgggac caaactggat atcaatcgag
//
LOCUS       KCVT01000330             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19507:5897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000330
VERSION     KCVT01000330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19507:5897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77855.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatagggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000331             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10041:4877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000331
VERSION     KCVT01000331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10041:4877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77856.1"
                     /translation="CQQHDNAPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          117 c          110 g           85 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcagcagca tgacaatgcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000332             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18685:15232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000332
VERSION     KCVT01000332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18685:15232"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77857.1"
                     /translation="CLQDIQLPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           88 a          123 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattatgat gactcagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc ataggaatgg gtacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacagc tcctgatcta tttcggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtgccagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgctt gcaagatata caacttccgc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000333             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14542:19903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000333
VERSION     KCVT01000333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14542:19903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..394
                     /note="immunoglobulin light chain variable region"
     V_region        73..394
     V_segment       73..356
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77858.1"
                     /translation="CQQYDSDPFTF"
     J_segment       359..394
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           95 a          108 c          104 g           90 t
ORIGIN      
        1 acatgggggg acatgagggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca
       61 ggtgccaaat gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga
      121 gacagagtca ccatcacttg tcgggcgagt cagggcattc gcagttattt agcgtggtat
      181 cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac tttggaaagt
      241 ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct caccatcagc
      301 agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag tgacccgttc
      361 actttcggtg gagggaccaa ggtagagatc aaacgag
//
LOCUS       KCVT01000334             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18049:4776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000334
VERSION     KCVT01000334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18049:4776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..435
                     /note="immunoglobulin light chain variable region"
     V_region        100..435
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77859.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttcttacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgta tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgtgga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccagggg
      421 accaaggtgg aaatcgaacg ag
//
LOCUS       KCVT01000335             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23440:4346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000335
VERSION     KCVT01000335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23440:4346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77860.1"
                     /translation="CQQHETYPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          121 c          110 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcag catcacttgt cgggccagtc
      181 agggcgttag cgattcttta gcctggtatc aacagaaact aggaaaagcc ccgaagcccc
      241 tgatctttta cgcatccaat ttgaaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacctatt
      361 actgtcaaca gcatgagact tacccgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000336             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17102:19133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000336
VERSION     KCVT01000336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17102:19133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77861.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtgtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tcttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000337             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15359:4339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000337
VERSION     KCVT01000337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15359:4339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..253
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77862.1"
                     /translation="CQQYNSDPFTF"
     J_segment       254..291
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>294
                     /gene="IGKC"
BASE COUNT           83 a           71 c           73 g           67 t
ORIGIN      
        1 acatgggatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag gacataagaa
       61 gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg atctattacg
      121 catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct gggacagaat
      181 tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac tgtcaacagt
      241 ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa cgag
//
LOCUS       KCVT01000338             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6973:9832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000338
VERSION     KCVT01000338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6973:9832"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77863.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          118 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagagagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000339             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12437:13461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000339
VERSION     KCVT01000339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12437:13461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77864.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000340             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:2568:12312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000340
VERSION     KCVT01000340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:2568:12312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77865.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          101 a          120 c          118 g           94 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagatat cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000341             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12720:20360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000341
VERSION     KCVT01000341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12720:20360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77866.1"
                     /translation="CQQYNSLPYIF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          106 a          109 c          103 g           99 t
ORIGIN      
        1 atggggagac ccagtcagga cacagcatgg acatgagtgt ccccgctcag ctcctggggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct
      121 ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacatta
      181 gcgttttttt aaattggtat cagcagaaac cggggaaagc ccctaaaccc ctgatctatt
      241 atgcaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat tactgtcaac
      361 agtataatag tttaccgtac atttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01000342             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15066:4881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000342
VERSION     KCVT01000342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15066:4881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..424
                     /note="immunoglobulin light chain variable region"
     V_region        104..424
     V_segment       104..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77867.1"
                     /translation="CQQYDSDSLTF"
     J_segment       387..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          104 a          117 c          112 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      181 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt tgcaacttat
      361 tactgtcaac agtatgacag tgattcgctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01000343             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22535:9194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000343
VERSION     KCVT01000343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22535:9194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77868.1"
                     /translation="CIQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tacaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000344             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18509:13627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000344
VERSION     KCVT01000344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18509:13627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77869.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cacaagccag
      241 gccagtctcc agagctcttg atttatgagg tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga ttggaggctg
      361 aggatgttgg gctttattac tgtatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggaggtcaaa cgag
//
LOCUS       KCVT01000345             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17447:20472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000345
VERSION     KCVT01000345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17447:20472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77870.1"
                     /translation="CQQYNSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          113 c          110 g           97 t
ORIGIN      
        1 acatggtgga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000346             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:23119:6709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000346
VERSION     KCVT01000346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23119:6709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77871.1"
                     /translation="CQKYISPPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          130 c          105 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aacttatatt gactcagtct
      121 ccagccaccc tgtctctgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 ctctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtatattac
      361 tgtcagaaat atattagtcc cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01000347             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12518:9985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000347
VERSION     KCVT01000347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12518:9985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77872.1"
                     /translation="CQQYHSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          106 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggtat
      181 tagtagttat ttaaattggt atcagcagaa accggggaaa gcccctaacc tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcaaatt atttctgtca
      361 acagtatcat agtctaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000348             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:10773:22941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000348
VERSION     KCVT01000348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10773:22941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77873.1"
                     /translation="CLQYKSYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          113 c           96 g          103 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacattagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggttat
      181 tatcaattat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgattta
      241 tgctgcatcc agattggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000349             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15802:12930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000349
VERSION     KCVT01000349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15802:12930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77874.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccacacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000350             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10615:15485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000350
VERSION     KCVT01000350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10615:15485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77875.1"
                     /translation="CMQAREFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          126 c          116 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttcg atagtgagga ggggaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtc tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgctgggg tttattactg catgcaagct cgagagtttc cattcacttt cggccccggg
      421 accaaactgg acatcaaacg ag
//
LOCUS       KCVT01000351             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7943:18663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000351
VERSION     KCVT01000351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7943:18663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77876.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggccacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000352             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21529:10845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000352
VERSION     KCVT01000352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21529:10845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..428
                     /note="immunoglobulin light chain variable region"
     V_region        92..428
     V_segment       92..390
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77877.1"
                     /translation="CMQGTHLPFTF"
     J_segment       391..428
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          119 c          111 g          102 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg ggatgttgtg atgactcagt ctccactctc
      121 cctgtctatc actcttggac aaccggcctc catttcctgc aggtctagtc acacccttgt
      181 acacagtgat gggaaaacct acttgaattg gtatcagcag aagccaggcc aacctccaag
      241 gcgcctaatt tatcaggttt ctaaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gaggctgagg atgttggagt
      361 ttattactgc atgcaaggta cacaccttcc attcactttc ggccccggga ccaaactgga
      421 tatcaaacga g
//
LOCUS       KCVT01000353             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9606:8980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000353
VERSION     KCVT01000353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9606:8980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77878.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          114 a          119 c          107 g           88 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcacgatatt aacaactggt tggcctggta tcaacagaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 ttctgggaca gatttcactc tcaccatcaa caacctgcag cctgaagata tcgcaacata
      361 ttactgtcaa caacatgatg attcccctcg gaccttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01000354             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10329:12992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000354
VERSION     KCVT01000354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10329:12992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77879.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000355             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9829:9560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000355
VERSION     KCVT01000355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9829:9560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77880.1"
                     /translation="CQQGHSYPWTF"
     J_segment       379..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          108 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc atctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccagtcga gtctaggcat
      181 tgtcaaattt ttaaattggt atcagcagaa accagggaaa gcccccaaac tcctgatcta
      241 tagggcatcc agtttgcaaa ctgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccgctt attactgtca
      361 acagggtcat agttacccgt ggacgttcgg ccaagggacc aaggtggaga tgaaacgag
//
LOCUS       KCVT01000356             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9361:16935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000356
VERSION     KCVT01000356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9361:16935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..361
                     /note="immunoglobulin light chain variable region"
     V_region        45..361
     V_segment       45..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <298..>333
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77881.1"
                     /translation="CMQALEFPPFTF"
     J_segment       324..361
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        362..>364
                     /gene="IGKC"
BASE COUNT           84 a           97 c           96 g           87 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccgtcacc
       61 cttggagagc cggcctccat ctcctgcagg tctagtcaga gcctcttgga tagtgaggat
      121 ggaaacacct atttggaatg gtacctgcag aagccaggcc agtctccaca gctcttgatt
      181 tatgaggttt ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac
      241 actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattattgc
      301 atgcaagctc tagagtttcc tccattcact ttcggccccg ggaccaaact ggatatcaaa
      361 cgag
//
LOCUS       KCVT01000357             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5238:4162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000357
VERSION     KCVT01000357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5238:4162"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77882.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acctggagtg gtatttgcat aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000358             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18829:8762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000358
VERSION     KCVT01000358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18829:8762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..432
                     /note="immunoglobulin light chain variable region"
     V_region        111..432
     V_segment       111..394
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77883.1"
                     /translation="CLQFKTFPYSF"
     J_segment       395..432
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT          100 a          121 c          108 g          106 t
ORIGIN      
        1 acatggggac ttcttgcagg agtcagacac agtcaggaca cagcatggac atgagggccc
       61 ccgctcatct cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga
      121 tgactcagtc tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atctcttgcc
      181 gggcaagtca gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc
      241 ctaagctcct catctatgct gcatccactt tggccggtgg ggtcccatca aggttcagcg
      301 gcagtggatc tgggacagac ttcactctca ccatcagcag cctgcagcct gaagattttg
      361 caacttatta ctgtctacag tttaaaactt tcccgtacag ttttggccag gggaccaaag
      421 tggagatcaa acgag
//
LOCUS       KCVT01000359             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7430:21111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000359
VERSION     KCVT01000359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7430:21111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77884.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggtgtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000360             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24721:3004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000360
VERSION     KCVT01000360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24721:3004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77885.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actaatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01000361             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15544:17255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000361
VERSION     KCVT01000361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15544:17255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77886.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggag agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01000362             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17503:11033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000362
VERSION     KCVT01000362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17503:11033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..416
                     /note="immunoglobulin light chain variable region"
     V_region        97..416
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77887.1"
                     /translation="CQQHDDSPRTF"
     J_segment       383..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>421
                     /gene="IGKC"
BASE COUNT          108 a          119 c          107 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgaca tccagctgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcacagc cagtcaggat
      181 attaatacct ggttggcctg gtatcaacag aaaccaggaa aagcccctaa actcctgatc
      241 tatagggcat ccaatttgga aacaggggtc ccatcgaggt tcggtggaag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg cagcctgaag atatcgcaac atattactgt
      361 caacagcatg atgattcccc tcggacgttc ggccaaggga ccaaggtgga aatcaagcga
      421 g
//
LOCUS       KCVT01000363             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:25316:13708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000363
VERSION     KCVT01000363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25316:13708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77888.1"
                     /translation="CQQYNSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          113 c          108 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gcagaaacca ggaaaagccc cgaaggcctt
      241 gatctattac gcatccattt tagaaagtgc ggtaccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag ccttcagtct gacgattttg caacttatta
      361 ctgtcaacag tataacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01000364             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11578:9997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000364
VERSION     KCVT01000364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11578:9997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77889.1"
                     /translation="CMQALEFPYSF"
     J_segment       405..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          122 c          119 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga gtggcacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgacg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccctacagt tttggccagg
      421 ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01000365             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23462:7824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000365
VERSION     KCVT01000365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23462:7824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77890.1"
                     /translation="CQQSYRYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atgtatcttg cgtccacttt acagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagatgctgc aacttattac
      361 tgtcagcaga gttatcgtta tccgctcact ttcggtggag ggacccaggt ggaaatcaat
      421 cgag
//
LOCUS       KCVT01000366             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8189:16941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000366
VERSION     KCVT01000366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8189:16941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..388
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77891.1"
                     /translation="CQQHNSYPRTF"
     J_segment       390..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT          106 a          118 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtaccaga tgtgacatcc agatgaccca
      121 gtctccatct tccttgtctg catctgtagg agacagagtc accatcactt gccaagccag
      181 tcagggtatt ggcaactggt tagcctggta tcggcagaaa ccagggaaag cccctaagct
      241 cctgatctat gctgcatcca gtttacaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcag cagcataata gttatcctcg gacgttcggc caagggacca aggtggaaat
      421 caagcgag
//
LOCUS       KCVT01000367             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19560:13351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000367
VERSION     KCVT01000367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19560:13351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77892.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          109 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggtg agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gactctgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctttagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000368             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24288:15583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000368
VERSION     KCVT01000368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24288:15583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77893.1"
                     /translation="CMQAREFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           94 a          116 c          122 g          107 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcactct tggagagccg gcctccatct cctgcatgtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat gtggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc tacctggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcga gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000369             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19204:10774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000369
VERSION     KCVT01000369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19204:10774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77894.1"
                     /translation="CMQYRHIPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          119 c          113 g          110 t
ORIGIN      
        1 acatggggtg atcacaactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagact
      121 ccattctccc tgtccgttag ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttga atagtgaaga cggaaacacc tatttggatt ggtacctgca gaggccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01000370             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16542:9229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000370
VERSION     KCVT01000370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16542:9229"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77895.1"
                     /translation="CLQYKSYPFTF"
     J_segment       378..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          107 a          113 c           96 g          102 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcaggttatt
      181 atcaattatt taaattggtt tcagcagaaa ccagggaaag cccctaagct cctgatttat
      241 gctgcatcca gattggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa gttacccatt cactttcggc cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01000371             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22696:15495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000371
VERSION     KCVT01000371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22696:15495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77896.1"
                     /translation="CQQDSHWPTF"
     J_segment       388..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           96 a          125 c          118 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctccta cagggccagt
      181 cagagtgtca gcagccggtt agcctggtac cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatgtttg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag acttcactct caccatcagc agcctggagc ctgaagatgt tgcgctttat
      361 ttttgtcagc aggatagtca ctggcctacg ttcggccaag ggaccaaggt ggaactcaaa
      421 cgag
//
LOCUS       KCVT01000372             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:7651:14059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000372
VERSION     KCVT01000372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7651:14059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77897.1"
                     /translation="CQQHADSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          117 c          112 g           90 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct tctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 agggtattag caactggttg gcctggtatc aacagagacc agggaaagcc cctaaggtcc
      241 tgatttatag gacatccaat ttggaaacag gggtcccatc aaggttcagt ggaaccggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttc gctacatatt
      361 actgtcaaca gcatgctgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000373             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:3589:8405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000373
VERSION     KCVT01000373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3589:8405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77898.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          123 c          118 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatg cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgcgga
      361 tgttggggtt tattactgca tgcaagctct agactttccc ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000374             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20557:17476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000374
VERSION     KCVT01000374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20557:17476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..323
                     /note="immunoglobulin light chain variable region"
     V_region        13..323
     V_segment       13..285
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77899.1"
                     /translation="CQQYNSLPYSF"
     J_segment       286..323
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>326
                     /gene="IGKC"
BASE COUNT           87 a           79 c           80 g           80 t
ORIGIN      
        1 acatgggagt cagacccagt ctccatcctc cctgtctgct tctgtaggag acagagtcac
       61 catcacttgc cgggcaagtc agggcgttaa cgtttattta aattggtatc agcagaaacc
      121 ggggaaagcc cctaagcccc tgatctttta tgcaaaccgt ttggaacgtg gggtcccatc
      181 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc
      241 tgaagatttt gcaagttatt attgtcaaca gtataatagt ttaccgtaca gttttggcca
      301 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01000375             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10420:14586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000375
VERSION     KCVT01000375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10420:14586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77900.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaactagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000376             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18553:14933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000376
VERSION     KCVT01000376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18553:14933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77901.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          113 c          110 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000377             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14538:21761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000377
VERSION     KCVT01000377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14538:21761"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77902.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacaactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000378             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12902:16707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000378
VERSION     KCVT01000378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12902:16707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77903.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcaaca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000379             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24195:13433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000379
VERSION     KCVT01000379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24195:13433"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77904.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccga gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01000380             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10989:18028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000380
VERSION     KCVT01000380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10989:18028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77905.1"
                     /translation="CMQALEFPLTF"
     J_segment       276..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           70 a           79 c           89 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cacgactctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctagagt ttcctctcac tttcggtgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01000381             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:11959:12186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000381
VERSION     KCVT01000381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11959:12186"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77906.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          120 c          115 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccatcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000382             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12914:9769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000382
VERSION     KCVT01000382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12914:9769"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77907.1"
                     /translation="CQQFSTYPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          117 c          112 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagtatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggatcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acaaagtcac catcacttgc cgagccagtc
      181 agggtattag cagctggtta gcctggtatc agcagaaacc agggaaagcc cctaagcccc
      241 tgatctataa ggcatccagt ttgcaaagtg gggtcccttc acggttcagc ggcagtggat
      301 ctgggacgga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtttagtact taccctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000383             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20957:14280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000383
VERSION     KCVT01000383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20957:14280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77908.1"
                     /translation="CMQALEFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          122 c          119 g          104 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggag tggcacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgacgt ttccagccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccctacagtt ttggccaggg
      421 gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01000384             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9045:12031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000384
VERSION     KCVT01000384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9045:12031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77909.1"
                     /translation="CLQYKTYPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          103 g          101 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgcaggagac actgtcacca tcacttgccg ggcaagtcag
      181 ggtattggga cctatttaaa ttggtttcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg catctagtct ggaaagtggg gtcccatcaa ggttcagcgg cagtggattt
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtctacagt ataaaactta tccattcacc ttcggccccg ggaccaaact ggatatcaaa
      421 ggag
//
LOCUS       KCVT01000385             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16360:10253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000385
VERSION     KCVT01000385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16360:10253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77910.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000386             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11468:20088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000386
VERSION     KCVT01000386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11468:20088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77911.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          116 c          106 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gtcaggatat
      181 taataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attattgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000387             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11021:3234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000387
VERSION     KCVT01000387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11021:3234"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77912.1"
                     /translation="CMQALEFPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          123 c          115 g          104 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gataatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttccattc accttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01000388             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8397:8561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000388
VERSION     KCVT01000388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8397:8561"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77913.1"
                     /translation="CMQALEFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          125 c          116 g          106 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgata atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccattcacct tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01000389             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13866:6093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000389
VERSION     KCVT01000389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13866:6093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77914.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000390             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18802:13677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000390
VERSION     KCVT01000390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18802:13677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77915.1"
                     /translation="CQQYDNFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          110 c          108 g           96 t
ORIGIN      
        1 acatgggggg agtcagtccc agtcaggaca cagcatggac atgagggtcc ccactcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctctcagcat ctgtaggaga cagagtcacc atcacctgcc gggcgagtca
      181 ggacattaac aattttttaa gttggtatca acagaaacca gggaaagccc ctaagcgcct
      241 gatctattat gcatcccgtt tggagagtgg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat tatactctca ccatcagcag tctgcagcct gaagatattg caacatatta
      361 ctgtcaacag tatgataatt tcccgtacag ttttggccag gggaccaaag tagagatcaa
      421 acgag
//
LOCUS       KCVT01000391             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12901:5929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000391
VERSION     KCVT01000391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12901:5929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77916.1"
                     /translation="CQQYDKSPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          118 c          115 g           86 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag ggtcaccatc acttgcagag ccagtcaggg
      181 tatcagcaac tggttggcct ggtatcaaca gaaaccaggg agagccccta acctcctgat
      241 gtatagggcg tccaatttgc aaggaggggt cccatcaagg ttcagaggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgag gatgtcgcta catattactg
      361 tcaacagtat gataagtccc ctccgacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01000392             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10457:12605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000392
VERSION     KCVT01000392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10457:12605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..394
                     /note="immunoglobulin light chain variable region"
     V_region        58..394
     V_segment       58..356
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77917.1"
                     /translation="CMQSIKDPFTF"
     J_segment       357..394
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           93 a          108 c          101 g           95 t
ORIGIN      
        1 acatgggctg ctcagctcct cgggctgttg atgctctggg tccctggatc cagtggggat
       61 attgtgatga cccagacccc actctcggtg cccgtcaccc ctggagagcc ggcctccatc
      121 tcctgcaggt ctagtcaaag ccttctccat agtaatggag acacctattt acattggtac
      181 cttcagaggt caggccagtc tccacggctc ctgatctata aagtaaccaa tcggctacct
      241 ggggtcccag acaggttcag tgacagtggg tcaggcacag atttcacact gaaaatcagc
      301 agggtggagc ctgaggatat tggtgtttat ttctgcatgc aaagtataaa agatccattc
      361 actttcggcc ccgggaccaa actggatatc aaacgag
//
LOCUS       KCVT01000393             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24579:18072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000393
VERSION     KCVT01000393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24579:18072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77918.1"
                     /translation="CMQGTQLLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g           95 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccaccctcc
      121 ctgcccatca cccctggaca accggcctcc atctcctgca ggtctagtca aagccttcta
      181 cacactgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg agactgagga tgttggagtt
      361 tattactgca tgcaaggtac acagcttctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01000394             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23356:11186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000394
VERSION     KCVT01000394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23356:11186"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77919.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          119 c          124 g          103 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactgtcc ctgcccgtca cccttggaga gccggcctcc atctcctgtg ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctctcga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000395             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:7384:11181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000395
VERSION     KCVT01000395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7384:11181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77920.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          102 a          120 c          112 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gagtctgaag
      361 atgttgggat ttattattgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01000396             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11195:4588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000396
VERSION     KCVT01000396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11195:4588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77921.1"
                     /translation="CQRYSYSTWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          115 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagcttg gtttggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tacatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtatatt
      361 actgtcagag gtatagttac tccacgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000397             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9918:9847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000397
VERSION     KCVT01000397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9918:9847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..389
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77922.1"
                     /translation="CQQFNNLPPTF"
     J_segment       392..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>429
                     /gene="IGKC"
BASE COUNT          106 a          113 c          114 g           96 t
ORIGIN      
        1 acatggggag gaggagtcag acccagtcag gacacagcat ggacatgagg gtccccgctc
       61 agctcctggg gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc
      121 agtctccatc ctccctgtct gcttctggag gagacagcgt caccatcagt tgccgggcaa
      181 gtcaggacat tagcatttat ttaaattggt ttcagcagaa accggggaaa gcccctaagc
      241 tcctgatcta tgatggaaac cgtttggaga ctggggtccc atcaaggttc agcggcagtg
      301 gatccgggac agaattcact ctcaccatca ccagcctgca acctgaagat tttggaactt
      361 attactgtca acagtttaat aatttacctc ccactttcgg cggagggacc aaggtggaga
      421 tcaaaggag
//
LOCUS       KCVT01000398             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15369:17299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000398
VERSION     KCVT01000398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15369:17299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77923.1"
                     /translation="CQQHADSPRTF"
     J_segment       381..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          106 a          117 c          110 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcaactgg ttggcctggt atcaacagag accagggaaa gcccctaagg tcctgatcta
      241 taggacatcc aatttggaaa caggggtccc atcaaggttc agtggaaccg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgct gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaaggag
//
LOCUS       KCVT01000399             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14508:15107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000399
VERSION     KCVT01000399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14508:15107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77924.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tcgagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000400             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8836:11015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000400
VERSION     KCVT01000400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8836:11015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77925.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          127 c          119 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac caacaaaaac ctgggcaggc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt
      361 tgcagtctat ttttgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000401             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17450:13420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000401
VERSION     KCVT01000401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17450:13420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77926.1"
                     /translation="CLQDIQLPLNF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           90 a          123 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctggggct gctggtgctc tggctccctg ggaccagtgg ggatattatg atgactcaga
      121 ctccactctc cctgtccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct gcataggaat gggtacacct atttgttttg gtacctgcag aagccaggcc
      241 agtctccaca gctcctgatc tatttcggtt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtgccag tgggtcaggc actgatttca cactgaaaat cagccgggtg gaggctgagg
      361 atgttggggt ttattactgc ttgcaagata tacaacttcc gctcaatttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000402             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20557:6714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000402
VERSION     KCVT01000402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20557:6714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77927.1"
                     /translation="CHQYNNLPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          114 c          103 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacatt tatttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctgat
      241 ctattatgca aatcgtttgg aaactggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcaacagcct gcaacccgaa gattttgcaa cttattactg
      361 tcaccagtat aataatttac cactcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000403             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11215:3190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000403
VERSION     KCVT01000403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11215:3190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77928.1"
                     /translation="CQQYDSDPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaagtgtga catccagatg acccagtctc
      121 catcctcctt gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agacaccagg gaaagccccg aaacccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatttg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000404             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22788:14320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000404
VERSION     KCVT01000404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22788:14320"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77929.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000405             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15525:17688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000405
VERSION     KCVT01000405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15525:17688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77930.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatactgagg atggaaatac ctatttggaa tggcaccggc agatgccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctgacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000406             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17030:14566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000406
VERSION     KCVT01000406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17030:14566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77931.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           91 a          118 c          123 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc ttgtgctctg gctcctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000407             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12648:3850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000407
VERSION     KCVT01000407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12648:3850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77932.1"
                     /translation="CMQSLEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          120 c          123 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttg cataagccag
      241 gccagtctcc gcagctcttg atttatgagg tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaat ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000408             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15491:18044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000408
VERSION     KCVT01000408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15491:18044"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77933.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccagttt ggaaagtggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcactctcac catcaacagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01000409             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:22630:19984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000409
VERSION     KCVT01000409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22630:19984"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..332
                     /note="immunoglobulin light chain variable region"
     V_region        11..332
     V_segment       11..295
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <272..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77934.1"
                     /translation="CQQDFDWPPTF"
     J_segment       298..332
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>335
                     /gene="IGKC"
BASE COUNT           77 a           95 c           92 g           71 t
ORIGIN      
        1 acatggggga gaagttgtga tgacgcagtc tccagccacc ctgtctttgt ctccagggga
       61 aagagccacc ctctcctgca gggccagtca gagtgttggc aacaccttaa cctggtacca
      121 gcacaaacct gggcaggctc ccaagctcct cctctatggt gcatccacca gggcctccgg
      181 catcccaggt aggttcagtg ccagtgggtc tggaacagag tttactctca ccatcagcag
      241 cctggagcct gaagatgttg gaatttatta ctgtcagcag gattttgact ggcctccgac
      301 gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000410             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:7970:13116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000410
VERSION     KCVT01000410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7970:13116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77935.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaataccta tttggaatgg caccggcaga tgccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctgacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000411             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23893:23068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000411
VERSION     KCVT01000411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23893:23068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77936.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg aggaaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000412             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18329:13697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000412
VERSION     KCVT01000412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18329:13697"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77937.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccgggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000413             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13462:7937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000413
VERSION     KCVT01000413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13462:7937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77938.1"
                     /translation="CQQYNSLPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          121 c           96 g           97 t
ORIGIN      
        1 acatggggag acccagccag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctctctgtct acttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taatacttat ttaaattggt atcagcagaa accggggaca gcccctaagc tcctgatcta
      241 ttatgcaaac cgtttgcaca gtggggtccc atcaagattc agcggcagcg gatctgggac
      301 agaattcact ctcaccatca gtagcccgca acctgaggat ttcgcaactt acttctgtca
      361 acagtataat tctttaccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000414             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18874:18767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000414
VERSION     KCVT01000414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18874:18767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77939.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagag
      121 tccactctcc ctgtccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgagat ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcacag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000415             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16622:10675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000415
VERSION     KCVT01000415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16622:10675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77940.1"
                     /translation="CQQYNSDPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          110 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaattgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagga attatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattaca catccatttt ggaaaatggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcagtctcac catcagcagc ctgcaggctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000416             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23928:11118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000416
VERSION     KCVT01000416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23928:11118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..395
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77941.1"
                     /translation="CMQSLDLPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          127 c          116 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcgtgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgcaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagaccttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01000417             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4908:14248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000417
VERSION     KCVT01000417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4908:14248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77942.1"
                     /translation="CLQESNWSYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata gtaccggaga aatagtggtg acacagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcaaaag caggttagcc tggtaccagc agaaacctgg gcaagctccc aggctcctca
      241 tgtatgatgc gtccagcagg gccactggca tcccagacag gttcactggc agcgggtctg
      301 ggccagagtt cactctcacc atcagcagcc tggagcctga agatgttgcg gtttatttct
      361 gtcttcagga gagtaactgg tcgtacagct ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000418             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8845:4089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000418
VERSION     KCVT01000418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8845:4089"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77943.1"
                     /translation="CQKYISSPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          130 c          106 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaacttata ttgactcagt
      121 ctccagccac cctgtctctg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcctctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtatatt
      361 actgtcagaa atatattagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01000419             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11279:10072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000419
VERSION     KCVT01000419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11279:10072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77944.1"
                     /translation="CLQYKSYPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          115 c          106 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagtagttct ttacattggt ttcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcactg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgctactt attactgtct
      361 acagtataaa agttacccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000420             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12850:13441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000420
VERSION     KCVT01000420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12850:13441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77945.1"
                     /translation="CMQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          109 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatctagtgg ggacattctg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatgttgag gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gttttatttc tgcatgcaaa gtctggagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000421             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21801:11723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000421
VERSION     KCVT01000421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21801:11723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77946.1"
                     /translation="CVQSSHIPFTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga agctccctgc tcagctcctg
       61 gggctgctaa tgctctggct ctctggatcc agtggggaaa ttctgatgac ccagactcca
      121 ctctccctgc ccgtcacacc tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaagatgg aaacacctat ttggattggt acctccagaa gccgggccag
      241 tctccacagc ccttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatcc gcagagtgca ggctgaggat
      361 gttggagttt attactgcgt gcaatcttca cacattccgt tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000422             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14961:7399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000422
VERSION     KCVT01000422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14961:7399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77947.1"
                     /translation="CLQYKSYPYSF"
     J_segment       388..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT          105 a          113 c          108 g          102 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtatg catctgtagg agacactgtc accatcactt gccgggcaag
      181 tcatggtttt agcacttatt taaattggtt tcagcagaaa ccagggaaag cccctaagct
      241 ccttatctct gctgcatcca gtttggagag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtataaaa gttacccgta cagttttggc caggggacca aagtggagat
      421 caagcgag
//
LOCUS       KCVT01000423             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20983:3518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000423
VERSION     KCVT01000423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20983:3518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77948.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcgtctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agccctcgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01000424             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13410:3244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000424
VERSION     KCVT01000424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13410:3244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77949.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaccc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000425             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22206:18892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000425
VERSION     KCVT01000425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22206:18892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77950.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtccccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000426             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24369:9241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000426
VERSION     KCVT01000426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24369:9241"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77951.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg ggaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000427             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25657:17524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000427
VERSION     KCVT01000427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25657:17524"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77952.1"
                     /translation="CQQIHSNPFTF"
     J_segment       383..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          112 c          104 g          103 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtgg gagacagagt caccgtctct tgccgggcaa gtcagaacat
      181 ttatagttat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatata
      241 tgatgtatcc agattgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaactt attactgtca
      361 acagattcat agtaacccat ttactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000428             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23704:4121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000428
VERSION     KCVT01000428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23704:4121"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77953.1"
                     /translation="CMQALQTPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          116 c          119 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgcct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcacc cttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgaa tagtaatgga tacaactatt tgagttggta cctgcagaag ccaggccagt
      241 ctccacatct tctgatctat tatggttcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgaaaatcag cagggtggag gctgaggacg
      361 taggggttta ttactgcatg caagctttac aaactccgta cagttttggc caggggacca
      421 gagtggagat caaacgag
//
LOCUS       KCVT01000429             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:3358:18588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000429
VERSION     KCVT01000429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:3358:18588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77954.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 gttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000430             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18728:3520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000430
VERSION     KCVT01000430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18728:3520"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77955.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          119 c          116 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc aggaccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000431             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15715:11627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000431
VERSION     KCVT01000431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15715:11627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77956.1"
                     /translation="CQHSHGSPITF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtgaga
      181 acgtttacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aaggtcctga
      241 tctatgctgc atccactttg caaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggactgattt cactctcacc atcagcagcc tgcagcctga agatgttgca acttattact
      361 gtcagcatag tcatggatcc cctatcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000432             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5575:14711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000432
VERSION     KCVT01000432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5575:14711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77957.1"
                     /translation="CQQGSSNPVTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          113 c          114 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgtcccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggccattagc agttatttaa attggtatca gcagaaaccg gggaaggccc ctaaactcct
      241 gatatattat tcaagtagtt tggcaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggcacagaa ttcactctca ccatcagcag cctgcagcct gaagactttg caacttatta
      361 ctgtcagcag ggcagtagta atcctgtcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000433             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25245:6937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000433
VERSION     KCVT01000433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25245:6937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77958.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcac cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000434             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12238:9755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000434
VERSION     KCVT01000434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12238:9755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77959.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          112 c          102 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000435             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20145:20046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000435
VERSION     KCVT01000435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20145:20046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77960.1"
                     /translation="CLQYKNFPLSF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          112 c          104 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatgggcat gagggccccc gctcatctcc
       61 tagggctctt gctgctctga ctcccaggtg ccaggtgtga catccagatg actcagtctc
      121 cgtcttccct gtctgcatct ctaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 atattaacag ttatttaaat tggtttcagc agaaaccagg gaaagcccct aagctcctga
      241 tctatggtgc atccagtttg gaaagtgagg tcccattaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttatttct
      361 gtctacagta taaaaatttc ccgctctctt tcggcggagg gaccagggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01000436             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22873:10441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000436
VERSION     KCVT01000436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22873:10441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77961.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          114 a          118 c          106 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 acgatattaa caactggttg gcctggtatc aacagaaacc agggaaagcc cctaaggtcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggtt
      301 ctgggacaga tttcactctc accatcaaca acctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca acatgatgat tcccctcgga ccttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000437             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10925:14122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000437
VERSION     KCVT01000437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10925:14122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77962.1"
                     /translation="CQQVLTNPAF"
     J_segment       387..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          113 c          108 g           99 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ctgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gatatccagg tgacccagtc
      121 tccatctgcc ttgtctgcat ctgtaggaga cagagtcacc atctcttgcc gggcaagtca
      181 gaacatttat aggaatttag cgtggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatctatgct gcatccagat tgcaaagtgg gtttccctct cggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcaa cctacagcct gaagattctg caatttatta
      361 ctgtcaacag gttcttacta acccggcgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01000438             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20632:4173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000438
VERSION     KCVT01000438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20632:4173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77963.1"
                     /translation="CLQYNSSPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          117 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacata gcatggacat gagggtccct gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcgagtcaga
      181 ctattagcag ctggttagac tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctttaaggc atccagtttg caaagtgggg tcccctcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtctacagta caatagtagc ccgctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000439             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15140:13531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000439
VERSION     KCVT01000439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15140:13531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77964.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcac tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000440             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12027:5028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000440
VERSION     KCVT01000440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12027:5028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..310
                     /note="immunoglobulin light chain variable region"
     V_region        8..310
     V_segment       8..268
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77965.1"
                     /translation="CQQYDSDSLTF"
     J_segment       273..310
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>313
                     /gene="IGKC"
BASE COUNT           79 a           80 c           81 g           73 t
ORIGIN      
        1 acatgggctc catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg
       61 gcgactcagg acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg
      121 aagcccttga tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc
      181 agtggatctg ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca
      241 acttattact gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg
      301 gagatcaaac gag
//
LOCUS       KCVT01000441             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:4156:19436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000441
VERSION     KCVT01000441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4156:19436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77966.1"
                     /translation="CQQYNSGPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c          100 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accagccaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtgccagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtggcccat tcactttcgg tcccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000442             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19237:12344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000442
VERSION     KCVT01000442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19237:12344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77967.1"
                     /translation="CQQYNSDPYSF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          111 c          107 g           95 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aattgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcaggac
      181 attaggaatt atttagcgtg gtatcagcag aaaccagtca aagccccgaa ggccttgatc
      241 tattacacat ccattttgga aaatggggtc ccatcaaggt tcagcggcgg tggatctggg
      301 acagaattca gtctcaccat cagcagcctg caggctgagg attttgcaac ttattactgt
      361 caacagtata acagtgaccc gtacagtttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000443             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23392:8274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000443
VERSION     KCVT01000443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23392:8274"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77968.1"
                     /translation="CQQRNGYPYMISF"
     J_segment       393..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          102 a          113 c          114 g          101 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagtt gatacagtct
      121 ccatcctccc tgtctgcgtc tgtaggagac agagtcacca tcacttgtcg ggcaagtcag
      181 gacattagca gttatttagc ctggtatcag cataaaccag ggaaagcccc taagctcctg
      241 atctataggg cgtccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtcaacagc ggaatggtta cccctacatg atcagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01000444             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13319:18350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000444
VERSION     KCVT01000444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13319:18350"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77969.1"
                     /translation="CLQPLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc ttgcaacctc tagagtttcc atggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000445             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17063:8314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000445
VERSION     KCVT01000445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17063:8314"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77970.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctactca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca cacctcttga tttatgaagt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000446             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7788:11387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000446
VERSION     KCVT01000446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7788:11387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77971.1"
                     /translation="CQQHDDSPRTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          110 a          118 c          107 g           86 t
ORIGIN      
        1 acatgggggc agtctcagac aggacacagc atggacacga gggtccccgc tcagctcctg
       61 gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcacagc cagccacgat
      181 ataaataact ggttggcctg gtatcaacag aaaccaggaa aagcccctaa gctcctgatc
      241 tatagggcat ccaatttgga aacaggggtc ccatcgaggt tcagtggaag tggatctggg
      301 acagatttca ctctcagcat cagcagcctg cagcctgaag atttcgcaac atattactgt
      361 caacagcatg atgattcccc tcggacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01000447             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22064:10318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000447
VERSION     KCVT01000447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22064:10318"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77972.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          115 c          109 g           87 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcaggata
      181 ttaacaactg gttggcctgg tatcaacaga aaccagggaa agcccctaag gtcctgatct
      241 atagggcatc cattttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000448             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:10101:13068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000448
VERSION     KCVT01000448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10101:13068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77973.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          126 c          123 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagcgcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcct agcctggtac cagcagaaaa ctgggcaggc
      241 tcccagactc ctcatgtttg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000449             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13248:9850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000449
VERSION     KCVT01000449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13248:9850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77974.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          113 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcaac tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000450             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18402:11448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000450
VERSION     KCVT01000450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18402:11448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77975.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000451             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18028:18898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000451
VERSION     KCVT01000451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18028:18898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77976.1"
                     /translation="CQQVYTNPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          112 c          102 g          104 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgaaatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagttat ttagggtggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgtatcc agattgcaaa gtggaattcc ctctcggttc agcggcagtg gatccgggac
      301 agatttcact ctcaccatta gcagcctgca gcctgaagat tctgcagttt attactgtca
      361 acaggtttat actaatccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000452             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:5337:9251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000452
VERSION     KCVT01000452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:5337:9251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77977.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          115 c          106 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgttg gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagcagttct ttacattggt ttcaacacaa accagggaaa gcccctagtc tcctgatcta
      241 tgctgtgtcc agtttggcag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000453             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17656:4296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000453
VERSION     KCVT01000453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17656:4296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77978.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcatccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000454             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:12409:9369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000454
VERSION     KCVT01000454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12409:9369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77979.1"
                     /translation="CQQGYNPPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          119 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 gtattagcag ctggttagcc tggtatcagc agaaaccagg gaaagcccct aaactcctca
      241 tctataaggc gtccaatttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacaggg ttacaatccc cctctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000455             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17270:13794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000455
VERSION     KCVT01000455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17270:13794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77980.1"
                     /translation="CQQYNSLPYIF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          111 c          105 g           99 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgtt tttttaaatt ggtatcagca gaaaccgggg aaagccccta aacccctgat
      241 ctattatgca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtacatttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000456             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:29175:11776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000456
VERSION     KCVT01000456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:29175:11776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77981.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000457             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20000:2629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000457
VERSION     KCVT01000457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20000:2629"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..384
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77982.1"
                     /translation="CQQRNGYPYMYSF"
     J_segment       390..428
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          104 a          113 c          114 g          100 t
ORIGIN      
        1 acatgggggg agttagaccc agtctggacg cagcatggac atcagggtcc tcgctcagct
       61 tctcgggctc ctgctgctct ggctcccagg tgccagatgt gacactcagt tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc ggacaagtca
      181 ggacattggc agttatttag cctggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctataag gcgtccagtt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcaa cctgcaggct gaagattttg cagtttatta
      361 ctgtcaacag cgtaatggtt acccgtacat gtacagtttt ggccagggga ccaaagtgga
      421 gatcaaacga g
//
LOCUS       KCVT01000458             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8435:5285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000458
VERSION     KCVT01000458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8435:5285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77983.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          116 c          112 g           88 t
ORIGIN      
        1 atgggggcag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 aggatattaa caactggttg gcctggtatc aacagaaacc agggaaagcc cctaaggtcc
      241 tgatctatag ggcatccatt ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000459             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:17696:10773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000459
VERSION     KCVT01000459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17696:10773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77984.1"
                     /translation="CIQSLEFPWTF"
     J_segment       276..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           70 a           82 c           87 g           76 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagtctc
      121 cacacctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggtttagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag ggtggaggct gaggatgttg
      241 gggtttacta ctgcatacaa tctctagagt ttccttggac gttcggccag gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01000460             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22271:9100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000460
VERSION     KCVT01000460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22271:9100"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77985.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagagg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000461             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:23827:7628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000461
VERSION     KCVT01000461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23827:7628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77986.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01000462             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:23351:12142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000462
VERSION     KCVT01000462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23351:12142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77987.1"
                     /translation="CQQYYDLFWTF"
     J_segment       387..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          115 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta ctgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agtatgttgg cagccactta gcctggtacc agcagaaacc tgggcaggcc cccaagctcc
      241 ttgtccacag tatagacttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattagaa gtctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtattatgac ttgttttgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000463             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:27527:8960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000463
VERSION     KCVT01000463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:27527:8960"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77988.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000464             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15484:11130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000464
VERSION     KCVT01000464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15484:11130"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77989.1"
                     /translation="CQQYDSDPRTF"
     J_segment       389..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT          103 a          117 c          114 g           92 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgcgca ctttcggtgg agggaccaag gtggagatca
      421 atcgag
//
LOCUS       KCVT01000465             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9720:22328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000465
VERSION     KCVT01000465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9720:22328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77990.1"
                     /translation="CMQGLEYPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          116 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgcggat ggaaaaacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtt tagagtatcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000466             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23761:12670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000466
VERSION     KCVT01000466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23761:12670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77991.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          102 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttagag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaggccag
      241 gccagtctcc acaactctta atatttgagg tttcctaccg ggccactgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000467             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8054:15022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000467
VERSION     KCVT01000467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8054:15022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77992.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcacatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000468             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10490:9470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000468
VERSION     KCVT01000468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10490:9470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77993.1"
                     /translation="CQQYSSLPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          107 c          114 g           97 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcataagt agttatttaa attggtatca acagagaccg gggaaagccc ctaaggtcct
      241 gatctattat acaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag gttgcaacct gaggattttg cagtttatta
      361 ctgtcaacag tatagttctt taccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000469             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16216:16871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000469
VERSION     KCVT01000469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16216:16871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77994.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgagaatt agcagagtgg aggctgagga
      361 tgttggggtt ttttactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000470             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15701:3391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000470
VERSION     KCVT01000470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15701:3391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77995.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttcctcca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000471             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24518:14584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000471
VERSION     KCVT01000471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24518:14584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77996.1"
                     /translation="CMQYRHIPFTF"
     J_segment       408..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggcccaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000472             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13930:4668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000472
VERSION     KCVT01000472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13930:4668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77997.1"
                     /translation="FQHSHGSPITF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          105 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 ttacaactat ttacattggt atcagcagaa accagggaaa gcccctaagg tcctgatcta
      241 tgctgcatcc actttgcaaa gtggagtccc atcaaggttc agcggcagtg gatctgggac
      301 tgatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactttca
      361 gcatagtcat ggatccccta tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000473             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14198:3793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000473
VERSION     KCVT01000473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14198:3793"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..417
                     /note="immunoglobulin light chain variable region"
     V_region        104..417
     V_segment       104..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77998.1"
                     /translation="CQQGHSYPWTF"
     J_segment       388..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>428
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g           96 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctccttggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgacgca
      121 gtctccatcc tccctgtccg catctgtagg agacacagtc acgatcactt gccagtcgag
      181 tctaggcatt ggcaaatttt taaattggta tcagcagaaa ccagggaaag cccccaaact
      241 cctgatctat agggcatcca gtttgcaaac tgggattccc tctcggttca gcggcagtgg
      301 atctgggacg gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgccgctta
      361 ttactgtcaa cagggtcata gttacccgtg gacgttcggc caagggacca aggtggagat
      421 gaaacgag
//
LOCUS       KCVT01000474             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:2729:12387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000474
VERSION     KCVT01000474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:2729:12387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV77999.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          124 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000475             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19394:18651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000475
VERSION     KCVT01000475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19394:18651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78000.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgctag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000476             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22229:6975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000476
VERSION     KCVT01000476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22229:6975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78001.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          117 c          122 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggga gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000477             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21212:10753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000477
VERSION     KCVT01000477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21212:10753"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78002.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaat catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000478             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18635:10173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000478
VERSION     KCVT01000478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18635:10173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78003.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          119 c          110 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaaatgg ggtcccatca aggttcagcg ccagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000479             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:5881:14634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000479
VERSION     KCVT01000479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:5881:14634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78004.1"
                     /translation="CQQHNTFPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          107 g           96 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttatttc
      361 tgtcaacagc ataatacttt cccgtacact tttggccagg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000480             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14005:9542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000480
VERSION     KCVT01000480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14005:9542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78005.1"
                     /translation="CLQFKTYPNSF"
     J_segment       385..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          118 c          106 g          101 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct cagctcctca
      241 tctatgctgc atccagtttg gccggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tgcagcctga agattttgca acttatttct
      361 gtctgcagtt taaaacttac ccgaacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000481             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13928:5060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000481
VERSION     KCVT01000481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13928:5060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78006.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          117 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcaccttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01000482             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11989:13773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000482
VERSION     KCVT01000482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11989:13773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78007.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000483             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11781:14195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000483
VERSION     KCVT01000483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11781:14195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78008.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atatcaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc tgcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaag agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000484             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14355:20428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000484
VERSION     KCVT01000484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14355:20428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..284
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78009.1"
                     /translation="CQQHDNSPWTF"
     J_segment       285..322
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           91 a           84 c           82 g           68 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc
       61 atcacttgca gagccagtca gagtattaac gactggttgg cctggtatca acagagacca
      121 gggaaggccc ctaagctcct gatctatagg gcatccaatt tggaaacagg ggtcccatca
      181 aggttcagtg gaagtggatc tgggacagat ttcactctca ccatcagcag cctgcagcct
      241 gaagatatcg caacatatta ctgtcaacag catgataatt ccccgtggac gttcggccaa
      301 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000485             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21146:20983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000485
VERSION     KCVT01000485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21146:20983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..372
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78010.1"
                     /translation="CQQYDDYPWTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac aaagtcacca tcacttgcca tgccagtcag
      181 ggtattagta gtcggttagt ctggtatcag cagaaagcag ggaaagcccc taagcccctg
      241 atgtatgatg catccagttt acacagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagcctg aagattttgc tacttattac
      361 tgtcaacagt atgatgatta cccgtggacc ttcggccaag ggaccaaggt ggaaatcaag
      421 cgag
//
LOCUS       KCVT01000486             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13854:8103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000486
VERSION     KCVT01000486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13854:8103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78011.1"
                     /translation="CLQGYTIPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          113 c          106 g           94 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccggacaa gtcagggcat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc gcctgatcca
      241 tgctgtatcc agtttggaaa gtggggcccc atcaaggttc agcggcagtg gatctgaaac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagggttat actatcccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000487             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:24286:13445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000487
VERSION     KCVT01000487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24286:13445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78012.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          122 c          115 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggttccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gttcacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttgga
      361 atttattact gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000488             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13350:13865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000488
VERSION     KCVT01000488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13350:13865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78013.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          120 c          121 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000489             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15000:6735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000489
VERSION     KCVT01000489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15000:6735"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78014.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttcgaatg gtacctgcaa aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000490             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18975:18345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000490
VERSION     KCVT01000490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18975:18345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..372
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78015.1"
                     /translation="CLQGDTAPFTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          115 c          115 g           95 t
ORIGIN      
        1 catgggggta ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tccttctgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatctt ccctgtctgc atcggcagga gacagagtca ccatcacttg ccgggcaagt
      181 cagggcatta acgattattt aagttggtat cagcagaaac caggaaaacc tcctaagcgc
      241 ctgatttatg ctgcatccag tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcagcttat
      361 tactgtctac agggtgatac tgccccgttc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01000491             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22291:5694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000491
VERSION     KCVT01000491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22291:5694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78016.1"
                     /translation="CMQALQTPRTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          102 a          119 c          114 g          104 t
ORIGIN      
        1 acatggggag atcagaactg ctcagttcac cttctcaaga tgaagttcca tgctcagctc
       61 ctgggactgt taatgctctg ggtctctgaa tccagtgggg atattgtgat gacccagact
      121 ccactctccc tgcccgtgac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctac atagtaatgg aaacacctat ttgtattggt acctgcagaa gccagggcag
      241 cctcctcggc tcctaatcta tagagtttcc acccggttct ctggagtgcc agacaggttc
      301 agtggcagtg gatcaggcac agacttcaca ctgaaaatca gccgcgtgga ggctgaggat
      361 gtcggggttt attactgcat gcaagcttta cagactcctc ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaactag
//
LOCUS       KCVT01000492             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15025:16206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000492
VERSION     KCVT01000492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15025:16206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..411
                     /note="immunoglobulin light chain variable region"
     V_region        98..411
     V_segment       98..381
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78017.1"
                     /translation="CLQGDSTPFTF"
     J_segment       388..411
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>422
                     /gene="IGKC"
BASE COUNT          101 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tatttaagtt ggtatcagca gaaaccggga aaagctccta agcgcctaat
      241 ctatgctgca tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcga cttattactg
      361 tctacagggt gatagtaccc cgttcacttt tggccagggg accaaagtgg acgtcaaacg
      421 ag
//
LOCUS       KCVT01000493             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25278:8444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000493
VERSION     KCVT01000493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25278:8444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78018.1"
                     /translation="CQHSYETPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          120 c          102 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatacagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgccg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcata gttatgaaac ccctttcact ttcggccccg ggaccaatct ggatatcaaa
      421 cgag
//
LOCUS       KCVT01000494             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10354:18836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000494
VERSION     KCVT01000494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10354:18836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78019.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggagg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000495             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15712:16864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000495
VERSION     KCVT01000495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15712:16864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..385
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78020.1"
                     /translation="CQQYDDYPWTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT          103 a          117 c          113 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccac atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acaaagtcac catcacttgc catgccagtc
      181 agggtattag tagtcggtta gtctggtatc agcagaaacc agggaaagcc cctaagcccc
      241 tgatgtatgc tgcatccagt ttacacagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacgga ttacactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgatgat tacccgtgga cgttcggcca agggaccaag gtggaaatca
      421 agcgag
//
LOCUS       KCVT01000496             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16489:8795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000496
VERSION     KCVT01000496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16489:8795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78021.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          122 c          120 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatg cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgcgga
      361 tgttggggtt tattactgca tgcaagctct agactttccc ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000497             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7938:4655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000497
VERSION     KCVT01000497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7938:4655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78022.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ccccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000498             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19771:15430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000498
VERSION     KCVT01000498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19771:15430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..406
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78023.1"
                     /translation="CQQYNSYPLTF"
     J_segment       407..444
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          109 a          124 c          113 g          101 t
ORIGIN      
        1 acatggggga ggctggtcac acttcatgca ggaatcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctggggc tccttctgct ctggctccca ggtgccagat
      121 gtgacattca gatgacccag tctccatcct ccctgtctgc atctgtggga gacacagtca
      181 ccatcacttg tcgggcaagt cagggcatta gcagttattt agcctggtat cagcagaaac
      241 cagggaaagc ccctaagcgc ctgatctatg ctgcatccac tttacaaagt ggggtcccat
      301 caagcttcag cggcagtgga tctgggacag atttcactct caccatcagc agcctacagc
      361 ctgaagattt tgcaacttat tactgtcaac agtataatag ttatccgctc actttcggcg
      421 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01000499             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22596:10959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000499
VERSION     KCVT01000499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22596:10959"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78024.1"
                     /translation="CQQYNSLPRTF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>420
                     /gene="IGKC"
BASE COUNT          107 a          110 c          109 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttagtcaata tttaaattgg tatcagcaga aaccggggaa agcccctaag gtcctcatct
      241 attatgtaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tattactgtc
      361 aacagtataa tagtttacct cggacgttcg gccaagggac caaggtggaa atcagacgag
//
LOCUS       KCVT01000500             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15283:6226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000500
VERSION     KCVT01000500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15283:6226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78025.1"
                     /translation="CQQYSDFLLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           95 a          126 c          111 g           91 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg atcccagata ccgccggaga aattgtcatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa cagccaccct ctcctgcagg gccagtgaga
      181 gtgttggcac cttcttagcc tggtaccaac agaaacctgg gcaggctccc aaactccttg
      241 tccatagtgc attcttcagg gcccctggca tcccagacag gttcagtggc agcgggtctg
      301 ggacagagtt cactctcacc atcaacaccc tggagcctga agatgttgga gtttatcact
      361 gtcagcagta tagtgacttc ctgctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000501             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14351:11727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000501
VERSION     KCVT01000501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14351:11727"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78026.1"
                     /translation="CLQGDTSPFTF"
     J_segment       383..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          111 c          111 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcagt tgccgggcaa gtcaggacat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgatcta
      241 tgctgcatcc agtttggaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gtctgaagat tttgcaagtt attactgtct
      361 acagggtgat acttccccgt ttactttcgg cggagggacc caggtggaga tcaaacgag
//
LOCUS       KCVT01000502             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13949:8625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000502
VERSION     KCVT01000502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13949:8625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78027.1"
                     /translation="CQQYNSGPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          115 c          104 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct tcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagag accaggcaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtggcccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000503             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22580:10036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000503
VERSION     KCVT01000503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22580:10036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78028.1"
                     /translation="CVQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc gttcaagctc tagagtttcc gtggactttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000504             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10838:11284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000504
VERSION     KCVT01000504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10838:11284"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78029.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          119 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc actggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattctgca acttatttct
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000505             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20526:12807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000505
VERSION     KCVT01000505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20526:12807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78030.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcggcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaagc
      421 gag
//
LOCUS       KCVT01000506             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24249:6921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000506
VERSION     KCVT01000506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24249:6921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78031.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          116 c          108 g           89 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagtcagga
      181 tattaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta aactcctgat
      241 ctatagggca tccaatttgg aatcaggggt cccatcgagg ttcggtggaa gtggatctgg
      301 gacagatttc agtctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01000507             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9265:18060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000507
VERSION     KCVT01000507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9265:18060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78032.1"
                     /translation="CQQYDSLPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          107 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 tagtagttat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatggaaat cgtttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgacgat tttgcaactt attactgtca
      361 acagtatgat agtttaccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000508             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23091:11970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000508
VERSION     KCVT01000508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23091:11970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78033.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccgt cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000509             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15257:6677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000509
VERSION     KCVT01000509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15257:6677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78034.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          120 c          124 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaatca cctacttgga atggtatttg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000510             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14132:6417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000510
VERSION     KCVT01000510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14132:6417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78035.1"
                     /translation="CLQGYTIPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          114 c          108 g           95 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg gacaagtcag
      181 ggcattagcg attatttaag ttggtatcag cagaaaccag gaaaagctcc taagcgcctg
      241 atccatgctg tatccagttt ggaaagtggg gccccatcaa ggttcagcgg cagtggatct
      301 gaaacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagg gttatactat cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000511             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23701:10568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000511
VERSION     KCVT01000511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23701:10568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78036.1"
                     /translation="CMQALEFPYTF"
     J_segment       348..384
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           99 c          106 g           95 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agagtccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      121 gtcagaccct cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc
      181 caggccagtc tcctcaactc ttgatttatg aggtttccta ccgggcctct ggagtcccag
      241 acagtttcag tggcagtggg tcagacactg atttcacact gaaaatcaac agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttccttac acttttggcc
      361 aggggaccac agtggagatc aaacgag
//
LOCUS       KCVT01000512             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16329:5979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000512
VERSION     KCVT01000512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16329:5979"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78037.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata tcctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000513             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24644:17132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000513
VERSION     KCVT01000513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24644:17132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..248
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78038.1"
                     /translation="CQQYNSDLFTF"
     J_segment       252..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           77 a           67 c           80 g           66 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgtcgggcg agtcagggca ttcgcagtta
       61 tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc
      121 cattttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtataa
      241 cagtgacctg ttcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000514             548 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16738:8828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000514
VERSION     KCVT01000514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 548)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16738:8828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    224..545
                     /note="immunoglobulin light chain variable region"
     V_region        224..545
     V_segment       224..503
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <485..>517
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78039.1"
                     /translation="CQQYDSDSLTF"
     J_segment       508..545
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        546..>548
                     /gene="IGKC"
BASE COUNT          137 a          139 c          135 g          137 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt aaggaaggga acattagaag tttacctaag
      121 ccagtgagct cagtactgcc tgccttttca gggaagttct cttactacat gattaattat
      181 ctggacattt gtttttatgt ttccaatctc aggtgccaaa tgtgacatcc agatgaccca
      241 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      301 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc
      361 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      421 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      481 ttactgtcaa caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      541 caaacgag
//
LOCUS       KCVT01000515             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25241:5657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000515
VERSION     KCVT01000515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25241:5657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78040.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000516             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19966:20192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000516
VERSION     KCVT01000516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19966:20192"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78041.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          124 c          112 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 gctcttggat agtgaggatg aaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcactttcg gccccgggac
      421 caaactggaa atcaaacgag
//
LOCUS       KCVT01000517             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16255:10079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000517
VERSION     KCVT01000517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16255:10079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78042.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccgcttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000518             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11608:10387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000518
VERSION     KCVT01000518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11608:10387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..403
                     /note="immunoglobulin light chain variable region"
     V_region        101..403
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78043.1"
                     /translation="CQKYSSSPFTF"
     J_segment       385..403
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           87 a          120 c          105 g           91 t
ORIGIN      
        1 acatggggga gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttattt tgactcagtc
      121 tccagccacc ctgtcttttt ctccagggga aagagccacc ctctcctaca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccagactcct
      241 cgtctatggt gcatccagga gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagaag tatagtagtt ccccattcac tttcggcccc ggg
//
LOCUS       KCVT01000519             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6352:13756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000519
VERSION     KCVT01000519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6352:13756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78044.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          105 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaagcag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01000520             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7921:18653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000520
VERSION     KCVT01000520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7921:18653"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78045.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctac agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000521             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11831:7967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000521
VERSION     KCVT01000521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11831:7967"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78046.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          123 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccacccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg cgtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000522             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17883:14050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000522
VERSION     KCVT01000522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17883:14050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78047.1"
                     /translation="CMQDIQFPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           91 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgca gagtaacggg aaaacccatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggaattta ttactgtatg caagatatac agtttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000523             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17195:8191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000523
VERSION     KCVT01000523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17195:8191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78048.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          108 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cactcttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttcctacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga agatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000524             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14310:24203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000524
VERSION     KCVT01000524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14310:24203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78049.1"
                     /translation="CQQYNSLPRTF"
     J_segment       383..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>421
                     /gene="IGKC"
BASE COUNT          107 a          110 c          110 g           94 t
ORIGIN      
        1 acatgggggg agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgccgggc aagtcagggc
      181 attagtcaat atttaaattg gtatcagcag aaaccgggga aagcccctaa ggtcctcatc
      241 tattatgtaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgagg attttgcaac ttattactgt
      361 caacagtata atagtttacc tcggacgttc ggccaaggga ccaaggtgga aatcagacga
      421 g
//
LOCUS       KCVT01000525             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:24993:14953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000525
VERSION     KCVT01000525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24993:14953"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78050.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000526             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15214:13339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000526
VERSION     KCVT01000526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15214:13339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78051.1"
                     /translation="CQQHDNAPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          116 c          116 g           85 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca gcatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcagcag catgacaatg ccccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000527             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20116:19349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000527
VERSION     KCVT01000527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20116:19349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78052.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcctggatc cagtgcggac attgtgatga cccagactcc
      121 actctccctg gccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggat
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000528             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5009:18241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000528
VERSION     KCVT01000528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5009:18241"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78053.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc aaaaacctgg gcaggctccc agactcctcc
      241 tctatggtgc atccaacagg gccactggct tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000529             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10562:17943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000529
VERSION     KCVT01000529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10562:17943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78054.1"
                     /translation="CQQHDNMPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          114 c          114 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca gagtcaccat cacttgcagg gccagtcagg
      181 gtattagcaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatagggc atggaatttg gaaacagggg tcccatcaag gttcagtgga agtggatccg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgataatatg ccgctcactt tcggtggagg gaccaaggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01000530             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14619:7429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000530
VERSION     KCVT01000530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14619:7429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78055.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          114 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg agcctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000531             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12349:4475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000531
VERSION     KCVT01000531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12349:4475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78056.1"
                     /translation="CLQYKFYPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>420
                     /gene="IGKC"
BASE COUNT          101 a          116 c           99 g          104 t
ORIGIN      
        1 acatggggca gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgca ggagacactg tcaccatcac ttgccgggca agtcagggta
      181 ttggttccta tttaaattgg tttcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc tagtctggaa agtggggtcc catcaaggtt cagcggcact ggatttggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tttcgcaact tattattgtc
      361 tacagtataa attttatcca ttcaccttcg gccccgggac caaactggat atcaaaggag
//
LOCUS       KCVT01000532             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8712:8545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000532
VERSION     KCVT01000532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8712:8545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78057.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          115 c          108 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcaggatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc attttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000533             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15317:21351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000533
VERSION     KCVT01000533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15317:21351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78058.1"
                     /translation="CQHSYGTPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          113 c          104 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctactc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtaggacaa gtcagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcgtcc aatttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ttcaccatca ccagcctgca acctgaagat gttgcaactt attactgtca
      361 gcatagttat ggtaccccgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000534             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:7488:10698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000534
VERSION     KCVT01000534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7488:10698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78059.1"
                     /translation="CQQFNNLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          107 a          112 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtcg atatttaaat tggtatcagc agaaaccggg gaaagcccct aggctcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cacactcacc atcaacagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagtt taataattta cctcggacgt tcggccaagg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01000535             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15135:6184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000535
VERSION     KCVT01000535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15135:6184"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78060.1"
                     /translation="CQQGYNYPWTF"
     J_segment       379..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT           99 a          118 c          107 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgccc gcatctgtgg gcgacacagt cacgatctct tgccaggcga gtcaaggcat
      181 tgacaataat ttaaattggt ttcagcagac accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat aattacccgt ggacgttcgg ccaagggacc aaggtggaaa tccaacgag
//
LOCUS       KCVT01000536             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18281:18930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000536
VERSION     KCVT01000536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18281:18930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78061.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          122 c          119 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccaggc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagcg tagcctggta ccagcagaaa cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000537             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:9218:10498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000537
VERSION     KCVT01000537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9218:10498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78062.1"
                     /translation="CQQYDSDSLSF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          120 c          119 g           98 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctggagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtatgacagt gattcgctca gtttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01000538             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17241:5294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000538
VERSION     KCVT01000538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17241:5294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78063.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          118 c          108 g           89 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt accagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000539             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13987:14660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000539
VERSION     KCVT01000539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13987:14660"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78064.1"
                     /translation="CQHSYNTPYSF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          117 c          101 g           95 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 tctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtcagaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agcccctaac ctcctgatct
      241 atgctgcatc cactttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtta taataccccc tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000540             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11395:5617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000540
VERSION     KCVT01000540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11395:5617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78065.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          109 c          101 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgattta
      241 ttatacaaat cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000541             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22499:18343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000541
VERSION     KCVT01000541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22499:18343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78066.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          115 g           89 t
ORIGIN      
        1 acatggggaa ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgcggatgtt ggactttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000542             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16054:3100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000542
VERSION     KCVT01000542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16054:3100"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78067.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          124 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000543             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12292:12286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000543
VERSION     KCVT01000543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12292:12286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78068.1"
                     /translation="CQQYNSDPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          116 c          102 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag taaccatcac ttgtcgggcg agtcaggaca
      181 taagaagtta tttagcgtgg tatcagcaga aaccaggcaa agccccgaag cccttgatct
      241 attacgcatc cgttttggaa agtggggtcc catcaaggtt cagtggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagtctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgaccca ttcactttcg gccccgggac caaactggat accaaacgag
//
LOCUS       KCVT01000544             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:26198:8249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000544
VERSION     KCVT01000544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:26198:8249"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    133..281
                     /note="immunoglobulin light chain variable region"
     V_region        133..281
     V_segment       133..244
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <221..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78069.1"
                     /translation="CMQALEFPLTF"
     J_segment       245..281
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>284
                     /gene="IGKC"
BASE COUNT           63 a           74 c           80 g           67 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa
      181 aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaag ctctagagtt
      241 tcctctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000545             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:21819:14920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000545
VERSION     KCVT01000545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21819:14920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78070.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000546             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23808:10194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000546
VERSION     KCVT01000546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23808:10194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78071.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtcgg tctagtcaga
      181 gcctcgtggc tagtgaggat ggaaacacct ctttggaatg gtatttgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat caccagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcagacga g
//
LOCUS       KCVT01000547             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20977:13369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000547
VERSION     KCVT01000547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20977:13369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78072.1"
                     /translation="CQQHNNYSPTF"
     J_segment       367..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           99 a          114 c          102 g           89 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccaccctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattagca atgatttagc
      181 ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg atctattacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagc ataataatta
      361 ctctcccact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000548             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19910:17805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000548
VERSION     KCVT01000548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19910:17805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78073.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          125 c          116 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgat aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcacc ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01000549             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18302:11903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000549
VERSION     KCVT01000549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18302:11903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78074.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccacccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000550             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24595:12724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000550
VERSION     KCVT01000550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24595:12724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..403
                     /note="immunoglobulin light chain variable region"
     V_region        101..403
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78075.1"
                     /translation="CQKYSSSPFTF"
     J_segment       385..403
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           86 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttattt tgactcagtc
      121 tccagccacc ctgtcttttt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccagactcct
      241 cgtctatggt gcatccagga gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagaag tatagtagtt ccccattcac tttcggcccc ggg
//
LOCUS       KCVT01000551             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10579:19557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000551
VERSION     KCVT01000551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10579:19557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78076.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000552             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7022:9613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000552
VERSION     KCVT01000552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7022:9613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78077.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       389..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          103 a          114 c          112 g          101 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acactcagtt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg gacaagtcag
      181 gacattagca gttatttagc ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctataagg cgtccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaggctg aagattttgc agtttattac
      361 tgtcaacagc gtattggtta cccgtacatg tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01000553             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15108:20783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000553
VERSION     KCVT01000553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15108:20783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78078.1"
                     /translation="CQKYSSSPPVFSF"
     J_segment       395..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>432
                     /gene="IGKC"
BASE COUNT           98 a          123 c          119 g           92 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcgggcc cccagggtcc
      241 tcatctatag tgtatccaac agggccactg gcatcccaga caggttcagt ggcggtgggt
      301 ctgggacaga gttcaccctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagaa gtatagtagc tccccaccgg tgttcagttt tggccagggg accaaagtgg
      421 agatcagacg ag
//
LOCUS       KCVT01000554             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15989:15659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000554
VERSION     KCVT01000554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15989:15659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78079.1"
                     /translation="CMQGIEYPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gatgctccct gctctgctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gtcagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggta tagagtatcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000555             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11491:6765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000555
VERSION     KCVT01000555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11491:6765"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..394
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78080.1"
                     /translation="CQQNSNWPLTF"
     J_segment       395..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          102 a          126 c          118 g           88 t
ORIGIN      
        1 acatgggggc tctggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc
       61 agcacagctt ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat
      121 gacgcagtct ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag
      181 ggccagtcag agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc
      241 caggctcctc atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg
      301 cagtgggtct gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc
      361 agtttattat tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01000556             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16590:6313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000556
VERSION     KCVT01000556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16590:6313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78081.1"
                     /translation="CLQGYSPPWTF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          110 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatccct tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagggttat agtcccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaccgag
//
LOCUS       KCVT01000557             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17942:12709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000557
VERSION     KCVT01000557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17942:12709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78082.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cgctgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000558             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16212:8762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000558
VERSION     KCVT01000558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16212:8762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..372
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78083.1"
                     /translation="SMHDYGWPTTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          113 c          116 g           93 t
ORIGIN      
        1 acatgggggg ctctgagcac cgcctgccag catgttcttg ggagttcagg tgcagctcct
       61 ctggagcctg gctttctgga gggcagtgag tggagacatc atcctgaacc agacgccagc
      121 atccctgact gcacctccag gagagacagt ctccatctcc tgccaagcca gagcagatgt
      181 acatggtgaa atatcttgga tccggataaa ccttgaacaa agacttgaac cccttttatc
      241 tcatgtcact accttggccc caggtgtcgc agcccggttc atcagcaagg ggagtggcac
      301 cagttatgtt ttcagcatca gtgacctgca gcctggggac tctggggact attactccat
      361 gcatgactat gggtggccaa ccactttcgg tggagggacc aaggtggaga tcaaacgaa
//
LOCUS       KCVT01000559             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21101:14526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000559
VERSION     KCVT01000559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21101:14526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..427
                     /note="immunoglobulin light chain variable region"
     V_region        96..427
     V_segment       96..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78084.1"
                     /translation="CGQGTHLLTF"
     J_segment       392..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           96 a          116 c          120 g           98 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt gggggtgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagtcggcc tccatctcct gtaggtctag tcaaagcctt
      181 gtacacagca atggatacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggctg ggacagattt cacactgaaa atcaacagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ctcactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01000560             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12514:19618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000560
VERSION     KCVT01000560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12514:19618"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78085.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat caccagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01000561             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17376:3990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000561
VERSION     KCVT01000561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17376:3990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78086.1"
                     /translation="CLQFKTYPNSF"
     J_segment       380..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           95 a          117 c          105 g          101 t
ORIGIN      
        1 acatggggga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatctctt gccgggcaag tcagggtatt
      181 agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctcagct cctcatctat
      241 gctgcatcca gtttggccgg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattctctc tcaccatcac cagcctgcag cctgaagatt ttgcaactta tttctgtctg
      361 cagtttaaaa cttacccgaa cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01000562             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14549:18719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000562
VERSION     KCVT01000562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14549:18719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78087.1"
                     /translation="CLQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgct tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000563             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16771:8136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000563
VERSION     KCVT01000563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16771:8136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78088.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          121 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt cgagtcagag
      181 cctcttggat ggtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagcca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000564             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22844:17375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000564
VERSION     KCVT01000564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22844:17375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78089.1"
                     /translation="CQHSHGSPITF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          114 c          107 g           96 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgagaacg
      181 tttacaacta tttacattgg tatcagcaga aaccagggaa agcccctaag gtcctgatct
      241 atgctgcatc cactttgcaa agtggagtcc catcaaggtt cagcggcagt ggatctggga
      301 ctgatttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtca tggatcccct atcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000565             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17212:12586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000565
VERSION     KCVT01000565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17212:12586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78090.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          116 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg agcctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000566             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25514:9194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000566
VERSION     KCVT01000566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25514:9194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..246
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78091.1"
                     /translation="CQQYDSDPFTF"
     J_segment       249..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           74 a           69 c           80 g           64 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg tcgggcgagt cagggcattc gctgttattt
       61 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccag
      121 tttggaaagt ggggtcccat caaggttcag cggcggtgga tctgggacag aattcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      241 tgacccgttc actttcggtg gagggaccaa ggtagacatc aaacgag
//
LOCUS       KCVT01000567             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18120:9378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000567
VERSION     KCVT01000567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18120:9378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78092.1"
                     /translation="CLQYKSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          112 c          104 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 taacagtttt ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctacatcc agtttggaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttaccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000568             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18111:8917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000568
VERSION     KCVT01000568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18111:8917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78093.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gctcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000569             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8447:6105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000569
VERSION     KCVT01000569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8447:6105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78094.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          127 c          120 g           86 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagaggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcaac agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000570             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:2160:15176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000570
VERSION     KCVT01000570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:2160:15176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78095.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01000571             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19014:18529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000571
VERSION     KCVT01000571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19014:18529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78096.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          130 c          110 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggaggac cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacatgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaccat caccagagtg gagcctgagg
      361 atcttggggt ttactactgc atgcaagctc tagaatttcc cttcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01000572             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14642:9450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000572
VERSION     KCVT01000572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14642:9450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..299
                     /note="immunoglobulin light chain variable region"
     V_region        8..299
     V_segment       8..262
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78097.1"
                     /translation="CQQGNSNPLTF"
     J_segment       263..299
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>302
                     /gene="IGKC"
BASE COUNT           86 a           69 c           77 g           70 t
ORIGIN      
        1 acatgggctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggc
       61 cattagcagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aactcctgat
      121 atattatgga aaaagtttgg caagtggggt cccatcaagg ttcagcggca gtggatctgg
      181 gacagaattc actctcacca tcaccagcct gcagcctgaa gattttgcaa cttattactg
      241 tcaacagggt aatagtaatc ctctcacttt cggcggaggg accaaggtgg agatcaaacg
      301 ag
//
LOCUS       KCVT01000573             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14310:16456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000573
VERSION     KCVT01000573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14310:16456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78098.1"
                     /translation="CMQGTHLPFTF"
     J_segment       394..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          100 a          120 c          111 g          103 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgatgactc agtctccact
      121 ctccctgtct atcactcttg gacaaccggc ctccatttcc tgcaggtcta gtcacaccct
      181 tgtacacagt gatgggaaaa cctacttgaa ttggtatcag cagaagccag gccaacctcc
      241 aaggcgccta atttatcagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 agtttattac tgcatgcaag gtacacacct tccattcact ttcggccccg ggaccaaact
      421 ggatatcaaa cgag
//
LOCUS       KCVT01000574             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17971:7300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000574
VERSION     KCVT01000574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17971:7300"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78099.1"
                     /translation="CQQHADSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          119 c          109 g           86 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggta
      181 ttagcaactg gttggcctgg tatcaacaga gaccagggaa agcccctaag gtcctgatct
      241 ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaacc ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tttcgcaaca tattactgtc
      361 aacagcatgc tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000575             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16938:22431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000575
VERSION     KCVT01000575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16938:22431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..364
                     /note="immunoglobulin light chain variable region"
     V_region        87..364
     V_segment       87..326
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78100.1"
                     /translation="CQQYNSDPYTF"
     J_segment       327..364
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           95 a           94 c           99 g           79 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccagga gacagagtca ccatcacttg tcgggcgagt
      121 cagggcatta gaagttattt agcgtggtat caactgagac cagggaaagc cccgaaggcc
      181 ttaatctatt acgcgaccat tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc agcctgcagc ctgaggattt tgcaacttat
      301 ttctgtcaac agtataacag tgacccgtac acttttggcc aggggaccaa agtggagatc
      361 aaacgag
//
LOCUS       KCVT01000576             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9685:11131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000576
VERSION     KCVT01000576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9685:11131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78101.1"
                     /translation="CQQYNTLITF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          109 a          111 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcgcttgccg ggcaagtcag
      181 gacataagta attatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattaca caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttatttc
      361 tgtcaacagt ataacacttt aatcactttc ggcgggggaa ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000577             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:5233:9986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000577
VERSION     KCVT01000577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:5233:9986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78102.1"
                     /translation="CQQGYRYPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          106 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg tgggagacac agtcacgatc acttgccagg cgagtcaaga
      181 cattgacatt aatttaaatt actatcaaca gaaaccaggg aaagccccta aactcctgat
      241 ctatagggca tcccgtttgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc gctctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagatacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000578             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17493:10045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000578
VERSION     KCVT01000578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17493:10045"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78103.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gctccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagaatt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000579             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8908:8526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000579
VERSION     KCVT01000579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8908:8526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78104.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          121 c          117 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cattggggac attgtgatga cccagactcc
      121 actctccccg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg ttcctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000580             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12906:14525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000580
VERSION     KCVT01000580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12906:14525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78105.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          117 c          105 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagtctggt atcagttgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000581             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12809:2758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000581
VERSION     KCVT01000581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12809:2758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78106.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgttctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01000582             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13090:14273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000582
VERSION     KCVT01000582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13090:14273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78107.1"
                     /translation="CMQALEFPYSF"
     J_segment       404..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctattgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcat ggatagtggg gatgtaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acatctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacggatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtacagt tttggccagg
      421 ggaccagagt tgagatcaaa cgag
//
LOCUS       KCVT01000583             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19301:11962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000583
VERSION     KCVT01000583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19301:11962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..374
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78108.1"
                     /translation="SMHDYGWPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          112 c          117 g           92 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtctccatct cctgccaagc cagagcagat
      181 gtacatggtg aaatatcttg gatccggata aaccttgaac aaagacttga accccattta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagaccggt tcatcagcaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 atgcatgact atgggtggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 a
//
LOCUS       KCVT01000584             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16471:15673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000584
VERSION     KCVT01000584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16471:15673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78109.1"
                     /translation="CLQGYSPPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattta cgattattta agttggtatc agcagacacc aggaaaaact cctaagcgcc
      241 tgatctatgc tgcatccagt ttgcaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtctaca gggttatagt cccccgtgga cgttcggcca agggaccaag gtggaagtca
      421 aacgag
//
LOCUS       KCVT01000585             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7345:16882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000585
VERSION     KCVT01000585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7345:16882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78110.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccagacc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000586             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10385:8180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000586
VERSION     KCVT01000586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10385:8180"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78111.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 attttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000587             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4513:12007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000587
VERSION     KCVT01000587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4513:12007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78112.1"
                     /translation="CLQGDTAPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          113 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattaacga ttatttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctaa
      241 tctatgctgc atctagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca gtttattact
      361 gtctacaggg tgatactgcc ccgttcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000588             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7194:13871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000588
VERSION     KCVT01000588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7194:13871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78113.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          113 c          114 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccgtcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcgttagaa gttatttagc gtggtatcag ctgagaccag ggaaagcccc gaaggcctta
      241 atctattacg cgaccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aggattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000589             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14470:11724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000589
VERSION     KCVT01000589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14470:11724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78114.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttcat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01000590             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7887:21888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000590
VERSION     KCVT01000590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7887:21888"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78115.1"
                     /translation="CMQPLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag cgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggtt ttattactgc atgcaacctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000591             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17373:18695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000591
VERSION     KCVT01000591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17373:18695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78116.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc atgtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccatacg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000592             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14440:17595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000592
VERSION     KCVT01000592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14440:17595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..382
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78117.1"
                     /translation="CQQRNSYPYIYSF"
     J_segment       390..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          101 a          114 c          113 g          101 t
ORIGIN      
        1 acatggggag ttagacccag tctggacgca gcatggacat cagggtcctc gctcagcttc
       61 tcgggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagttg acccagtctc
      121 cggcctccct gtctgcatct gttggagaca gggtcaccat cacttgtcgg gcaagtcagg
      181 acattggcag ttatttagcc tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataaggc gtccagtttg caaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaggctga agattttgca gtttattact
      361 gtcaacagcg taatagttac ccgtacatct acagttttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01000593             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9435:19357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000593
VERSION     KCVT01000593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9435:19357"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..403
                     /note="immunoglobulin light chain variable region"
     V_region        112..403
     V_segment       112..366
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78118.1"
                     /translation="CQQNSNWPLTF"
     J_segment       367..403
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT           98 a          120 c          108 g           80 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 ctgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagccta gcctggtacc agcagaaaac tgggcaggct
      241 cccagactcc tcatgtatgg tgcatccaac agggccactg gcatcccaga gttcactctc
      301 accatcagca gcctggagcc tgaagatgtt gcagtttatt attgtcagca gaacagtaac
      361 tggcctctca ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01000594             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12364:12508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000594
VERSION     KCVT01000594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12364:12508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78119.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          111 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagctgag accagggaaa gtcccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acaatataac agtgacccgt acacttttgg ccaggggacc aaagtagaga tcaaacgag
//
LOCUS       KCVT01000595             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12529:8925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000595
VERSION     KCVT01000595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12529:8925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78120.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          121 c          123 g          100 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ctggagagcc ggcctccgtc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tctggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgacttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgta tgcaagcact ggagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000596             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18789:4629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000596
VERSION     KCVT01000596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18789:4629"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78121.1"
                     /translation="CQQGYNTPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          117 c          118 g           90 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattagc agctggttag cctggtatca gcagaaacca gggcaagccc ctaatctcct
      241 gatctataag gcgtccagtt tggcaagtgg ggtcccatca aggttcagcg gcggtggatc
      301 tgggacggat tacactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag ggttacaata ccccgtggac gttcggccaa gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000597             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14239:2772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000597
VERSION     KCVT01000597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14239:2772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78122.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          126 c          115 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcagttcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01000598             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:5420:17824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000598
VERSION     KCVT01000598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:5420:17824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78123.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcaaagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01000599             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21740:4985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000599
VERSION     KCVT01000599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21740:4985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78124.1"
                     /translation="CMQALEFPYSF"
     J_segment       400..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgacttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tacagttttg gccaggggac
      421 cgaagtggag atcaaacgag
//
LOCUS       KCVT01000600             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12296:16364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000600
VERSION     KCVT01000600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12296:16364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78125.1"
                     /translation="CQQHDNAPWTF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          109 a          117 c          118 g           85 t
ORIGIN      
        1 acatgggggg caggagtcag tctcagacag gacacagcat ggacacgagg gtccccgctc
       61 agctcctggg gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc
      121 agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca
      181 gtcagagtat taacgactgg ttggcctggt atcaacagag accagggaag gcccctaagc
      241 tcctgatcta tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg
      301 gatctgggac agatttcact ctcagcatca gcagcctgca gcctgaagat atcgcaacat
      361 attactgtca gcagcatgac aatgccccgt ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01000601             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22803:8420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000601
VERSION     KCVT01000601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22803:8420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78126.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccag cacaaacctg ggcaggctcc caagctcctc
      241 ctctatggtg catccaccag ggcctccggc atcccaggca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000602             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19280:15617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000602
VERSION     KCVT01000602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19280:15617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78127.1"
                     /translation="CMQALDFPLAF"
     J_segment       406..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          122 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcgctttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000603             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12889:8617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000603
VERSION     KCVT01000603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12889:8617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78128.1"
                     /translation="CQQDYHWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          124 c          109 g           86 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag acatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaacc tctcctgcag ggccagtcag
      181 agtgttggca gcaccttaac ctggtaccac cagaagcctg ggcaggctcc caagctcctc
      241 atctatggtc catccatccg ggccagcggc atcccagaca aattcagtgg cagtgggtct
      301 ggaacagaat ttactctcac catcagcagc ctggagactg aagatgttgg agtttattac
      361 tgtcagcagg attatcactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000604             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16411:15909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000604
VERSION     KCVT01000604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16411:15909"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78129.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          105 t
ORIGIN      
        1 acagggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactaatttc acactgagaa tcagtagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000605             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8676:11088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000605
VERSION     KCVT01000605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8676:11088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78130.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          124 c          116 g           86 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccaacaaaaa cctgggcagg ctcccaggct
      241 cctcatctat ggtgcatcca gcagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gacttcactc tcaccatcac cagcctggag cctgaagatg ttgcagttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000606             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23170:13870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000606
VERSION     KCVT01000606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23170:13870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78131.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT           97 a          123 c          114 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaggctcc
      241 ttgtccatag tacattcttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 agcgag
//
LOCUS       KCVT01000607             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16976:13101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000607
VERSION     KCVT01000607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16976:13101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78132.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          108 c          107 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctaa
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggagagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000608             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20193:15896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000608
VERSION     KCVT01000608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20193:15896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..364
                     /note="immunoglobulin light chain variable region"
     V_region        87..364
     V_segment       87..326
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78133.1"
                     /translation="CQQYNSDPRTF"
     J_segment       330..364
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           92 a           98 c          101 g           76 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccagga gacagagtca ccatcacttg tcgggcgagt
      121 cagggcattc gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaagccc
      181 ttgatctatt acgcgtccac tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      301 tactgtcaac agtataacag tgacccgcgc actttcggtg gagggaccaa ggtggagatc
      361 aaacgag
//
LOCUS       KCVT01000609             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9343:13294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000609
VERSION     KCVT01000609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9343:13294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78134.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          119 c          117 g           89 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcactag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttgggt ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000610             291 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:3359:9764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000610
VERSION     KCVT01000610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 291)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:3359:9764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..251
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <228..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78135.1"
                     /translation="CMQALDFPYSF"
     J_segment       252..288
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>291
                     /gene="IGKC"
BASE COUNT           72 a           65 c           81 g           73 t
ORIGIN      
        1 acatgggcat ctcctgcagg tctagtcaga gcctcttgga tagtgaggat ggaaacacct
       61 atttggaatg gtacctacag aagccaggcc agtctccaca gctcttgatt tttgaggttt
      121 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actaatttca
      181 cactgaaaat cagcagtgtg gaggctgagg atgttggggt ctattactgc atgcaagctc
      241 tagactttcc ttacagtttt ggccagggga ccacagtgga gattaaacga g
//
LOCUS       KCVT01000611             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15549:3078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000611
VERSION     KCVT01000611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15549:3078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78136.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           93 a          122 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgagctt tccagccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgagaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01000612             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5874:16650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000612
VERSION     KCVT01000612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5874:16650"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..371
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78137.1"
                     /translation="CQQHNNYSPTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          106 a          119 c          105 g           91 t
ORIGIN      
        1 atggggagtc agaaccactc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 ccctccctgt ctgcatctgt aggagacaca gtcaccatca cttgtcgggc aagtcagggc
      181 attagcaatg atttagcctg gtatcagctg aaaccaggga aagccccgaa gcccctgatc
      241 tattacgcat ccaatttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacaacata ataattactc tcccactttc ggcggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000613             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16781:14743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000613
VERSION     KCVT01000613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16781:14743"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78138.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaccccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctatccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000614             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12285:14155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000614
VERSION     KCVT01000614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12285:14155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..421
                     /note="immunoglobulin light chain variable region"
     V_region        85..421
     V_segment       85..383
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78139.1"
                     /translation="CGQGTHLPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           91 a          123 c          118 g           92 t
ORIGIN      
        1 acatggggga ctcctcagtt caccatgagg ctccctgctc agctcctggg gctgctattg
       61 ctctgcgtcc ccggatccac tggggatgtt gtgatgactc agtctccgct ctccctgccc
      121 atcacccctg gacagccggc ctccgtctcc tgcaggtcta gtcaaagcct tgtgcacagc
      181 gatggaaaca catacttgac ttggtatcaa cagaagccag gccaacctcc aaggcgccta
      241 atttttgagg tttctaaccg ggactctggg gtcccagaca gattcagcgg cagtggggca
      301 gggacagatt tcacactgaa aatcagcaga gtggaggctg acgatgttgg ggtttattac
      361 tgcggccaag gtacacacct tccgtggacg ttcggccaag ggaccacggt ggaactcaaa
      421 cgag
//
LOCUS       KCVT01000615             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23272:10190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000615
VERSION     KCVT01000615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23272:10190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78140.1"
                     /translation="CLQGYSAPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          107 g           99 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgctt cggtaggaga cagaatcacc atcacttgtc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaaactc ctcagcgcct
      241 gatttatgct acatccagtt tggaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggttatagtg ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01000616             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13345:12199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000616
VERSION     KCVT01000616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13345:12199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78141.1"
                     /translation="CIQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccaaaatc
      121 cattttccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatggagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tacagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000617             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17096:4546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000617
VERSION     KCVT01000617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17096:4546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78142.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          109 c          111 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattgagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcgttaacg tttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagcccctg
      241 atcttttatg caaaccgttt ggaacgtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aagttattat
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000618             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10996:16401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000618
VERSION     KCVT01000618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10996:16401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..394
                     /note="immunoglobulin light chain variable region"
     V_region        74..394
     V_segment       74..357
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78143.1"
                     /translation="CQQNSNWPLTF"
     J_segment       358..394
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           91 a          123 c          104 g           79 t
ORIGIN      
        1 acatggggaa ccatggaagc cccagcacag cttctcttcc tcccgctgct ctggctccca
       61 gataccaccg gacaaatagt gctgacgcag tctccagcca ccctgtcctt gtctccagga
      121 gaaagagcca ccctctcctg cagggccagt cagagtgtca gcagcagcct agcctggtac
      181 cagcagaaac ctgggcaggc tcccagactc ctcatctttg gtgcatccaa cagggccact
      241 ggcatcccag gcaggttcag tggcagtggg tctgggacag agttcactct caccatcagc
      301 agcctggagc ctgaagatgt tgcactttat tattgtcagc agaacagtaa ctggcctctc
      361 actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01000619             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14603:16433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000619
VERSION     KCVT01000619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14603:16433"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78144.1"
                     /translation="CMQGTHLPFTF"
     J_segment       390..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          100 a          119 c          109 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccaatggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtctatca ctcttggaca accggcctcc atttcctgca ggtctagtca cacccttgta
      181 cacagtgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggagtt
      361 tattactgca tgcaaggtac acaccttcca ttcactttcg gccccgggac caaactggat
      421 atcaaacgag
//
LOCUS       KCVT01000620             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13231:16593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000620
VERSION     KCVT01000620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13231:16593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78145.1"
                     /translation="CMQALEFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggcacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cctacagttt tggccagggg
      421 accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01000621             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15658:8247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000621
VERSION     KCVT01000621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15658:8247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78146.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcatc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000622             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18775:14577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000622
VERSION     KCVT01000622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18775:14577"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78147.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          118 c          119 g          110 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacttgcaga aggcaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagcca ctgatttcaa actgaacatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000623             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14753:18095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000623
VERSION     KCVT01000623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14753:18095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78148.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000624             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:8883:7805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000624
VERSION     KCVT01000624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:8883:7805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78149.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          111 g          111 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aagctccctg ctcagctcct
       61 ggggctgcta atgctctggc tctctggttc cagtggggat gttgtgatga cccagactcc
      121 attctccctg tccgttagcc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttgaat agtgaagacg gaaacaccta tttggattgg tacctgcaga ggccgggcca
      241 gtctccacag cccttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttgggatt tatatctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01000625             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16353:9564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000625
VERSION     KCVT01000625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16353:9564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78150.1"
                     /translation="CQQYNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          118 c          108 g           93 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataataatt attctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000626             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17750:9713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000626
VERSION     KCVT01000626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17750:9713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..281
                     /note="immunoglobulin light chain variable region"
     V_region        5..281
     V_segment       5..239
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78151.1"
                     /translation="CQQYDSDPFTF"
     J_segment       246..281
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>284
                     /gene="IGKC"
BASE COUNT           74 a           70 c           77 g           63 t
ORIGIN      
        1 acatggggac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca gttatttagc
       61 gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg cgtccacttt
      121 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      181 catcagcagc ctgcagcctg aagattttgc aacctattac tgtcaacagt atgacagtga
      241 tccgttcact ttcggtgggg ggaccaaggt agacatcaaa cgag
//
LOCUS       KCVT01000627             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:21054:11207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000627
VERSION     KCVT01000627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21054:11207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78152.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          111 g          111 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aagctccctg ctcagctcct
       61 ggggctgcta atgctctggc tctctggttc cagtggggat gttgtgatga cccagactcc
      121 attctccctg tccgttagcc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttgaat agtgaagacg gaaacaccta tttggattgg tacctgcaga ggccgggcca
      241 gtctccacag cccttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttgggatt tatatctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01000628             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13793:10220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000628
VERSION     KCVT01000628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13793:10220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78153.1"
                     /translation="CQKYSSFPFSF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          122 c          111 g           94 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaacaccgg acaagttata ttgactcagt
      121 ctccagccac tctgtctttg tctccggggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccagactcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagaa gtatagtagt ttcccattca gtttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01000629             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17017:12224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000629
VERSION     KCVT01000629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17017:12224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78154.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          109 c          109 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcaac agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000630             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20265:9997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000630
VERSION     KCVT01000630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20265:9997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78155.1"
                     /translation="CLQYKSFPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          109 c          109 g          106 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtggg agacactgtc accatcactt gccgggcaag
      181 tcaggatatt aacagttatt taaattggtt tcagctgaaa ccagggaaag ccccaaaggt
      241 cctgatctat gctgcatcca gtttggaaag tggggtcccg tctaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag tagcctgcag cctgaagatt ttgcaactta
      361 ttattgtcta cagtataaaa gttttcctct cactttcggt ggagggacca aggtggatat
      421 caaacgag
//
LOCUS       KCVT01000631             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13337:2328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000631
VERSION     KCVT01000631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13337:2328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78156.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aattctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01000632             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15177:19569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000632
VERSION     KCVT01000632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15177:19569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..368
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78157.1"
                     /translation="CQQGYYTPFTF"
     J_segment       383..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT           96 a          120 c          109 g           98 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg cccgatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat ctcttgccga gccagtcagg
      181 gtattagcag ctggttagcc tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataaggc gtccagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatttg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgct acttattttt
      361 gtcaacaggg ttactatacc ccattcactt tcggccccgg gaccaaactg gatatcaatc
      421 gag
//
LOCUS       KCVT01000633             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:6326:19305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000633
VERSION     KCVT01000633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6326:19305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78158.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          112 c          102 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctacttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acgttaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000634             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:25464:8326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000634
VERSION     KCVT01000634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25464:8326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78159.1"
                     /translation="CQQCDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tgtgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000635             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22964:17866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000635
VERSION     KCVT01000635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22964:17866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78160.1"
                     /translation="CMQSLEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctggccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctct agagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000636             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6627:18356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000636
VERSION     KCVT01000636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6627:18356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78161.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgctgg tctagtcgga
      181 gcctcttgga tagtgaagat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactggaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000637             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24736:22263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000637
VERSION     KCVT01000637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24736:22263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..427
                     /note="immunoglobulin light chain variable region"
     V_region        96..427
     V_segment       96..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78162.1"
                     /translation="TVCRVNSPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca atggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcgt ctgcagagcc agtgagagtg
      181 tcaatgtctt tggaataaac ctcattcact ggtatcagca gaaaccagga caacctccta
      241 aacccctgat ttaccaagca tccaataaag aaactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaagctgac gatgctgcag
      361 attattactg tctgcagagt aaattctccg tggacgtttg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01000638             554 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16291:18662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000638
VERSION     KCVT01000638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 554)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16291:18662"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    230..551
                     /note="immunoglobulin light chain variable region"
     V_region        230..551
     V_segment       230..505
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <491..>523
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78163.1"
                     /translation="CQQGYTYLYSF"
     J_segment       513..551
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        552..>554
                     /gene="IGKC"
BASE COUNT          125 a          157 c          137 g          135 t
ORIGIN      
        1 acatgggggc tgagttgctg agatgagcca gccctgcagc tgtgctcagt ctgtcccatc
       61 ccctgctgat ttgcatgttc ccagagcaca accctctgcc ccgaagactt ttttataggc
      121 tggtcacacc ctgtgcagga gtcagtctca gtcaggacac agcatggaca tgagggtccc
      181 cgctcagctc cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat
      241 gacgcagtct ccatcctccc tgtccgcatc tgttggagac acagtcacca tcacttgcca
      301 ggcgagtcaa gccattgcca ataatttaaa ttggtatcag cagaaaccag gaaaagcccc
      361 taaagtcctg atctataggg catccagttt gcaaagtggg tttccctctc ggttcagcgg
      421 cagtggatct gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc
      481 cacttattac tgtcaacagg gttatactta cttgtacagt tttggccagg ggaccaaagt
      541 ggagatcaaa cgag
//
LOCUS       KCVT01000639             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17897:3250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000639
VERSION     KCVT01000639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17897:3250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78164.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          122 c          118 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000640             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18321:15112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000640
VERSION     KCVT01000640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18321:15112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78165.1"
                     /translation="CIQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtgtc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtctgaca tcgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca ttcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000641             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22556:4740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000641
VERSION     KCVT01000641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22556:4740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..282
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78166.1"
                     /translation="CMQALEFPWTF"
     J_segment       283..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           73 a           81 c           88 g           80 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      241 gatgttggta tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000642             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19040:17061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000642
VERSION     KCVT01000642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19040:17061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..269
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78167.1"
                     /translation="CQQHNTYPYTF"
     J_segment       270..307
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>310
                     /gene="IGKC"
BASE COUNT           85 a           80 c           73 g           72 t
ORIGIN      
        1 acatgggcat cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca
       61 agtcaggaca ttagtaatga tttagcctgg tatcagcaga aaccagggaa agccccaaag
      121 cccctgatct tttacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt
      181 ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact
      241 tattactgtc aacagcataa tacttacccg tacacttttg gccaggggac caaggtggag
      301 atcaaacgag
//
LOCUS       KCVT01000643             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18829:15640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000643
VERSION     KCVT01000643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18829:15640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78168.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          122 c          121 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgagat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttgcact ggtacctgca gaagccaggc
      241 cagtctccac agctcttaat ttacgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000644             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19848:6591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000644
VERSION     KCVT01000644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19848:6591"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78169.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          123 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagttta gtctggtacc agcagaagcc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000645             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9826:7202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000645
VERSION     KCVT01000645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9826:7202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78170.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g           93 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcaccaga agccaggcca acctccaagg
      241 cgcctaattt ctgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac gctgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01000646             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20800:9396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000646
VERSION     KCVT01000646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20800:9396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..235
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <212..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78171.1"
                     /translation="CMQALEFPWTF"
     J_segment       236..272
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>275
                     /gene="IGKC"
BASE COUNT           70 a           59 c           81 g           65 t
ORIGIN      
        1 acatgggagt cagagcctct tggatagtga ggatggaaac acctatttgg attggtacct
       61 gcagaagcca ggccagtctc cacacctctt gatttatgag gtttccaacc gggcctctgg
      121 agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag
      181 agtggaggct gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccttggac
      241 gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000647             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20230:8208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000647
VERSION     KCVT01000647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20230:8208"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78172.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          114 c          111 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ccggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000648             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11935:10518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000648
VERSION     KCVT01000648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11935:10518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78173.1"
                     /translation="CMQGLEFPRTF"
     J_segment       405..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggt gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca gatctagtca
      181 gagtctcttg gatagtgcgg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca catctcttga tttatgaggt ctccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtggctcag acactgattt cacactaaag atcagtagag tggaggctga
      361 ggatgttggg gtctattact gcatgcaagg tctagagttt cctcggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000649             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15021:9836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000649
VERSION     KCVT01000649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15021:9836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..374
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78174.1"
                     /translation="SMHDYGWPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          111 c          117 g           93 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtctccatct cctgccaagc cagagcagat
      181 gtacatggtg aaatatcttg gatccggata aaccttgaac aaagacttga accccattta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagaccggt tcatcagtaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 atgcatgact atgggtggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 a
//
LOCUS       KCVT01000650             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5931:6182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000650
VERSION     KCVT01000650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5931:6182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78175.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcccccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000651             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21478:12739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000651
VERSION     KCVT01000651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21478:12739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78176.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaggtggag atcaaacgag
//
LOCUS       KCVT01000652             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14008:17655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000652
VERSION     KCVT01000652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14008:17655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78177.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggcctctg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000653             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19025:12898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000653
VERSION     KCVT01000653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19025:12898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78178.1"
                     /translation="CYQHSRGWAF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           97 a          122 c          117 g           82 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaaa ttatattgac acagtctcca
      121 gccaccctgt ctttggcacc aggggaaaga gccactctct cctgcagggc cagtgagaat
      181 gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag gctcctcgtc
      241 cacagtgcgt ccagcagggc cactgacatc ccagacaggt tcagtggcag tgggtctcgg
      301 acagagttca ccctcaccag cagcagtctg gagcctgaag atgttggagt ctattactgc
      361 tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01000654             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24397:21702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000654
VERSION     KCVT01000654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24397:21702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78179.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaactcc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatacggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000655             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12046:13799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000655
VERSION     KCVT01000655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12046:13799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78180.1"
                     /translation="CQQGYNTPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          114 c          118 g           91 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcgtc cctgtctgca tctgtaggag acaaagtcac catcacttgc cgagccagtc
      181 aggatattag cagctggtta gcctggtatc agctgaagcc ggggaaagcc cctaaactct
      241 tgatctataa ggcgtccagt ttggcaagag gggtcccatc gaggttcagc ggcagtggat
      301 ctgggacgga ttacactctc accatcagta gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gggttacaat accccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000656             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11340:6525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000656
VERSION     KCVT01000656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11340:6525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..381
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78181.1"
                     /translation="CQQVYSNPAF"
     J_segment       384..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          111 c          108 g           99 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccctg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgat atccaggtga cccagtctcc
      121 atctgccttg tctgcatctg taggagacag agtcaccatc tcttgccggg caagtcagaa
      181 catttatagg aatttagcgt ggtatcagca gaaaccaggg aaagccccta agctcctgat
      241 ctttgctgca tccagattgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcaacct acagcctgaa gattctgcaa tttattactg
      361 tcaacaggtt tatagtaacc cggcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000657             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13146:20478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000657
VERSION     KCVT01000657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13146:20478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..312
                     /note="immunoglobulin light chain variable region"
     V_region        152..312
     V_segment       152..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78182.1"
                     /translation="CMQALEFPWTF"
     J_segment       275..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           87 c           89 g           70 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatcttg
      241 gggtttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01000658             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13704:14327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000658
VERSION     KCVT01000658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13704:14327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78183.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          118 c          119 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac tctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagagacc tgggcagact cacaaactcc
      241 tcgtttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000659             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17576:15481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000659
VERSION     KCVT01000659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17576:15481"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78184.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccagggca
      241 gtctccacaa ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggactttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01000660             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24954:17098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000660
VERSION     KCVT01000660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24954:17098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78185.1"
                     /translation="CQQYNSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          113 a          114 c          106 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcgagtc
      181 agggcattag aagttattta gcgtggtatc agcagaaacc aggaaaagcc ccgaaggcct
      241 tgatctatta cgcatccatt ttagaaaatg cggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctacagtc tgacgatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01000661             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:8625:6194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000661
VERSION     KCVT01000661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8625:6194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..395
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78186.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg ctagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaagtt tccaagcggt cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagtagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagacttcc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000662             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21938:3647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000662
VERSION     KCVT01000662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21938:3647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78187.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          116 c          104 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc caaatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgtatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca ccagcctgca gcctgaagat tttgcaagtt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000663             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10185:20521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000663
VERSION     KCVT01000663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10185:20521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..335
                     /note="immunoglobulin light chain variable region"
     V_region        14..335
     V_segment       14..295
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <275..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78188.1"
                     /translation="CLQESNWSYSF"
     J_segment       298..335
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>338
                     /gene="IGKC"
BASE COUNT           80 a           92 c           98 g           68 t
ORIGIN      
        1 acatgggacc ggagaaatag tggtgacaca gtctccagcc accctgtctt tgtctccagg
       61 ggaaagagcc accctctcct gcagggccag tcagagtgtc aaaagcaggt tagcctggta
      121 ccagcagaaa cctgggcaag ctcccaggct cctcatgtat gatgcgtcca gcagggccac
      181 tggcatccca gacaggttca ctggcagcgg gtctgggcca gagttcactc tcaccatcag
      241 cagcctggag cctgaagatg ttgcggttta tttctgtctt caggagagta actggtcgta
      301 cagctttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01000664             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22237:3971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000664
VERSION     KCVT01000664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22237:3971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..367
                     /note="immunoglobulin light chain variable region"
     V_region        28..367
     V_segment       28..329
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <307..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78189.1"
                     /translation="CMQPLEFPWTF"
     J_segment       330..367
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           84 a           93 c          108 g           85 t
ORIGIN      
        1 acatgggggc tccctggatc cagtggggac attgtgatga cccagactcc actgtccctg
       61 cccgtcaccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag cctcttggat
      121 agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca gtctccacag
      181 ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt cagtggcagt
      241 gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      301 tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac caaggtggaa
      361 atcaaacgag
//
LOCUS       KCVT01000665             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18630:18259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000665
VERSION     KCVT01000665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18630:18259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78190.1"
                     /translation="CQQYNSEPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           91 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcacagt tatttagcgt ggtatcagca gaaaccaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgagc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000666             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:11652:4041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000666
VERSION     KCVT01000666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11652:4041"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78191.1"
                     /translation="CLQGYITPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          113 c          109 g           99 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctac atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg gcttattact
      361 gtctacaggg ttatattacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000667             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12454:11362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000667
VERSION     KCVT01000667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12454:11362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78192.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          118 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtcttcaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacagtctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000668             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7484:4880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000668
VERSION     KCVT01000668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7484:4880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78193.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000669             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23530:10542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000669
VERSION     KCVT01000669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23530:10542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78194.1"
                     /translation="CQQHNGYPPTF"
     J_segment       367..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          101 a          113 c          102 g           88 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattacga atgatttagc
      181 ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg atctattacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattat tgtcaacagc ataatggata
      361 ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01000670             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14297:5002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000670
VERSION     KCVT01000670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14297:5002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78195.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          121 c          117 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctctcaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000671             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9698:16001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000671
VERSION     KCVT01000671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9698:16001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78196.1"
                     /translation="CQQYNSDPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          112 c          110 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccaggtgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttagaagtta tttagcgtgg tatcaactga gaccagggaa agccccgaag gccttaatct
      241 attacgcgac cattttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgagga ttttgcaact tatttctgtc
      361 aacagtataa cagtgacccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000672             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7184:14276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000672
VERSION     KCVT01000672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7184:14276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78197.1"
                     /translation="CMQDIQLPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           85 a          124 c          124 g          106 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattgtgct gactcagact
      121 ccactctccc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc atagtaatgg atacacctat ttgttttggt acctgcagag gccaggccag
      241 tctccacaac ttctggtcta tttgggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgcaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgcat gcaagatata cagcttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000673             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6232:4345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000673
VERSION     KCVT01000673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6232:4345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78198.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          105 a          125 c          112 g           85 t
ORIGIN      
        1 aacatggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcaacagctt agcctggtac caacaaaaac ctgggcagcc tcccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag aggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01000674             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13923:17454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000674
VERSION     KCVT01000674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13923:17454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78199.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagcgc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000675             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11302:17002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000675
VERSION     KCVT01000675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11302:17002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78200.1"
                     /translation="CQQYDSDSLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          108 a          121 c          118 g           99 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtctg
      181 catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtatgacagt gattcgctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01000676             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12936:11786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000676
VERSION     KCVT01000676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12936:11786"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78201.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatacggg cctctggagt cccagacagg
      301 ttcagtggca ttgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000677             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22886:5647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000677
VERSION     KCVT01000677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22886:5647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..235
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <212..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78202.1"
                     /translation="CMQALEFPLTF"
     J_segment       236..272
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>275
                     /gene="IGKC"
BASE COUNT           68 a           57 c           82 g           68 t
ORIGIN      
        1 acatgggagt cagagcctct tggatagtgg ggatggaaac acctatttgg attggtacct
       61 gcagaagcca ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg
      121 agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga aaattaacag
      181 agtggaggct gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctcac
      241 tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000678             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25922:8399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000678
VERSION     KCVT01000678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25922:8399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78203.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gctttattac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000679             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13159:12550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000679
VERSION     KCVT01000679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13159:12550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78204.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           97 a          117 c          117 g          100 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcac tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccttcacc tgcagagcca gtgggagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 actcctgatt tatcaagcaa gcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaacctgacg atgctgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01000680             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24231:6170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000680
VERSION     KCVT01000680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24231:6170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..349
                     /note="immunoglobulin light chain variable region"
     V_region        149..349
     V_segment       149..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78205.1"
                     /translation="CMQPLEFPWTF"
     J_segment       312..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           76 a           97 c           98 g           81 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccac agctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaacct
      301 ctagagtttc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000681             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20334:9001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000681
VERSION     KCVT01000681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20334:9001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78206.1"
                     /translation="CQHGYGIPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagtccc agtcaggaca cagcatggac atgagggccc ccactcagct
       61 cctggggttc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc aggcgagtca
      181 ggccattagt aataatgtaa tctggtatca gcaggaaccg gggaaagccc ctaagctcct
      241 gatctataag gcatccactt tacaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcagcat ggttatggta tcccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000682             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:19201:7622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000682
VERSION     KCVT01000682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19201:7622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78207.1"
                     /translation="CQQYNSLPYIF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          110 a          109 c          104 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaacgttta tttaaattgg tatcagcaga aaccggggaa agcccctaaa cccctgatct
      241 attatagaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcaact tattactgtc
      361 aacagtataa tagtttaccg tacatttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000683             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5944:13707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000683
VERSION     KCVT01000683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5944:13707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78208.1"
                     /translation="CLQGDTAPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg aatcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggcaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcattaac gattatttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggtgatactg ccccgttcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000684             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:9712:11449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000684
VERSION     KCVT01000684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9712:11449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78209.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tcgagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatgtca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000685             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13678:8018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000685
VERSION     KCVT01000685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13678:8018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78210.1"
                     /translation="CQQYNSDPRTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          118 c          109 g           91 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aacccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtata acagtgaccc gcgcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000686             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8169:13336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000686
VERSION     KCVT01000686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8169:13336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78211.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc caagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000687             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5970:10404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000687
VERSION     KCVT01000687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5970:10404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78212.1"
                     /translation="CQQYNSLPWTF"
     J_segment       379..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          109 a          108 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtagttat ttaaattggt atcaacagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcaacctgca acctgaggat tttgcaagtt attactgtca
      361 acagtataat agtttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01000688             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8690:15593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000688
VERSION     KCVT01000688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8690:15593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78213.1"
                     /translation="CMQALQTPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          116 c          119 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgtct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcacc cttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgaa tagtaatgga tacaactatt tgaattggta cctgcagaag ccaggccagt
      241 ctccacatct tctgatctat tatggttcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgaaaatcag cagggtggag gctggggacg
      361 taggggttta ttactgcatg caagctctac aaactccgta cagttttggc caggggacca
      421 gagtggagat caaacgag
//
LOCUS       KCVT01000689             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:25139:15127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000689
VERSION     KCVT01000689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25139:15127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78214.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          113 c          105 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tgacagttct ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agtttggcaa gtggggtccc atcaaggttc agcggcagtg gatctgggcc
      301 agatttcact ctcattatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtacaaa agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000690             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23275:13695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000690
VERSION     KCVT01000690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23275:13695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78215.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tttcctgcag gtcaagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttgcact ggtacttgaa gaagccaggc
      241 cagtctccac aggtcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000691             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24362:12162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000691
VERSION     KCVT01000691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24362:12162"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78216.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggaa
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000692             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5449:10221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000692
VERSION     KCVT01000692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5449:10221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78217.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacctt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01000693             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22572:5848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000693
VERSION     KCVT01000693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22572:5848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78218.1"
                     /translation="CEQYNSLPYTF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          109 a          110 c          102 g           96 t
ORIGIN      
        1 atggggagac ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctggggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct
      121 ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacgtta
      181 acatttattt aaattggtat caccagaaac cggggaaagc ccctaagctc ctgatctatt
      241 atacaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat tactgtgaac
      361 aatacaatag tttaccgtac acttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01000694             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22757:4375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000694
VERSION     KCVT01000694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22757:4375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78219.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000695             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9708:17244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000695
VERSION     KCVT01000695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9708:17244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78220.1"
                     /translation="CMQGLEFPITF"
     J_segment       401..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          122 c          118 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata ctgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgatgtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacgc tgatttcaca ctgagaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaaggtcta gagtttccaa tcactttcgg ccccgggacc
      421 aaactggaga tcaaacgag
//
LOCUS       KCVT01000696             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20916:8538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000696
VERSION     KCVT01000696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20916:8538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78221.1"
                     /translation="CQQYDKSPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          118 c          115 g           86 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gggtcaccat cacttgcaga gccagtcagg
      181 gtatcagcaa ctggttggcc tggtatcaac agaaaccagg gagagcccct aacctcctga
      241 tgtatagggc gtccaatttg caaggagggg tcccatcaag gttcagagga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga ggatgtcgct acatattact
      361 gtcaacagta tgataagtcc cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000697             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18408:15011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000697
VERSION     KCVT01000697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18408:15011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78222.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagaatc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01000698             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16744:11845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000698
VERSION     KCVT01000698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16744:11845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..440
                     /note="immunoglobulin light chain variable region"
     V_region        104..440
     V_segment       104..402
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78223.1"
                     /translation="CLQDIQLPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           89 a          124 c          122 g          108 t
ORIGIN      
        1 acatggggtg actgatcagg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctgggg ctgctggtgc tctggctccc tgggaccagt ggggatatta tgatgactca
      121 gactccactc tccctgtccg tcacccctgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ctgcatagga atgggtacac ctatttgttt tggtacctgc agaagccagg
      241 ccagtctcca cagctcctga tctatttcgg ttccaaccgg gcctctggag tcccagacag
      301 gttcagtgcc agtgggtcag gcactgattt cacactgaaa atcagccggg tggaggctga
      361 ggatgttggg gtttattact gcttgcaaga tatacaactt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000699             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9734:17688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000699
VERSION     KCVT01000699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9734:17688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    167..321
                     /note="immunoglobulin light chain variable region"
     V_region        167..321
     V_segment       167..280
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <263..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78224.1"
                     /translation="CQQSYRYPLTF"
     J_segment       286..321
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>326
                     /gene="IGKC"
BASE COUNT           70 a           93 c           90 g           73 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcaggagtg gggtcccatc
      181 agggttcagc ggcagtggat ctgggacaga tttcactctc gccatcagca gcctgcagcc
      241 tgaagatgct gcaacttatt actgtcagca gagttatcgt tatccgctca ctttcggtgg
      301 agggacccag gtggaaatca atcgag
//
LOCUS       KCVT01000700             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:7164:12518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000700
VERSION     KCVT01000700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7164:12518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78225.1"
                     /translation="CMQALEFPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgtttggtt ttattattgc atgcaagctc tagagtttcc tcccactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000701             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9670:15190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000701
VERSION     KCVT01000701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9670:15190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78226.1"
                     /translation="CMQGTQLPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           93 a          122 c          120 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tggggctact ggtgctctgg ctccctggga ccagtggaga tattgtgatg acccagactc
      121 cactctccct acccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccttca tagtgatgga tccacctatt tggactggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatctat ttgggttcca aacgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag tcgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caaggtacac agcttccgta cagttttggc caggggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01000702             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11503:15831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000702
VERSION     KCVT01000702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11503:15831"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..387
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78227.1"
                     /translation="CQQYDDYPWTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT          105 a          114 c          115 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacaaagtc accatcactt gtcatgccag
      181 tcagggtatt agtagtcggt tagtctggta tcagcagaaa gcagggaaag cccctaagcc
      241 cctgatgtat gatgcatcca gtttacacag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggacg gattacactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa caatatgatg attacccgtg gacgttcggc caagggacca aggtggaaat
      421 caagcgag
//
LOCUS       KCVT01000703             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15708:2081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000703
VERSION     KCVT01000703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15708:2081"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78228.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctgg ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01000704             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10027:14198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000704
VERSION     KCVT01000704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10027:14198"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78229.1"
                     /translation="CMQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           86 a          124 c          122 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgctg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagagg ccaggccagt
      241 ctccacaact tctggtctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caagatatac agcttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000705             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:5195:10945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000705
VERSION     KCVT01000705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:5195:10945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78230.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          116 c          108 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gctagtcagg
      181 acattagtaa ttttttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg ggaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgcg acttatcatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000706             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20165:4197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000706
VERSION     KCVT01000706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20165:4197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78231.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccatacg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000707             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13033:7770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000707
VERSION     KCVT01000707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13033:7770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78232.1"
                     /translation="CMQSLEIPPTF"
     J_segment       406..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           93 a          122 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgggg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccacccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggc gtttattact gcatgcaatc tctagagatt cctcccactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000708             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14920:11952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000708
VERSION     KCVT01000708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14920:11952"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..396
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78233.1"
                     /translation="CMQSIKDPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          121 c          109 g          106 t
ORIGIN      
        1 acatggggat caggactcct cagttcatct tctcacgatg agactccctg ctcagctcct
       61 cgggctgttg atgctctggg tccctggatc cagtggggat attgtgatga cccagacccc
      121 actctcggtg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 ccttctccat agtaatggag acacctattt acattggtac cttcagaggt caggccagtc
      241 tccacggctc ctgatctata aagtaaccaa tcggctacct ggggtcccag acaggttcag
      301 tggcagtggg tcaggcacag atttcacact gaaaatcagc agggtggagc ctgaggatat
      361 tggtgtttat ttctgcatgc aaagtataaa agatccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01000709             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22710:12245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000709
VERSION     KCVT01000709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22710:12245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78234.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atacctccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctctgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg aggcaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000710             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22485:17630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000710
VERSION     KCVT01000710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22485:17630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78235.1"
                     /translation="CMQALEFPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           94 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccagt
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggttc ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg acgtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000711             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:9595:20254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000711
VERSION     KCVT01000711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9595:20254"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78236.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000712             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16878:13251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000712
VERSION     KCVT01000712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16878:13251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78237.1"
                     /translation="CLQDLQFPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           85 a          120 c          120 g          113 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga ttttgtgatg actcagactc
      121 cattctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgtc tagtaatgga aaaacctctt tgttttggta cctacagagg ccaggccagt
      241 ctcctcagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggaattta tttctgcttg caagatctac agtttcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000713             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:2803:8361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000713
VERSION     KCVT01000713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2803:8361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78238.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaagatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000714             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14644:15543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000714
VERSION     KCVT01000714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14644:15543"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..392
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78239.1"
                     /translation="CLQSKNSPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          103 a          115 c          115 g          100 t
ORIGIN      
        1 acatgggggg agcagcctct agttcagctc tcagaaatgg ggtcctgggc tcctttcctg
       61 tggatcctcc tgctctgtgc tccaggctgc aatggggaca ttgtgctgac ccagtctcca
      121 gcctctttgg ccgtgtctcc agggcagagg gccaccatcg tctgcagagc cagtgagagt
      181 gtcaatgtct ttggaataaa cctcattcac tggtatcagc agaaaccagg acaacctcct
      241 aaacccctga tttaccaagc atccaataaa gaaactgggg tcccagccag gttcagcggc
      301 agtgggtctg ggaccgattt caccctcaca attaatcctg tggaagctga cgatgctgca
      361 gattattact gtctgcagag taagaattct ccgtggacgt ttggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000715             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6772:12112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000715
VERSION     KCVT01000715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6772:12112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78240.1"
                     /translation="YIQTLEFPWTF"
     J_segment       275..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           73 a           79 c           86 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagtctc
      121 cacaactctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc tgacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctacattcaa actctagagt ttccgtggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01000716             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17840:5901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000716
VERSION     KCVT01000716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17840:5901"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78241.1"
                     /translation="CQQYNSDLFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          113 c          113 g           96 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tttgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccatt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gacctgttca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000717             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24176:4618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000717
VERSION     KCVT01000717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24176:4618"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78242.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt agccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01000718             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23851:14615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000718
VERSION     KCVT01000718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23851:14615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..438
                     /note="immunoglobulin light chain variable region"
     V_region        101..438
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78243.1"
                     /translation="CMQSLDFPLTF"
     J_segment       403..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>443
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtta tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcctg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cacctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acacagattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcagtc tctagatttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaatc gag
//
LOCUS       KCVT01000719             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24424:14754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000719
VERSION     KCVT01000719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24424:14754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78244.1"
                     /translation="CQQHDNSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc aaggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctctct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtgt
      181 tagcgactgg ttggcctggt atcaacagag accagggaaa gcccctaaac tcctgatcta
      241 tagggcgtcc aatttggata caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgctacat attactgtca
      361 acagcatgat aattcccctc cgacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000720             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:23160:21750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000720
VERSION     KCVT01000720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23160:21750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78245.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggagcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01000721             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17848:13461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000721
VERSION     KCVT01000721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17848:13461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78246.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000722             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:29395:15527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000722
VERSION     KCVT01000722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:29395:15527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78247.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggaggc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000723             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:26870:9271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000723
VERSION     KCVT01000723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26870:9271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78248.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccagc agaaacctgg gcaggctccc aggctcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtggc agtgagtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca gtttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000724             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11828:18670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000724
VERSION     KCVT01000724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11828:18670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78249.1"
                     /translation="CGQGTHIPWTF"
     J_segment       394..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          102 a          120 c          115 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 ctacacacca atggaaacat attcttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttttgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcggacaagg aacacacatt ccttggacgt tcggccaagg gaccaacgtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000725             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24558:21221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000725
VERSION     KCVT01000725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24558:21221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78250.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01000726             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10049:17211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000726
VERSION     KCVT01000726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10049:17211"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78251.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          115 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgctga cccagactcc
      121 actctccctg cccgtcactc ttggagaccc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000727             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14213:6596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000727
VERSION     KCVT01000727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14213:6596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..428
                     /note="immunoglobulin light chain variable region"
     V_region        92..428
     V_segment       92..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78252.1"
                     /translation="CGQGTQLPPTF"
     J_segment       395..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           97 a          122 c          117 g           95 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg ggatgttgtg atgactcagt ctccactctc
      121 cctgcccatc acccctggac agccggcctc catctcctgc aggtctagtc aaagccttgt
      181 acacatcaat ggaaacacat acttgagttg gtatcaccag aagccaggcc aacctccaag
      241 gcgcctaatt tatgaggttt cttaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt
      361 ttattactgc gggcaaggta cacagcttcc tcccacgttc ggccaaggga ccaaggtgga
      421 catcaaacga g
//
LOCUS       KCVT01000728             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14965:9805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000728
VERSION     KCVT01000728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14965:9805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78253.1"
                     /translation="CQQDFGWPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          118 c          118 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac tctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcgtttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttact
      361 gtcagcagga ttttggctgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000729             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17974:11409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000729
VERSION     KCVT01000729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17974:11409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..276
                     /note="immunoglobulin light chain variable region"
     V_region        8..276
     V_segment       8..239
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78254.1"
                     /translation="CQQYNNDPPTF"
     J_segment       242..276
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           76 a           74 c           67 g           62 t
ORIGIN      
        1 acatgggagt caccatcact tgtcgggcga gtcagggcat tagcagtcat ttagcgtggt
       61 atcagcagaa accagggaaa gccccgaagc ccttgatcta ttacgcatcc aatttggaaa
      121 gtggggtccc atcaaggttc agcggcagtg gatctgggac agacttcact ctcaccatca
      181 gtagcctgca gcctgaagat tttgcaactt attactgtca acagtataac aatgaccctc
      241 ccactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000730             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10857:10592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000730
VERSION     KCVT01000730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10857:10592"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78255.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca acagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01000731             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:28628:11656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000731
VERSION     KCVT01000731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:28628:11656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78256.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          109 c          109 g           98 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agatatttaa attggtatca gcagaaaccg gggaaagccc ctaagttcct
      241 gatctattat gtaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ttgtcaacag tataatagtt taccgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000732             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15325:18579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000732
VERSION     KCVT01000732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15325:18579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78257.1"
                     /translation="CIQSLEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          111 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc ttctcctgta ggtctagtca
      181 cagcctcttg gatagtgagg atggatatat ccatttggat tggtatctgc agaagccagg
      241 ccagtctcca cacctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gtttagtggc agtgggtcag acactgattt cacactgaaa atcagcaggg tggaggctga
      361 ggatgttggg gtttactact gcatacaatc tctagagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000733             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:28297:11408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000733
VERSION     KCVT01000733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:28297:11408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78258.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtta catccagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01000734             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14693:8354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000734
VERSION     KCVT01000734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14693:8354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78259.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          123 c          115 g           85 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000735             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9995:14803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000735
VERSION     KCVT01000735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9995:14803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78260.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          102 a          121 c          115 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcactactgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gaacacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaccctcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttgga
      361 atttattact gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000736             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18325:22755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000736
VERSION     KCVT01000736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18325:22755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78261.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcgaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000737             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20755:20869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000737
VERSION     KCVT01000737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20755:20869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78262.1"
                     /translation="CMQPLDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcag ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaacct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000738             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18634:9326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000738
VERSION     KCVT01000738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18634:9326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78263.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          125 c          119 g           89 t
ORIGIN      
        1 acatggggag agctctgggg aggaattgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac caacaaaaac ctgggcaggc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000739             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26317:5036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000739
VERSION     KCVT01000739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26317:5036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78264.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcttagcctg gtaccagcag aaacctgggc aggctcccag gctcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcagt ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01000740             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22164:5127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000740
VERSION     KCVT01000740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22164:5127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78265.1"
                     /translation="CMQTLEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccggtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaaa ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000741             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23904:11916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000741
VERSION     KCVT01000741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23904:11916"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78266.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          117 g          111 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct cttgagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000742             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13682:8106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000742
VERSION     KCVT01000742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13682:8106"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78267.1"
                     /translation="CLHYNSDPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          108 c          106 g          103 t
ORIGIN      
        1 acatggggaa gttagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc tgtaagagac agagtcacct tcacttgcag ggcaagtcag
      181 ggcattacaa ctttttttaa ttggtgtcag cagaaatcag gaaaaactcc taagcgcctg
      241 atctgtgttg aatacagttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacaggtt tcactctcac catcagcagc ctgcagcctg aagattttac aacttattcc
      361 tgtcttcatt ataacagtga cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000743             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14465:7622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000743
VERSION     KCVT01000743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14465:7622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78268.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000744             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10636:15453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000744
VERSION     KCVT01000744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10636:15453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78269.1"
                     /translation="CMQTLDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agcctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000745             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19774:14877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000745
VERSION     KCVT01000745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19774:14877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78270.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          120 c          110 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01000746             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20354:5663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000746
VERSION     KCVT01000746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20354:5663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78271.1"
                     /translation="CMQSLELPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          124 c          114 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcgtccatc tcctgcaggt ctagtcagag
      181 cctcgtggat agtgaggatg gaaacaccta tttggaatgg ttcctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgacgtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagcttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01000747             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5088:8329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000747
VERSION     KCVT01000747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5088:8329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78272.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaatacc tatttggaat ggcaccggca gatgccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000748             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20338:13957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000748
VERSION     KCVT01000748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20338:13957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78273.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000749             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:11670:3795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000749
VERSION     KCVT01000749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11670:3795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78274.1"
                     /translation="CQQGYGFPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           98 a          119 c          103 g          102 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcgcgatc acttgcctgg cgagtcaagg
      181 cattggcaat aatttaaatt ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 ctatacggca tccaatttac atggtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcaacagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatggttttc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01000750             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9758:4564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000750
VERSION     KCVT01000750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9758:4564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78275.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggctc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000751             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12541:14731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000751
VERSION     KCVT01000751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12541:14731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78276.1"
                     /translation="CQQYSGLPPTF"
     J_segment       383..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>420
                     /gene="IGKC"
BASE COUNT          103 a          111 c          110 g           96 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcag ttgccgggca agtcaagaca
      181 ttagcaggtt tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 attatacaga ccgtttagaa actggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcag tttcaccatc agcagcctac aacctgacga ttttgcaact tattactgtc
      361 aacagtatag tggtttacct cccactttcg gcggggggac caaggtggag atcagacgag
//
LOCUS       KCVT01000752             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12391:14573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000752
VERSION     KCVT01000752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12391:14573"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78277.1"
                     /translation="CGQGTHLPWTF"
     J_segment       269..306
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           82 a           78 c           87 g           62 t
ORIGIN      
        1 acatgggcac ccctggacag ccggcctcca tctcctgtag gtctagtcaa agccttgtac
       61 acatcaatgg aaacacatac ttgagttggt atcagcagaa cccaggccaa cctccaaggc
      121 gcctaattta tgaggtttct aaccgggact ctggggtccc agacagattc agcggcagtg
      181 gggcagggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttgggcttt
      241 attactgcgg gcaaggtaca caccttccgt ggacgttcgg ccaagggacc aaggtggaaa
      301 tcaaacgag
//
LOCUS       KCVT01000753             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13863:8740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000753
VERSION     KCVT01000753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13863:8740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78278.1"
                     /translation="CLQFKSYPNSF"
     J_segment       387..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          101 a          116 c          109 g           99 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc ctaagctcct
      241 catctatgct gcatccactt tggccggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tttaaaagtt acccgaacag ttttggccag gggaccaaag tggagatcaa
      421 gcgag
//
LOCUS       KCVT01000754             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20643:5189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000754
VERSION     KCVT01000754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20643:5189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78279.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtggg gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000755             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17389:16511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000755
VERSION     KCVT01000755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17389:16511"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78280.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          128 c          115 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg ctgacgcagt
      121 ctccagccac cctgtccttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagccta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctttgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000756             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17013:16025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000756
VERSION     KCVT01000756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17013:16025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78281.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gatgctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000757             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10637:7259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000757
VERSION     KCVT01000757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10637:7259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78282.1"
                     /translation="CQQGHSYPLTF"
     J_segment       386..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          121 c          105 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccg tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca aaagtttaag ttggtatcag cagaaaccag ggaaagcccc taaactcctc
      241 atctataggg catccagttt acaaagtgga attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gtcatagtta cccactcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01000758             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14984:8621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000758
VERSION     KCVT01000758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14984:8621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78283.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttcga tagtgaggat gcaagcacct ttttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000759             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8593:9794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000759
VERSION     KCVT01000759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8593:9794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78284.1"
                     /translation="CQQYNSDPRTF"
     J_segment       392..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          118 c          114 g           90 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccgcgcac cttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000760             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8516:3785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000760
VERSION     KCVT01000760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8516:3785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    135..331
                     /note="immunoglobulin light chain variable region"
     V_region        135..331
     V_segment       135..294
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78285.1"
                     /translation="CQQYDKSPPTF"
     J_segment       297..331
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           82 a           94 c           91 g           67 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 accatcactt gcagagcccc taacctcctg atgtataggg cgtccaattt gcaaggaggg
      181 gtcccatcaa ggttcagagg aagtggatct gggacagatt tcactctcac catcagcagc
      241 ctgcagcctg aggatgtcgc tacatattac tgtcaacagt atgataagtc ccctccgacg
      301 ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000761             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23831:15015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000761
VERSION     KCVT01000761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23831:15015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78286.1"
                     /translation="CQQYDSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          115 c          107 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccgggtta gtcaggacat
      181 tagtaatttt ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatggaaac cgtttgggaa gcggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcgactt atcattgtca
      361 gcagtatgat agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000762             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17819:13576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000762
VERSION     KCVT01000762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17819:13576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78287.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccccggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000763             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9246:14854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000763
VERSION     KCVT01000763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9246:14854"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78288.1"
                     /translation="CMQALEFPYSF"
     J_segment       406..442
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          105 t
ORIGIN      
        1 acatgggtga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg agtggcacct gcagaagcca
      241 ggccagtctc cacaactctt gatttatgac gtttccagcc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccctacag ttttggccag
      421 gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01000764             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12113:12572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000764
VERSION     KCVT01000764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12113:12572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78289.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          123 c          123 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccaggctc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagg agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000765             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10190:5951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000765
VERSION     KCVT01000765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10190:5951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78290.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgtgtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000766             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8369:18686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000766
VERSION     KCVT01000766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8369:18686"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78291.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          122 c          122 g          104 t
ORIGIN      
        1 acatgggggg gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcctg gatagtgagg atggaaacac ctatttggaa tggttcctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg ctttattact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000767             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10313:7912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000767
VERSION     KCVT01000767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10313:7912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78292.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagtcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000768             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:19991:8951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000768
VERSION     KCVT01000768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19991:8951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78293.1"
                     /translation="CQQYNSLPYSF"
     J_segment       307..344
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           91 a           85 c           85 g           86 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattga gatgacccag tctccatcct ccctgtctgc
       61 ttctgtagga gacagagtca ccatcacttg ccgggcaagt cagggcgtta acgtttattt
      121 aaattggtat caacagaaac cggggaaagc ccctaagccc ctgatctttt atgcaaaccg
      181 tttggaacgt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcagc agcctgcaac ctgaagattt tgcaagttat tattgtcaac agtataatag
      301 tttaccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01000769             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14880:10867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000769
VERSION     KCVT01000769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14880:10867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78294.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          120 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagta gaggctgacg
      361 atgttggagt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000770             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19996:12327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000770
VERSION     KCVT01000770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19996:12327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78295.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          112 a          112 c          101 g           97 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000771             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17092:15453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000771
VERSION     KCVT01000771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17092:15453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78296.1"
                     /translation="CQQGYGFPFTF"
     J_segment       386..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           97 a          127 c          106 g           95 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgcaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttcac aactatttac attggtatca gcagaagcca gggaaagccc ctagcctcct
      241 gatctatgct gcatccactt tgcaaagtgg ggtcccatcc aggttcagcg gcagtggatc
      301 tggggcagat ttcactctca ccatcagcag cctgcagcct gaagatgttg ccacttatta
      361 ctgtcaacaa ggttatggct tccctttcac cttcggcccc gggaccacac tggatatcaa
      421 acgag
//
LOCUS       KCVT01000772             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13921:7528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000772
VERSION     KCVT01000772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13921:7528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78297.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgagttca cactgaaaat cagcggagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000773             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16640:13981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000773
VERSION     KCVT01000773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16640:13981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78298.1"
                     /translation="CQQNSNWPLTF"
     J_segment       379..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           99 a          123 c          111 g           85 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ccccagcaca gcttctcttc
       61 ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca gtctccagcc
      121 accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag tcagagtgtc
      181 agcagcagct tagcctggta ccaacaaaaa cctgggcagg ctcccaggct cctcatctat
      241 ggtgcatcca gcagggccac tggcatccca gacaggttca gtggcagtgg gtctgggaca
      301 gacttcactc tcaccatcac cagcctggag cctgaagatg ttgcagttta ttattgtcag
      361 cagaatagta actggcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01000774             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9499:17250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000774
VERSION     KCVT01000774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9499:17250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..417
                     /note="immunoglobulin light chain variable region"
     V_region        100..417
     V_segment       100..399
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78299.1"
                     /translation="CMQSTKDPLTF"
     J_segment       401..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           88 a          118 c          108 g          103 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctggg tccagtggcg atattttgat gacccagact
      121 ccactctcgc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agtcttctgc atagtaatgg atacacctat ttgcattggt acctgcagaa gccaggccag
      241 tctccacggc tcctgatcta taaagttacc aatcgggaat ctggggtccc agacaggttc
      301 agcggcagtg ggtcaggcat agatttcaca ctgacaatca gcagggtgga gcctgaggat
      361 gttggtgttt attactgcat gcaaagtaca aaagatcccc tcactttcgg ccccggg
//
LOCUS       KCVT01000775             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:25704:13484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000775
VERSION     KCVT01000775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25704:13484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78300.1"
                     /translation="CQHGYGIPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          117 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagtccc agtcaggaca cagcatggac atgagggccc ccactcagct
       61 cctggggttc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccaatc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc aggcgagtca
      181 ggccattagt aataatttag tctggtatca gcagcaaccg gggaaagccc ctaagctcct
      241 gatctataag gcatccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcagcat ggttatggta tcccgtggac gttcggccaa gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000776             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25533:11768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000776
VERSION     KCVT01000776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25533:11768"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78301.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctcactc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01000777             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:26369:15287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000777
VERSION     KCVT01000777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26369:15287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78302.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc caagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01000778             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16614:9448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000778
VERSION     KCVT01000778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16614:9448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78303.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000779             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6412:19415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000779
VERSION     KCVT01000779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6412:19415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78304.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          120 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gcctcttgga tagtgaggat ggaaacacct atttcgaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagta gaggctgagg
      361 atgttggagt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000780             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16633:4811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000780
VERSION     KCVT01000780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16633:4811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78305.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          119 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acgcagactc
      121 catactccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc tcagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggttga gatcaaacga g
//
LOCUS       KCVT01000781             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22151:9049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000781
VERSION     KCVT01000781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22151:9049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78306.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          122 c          115 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctttggt acatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000782             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17865:11681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000782
VERSION     KCVT01000782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17865:11681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78307.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          122 c          118 g           86 t
ORIGIN      
        1 acatggggga gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg ctcccaggct
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcagttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000783             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21706:13733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000783
VERSION     KCVT01000783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21706:13733"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78308.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacaacat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000784             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:27922:17643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000784
VERSION     KCVT01000784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:27922:17643"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78309.1"
                     /translation="CQQHDNSPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          116 c          111 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctacatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 agtattaacg actggttggc ctggtatcaa cagagaccag ggaaggcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgataattc cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000785             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8452:12897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000785
VERSION     KCVT01000785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8452:12897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78310.1"
                     /translation="CLQGYIDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          112 c          110 g           98 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtcg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000786             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4127:15399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000786
VERSION     KCVT01000786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4127:15399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78311.1"
                     /translation="CMQALEFPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc aagtcagagc
      181 ctcctggata gtgaggatgg aaacacctat ttgcactggt acttgaagaa gccaggccag
      241 tctccacagc tcttaattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttccgc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000787             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18884:2970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000787
VERSION     KCVT01000787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18884:2970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..452
                     /note="immunoglobulin light chain variable region"
     V_region        113..452
     V_segment       113..414
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <392..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78312.1"
                     /translation="CMQALEFPWTF"
     J_segment       415..452
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>455
                     /gene="IGKC"
BASE COUNT          100 a          120 c          128 g          107 t
ORIGIN      
        1 acatggggca gagtacatgg gggatcacga ctcctcaggt caccttctca caatgaggct
       61 ccctgctcag ctcctgggac tgctcatgct ctggctccct gtatccagtg gggacattgt
      121 gatgacccag actccactct ccctgcccgt cacccttgga gagccggcct ccatgtcctg
      181 caggtctagt cagagtctct tggatagtga ggatggaaac acctatttgg aatggtacct
      241 gcagaagcca ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg
      301 agtcccagac aggttcagtg gcggtgggtc agacactgat ttcacactga aaatcagcag
      361 agtggaggct gatgatgttg gggtttatta ctgcatgcaa gctctagagt ttccgtggac
      421 gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000788             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14332:17576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000788
VERSION     KCVT01000788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14332:17576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78313.1"
                     /translation="CMQALEFPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc aagtcagagc
      181 ctcctggata gtgaggatgg aaacacctat ttgcactggt acttgaagaa gccaggccag
      241 tctccacagc tcttaattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttccgc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000789             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18533:13944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000789
VERSION     KCVT01000789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18533:13944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78314.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000790             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6910:19667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000790
VERSION     KCVT01000790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6910:19667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78315.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaaaccaggc
      241 cagtctccac gactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000791             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16251:19529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000791
VERSION     KCVT01000791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16251:19529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78316.1"
                     /translation="CMQSLEFPWTF"
     J_segment       399..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           92 a          116 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctaggagcc
      181 tcttggatgt tgaggatgga aacacctatt tggactggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtctgacact gatttcacac tgaaaatcag tagagtggag gctgaggatg
      361 ttgggtttta tttctgcatg caaagtctgg agtttccttg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01000792             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13854:10472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000792
VERSION     KCVT01000792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13854:10472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-61"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78317.1"
                     /translation="CQQGYSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          118 c          106 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tgacaataac ttgaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tggggcattc tattcccaaa gtgggattcc ctctcggttc agcggcagtg aatctgggac
      301 gggtttctct ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttaccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000793             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13598:5607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000793
VERSION     KCVT01000793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13598:5607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78318.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          107 g           90 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 gtattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctta
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatatttct
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000794             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16558:10613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000794
VERSION     KCVT01000794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16558:10613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..350
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78319.1"
                     /translation="SMHDYGWPTTF"
     J_segment       376..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT           97 a          113 c          113 g           90 t
ORIGIN      
        1 acatggggga gcaccgcctg ccagcatgtt cttgggagtt caggtgcagc tcctctggag
       61 cctggctttc tggagggcag tgagtggaga catcatcctg aaccagacgc cagcatccct
      121 gactgcacct ccaggagaga cagtgtccat ctcctgccaa gccagaccag atgtacatgg
      181 tgaaatacct tggatccgga taaaccttga acaaagactt gaaccccttt tatctcatgt
      241 cactaccttg gccccaggtg tcgcagcccg gttcatcacc aaggggagtg gcaccagtta
      301 tgttttcagc atcagtgacc tgcagcctgg ggactctggg gactattact ccatgcatga
      361 ctatgggtgg ccaaccactt tcggtggagg gaccaaggtg gagatcaaac gaa
//
LOCUS       KCVT01000795             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15761:21928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000795
VERSION     KCVT01000795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15761:21928"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78320.1"
                     /translation="CMQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          117 c          122 g          111 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggggag ccggcctcct tctcctgtag gtctagtcag
      181 agcctcttgg atgttgagga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttgggt tttatttctg catgcaaagt ctggagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000796             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12383:10722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000796
VERSION     KCVT01000796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12383:10722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78321.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcatc cttggagagc cggcctccat atcctgcacg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000797             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20393:11050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000797
VERSION     KCVT01000797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20393:11050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78322.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aaggcattga
      241 tctattacgc gtccactttg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cattctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcatac
      421 gag
//
LOCUS       KCVT01000798             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15466:10777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000798
VERSION     KCVT01000798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15466:10777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78323.1"
                     /translation="CQQYDSDTRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          112 g           89 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc accttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacacgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000799             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20281:7237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000799
VERSION     KCVT01000799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20281:7237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78324.1"
                     /translation="CQQDFGWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          121 c          121 g           91 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagactgttg gcagcgcctt agcctggtac caacagaaac ctgggcagac
      241 tcacaaactc ctcatttatg gtgcatccag cagggccacc ggcatcccag acaggttcag
      301 tggcagtggg tctggaacag agttcactct caccatcagt agtccggagc ctgaggatgt
      361 tggagtttat tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01000800             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:27764:11412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000800
VERSION     KCVT01000800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27764:11412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78325.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          105 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtgga gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaatac ctatttggaa tggcaccggc agatgccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctgacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01000801             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14825:8772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000801
VERSION     KCVT01000801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14825:8772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78326.1"
                     /translation="CQQGYGFPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          119 c          104 g          102 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcgcga tcacttgcct ggcgagtcaa
      181 ggcattggca ataatttaaa ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atctatacgg catccaattt acatggtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcaacagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatggttt tccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01000802             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20691:16751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000802
VERSION     KCVT01000802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20691:16751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78327.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt cgaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000803             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10286:10252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000803
VERSION     KCVT01000803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10286:10252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78328.1"
                     /translation="CMQALQFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          121 c          116 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacac ctcttgattt atgagttttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac tctgaatatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct acaatttccg tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000804             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14332:5315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000804
VERSION     KCVT01000804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14332:5315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78329.1"
                     /translation="CQQYYSTPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          105 a          112 c          123 g          101 t
ORIGIN      
        1 acatggggga gctacaacag gcaggcaggg gcagcaagat ggtgtcacag acccaagtct
       61 tcatttccct gttgctctgg atctctggtg cctgtgggga cattgtgatg acccagtcgc
      121 cagactccct ggctgtgtct ctgggagaga gggtcaccat caactgcaag tccagccaga
      181 gtcttttacg cgtctccaac aataggaact acttagcctg gtatcagcag aaaccagggc
      241 aggctcctaa attgctcatt tactgggcat ctacccggga attcgggatc cctaaccgat
      301 tcagtggcag tggatctggg tcagatttca ctctcaccat cagtggcctg caggctgaag
      361 atgtggcagt gtattactgt cagcagtatt atagcactcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000805             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14172:4917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000805
VERSION     KCVT01000805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14172:4917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78330.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          117 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000806             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:4389:12712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000806
VERSION     KCVT01000806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4389:12712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78331.1"
                     /translation="CMQTLEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           94 a          121 c          124 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccggtg gggacattgt gatgacccag
      121 gctccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatggtga ggatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa actctagagt ttcctctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000807             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12845:2246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000807
VERSION     KCVT01000807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12845:2246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78332.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagtctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcccgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000808             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8912:3265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000808
VERSION     KCVT01000808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8912:3265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78333.1"
                     /translation="CLQYKGYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          107 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagcagttct ttacattggt ttcaacacaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa ggttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000809             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19062:13287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000809
VERSION     KCVT01000809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19062:13287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78334.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacaaca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000810             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:4015:12036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000810
VERSION     KCVT01000810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4015:12036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78335.1"
                     /translation="CQQYNNDPPTF"
     J_segment       388..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          122 c          104 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattagc agtcatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagac ttcactctca ccatcagtag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacaatg accctcccac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01000811             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9697:14267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000811
VERSION     KCVT01000811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9697:14267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78336.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          124 c          114 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01000812             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21980:9368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000812
VERSION     KCVT01000812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21980:9368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78337.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtagcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000813             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18756:15289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000813
VERSION     KCVT01000813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18756:15289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78338.1"
                     /translation="CQQHNGYPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          120 c          111 g           90 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag
      181 tcagggcatt accaatgatt tagcctggta tcagcagaga ccagggaaag ccccgaagcc
      241 cctgatctat tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttattgtcaa cagcataatg gataccctcc gacgttcggc caagggacca gggtggaaat
      421 caaacgag
//
LOCUS       KCVT01000814             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:3337:8857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000814
VERSION     KCVT01000814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3337:8857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78339.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcaccttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01000815             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15987:11264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000815
VERSION     KCVT01000815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15987:11264"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78340.1"
                     /translation="CMQALEFPYSF"
     J_segment       400..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta ttgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc ttctgcaggt ctagtcagag
      181 cctcatggat agtggggatg taaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacat ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cggatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tacagttttg gccaggggac
      421 cagagtggag atcaaacgag
//
LOCUS       KCVT01000816             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21814:9937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000816
VERSION     KCVT01000816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21814:9937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..371
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78341.1"
                     /translation="CQQYYSFPITF"
     J_segment       385..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          100 a          113 c          112 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg atcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca aagtcaccat cacttgccga gccagtcagg
      181 gtattaacac ctggttaatt tggtatcagc agaaaccagg gaaagcccct aaggccctga
      241 tctataaggc atccagtttg caaggtgggg tcccttccag gttcagcggc agtggatctg
      301 gggcagactt cactctcacc atcaccaacc tgcagcctga agattttgga atttattact
      361 gtcaacaata ttatagtttt ccgatcactt tcggtggggg gaccaaggtg gagatcaggc
      421 gag
//
LOCUS       KCVT01000817             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:25684:20604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000817
VERSION     KCVT01000817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25684:20604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78342.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          118 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttgtt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000818             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12379:6290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000818
VERSION     KCVT01000818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12379:6290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78343.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc agaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cattctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000819             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10031:16309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000819
VERSION     KCVT01000819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10031:16309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..368
                     /note="immunoglobulin light chain variable region"
     V_region        88..368
     V_segment       88..328
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78344.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       336..368
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           99 a           90 c           93 g           89 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca caggatggac atgacggtcc ccgcttatct
       61 cctggggctc cttctgctct ggctcccagg agacaaagtc accatcactt gcagggcaag
      121 tcaggacatt ggtaattatt taaattggta tcagcagaaa ccaggaaaag ctcctaaggt
      181 cctgatctat ggtgtatcca atttacaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gatcttactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttattgtcaa ccgtttaaaa gttacctttc ggtccctttc ggcggaggga ccaaggtgga
      361 gatcaaacga g
//
LOCUS       KCVT01000820             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11340:13918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000820
VERSION     KCVT01000820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11340:13918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78345.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaaca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000821             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21045:6807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000821
VERSION     KCVT01000821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21045:6807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78346.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          102 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccttaaag tcctgatctt
      241 tagggcatcc agtttacaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca ccagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000822             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15311:20542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000822
VERSION     KCVT01000822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15311:20542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78347.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          118 c          107 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tctccatcac ttgtcgggca agtcagggca
      181 ttacgaatga tttagcctgg tatcagcaga aaccaggtaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01000823             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9740:19452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000823
VERSION     KCVT01000823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9740:19452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78348.1"
                     /translation="CQQYNSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          113 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000824             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9207:5437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000824
VERSION     KCVT01000824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9207:5437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78349.1"
                     /translation="CMQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           85 a          124 c          124 g          105 t
ORIGIN      
        1 acagggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgctg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagagg ccaggccagt
      241 ctccacaact tctggtctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caagatatac agcttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01000825             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17980:6725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000825
VERSION     KCVT01000825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17980:6725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..383
                     /note="immunoglobulin light chain variable region"
     V_region        110..383
     V_segment       110..341
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78350.1"
                     /translation="CQQYNSEPRTF"
     J_segment       349..383
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           96 a          104 c          103 g           83 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcacttgt cgggcgagtc agggcattcg cagttattta gcgtggtatc agcagaaact
      181 agggaaaccc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      241 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      301 tgaagatttt gcaacttatt actgtcaaca gtataacagt gagccgcgca ctttcggtgg
      361 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01000826             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10997:13347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000826
VERSION     KCVT01000826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10997:13347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..348
                     /note="immunoglobulin light chain variable region"
     V_region        27..348
     V_segment       27..299
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78351.1"
                     /translation="CQQHESYPLTF"
     J_segment       311..348
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           93 a          100 c           82 g           76 t
ORIGIN      
        1 acatggggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca tcctccctgt
       61 ctgcatctgt aggagacaca gtcaccatca cttgtcgggc aagtcacgac attagcgatt
      121 ctttagcctg gtatcagcac aaaccaggaa aagccccgaa gcccctgatc tattacgcat
      181 ccaatttgaa aagtggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca
      241 ctctcaccat cagcagcctg cagcctgaag attttgcaac ctattactgt caacagcatg
      301 aatcttaccc gctcactttc ggcggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000827             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12286:8027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000827
VERSION     KCVT01000827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12286:8027"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78352.1"
                     /translation="CMQTLEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          121 c          123 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccggtgg ggacattgtg atgacccagg
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaaa ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000828             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15233:19813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000828
VERSION     KCVT01000828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15233:19813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78353.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaacccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttta ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01000829             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:5556:12221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000829
VERSION     KCVT01000829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:5556:12221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78354.1"
                     /translation="CQQGYNTPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          113 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgttctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattagca gctggttagc ctggtatcag cagaaaccag ggaaagcccc tagactccta
      241 atctataagg cgtccacttt ggcaagtggg gtcccatcaa ccttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagg ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagg gttacaatac cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000830             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12709:19352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000830
VERSION     KCVT01000830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12709:19352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78355.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg acatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000831             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10694:6651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000831
VERSION     KCVT01000831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10694:6651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78356.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          121 g          109 t
ORIGIN      
        1 acatgggggt tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000832             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8378:5593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000832
VERSION     KCVT01000832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8378:5593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78357.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000833             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20142:9664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000833
VERSION     KCVT01000833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20142:9664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78358.1"
                     /translation="CQKYISSPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          132 c          109 g           93 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaacttat
      121 attgactcag tctccagcca ccctgtctct gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcctctatg gtacatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcagtatat tactgtcaga aatatattag ctccccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01000834             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24316:18815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000834
VERSION     KCVT01000834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24316:18815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78359.1"
                     /translation="CQQGYSYPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          122 c          105 g           94 t
ORIGIN      
        1 acatgggagt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg caggagacac agtcaccatc acttgccagg cgagtcaagc
      181 cattggcaat actttaaatt ggtatcaaca gaaaccaggg aaagccccta cacccctgat
      241 ctatagggca tccggtttgc aaagtgggac tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gactttgcca cttattactg
      361 tcaacagggt tatagttatc cgtacagttt tggccagggg accaaactgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000835             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21962:9233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000835
VERSION     KCVT01000835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21962:9233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78360.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aaggccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01000836             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14570:10861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000836
VERSION     KCVT01000836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14570:10861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78361.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaccc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000837             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10716:5145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000837
VERSION     KCVT01000837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10716:5145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78362.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgtgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000838             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19642:2639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000838
VERSION     KCVT01000838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19642:2639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78363.1"
                     /translation="CQQHDDSPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          117 c          108 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tggcaactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctcca gcctgaagat atcgcaacat attactgtca
      361 acaacatgat gattccccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000839             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12856:14852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000839
VERSION     KCVT01000839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12856:14852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78364.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcaccagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01000840             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8897:2983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000840
VERSION     KCVT01000840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8897:2983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78365.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 ggtactgcta atgctctggc tccctggatc cagcggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat gctgaggatg gaaacaccta cttggaatgg tatttacaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aagctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000841             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14872:19929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000841
VERSION     KCVT01000841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14872:19929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78366.1"
                     /translation="CMQAREFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          126 c          116 g          103 t
ORIGIN      
        1 acatggggat tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ttccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt cgatagtgag gaggggaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tctccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgctgg ggtttattac tgcatgcaag ctcgagagtt tccattcact ttcggccccg
      421 ggaccaaact ggacatcaaa cgag
//
LOCUS       KCVT01000842             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19688:17170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000842
VERSION     KCVT01000842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19688:17170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78367.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01000843             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18078:5923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000843
VERSION     KCVT01000843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18078:5923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78368.1"
                     /translation="CQQYHSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagca gttatttagc gtggtatcgg cagaagccag ggaaagcccc ggagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctacagcctg aagattttgc aacttattac
      361 tgtcaacagt atcacagtga ctcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000844             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22101:8073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000844
VERSION     KCVT01000844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22101:8073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78369.1"
                     /translation="CMQSLEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtcg
      181 gagcctcttg gatagtgacg atggaaacac ctatttggac tggtacctgc agaagccagg
      241 ccggtctcca caggtcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gatcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggc atttattact gcatgcaaag tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000845             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17767:11134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000845
VERSION     KCVT01000845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17767:11134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78370.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagggggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000846             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21781:20701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000846
VERSION     KCVT01000846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21781:20701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78371.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000847             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15619:14505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000847
VERSION     KCVT01000847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15619:14505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..355
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78372.1"
                     /translation="SMHDYGWPTTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           97 a          114 c          115 g           92 t
ORIGIN      
        1 atggggaggc tctgagcacc gcctgccagc atgttcttgg gagttcaggt gcagctcctc
       61 tggagcctgg ctttctggag ggcagtgagt ggagacatca tcctgaacca gacgccagca
      121 tccctgactg cacctccagg agagacagtg tccatctcct gccaagccag accagatgta
      181 catggtgaaa taccttggat ccggataaac cttgaacaaa gacttgaacc ccttttatct
      241 catgtcacta ccttggcccc aggtgtcgca gcccggttca tcaccaaggg gagtggcacc
      301 agttatgttt tcagcatcag tgacctgcag cctggggact ctggggacta ttactccatg
      361 catgactatg ggtggccaac cactttcggt ggagggacca aggtggagat caaacgaa
//
LOCUS       KCVT01000848             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15109:11260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000848
VERSION     KCVT01000848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15109:11260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78373.1"
                     /translation="CMQALEFPYSF"
     J_segment       406..442
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           99 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg agtggcacct gcagaagcca
      241 ggccagtctc cacaactctt gatttatgac gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccctacag ttttggccag
      421 gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01000849             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25345:20369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000849
VERSION     KCVT01000849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25345:20369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78374.1"
                     /translation="CQQGYSYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgccc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccctc
      121 ctccctgtcc gcatctgtgg gagacgcagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataac ttaaattggt ttcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttacccgt ggacgttcgg ccaaggggcc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000850             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:26265:16055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000850
VERSION     KCVT01000850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:26265:16055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78375.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt gggatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000851             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9238:19604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000851
VERSION     KCVT01000851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9238:19604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78376.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctccagcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000852             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12018:20843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000852
VERSION     KCVT01000852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12018:20843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78377.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca ctcttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaaaccagg
      241 ccagtctcca cgactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000853             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:25200:6717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000853
VERSION     KCVT01000853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25200:6717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    60..381
                     /note="immunoglobulin light chain variable region"
     V_region        60..381
     V_segment       60..343
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <321..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78378.1"
                     /translation="CQQYNSLPYIF"
     J_segment       344..381
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>384
                     /gene="IGKC"
BASE COUNT          105 a           98 c           93 g           88 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgccc gccagatgtg
       61 acattcagat gacccagtct ccatcctccc tgtctgcttc tgtaggagac agagtcacca
      121 tcacttgccg ggcaagtcag gacattagcg tttttttaaa ttggtatcag cagaaaccgg
      181 ggaaagcccc taaacccctg atctattatg caaaccgttt ggaaagtggg gtcccatcaa
      241 ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc ctgcaacctg
      301 aagattttgc aacttattac tgtcaacagt ataatagttt accgtacatt tttggccagg
      361 ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01000854             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8589:17235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000854
VERSION     KCVT01000854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8589:17235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78379.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          120 c          107 g           89 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000855             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:23041:18512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000855
VERSION     KCVT01000855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23041:18512"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78380.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          120 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagaa actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000856             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17215:18381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000856
VERSION     KCVT01000856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17215:18381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..357
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78381.1"
                     /translation="SMHDSGGPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           95 a          114 c          119 g           92 t
ORIGIN      
        1 acatgggggg gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tctccatctc ctgccaagcc agagcagatg
      181 tacatggtga aatgtcttgg atccggataa accttgaaca aagacttgaa ccccttttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagcccggtt catcagcaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgactc tggggggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01000857             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17620:3398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000857
VERSION     KCVT01000857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17620:3398"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..275
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78382.1"
                     /translation="CQQYNTLPLTF"
     J_segment       276..306
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>316
                     /gene="IGKC"
BASE COUNT           82 a           79 c           79 g           76 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc
       61 cgggcaagtc aggacattaa catttattta aattggtatc agcagaaacc ggggaaagcc
      121 cctgagctcc tgatctatta tgcaaaccgt ttggaaactg gggtcccatc aaggttcagc
      181 ggcggtggat ctgggacaga attcagtctc accatcagca gcctgcaacc tgaggacttt
      241 gcaacttatt actgtcaaca gtataatact ttaccgctca ctttcggcgg agggaccaag
      301 gtggaggtca gacgag
//
LOCUS       KCVT01000858             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22454:2996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000858
VERSION     KCVT01000858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22454:2996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78383.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcttccct gtctgcttct gtaggagacg gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaggccctga
      241 tctattatgc aaaccggttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaatctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagta gagatcaaac
      421 gag
//
LOCUS       KCVT01000859             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16384:7232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000859
VERSION     KCVT01000859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16384:7232"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..401
                     /note="immunoglobulin light chain variable region"
     V_region        62..401
     V_segment       62..364
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78384.1"
                     /translation="CMQALEFPLTF"
     J_segment       367..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           88 a          107 c          112 g           97 t
ORIGIN      
        1 acatgggctc cctgctcagc tcctgggact gctaatgctc tggctccctg gatccagtgg
       61 ggacattgtg atgacccaga ctccactctc cctgcccgtc acccttggag agccggcctc
      121 catctcctgt aggtctagtc agagcctctt ggatagtgaa gatggaaata cctatttgga
      181 atggcaccgg cagatgccag gccagtctcc acagctcttg atttatgagg tttccaaccg
      241 ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcactctgaa
      301 aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaag ctctagagtt
      361 tcctctgacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000860             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13539:5370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000860
VERSION     KCVT01000860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13539:5370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78385.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          117 c          122 g          107 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcactct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaagatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01000861             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18230:14859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000861
VERSION     KCVT01000861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18230:14859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78386.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          121 c          108 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataataat tactctccca ctttcggcgg agggaccacg gtggagatca
      421 aacgag
//
LOCUS       KCVT01000862             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16957:5129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000862
VERSION     KCVT01000862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16957:5129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78387.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          110 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgt aaaccatttg gaaagtgggg tcccatcaac gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tccaacctga agattttgca acttattact
      361 gtcaacaata taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000863             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20706:9489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000863
VERSION     KCVT01000863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20706:9489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..409
                     /note="immunoglobulin light chain variable region"
     V_region        126..409
     V_segment       126..372
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78388.1"
                     /translation="CIQSLEFPWTF"
     J_segment       373..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           92 a          106 c          111 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaccgggg acattgtgat gacccagact
      121 ccactctcct tctcctgtag gtctagtcac agcctcttgg atagtgagga tggaaatatc
      181 catttggatt ggtatctgca gaagccaggc cagtctccac acctcttgat ttatgaggtt
      241 tccaaccggg cctctggagt cccagacagg tttagtggca gtgggtcaga cactgatttc
      301 acactgaaaa tcagcagggt ggaggctgag gatgttgggg tttactactg catacaatct
      361 ctagagtttc cttggacgtt cggccagggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000864             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11435:12991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000864
VERSION     KCVT01000864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11435:12991"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78389.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg ccagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000865             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17045:13175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000865
VERSION     KCVT01000865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17045:13175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78390.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          116 c          105 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcatcatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000866             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:27525:9206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000866
VERSION     KCVT01000866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:27525:9206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78391.1"
                     /translation="CLQESNWSYSF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          120 c          121 g           86 t
ORIGIN      
        1 acatggggga aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gatagtaccg gagaaatagt ggtgacacag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca aaagcaggtt agcctggtac cagcagaaac ctgggcaagc tcccaggctc
      241 ctcatgtatg atgcgtccag cagggccact ggcatcccag acaggttcac tggcagcggg
      301 tctgggccag agttcactct caccatcagc agcctggagc ctgaagatgt tgcggtttat
      361 ttctgtcttc aggagagtaa ctggtcgtac agctttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01000867             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9007:18495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000867
VERSION     KCVT01000867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9007:18495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..452
                     /note="immunoglobulin light chain variable region"
     V_region        113..452
     V_segment       113..415
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <392..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78392.1"
                     /translation="CMQALEFPLTF"
     J_segment       416..452
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>455
                     /gene="IGKC"
BASE COUNT           97 a          123 c          129 g          106 t
ORIGIN      
        1 acatggggca gagtacatgg gggatcacga ctcctcaggt caccttctca caatgaggct
       61 ccctgctcag ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt
      121 gatgacccag actccactct ccctgtccgt cacccttgga gagccggcct ccatctcctg
      181 caggtctagt cagagcctct tggatggtga ggatggaaac acctacttgg aatggtattt
      241 ccagaagcca ggccagtctc cacagctctt gatttatgag gtctccaagc gggcctctgg
      301 agtcccagac aggttcagtg gcagtgggtc aggcactgat ttcacactga aaatcagcag
      361 cgtggaggct gaggatgttg gggtttatca ctgcatgcaa gctctagagt ttcctctcac
      421 tttcggcgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000868             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9538:2320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000868
VERSION     KCVT01000868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9538:2320"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78393.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtggtg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01000869             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15085:15031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000869
VERSION     KCVT01000869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15085:15031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..341
                     /note="immunoglobulin light chain variable region"
     V_region        20..341
     V_segment       20..304
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78394.1"
                     /translation="CQQHDDSPRTF"
     J_segment       306..341
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           95 a           90 c           84 g           75 t
ORIGIN      
        1 acatgggggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
       61 tgtaggagac agagtcacca tcacttgcac agccagtcag ggtattaata actggttggc
      121 ctggtatcaa cagaaaccag gaaaagcccc taaactcctt atctataggg catccaattt
      181 ggaaacaggg gtcccatcga ggttcggtgg aagtggatct gggacagatt tcactctcac
      241 catcagcagc ctgcagcctg aagatatcgc aacatatttc tgtcaacagc atgatgattc
      301 ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000870             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15863:8028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000870
VERSION     KCVT01000870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15863:8028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78395.1"
                     /translation="CQQHDNSPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          120 c          114 g           89 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctctctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcagggtgtt agcgactggt tggcctggta tcaacagaga ccagggaaag cccctaaact
      241 cctgatctat agggcgtcca atttggatac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgctacata
      361 ttactgtcaa cagcatgata attcccctcc gacgttcggc caagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000871             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11217:7973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000871
VERSION     KCVT01000871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11217:7973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78396.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggt ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000872             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17495:11528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000872
VERSION     KCVT01000872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17495:11528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78397.1"
                     /translation="CMQPLDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcagcc ttggagagcc ggcctccatt ttctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaacctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000873             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16667:12391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000873
VERSION     KCVT01000873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16667:12391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78398.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          119 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000874             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17076:13988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000874
VERSION     KCVT01000874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17076:13988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..446
                     /note="immunoglobulin light chain variable region"
     V_region        125..446
     V_segment       125..408
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78399.1"
                     /translation="CHQGNSFPWTF"
     J_segment       409..446
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>449
                     /gene="IGKC"
BASE COUNT          115 a          112 c          115 g          107 t
ORIGIN      
        1 acatggggag aggctctttc tctgggatgt ggcatgagca aaactgacaa gtcaaggcag
       61 gaagatgttg tctccatcac aactcattgg gtttctgctg ctctgggttc cagcctccaa
      121 gggtgaaatt gtgctgactc agtctccagt ctttcggtct gtgactctaa aggagaaagt
      181 caccatcacc tgccaggcca gtcagaacat tggtaataag ctacactggt accagcagaa
      241 accggatcag tctccaaagc tcctcatcaa gtatgcttcc cagtccatct caggggtccc
      301 ctcaaggttc agtggcagtg gatctgggac agatttcacc cttaccatca atagcctgga
      361 agctgaagat gctgcgacgt attactgtca ccagggtaat agttttccgt ggacgttcgg
      421 ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01000875             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16986:13153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000875
VERSION     KCVT01000875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16986:13153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78400.1"
                     /translation="CQQGYTTPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          117 c          112 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagttcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 attgtccctg tctgcatctg taggagacaa agtcaccatc acttgccgag ccagtcaggg
      181 tattagcagc tggttagcct ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 ctataaggcg tccagtttgg caagtggggt cccatcaagg ttcagcggca gtgggtctgg
      301 gacggattac actctcacca tcaacagcct gcagcctgaa gattttacaa cttattattg
      361 tcaacagggt tacactaccc ctctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000876             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15034:16744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000876
VERSION     KCVT01000876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15034:16744"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78401.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          108 c          109 g          100 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attgagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cgttaacgtt tatttaaatt ggtatcaaca gaaaccgggg aaagccccta agcccctgat
      241 tttttatgca aaccgtttgg aacgtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa gttattattg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000877             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:9984:12668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000877
VERSION     KCVT01000877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9984:12668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..390
                     /note="immunoglobulin light chain variable region"
     V_region        69..390
     V_segment       69..348
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <330..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78402.1"
                     /translation="CQQYDSDSLTF"
     J_segment       353..390
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>393
                     /gene="IGKC"
BASE COUNT           94 a          109 c           99 g           91 t
ORIGIN      
        1 acatgggcat gagggtcccc gctcagctcc taggactcct gctgctctgt ctcccaggtg
       61 ccaaatgtga catccagatg acccagtctc catcctccct gtctgcatct gtaggagaca
      121 gagtcaccat cacttgtcgg gcgactcagg acattcgcag ttatttagcg tggtatcagc
      181 agaaaccagg gaaagccccg aagcccttga tctattacgc gtccactttg gaaagtgggg
      241 tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc atcagcagcc
      301 tgcagcctga agattttgca acttattact gtcaacagta tgacagtgat tcgctcactt
      361 tcggtggagg gaccaacgtg gagatcaaac gag
//
LOCUS       KCVT01000878             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14028:16088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000878
VERSION     KCVT01000878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14028:16088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78403.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggga ttacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000879             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10492:20112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000879
VERSION     KCVT01000879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10492:20112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78404.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          115 c          126 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ctagtgggga tgttgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01000880             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20740:12615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000880
VERSION     KCVT01000880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20740:12615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78405.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          119 c          106 g           87 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagccacga
      181 tataaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatttcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01000881             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17203:14545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000881
VERSION     KCVT01000881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17203:14545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..396
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78406.1"
                     /translation="CQQHNGYPPTF"
     J_segment       409..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          117 a          123 c          112 g           94 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggag gagtcagaac cactcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgttggag acacagtcac
      181 catcacttgt cgggcaagtc aggacattac gaatgattta gcctggtatc aacagaaacc
      241 aagtaaagcc ccgaagcccc tgatctatta cgcatccaat ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga tttcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt attgtcaaca gcataatgga taccctccga cgttcggcca
      421 agggaccagg gtggaaatca aacgag
//
LOCUS       KCVT01000882             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16231:8998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000882
VERSION     KCVT01000882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16231:8998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78407.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          123 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccacccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000883             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14189:6896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000883
VERSION     KCVT01000883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14189:6896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78408.1"
                     /translation="CQQYNSDPRTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          120 c          113 g           89 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cctgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ctactgtcaa cagtataaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000884             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13931:12872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000884
VERSION     KCVT01000884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13931:12872"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78409.1"
                     /translation="CQQGYNTPVTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          112 c          120 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcg tccctgtctg catctgttgg agacaaagtc accatcactt gccgagccag
      181 tcaggatatt agtagttggt tagtctggta tcagcagaaa ccagggaaag cccctaaggt
      241 cctgatctat aaggcgtcca gtttggcaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggacg gattacactc tcaccatcag cagcctgcag gctgaagatt ttgcaactta
      361 ttattgtcaa cagggttaca ataccccggt cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000885             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16704:9083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000885
VERSION     KCVT01000885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16704:9083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78410.1"
                     /translation="CQQYDSDLFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          114 c          112 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tttgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggtt
      301 ctgggacaga attcactctc accatcaaca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacctgttca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000886             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8644:9382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000886
VERSION     KCVT01000886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8644:9382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78411.1"
                     /translation="CQQYDSFPLTF"
     J_segment       390..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          118 c          111 g           99 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg cttctgtggg agacagagtc accatcactt gccgggctag
      181 tcaggacatt agtaattttt taaattggta tcagcagaaa ccggggaaag cccctaagct
      241 cctgatctat tatggaaacc gtttgggaag cggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaggatt ttgcgactta
      361 tcattgtcag cagtatgata gtttccccct cactttcggc cccgggacca aactggatat
      421 caaacgag
//
LOCUS       KCVT01000887             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16035:15086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000887
VERSION     KCVT01000887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16035:15086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78412.1"
                     /translation="CQQYNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          118 c          107 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataataatta ttctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000888             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15962:6307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000888
VERSION     KCVT01000888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15962:6307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..363
                     /note="immunoglobulin light chain variable region"
     V_region        66..363
     V_segment       66..325
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78413.1"
                     /translation="CQQYNSLPWTF"
     J_segment       326..363
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT          100 a           89 c           96 g           81 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      121 agggcattag ttattattta aattggtatc aacagaaacc ggggaaagcc cctaaggtcc
      181 tgatctatta cacaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      241 ctgggacaga attcactctc accatcagca gcctgcaacc tgaggatttt gcaagttatt
      301 actgtcaaca atataatagt ttaccgtgga cgttcggcca agggaccaag gtggaaatca
      361 aacgag
//
LOCUS       KCVT01000889             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15523:4989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000889
VERSION     KCVT01000889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15523:4989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78414.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcagacgag
//
LOCUS       KCVT01000890             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:3652:11532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000890
VERSION     KCVT01000890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3652:11532"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78415.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          108 c          107 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctgatcta
      241 ttatgtaaac cgtttggaaa gcggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000891             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9325:10731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000891
VERSION     KCVT01000891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9325:10731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78416.1"
                     /translation="CQQHNTYPLTF"
     J_segment       389..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          119 c          105 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 ggacattagt aatgatttag cctggtatca gcagaaacca gggacagccc cgaagcccct
      241 gatgtattac gcatccaatt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caagttatta
      361 ctgtcaacag cataatactt acccattgac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01000892             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16509:5712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000892
VERSION     KCVT01000892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16509:5712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78417.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          109 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtgggagac agagtcacca tcacttgccg ggctagtcag
      181 gacattagta attttttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattatg gaaaccgttg ggaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgcg acttatcatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000893             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16018:8034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000893
VERSION     KCVT01000893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16018:8034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78418.1"
                     /translation="CQQDFDWPPTF"
     J_segment       392..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           99 a          126 c          116 g           88 t
ORIGIN      
        1 acatgggggg ggaggaactg ctcagttagg acccagaggg aaccatggaa gctccagcac
       61 agcttctctt cctcctgcta ctctggatcc cagataccac cggagaagtt gtgatgacgc
      121 agtctccagc caccctgtct ttgtctccag gggaaagagc caccctctcc tgcagggcca
      181 gtcagagtgt tggcaacacc ttaacctggt accagcacaa acctgggcag gctcccaagc
      241 tcctcctcta tggtgcatcc accagggcct ccggcatccc aggcaggttc agtgccagtg
      301 ggtctggaac agagtttact ctcaccatca gcagcctgga gcctgaagat gttggaattt
      361 attactgtca gcaggatttt gactggcctc cgacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01000894             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20753:19552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000894
VERSION     KCVT01000894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20753:19552"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78419.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcgacagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01000895             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:7120:10794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000895
VERSION     KCVT01000895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7120:10794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78420.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000896             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11534:16587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000896
VERSION     KCVT01000896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11534:16587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78421.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          118 c          103 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 cctcctccct gtctgcgtct gtaggagtca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga tgattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01000897             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:28793:11439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000897
VERSION     KCVT01000897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28793:11439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78422.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgccggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggtatt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000898             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7371:15521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000898
VERSION     KCVT01000898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7371:15521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..311
                     /note="immunoglobulin light chain variable region"
     V_region        7..311
     V_segment       7..273
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78423.1"
                     /translation="CQQYNSLPYIF"
     J_segment       274..311
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>314
                     /gene="IGKC"
BASE COUNT           86 a           76 c           73 g           79 t
ORIGIN      
        1 acatgggtct ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg
       61 ggcaagtcag gacattagcg tttttttaaa ttggtatcag cagaaaccgg ggaaagcccc
      121 taaacccctg atctattatg caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg
      181 cagtggatct gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc
      241 aacttattac tgtcaacagt ataatagttt accgtacatt tttggccagg ggaccaaagt
      301 ggagatcaaa cgag
//
LOCUS       KCVT01000899             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18002:15801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000899
VERSION     KCVT01000899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18002:15801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78424.1"
                     /translation="CQQYNSLPYIF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          109 c          103 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacgtttat ttaaattggt atcagcagaa accggggaaa gcccctaaac ccctgatcta
      241 ttatagaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat agtttaccgt acatttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000900             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16613:7345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000900
VERSION     KCVT01000900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16613:7345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78425.1"
                     /translation="CQQYNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          118 c          104 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagata acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc ttgtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taataattat tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000901             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:16974:15483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000901
VERSION     KCVT01000901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16974:15483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..285
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78426.1"
                     /translation="CQQHDDSPRTF"
     J_segment       287..322
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           93 a           84 c           78 g           70 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc
       61 atcacttgca cagccagtca ggatattaat aactggttgg cctggtatca acagaaacca
      121 ggaaaagccc ctaaactcct gatctatagg gcatccaatt tggaaacagg ggtcccatcg
      181 aggttcggtg gaagtggatc tgggacagat ttcactctca ccattagcag cctgcagcct
      241 gaagatatcg caacatatta ctgtcaacag catgatgatt cccctcggac gttcggccaa
      301 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000902             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13454:4303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000902
VERSION     KCVT01000902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13454:4303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..347
                     /note="immunoglobulin light chain variable region"
     V_region        8..347
     V_segment       8..309
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <287..>319
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78427.1"
                     /translation="CMQALEFPWTF"
     J_segment       310..347
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>350
                     /gene="IGKC"
BASE COUNT           85 a           87 c           97 g           81 t
ORIGIN      
        1 acatggggac attgtgatga cccagactcc actctccctg cccgtcaccc ttggagagcc
       61 ggcctccatc tcctgcaggt ctagtcagag tctcttggat agtgaggatg gaaacaccta
      121 tttggaatgg tacctgcaga agccaggcca gtctccacaa ctcttgattt atgaggtttc
      181 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac
      241 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct
      301 agaatttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000903             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11677:9170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000903
VERSION     KCVT01000903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11677:9170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78428.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          116 c          108 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattaacaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaggtcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtgggtctg
      301 ggacagattt cactctcacc atcaacaacc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01000904             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14802:15976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000904
VERSION     KCVT01000904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14802:15976"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78429.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>442
                     /gene="IGKC"
BASE COUNT           91 a          120 c          126 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcagacg ag
//
LOCUS       KCVT01000905             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:6319:4377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000905
VERSION     KCVT01000905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6319:4377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78430.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          121 c          108 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacagccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctacagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccacgg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000906             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12102:9565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000906
VERSION     KCVT01000906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12102:9565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78431.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggcttc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaccctcttg gatggtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01000907             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16057:8120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000907
VERSION     KCVT01000907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16057:8120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78432.1"
                     /translation="CQQYNTLPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          112 c          104 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacgt tcagatgacc cagtctccat
      121 cctacctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaacgttta tttaaattgg tatcaccaga aaccggggaa agcccctaac ctcctgatct
      241 attatgcaaa ccgtttggaa aatggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcgact tattactgtc
      361 aacagtataa tactttaccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000908             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15095:18397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000908
VERSION     KCVT01000908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15095:18397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78433.1"
                     /translation="CLHYNSDPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          108 c          107 g          102 t
ORIGIN      
        1 acatggggga agttagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat ctgtaagaga cagagtcacc ttcacttgca gggcaagtca
      181 gggcattaca acttttttaa attggtgtca gcagaaatca ggaaaaactc ctaagcgcct
      241 gatctgtgtt gaatacagtt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacaggt ttcactctca ccatcagcag cctgcagcct gaagatttta caacttattc
      361 ctgtcttcat tataacagtg acccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01000909             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18587:4346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000909
VERSION     KCVT01000909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18587:4346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78434.1"
                     /translation="CQHHNTYPHSF"
     J_segment       385..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          121 c          105 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aggcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtcaacacca taatacttac cctcacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000910             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:23802:6865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000910
VERSION     KCVT01000910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23802:6865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78435.1"
                     /translation="CQQGHTYPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          120 c          104 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccgtgtcc gcatctgtag gagacacagt cacgatcact tgccaggcgc gtcaaggcat
      181 tggcaaaaat gtcaattggt atcagcagaa accagggaaa gcccctaaac tcgtgatcta
      241 tagggcatcc agtttgcaaa gtgagattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca acagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcat acttacccgt tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01000911             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25472:17911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000911
VERSION     KCVT01000911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25472:17911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78436.1"
                     /translation="CQQDYSWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          120 c          116 g           87 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagctcca gcacagcttg
       61 tcttcctcct gctactctgg atcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcag catcttagcc tggtaccacc agaaacctgg gcaggctccc aagtccctca
      241 tctatggtgc aaccagtagg gccaccggca tcccagacag gttcagtggc agtgggtctg
      301 gaacagagtt tactctcacc atcagcagcc tggagcctga agatgttggc gtttattact
      361 gtcagcagga ttatagctgg ccactcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000912             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:13058:20426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000912
VERSION     KCVT01000912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13058:20426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78437.1"
                     /translation="CQQDFGWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          119 c          115 g           91 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccattc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 actgttggca gcgccttagc ctggtaccag cagaaacctg ggcagactca cagactcctc
      241 atttatggtg catccttcag ggccaccggc atcccagaca ggttcagtgg cagtgggtct
      301 ggaacagagt tcactctcac catcagtagt ccggagcctg aggatgttgg agtttattac
      361 tgtcagcagg attttggctg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000913             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12165:4402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000913
VERSION     KCVT01000913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12165:4402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78438.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtatacatca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcgg ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01000914             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7130:4720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000914
VERSION     KCVT01000914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7130:4720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78439.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          122 c          113 g           93 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccat cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgcattcttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000915             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11074:22109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000915
VERSION     KCVT01000915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11074:22109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78440.1"
                     /translation="CQQHDNSPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          119 c          113 g           88 t
ORIGIN      
        1 acagggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tctctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggtgttagcg actggttggc ctggtatcaa cagagaccag ggaaagcccc taaactcctg
      241 atctataggg cgtccaattt ggatacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc tacatattac
      361 tgtcaacagc atgataattc ccctccgacg ttcggccaag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000916             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20743:13865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000916
VERSION     KCVT01000916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20743:13865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78441.1"
                     /translation="CQQYNSLPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          109 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagtt attatttaaa ttggtatcaa cagaaaccgg ggaaagcccc taaggtcctg
      241 atctattaca caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc aagttattac
      361 tgtcaacaat ataatagttt accgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000917             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6932:9245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000917
VERSION     KCVT01000917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6932:9245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78442.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          117 c          108 g           90 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagtcag
      181 ggtattaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctt
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcggtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatatttc
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000918             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13468:18141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000918
VERSION     KCVT01000918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13468:18141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78443.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           99 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt tacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatattga ggatggaaac acctatttcg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgac ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000919             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:4378:12919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000919
VERSION     KCVT01000919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:4378:12919"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..255
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78444.1"
                     /translation="CQQYDSDSLTF"
     J_segment       260..297
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           78 a           72 c           81 g           69 t
ORIGIN      
        1 acatggggtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
       61 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgagg cccttgatct
      121 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      181 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      241 aacaatatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01000920             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16819:6818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000920
VERSION     KCVT01000920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16819:6818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78445.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          123 c          118 g           92 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gactccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtacacatca atggacacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtgggacag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattcct gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01000921             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6010:11980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000921
VERSION     KCVT01000921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6010:11980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78446.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcattttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000922             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16420:17824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000922
VERSION     KCVT01000922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16420:17824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78447.1"
                     /translation="CIQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          121 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cacttttcct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacactt atttggactg gtacctacag aggccaggcc
      241 agactcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atcttgggat ttattactgc atacaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000923             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13928:15224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000923
VERSION     KCVT01000923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13928:15224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78448.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg aaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000924             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6551:2929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000924
VERSION     KCVT01000924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6551:2929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78449.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaatacc tatttggaat ggcaccggca gatgccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01000925             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17384:17787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000925
VERSION     KCVT01000925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17384:17787"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78450.1"
                     /translation="CMQGTHLPFTF"
     J_segment       390..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          119 c          110 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtctatca ctcttggaca accggcctcc atttcctgca ggtctagtca cacccttgta
      181 cacagtgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggagtt
      361 tattactgca tgcaaggtac acaccttcca ttcactttcg gccccgggac caaactggat
      421 atcaaacgag
//
LOCUS       KCVT01000926             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10667:12216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000926
VERSION     KCVT01000926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10667:12216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78451.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtcaagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgca ctggtacttg aagaagccag
      241 gccagtctcc acaggtctta atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000927             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22914:17504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000927
VERSION     KCVT01000927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22914:17504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78452.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgatggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaact atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01000928             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18650:17342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000928
VERSION     KCVT01000928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18650:17342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78453.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc aggaccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000929             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14370:15874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000929
VERSION     KCVT01000929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14370:15874"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78454.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agaacctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgaag tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagaatt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000930             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17418:9776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000930
VERSION     KCVT01000930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17418:9776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78455.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tattgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcatgg atagtgggga tgtaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac atctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacggatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtacagttt tggccagggg
      421 accagagtgg agatcaaacg ag
//
LOCUS       KCVT01000931             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10041:15405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000931
VERSION     KCVT01000931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10041:15405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78456.1"
                     /translation="CQHSYGTPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          115 c          109 g           98 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg cctctgctca
       61 gctcctaggg ctcctgctgc tctggctccc aggcgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtaggacaag
      181 tcagaacgtt aacaactatt tacattggta tcagcagaaa ccagggaaag cccctaggct
      241 cctgatctat gctgcgtcca atttgcaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactt tcaccatcac cagcctgcaa cctgaagatg ttgcaactta
      361 ttactgtcag catagttatg gtaccccgtt cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01000932             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15733:4859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000932
VERSION     KCVT01000932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15733:4859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78457.1"
                     /translation="CQQGNSIPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          115 c          107 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca attatttaaa ttggtatcag cagaaaccgg ggaaagcccc taaggtcctg
      241 atctattatg cagacagttt gtcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcaccctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagg gtaatagtat tccattcact ttcggccccg ggaccaaagt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01000933             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19843:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000933
VERSION     KCVT01000933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19843:10474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78458.1"
                     /translation="CMQALEFPLTF"
     J_segment       312..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           82 a           87 c          100 g           83 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagagt ccactctccc tgtccgtcac ccttggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgagatt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcacagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagtttc cgctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000934             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15706:7251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000934
VERSION     KCVT01000934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15706:7251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78459.1"
                     /translation="CMQALDFPYSF"
     J_segment       348..384
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           99 c          107 g           94 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac ctacagaagc
      181 caggccagtc tccacagctc ttgatttttg aggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacacta atttcacact gaaaatcagc agtgtggagg
      301 ctgaggatgt tggggtctat tactgcatgc aagctctaga ctttccttac agttttggcc
      361 aggggaccac agtggagatt aaacgag
//
LOCUS       KCVT01000935             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22938:4046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000935
VERSION     KCVT01000935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22938:4046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78460.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          118 c          112 g           87 t
ORIGIN      
        1 acatgggggc aggagccagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcaggatatt aacaactggt tggcctggta tcaacagaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca ttttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01000936             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14042:7438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000936
VERSION     KCVT01000936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14042:7438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78461.1"
                     /translation="CQQGSPFPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          112 c          107 g           95 t
ORIGIN      
        1 acatggggat gagcaaaact gacaagtcaa ggcaggaaga tgttgtctcc atcacaactc
       61 attgggtttc tgctgctctg ggttccagcc tccaagggtg aaattgtgct gactcagtct
      121 ccagcctttc ggtctgtgac tctaaaggag aaagtcacca tcacctgcca ggccagtcag
      181 agcattggta atagcttaca ctggtaccag cagaaaccgg atcagtctcc aaagctcctc
      241 atcaaatatg cttcccagtc catctcaggg gtcccctcaa ggttcagtgg cagtggatct
      301 gggacagatt tcaccctcac catcaacagc ctggaagctg aagatgctgc gacgtattac
      361 tgtcagcagg gaagtccttt cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01000937             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:4909:11573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000937
VERSION     KCVT01000937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4909:11573"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78462.1"
                     /translation="CMQGIDYPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          116 c          117 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gtcagtcacc cctggagagc cggccatctc ctgcagctct agtcagagcc
      181 tcttggatag tgaggatgga aacatctatt tggaatggta cctacagaag ccaggccagt
      241 ctccacagcc cttgatttat aaggtttcca cccgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcag cagagtggag cctgaggatg
      361 ttggggttta ttactgcatg caaggtatag actatccgta cagttttggc caggggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01000938             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:28848:10648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000938
VERSION     KCVT01000938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:28848:10648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78463.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000939             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:4970:7977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000939
VERSION     KCVT01000939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4970:7977"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78464.1"
                     /translation="CQQYDSDPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagacg gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagtcccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01000940             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22275:16702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000940
VERSION     KCVT01000940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22275:16702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78465.1"
                     /translation="CLQGYNIPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          110 c          111 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagtt gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gaaaagctcc taagcgcctg
      241 atctatgctg tgtccagttt ggaaggtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc gacttattac
      361 tgtctacagg gttataatat cccgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01000941             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12073:6621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000941
VERSION     KCVT01000941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12073:6621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78466.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01000942             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12796:10476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000942
VERSION     KCVT01000942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12796:10476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78467.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000943             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11919:19775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000943
VERSION     KCVT01000943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11919:19775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78468.1"
                     /translation="CQQYNSLYSF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          108 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagtag ttatttaaat tggtatcagc agaaaccggg ggaagcccct aagctcctga
      241 tctattatgt gaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tccaacctga ggattttgca acttattact
      361 gtcaacagta taatagttta tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000944             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12932:14161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000944
VERSION     KCVT01000944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12932:14161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78469.1"
                     /translation="CLQGYNIPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          110 c          111 g           98 t
ORIGIN      
        1 acatgggagg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccagt tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gtgtccagtt tggaaggtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtctacag ggttataata tcccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01000945             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24085:9606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000945
VERSION     KCVT01000945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24085:9606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78470.1"
                     /translation="CQHSFRTPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          107 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccgtcact tgcagggcta gtgagagcgt
      181 tagcaccaaa ttacattggt atcaacagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctggaac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt tttactgtca
      361 gcatagtttt cgtaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000946             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9616:4316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000946
VERSION     KCVT01000946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9616:4316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..318
                     /note="immunoglobulin light chain variable region"
     V_region        114..318
     V_segment       114..280
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78471.1"
                     /translation="CMQGLEFPITF"
     J_segment       283..318
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           70 a           84 c           89 g           78 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccaggcc
      121 agtctccaca gctcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      181 tcagtggcag tgggtcagac gctgatttca cactgagaat cagcagagtg gaggctgagg
      241 atgttggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      301 ccaaactgga gatcaaacga g
//
LOCUS       KCVT01000947             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11306:17285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000947
VERSION     KCVT01000947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11306:17285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78472.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          108 c           99 g          104 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccggacaa gtcaggatat
      181 tcacatttat ttaaattggt ttcagcagaa accagggaaa gtccctaaac tcctgatttc
      241 tgctgcatcc agtttggaaa gtgggttccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctggagat tttgcaattt attattgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000948             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16924:19583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000948
VERSION     KCVT01000948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16924:19583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78473.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagca tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaggctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000949             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7295:14982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000949
VERSION     KCVT01000949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7295:14982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78474.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          101 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccaatgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg gagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01000950             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:24293:18284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000950
VERSION     KCVT01000950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24293:18284"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78475.1"
                     /translation="CLQGDSTPFTF"
     J_segment       389..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          101 a          115 c          112 g           95 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gtaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccggg aaaagctcct aggcgcctaa
      241 tctatgctgc atccactttg gaaagtgggg tcccaccaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg tgatagtacc ccgttcactt ttggccaggg gaccaaagtg gacgtcaaac
      421 gag
//
LOCUS       KCVT01000951             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20103:14117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000951
VERSION     KCVT01000951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20103:14117"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78476.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          117 c          121 g          108 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacttgcaga aggcaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagcca ctgatttcaa actgaacatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000952             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:25004:14131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000952
VERSION     KCVT01000952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25004:14131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78477.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          109 t
ORIGIN      
        1 acatgggggt ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cactcttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttcctacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga agatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000953             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12405:18086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000953
VERSION     KCVT01000953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12405:18086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78478.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccgacag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000954             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21192:19130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000954
VERSION     KCVT01000954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21192:19130"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78479.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          117 c          110 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagtc
      181 agggtattaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaaactcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcggt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01000955             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8169:19985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000955
VERSION     KCVT01000955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8169:19985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78480.1"
                     /translation="CMQALDFPLTF"
     J_segment       313..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           80 a           92 c           99 g           81 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgcg gatgttgggg tttattactg catgcaagct
      301 ctagactttc ccctcacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000956             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14458:20726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000956
VERSION     KCVT01000956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14458:20726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78481.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtccttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagt agcagcttag cctggtacca acaaagacct gggcaggctc ccaggctcct
      241 catctatggt gcatccacca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gacgatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000957             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9767:14029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000957
VERSION     KCVT01000957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9767:14029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78482.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000958             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:26775:8532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000958
VERSION     KCVT01000958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:26775:8532"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78483.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgc ggacattgtg atgacccaga
      121 ctccactctc cctggccgtc actcttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggatcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000959             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8385:9826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000959
VERSION     KCVT01000959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8385:9826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78484.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01000960             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18038:9426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000960
VERSION     KCVT01000960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18038:9426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78485.1"
                     /translation="CVQAIAFPYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           92 a          119 c          122 g          101 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgccc atcacccctg gagagccggc ctccatctcc tgcaggtctg gtcagagcct
      181 cctgcatagt aatggaaaca cctatttgca ctggtacctg cagaagccag gccagtctcc
      241 gcagctcctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcaag ctatagcgtt tccgtacagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01000961             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10648:6354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000961
VERSION     KCVT01000961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10648:6354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..383
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78486.1"
                     /translation="CLQYSESPLSF"
     J_segment       388..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcgagtcaga
      181 ctattcgcag ttggttaaac tggtttcaac agaagtcagg aaaagcccct aaactcctga
      241 tctatagggc gtccatttta caaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcaacctga agattttgcg acttacttct
      361 gtctacagta tagtgagagc cctctctctt tcggcggggg gaccaaggtg gacattagac
      421 gag
//
LOCUS       KCVT01000962             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13263:7664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000962
VERSION     KCVT01000962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13263:7664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78487.1"
                     /translation="CMQAVEFPLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          107 t
ORIGIN      
        1 acatggggga ttgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct caatctcctg caggtctagt
      181 cagagcctcc tggatagtga ggatgggaac acctatttga catggtacct gaagaagcct
      241 ggccagtctc cacagctctt aatttatgag gtttccaatc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctgtagagt ttccgctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01000963             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:5773:9800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000963
VERSION     KCVT01000963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:5773:9800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78488.1"
                     /translation="CQQHNTYPLTF"
     J_segment       387..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          119 c          104 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccgggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 acattagtaa tgatttagcc tggtatcagc agaaaccagg gacagccccg aagcccctga
      241 tgtattacgc atccaatttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca agttattact
      361 gtcaacagca taatacttac ccattgactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01000964             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10179:18632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000964
VERSION     KCVT01000964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10179:18632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78489.1"
                     /translation="CMQALDFPYSF"
     J_segment       313..349
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           82 a           89 c           96 g           85 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctaca gaagccaggc cagtctccac agctcttgat ttttgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactaatttc
      241 acactgaaaa tcagcagtgt ggaggctgag gatgttgggg tctattactg catgcaagct
      301 ctagactttc cttacagttt tggccagggg accacagtgg agattaaacg ag
//
LOCUS       KCVT01000965             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15495:14750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000965
VERSION     KCVT01000965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15495:14750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78490.1"
                     /translation="CQHSFRTPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          115 c          111 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcaat gtcacttgca gggctagtga
      181 gagcgttagc accaaattac attggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcgtccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggaacagat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttttta
      361 ctgtcagcat agttttcgta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01000966             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:9103:11417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000966
VERSION     KCVT01000966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9103:11417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78491.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgtgat gacccagact
      121 ccactctccc tggccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 atcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01000967             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:3996:13819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000967
VERSION     KCVT01000967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:3996:13819"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78492.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          110 a          115 c          107 g           88 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcacagcc agtcaggata
      181 ttaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaaa ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcgaggtt cggtggaagt ggatctggga
      301 cagatttcac tctcaccatt agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01000968             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22594:13393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000968
VERSION     KCVT01000968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22594:13393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78493.1"
                     /translation="CMQALDFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          101 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccaatg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggttcct ggagaagcca
      241 ggccagtctc cacaactctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg ggatttatta ctgcatgcaa gctctagact ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01000969             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7581:17148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000969
VERSION     KCVT01000969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7581:17148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78494.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          127 c          120 g           88 t
ORIGIN      
        1 acatggtgag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01000970             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10421:10578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000970
VERSION     KCVT01000970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10421:10578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78495.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01000971             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16966:19790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000971
VERSION     KCVT01000971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16966:19790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78496.1"
                     /translation="CQQYNSDPRTF"
     J_segment       351..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           92 a          109 c          100 g           87 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcagggcatt cgcagttatt tagcgtggta tcagcagaaa
      181 ccagggaaac ccccgaagcc cttgatctat tacgcgtcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcaa cagtataaca gtgacccgcg cactttcggt
      361 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01000972             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14651:9103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000972
VERSION     KCVT01000972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14651:9103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..240
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78497.1"
                     /translation="CQQGYGFPFTF"
     J_segment       246..283
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           75 a           73 c           67 g           71 t
ORIGIN      
        1 acatggggag acacagtcgc gatcacttgc ctggcgagtc aaggcattgg caataattta
       61 aattggtatc agcagaaacc agggaaagcc cctaaactcc tgatctatac ggcatccaat
      121 ttacatggtg ggattccctc tcggttcagc ggcagtggat ctgggacgga tttcactctc
      181 accatcaaca gcctgcagcc tgaagatttt gccacttatt actgtcaaca gggttatggt
      241 tttccattca ctttcggccc cgggaccaaa ctggatatca aacgag
//
LOCUS       KCVT01000973             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18094:18525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000973
VERSION     KCVT01000973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18094:18525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78498.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ctattactgc atgcaagctc ttgagtttcc tctcactttc ggcgggggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01000974             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19585:19542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000974
VERSION     KCVT01000974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19585:19542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78499.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc ttggacgttc ggccaaggaa
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000975             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18174:3781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000975
VERSION     KCVT01000975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18174:3781"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78500.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggccgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01000976             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:27445:15951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000976
VERSION     KCVT01000976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:27445:15951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..433
                     /note="immunoglobulin light chain variable region"
     V_region        97..433
     V_segment       97..395
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78501.1"
                     /translation="CMQGLQTPYTF"
     J_segment       396..433
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT           94 a          119 c          119 g          104 t
ORIGIN      
        1 atgggggatc aggactcctc agttcacctt gtcacaatga ggctccctgc tcagctcctg
       61 gggctgctaa tgctctgggt ctctgcctcc agtggagata tcgtgatgac ccagactcca
      121 ctctcgctgc ccgtcaccct tggagagcca gcctccatct cctgcaggtc tagtcagagc
      181 cttctgaata gtaatggata cagctatttg agttggtacc tgcagaggcc aggccagtct
      241 ccacatctgc tgatctatta tggctctagt cgggcctccg gggtccccga caggttcagt
      301 ggcagtgggt caggcacaga ttttacactg aaaatcacca gggtggaggc tgacgacgta
      361 ggggtttatt actgcatgca aggtctacaa actccgtaca cttttggcca ggggaccaaa
      421 gtggagatca aacgag
//
LOCUS       KCVT01000977             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20553:18813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000977
VERSION     KCVT01000977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20553:18813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78502.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtggg gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01000978             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20043:20648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000978
VERSION     KCVT01000978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20043:20648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..365
                     /note="immunoglobulin light chain variable region"
     V_region        88..365
     V_segment       88..327
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78503.1"
                     /translation="CQQYDSDPRTF"
     J_segment       331..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           90 a           98 c          104 g           76 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagtc accatcactt gtcgggcgag
      121 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gagttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa cagtatgaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01000979             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17997:7423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000979
VERSION     KCVT01000979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17997:7423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78504.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01000980             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10694:7231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000980
VERSION     KCVT01000980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10694:7231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78505.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          116 c          105 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgttt
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01000981             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23717:15501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000981
VERSION     KCVT01000981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23717:15501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78506.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01000982             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17486:8026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000982
VERSION     KCVT01000982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17486:8026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..321
                     /note="immunoglobulin light chain variable region"
     V_region        1..321
     V_segment       1..283
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <261..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78507.1"
                     /translation="CQQYNSYPLTF"
     J_segment       284..321
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>324
                     /gene="IGKC"
BASE COUNT           82 a           86 c           79 g           77 t
ORIGIN      
        1 acatggggat gacccagtct ccatcctccc tgtctgcatc tgtgggagac acagtcacca
       61 tcacttgtcg ggcaagtcag gacattagca gttatttagc ctggtatcag cagaaaccag
      121 ggagagcccc taagcgcctg atctatgctg catcctcttt gcaaagtggg gtcccatcaa
      181 gcttcagcgg cagtggatct gggacagatt tcactctcac catcagcagc ctacagcctg
      241 aagattttgc aacttattac tgtcaacagt ataatagtta tccgctcact ttcggcggag
      301 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01000983             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25240:9968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000983
VERSION     KCVT01000983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25240:9968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78508.1"
                     /translation="CQQHDDSPRTF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          109 a          117 c          106 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcagcatca gcagcctgca gcctgaagat ttcgcacata ttactgtcaa
      361 cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01000984             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15238:15728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000984
VERSION     KCVT01000984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15238:15728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78509.1"
                     /translation="CMQALEFPYSF"
     J_segment       405..442
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctattgct ctggctccct ggatccactg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctca tggatagtgg ggatgtaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacatctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacacggat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgtacag ttttggccag
      421 gggaccagag tggagatcaa acgag
//
LOCUS       KCVT01000985             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:22355:17596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000985
VERSION     KCVT01000985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22355:17596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78510.1"
                     /translation="CQQHDNSPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          114 c          111 g           90 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat ctgtagggga cagagtcacc atcagttgta gagccagtca
      181 ggatataacc aactggctgg cctggtttca acagaaacca gggaaagccc ctaagctcct
      241 gatctatagg gcgtccaatt tgaaaacagg ggtcccatca aggttcagtg ggagtggatc
      301 tgggacacat ttcactctca ccatcaatcc tttgcagcct gaagatatcg gaacatatta
      361 ctgtcaacaa catgataact ccccgtggac attcggccaa gggacgaagg tggaagtcaa
      421 acgag
//
LOCUS       KCVT01000986             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7061:14653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000986
VERSION     KCVT01000986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7061:14653"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78511.1"
                     /translation="CQKYISPPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          130 c          106 g           91 t
ORIGIN      
        1 acatggggga gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caacttatat tgactcagtc
      121 tccagccacc ctgtctctgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccaggctcct
      241 cctctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtatatta
      361 ctgtcagaaa tatattagtc ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01000987             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20861:2621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000987
VERSION     KCVT01000987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20861:2621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78512.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          115 c          108 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 caccctgtct gcatctgaag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000988             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:28331:12594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000988
VERSION     KCVT01000988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28331:12594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78513.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatcaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggaat ttatttctgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01000989             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:26011:10223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000989
VERSION     KCVT01000989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26011:10223"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78514.1"
                     /translation="CLQFKTYPNSF"
     J_segment       385..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          118 c          104 g          100 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct aacctcctca
      241 tctatgctgc atccactttg gccggagggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tgcagcctga agattttgca acttattact
      361 gtctgcagtt taaaacttat ccgaacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01000990             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19358:5769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000990
VERSION     KCVT01000990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19358:5769"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78515.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggggatca
      421 aacgag
//
LOCUS       KCVT01000991             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7588:18737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000991
VERSION     KCVT01000991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7588:18737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78516.1"
                     /translation="CMQALEFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          125 c          115 g          106 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgata atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccattcacct tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01000992             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5550:11279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000992
VERSION     KCVT01000992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5550:11279"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78517.1"
                     /translation="CQQGNSIPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          113 c          107 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca ttacttgccg ggcaagtcag
      181 ggcattagca attatttaaa ttggtatcag cagaaaccgg ggaaagcccc aaaggtcctg
      241 atctattatg cagacagttt gtcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagg gtaatagtat tccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01000993             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13710:12012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000993
VERSION     KCVT01000993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13710:12012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78518.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          106 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagccttca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000994             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16234:11783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000994
VERSION     KCVT01000994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16234:11783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78519.1"
                     /translation="CMQALDFPYSF"
     J_segment       407..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          109 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tacagaagcc
      241 aggccagtct ccacagctct tgatttttga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactaa tttcacactg aaaatcagca gtgtggaggc
      361 tgaggatgtt ggggtctatt actgcatgca agctctagac tttccttaca gttttggcca
      421 ggggaccaca gtggagatta aacgag
//
LOCUS       KCVT01000995             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20488:4363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000995
VERSION     KCVT01000995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20488:4363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78520.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaacc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01000996             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10653:8295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000996
VERSION     KCVT01000996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10653:8295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78521.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagac
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01000997             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19505:15556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000997
VERSION     KCVT01000997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19505:15556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..365
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78522.1"
                     /translation="CLQGYNIPYNF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          110 c          112 g           97 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagttgacc cagtctccat
      121 cttccctgtc tgcatcggta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcgatta tttaagttgg tatcagcaga gaccaggaaa agctcctaag cgcctgatct
      241 atgctgtgtc cagtttggaa ggtggggtcc catcaagatt cggcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ctttgcgact ttttactgtc
      361 tacagggtta taatatcccg tacaattttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01000998             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:27937:11022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000998
VERSION     KCVT01000998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27937:11022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78523.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gttcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01000999             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19328:6369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01000999
VERSION     KCVT01000999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19328:6369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78524.1"
                     /translation="CVQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagcc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc gttcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001000             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24566:14723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001000
VERSION     KCVT01001000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24566:14723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78525.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcggaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001001             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:28359:12259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001001
VERSION     KCVT01001001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:28359:12259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78526.1"
                     /translation="CQQGNSIPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          115 c          105 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgtcccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattac caattattta aattggtatc agaagaaacc ggggaaagcc cctaaggtcc
      241 tgatctatta tgcagacagt ttgtcaactg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gggtaatagt attccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01001002             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17736:14305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001002
VERSION     KCVT01001002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17736:14305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78527.1"
                     /translation="CQQGYSFPFTF"
     J_segment       381..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           94 a          122 c          106 g           98 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcagtag tttaagctgg tatcagcaga aaccagggaa agcccctaac ctcctgatct
      241 ttagggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctcc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagtttcccc ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01001003             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4386:11728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001003
VERSION     KCVT01001003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4386:11728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..333
                     /note="immunoglobulin light chain variable region"
     V_region        3..333
     V_segment       3..296
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <273..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78528.1"
                     /translation="CMQALEFPLTF"
     J_segment       297..333
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        334..>336
                     /gene="IGKC"
BASE COUNT           78 a           85 c           93 g           80 t
ORIGIN      
        1 acatgggcca gactccactc tccctgcccg tcactcttgg agagccggcc tccatctcct
       61 gcaggtctag tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc
      121 tgcagaaacc aggccagtct ccacgactct tgatttatga ggtttccaac cgggcctctg
      181 gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca
      241 gagtggaggc tgaggatgtt ggggtttatt actgcatgca agctctagag tttcctctca
      301 ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001004             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12245:15918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001004
VERSION     KCVT01001004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12245:15918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78529.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           99 a          124 c          110 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtgatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01001005             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:4128:7953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001005
VERSION     KCVT01001005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4128:7953"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78530.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggatc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001006             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22653:7308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001006
VERSION     KCVT01001006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22653:7308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78531.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          122 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacatgt atttggactg gtacctacag aggccaggcc
      241 agtctcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgaattca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001007             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17019:4160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001007
VERSION     KCVT01001007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17019:4160"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78532.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          122 c          115 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagtgtagc ctggtaccgg caaaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001008             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23647:8785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001008
VERSION     KCVT01001008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23647:8785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78533.1"
                     /translation="CQENDNWPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           84 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagtcacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagtttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatcat gcatccacca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcaggag aacgataact ggcctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001009             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11242:20387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001009
VERSION     KCVT01001009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11242:20387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78534.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          123 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggatcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001010             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11666:11904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001010
VERSION     KCVT01001010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11666:11904"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78535.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          116 g           85 t
ORIGIN      
        1 acatggggga ggtactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatctt gcactttatt
      361 actgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccgag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001011             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14029:6652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001011
VERSION     KCVT01001011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14029:6652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78536.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagcggggat ggaaacatct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001012             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6253:13233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001012
VERSION     KCVT01001012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6253:13233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78537.1"
                     /translation="CQQHADSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          119 c          113 g           89 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcagggtatt agcaactggt tggcctggta tcaacagaga ccagggaaag cccctaaggt
      241 cctgatttat aggacatcca atttggaaac aggggtccca tcaaggttca gtggaaccgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt tcgctacata
      361 ttactgtcaa cagcatgctg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001013             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14716:19266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001013
VERSION     KCVT01001013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14716:19266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78538.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          115 c          103 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctgagc tcctgattta
      241 tgttacatcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001014             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14308:6775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001014
VERSION     KCVT01001014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14308:6775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    214..367
                     /note="immunoglobulin light chain variable region"
     V_region        214..367
     V_segment       214..330
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78539.1"
                     /translation="CMQPLEFPWTF"
     J_segment       331..367
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           79 a          101 c          104 g           86 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccggtctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtc ccagacaggt tcagtggcag
      241 tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt
      301 ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggac caaggtggaa
      361 atcaaacgag
//
LOCUS       KCVT01001015             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:27429:20566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001015
VERSION     KCVT01001015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:27429:20566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78540.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          120 c          108 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattgc
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001016             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16519:4376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001016
VERSION     KCVT01001016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16519:4376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78541.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001017             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15455:17891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001017
VERSION     KCVT01001017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15455:17891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78542.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          118 c          112 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc cctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcaggatatt aacaactggt tggcctggta tcaacagaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca ttttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001018             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24832:15392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001018
VERSION     KCVT01001018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24832:15392"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78543.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgagc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001019             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:11110:10124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001019
VERSION     KCVT01001019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11110:10124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78544.1"
                     /translation="CQQYDSDPFTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          102 a          115 c          107 g           94 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 tatgcgtcca ctttggaatc tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtatgaca gtgacccgtt cactttcggt ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01001020             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15985:4878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001020
VERSION     KCVT01001020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15985:4878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78545.1"
                     /translation="CQQGYSYHPTF"
     J_segment       386..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>423
                     /gene="IGKC"
BASE COUNT           94 a          119 c          109 g          101 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga cttccttatg acgcagtctc
      121 cttcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gtgagtcaag
      181 ccattggcac taatttaaat tggtatcagc agagaccagg aaaagcccct aaactcctga
      241 tctatagggc ttccggtttg cagagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cagtctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac catcccactt tcggcggagg gaccaaggtg gagatccaac
      421 gag
//
LOCUS       KCVT01001021             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7757:8390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001021
VERSION     KCVT01001021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7757:8390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78546.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          121 c          116 g          108 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccacagtg gagattaaac gag
//
LOCUS       KCVT01001022             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15753:6181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001022
VERSION     KCVT01001022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15753:6181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78547.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          119 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgaa tccagtgggg acattgtgat gacgcagact
      121 ccatactccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctactcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt ctcagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggttg agatcaaacg ag
//
LOCUS       KCVT01001023             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13393:11492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001023
VERSION     KCVT01001023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13393:11492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78548.1"
                     /translation="CQQNDNWARTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          122 c          118 g           83 t
ORIGIN      
        1 acatggggga gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agacaccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtcct tgtctccagg agaaagagcc accctctcct gtagggccag
      181 tcagagtgtc agcagcagtt tagcctggta ccagcagaaa cctggacagg ctcccaggct
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcagttta
      361 ttattgtcag cagaatgata actgggctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001024             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21435:18077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001024
VERSION     KCVT01001024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21435:18077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78549.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtgcggac attgtgatga cccagactcc
      121 actctccctg gccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggat
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001025             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10025:8880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001025
VERSION     KCVT01001025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10025:8880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..397
                     /note="immunoglobulin light chain variable region"
     V_region        79..397
     V_segment       79..363
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78550.1"
                     /translation="CYQHSSGYSF"
     J_segment       364..397
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>400
                     /gene="IGKC"
BASE COUNT           93 a          118 c          108 g           81 t
ORIGIN      
        1 acatgggcag aaggaaccat ggaagcccca gctcagcttc tctgccttct gctactctgg
       61 ctcccaggta ccaccggaca agttatattg acacagtctc cagccaccct gtctttgtct
      121 ccaggggaaa gagccactct ctcctgcagg gccagtcaga gtgttagcag ctacttagcc
      181 tggtaccagc agaaacctgg gcaggctccc aggctcctca tccacagtgc gtccagcagg
      241 gccactggca tcccagacag gttcagtggc agtgggtctg ggacagagtt caccctcacc
      301 atcagcagcc tggagcctga agatgttgga gtttatcact gctatcagca tagcagcggg
      361 tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01001026             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15240:8341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001026
VERSION     KCVT01001026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15240:8341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78551.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001027             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11220:2890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001027
VERSION     KCVT01001027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11220:2890"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78552.1"
                     /translation="CMQGLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggtt ggagacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtgt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc ttggacattc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001028             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:26724:6012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001028
VERSION     KCVT01001028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26724:6012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78553.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          104 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgtaactt attactgtca
      361 acaacataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001029             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12542:20321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001029
VERSION     KCVT01001029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12542:20321"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78554.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgagt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001030             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17227:4834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001030
VERSION     KCVT01001030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17227:4834"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..412
                     /note="immunoglobulin light chain variable region"
     V_region        94..412
     V_segment       94..376
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78555.1"
                     /translation="CYQHSRGWAF"
     J_segment       377..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>415
                     /gene="IGKC"
BASE COUNT           97 a          121 c          115 g           82 t
ORIGIN      
        1 acatgggggc taggttagta cccagaagga accatggaag ccccagctca gcttctctgc
       61 cttctgctac tctggctccc aggtaccacc ggacaaatta tattgacaca gtctccagcc
      121 accctgtctt tggcaccagg ggaaagagcc actctctcct gcagggccag tgagaatgtt
      181 ggcagctact tagcctggta ccagcagaac cctgggcagg ctcccaggct cctcgtccac
      241 agtgcgtcca gcagggccac tgacatccca gacaggttca gtggcagtgg gtctcggaca
      301 gagttcaccc tcaccatcag cagtctggag cctgaagatg ttggagtcta ttactgctat
      361 caacatagca gggggtgggc gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01001031             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11227:24684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001031
VERSION     KCVT01001031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11227:24684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78556.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cccaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001032             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:8353:9566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001032
VERSION     KCVT01001032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8353:9566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..377
                     /note="immunoglobulin light chain variable region"
     V_region        80..377
     V_segment       80..330
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78557.1"
                     /translation="CQQHNGYPPTF"
     J_segment       343..377
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>380
                     /gene="IGKC"
BASE COUNT           95 a          108 c           95 g           82 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattacga atgatttagc
      181 ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg atctattacg catcaaggtt
      241 cagcggcagt ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga
      301 ttttgcaact tattattgtc aacagcataa tggataccct ccgacgttcg gccaagggac
      361 cagggtggaa atcaaacgag
//
LOCUS       KCVT01001033             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17000:2845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001033
VERSION     KCVT01001033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17000:2845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78558.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gggggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001034             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5200:19595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001034
VERSION     KCVT01001034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5200:19595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78559.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 attttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001035             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15768:20025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001035
VERSION     KCVT01001035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15768:20025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..383
                     /note="immunoglobulin light chain variable region"
     V_region        44..383
     V_segment       44..345
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78560.1"
                     /translation="CMQPLEFPWTF"
     J_segment       346..383
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           87 a           97 c          112 g           90 t
ORIGIN      
        1 acatggggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
       61 gactccactg tccctgcccg tcacccttgg agagccggcc tccatctcct gtgggtctag
      121 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      181 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      241 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      301 tgaggatgtt ggggtttatt actgcatgca acctctagag tttccgtgga cgttcggcca
      361 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001036             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17283:14195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001036
VERSION     KCVT01001036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17283:14195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78561.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc actcttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaaaccag
      241 gccagtctcc acgactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001037             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19626:6515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001037
VERSION     KCVT01001037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19626:6515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78562.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcgg aagccaggcc
      241 agtctccaca gctcctcatt tatgaggttt ccaaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actcaattca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatgaaacga g
//
LOCUS       KCVT01001038             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20077:5844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001038
VERSION     KCVT01001038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20077:5844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78563.1"
                     /translation="CQQGYNYPWTF"
     J_segment       379..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          110 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatctct tgccaggcga gtcaaggcat
      181 tgacaataat ttaagttggt ttcagcagac accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat aattacccgt ggacgttcgg ccaggggacc aaggtggaga tccaacgag
//
LOCUS       KCVT01001039             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6588:5727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001039
VERSION     KCVT01001039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6588:5727"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78564.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           92 a          120 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgctgg tctagtcaga
      181 gcctcttgga tagtgaggat gggaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcagacga g
//
LOCUS       KCVT01001040             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16674:7635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001040
VERSION     KCVT01001040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16674:7635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78565.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001041             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:26619:12067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001041
VERSION     KCVT01001041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26619:12067"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78566.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          115 c          105 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001042             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23882:4335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001042
VERSION     KCVT01001042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23882:4335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78567.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          103 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcaacagaa accaggaaaa gcccctgaag tcctgatcta
      241 tagggcatcc agtttgcaaa gtggctttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001043             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8278:17036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001043
VERSION     KCVT01001043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8278:17036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..365
                     /note="immunoglobulin light chain variable region"
     V_region        88..365
     V_segment       88..323
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78568.1"
                     /translation="CQQYDSDSLTF"
     J_segment       328..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           92 a           97 c          100 g           79 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagtc accatcactt gtcgggcgac
      121 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01001044             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18011:16381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001044
VERSION     KCVT01001044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18011:16381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78569.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          123 c          114 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctt tggatcccag ataccgccgg agaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttccta gcctggtacc agcagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgcattcttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001045             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17312:12612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001045
VERSION     KCVT01001045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17312:12612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78570.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          106 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatgtct tgccgggcaa gtcagggtat
      181 tagcagctct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001046             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21317:13642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001046
VERSION     KCVT01001046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21317:13642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78571.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga catcgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atctggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01001047             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:6519:12986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001047
VERSION     KCVT01001047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6519:12986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78572.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          114 c          112 g           93 t
ORIGIN      
        1 acatggggag aaccactcgg gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggcag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001048             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22806:10767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001048
VERSION     KCVT01001048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22806:10767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78573.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          115 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ctagtgggga tgttgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gcccttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001049             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:27800:8994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001049
VERSION     KCVT01001049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:27800:8994"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78574.1"
                     /translation="CQQGYSYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          119 c          109 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgcaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattggca atactttaaa ttggtatcaa cagaaaccgg ggaaagcccc tacactcctg
      241 atctataggg catccggttt gcaaagtggg actccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta tccgtacagt tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001050             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15711:7838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001050
VERSION     KCVT01001050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15711:7838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    186..370
                     /note="immunoglobulin light chain variable region"
     V_region        186..370
     V_segment       186..333
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <310..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78575.1"
                     /translation="CMQALEFPLTF"
     J_segment       334..370
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>373
                     /gene="IGKC"
BASE COUNT           77 a          106 c           98 g           92 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttga tttatgaggt ttccaatcgg gcctctggtc tcccagacag gttcagtggc
      241 agtgggtcag acactgattt cacactgaaa atcagcagag tggagcctga ggatgttggg
      301 gtttattact gcatgcaagc tctagaattt cctctcactt tcggtggagg gaccaaggtg
      361 gagatcaaac gag
//
LOCUS       KCVT01001051             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:8761:9104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001051
VERSION     KCVT01001051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:8761:9104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78576.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          108 c          110 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gagttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001052             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18534:9932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001052
VERSION     KCVT01001052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18534:9932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..382
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78577.1"
                     /translation="CCQYSSGSSF"
     J_segment       384..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           94 a          123 c          116 g           88 t
ORIGIN      
        1 acatggggag agctgctagg ttagtaccca gagggaacca tggaagcccc agctcggctt
       61 ctctgccttc tgctactctg gctcccaggt accaccggac aagttatatt gacacagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccactc tctcctgcag ggccagtcag
      181 agtgttagca ctcacttagc ctggtaccag cagaaacctg gtcaggctcc caggctcctc
      241 atccacagtg cgtccagcag ggccactggc atcccagaca ggttcagtgg cagcgggtct
      301 gggacagagt tcaccctcac catcagcagc ctggagcctg aagatgttgg agtttatcac
      361 tgctgtcagt atagtagcgg gtccagtttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01001053             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17110:17881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001053
VERSION     KCVT01001053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17110:17881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78578.1"
                     /translation="CQQSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          118 c          104 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tctaggagac agcgtcacca tcacttgcag gacaagtgcg
      181 agcgttaata actatttaca ttggtatcag cggaaaccag ggaaagcccc tgaactcctg
      241 atctatgctg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggaacagatt tcactctcac catcagcagc ctgcagtctg aagatgttgc aacttattac
      361 tgtcagcaaa gttatgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001054             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12994:7698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001054
VERSION     KCVT01001054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12994:7698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78579.1"
                     /translation="CQQYDSDTRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           90 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccacttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgaca cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001055             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17513:3914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001055
VERSION     KCVT01001055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17513:3914"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78580.1"
                     /translation="CMQGLEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcctgtcacc cttggagagc cggcctccat ctcctgcaga tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct acttggaatg gtacctgcag aagtcaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001056             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15768:19682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001056
VERSION     KCVT01001056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15768:19682"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78581.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca ggtcttaatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001057             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9014:7120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001057
VERSION     KCVT01001057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9014:7120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78582.1"
                     /translation="CQQYDSDPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gtcccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01001058             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18755:13886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001058
VERSION     KCVT01001058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18755:13886"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78583.1"
                     /translation="CQQYNSFPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          110 c          107 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctctag gggacagagt caccattact tgccgggcaa ctcagggcgt
      181 tagtggttat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acaatataat agttttcctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001059             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13693:19070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001059
VERSION     KCVT01001059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13693:19070"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78584.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca cccttagaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaggccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggg agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001060             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:27813:10166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001060
VERSION     KCVT01001060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27813:10166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..433
                     /note="immunoglobulin light chain variable region"
     V_region        97..433
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78585.1"
                     /translation="CMQALEFPYTF"
     J_segment       400..433
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>439
                     /gene="IGKC"
BASE COUNT           95 a          119 c          117 g          108 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagagtcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagacc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctcctcaac tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca acagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctt acacttttgg ccaggggacc
      421 acagtggaga tcatacgag
//
LOCUS       KCVT01001061             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13953:12365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001061
VERSION     KCVT01001061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13953:12365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78586.1"
                     /translation="CMQTLEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          120 c          123 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccggtggg gacattgtga tgacccaggc
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatggtgagg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaaac tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001062             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22784:8165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001062
VERSION     KCVT01001062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22784:8165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78587.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01001063             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14526:14720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001063
VERSION     KCVT01001063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14526:14720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78588.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaaatgggg tcccatcaag gttcagcgcc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001064             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16814:8115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001064
VERSION     KCVT01001064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16814:8115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..279
                     /note="immunoglobulin light chain variable region"
     V_region        11..279
     V_segment       11..237
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78589.1"
                     /translation="CQQYDSDSLTF"
     J_segment       242..279
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>282
                     /gene="IGKC"
BASE COUNT           75 a           68 c           75 g           64 t
ORIGIN      
        1 acatggggag agtcaccatc acttgtcggg cgactcagga cattcgcagt tatttagcgt
       61 ggtatcagca gaaaccagga aaagccccga ggcccttgat ctattacgcg tccactttgg
      121 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca
      181 tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacaatat gacagtgatt
      241 cgctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001065             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5955:19663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001065
VERSION     KCVT01001065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5955:19663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78590.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaca aatagtgctg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccagc agaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccagcagg gccactggca tcccaggcag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa cagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001066             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15430:13058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001066
VERSION     KCVT01001066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15430:13058"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78591.1"
                     /translation="CQQHNSYPLTF"
     J_segment       383..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>422
                     /gene="IGKC"
BASE COUNT          105 a          121 c          107 g           89 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 gattaccaat gatttagcct ggtatcagca gacaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaaatggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatttcgcaa cttattactg
      361 tcaacagcat aatagttacc cactcacttt cggcggaggg accaaggtgg agatcagacg
      421 ag
//
LOCUS       KCVT01001067             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20924:17183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001067
VERSION     KCVT01001067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20924:17183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78592.1"
                     /translation="CHQHNSFPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           99 a          108 c          105 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctgggactcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagaa acagtcaccg tcacttgtcg ggcaagtcgg ggcgttagta atgatttagc
      181 ctggtatcag cagaaaccag ggaaagcccc gaggcccctg atctattatg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 aatcagcagc ctgcagcctg aagattttgc aacttattac tgtcaccaac ataatagttt
      361 cccgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01001068             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9779:8894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001068
VERSION     KCVT01001068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9779:8894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78593.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          116 c          110 g           88 t
ORIGIN      
        1 acatgggagg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 ggatattaac aactggttgg cctggtatca acagaaacca gggaaagccc ctaaggtcct
      241 gatctatagg gcatccattt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001069             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10813:3770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001069
VERSION     KCVT01001069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10813:3770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78594.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaagtgga tatcaaacga g
//
LOCUS       KCVT01001070             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:8414:7182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001070
VERSION     KCVT01001070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8414:7182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78595.1"
                     /translation="CQQHADSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          118 c          111 g           90 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcactttca gagccagtca
      181 gggtattagc aactggttgg cctggtatca acagagacca gggaaagccc ctaaggtcct
      241 gatttatagg acatccaatt tggaaacagg ggtcccatca aggttcagtg gaaccggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg ctacatatta
      361 ctgtcaacag catgctgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001071             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15416:9219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001071
VERSION     KCVT01001071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15416:9219"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78596.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttatagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtgggag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001072             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6778:17151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001072
VERSION     KCVT01001072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6778:17151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..401
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78597.1"
                     /translation="CMQSTKDPLTF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          124 c          109 g          107 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc atcttctcac gatgagactc cctgctcagc
       61 tcctcgggct gttgatgctc tgggtccctg gatccagtgg cgatattttg atgacccaga
      121 ctccactctc gctgcccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 aaagccttct gcatagtaat ggatacacct atttgcattg gtacctgcag aagccaggcc
      241 agtctccacg tctcctgatc tataaagtta ccaatcggga atctggggtc ccagacaggt
      301 tcagcggcag tgggtcaggc atagatttca cactgaaaat cagcagggtg gagcctgagg
      361 atgttggtgt ttattactgc atgcaaagta caaaagatcc cctcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001073             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14041:5651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001073
VERSION     KCVT01001073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14041:5651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..343
                     /note="immunoglobulin light chain variable region"
     V_region        10..343
     V_segment       10..305
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <283..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78598.1"
                     /translation="CLQSKNSPWTF"
     J_segment       306..343
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>346
                     /gene="IGKC"
BASE COUNT           87 a           88 c           92 g           79 t
ORIGIN      
        1 acatgggggg acattgtgct gacccagtct ccagcctctt tggccgtgtc tccagggcag
       61 agggccacca tcacctgcag agccagtgag agtgtcagtt tgtttggaat aagcctcatt
      121 cactggtatc agcagaaacc aggacaacct cctaaactcc tgatttacca agcattcaat
      181 acagagactg gggtcccagt caggttcagc ggcagtgggt ctgggaccga tttcaccctc
      241 acaattaatc ctgtggaagc tgacgatgct gcagattatt tctgtctgca gagtaagaat
      301 tctccgtgga cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001074             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24619:3763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001074
VERSION     KCVT01001074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24619:3763"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78599.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgagc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001075             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12780:10651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001075
VERSION     KCVT01001075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12780:10651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78600.1"
                     /translation="CQQHNTYPTTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagt ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atgtattacg catccaattt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagact tcactctcac catcagcagt ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatactta ccctaccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001076             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11736:10703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001076
VERSION     KCVT01001076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11736:10703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78601.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001077             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16947:5651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001077
VERSION     KCVT01001077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16947:5651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78602.1"
                     /translation="CQQDFDWPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagctcca gcacagcttc
       61 tcttcctcct gctactctgg atcccagata ccaccggaga agttgtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcaa caccttaacc tggtaccagc acaaacctgg gcaggctccc aagctcctcc
      241 tctatggtgc atccaccagg gcctccggca tcccaggcag gttcagtgcc agtgggtctg
      301 gaacagagtt tactctcacc atcagcagcc tggagcctga agatgttgga atttattact
      361 gtcagcagga ttttgactgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001078             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13539:10326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001078
VERSION     KCVT01001078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13539:10326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78603.1"
                     /translation="CLQGYSAPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          120 c          104 g           97 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcttc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcc attatttaag ttggtatcaa cagaaaccag gaaaaactcc tcagcgcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gttatagtgc cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01001079             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:10971:10167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001079
VERSION     KCVT01001079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10971:10167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78604.1"
                     /translation="CQQHDNSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          118 c          109 g           89 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgttacatc cagatgaccc agtctccatc
      121 ctccctctct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtgt
      181 tagcgactgg ttggcctggt atcaacagag accagggaaa gcccctaaac tcctgatcta
      241 tagggcgtcc aatttggata caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgctacat attactgtca
      361 acagcatgat aattcccctc cgacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001080             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15317:14609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001080
VERSION     KCVT01001080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15317:14609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78605.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcgt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaag tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccggacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001081             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5265:11343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001081
VERSION     KCVT01001081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5265:11343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78606.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001082             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23918:8902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001082
VERSION     KCVT01001082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23918:8902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78607.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cattctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctggag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001083             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6657:12293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001083
VERSION     KCVT01001083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6657:12293"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78608.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          109 c          107 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001084             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14914:17965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001084
VERSION     KCVT01001084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14914:17965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78609.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aaaccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga ggtcaaacga g
//
LOCUS       KCVT01001085             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:23371:12020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001085
VERSION     KCVT01001085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23371:12020"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78610.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 ggacattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001086             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:25877:6855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001086
VERSION     KCVT01001086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25877:6855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78611.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          119 c          106 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccttc
      121 ctccctgtct gcatctgtag gagacacaat caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagac accaggtaga gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01001087             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19707:11165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001087
VERSION     KCVT01001087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19707:11165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78612.1"
                     /translation="CMPALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcttagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgccagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001088             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18407:15891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001088
VERSION     KCVT01001088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18407:15891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78613.1"
                     /translation="CHQHNSFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          114 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga aacagtcacc gtcacttgtc gggcaagtcg
      181 gggcgttagt aatgatttag cctggtatca gcagaaacca gggaaagccc cgaggcccct
      241 gatctattat gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca caatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaccaa cataatagtt tcccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001089             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20467:14838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001089
VERSION     KCVT01001089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20467:14838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78614.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc aaaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001090             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8419:4591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001090
VERSION     KCVT01001090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8419:4591"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78615.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          109 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca ggggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001091             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13757:10732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001091
VERSION     KCVT01001091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13757:10732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78616.1"
                     /translation="CLQYRSYPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          105 g           96 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 tagcagttat ttaaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtatagg agttacccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001092             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18630:6195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001092
VERSION     KCVT01001092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18630:6195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..299
                     /note="immunoglobulin light chain variable region"
     V_region        4..299
     V_segment       4..261
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <239..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78617.1"
                     /translation="CMQPLEFPWTF"
     J_segment       262..299
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>302
                     /gene="IGKC"
BASE COUNT           73 a           71 c           88 g           70 t
ORIGIN      
        1 acatggggag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga
       61 tggaaacacc tatttggaat ggtacctcca gaagccaggc cagtctccac atctcttgat
      121 ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      181 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      241 catgcaacct ctagagtttc cgtggacgtt cggccagggg accaaggtgg aaatcaaacg
      301 ag
//
LOCUS       KCVT01001093             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:5915:3811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001093
VERSION     KCVT01001093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:5915:3811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..379
                     /note="immunoglobulin light chain variable region"
     V_region        108..379
     V_segment       108..341
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78618.1"
                     /translation="CQQYDSDPFTF"
     J_segment       344..379
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>382
                     /gene="IGKC"
BASE COUNT           96 a          100 c          104 g           82 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag agtcaccatc
      121 acttgtcggg cgagtcaggg cattcgcagt tatttagcgt ggtatcagca gaaaccaggg
      181 aaagccccga aggccttgat ctattacgcg tccactttgg aaagtggggt cccatcaagg
      241 ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa
      301 gattttgcaa cttattactg tcaacagtat gacagtgacc cgttcacttt cggtggaggg
      361 accaaggtag agatcaaacg ag
//
LOCUS       KCVT01001094             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14435:8694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001094
VERSION     KCVT01001094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14435:8694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78619.1"
                     /translation="CMQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tacaatttcc gtggacgttc gaccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001095             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:26753:6163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001095
VERSION     KCVT01001095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26753:6163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..391
                     /note="immunoglobulin light chain variable region"
     V_region        100..391
     V_segment       100..354
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78620.1"
                     /translation="CQQNSNWPLTF"
     J_segment       355..391
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT           96 a          118 c          101 g           79 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagagt tcactctcac catcagcagc
      301 ctggagcctg aagatgttgc actttattat tgtcagcaga atagtaactg gcctctcact
      361 ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001096             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:9885:17909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001096
VERSION     KCVT01001096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9885:17909"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78621.1"
                     /translation="CLQESNWSYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat agtaccggag aaatagtggt gacacagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcaaaa gcaggttagc ctggtaccag cagaaacctg ggcaagctcc caggctcctc
      241 atgtatgatg cgtccagcag ggccactggc atcccagaca ggttcactgg cagcgggtct
      301 gggccagagt tcactctcac catcagcagc ctggagcctg aagatgttgc ggtttatttc
      361 tgtcttcagg agagtaactg gtcgtacagc tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001097             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9977:19224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001097
VERSION     KCVT01001097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9977:19224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78622.1"
                     /translation="CLQFKPYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           95 a          118 c          105 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa ccttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001098             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18499:21098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001098
VERSION     KCVT01001098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18499:21098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    71..392
                     /note="immunoglobulin light chain variable region"
     V_region        71..392
     V_segment       71..350
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78623.1"
                     /translation="CQQYDSDSLTF"
     J_segment       355..392
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>395
                     /gene="IGKC"
BASE COUNT           95 a          108 c          101 g           91 t
ORIGIN      
        1 acatggggac atgagggtcc ccgctcagct cctaggactc ctgctgctct gtctcccagg
       61 tgccaaatgt gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga
      121 cagagtcacc atcacttgtc gggcgactca ggacattcgc agttatttag cgtggtatca
      181 gcagaaacca gggaaagccc cgaagccctt gatctattac gcgtccactt tggaaagtgg
      241 ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag
      301 cctgcagcct gaagattttg caacttatta ctgtcaacag tatgacagtg attcgctcac
      361 tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01001099             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:12070:13681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001099
VERSION     KCVT01001099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12070:13681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78624.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccca gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01001100             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20556:7027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001100
VERSION     KCVT01001100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20556:7027"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..265
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78625.1"
                     /translation="CQQYNSDPFTF"
     J_segment       266..303
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>306
                     /gene="IGKC"
BASE COUNT           79 a           76 c           78 g           73 t
ORIGIN      
        1 acatgggctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
       61 agggcgttag aagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      121 tgatttatta cgcatccatt ttggaaggtg gggtcccatc aaggtttagc ggcagtggat
      181 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      241 actgtcagca gtataacagt gacccattca ctttcggccc cgggaccaaa ctggatatca
      301 aacgag
//
LOCUS       KCVT01001101             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18972:4025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001101
VERSION     KCVT01001101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18972:4025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..433
                     /note="immunoglobulin light chain variable region"
     V_region        97..433
     V_segment       97..395
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78626.1"
                     /translation="CMQSIKDPFTF"
     J_segment       396..433
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          100 a          120 c          111 g          105 t
ORIGIN      
        1 acatggggga gggactcctc agttcatctt ctcacgatga gactccctgc tcagctcctc
       61 gggctgttga tgctctgggt ccctggatcc agtggggata ttgtgatgac ccagacccca
      121 ctctcggtgc ccgtcacccc tggagagccg gcctccatct cctgcaggtc tagtcaaagc
      181 cttctccata gtaatggaga cacctattta cattggtacc ttcagaggtc aggccagtct
      241 ccacggctcc tgatctataa agtaaccaat cggctacctg gggtcccaga caggttcagt
      301 ggcagtgggt caggcacaga tttcacactg aaaatcagca gggtggagcc tgaggatatt
      361 ggtgtttatt tctgcatgca aagtataaaa gatccattca ctttcggccc cgggaccaaa
      421 ctggatatca aacgag
//
LOCUS       KCVT01001102             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22375:17088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001102
VERSION     KCVT01001102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22375:17088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78627.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca acagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001103             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12412:6470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001103
VERSION     KCVT01001103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12412:6470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78628.1"
                     /translation="CQQHDDSPRTF"
     J_segment       389..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          114 a          119 c          106 g           88 t
ORIGIN      
        1 acatggggca ggagtcagtc tcagacagga cacagcatgg acacgagggt ccccgctcag
       61 ctcctggggc tcctgttgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg cagagccagt
      181 cacgatatta acaactggtt ggcctggtat caacagaaac cagggaaagc ccctaaggtc
      241 ctgatctata gggcatccaa tttggaaaca ggggtcccat caaggttcag tggaagtggt
      301 tctgggacag atttcactct caccatcaac aacctgcagc ctgaagatat cgcaacatat
      361 tactgtcaac aacatgatga ttcccctcgg accttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01001104             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18517:10367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001104
VERSION     KCVT01001104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18517:10367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78629.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          124 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccatcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001105             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25752:13114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001105
VERSION     KCVT01001105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25752:13114"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78630.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001106             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11442:14152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001106
VERSION     KCVT01001106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11442:14152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78631.1"
                     /translation="CLQGYIIPYNF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          110 c          110 g          100 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg gaaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg gcttattatt
      361 gtctacaggg ttatattatc ccgtacaatt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001107             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12244:12411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001107
VERSION     KCVT01001107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12244:12411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78632.1"
                     /translation="CQQYNSLPLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          108 a          110 c          112 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg catctctggg ggacagagtc accatcactt gccgggcaag
      181 tcaggacatt agcagatatt taaattggta tcagcagaaa ccggggaaag cccctaagtt
      241 cctgatctat tatgtaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta
      361 ttattgtcaa cagtataata gtttaccgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01001108             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13742:7272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001108
VERSION     KCVT01001108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13742:7272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78633.1"
                     /translation="CHQHNSFPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaaa cagtcaccgt cacttgtcgg gcaagtcggg
      181 gcgttagtaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aggcccctga
      241 tctattatgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcaca atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaccaaca taatagtttc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001109             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22831:15230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001109
VERSION     KCVT01001109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22831:15230"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78634.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           97 a          117 c          118 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca ctggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccttcac ctgcagagcc agtgggagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcagca gaaaccagga caacctccta
      241 aactcctgat ttatcaagca agcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac gatgctgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01001110             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21966:14493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001110
VERSION     KCVT01001110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21966:14493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78635.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001111             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12361:6566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001111
VERSION     KCVT01001111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12361:6566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78636.1"
                     /translation="CQQYNSLPLSF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          109 c          106 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatgc aaaccgttta gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacttga agattttgca acttattact
      361 gtcaacaata taatagttta ccgctctctt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001112             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21899:19062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001112
VERSION     KCVT01001112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21899:19062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78637.1"
                     /translation="CQQYDSDSLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          110 a          122 c          116 g           98 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca acctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtatgacagt gattcgctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001113             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14350:6028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001113
VERSION     KCVT01001113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14350:6028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78638.1"
                     /translation="CQQHNTYPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          118 c          106 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaaacccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatactta cccgtacact tttggccagg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001114             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5146:14330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001114
VERSION     KCVT01001114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5146:14330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78639.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          118 c          117 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga aaccaggcca
      241 gtctccacga ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001115             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6702:12525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001115
VERSION     KCVT01001115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6702:12525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78640.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacacagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001116             357 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21272:14238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001116
VERSION     KCVT01001116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21272:14238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..354
                     /note="immunoglobulin light chain variable region"
     V_region        33..354
     V_segment       33..317
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <294..>326
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78641.1"
                     /translation="CQQHDNSPPTF"
     J_segment       320..354
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        355..>357
                     /gene="IGKC"
BASE COUNT           95 a           92 c           90 g           80 t
ORIGIN      
        1 acatggggag tctcagacag ggtgccagat gtgacatcca gatgacccag tctccttcct
       61 ccctgtctgc atctataggc gacagagtca ccatcacttg cagagccagt cagggtatta
      121 gcgactggtt ggcctggtat caacagaaac cagggaaagc ccctaaactc ctgatctata
      181 gggcatccaa tttggaaaca ggggtcccat caaggttcag tggaagtgga tctgggacag
      241 atttcactct caccatcagc agcctgcagg ctgaagattt cgcaacatat ttctgtcaac
      301 agcatgataa ttcccctccc actttcggtg gagggactaa ggtggagatc aaacgag
//
LOCUS       KCVT01001117             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8336:11004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001117
VERSION     KCVT01001117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8336:11004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78642.1"
                     /translation="CYQHSRGWAF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           95 a          124 c          116 g           83 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggcacc accggacaag ttatgttgac acagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccactctct cctgcagggc cagtgagaat
      181 gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccagcagggc cactgacatc ccagacaggt tcagtggcag tgggtctcgg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttggagt ctattactgc
      361 tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01001118             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25287:7792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001118
VERSION     KCVT01001118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25287:7792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78643.1"
                     /translation="CQQYNSLPLTF"
     J_segment       364..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           97 a          108 c          103 g           96 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccgtcctccc tgtctgcttc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag ggcattagca gttttttaaa
      181 ttggtatcga cagaaaccgg ggaaaccccc taacctcctg atctattatg caaaccgttt
      241 ggaaagtggg gtcccttcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaacctg aagattttgc aacttattac tgtcaacagt ataatagttt
      361 accgctcact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001119             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16274:11657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001119
VERSION     KCVT01001119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16274:11657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78644.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tggtgaagat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001120             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25376:5735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001120
VERSION     KCVT01001120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25376:5735"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78645.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctttgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001121             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19517:16956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001121
VERSION     KCVT01001121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19517:16956"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78646.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001122             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16372:15508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001122
VERSION     KCVT01001122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16372:15508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78647.1"
                     /translation="CQQYNSDPFTF"
     J_segment       381..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          109 a          117 c          101 g           94 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtaaccatca cttgtcgggc gagtcaggac
      181 ataagaagtt atttagcgtg gtatcagcag aaaccaggca aacccccgaa gcccttgatc
      241 tattacgcat ccgttttgga aagtggggtc ccatcaaggt tcagtggcag tggatctggg
      301 acagaattca ctctcaccat cagcagtctg cagcctgagg attttgcaac ttattactgt
      361 caacaatata acagtgaccc attcactttc ggccccggga ccaaactgga taccaaacga
      421 g
//
LOCUS       KCVT01001123             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:8253:13439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001123
VERSION     KCVT01001123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8253:13439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78648.1"
                     /translation="CQQYNSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          113 c          103 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagcagaa accaggaaaa gccccgaagg ccttgatcta
      241 ttacgcatcc attttagaaa atgcggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca gcagcctgca atctgacgat tttgcaactt attactgtca
      361 acagtataac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001124             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15309:15718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001124
VERSION     KCVT01001124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15309:15718"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78649.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          116 c           98 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatctt
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01001125             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20299:17736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001125
VERSION     KCVT01001125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20299:17736"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78650.1"
                     /translation="CQQYDSDPYSF"
     J_segment       385..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>425
                     /gene="IGKC"
BASE COUNT          105 a          112 c          114 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtt gggcgagtca
      181 gggcattagg agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac acatccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgtacag ttttggccag gggaccagag tggagatcca
      421 acgag
//
LOCUS       KCVT01001126             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21291:13945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001126
VERSION     KCVT01001126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21291:13945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78651.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01001127             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12974:12551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001127
VERSION     KCVT01001127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12974:12551"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78652.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          119 c          106 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001128             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11213:17601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001128
VERSION     KCVT01001128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11213:17601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78653.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           95 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01001129             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10992:5624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001129
VERSION     KCVT01001129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10992:5624"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78654.1"
                     /translation="CMQALEFPYTF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagagtcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagac
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctcctcaa ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tacacttttg gccaggggac
      421 cacagtggag atcaaacgag
//
LOCUS       KCVT01001130             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25828:18838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001130
VERSION     KCVT01001130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25828:18838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78655.1"
                     /translation="CQQYDSDLFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           95 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatttg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc tgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001131             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17605:16396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001131
VERSION     KCVT01001131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17605:16396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78656.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          120 c          111 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accctcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tggcgtggta tcaccagaaa ccagggaaag ccccgaaacc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcac cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacccgtt cactttcggt ggagggacca aggtagagat
      421 caaacgag
//
LOCUS       KCVT01001132             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:26148:15461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001132
VERSION     KCVT01001132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:26148:15461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78657.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          108 c          107 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gaggttctcc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taacagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001133             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16367:6760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001133
VERSION     KCVT01001133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16367:6760"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..247
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78658.1"
                     /translation="CQQHDDSPRTF"
     J_segment       249..284
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           84 a           71 c           72 g           60 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg cacagccagt cagggtatta ataactggtt
       61 ggcctggtat caacagaaac caggaaaagc ccctaaactc cttatctata gggcatccaa
      121 tttggaaaca ggggtcccat cgaggttcgg tggaagtgga tctgggacag atttcactct
      181 caccatcagc agcctgcagc ctgaagatat cgcaacatat ttctgtcaac agcatgatga
      241 ttcccctcgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01001134             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10060:16169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001134
VERSION     KCVT01001134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10060:16169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78659.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagac ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001135             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:4925:13717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001135
VERSION     KCVT01001135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4925:13717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78660.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001136             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13420:9315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001136
VERSION     KCVT01001136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13420:9315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..389
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78661.1"
                     /translation="CQQFNNLPPTF"
     J_segment       392..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>429
                     /gene="IGKC"
BASE COUNT          106 a          112 c          114 g           97 t
ORIGIN      
        1 acatggggag gaggagtcag acccagtcag gacacagcat ggacatgagg gtccccgctc
       61 agctcctggg gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc
      121 agtctccatc ctccctgtct gcttctggag gagacagtgt caccatcagt tgccgggcaa
      181 gtcaggacat tagcatttat ttaaattggt ttcagcagaa accggggaaa gcccctaagc
      241 tcctgatcta tgatggaaac cgtttggaga ctggggtccc atcaaggttc agcggcagtg
      301 gatccgggac agaattcact ctcaccatca ccagcctgca acctgaagat tttggaactt
      361 attactgtca acagtttaat aatttacctc ccactttcgg cggagggacc aaggtggaga
      421 tcaaaggag
//
LOCUS       KCVT01001137             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22792:17344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001137
VERSION     KCVT01001137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22792:17344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78662.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001138             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:3151:8691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001138
VERSION     KCVT01001138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3151:8691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78663.1"
                     /translation="CMHTLEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca ggtcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcatactc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001139             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12731:10501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001139
VERSION     KCVT01001139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12731:10501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..440
                     /note="immunoglobulin light chain variable region"
     V_region        98..440
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78664.1"
                     /translation="CMQALEFPPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          124 c          113 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagaatcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattattgca tgcaagctct agagtttcct ccattcactt tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01001140             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16366:2738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001140
VERSION     KCVT01001140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16366:2738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78665.1"
                     /translation="CMQALEFPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcaacaga gtggaggctg
      361 aggatgttgg gttttattat tgcatgcaag ctctagagtt tcctcccact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001141             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20925:13399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001141
VERSION     KCVT01001141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20925:13399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78666.1"
                     /translation="CLQYNSSPLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          118 c          113 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acatagcatg gacatgaggg tccctgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacacagtc accatcactt gccgggcgag
      181 tcagactatt agcagctggt tagactggta tcagcagaaa ccagggaaag cccctaacct
      241 cctgatcttt aaggcatcca gtttgcaaag tggggtcccc tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttattgtcta cagtacaata gtagcccgct cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01001142             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13259:7327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001142
VERSION     KCVT01001142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13259:7327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78667.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001143             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26830:6059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001143
VERSION     KCVT01001143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26830:6059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78668.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagct ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001144             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16356:16997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001144
VERSION     KCVT01001144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16356:16997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78669.1"
                     /translation="CLQGDTSPFSF"
     J_segment       390..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          114 c          113 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagccag
      181 gacattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atctatgctg catccagttt ggagagtggg gtcccatcta ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg aggattttgc aacttattac
      361 tgtctacagg gtgatacttc cccgtttagt ttcggcggag ggacccaggt ggtgatcaaa
      421 cgag
//
LOCUS       KCVT01001145             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20836:13924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001145
VERSION     KCVT01001145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20836:13924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78670.1"
                     /translation="CMQGLEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat agaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaaggtc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001146             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21171:12821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001146
VERSION     KCVT01001146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21171:12821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78671.1"
                     /translation="CHQYSSGFTF"
     J_segment       381..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           92 a          131 c          109 g           88 t
ORIGIN      
        1 acatggggga gctgctaggt tagtacccag aaggaaccat ggaagcccca gctcagcttc
       61 tctgccttct gctactctgg ctcccaggta ccaccggtca agttatactg acacagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccactct ctcctgcagg gccagtcaga
      181 gtgttagcag ttccttagcc tggtaccagc agaaacctgg gcaggctccc aggctcctca
      241 tccacagtgc gtccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagaatt caccctcacc atcagcagcc tggagcctga ggatgttgga ctttatcact
      361 gccatcagta cagcagcggc ttcactttcg gccccgggac caaactggat ttcaaacgag
//
LOCUS       KCVT01001147             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9308:20248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001147
VERSION     KCVT01001147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9308:20248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78672.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcacctta acctggtacc accagaagcc tgggcaggct cccaagctcc
      241 tcatctatgg tccatccatc agggccagcg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga atttattctc accatcagca gcctggagac tgaagatgtt ggagtttatt
      361 actgtcagca ggattatcac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001148             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:9501:10225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001148
VERSION     KCVT01001148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:9501:10225"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78673.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtgcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001149             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19944:4410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001149
VERSION     KCVT01001149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19944:4410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78674.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          112 c          117 g           92 t
ORIGIN      
        1 acatgggggg gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tctccatctc ctgccaagcc agagcagatg
      181 tacatggtga aatatcttgg atccggataa accttgaaca aagacttgaa ccccatttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagaccggtt catcagcaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01001150             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10671:10838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001150
VERSION     KCVT01001150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10671:10838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..384
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78675.1"
                     /translation="CQQHNSYPRTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt accagatgtg acatccagat gacccagtct
      121 ccatcttcct tgtctgcatc tgtaggagac agagtcacca tcacttgcca agccagtcag
      181 ggtattggca actggttagc ctggtatcgg cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg catccagttt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcagcagc ataatagtta tcctcggacg ttcggccaag ggaccaaggt ggaaatcaag
      421 cgag
//
LOCUS       KCVT01001151             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17053:10378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001151
VERSION     KCVT01001151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17053:10378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..365
                     /note="immunoglobulin light chain variable region"
     V_region        88..365
     V_segment       88..327
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78676.1"
                     /translation="CQQYNSDPFTF"
     J_segment       328..365
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           98 a           99 c           92 g           79 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagta accatcactt gtcgggcgag
      121 tcaggacata agaagttatt tagcgtggta tcagcagaaa ccaggcaaac ccccgaagcc
      181 cttgatctat tacgcatccg ttttggaaag tggggtccca tcaaggttca gtggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagtctgcag cctgaggatt ttgcaactta
      301 ttactgtcaa caatataaca gtgacccatt cactttcggc cccgggacca aactggatac
      361 caaacgag
//
LOCUS       KCVT01001152             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7604:2534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001152
VERSION     KCVT01001152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7604:2534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78677.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggaggc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01001153             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9232:15246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001153
VERSION     KCVT01001153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9232:15246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78678.1"
                     /translation="CQHGYGIPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagtcccag tcaggacaca gcatggacat gagggccccc actcagctcc
       61 tggggttcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccag gcgagtcagg
      181 ccattagtaa taatgtaatc tggtatcagc aggaaccggg gaaagcccct aagctcctga
      241 tctataaggc atccacttta caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcagcatgg ttatggtatc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001154             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:4423:15435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001154
VERSION     KCVT01001154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4423:15435"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78679.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          116 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcagcct cccaggctcc
      241 tcatttatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaggatgtt gcagtttatt
      361 attgtcagca aaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001155             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22643:6660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001155
VERSION     KCVT01001155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22643:6660"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78680.1"
                     /translation="CQQHDNSPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          119 c          111 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct ctctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 gtgttagcga ctggttggcc tggtatcaac agagaccagg gaaagcccct aaactcctga
      241 tctatagggc gtccaatttg gatacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgct acatattact
      361 gtcaacagca tgataattcc cctccgacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001156             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17353:11793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001156
VERSION     KCVT01001156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17353:11793"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78681.1"
                     /translation="CMQGLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          117 c          126 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcccttgga tccagtgggg acattgtgat gacccagact
      121 ccgctctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgaggt tggagacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtg tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001157             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:4723:16869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001157
VERSION     KCVT01001157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4723:16869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78682.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          127 c          109 g           88 t
ORIGIN      
        1 acatggagag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccggt gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca ccacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001158             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23973:17542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001158
VERSION     KCVT01001158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23973:17542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78683.1"
                     /translation="CQQYDSDPFTF"
     J_segment       375..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          102 a          113 c          106 g           92 t
ORIGIN      
        1 acatgggcag tcaggacaca gcatggacat gagggtcccc gctcagctcc taggactcct
       61 gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc catcctccct
      121 gtctacatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg gcattcgcag
      181 ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga tctattacgc
      241 gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcagcctga agattttgca acttattact gtcaacagta
      361 tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac gag
//
LOCUS       KCVT01001159             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24909:12670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001159
VERSION     KCVT01001159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24909:12670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78684.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          100 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccagtct ccctgcccgt cacccttaga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct acagaggcca
      241 ggccagtctc cacagctctt aatttatgag gtttcctacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01001160             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:7332:2130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001160
VERSION     KCVT01001160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:7332:2130"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78685.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          119 c          120 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgga gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001161             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11358:13385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001161
VERSION     KCVT01001161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11358:13385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78686.1"
                     /translation="CMQPLDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc agccttggag agccggcctc cattttctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaac ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01001162             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18119:6798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001162
VERSION     KCVT01001162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18119:6798"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78687.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagtcac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001163             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20846:19902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001163
VERSION     KCVT01001163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20846:19902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78688.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctctatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01001164             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13329:18520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001164
VERSION     KCVT01001164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13329:18520"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78689.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          128 c          112 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacagacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcgct gccagtgggt
      301 ctggaacaga ctttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001165             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13756:9888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001165
VERSION     KCVT01001165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13756:9888"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78690.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          123 c          114 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tgaaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01001166             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12719:7600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001166
VERSION     KCVT01001166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12719:7600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78691.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          120 c          105 g           91 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaacat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001167             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20689:13368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001167
VERSION     KCVT01001167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20689:13368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78692.1"
                     /translation="CQQYNSYPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          118 c          105 g           96 t
ORIGIN      
        1 acatggggaa tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcag ttatttagcc tggtatcagc agaaaccagg gaaagcccct aagcgcctga
      241 tctatgctgc atccacttta caaagtgggg tcccatcaag cttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tacagcctga agattttgca acttattact
      361 gtcaacagta taatagttat ccgctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001168             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19837:9575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001168
VERSION     KCVT01001168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19837:9575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78693.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga cccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaggccagg
      241 ccagtctcca cagctcttga tttttgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001169             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12136:18744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001169
VERSION     KCVT01001169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12136:18744"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    52..373
                     /note="immunoglobulin light chain variable region"
     V_region        52..373
     V_segment       52..326
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>345
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78694.1"
                     /translation="CQQHNGYPPTF"
     J_segment       339..373
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        374..>376
                     /gene="IGKC"
BASE COUNT          101 a          102 c           92 g           81 t
ORIGIN      
        1 acatggggag gagtcagaac cactcagctc tggctcccag gtgccagatg tgacatccag
       61 atgacccagt ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt
      121 cgggcaagtc agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc
      181 ccgaagcccc tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc
      241 ggcagtggat ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt
      301 gcaacttatt attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg
      361 gtggaaatca aacgag
//
LOCUS       KCVT01001170             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14351:18830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001170
VERSION     KCVT01001170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14351:18830"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78695.1"
                     /translation="CLQYKSFPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          112 a          117 c           97 g           98 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtgggagac actgtcacca tcacttgccg gacaagtcaa
      181 ggtattacca attatttaca ttggtttcaa cagaaaccag ggaaagcccc taaactcctg
      241 atctatgaaa catccagttt gacaagtggg gtcccatcaa ggttcagcgg cagcgcatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaagttt cccgtacact tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001171             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24124:12556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001171
VERSION     KCVT01001171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24124:12556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78696.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          124 c          111 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg aaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01001172             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16502:4645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001172
VERSION     KCVT01001172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16502:4645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78697.1"
                     /translation="CQQVLTNPAF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          113 c          106 g           99 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccaggtg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag gaatttagcg tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctatgctgc atccagattg caaagtgggt ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcaacc tacagcctga agattctgca atttattact
      361 gtcaacaggt tcttactaac ccggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001173             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20247:11606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001173
VERSION     KCVT01001173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20247:11606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78698.1"
                     /translation="CQQGHSYPLTF"
     J_segment       386..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          121 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccg tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca aaagtttaag ttggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctataggg catccaattt acaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gtcatagtta cccactcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01001174             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7735:7091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001174
VERSION     KCVT01001174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7735:7091"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78699.1"
                     /translation="CQQYNSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtcggaga cagagtcacc atcacttgtc gggcgagtca
      181 ggacattcgc agttacttag cgtggtatca gcagagacca gggaaagccc cgaagccctt
      241 gatctactac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001175             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20718:16531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001175
VERSION     KCVT01001175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20718:16531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78700.1"
                     /translation="CQQHNNYSPTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          119 c          106 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccac
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttagcaatga tttagcctgg tatcagctga aaccagggaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagcataa taattactct cccactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001176             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21100:17308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001176
VERSION     KCVT01001176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21100:17308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78701.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacctgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01001177             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22607:17908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001177
VERSION     KCVT01001177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22607:17908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78702.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          111 c          109 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgttc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001178             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20700:12387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001178
VERSION     KCVT01001178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20700:12387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78703.1"
                     /translation="CQQYHSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          111 c          107 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gtattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aacctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca aattatttct
      361 gtcaacagta tcatagtcta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001179             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21327:6650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001179
VERSION     KCVT01001179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21327:6650"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78704.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          116 c          108 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattaacaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaggtcctga
      241 tctataggac atccattttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001180             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24444:19419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001180
VERSION     KCVT01001180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24444:19419"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78705.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          102 g          102 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg ttccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc tcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggtttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacttgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001181             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18926:16107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001181
VERSION     KCVT01001181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18926:16107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..460
                     /note="immunoglobulin light chain variable region"
     V_region        121..460
     V_segment       121..423
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <400..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78706.1"
                     /translation="CMQALEFPWTF"
     J_segment       424..460
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>463
                     /gene="IGKC"
BASE COUNT          104 a          125 c          126 g          108 t
ORIGIN      
        1 acatgggtca acgcagagta catggggact gatcacgact cctcaggtca ccttctcaca
       61 atgaggctcc ctgctcagct cctgggactg ctaatgctct ggctccctgg atccagtggg
      121 gacattgtga tgacccagac tccactctcc ctgcccgtca cccttggaga gccggcctcc
      181 atctcctgca ggtctagtca gagcctcttg gatagtgagg atggaaacac ctatttggat
      241 tggtacctgc agaagccagg ccagtctcca cacctcttga tttatgaggt ttccaaccgg
      301 gcctctggag tcccagacag gttcagtggc agtgggtcag acactgattt cacactgaaa
      361 atcagcagag tggaggctga ggatgttggg gtttattact gcatgcaagc tctagagttt
      421 ccttggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001182             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:25323:9115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001182
VERSION     KCVT01001182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25323:9115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78707.1"
                     /translation="CMQSLEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctaatttcac actgagaatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001183             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11973:13924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001183
VERSION     KCVT01001183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11973:13924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78708.1"
                     /translation="CLQYKSYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          113 c           97 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggttat
      181 tatcaattat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgattta
      241 tgctgcatcc agattggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01001184             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:5972:18216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001184
VERSION     KCVT01001184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5972:18216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78709.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacatct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001185             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17431:19508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001185
VERSION     KCVT01001185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17431:19508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78710.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          125 c          112 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcagactc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001186             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19746:17939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001186
VERSION     KCVT01001186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19746:17939"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78711.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttgggat tttttattgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001187             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17686:18413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001187
VERSION     KCVT01001187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17686:18413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78712.1"
                     /translation="CHQYNNLPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          113 c          103 g           97 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 attaacattt atttaaattg gtatcagcag aaaccgggga aagcccctaa gctcctgatc
      241 tattatgcaa atcgtttgga aactggggtc ccgtcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat caacagcctg caacccgaag attttgcaac ttattactgt
      361 caccagtata ataatttacc actcactttc ggcggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01001188             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5428:12868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001188
VERSION     KCVT01001188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5428:12868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78713.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 ttccaatgat ttagcctggt atcagcagag accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01001189             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:24618:15809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001189
VERSION     KCVT01001189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24618:15809"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78714.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgttcactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001190             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21077:8356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001190
VERSION     KCVT01001190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21077:8356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78715.1"
                     /translation="CQQYNSDPRTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           90 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataaca gtgacccgcg cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01001191             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11239:19714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001191
VERSION     KCVT01001191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11239:19714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78716.1"
                     /translation="CQQHDNSPPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagtctca gacagggcac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccttcctccc tgtctgcatc tataggcgac agagtcacca tcacttgcag agccagtcag
      181 ggtattagcg actggttggc ctggtatcaa cagaaaccag ggaaagcccc taaactcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcaggctg aagatttcgc aacatatttc
      361 tgtcaacagc atgataattc ccctcccact ttcggtggag ggactaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001192             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12555:3674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001192
VERSION     KCVT01001192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12555:3674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..343
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78717.1"
                     /translation="CQQYDSDSLTF"
     J_segment       348..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           93 a          107 c           98 g           90 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgac tcaggacatt cgcagttatt tagcgtggta tcagcagaaa
      181 ccagggaaag ccccgaagcc cttgatctat tacgcgtcca ctttggaaaa tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcaa cagtatgaca gtgattcgct cactttcggt
      361 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01001193             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14878:15685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001193
VERSION     KCVT01001193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14878:15685"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78718.1"
                     /translation="CMQAREFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          127 c          113 g          103 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggagg ggaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgctggggtt tattactgca tgcaagctcg agagtttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01001194             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11348:9560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001194
VERSION     KCVT01001194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11348:9560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..375
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78719.1"
                     /translation="CQQGYTYLYNF"
     J_segment       383..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          115 c          103 g          100 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgttggagac acagtcacca tcacttgcca ggcgagtcaa
      181 gccattgcca ataatttaaa ttggtatcag cagaaaccag gaaaagcccc taaagtccta
      241 atctataagg catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatactta cctgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001195             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6663:5995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001195
VERSION     KCVT01001195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6663:5995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78720.1"
                     /translation="CQQYDSDPFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           93 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgaccc gttcactttc ggtggaggga ccaaggtaga gatcaaacga
      421 g
//
LOCUS       KCVT01001196             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10521:5716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001196
VERSION     KCVT01001196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10521:5716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78721.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          107 t
ORIGIN      
        1 acatggggtc tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggaaattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttggag agccggccac catctcctgc aggtctagtc
      181 agagcctctt ggctagtgag gatggaaaca cctatttgga gtggttcctg cagaagccag
      241 gccagtctcc acacctcttg atttatgacg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001197             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13046:7631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001197
VERSION     KCVT01001197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13046:7631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78722.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacatct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001198             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17691:6730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001198
VERSION     KCVT01001198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17691:6730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78723.1"
                     /translation="CLQYKSYPFTF"
     J_segment       388..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          109 a          115 c          101 g          103 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag
      181 tcaggttatt atcaattatt taaattggtt tcagcagaaa ccagggaaag cccctaagct
      241 cctgatttat gctgcatcca gattggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtataaaa gttacccatt cactttcggc cccgggacca aactggatat
      421 caaacgag
//
LOCUS       KCVT01001199             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23046:9259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001199
VERSION     KCVT01001199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23046:9259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78724.1"
                     /translation="CQHSYGTPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          114 c          106 g           98 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtagga caagtcagaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagccccta ggctcctgat
      241 ctatgctgcg tccaatttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actttcacca tcaccagcct gcaacctgaa gatgttgcaa cttattactg
      361 tcagcatagt tatggtaccc cgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001200             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21446:14517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001200
VERSION     KCVT01001200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21446:14517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..392
                     /note="immunoglobulin light chain variable region"
     V_region        56..392
     V_segment       56..354
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78725.1"
                     /translation="CMQGLQTPYTF"
     J_segment       355..392
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>395
                     /gene="IGKC"
BASE COUNT           86 a          106 c          110 g           93 t
ORIGIN      
        1 acatggggct cagctcctgg ggctgctaat gctctgggtc tctgcctcca gtggagatat
       61 cgtgatgacc cagactccac tctcgctgcc cgtcaccctt ggagagccag cctccatctc
      121 ctgcaggtct agtcagagcc ttctgaatag taatggatac agctatttga gttggtacct
      181 gcagaggcca ggccagtctc cacatctgct gatctattat ggctctagtc gggcctccgg
      241 ggtccccgac aggttcagtg gcagtgggtc aggcacagat tttacactga aaatcaccag
      301 ggtggaggct gacgacgtag gggtttatta ctgcatgcaa ggtctacaaa ctccgtacac
      361 ttttggccag gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01001201             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16358:6937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001201
VERSION     KCVT01001201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16358:6937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78726.1"
                     /translation="CLQGYIDPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          113 c          111 g           99 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac ttccagatga cccagtctcc
      121 atcttccctg tctgcatcgg tcggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tttttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat
      241 ttatgctgca tccagtttgc aaagtggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcgg cttattactg
      361 tctacagggt tatattgacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001202             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16996:15105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001202
VERSION     KCVT01001202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16996:15105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78727.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          121 c          116 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 cttctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag tttactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001203             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:22226:16674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001203
VERSION     KCVT01001203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22226:16674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78728.1"
                     /translation="CQQYNYLPRTF"
     J_segment       387..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>425
                     /gene="IGKC"
BASE COUNT          106 a          115 c          109 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagt caatatttaa attggtatca gcagaaaccg gggaaagccc ctaacctcct
      241 catctattat gtaaaccgtt tggaaagtgg ggtcccatca cggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaggactttg caacttatta
      361 ctgtcagcag tataattatt tacctcggac gttcggccaa gggaccaagg tggaaatcgg
      421 acgag
//
LOCUS       KCVT01001204             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21100:17926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001204
VERSION     KCVT01001204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21100:17926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78729.1"
                     /translation="CQQYNSDPRTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          115 c          113 g           91 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcagcatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgctact tattactgtc
      361 aacagtataa cagtgacccg cgcactttcg gtggagggac cagggtggag atcaaacgag
//
LOCUS       KCVT01001205             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25785:15028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001205
VERSION     KCVT01001205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25785:15028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78730.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacgt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01001206             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18385:19000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001206
VERSION     KCVT01001206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18385:19000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..230
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78731.1"
                     /translation="CQQYDSDSLTF"
     J_segment       235..272
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>275
                     /gene="IGKC"
BASE COUNT           72 a           66 c           73 g           64 t
ORIGIN      
        1 acatgggacc atcacttgtc gggcgactca ggacattcgc agttatttag cgtggtatca
       61 gcagaaacca gggaaagtcc cgaagccctt gatctattac gcgtccactt tggaaagtgg
      121 ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag
      181 cctgcagcct gaagattttg caacttatta ctgtcaacag tatgacagtg attcgctcac
      241 tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01001207             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:25084:13553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001207
VERSION     KCVT01001207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25084:13553"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78732.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc tcagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001208             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10159:18386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001208
VERSION     KCVT01001208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10159:18386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78733.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001209             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14717:7960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001209
VERSION     KCVT01001209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14717:7960"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78734.1"
                     /translation="CQQYNSLPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          109 a          111 c          110 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctc cttctgtcgg agacagagtc accatcactt gccgggcaag
      181 tcaggtcatt aggagttatt taaattggta tcagcagaaa ccggggaaag cccctaaact
      241 cctgatctat tatgtaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagact ttggaactta
      361 ttactgtcaa cagtataata gtttaccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01001210             265 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18284:18076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001210
VERSION     KCVT01001210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 265)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18284:18076"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..265
                     /note="immunoglobulin light chain variable region"
     V_region        8..265
     V_segment       8..246
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78735.1"
                     /translation="CQKYSSSPFTF"
     J_segment       247..265
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           57 a           75 c           78 g           55 t
ORIGIN      
        1 acatgggggg gaaagagcca ccctctcctg cagggccagt cagagtgttg gcagcagctt
       61 agcctggtac cagcagaaac ctgggcaggc ccccagactc ctcgtctatg gtgcatccag
      121 gagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcactct
      181 caccatcagc agcctggagc ctgaagattt tgcagtgtat tactgtcaga agtatagtag
      241 ttccccattc actttcggcc ccggg
//
LOCUS       KCVT01001211             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13039:12479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001211
VERSION     KCVT01001211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13039:12479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78736.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccagttt ggaaagtggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaag tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01001212             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:10762:8306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001212
VERSION     KCVT01001212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10762:8306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78737.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001213             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8863:8063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001213
VERSION     KCVT01001213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8863:8063"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78738.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca tccttggaga gccggcctcc atatcctgca cgtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattatt gcatgcaagc tctagagttt ccgctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001214             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5266:20075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001214
VERSION     KCVT01001214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5266:20075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78739.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          123 c          124 g           97 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg ctagagagga tggaaacacc tatttggact ggtacctgca gaggccaggc
      241 cagactcccc agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 gtcagaggca gtgggtcaga cactgagttc acactgaaaa tcagcagagt ggaggctgag
      361 gatcttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001215             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22188:10122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001215
VERSION     KCVT01001215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22188:10122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78740.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaggctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001216             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21529:10588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001216
VERSION     KCVT01001216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21529:10588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78741.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactgtccc tgcccgtcac ccttggagag ccggcctcca tctcctgtgg gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001217             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20970:19790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001217
VERSION     KCVT01001217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20970:19790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78742.1"
                     /translation="CQQGYYTPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          118 c          116 g           91 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcgtc cctgtctgct tctgtaggag acaaagtcac catcacttgc cgagccagtc
      181 aggatattag cagctggtta gcctggtatc agcagaaacc agggaaagcc cctagactcc
      241 tgatctataa ggcgtccact ttggcaagtg gggtcccatc aaccttcagc ggcagtgggt
      301 ctgggacgga ttacactctc accatcagca ggctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gggttactat accccgtgga cgttcggcca ggggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001218             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20449:8768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001218
VERSION     KCVT01001218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20449:8768"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78743.1"
                     /translation="CQQYNSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          112 c          113 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001219             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8898:17902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001219
VERSION     KCVT01001219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8898:17902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78744.1"
                     /translation="CQQYNSLPFSF"
     J_segment       386..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          105 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcac ttttttaaat tggtatcagc agataccggg gaaagcccct aaactcctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tgcaacctga ggattttgca acttattcct
      361 gtcaacagta taatagttta ccgttcagtt ttggccaggg gaccacagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001220             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14117:11340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001220
VERSION     KCVT01001220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14117:11340"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78745.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001221             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9368:12140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001221
VERSION     KCVT01001221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9368:12140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78746.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          120 c          116 g           89 t
ORIGIN      
        1 atgggggaag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcagtag tccggagcct gcggatgttg gactttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001222             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20833:16568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001222
VERSION     KCVT01001222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20833:16568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78747.1"
                     /translation="CMQALEFPYSF"
     J_segment       405..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga gtggcacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgacg tttccagccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccctacagt tttggccagg
      421 ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01001223             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16910:14083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001223
VERSION     KCVT01001223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16910:14083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78748.1"
                     /translation="CQQHNVYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          120 c          108 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagc ctggtatcag cagagaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatgttta ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001224             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:9993:8843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001224
VERSION     KCVT01001224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:9993:8843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78749.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacacg gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001225             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16091:10863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001225
VERSION     KCVT01001225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16091:10863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78750.1"
                     /translation="CYQYTGGYTF"
     J_segment       384..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           93 a          127 c          112 g           88 t
ORIGIN      
        1 acatggggga gctgctaggt tagtacccag agggaaccat ggaagcccca gctcggcttc
       61 tctgccttct gctactctgg ctcccaggta ccaccggaca agttatattg acacagtctc
      121 cagccaccct gtctttgtct ccaggggaga gagccactct ctcctgcagg gccagtcaga
      181 gtgttagtac ttacttagcc tggtaccagc agaaacctgg gcaggctccc aggctcctca
      241 tccacagtgc gtccagcagg gccactggca tcccagacag gttcagtggc agcgggtctg
      301 ggacagagtt caccctcacc atcagcagcc tggagcctga agatgttgga gtttatcact
      361 gctatcagta taccggcgga tacactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01001226             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14762:4548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001226
VERSION     KCVT01001226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14762:4548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78751.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          112 c          117 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tctccatctc ctgccaagcc agagcagatg
      181 tacatggtga aatatcttgg atccggataa accttgaaca aagacttgaa ccccatttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagaccggtt catcagcaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtgggg atcaaacgaa
//
LOCUS       KCVT01001227             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13368:10774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001227
VERSION     KCVT01001227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13368:10774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..374
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78752.1"
                     /translation="CQQHDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          117 c          106 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 gtattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctta
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatatttct
      361 gtcaacagca tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001228             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18185:7042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001228
VERSION     KCVT01001228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18185:7042"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78753.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           96 a          126 c          111 g           93 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg aaaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacatccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgctttcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001229             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20471:12118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001229
VERSION     KCVT01001229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20471:12118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78754.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatctagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgaag tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01001230             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14050:12917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001230
VERSION     KCVT01001230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14050:12917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..432
                     /note="immunoglobulin light chain variable region"
     V_region        95..432
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78755.1"
                     /translation="CMQSLDFPLTF"
     J_segment       397..432
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>437
                     /gene="IGKC"
BASE COUNT           94 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gttatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacacag atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc agtctctaga ttttccgctc accttcggtg gagggaccaa
      421 ggtggagatc aatcgag
//
LOCUS       KCVT01001231             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15409:7449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001231
VERSION     KCVT01001231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15409:7449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78756.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          122 c          115 g           87 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccag cagaaacctg ggcaggctcc caggctcctc
      241 atctttggta catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001232             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18724:9058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001232
VERSION     KCVT01001232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18724:9058"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78757.1"
                     /translation="CQQSYRYPLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatgtatctt gcatccactt tgcagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctcg ccatcaacag cctgcagcct gaagatgctg caacttatta
      361 ctgtcagcag agttatcgtt atccgctcac tttcggtgga gggacccagg tggaaatcaa
      421 tcgag
//
LOCUS       KCVT01001233             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22480:3973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001233
VERSION     KCVT01001233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22480:3973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78758.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          121 c          120 g          106 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaccctcttg gatggtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001234             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17950:5367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001234
VERSION     KCVT01001234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17950:5367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78759.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          116 c          122 g          104 t
ORIGIN      
        1 acatggggga ttacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtgggag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001235             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18252:16934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001235
VERSION     KCVT01001235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18252:16934"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78760.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          113 g           92 t
ORIGIN      
        1 acatgggagg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 tcgag
//
LOCUS       KCVT01001236             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19137:9266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001236
VERSION     KCVT01001236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19137:9266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78761.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          114 g          107 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001237             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7157:4246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001237
VERSION     KCVT01001237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7157:4246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78762.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tatcaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagaa ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001238             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19601:13114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001238
VERSION     KCVT01001238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19601:13114"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78763.1"
                     /translation="CQQYDSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          112 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtcg gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa actagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001239             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:12348:12331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001239
VERSION     KCVT01001239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12348:12331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..326
                     /note="immunoglobulin light chain variable region"
     V_region        16..326
     V_segment       16..284
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <266..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78764.1"
                     /translation="CQQYNSEPRTF"
     J_segment       292..326
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>329
                     /gene="IGKC"
BASE COUNT           83 a           85 c           89 g           72 t
ORIGIN      
        1 acatgggggg agtcagaccc agtctccatc ctccctgtct gcatctgtag gagacagagt
       61 caccatcact tgtcgggcga gtcagggcat tcgcagttat ttagcgtggt atcagcagaa
      121 accagggaaa cccccgaagc ccttgatcta ttacgcgtcc actttggaaa gtggggtccc
      181 atcaaggttc agcggcagtg gatctgggac agaattcact ctcaccatca gcagcctgca
      241 gcctgaagat tttgcaactt attactgtca acagtataac agtgagccgc gcactttcgg
      301 tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001240             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7859:18345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001240
VERSION     KCVT01001240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7859:18345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78765.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001241             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20875:13720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001241
VERSION     KCVT01001241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20875:13720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78766.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          123 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atcttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001242             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19618:15811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001242
VERSION     KCVT01001242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19618:15811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78767.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctgggactcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001243             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24052:24270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001243
VERSION     KCVT01001243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24052:24270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78768.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 atgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001244             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20240:19374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001244
VERSION     KCVT01001244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20240:19374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78769.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          121 c          121 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaata cctatttgga atggcaccgg cagatgccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctgacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01001245             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10884:18835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001245
VERSION     KCVT01001245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10884:18835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78770.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001246             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21898:20062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001246
VERSION     KCVT01001246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21898:20062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78771.1"
                     /translation="CQQGYSYPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccct
      121 cctccctgtc cgcatctgta ggagacgcag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcaataa tttaaattgg tttcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 ataagacatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttacccg tggacgttcg gccaaggggc caaggtggag atcaaacgag
//
LOCUS       KCVT01001247             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17554:6527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001247
VERSION     KCVT01001247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17554:6527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78772.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          116 c          107 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 atattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc attagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001248             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19619:9856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001248
VERSION     KCVT01001248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19619:9856"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78773.1"
                     /translation="CQQYDSLPYTF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          109 c          110 g          100 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 cttcctccct gtctgcgtct gtaggagaca cagtcaccat tacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tcttttatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agcggatctg
      301 ggacagaatt cactctcacc atcagtggcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta tgatagttta ccatacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001249             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:25690:14212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001249
VERSION     KCVT01001249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:25690:14212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..348
                     /note="immunoglobulin light chain variable region"
     V_region        27..348
     V_segment       27..310
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78774.1"
                     /translation="CQQYDSDPYSF"
     J_segment       311..348
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           89 a           92 c           91 g           79 t
ORIGIN      
        1 acatggggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca tcctccctgt
       61 ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc attagcagtt
      121 atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc tatttcgcat
      181 ccactttgga aagtggcgtc ccatcaaggt tcagcggcag tggatctggg acagagttca
      241 ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt caacagtatg
      301 acagtgaccc gtacagtttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001250             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9184:5142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001250
VERSION     KCVT01001250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9184:5142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78775.1"
                     /translation="CLQGYNTPVTF"
     J_segment       309..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           81 a           92 c           95 g           79 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcgt ccctgtctgc
       61 atctgtagga gacaaagtca ccatcacttg ccgagccagt cagggtatta gcagttggtt
      121 agcctggtat cagcagagac cagggaaagc ccctaaactc ctgatctata gggcgtccag
      181 tttggcaagt ggggtcccgt caaggttcag cggcagtgga tctgggacgg attacactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat ttttgtctgc agggttacaa
      301 taccccggtc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001251             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13941:20397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001251
VERSION     KCVT01001251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13941:20397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..374
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78776.1"
                     /translation="CQQHDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          117 c          107 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 gtattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctta
      241 tctgtagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatatttct
      361 gtcaacagca tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001252             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14516:20473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001252
VERSION     KCVT01001252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14516:20473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78777.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattgct
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001253             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4945:9840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001253
VERSION     KCVT01001253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4945:9840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78778.1"
                     /translation="CQQGYNTPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          114 c          117 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 ggatattagc agctggttag cctggtatca gctgaagccg gggaaagccc ctaaactctt
      241 gatctataag gcgtccagtt tggcaagagg ggtcccatcg aggttcagcg gcagtggatc
      301 tgggacggat tacactctca ccatcagtag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag ggttacaata ccccgtggac gttcggccaa aggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001254             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19619:19538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001254
VERSION     KCVT01001254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19619:19538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78779.1"
                     /translation="CMQSIKEPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          121 c          110 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagaaccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01001255             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11893:11187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001255
VERSION     KCVT01001255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11893:11187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78780.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca caaaccaggc
      241 cagtctccag agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggc tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg aggtcaaacg ag
//
LOCUS       KCVT01001256             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22100:2536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001256
VERSION     KCVT01001256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22100:2536"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..279
                     /note="immunoglobulin light chain variable region"
     V_region        7..279
     V_segment       7..241
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <219..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78781.1"
                     /translation="CMQALDFPWTF"
     J_segment       242..279
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>282
                     /gene="IGKC"
BASE COUNT           73 a           61 c           82 g           66 t
ORIGIN      
        1 acatgggcag gtctagtcag agcctcttgg atagtgagga tggaaacacc tatttggaat
       61 ggttcctgca gaagccaggc cagtctccac aactcttgat ttatgaggtt tccaaccggg
      121 cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc acactgaaaa
      181 tcagcagagt ggaggctgag gatgttggga tttattactg catgcaagct ctagactttc
      241 cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001257             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20536:12399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001257
VERSION     KCVT01001257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20536:12399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78782.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tctggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01001258             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13224:16083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001258
VERSION     KCVT01001258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13224:16083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78783.1"
                     /translation="CQQGYTTPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          112 g           91 t
ORIGIN      
        1 acatgggagg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattagc agctggttag cctggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatctataag gcgtccagtt tggcaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacggat tacactctca ccatcaacag cctgcagcct gaagatttta caacttatta
      361 ttgtcaacag ggttacacta cccctctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001259             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:6448:19384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001259
VERSION     KCVT01001259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6448:19384"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78784.1"
                     /translation="CMQPLEFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctgtccctgc ccgtcaccct tggagagccg gcctccatct cctgtgggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaacctcta gagtttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001260             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:3225:12743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001260
VERSION     KCVT01001260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:3225:12743"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78785.1"
                     /translation="CQQYDDYPWTF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT           99 a          115 c          113 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag gtgtgacatc cagatgaccc agtctccgtc
      121 ctccctgtct gcatctgtgg gagacaaagt caccatcact tgccatacca gtcagggtat
      181 tagtagtcgg ttagtctggt atcagcagaa accagggaaa gcccctaagc ccctgatgta
      241 tgctgcatcc agtttacaca gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgat gattacccgt ggacgttcgg ccaagggacc aaggtggaaa tcaagcgag
//
LOCUS       KCVT01001261             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:22045:11668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001261
VERSION     KCVT01001261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22045:11668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..439
                     /note="immunoglobulin light chain variable region"
     V_region        99..439
     V_segment       99..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78786.1"
                     /translation="CMQGLEFPPTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          124 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggcga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggtgat ggaaacacct atttggaatg gttcctccag aggccaggcc
      241 agtctccaca cctcttgatt tatggggctt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt tttattactg catgcaaggt ctagagtttc ctccgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001262             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:27500:10677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001262
VERSION     KCVT01001262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:27500:10677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78787.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcgggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001263             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13301:18457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001263
VERSION     KCVT01001263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13301:18457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78788.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01001264             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15586:4078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001264
VERSION     KCVT01001264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15586:4078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78789.1"
                     /translation="CQQHNTYPLTF"
     J_segment       389..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          118 c          104 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 ggacattagt aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatgtattac gcatccaatt tggaaaatgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caagttatta
      361 ctgtcaacag cataatactt acccattgac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01001265             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19960:19951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001265
VERSION     KCVT01001265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19960:19951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78790.1"
                     /translation="CQQYNSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          114 c          107 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcgagtc
      181 agggcattag aagttattta gcgtggtatc agcagaaacc aggaaaagcc ccgaaggcct
      241 tgatctatta cgcatccatt ttagaaagtg cggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagtc tgacgatttt gcaacttatt
      361 actgtcaaca atataacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001266             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17370:7101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001266
VERSION     KCVT01001266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17370:7101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78791.1"
                     /translation="CLQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgct tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001267             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14389:9134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001267
VERSION     KCVT01001267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14389:9134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78792.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg tagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc gacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01001268             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9059:8276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001268
VERSION     KCVT01001268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9059:8276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78793.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga catcgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001269             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15686:12651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001269
VERSION     KCVT01001269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15686:12651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78794.1"
                     /translation="CQQYNSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          114 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagca gttatttagc gtggtatcgg cagaggccag ggaaagcccc ggagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga ctcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001270             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7726:16361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001270
VERSION     KCVT01001270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7726:16361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78795.1"
                     /translation="CLQGDTAPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          114 c          114 g           95 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgtat cggcaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcattaac gattatttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggtgatactg ccccgttcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001271             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12514:7562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001271
VERSION     KCVT01001271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12514:7562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78796.1"
                     /translation="CMQYRHIPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          119 c          114 g          109 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcaactc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagact
      121 ccattctccc tgtccgttag ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttga atagtgaaga cggaaacacc tatttggatt ggtacctgca gaggccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01001272             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:2905:9025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001272
VERSION     KCVT01001272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:2905:9025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78797.1"
                     /translation="CQQYSTLPLTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          107 a          108 c          111 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcaacctga ggattttgca agttattact
      361 gtcaacagta tagtacttta ccgttgacgt tcggccaagg gaccaaggtg gaaatcaaag
      421 gag
//
LOCUS       KCVT01001273             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13662:20077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001273
VERSION     KCVT01001273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13662:20077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78798.1"
                     /translation="CQQHNTYPLTF"
     J_segment       387..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          119 c          103 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 acattagtaa tgatttagcc tggtatcagc agaaaccagg gacagccccg aagcccctga
      241 tgtattacgc atccaatttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca agttattact
      361 gtcaacagca taatacttac ccattgactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001274             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6733:12651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001274
VERSION     KCVT01001274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6733:12651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78799.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactggaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001275             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:9940:21427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001275
VERSION     KCVT01001275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9940:21427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78800.1"
                     /translation="CMQGKEFPYSF"
     J_segment       404..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          117 c          125 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaagctc cttgctcagc
       61 tcctggggct gctaatgctc tggctccctg gatccagtgg ggatgttgtg atgacccaga
      121 ctccactctc cctgccagtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaggccag
      241 gccagtctcc acagcccttg atttatgggg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag gcaaagagtt tccgtacagt tttggccagg
      421 ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01001276             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8927:15714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001276
VERSION     KCVT01001276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8927:15714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..422
                     /note="immunoglobulin light chain variable region"
     V_region        95..422
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78801.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       384..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           99 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacact cagttgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcggacaa gtcaggacat
      181 tagcagttat ttagcctggt atcagcagaa accagggaaa gcccctaacc tcctgatcta
      241 taaggcgtcc agtttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca ggctgaagat tttgcagttt attactgtca
      361 acagcgtatt ggttacccgt acatgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001277             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:28805:13788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001277
VERSION     KCVT01001277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:28805:13788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78802.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           97 a          116 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagcttg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct gggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggc acctgcagag gccaggccag
      241 tctccacagt tcttgattta tgaagtttcc tatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagttccctt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001278             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5251:7166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001278
VERSION     KCVT01001278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5251:7166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..393
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78803.1"
                     /translation="CLQTKNSPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          103 a          117 c          114 g          100 t
ORIGIN      
        1 acatggggag gagcagcctc tagttcagct ctcagaaatg gggtcctggg ctcctttcct
       61 gtggatcctc ctgctctgtg ctccaggctg caatggggac attgtgctga cccagtctcc
      121 agcctctttg gccgtgtctc cagggcagag ggccaccatc acctgcagag ccagtgagag
      181 tgtcagtgtc tttggaataa acctcattca ctggtatcag cagaaaccag gacaacctcc
      241 taaatccctg atttaccaag catccaataa agacactggg gtcccagcca ggttcagcgg
      301 cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaagctg acgatgctgc
      361 agattattac tgtctgcaga ctaagaattc tccgtggacg tttggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01001279             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18474:10461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001279
VERSION     KCVT01001279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18474:10461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78804.1"
                     /translation="CSQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           87 a          122 c          123 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gtccgtcacc cctggagacc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcctaca taggaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgctcg caagatatac agcttccgct cactttcggt ggagggacca
      421 gggtggagat caaacgag
//
LOCUS       KCVT01001280             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12525:11355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001280
VERSION     KCVT01001280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12525:11355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78805.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          112 c          109 g           98 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001281             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16796:7579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001281
VERSION     KCVT01001281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16796:7579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78806.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tactaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagag ttcgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001282             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14880:5482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001282
VERSION     KCVT01001282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14880:5482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..423
                     /note="immunoglobulin light chain variable region"
     V_region        84..423
     V_segment       84..385
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78807.1"
                     /translation="CMQALEFPLTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           92 a          112 c          119 g          103 t
ORIGIN      
        1 acatgggggg tcaccttctc acaatgaggc tccctgctca gctcctggga ctgctcatgc
       61 tctggctccc tgtatccagt ggggacattg tgatgaccca gactccactc tccctgcccg
      121 tcacccttgg agagccggcc tccatgtcct gcaggtctag tcagagtctc ttggatagtg
      181 aggatggaaa cacctatttg gaatggtacc tgcagaagcc aggccagtct ccacagctct
      241 tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt ggcggtgggt
      301 cagacactga tttcacactg aaaatcagca gagtggaggc tgatgatgtt ggggtttatt
      361 actgcatgca agctctagag tttccgttga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001283             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23845:7457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001283
VERSION     KCVT01001283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23845:7457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78808.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacatagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagctgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acagtataac agtgacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001284             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16500:18179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001284
VERSION     KCVT01001284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16500:18179"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78809.1"
                     /translation="CHQHNSFPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          114 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagaa acagtcaccg tcacttgtcg ggcaagtcgg
      181 ggcgttagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaggcccctg
      241 atctattatg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac aatcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaccaac ataatagttt cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001285             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12132:11853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001285
VERSION     KCVT01001285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12132:11853"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78810.1"
                     /translation="CQQYNTLPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          117 c          103 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga gattcagatg acccagtctc
      121 catcctccct gtctgcctct gtcggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcaa ttatttaaat tggtatcagc agagaccggg gaaagcccct aaactcctga
      241 tctattatgc atcccgtttg gagaatgggg tcccatcaaa gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagtagcc tgcaacctga agattttgca gcttattact
      361 gtcagcagta taatacctta ccattcactt tcggccccgg gaccaaactg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001286             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9440:23299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001286
VERSION     KCVT01001286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9440:23299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78811.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctcaggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001287             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15102:7311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001287
VERSION     KCVT01001287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15102:7311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78812.1"
                     /translation="CLQYKSFPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          111 a          117 c           95 g           97 t
ORIGIN      
        1 acatggggca gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccatcac ttgccggaca agtcaaggta
      181 ttaccaatta tttacattgg tttcaacaga aaccagggaa agcccctaaa ctcctgatct
      241 atgaaacatc cagtttgaca agtggggtcc catcaaggtt cagcggcagc gcatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtataa aagtttcccg tacacttttg gccaggggac caaactggag atcaaacgag
//
LOCUS       KCVT01001288             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14486:13596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001288
VERSION     KCVT01001288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14486:13596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78813.1"
                     /translation="CMQGLEFPPTF"
     J_segment       409..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          124 c          120 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtggcg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtggtga tggaaacacc tatttggaat ggttcctcca gaggccaggc
      241 cagtctccac acctcttgat ttatggggct tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc ctccgacatt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001289             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20211:17943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001289
VERSION     KCVT01001289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20211:17943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78814.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc accaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgactcgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01001290             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8936:16557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001290
VERSION     KCVT01001290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8936:16557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78815.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          116 c          117 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcaacag aaaccaggac aacctcctaa
      241 actcctgatt taccaagcaa tcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaacctgacg atggtgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 gatcaaacga g
//
LOCUS       KCVT01001291             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5239:8301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001291
VERSION     KCVT01001291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5239:8301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..433
                     /note="immunoglobulin light chain variable region"
     V_region        98..433
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78816.1"
                     /translation="CMQALEFPRTF"
     J_segment       402..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>440
                     /gene="IGKC"
BASE COUNT           94 a          124 c          116 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgtatc cagtggtgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgcggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt ggctcagaca ctgatttcac actgaaaatc agcagagtgg aggctgaaga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct cggacgttcg gccaggggac
      421 caaggtggaa atcgaacgag
//
LOCUS       KCVT01001292             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:8738:13304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001292
VERSION     KCVT01001292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:8738:13304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78817.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          121 c          115 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cattggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg ttcctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001293             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22670:14212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001293
VERSION     KCVT01001293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22670:14212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78818.1"
                     /translation="CQQVYTNPAF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          102 a          112 c          105 g           98 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccaggtgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataggaa tttagcgtgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 atgctgcatc cagattgcaa agtgggtttc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcaacctac agcctgaaga ttctgcaatt tattactgtc
      361 aacaggttta tactaacccg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01001294             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21449:12224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001294
VERSION     KCVT01001294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21449:12224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78819.1"
                     /translation="CQQVYSYPCSF"
     J_segment       388..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          108 c          111 g          105 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ctgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gatatccaga tgacccagtc
      121 tccatctgcc ttgtctgcat ctgtaggaga cagagtcacc atctcttgcc gggcaagtca
      181 gaacatttat gataatttag cgtggtttca gcagaaagca gggaaagccc ctaaactcct
      241 gatctatact gcatccagat tgcaaagtgg gattccctct cggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag tctgcagcct gaagattctg cagtttatta
      361 ctgtcaacag gtttatagtt acccgtgcag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001295             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25336:11957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001295
VERSION     KCVT01001295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25336:11957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78820.1"
                     /translation="CMQALEFPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           98 a          124 c          114 g          101 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagtct
      181 ctgggatagt gaggaaggaa acacctattt ggagtggtac ctacagaggc caggccagtc
      241 tccacagctc ttaattcatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcacc agagtggagg ctgaggatgt
      361 tgggacttat tactgcatgc aagctctaga gtttccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01001296             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15600:7008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001296
VERSION     KCVT01001296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15600:7008"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78821.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatgggggg tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gagactgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001297             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19712:12364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001297
VERSION     KCVT01001297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19712:12364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78822.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccattttg gaaagtgggg tcccatcaag gttcagcgcc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001298             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23181:6317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001298
VERSION     KCVT01001298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23181:6317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..319
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78823.1"
                     /translation="CQQYNGYPPTF"
     J_segment       332..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           92 a          101 c           94 g           82 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc
       61 agtctccatc ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa
      121 gtcagggcat taccaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc
      181 ccctgatcta ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      301 attattgtca acagtataat ggataccctc cgacgttcgg ccaagggacc agggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01001299             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18480:13983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001299
VERSION     KCVT01001299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18480:13983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78824.1"
                     /translation="CQHYISSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           94 a          132 c          109 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tcgccaggcc cccgggctcc
      241 tcatctatgg tgcgtccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagattct gcagtgtatt
      361 actgtcagca ctatattagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01001300             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19573:20238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001300
VERSION     KCVT01001300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19573:20238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78825.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          118 c          119 g          107 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagat
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ttatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc attgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001301             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25435:16534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001301
VERSION     KCVT01001301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25435:16534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..333
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78826.1"
                     /translation="CLQGDTAPFTF"
     J_segment       350..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           89 a          106 c          103 g           90 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctgggg ctccttctgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgaccca gtctccatct tccctgtctg catcggcagg agacagagtc
      121 accatcactt gccgggcaag tcagggcatt aacgattatt taagttggta tcagcagaaa
      181 ccaggaaaac ctcctaagcg cctgatttat gctgcatcca gtttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcagctta ttactgtcta cagggtgata ctgccccgtt cactttcggc
      361 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01001302             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17641:2566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001302
VERSION     KCVT01001302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17641:2566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..375
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78827.1"
                     /translation="CQQYNSLPYTF"
     J_segment       376..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          111 a          109 c           97 g           99 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctggga
       61 ctcctgctgc tctggctccc aggtgccatg tgacattcag atgacccagt ctccatcctc
      121 cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc aggacattag
      181 tatttattta aattggtatc aacaaaaacc ggggaaagcc cctaagctcc tgatctatta
      241 tggaaaccgt ttggaaagtg gggtcccatc aagtttcagc ggcagtggat ctgggacaga
      301 attcactctc accatcaaca gcctgcaacc tgaagatttt gcaacttatt actgtcaaca
      361 gtataatagt ttaccgtaca cttttggcca cgggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01001303             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6825:12463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001303
VERSION     KCVT01001303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6825:12463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..265
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78828.1"
                     /translation="CMQALEFPLTF"
     J_segment       266..302
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           72 a           69 c           91 g           73 t
ORIGIN      
        1 acatggggga gagccggcct ccatctcctg caggtctagt cagagcctct tggatagtga
       61 ggatggaaac acctatttgg aatggtacct gcacaagcca ggccagtctc cagagctctt
      121 gatttatgag gtttccaagc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      181 agacactgat ttcacactga aaatcagcag attggaggct gaggatgttg ggctttatta
      241 ctgtatgcaa gctctagagt ttcctctcac tttcggcgga gggaccaagg tggaggtcaa
      301 acgag
//
LOCUS       KCVT01001304             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20205:9972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001304
VERSION     KCVT01001304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20205:9972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78829.1"
                     /translation="CLQGYTSPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          113 c          110 g           95 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcgtcggtag gagacagagt caccatcgct tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc gcctgatcta
      241 tgctgcatcc agtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggttat acttccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001305             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:28628:8706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001305
VERSION     KCVT01001305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:28628:8706"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78830.1"
                     /translation="CIQGLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgacgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atacaaggtc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001306             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15082:17456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001306
VERSION     KCVT01001306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15082:17456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78831.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          113 c          102 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001307             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:25775:12585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001307
VERSION     KCVT01001307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25775:12585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78832.1"
                     /translation="CQKYSSFPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          123 c          109 g           94 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaacaccgg acaagttata ttgactcagt
      121 ctccagccac tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccagactcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagaa gtatagtagt ttcccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01001308             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19068:7766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001308
VERSION     KCVT01001308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19068:7766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78833.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          110 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca tcacaaacct gggcaggctc ccaagctcct
      241 cctctttggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001309             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18860:18257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001309
VERSION     KCVT01001309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18860:18257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78834.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          105 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccggg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01001310             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17016:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001310
VERSION     KCVT01001310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17016:10474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..367
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78835.1"
                     /translation="CQQGQSYPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          118 c          108 g           93 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccctgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttatattggt atcaactgaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc agtttgcaag gtgggagtcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcag agttacccgc tcactttcgg cggagggacc aaggtagaaa tcaaacgag
//
LOCUS       KCVT01001311             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12764:18813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001311
VERSION     KCVT01001311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12764:18813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..397
                     /note="immunoglobulin light chain variable region"
     V_region        95..397
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78836.1"
                     /translation="CQQGHGLPFTF"
     J_segment       379..397
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           89 a          105 c          105 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccgtc
      121 ctccctgtct gcttctgtag gagacagagt caccatcagt tgccgggcaa gtcaggacat
      181 tagcagttat ttatattggt atcagcagaa accggggaga gcccctaagc ttctgattta
      241 taaggcatat cttttggaag atggggtccc atcaaggttc agcggcagtg gatctggggc
      301 agagttcact ctcactatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagggtcat ggtttaccat tcactttcgg ccccggg
//
LOCUS       KCVT01001312             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20320:10937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001312
VERSION     KCVT01001312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20320:10937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78837.1"
                     /translation="CQQVYSSPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          113 c          106 g          103 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtgg gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagttat ttagcgtggt atcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgtatcc agattgcaaa gtggggttcc ctctcggttc agcggcagtg gaactgggac
      301 agatttcact ctcagcatca gcagcctaca gcctgaagat tctgccggtt attactgtca
      361 acaggtttat agtagtccat tcactttcgg ccccgggacc aaactggcta tcaaacgag
//
LOCUS       KCVT01001313             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10655:7215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001313
VERSION     KCVT01001313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10655:7215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    172..314
                     /note="immunoglobulin light chain variable region"
     V_region        172..314
     V_segment       172..277
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78838.1"
                     /translation="CLQYKTFPFTF"
     J_segment       285..314
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>318
                     /gene="IGKC"
BASE COUNT           74 a           94 c           79 g           71 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccgtc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggttc
      181 agcggcagtg catctgggac agaattcact ctcccatcag cggcctgcag cctgaagatt
      241 ttgcaactta tcactgtcta cagtataaaa ctttcccgtt cacctttggc caggggacca
      301 aactggagat caaaggag
//
LOCUS       KCVT01001314             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18863:4774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001314
VERSION     KCVT01001314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18863:4774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..391
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78839.1"
                     /translation="CLQGYTPPYTF"
     J_segment       406..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          123 c          113 g          101 t
ORIGIN      
        1 acatggggac gctggtcaca cttcatgtag gagtcagaac cactcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct ccttctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacccagt ctccatcttc cctgtctgca tcggtaggag acagagtcac
      181 catcacttgc cgggcaagtc agggcattag cgattattta agttggtatc agcagaaacc
      241 aggaaaacct cctaagcgcc tgatctatgc tgcatccagt ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgaaacaga gttcactctc accatcacca gcctgcagcc
      361 tgaagatttt gcagcttatt actgtctaca gggttatact cccccgtaca cttttggcca
      421 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01001315             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6423:3544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001315
VERSION     KCVT01001315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6423:3544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78840.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>423
                     /gene="IGKC"
BASE COUNT          104 a          109 c          111 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcgaac
      421 gag
//
LOCUS       KCVT01001316             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13773:15862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001316
VERSION     KCVT01001316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13773:15862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..372
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78841.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       380..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>415
                     /gene="IGKC"
BASE COUNT          108 a          104 c          101 g          102 t
ORIGIN      
        1 acatggggag aaccactcag gacacaggat ggacatgacg gtccccgctt atctcctggg
       61 gctccttctg ctctggctcc cagatgtgac atccagatga cccagtctcc atcttccctg
      121 tctgcatctg taggagacaa agtcaccatc acttgcaggg caagtcagga cattggtaat
      181 tatttaaatt ggtatcagca gaaaccagga aaagctccta aggtcctgat ctatggtgta
      241 tccaatttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatctt
      301 actctcacca tcagcagcct gcagcctgaa gattttgcaa cgtattattg tcaaacgttt
      361 aaaagttacc tttcggtccc tttcggcgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01001317             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19483:2366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001317
VERSION     KCVT01001317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19483:2366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..264
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78842.1"
                     /translation="CQQYDSDSLTF"
     J_segment       269..306
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           79 a           76 c           82 g           72 t
ORIGIN      
        1 acatgggatc ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga
       61 ctcaggacat tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc
      121 ccttgatcta ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg
      181 gatctgggac agaattcact ctcaccatca gcagcctgca ggctgaagat tttgcaactt
      241 attactgtca acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga
      301 tcaaacgag
//
LOCUS       KCVT01001318             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14494:13348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001318
VERSION     KCVT01001318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14494:13348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78843.1"
                     /translation="CQQHYGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcattatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001319             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19755:16061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001319
VERSION     KCVT01001319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19755:16061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78844.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgtgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001320             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:8139:6662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001320
VERSION     KCVT01001320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8139:6662"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78845.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggtt ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001321             377 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14679:12751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001321
VERSION     KCVT01001321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 377)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14679:12751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    53..374
                     /note="immunoglobulin light chain variable region"
     V_region        53..374
     V_segment       53..331
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <314..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78846.1"
                     /translation="CQQGYGFPFTF"
     J_segment       337..374
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        375..>377
                     /gene="IGKC"
BASE COUNT           88 a          106 c           89 g           94 t
ORIGIN      
        1 acatgggcag ctccttgggc tcctgctgct ctggctccca ggtgccagat gtgacatcca
       61 gatgacgcag tctccatcct ccctgtccgc atctgtagga gacacagtcg cgatcacttg
      121 cctggcgagt caaggcattg gcaataattt aaattggtat cagcagaaac cagggaaagc
      181 ccctaaactc ctgatctata cggcatccaa tttacatggt gggattccct ctcggttcag
      241 cggcagtgga tctgggacgg atttcactct caccatcaac agcctgcagc ctgaagattt
      301 tgccacttat tactgtcaac agggttatgg ttttccattc actttcggcc ccgggaccaa
      361 actggatatc aaacgag
//
LOCUS       KCVT01001322             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:9155:6483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001322
VERSION     KCVT01001322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9155:6483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..431
                     /note="immunoglobulin light chain variable region"
     V_region        99..431
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78847.1"
                     /translation="CMQPLEFPLTF"
     J_segment       404..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgctttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gttgacgttc ggccaaggga
      421 ccagggtgga acccaaacga g
//
LOCUS       KCVT01001323             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24288:5394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001323
VERSION     KCVT01001323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24288:5394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78848.1"
                     /translation="CQQYDSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagccaggac acagcttgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattag cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctattt cgcatccgtt ttggaaagtg gcgtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001324             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14406:11138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001324
VERSION     KCVT01001324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14406:11138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78849.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001325             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25082:8466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001325
VERSION     KCVT01001325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25082:8466"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78850.1"
                     /translation="CQQYNSEPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          112 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga gccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001326             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7626:20872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001326
VERSION     KCVT01001326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7626:20872"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78851.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          111 g           90 t
ORIGIN      
        1 acatggggag acccggtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagg cattgatcta
      241 ttacgcgtcc actttggaaa atggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001327             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14370:14400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001327
VERSION     KCVT01001327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14370:14400"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..361
                     /note="immunoglobulin light chain variable region"
     V_region        84..361
     V_segment       84..319
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <301..>333
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78852.1"
                     /translation="CQQYDSDSLTF"
     J_segment       324..361
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        362..>364
                     /gene="IGKC"
BASE COUNT           91 a           97 c           97 g           79 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggagac agagtcacca tcacttgtcg ggcgactcag
      121 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      181 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      241 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      301 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      361 cgag
//
LOCUS       KCVT01001328             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15209:12079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001328
VERSION     KCVT01001328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15209:12079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78853.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          117 c          125 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatgtggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctggg
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001329             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9345:15918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001329
VERSION     KCVT01001329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9345:15918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78854.1"
                     /translation="CMQGLDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaaggtc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001330             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19731:9579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001330
VERSION     KCVT01001330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19731:9579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78855.1"
                     /translation="CQQHNGYPPTF"
     J_segment       367..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          102 a          112 c          101 g           89 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tataggagac acagtcacca tcacttgtcg ggcaagtcag ggcattacga atgatttagc
      181 ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg atctattacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattat tgtcaacagc ataatggata
      361 tcctccgacg ttcggccaag ggaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01001331             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8303:13135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001331
VERSION     KCVT01001331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8303:13135"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78856.1"
                     /translation="CLQGDSTPFTF"
     J_segment       389..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          101 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccggg aaaagctcct aggcgcctaa
      241 tctatgctgc atccactttg gaaagtgggg tcccaccaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg tgatagtacc ccgttcactt ttggccaggg gaccaaagtg gacgtcaaac
      421 gag
//
LOCUS       KCVT01001332             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11708:16847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001332
VERSION     KCVT01001332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11708:16847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..396
                     /note="immunoglobulin light chain variable region"
     V_region        75..396
     V_segment       75..354
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <336..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78857.1"
                     /translation="CQHSYSIPYSF"
     J_segment       359..396
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>399
                     /gene="IGKC"
BASE COUNT           99 a          104 c           97 g           99 t
ORIGIN      
        1 acatgggcat ggacatgagg gcctctgctc agctcctagg gctcctgctg ctctggctcc
       61 caggcgccag atgtgacatc cagatgaccc agtctccatc ctccctgtct gcatctgtag
      121 gagacagagt caccatcact tgcagggcaa gtgagaacgt taacattttt ttacattggt
      181 atcagcagaa accaggtaaa gcccctaagc tcctgatcta tgctgcatcc aaattgcaaa
      241 gtggggtccc atcgaggttc accggcagtg gatctgggac tgatttcact ctcaccatca
      301 atagtctgca gcctgaagat gttgcaactt attactgtca gcatagttat agtattccgt
      361 acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001333             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16556:7135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001333
VERSION     KCVT01001333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16556:7135"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78858.1"
                     /translation="CMQALEFPRTF"
     J_segment       406..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          121 c          122 g          102 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactttt cctggccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggctagtgag gatggaaaca cttatttgga ctggtaccta cagaggccag
      241 gccagactcc ccagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 gggtcagagg cagtgggtca gacactgagt tcacactgaa aatcagcaga gtggaggctg
      361 aggatcttgg gatttattac tgcatgcaag ctctagagtt tcctcggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01001334             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:7731:16163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001334
VERSION     KCVT01001334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7731:16163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..301
                     /note="immunoglobulin light chain variable region"
     V_region        7..301
     V_segment       7..263
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <241..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78859.1"
                     /translation="CMQALEFPLTF"
     J_segment       264..301
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>304
                     /gene="IGKC"
BASE COUNT           74 a           70 c           89 g           71 t
ORIGIN      
        1 acatggggag agccggcctc catctcctgc aggtctagtc agagcctctt ggatagtgag
       61 gatggaaaca cctatttgga atggtacctg cagaagccag gccagtctcc acagctcttg
      121 atttatgaga tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca
      181 gacactgatt tcacactgaa aatcagcaca gtggaggctg aggatgttgg ggtttattac
      241 tgcatgcaag ctctagagtt tccgctcact ttcggtggag ggaccaaggt ggagatcaaa
      301 cgag
//
LOCUS       KCVT01001335             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22433:3906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001335
VERSION     KCVT01001335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22433:3906"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78860.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001336             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:22524:8799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001336
VERSION     KCVT01001336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22524:8799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78861.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggttccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gttcacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttgga
      361 atttattgct gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01001337             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12381:11077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001337
VERSION     KCVT01001337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12381:11077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78862.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          119 c          115 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccaac agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaagatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001338             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10519:12870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001338
VERSION     KCVT01001338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10519:12870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..363
                     /note="immunoglobulin light chain variable region"
     V_region        86..363
     V_segment       86..321
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78863.1"
                     /translation="CQQYDSDSLTF"
     J_segment       326..363
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT           92 a           97 c           98 g           79 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggag acagagtcac catcacttgt cgggcgactc
      121 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      181 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      241 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      301 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      361 aacgag
//
LOCUS       KCVT01001339             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14662:18947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001339
VERSION     KCVT01001339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14662:18947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..441
                     /note="immunoglobulin light chain variable region"
     V_region        120..441
     V_segment       120..389
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78864.1"
                     /translation="CLQGDTAPFTF"
     J_segment       406..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          106 a          120 c          118 g          100 t
ORIGIN      
        1 acatgggggc tggtcacact tcatgtagga gtcagaacca ctcaggacac agcatggaca
       61 tgagggtccc cgctcagctc ctggggctcc ttctgctctg gctcccaggt gccagatgtg
      121 acatccagat gacccagtct ccatcttccc tgtctgcatc ggcaggagac agagtcacca
      181 tcacttgccg ggcaagtcag ggcattaacg attatttaag ttggtatcag cagaaaccag
      241 gaaaacctcc taagcgcctg atttatgctg catccagttt ggaaagtggg gtcccatcaa
      301 ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc ctgcagcctg
      361 aagattttgc agcttattac tgtctacagg gtgatactgc cccgttcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001340             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12841:18433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001340
VERSION     KCVT01001340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12841:18433"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78865.1"
                     /translation="CQQYHSLPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          110 c          108 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctct tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggtattagta gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taacctcctg
      241 atctattata caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctacagcctg aagattttgc aaattatttc
      361 tgtcaacagt atcatagtct accgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001341             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18050:16588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001341
VERSION     KCVT01001341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18050:16588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..439
                     /note="immunoglobulin light chain variable region"
     V_region        104..439
     V_segment       104..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78866.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          118 c          123 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg actttgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001342             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:24791:7105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001342
VERSION     KCVT01001342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24791:7105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78867.1"
                     /translation="CQQYDSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          118 c          113 g           90 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggcgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001343             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24615:5600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001343
VERSION     KCVT01001343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24615:5600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78868.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001344             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9369:12638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001344
VERSION     KCVT01001344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9369:12638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..403
                     /note="immunoglobulin light chain variable region"
     V_region        112..403
     V_segment       112..365
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78869.1"
                     /translation="CMQALDFPLTF"
     J_segment       366..403
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT           90 a          101 c          116 g           99 t
ORIGIN      
        1 acatgggggg gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gatattgtga tgacccggcc
      121 tccatctcct gtaggtctag tcagagtctc ttggctagtg aggatggaaa cacctatttg
      181 gaatggtacc tgcagaagcc aggccagtct ccacaactct tgatttatga agtttccaag
      241 cgggcctctg gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg
      301 aagatcagca gagtggaggc tgaggatgtt ggggtttatt actgcatgca agctctagac
      361 tttccgctca ctttcggcgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001345             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:25588:21647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001345
VERSION     KCVT01001345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25588:21647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78870.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc cctgacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001346             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19333:16609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001346
VERSION     KCVT01001346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19333:16609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78871.1"
                     /translation="CLQYKSFPYTF"
     J_segment       385..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          108 a          116 c           97 g           97 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtggg agacactgtc accatcactt gccggacaag tcaaggtatt
      181 accaattatt tacattggtt tcagcagaaa ccagggagag cccctaagct cctgatctat
      241 gaaacatcca gtttgacaag tggggtccca tcaaggttca gcggcagtgc atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa gtttcccgta cacctttggc caggggacca aactggagat caaacgag
//
LOCUS       KCVT01001347             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16385:15322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001347
VERSION     KCVT01001347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16385:15322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78872.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001348             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21938:15720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001348
VERSION     KCVT01001348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21938:15720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..278
                     /note="immunoglobulin light chain variable region"
     V_region        10..278
     V_segment       10..240
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78873.1"
                     /translation="CQQYDSDPFTF"
     J_segment       243..278
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>281
                     /gene="IGKC"
BASE COUNT           73 a           68 c           77 g           63 t
ORIGIN      
        1 acatgggaga gtcaccatca cttgtcgggc gagtcagggc attcgcagtt atttagcgtg
       61 gtatcagcag aaaccaggga aagccccgaa gcccttgatc tattacgcgt ccagtttgga
      121 aagtggggtc ccatcaaggt tcagcggcgg tggatctggg acagaattca ctctcaccat
      181 cagcagcctg cagcctgaag attttgcaac ttattactgt caacagtatg acagtgaccc
      241 gttcactttc ggtggaggga ccaaggtaga catcaaacga g
//
LOCUS       KCVT01001349             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16492:13583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001349
VERSION     KCVT01001349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16492:13583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78874.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g           94 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcagcaga acccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01001350             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9734:15607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001350
VERSION     KCVT01001350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9734:15607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..287
                     /note="immunoglobulin light chain variable region"
     V_region        13..287
     V_segment       13..245
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78875.1"
                     /translation="CQQYDSDSLTF"
     J_segment       250..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           75 a           72 c           77 g           66 t
ORIGIN      
        1 acatggggag tcagacccag tctccatcac ttgtcgggcg actcaggaca ttcgcagtta
       61 tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc
      121 cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtatga
      241 cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001351             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20760:13076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001351
VERSION     KCVT01001351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20760:13076"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78876.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcgggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001352             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21295:14993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001352
VERSION     KCVT01001352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21295:14993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78877.1"
                     /translation="CLHYNSDPWTF"
     J_segment       406..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          115 a          111 c          112 g          108 t
ORIGIN      
        1 acatggggag gttggttaca cttcatgtag aagttagaac cactcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct ccttctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacccagt ctccatcttc cctgtctgca tctgtaagag acagagtcac
      181 cttcacttgc agggcaagtc agggcattac aacttattta aattggtgtc agcagaaatc
      241 aggaaaaact cctaagcgcc tgatctgtgt tgaaaacagt ttggaaagtg gggtcccatc
      301 aaggttcagt ggcagtggat ctgggacagg tttcactctc accatcagca gcctgcagcc
      361 tgaagatttt acaccttatt actgtcttca ttataacagt gacccgtgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001353             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16887:11767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001353
VERSION     KCVT01001353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16887:11767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78878.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctaatcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggcacctgca gaagccaggc
      241 cagtctctac aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatttctg catgcaggct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001354             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15946:9969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001354
VERSION     KCVT01001354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15946:9969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78879.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           94 a          122 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct ttttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcacacga g
//
LOCUS       KCVT01001355             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24445:13830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001355
VERSION     KCVT01001355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24445:13830"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78880.1"
                     /translation="CQQYNRLPRTF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>420
                     /gene="IGKC"
BASE COUNT          104 a          112 c          110 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttagtcaata tttaaattgg tatcagcaga aaccggggaa agcccctagg ctcctcatct
      241 attatgtaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tattactgtc
      361 agcagtataa tcgtttacct cggacgttcg gccaagggac caaggtggaa atcagacgag
//
LOCUS       KCVT01001356             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9995:9833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001356
VERSION     KCVT01001356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9995:9833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78881.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          112 a          118 c          104 g           88 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcacga
      181 tattaacaac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aggtcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggttctgg
      301 gacagatttc actctcacca tcaacaacct gcagcctgaa gatatcgcaa catattactg
      361 tcaacaacat gatgattccc ctcggacctt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001357             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9061:14575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001357
VERSION     KCVT01001357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9061:14575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78882.1"
                     /translation="CQQYNSEPRTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           90 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa acccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgagccg cgcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001358             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15178:10691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001358
VERSION     KCVT01001358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15178:10691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78883.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggactaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001359             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17293:3521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001359
VERSION     KCVT01001359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17293:3521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78884.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc cgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001360             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:22809:15780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001360
VERSION     KCVT01001360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22809:15780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78885.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          106 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgtatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagtctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001361             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23153:2944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001361
VERSION     KCVT01001361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23153:2944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78886.1"
                     /translation="CQQGYGFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          102 g          102 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cgcgatcact tgcctggtga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tacggcatcc aatttacatg gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca acagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat ggttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01001362             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16727:9668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001362
VERSION     KCVT01001362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16727:9668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78887.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tacatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001363             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15172:7371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001363
VERSION     KCVT01001363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15172:7371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78888.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gaggctgagg
      361 atgttgggct ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga ggtcaaacga g
//
LOCUS       KCVT01001364             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6026:16332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001364
VERSION     KCVT01001364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6026:16332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78889.1"
                     /translation="CQQNSNWSLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggtctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001365             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10123:10487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001365
VERSION     KCVT01001365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10123:10487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78890.1"
                     /translation="CMQYKHIPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagct ggatacacct atttggattg gtacctgcag aagccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtgacag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaataca aacacattcc atggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001366             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10936:5964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001366
VERSION     KCVT01001366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10936:5964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..432
                     /note="immunoglobulin light chain variable region"
     V_region        124..432
     V_segment       124..395
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78891.1"
                     /translation="CQQNSNWPLTF"
     J_segment       396..432
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT          101 a          125 c          122 g           87 t
ORIGIN      
        1 acatggggat gcctgggtca gagctctggg gaggaactgc tcagttagga cccagaggga
       61 accatggaag ccccagcaca gcttctcttc ttcctgctgc tctggctccc agataccacc
      121 ggagaaatag tgctgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc
      181 accctctcct gcagggccag tcagagtgtc agcagcagca gcagaaacct gggcaggctc
      241 ccagactcct catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg
      301 gcagtgggtc tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg
      361 cactttatta ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg
      421 tggagatcaa acgag
//
LOCUS       KCVT01001367             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16377:4750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001367
VERSION     KCVT01001367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16377:4750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78892.1"
                     /translation="CQQYNSDPRTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           90 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgacccg cgcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001368             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7206:8747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001368
VERSION     KCVT01001368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7206:8747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78893.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tacatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001369             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14188:5193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001369
VERSION     KCVT01001369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14188:5193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78894.1"
                     /translation="CQKYISSPFTF"
     J_segment       381..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           96 a          130 c          104 g           91 t
ORIGIN      
        1 acatgggggc tgctcagtta ggacccagag agaaccatgg aaatcccagc tcagcttctc
       61 ttcctcctgc tactgtggct cccaggtacc accggacaac ttatattgac tcagtctcca
      121 gccaccctgt ctctgtctcc aggggaaaga gccaccctct cctgcagggc cagtcagagt
      181 gttggcagca gcttagcctg gtaccagcag aaacctgggc aggcccccag gctcctcctc
      241 tatggtgcat ccagcagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag attttgcagt atattactgt
      361 cagaaatata ttagctcccc attcactttc ggccccggga ccaaactgga tatcaaacga
      421 g
//
LOCUS       KCVT01001370             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8331:10430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001370
VERSION     KCVT01001370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8331:10430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78895.1"
                     /translation="CQQHDNMPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          113 c          113 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgcagggcca gtcagggtat
      181 tagcaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tagggcatgg aatttggaaa caggggtccc atcaaggttc agtggaagtg gatccgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat aatatgccgc tcactttcgg tggagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01001371             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17378:4964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001371
VERSION     KCVT01001371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17378:4964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78896.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          117 c          108 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agattcacca tcacttgtcg gacgagtcag
      181 ggcattcgca attatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctatttcg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctacagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001372             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11470:11522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001372
VERSION     KCVT01001372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11470:11522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..365
                     /note="immunoglobulin light chain variable region"
     V_region        86..365
     V_segment       86..328
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78897.1"
                     /translation="CQQDYHWPPTF"
     J_segment       331..365
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           90 a          105 c           99 g           74 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccagg ggaaagagcc accctctcct gcagggccag
      121 tcagagtgtt ggcagcacct taacctggta ccaccagaag cctgggcagg ctcccaagct
      181 cctcatctat ggtccatcca tcagggccag cggcatccca gacagtttca gtggcagtgg
      241 gtctggaaca gaatttactc tcaccatcag cagcctggag actgaagatg ttggagttta
      301 ttactgtcag caggattatc actggcctcc gacgttcggc caagggacca aggtggaaat
      361 caaacgag
//
LOCUS       KCVT01001373             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17948:16746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001373
VERSION     KCVT01001373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17948:16746"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..391
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78898.1"
                     /translation="CLQESNWSYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           99 a          122 c          125 g           88 t
ORIGIN      
        1 acatgggggc tctggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc
       61 agcacagctt ctcttcctcc tgctgctctg gctcccagat agtaccggag aaatagtggt
      121 gacacagtct ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag
      181 ggccagtcag agtgtcaaaa gcaggttagc ctggtaccag cagaaacctg ggcaagctcc
      241 caggctcctc atgtatgatg cgtccagcag ggccactggc atcccagaca ggttcactgg
      301 cagcgggtct gggccagagt tcactctcac catcagcagc ctggagcctg aagatgttgc
      361 ggtttatttc tgtcttcagg agagtaactg gtcgtacagc tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01001374             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:27097:9819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001374
VERSION     KCVT01001374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:27097:9819"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78899.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          114 c          111 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac ttttggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001375             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15497:7457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001375
VERSION     KCVT01001375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15497:7457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78900.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          117 c          126 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcgccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga ggccaggcca
      241 gtctccacag ctgttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatttctgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa ttcaaacgag
//
LOCUS       KCVT01001376             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14812:3194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001376
VERSION     KCVT01001376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14812:3194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78901.1"
                     /translation="CLQFKTYPNSF"
     J_segment       390..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           98 a          119 c          109 g          102 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatctctt gccgggcaag
      181 tcagggtatt agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctcagct
      241 cctcatctat gctgcatcca gtttggccgg tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattctctc tcaccatcac cagcctgcag cctgaagatt ttgcaactta
      361 tttctgtctg cagtttaaaa cttacccgaa cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01001377             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5309:7071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001377
VERSION     KCVT01001377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5309:7071"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78902.1"
                     /translation="CMQGIEYPPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          119 c          125 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ctattactgc atgcaaggta tagagtatcc tccgtggacg ttcggccaag
      421 ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01001378             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:4467:10775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001378
VERSION     KCVT01001378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4467:10775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..427
                     /note="immunoglobulin light chain variable region"
     V_region        107..427
     V_segment       107..390
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78903.1"
                     /translation="CLQYKTFPFTF"
     J_segment       398..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>431
                     /gene="IGKC"
BASE COUNT          107 a          119 c          104 g          101 t
ORIGIN      
        1 acatggggct tgcaggagtc agacacagtc aggacacagc atggacatga gggcccccgc
       61 tcatctccta gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac
      121 tcagtctccg tcttccctgt ctgcatctgt gggagacact gtcaccatca cttgccggac
      181 aagtcaaggt attaccaatt atttacattg gtttcagcag aaaccaggga gagcccctaa
      241 gctcctgatc tatgaaacat tcagtttgac aagtggggtc ccatcaaggt tcagcggcag
      301 tgcatctggg acagaattca ctctcaccat cagcggcctg cagcctgaag attttgcaac
      361 ttatcactgt ctacagtata aaactttccc gttcaccttt ggccagggga ccaaactgga
      421 gatcaaagga g
//
LOCUS       KCVT01001379             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12686:7925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001379
VERSION     KCVT01001379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12686:7925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..311
                     /note="immunoglobulin light chain variable region"
     V_region        6..311
     V_segment       6..273
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <251..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78904.1"
                     /translation="CLQFKTFPYSF"
     J_segment       274..311
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>314
                     /gene="IGKC"
BASE COUNT           74 a           82 c           76 g           82 t
ORIGIN      
        1 atgggagtct ccatcttccc tgtctgcatc tgtaggagac actgtcacca tctcttgccg
       61 ggcaagtcag ggtattagca gttctttaag ttggtttcag cagaaaccag ggaaagcccc
      121 taagctcctc atctatgctg catccacttt ggccggtggg gtcccatcaa ggttcagcgg
      181 cagtggatct gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc
      241 aacttattac tgtctacagt ttaaaacttt cccgtacagt tttggccagg ggaccaaagt
      301 ggagatcaaa cgag
//
LOCUS       KCVT01001380             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14068:18064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001380
VERSION     KCVT01001380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14068:18064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78905.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          120 c          106 g           89 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg aaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001381             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17443:9986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001381
VERSION     KCVT01001381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17443:9986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78906.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc attttggaaa gtggggtccc atcaaggttc agcgccagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001382             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14869:13974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001382
VERSION     KCVT01001382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14869:13974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78907.1"
                     /translation="CLQYKSYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          106 a          113 c          102 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 tagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc ctcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa agttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01001383             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:15716:4072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001383
VERSION     KCVT01001383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:15716:4072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78908.1"
                     /translation="CQQYDSDPRTF"
     J_segment       392..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          119 c          113 g           90 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaactgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac cttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001384             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23662:2423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001384
VERSION     KCVT01001384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23662:2423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..387
                     /note="immunoglobulin light chain variable region"
     V_region        66..387
     V_segment       66..349
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78909.1"
                     /translation="CQQYDSFPFTF"
     J_segment       350..387
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>390
                     /gene="IGKC"
BASE COUNT           97 a          107 c           91 g           95 t
ORIGIN      
        1 acatggggag ggtccccgct cagctcctgg ggctcctgct gctctggctc ccaggtgcca
       61 gatgtgacat tcagatgacc cagtctccat cctccctgtc tgcttctgta ggagacagag
      121 tcaccatcac ttgccgggca agtcaggaca ttagcagtta tttaaactgg tatcagcaga
      181 aaccggggaa agcccctaaa ctcctgatct attatacaaa tcgtttggaa actggggtcc
      241 catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc
      301 aacctgaaga ttttgcaact tattactgtc aacagtatga tagttttcca ttcactttcg
      361 gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01001385             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:19506:16240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001385
VERSION     KCVT01001385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19506:16240"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78910.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgtgtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01001386             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14739:11970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001386
VERSION     KCVT01001386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14739:11970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78911.1"
                     /translation="CMQALDFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          124 c          121 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gcggatgttg gggtttatta ctgcatgcaa gctctagact ttcccctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01001387             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12657:17530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001387
VERSION     KCVT01001387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12657:17530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78912.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          114 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctctctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001388             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11402:8749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001388
VERSION     KCVT01001388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11402:8749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78913.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tacgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001389             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16408:18197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001389
VERSION     KCVT01001389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16408:18197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78914.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcaacagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaattt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001390             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:5419:15011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001390
VERSION     KCVT01001390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:5419:15011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78915.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001391             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9901:8237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001391
VERSION     KCVT01001391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9901:8237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78916.1"
                     /translation="CLQGYSVPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          118 c          108 g           97 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgctt cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaaactc ctcagcgcct
      241 gatctatgct gcagccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggttatagtg tcccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01001392             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11824:8083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001392
VERSION     KCVT01001392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11824:8083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78917.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          117 c          108 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcat agccagccac
      181 gatataaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct
      301 gggacagatt tcactctcag catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001393             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:19274:16983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001393
VERSION     KCVT01001393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:19274:16983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78918.1"
                     /translation="CQQVYSNPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          115 c          104 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgtccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gccagaacat
      181 ttggagttat ttagcgtggt atgagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctacatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaactt attactgtca
      361 acaggtttat agtaacccat tcactttcgg ccccgggacc aaactggaaa tcaaacgag
//
LOCUS       KCVT01001394             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14516:14305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001394
VERSION     KCVT01001394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14516:14305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78919.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          126 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttggtt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cgctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001395             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18549:7693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001395
VERSION     KCVT01001395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18549:7693"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78920.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacacgta cttggactgg tacctgcaga agccgggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagact ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001396             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15899:11235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001396
VERSION     KCVT01001396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15899:11235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78921.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggcccaggga
      421 ccaaggtgga catcaaacga g
//
LOCUS       KCVT01001397             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:25092:11616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001397
VERSION     KCVT01001397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:25092:11616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78922.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001398             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15079:12894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001398
VERSION     KCVT01001398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15079:12894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78923.1"
                     /translation="CMQALDFPYSF"
     J_segment       400..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctgctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctacagaa gccaggccag
      241 tctccacagc tcttgatttt tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac taatttcaca ctgaaaatca gcagtgtgga ggctgaggat
      361 gttggggtct attactgcat gcaagctcta gactttcctt acagttttgg ccaggggacc
      421 acagtggaga ttaaacgag
//
LOCUS       KCVT01001399             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24314:8348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001399
VERSION     KCVT01001399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24314:8348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78924.1"
                     /translation="CVQSSHIPFTF"
     J_segment       403..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggat ccagtgggga aattctgatg acccagactc
      121 cactctccct gcccgtcaca cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggattg gtacctccag aagccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat ccgcagagtg caggctgagg
      361 atgttggagt ttattactgc gtgcaatctt cacacattcc gttcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001400             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:25332:14484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001400
VERSION     KCVT01001400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25332:14484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..364
                     /note="immunoglobulin light chain variable region"
     V_region        43..364
     V_segment       43..322
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78925.1"
                     /translation="CQQYDSDSLTF"
     J_segment       327..364
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           90 a           98 c           93 g           86 t
ORIGIN      
        1 acatggggac tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag
       61 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgact
      121 caggacattc gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaagccc
      181 ttgatctatt acgcgtccac tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      301 tactgtcaac agtatgacag tgattcgctc actttcggtg gagggaccaa ggtggagatc
      361 aaacgag
//
LOCUS       KCVT01001401             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19703:14610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001401
VERSION     KCVT01001401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19703:14610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78926.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001402             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13972:20925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001402
VERSION     KCVT01001402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13972:20925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78927.1"
                     /translation="CLHYNSDPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          108 c          106 g          102 t
ORIGIN      
        1 acatggggag aagttagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tctgtaagag acagagtcac cttcacttgc agggcaagtc
      181 agggcattac aactttttta aattggtgtc agcagaaatc aggaaaaact cctaagcgcc
      241 tgatctgtgt tgaatacagt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacagg tttcactctc accatcagca gcctgcagcc tgaagatttt acaacttatt
      361 cctgtcttca ttataacagt gacccgtgga cgttcggcca aggaaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001403             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25911:9845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001403
VERSION     KCVT01001403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25911:9845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78928.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tccagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggc ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001404             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20339:4864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001404
VERSION     KCVT01001404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20339:4864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78929.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          116 g          110 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct tgagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001405             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22906:11308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001405
VERSION     KCVT01001405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22906:11308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78930.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c           98 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01001406             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24539:19576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001406
VERSION     KCVT01001406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24539:19576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78931.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g           98 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagtcggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01001407             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9918:10625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001407
VERSION     KCVT01001407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9918:10625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..392
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78932.1"
                     /translation="CLQSKNSPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          104 a          115 c          114 g          100 t
ORIGIN      
        1 acatgggagg agcagcctct agttcagctc tcagaaatgg ggtcctgggc tcctttcctg
       61 tggatcctcc tgctctgtgc tccaggctgc aatggggaca ttgtgctgac ccagtctcca
      121 gcctctttgg ccgtgtctcc agggcagagg gccaccatcg tctgcagagc cagtgagagt
      181 gtcaatgtct ttggaataaa cctcattcac tggtatcagc agaaaccagg acaacctcct
      241 aaacccctga tttaccaagc atccaataaa gaaactgggg tcccagccag gttcagcggc
      301 agtgggtctg ggaccgattt caccctcaca attaatcctg tggaagctga cgatgctgca
      361 gattattact gtctgcagag taagaattct ccgtggacgt ttggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01001408             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:5675:12854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001408
VERSION     KCVT01001408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5675:12854"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78933.1"
                     /translation="CQQYDSDPRTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          117 c          113 g           89 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggcgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagagttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg cgcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001409             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5174:18765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001409
VERSION     KCVT01001409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5174:18765"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..362
                     /note="immunoglobulin light chain variable region"
     V_region        82..362
     V_segment       82..322
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78934.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       330..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           98 a           88 c           92 g           87 t
ORIGIN      
        1 acatggggag aaccactcag gacacaggat ggacatgacg gtccccgctt atctcctggg
       61 gctccttctg ctctggctcc caggagacaa agtcaccatc acttgcaggg caagtcagga
      121 cattggtaat tatttaaatt ggtatcagca gaaaccagga aaagctccta aggtcctgat
      181 ctatggtgta tccaatttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagatctt actctcacca tcagcagcct gcagcctgaa gattttgcaa cgtattattg
      301 tcaaacgttt aaaagttacc tttcggtccc tttcggcgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01001410             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:7954:15022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001410
VERSION     KCVT01001410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7954:15022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78935.1"
                     /translation="CMQGTHLPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          119 c          116 g          101 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatctagt ggggatgttg tgatgactca gtctcccctc
      121 tccctgccca tcacccctgg acaaccggcc tccatctcct gcaggtctag ttacagcctt
      181 atacacagtg atgggacaac ctacttgaat tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatcaggt ttctaaccgg gactctgggg tcccagtcag attcagcggc
      301 agtggggcag ggacagattt cacacttgga atcagcagag tggaggctga ggatgttgga
      361 gtttattact gcatgcaagg tacacacctt ccgtacagtt ttggccaggg gaccaaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01001411             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14097:21914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001411
VERSION     KCVT01001411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14097:21914"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78936.1"
                     /translation="CMQGIEYPYSF"
     J_segment       405..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          114 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tgttgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaaggta tagagtatcc gtatagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001412             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10788:14052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001412
VERSION     KCVT01001412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10788:14052"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78937.1"
                     /translation="CQQYNSDPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccagg tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gctgagacca gggaaagccc cgaaggcctt
      241 aatctattac gcgaccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaggattttg caacttattt
      361 ctgtcaacag tataacagtg acccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001413             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:12923:8752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001413
VERSION     KCVT01001413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12923:8752"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78938.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgtgctgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgtaggtct agtcagagcc
      181 tcttggatag tgaggatgga aatacctatt tggaatggca ccggcagatg ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcag cagagtggag gctgaggatg
      361 ttggggttta ttactgcatg caagctctag agtttcctct gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01001414             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:15276:5440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001414
VERSION     KCVT01001414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15276:5440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78939.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacgttcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001415             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24891:7966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001415
VERSION     KCVT01001415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24891:7966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78940.1"
                     /translation="CQQVHTNPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          105 g           99 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtct
      121 ccatctgcct tgtctgcatc tgtaggagac agagtcacca tctcttgccg ggcaagccag
      181 aacatttgga gttatttagc gtggtatgag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgcta catccagatt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattctgc aacttattac
      361 tgtcaacagg ttcatactaa cccattcact ttcggccccg ggaccaaact ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001416             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14859:12620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001416
VERSION     KCVT01001416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14859:12620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78941.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          110 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001417             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8720:13405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001417
VERSION     KCVT01001417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8720:13405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78942.1"
                     /translation="CMQALEFPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          106 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttgggtt ttattattgc atgcaagctc tagagtttcc tcccactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001418             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:2078:10299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001418
VERSION     KCVT01001418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2078:10299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78943.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          120 c          107 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cacatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001419             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4715:12953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001419
VERSION     KCVT01001419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4715:12953"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78944.1"
                     /translation="CQQVYSNPAF"
     J_segment       386..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          101 a          112 c          110 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccaggt gacccagtct
      121 ccatctgcct tgtctgcatc tgtaggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata ggaatttagc gtggtatcag cagagaccag ggaaagcccc taagctcctc
      241 atctatgctg catccaggtt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcaac ctacagcctg aagattctgc aatttattac
      361 tgtcaacagg tttatagtaa cccggcgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01001420             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19488:9005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001420
VERSION     KCVT01001420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19488:9005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78945.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgccg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001421             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18342:11720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001421
VERSION     KCVT01001421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18342:11720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78946.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          118 c          126 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagcggg gacgtagtga tgacccagac
      121 tccactctcc ctgtccgtca cccttggaga gtcggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatggtgagg atggaaacac ctacttggaa tggtatttgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctgg
      361 ggatgttggg gtttatcact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001422             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20775:13478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001422
VERSION     KCVT01001422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20775:13478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78947.1"
                     /translation="CQQHDNSPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          116 c          110 g           86 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagagta
      181 ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga taattccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001423             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12859:14973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001423
VERSION     KCVT01001423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12859:14973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78948.1"
                     /translation="CMQGLEYPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          117 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgcggat ggaaaaacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttattactgc atgcaaggtt tagagtatcc atacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001424             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16796:14744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001424
VERSION     KCVT01001424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16796:14744"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..287
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78949.1"
                     /translation="CQQNSNWPLTF"
     J_segment       288..324
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>327
                     /gene="IGKC"
BASE COUNT           78 a           90 c           92 g           67 t
ORIGIN      
        1 acatgggagt gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagaggca
       61 ccctctcctg cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcaaaaac
      121 ctgggcgggc tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag
      181 acaggttcag tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc
      241 ctgaagatgt tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg
      301 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001425             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20570:10797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001425
VERSION     KCVT01001425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20570:10797"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78950.1"
                     /translation="CLQGYITPYSF"
     J_segment       367..404
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           95 a          108 c          107 g           97 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tccttctgct
       61 ctggctccca ggtgccagat gtgacttcca gatgacccag tctccatctt ccctgtctgc
      121 atcggtagga gacagagtca ccatcacttg ccgggcaagt caggacatta gcgatttttt
      181 aagttggtat cagcagaaac caggaaaacc tcctaagcgc ctgatttatg ctgcatccag
      241 tttgcaaagt ggggtcccgt caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcagc ctgaagattt tgcggcttat tactgtctac agggttatat
      361 taccccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01001426             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18227:17748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001426
VERSION     KCVT01001426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18227:17748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78951.1"
                     /translation="CQQHADSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           88 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggta
      181 ttagcaactg gttggcctgg tatcaacaga gaccagggaa agcccctaag gtcctgattt
      241 ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaacc ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tttcgctaca tattactgtc
      361 aacagcatgc tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001427             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:4107:12607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001427
VERSION     KCVT01001427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4107:12607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..345
                     /note="immunoglobulin light chain variable region"
     V_region        128..345
     V_segment       128..305
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <282..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78952.1"
                     /translation="CMQALEFPPFTF"
     J_segment       308..345
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>348
                     /gene="IGKC"
BASE COUNT           78 a           96 c           90 g           84 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagaatc
      121 cactctccct gcagaagcca ggccagtctc cacagctctt gatttatgag gtttccaacc
      181 gggcctctgg agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga
      241 aaatcagcag agtggaggct gaggatgttg gggtttatta ttgcatgcaa gctctagagt
      301 ttcctccatt cactttcggc cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01001428             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7035:7548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001428
VERSION     KCVT01001428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7035:7548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78953.1"
                     /translation="CQHSFRSPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          107 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccgtcact tgcagggcta gtgagagcgt
      181 taagaccaaa ttacattggt atcaacagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctggaac
      301 agatttcaat ctcaccatca gcagcctgca gcctgaagat gttgcaactt tttactgtca
      361 gcatagtttt cgttccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001429             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14118:21572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001429
VERSION     KCVT01001429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14118:21572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..413
                     /note="immunoglobulin light chain variable region"
     V_region        74..413
     V_segment       74..376
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <353..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78954.1"
                     /translation="CMQALEFPLTF"
     J_segment       377..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT           91 a          108 c          120 g           97 t
ORIGIN      
        1 acatggggac acaatgaggc tccctgctca gctcctggga ctgctaatgc tctggctccc
       61 tggatccagc ggggacattg tgatgaccca gactccactc tccctgcccg tcacctttgg
      121 agagccggcc tccatctcct gcaggtctag tcagagcctc ttggatggtg aggatggaaa
      181 cacgtacttg gaatggtatt tgcagaagcc aggccagtct ccacaactct tgatttatga
      241 ggtttccaag cgggcctctg gagtcccaga caggttcagt ggcagtgggt caggcactga
      301 tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggggtttatc actgcatgca
      361 agctctagag tttcctctca ctttcggcgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001430             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13611:14738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001430
VERSION     KCVT01001430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13611:14738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..431
                     /note="immunoglobulin light chain variable region"
     V_region        96..431
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78955.1"
                     /translation="CMQALEFPRTF"
     J_segment       400..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>438
                     /gene="IGKC"
BASE COUNT           94 a          122 c          118 g          104 t
ORIGIN      
        1 atggggatca cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctgtatcca gtggtgacat tgtgatgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagtc
      181 tcttggatag tgcggatgga aacacctatt tggactggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtctccg accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg ctcagacact gatttcacac tgaaaatcag cagagtggag gctgaagatg
      361 ttgggattta ttactgcatg caagctctag agtttcctcg gacgttcggc caggggacca
      421 aggtggaaat cgaacgag
//
LOCUS       KCVT01001431             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18393:17900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001431
VERSION     KCVT01001431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18393:17900"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78956.1"
                     /translation="CQQGYSYPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           98 a          117 c          112 g           95 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 ctcctccctg tccgcatctg tgggagacgc agtcacgatc acttgccagg cgagtcaagg
      181 cattggcaat aacttaaatt ggtttcagca gaaaccaggg aaagccccta aactcctgat
      241 ctataagaca tccagtttgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagttacc cgtggacgtt cggccaaggg gccaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001432             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:25578:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001432
VERSION     KCVT01001432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25578:7995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..387
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78957.1"
                     /translation="CLQSKNSPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          114 c          112 g          100 t
ORIGIN      
        1 acatggggag cctctagttc agctctcaga aatggggtcc tgggctcctt tcctgtggat
       61 cctcctgctc tgtgctccag gctgcaatgg ggacattgtg ctgacccagt ctccagcctc
      121 tttggccgtg tctccagggc agagggccac catcgtctgc agagccagtg agagtgtcaa
      181 tgtctttgga ataaacctca ttcactggta tcagcagaaa ccaggacaac ctcctaaacc
      241 cctgatttac caagcatcca ataaagaaac tggggtccca gccaggttca gcggcagtgg
      301 gtctgggacc gatttcaccc tcacaattaa tcctgtggaa gctgacgatg ctgcagatta
      361 ttactgtctg cagagtaaga attctccgtg gacgtttggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001433             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19416:11143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001433
VERSION     KCVT01001433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19416:11143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..387
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78958.1"
                     /translation="CQQYDDYPWTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT          102 a          117 c          115 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacaaagtc accatcactt gccatgccag
      181 tcagggtatt agtagtcggt tagtctggta tcagcagaaa ccagggaaag cccctaagcc
      241 cctgatgtat gctgcatcca gtttacacag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggacg gattacactc tcaccatcag cagcctgcag cctgaagatt ttgcatctta
      361 ttactgtcaa cagtatgatg attacccgtg gacgttcggc caagggacca aggtggaaat
      421 caagcgag
//
LOCUS       KCVT01001434             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:9154:4407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001434
VERSION     KCVT01001434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9154:4407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78959.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ttagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001435             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12764:14648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001435
VERSION     KCVT01001435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12764:14648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78960.1"
                     /translation="CQQHNTYPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           94 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatctttta cgcgtccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 gctgtcaaca gcataatact tatccgtaca cttttggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001436             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17879:9004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001436
VERSION     KCVT01001436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17879:9004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78961.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagta ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagagacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001437             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10662:3574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001437
VERSION     KCVT01001437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10662:3574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..440
                     /note="immunoglobulin light chain variable region"
     V_region        104..440
     V_segment       104..402
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78962.1"
                     /translation="CLQDIQFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           92 a          123 c          121 g          107 t
ORIGIN      
        1 acatgggggg actgatcagg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctgggg ctgctggtgc tctggctccc tgggaccagt ggggatattg tgttgactca
      121 gactccagtc tccctgtccg tcacccctgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc cttcaaacta atggaaacac ctatttgttt tggtacctgc agaagccagg
      241 ccagtctcca caactcctga tctacttggg ttccaaccgg gcctctggaa tcccagacag
      301 gttcagtggc agtgggtcag gcactgattt cacactgaaa atcagccggg tggaggctga
      361 agatgttggg gtttattact gcttgcaaga tatacagttt ccgctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001438             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24884:16969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001438
VERSION     KCVT01001438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24884:16969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78963.1"
                     /translation="CQQGYTYPFTF"
     J_segment       381..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          121 c          104 g           97 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgctcctgta ggagacacag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcagaaa tttaaattgg tatcagcaga aaccagggaa agcccctaaa ctcctgctct
      241 atagggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tacttaccct ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01001439             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:26722:14817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001439
VERSION     KCVT01001439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:26722:14817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..394
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78964.1"
                     /translation="CQQNSNWPLTF"
     J_segment       395..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          104 a          127 c          116 g           87 t
ORIGIN      
        1 acatgggggc tctggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc
       61 agcacagctt ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat
      121 gacgcagtct ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag
      181 ggccagtcag agtgtcagca acagcttagc ctggtaccaa caaaaacctg ggcagcctcc
      241 caggctcctc atctatggtg catccagcag ggccactggc atcccagaca ggttcagagg
      301 cagtgggtct gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc
      361 agtttattat tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01001440             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16776:9135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001440
VERSION     KCVT01001440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16776:9135"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78965.1"
                     /translation="CLQGYSAPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          118 c          107 g           98 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgctt cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaaactc ctcagcacct
      241 gatctatgct gcatccagtt tggagagtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggttatagtg ccccattcac tttcggcccc gggaccaaac tggatttcaa
      421 acgag
//
LOCUS       KCVT01001441             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23225:3382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001441
VERSION     KCVT01001441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23225:3382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78966.1"
                     /translation="CQQYDSFPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          107 a          116 c          102 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttatttaaa ctggtatcag cagaaaccgg ggaaagcccc taaactcctg
      241 atctattata caaatcgttt ggaaactggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt atgatagttt tccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01001442             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20694:3560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001442
VERSION     KCVT01001442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20694:3560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78967.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          125 g          103 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagttcc cttggacgtt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001443             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17627:18379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001443
VERSION     KCVT01001443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17627:18379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78968.1"
                     /translation="CIQSLEFPWTF"
     J_segment       406..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          111 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccactg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccttctcctg taggtctagt
      181 cacagcctct tggatagtga ggatggaaat atccatttgg attggtatct gcagaagcca
      241 ggccagtctc cacacctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggtttagtg gcagtgggtc agacactgat ttcacactga aaatcagcag ggtggaggct
      361 gaggatgttg gggtttacta ctgcatacaa tctcttgagt ttccttggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01001444             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14496:11920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001444
VERSION     KCVT01001444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14496:11920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78969.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          116 c          107 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattaacaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaggtcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcaacaacc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001445             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19596:3973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001445
VERSION     KCVT01001445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19596:3973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78970.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          113 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcaa ctgagaccag ggaaagcccc gaaggcctta
      241 atctattacg cgaccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aggattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001446             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17964:19172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001446
VERSION     KCVT01001446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17964:19172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..356
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78971.1"
                     /translation="CQQDFGWPPTF"
     J_segment       359..393
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           92 a          113 c          106 g           85 t
ORIGIN      
        1 acatggggac catggaagct ccagcacagc ttctcttcct cctgctactc tggatcccag
       61 ataccaccgg agaaatagtg atgacgcagt ctccagccat tctgtctttg tctccagggg
      121 aaagagccac cctctcctgc agggccagtc agactgttgg cagcgcctta gcctggtacc
      181 agcagaaacc tgggcagact cacaaactcc tcatttatgg tgcatccagc agggccaccg
      241 gcatcccaga caggttcagt ggcagtgggt ctggaacaga gttcactctc accatcagta
      301 gtccggagcc tgaggatgtt ggagtttatt actgtcagca ggattttggc tggcctccga
      361 cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001447             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14919:11111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001447
VERSION     KCVT01001447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14919:11111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78972.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001448             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:6459:12853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001448
VERSION     KCVT01001448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6459:12853"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78973.1"
                     /translation="CQQGYRYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtgggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattgacat taatttaaat tactatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atcccgtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagatac ccgtacagtt ttggccaggg gaccaaagtg gagatgaaac
      421 gag
//
LOCUS       KCVT01001449             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:25712:8351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001449
VERSION     KCVT01001449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25712:8351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..381
                     /note="immunoglobulin light chain variable region"
     V_region        64..381
     V_segment       64..339
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78974.1"
                     /translation="CQQGYNYPWTF"
     J_segment       348..381
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>388
                     /gene="IGKC"
BASE COUNT           90 a          109 c           98 g           91 t
ORIGIN      
        1 acatgggggg tccccgctca gctccttggg ctcctgctgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgacgca gtctccatcc tccctgtccg catctgtggg agacacagtc
      121 acgatctctt gccaggcgag tcaaggcatt gacaataatt taaattggtt tcagcagaca
      181 ccagggaaag cccctaaact cctgatctat aagacatcca gtttgcagag tgggattccc
      241 tctcggttca gcggcagtgg atctgggacg gatttcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgccactta ttactgtcaa cagggttata attacccgtg gacgttcggc
      361 caagggacca aggtggaaat ccaacgag
//
LOCUS       KCVT01001450             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5576:6270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001450
VERSION     KCVT01001450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5576:6270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78975.1"
                     /translation="CQQHDGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          119 c          107 g           88 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagcctggt atcagcagag accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acaacatgat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01001451             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11574:16845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001451
VERSION     KCVT01001451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11574:16845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78976.1"
                     /translation="CQQDYNWPPTF"
     J_segment       389..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccggccac cctgtctttg tctccagggg aaagagccac cctgtcctgc agggccagtc
      181 agagtgttgg cagcacctta acctggtacc aacacaaacc tgggcaggct cccaagctcc
      241 tcatctatgg tgcatccagc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattataac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 gacgag
//
LOCUS       KCVT01001452             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5621:9861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001452
VERSION     KCVT01001452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5621:9861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78977.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtccctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001453             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19306:6995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001453
VERSION     KCVT01001453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19306:6995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78978.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgttggg cgactcagta
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001454             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9329:3562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001454
VERSION     KCVT01001454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9329:3562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78979.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          118 c          123 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactgtcc ctgcccatca cccttggaga gccggcctcc atctcctgtg ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001455             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16003:4503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001455
VERSION     KCVT01001455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16003:4503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78980.1"
                     /translation="CQQGYNTPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          115 c          117 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 gatattagca gctggttagc ctggtatcag ctgaagccgg ggaaagcccc taaactcttg
      241 atctataagg cgtccagttt ggcaagaggg gtcccatcga ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagcctg aagattttgc atcttattat
      361 tgtcaacagg gttacaatac cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001456             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25602:15212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001456
VERSION     KCVT01001456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25602:15212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78981.1"
                     /translation="CQQYNSEPRTF"
     J_segment       409..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          123 c          119 g           95 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgagtc agggcattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaaccc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtataacagt gagccgcgca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001457             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:13331:11486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001457
VERSION     KCVT01001457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13331:11486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78982.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          120 c          110 g           89 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc aacagagacc ggggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001458             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12867:11648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001458
VERSION     KCVT01001458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12867:11648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..422
                     /note="immunoglobulin light chain variable region"
     V_region        95..422
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78983.1"
                     /translation="CQQRNGYPYMISF"
     J_segment       388..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          111 c          112 g           99 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagttgatac agtctccatc
      121 ctccctgtct gcgtctgtag gagacagagt caccatcact tgtcgggcaa gtcaggacat
      181 taacagttat ttagcctggt atcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tagggcgtcc agtttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagttt attactgtca
      361 acagcggaat ggttacccgt acatgatcag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001459             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19843:20210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001459
VERSION     KCVT01001459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19843:20210"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78984.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          105 a          125 c          112 g           85 t
ORIGIN      
        1 acatggggga aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcaacagctt agcctggtac caacaaaaac ctgggcagcc tcccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag aggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01001460             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17672:14287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001460
VERSION     KCVT01001460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17672:14287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78985.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001461             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19583:10632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001461
VERSION     KCVT01001461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19583:10632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78986.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tggtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca actcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001462             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11081:14437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001462
VERSION     KCVT01001462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11081:14437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..383
                     /note="immunoglobulin light chain variable region"
     V_region        44..383
     V_segment       44..346
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78987.1"
                     /translation="CMQSLEIPPSF"
     J_segment       352..383
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           83 a           99 c          112 g           92 t
ORIGIN      
        1 acatggggga ctgctaatgc tctggctccc tgggtccagt ggggacattg tgatgacgca
       61 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      121 tcagagcctc ttggatagtg gggatggaaa cacctatttg gattggtacc tgcagaagcc
      181 aggccagtct ccacagctct tgatttatga ggtttccacc cgggcctctg gagtcccaga
      241 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      301 tgaggatgtt ggcgtttatt actgcatgca atctctagag attcctccca gtttcggtgg
      361 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001463             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14355:22506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001463
VERSION     KCVT01001463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14355:22506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78988.1"
                     /translation="CQQHNSYPLAF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           94 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatttatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ttgggacaga tttcactctc accatcagca gcctgcaggc tgaagatttt gctacttatt
      361 tctgtcaaca gcataatagt tacccgctcg ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001464             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21632:21767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001464
VERSION     KCVT01001464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21632:21767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78989.1"
                     /translation="CLQGDTAPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           96 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccactcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattaa cgattattta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 taatctatgc tgcatctagt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcagtttatt
      361 actgtctaca gggtgatact gccccgttca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001465             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9326:18822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001465
VERSION     KCVT01001465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9326:18822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..333
                     /note="immunoglobulin light chain variable region"
     V_region        20..333
     V_segment       20..298
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78990.1"
                     /translation="CQQGHSYPWTF"
     J_segment       304..333
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        334..>344
                     /gene="IGKC"
BASE COUNT           86 a           90 c           89 g           79 t
ORIGIN      
        1 acatgggggt gccagatgtg acatccagat gacgcagtct ccatcctccc tgtccgcatc
       61 tgtaggagac acagtcacga tcacttgcca gtcgagtcta ggcattggca aatttttaaa
      121 ttggtatcag cagaaaccag ggaaagcccc caaactcctg atctataggg catccagttt
      181 gcaaactggg attccctctc ggttcagcgg cagtggatct gggacggatt tcactctcac
      241 catcagcagc ctgcagcctg aagattttgc cgcttattac tgtcaacagg gtcatagtta
      301 cccgtggacg ttcggccaag ggaccaaggt ggagatgaaa cgag
//
LOCUS       KCVT01001466             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17014:13460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001466
VERSION     KCVT01001466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17014:13460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78991.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001467             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12297:13145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001467
VERSION     KCVT01001467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12297:13145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78992.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagtcac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001468             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:25562:14431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001468
VERSION     KCVT01001468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25562:14431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78993.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          117 c          121 g          106 t
ORIGIN      
        1 atggggtgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagagtcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgagatttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcacagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001469             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20439:12293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001469
VERSION     KCVT01001469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20439:12293"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78994.1"
                     /translation="CMQALEFPYSF"
     J_segment       400..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta ttgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcatggat agtggggatg taaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacat ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cggatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tacagttttg gccaggggac
      421 cagagtggag atcaaacgag
//
LOCUS       KCVT01001470             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14988:11439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001470
VERSION     KCVT01001470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14988:11439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..375
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78995.1"
                     /translation="CQQGYGFPFTF"
     J_segment       381..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           98 a          119 c          102 g          102 t
ORIGIN      
        1 acatggggtc agtctcagtc aggacacagc atggacatga gggtccccgc tcagctcctt
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac gcagtctcca
      121 tcctccctgt ccgcatctgt aggagacaca gtcgcgatca cttgcctggc gagtcaaggc
      181 attggcaata atttaaattg gtatcagcag aaaccaggga aagcccctaa actcctgatc
      241 tatacggcat ccaatttaca tggtgggatt ccctctcggt tcagcggcag tggatctggg
      301 acggatttca ctctcaccat caacagcctg cagcctgaag attttgccac ttattactgt
      361 caacagggtt atggttttcc attcactttc ggccccggga ccaaactgga tatcaaacga
      421 g
//
LOCUS       KCVT01001471             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14123:10095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001471
VERSION     KCVT01001471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14123:10095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78996.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          125 c          112 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat actgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacat ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt ggctcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01001472             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16929:18642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001472
VERSION     KCVT01001472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16929:18642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78997.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc agccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001473             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20233:8031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001473
VERSION     KCVT01001473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20233:8031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78998.1"
                     /translation="CEQYNSLPYTF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          113 c          106 g           97 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacgtt aacatttatt taaattggta tcaccagaaa ccggggaaag cccctaagct
      241 cctgatctat tatacaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta
      361 ttactgtgaa caatacaata gtttaccgta cacttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01001474             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22696:13294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001474
VERSION     KCVT01001474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22696:13294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV78999.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          102 a          111 c          106 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001475             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:5219:4603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001475
VERSION     KCVT01001475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5219:4603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79000.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01001476             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14464:4530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001476
VERSION     KCVT01001476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14464:4530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79001.1"
                     /translation="CQQYNSGPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          105 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg gcccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01001477             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13012:3577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001477
VERSION     KCVT01001477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13012:3577"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79002.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          125 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga catcgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacgt atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tacgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001478             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16056:18326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001478
VERSION     KCVT01001478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16056:18326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79003.1"
                     /translation="CMQGLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          117 c          126 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttccacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 gctctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggttg gagacaccta tttggagtgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtgtc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001479             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13311:14777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001479
VERSION     KCVT01001479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13311:14777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79004.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          121 c          115 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgacgatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001480             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17597:7586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001480
VERSION     KCVT01001480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17597:7586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79005.1"
                     /translation="CQQGYNTPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          114 c          115 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcaggatat
      181 tagcagctgg ttagcctggt atcagctgaa gccggggaaa gcccctaaac tcttgatcta
      241 taaggcgtcc agtttggcaa gaggggtccc atcgaggttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgcatctt attattgtca
      361 acagggttac aataccccgt ggacgttcgg cctagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001481             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7363:4701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001481
VERSION     KCVT01001481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7363:4701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79006.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcat tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001482             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14108:18723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001482
VERSION     KCVT01001482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14108:18723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79007.1"
                     /translation="CQQYNSLPWTF"
     J_segment       380..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          113 c          108 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt acgatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccctcact tgccgggcaa gtcaggacat
      181 tagcactttt ttaaattggt atcaacagag accggggaaa gcccctaagc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcactg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttacctt ggacgttcgg ccagggggcc agggtggaaa tcaaacgag
//
LOCUS       KCVT01001483             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11870:16802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001483
VERSION     KCVT01001483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11870:16802"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79008.1"
                     /translation="CQQHNSYPPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          120 c          106 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat
      181 tagcaatgat ttagcctggt atcagcagaa gccagggaaa gccccgaagc ccctgatcta
      241 tttcgcatcc aatttggaaa ctggggtccc atcagggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat agttaccctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001484             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:22258:7691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001484
VERSION     KCVT01001484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22258:7691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79009.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          104 a          127 c          120 g           87 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag
      121 tgctgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg
      241 ctcccagact cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca
      301 gtggcagtgg gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagata
      361 ttgcacttta ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01001485             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:2962:7530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001485
VERSION     KCVT01001485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:2962:7530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79010.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcagctcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001486             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14117:2803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001486
VERSION     KCVT01001486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14117:2803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79011.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccattttgg aaagtggggt cccatcaagg ttcagcgcca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001487             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11667:5705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001487
VERSION     KCVT01001487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11667:5705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79012.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01001488             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11429:12754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001488
VERSION     KCVT01001488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11429:12754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79013.1"
                     /translation="CQQYTSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          120 c          106 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggatat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 acgttagcag tcatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttatcact
      361 gtcaacagta cactagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001489             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19560:6338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001489
VERSION     KCVT01001489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19560:6338"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79014.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          102 a          125 c          110 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga cagtgaggat gaaaacacgt atttggaatg gtacgtgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat caacagagtg gagactgagg
      361 atcttggaat ttattactgc atgcaagctc tagaatttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001490             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21028:9716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001490
VERSION     KCVT01001490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21028:9716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79015.1"
                     /translation="CQKYSSFPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          125 c          107 g           94 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccagactcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagat ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagaag tatagtagtt tcccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01001491             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:7778:14257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001491
VERSION     KCVT01001491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7778:14257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..429
                     /note="immunoglobulin light chain variable region"
     V_region        94..429
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79016.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..429
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaagggg
      421 agatcaaacg ag
//
LOCUS       KCVT01001492             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8328:3767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001492
VERSION     KCVT01001492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8328:3767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79017.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 gcgag
//
LOCUS       KCVT01001493             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20885:17419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001493
VERSION     KCVT01001493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20885:17419"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79018.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggaggc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001494             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10962:7610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001494
VERSION     KCVT01001494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10962:7610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79019.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggatcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001495             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16963:4244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001495
VERSION     KCVT01001495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16963:4244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..374
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79020.1"
                     /translation="CQQYYSFPITF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          100 a          113 c          115 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggatcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtgggag acaaagtcac catcacttgc cgagccagtc
      181 agggtattaa cacctggtta atttggtatc agcagaaacc agggaaggcc cctaaggccc
      241 tgatctataa ggcatccagt ttgcaaggtg gggtcccttc caggttcagc ggcagtggat
      301 ctggggcaga cttcactctc accatcacca acctgcagcc tgaagatttt ggaatttatt
      361 actgtcaaca atattatagt tttccgatca ctttcggtgg ggggaccaag gtggagatca
      421 ggcgag
//
LOCUS       KCVT01001496             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20908:14820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001496
VERSION     KCVT01001496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20908:14820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79021.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001497             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18934:5650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001497
VERSION     KCVT01001497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18934:5650"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79022.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001498             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16843:13541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001498
VERSION     KCVT01001498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16843:13541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79023.1"
                     /translation="CQQDFDWPPTF"
     J_segment       392..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          102 a          126 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaggaactg ctcagttagg acccagaggg aaccatggaa gctccagcac
       61 agcttctctt cctcctgcta ctctggatcc cagataccac cggagaagtt gtgatgacgc
      121 agtctccagc caccctgtct ttgtctccag gggaaagagc caccctctcc tgcagggcca
      181 gtcagagtgt tggcaacacc ttaacctggt accagcacaa acctgggcag gctcccaagc
      241 tcctcctcta tggtgcatcc accagggcca ccggcatccc agacaggttc agtgccagtg
      301 ggtctggaac agagtttact ctcaccatca gcagcctgga gcctgaagat gttggaattt
      361 attactgtca gcaggatttt gactggcctc cgacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01001499             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:24406:19176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001499
VERSION     KCVT01001499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:24406:19176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79024.1"
                     /translation="CQQGDSYPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          112 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcagacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 ttcctccctg tctgcatctg tgggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagagat tatttaaatt ggtatcagca gcaaccgggg aaagccccta aactcctgat
      241 gtattatgca aacagtctgg caagtggagt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagggt gacagttatc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001500             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7010:9462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001500
VERSION     KCVT01001500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7010:9462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    151..295
                     /note="immunoglobulin light chain variable region"
     V_region        151..295
     V_segment       151..258
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <235..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79025.1"
                     /translation="CMQALEFPLTF"
     J_segment       259..295
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>298
                     /gene="IGKC"
BASE COUNT           71 a           73 c           86 g           68 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc aggagagtgt cacagagcag gacaggttca gtggcagtgg gtcagacact
      181 gatttcacac tgaaaatcag tagagtggag gatgaggatg ttgggattta ttactgcatg
      241 caagctctag agtttcctct cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01001501             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12413:18505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001501
VERSION     KCVT01001501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12413:18505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79026.1"
                     /translation="CQQYNSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001502             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17289:4336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001502
VERSION     KCVT01001502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17289:4336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..242
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79027.1"
                     /translation="CQQYDSDSLTF"
     J_segment       247..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           76 a           69 c           78 g           64 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg tcgggcgact caggacattc gcagttattt
       61 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac
      121 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      241 tgattcgctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001503             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20605:3808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001503
VERSION     KCVT01001503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20605:3808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79028.1"
                     /translation="CQQYNSYPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          118 c          106 g           96 t
ORIGIN      
        1 acatgggagg aatcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc agttatttag cctggtatca gcagaaacca gggaaagccc ctaagcgcct
      241 gatctatgct gcatccactt tacaaagtgg ggtcccatca agcttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctacagcct gaagattttg caacttatta
      361 ctgtcaacag tataatagtt atccgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001504             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7987:10596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001504
VERSION     KCVT01001504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7987:10596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79029.1"
                     /translation="CQQGNSNPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          109 c          114 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagta gttatttaaa ttggtatcag cagagaccgg ggaaagcccc taagctcctg
      241 atctattatg caaagagttt ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagtagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagg gtaatagtaa tcctctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001505             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22020:12329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001505
VERSION     KCVT01001505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22020:12329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79030.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaactgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001506             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14506:7990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001506
VERSION     KCVT01001506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14506:7990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79031.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          127 c          110 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga ctttactctc accatcagca gcctggagtc tgaagatgtt gcaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001507             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16983:3502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001507
VERSION     KCVT01001507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16983:3502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79032.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          127 c          112 g           86 t
ORIGIN      
        1 acagggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcccccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001508             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21076:3912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001508
VERSION     KCVT01001508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21076:3912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..423
                     /note="immunoglobulin light chain variable region"
     V_region        100..423
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79033.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       393..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>430
                     /gene="IGKC"
BASE COUNT          101 a          116 c          112 g          101 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagtt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcaagtcag
      181 gacattggca attatttagc ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctataagg cgtccagttt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agtttattac
      361 tgtcaacagc gtaatagtta cccgtacatg tgcagttttg gcccggggac caaagtggag
      421 atccgacgag
//
LOCUS       KCVT01001509             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16575:9123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001509
VERSION     KCVT01001509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16575:9123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    51..372
                     /note="immunoglobulin light chain variable region"
     V_region        51..372
     V_segment       51..334
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79034.1"
                     /translation="CQQHDNAPWTF"
     J_segment       335..372
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>375
                     /gene="IGKC"
BASE COUNT           95 a          101 c          100 g           79 t
ORIGIN      
        1 acatggggct cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga
       61 tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca
      121 gagccagtca gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc
      181 ctaagctcct gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg
      241 gaagtggatc tgggacagat ttcactctca gcatcagcag cctgcagcct gaagatatcg
      301 caacatatta ctgtcagcag catgacaatg ccccgtggac gttcggccaa gggaccaagg
      361 tggaaatcaa acgag
//
LOCUS       KCVT01001510             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24411:5346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001510
VERSION     KCVT01001510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24411:5346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79035.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001511             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16412:8616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001511
VERSION     KCVT01001511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16412:8616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79036.1"
                     /translation="CQHGYGIQLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          114 c          108 g           97 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagctt ggacatgagg gcccccactc agctcctggg
       61 gttcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagatagagt caccatctct tgccaggcga gtcaggacat
      181 tagcaatgat ttagcctggt atcagcaaaa acaggggaaa gcccctaggc tcctgctcta
      241 taaggcatcc gctttgcaaa atggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agatttcact ctcaccatca acagcctgca gcctgaagat tttgcaactt attattgtca
      361 gcatggttat ggtatccagc tcactttcgg tggagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01001512             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17074:2282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001512
VERSION     KCVT01001512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17074:2282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..357
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79037.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          115 c          116 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcggctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tgtccatctc ctgccaagcc agaccagatg
      181 tacatggtga aataccttgg atccggataa accttgaaca aagacttgaa ccccttttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagcccggtt catcaccaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01001513             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20018:7591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001513
VERSION     KCVT01001513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20018:7591"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79038.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          109 c          103 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccgggcaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgaaacatac agtttggtaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcatt ctcagcatca gcagcctgca gcctgaagat tttgcaacct attactgtct
      361 acagtataaa agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001514             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21674:7061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001514
VERSION     KCVT01001514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21674:7061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79039.1"
                     /translation="CQQHDNAPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          115 c          114 g           85 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagtgta
      181 ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcagcatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 agcagcatga caatgccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001515             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14546:16817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001515
VERSION     KCVT01001515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14546:16817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79040.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccaaccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001516             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:26163:9070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001516
VERSION     KCVT01001516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26163:9070"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79041.1"
                     /translation="CMQSLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctctag agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001517             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13896:12001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001517
VERSION     KCVT01001517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13896:12001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79042.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          123 c          117 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01001518             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19511:8829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001518
VERSION     KCVT01001518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19511:8829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79043.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          120 c          105 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacacatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001519             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19478:6141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001519
VERSION     KCVT01001519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19478:6141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79044.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001520             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16140:17991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001520
VERSION     KCVT01001520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16140:17991"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79045.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          124 c          116 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgataa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cattcacctt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01001521             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14271:14131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001521
VERSION     KCVT01001521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14271:14131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79046.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          125 c          117 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacacttat aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcacc ttcggccccg
      421 ggaccagact ggatgtcaaa cgag
//
LOCUS       KCVT01001522             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19495:18330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001522
VERSION     KCVT01001522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19495:18330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79047.1"
                     /translation="CLQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cttgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001523             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11752:15710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001523
VERSION     KCVT01001523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11752:15710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79048.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgagt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001524             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:2597:15006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001524
VERSION     KCVT01001524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:2597:15006"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79049.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttaagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001525             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7616:10451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001525
VERSION     KCVT01001525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7616:10451"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79050.1"
                     /translation="CQQYNSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cacatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaga gccccgaagc ccttgatcta
      241 ttacgcgtcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagac tttgcaactt attactgtca
      361 acagtataac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001526             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22519:16673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001526
VERSION     KCVT01001526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22519:16673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79051.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgagatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttgcactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttaatt tacgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001527             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14931:12584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001527
VERSION     KCVT01001527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14931:12584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79052.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcaa ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001528             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22481:17544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001528
VERSION     KCVT01001528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22481:17544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..414
                     /note="immunoglobulin light chain variable region"
     V_region        94..414
     V_segment       94..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79053.1"
                     /translation="CLQYKSYPLTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>418
                     /gene="IGKC"
BASE COUNT          107 a          112 c          101 g           98 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcagggtatt
      181 agcaatcatt taaattggtt tcagcagaaa ccagggaaag cccctagact cctgatctat
      241 gcttcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg atctgagaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta tcactgtcta
      361 cagtataaaa gttaccctct cactttcggc ggagggacca aggtggagat caaaagag
//
LOCUS       KCVT01001529             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20490:10998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001529
VERSION     KCVT01001529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20490:10998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79054.1"
                     /translation="CQQYDSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          118 c          113 g           90 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggcg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001530             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12003:9559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001530
VERSION     KCVT01001530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12003:9559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79055.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          123 g           97 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagagaggat ggaaacacct atttggactg gtacctgcag aggccaggcc
      241 agactcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atcttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001531             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23535:14129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001531
VERSION     KCVT01001531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23535:14129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79056.1"
                     /translation="CLQGDTAPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggcaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcacactcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gtgatactgc cccgttcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001532             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9528:20536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001532
VERSION     KCVT01001532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9528:20536"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..414
                     /note="immunoglobulin light chain variable region"
     V_region        94..414
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79057.1"
                     /translation="CLQYKSYPFTF"
     J_segment       378..414
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>418
                     /gene="IGKC"
BASE COUNT          105 a          112 c          100 g          101 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcttgctgc tctggctccc aggtgccaga tgtgacatcc aactgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcagggtatt
      181 agtagttatt taaattggtt tcagcagaaa acagggaagg cccctaagct cctgatctat
      241 gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg atttgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa gttacccatt cactttcggc cccgggacca aactggacat caaaggag
//
LOCUS       KCVT01001533             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20613:9533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001533
VERSION     KCVT01001533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20613:9533"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79058.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          108 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 atattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggaactg
      301 ggacagattt cactctcacc atcaccagcc tggagcctga agatttcgca acatattatt
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001534             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18072:9409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001534
VERSION     KCVT01001534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18072:9409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79059.1"
                     /translation="CLQGDTAPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggcaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gtgatactgc cccgttcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001535             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18327:6997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001535
VERSION     KCVT01001535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18327:6997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..381
                     /note="immunoglobulin light chain variable region"
     V_region        44..381
     V_segment       44..346
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79060.1"
                     /translation="CMQALEFPFTF"
     J_segment       348..381
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>386
                     /gene="IGKC"
BASE COUNT           82 a          100 c          110 g           94 t
ORIGIN      
        1 acatggggga ctgctaatgc tctggctccc tggatccact ggggacattg ttatgaccca
       61 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      121 tcagagcctc tttgatattg aggaggggac cacctatttg gaatggtacc tgcagaggcc
      181 tggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      241 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcaaca gagtggaggc
      301 tgaggatggt ggggtttatt actgcatgca agctctagag tttcctttca ctttcggcgg
      361 agggaccaag gtggagatca agcgag
//
LOCUS       KCVT01001536             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9951:22262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001536
VERSION     KCVT01001536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9951:22262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79061.1"
                     /translation="CMQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggccttcat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tacaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001537             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8971:8078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001537
VERSION     KCVT01001537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8971:8078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79062.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggagcctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001538             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9195:20290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001538
VERSION     KCVT01001538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9195:20290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79063.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          115 c          109 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 cggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtag gtatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattttgc aaatcgtttg ggaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacctga ggattttgcg acttattatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001539             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14600:12216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001539
VERSION     KCVT01001539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14600:12216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79064.1"
                     /translation="CQQYNSLPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          108 c          110 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcaa gtcagggcat
      181 tagcgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgtaggtt attactgtca
      361 acagtataat agtttaccgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001540             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15727:19632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001540
VERSION     KCVT01001540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15727:19632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    54..298
                     /note="immunoglobulin light chain variable region"
     V_region        54..298
     V_segment       54..256
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <238..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79065.1"
                     /translation="CQQYDSDSLTF"
     J_segment       261..298
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        299..>301
                     /gene="IGKC"
BASE COUNT           80 a           75 c           82 g           64 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcaggac
       61 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgag gcccttgatc
      121 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      181 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      241 caacaatatg acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      301 g
//
LOCUS       KCVT01001541             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15718:15622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001541
VERSION     KCVT01001541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15718:15622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79066.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc attggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001542             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18996:8168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001542
VERSION     KCVT01001542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18996:8168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79067.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          126 c          110 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccctctgca tagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatccat aaagttacca atcgggaatc tggggcccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01001543             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14872:16687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001543
VERSION     KCVT01001543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14872:16687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79068.1"
                     /translation="CLQFKTFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          118 c          107 g          102 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atctcttgcc gggcaagtca
      181 gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc ctaagctcct
      241 catctatgct gcatccactt tggccggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagac ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tttaaaactt tcccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001544             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21530:6203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001544
VERSION     KCVT01001544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21530:6203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79069.1"
                     /translation="CMQALEFPWTF"
     J_segment       240..277
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           73 a           58 c           83 g           66 t
ORIGIN      
        1 acatgggggt ctagtcagag tctcttggat agtgaggatg gaaacaccta tttggaatgg
       61 tacctgcaga agccaggcca gtctccacaa ctcttgattt atgaggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      181 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct agaatttccg
      241 tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001545             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:9911:9327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001545
VERSION     KCVT01001545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9911:9327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79070.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          126 c          112 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacaaccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaaactcc
      241 ttgtccatag tgcattcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001546             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15283:5021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001546
VERSION     KCVT01001546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15283:5021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79071.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcat cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001547             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:25292:16137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001547
VERSION     KCVT01001547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:25292:16137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79072.1"
                     /translation="CMQALEFPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctgcatcc agtggggaca ttgtgatgac ccagagtcca
      121 ctctccctgc ccgtcagcct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctctgggata gtgaggaagg gaatacctat ttggaatggt acctccagaa gccaggccag
      241 tctccacaga tattgattta tgcggtttct aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgcaaatca gcagagtgga gcctgaggat
      361 gttgggattt attactgcat gcaagctcta gaatttccat tcactttcgg ccccgggacc
      421 aaactggaca tcaaacgag
//
LOCUS       KCVT01001548             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24045:10575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001548
VERSION     KCVT01001548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24045:10575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..281
                     /note="immunoglobulin light chain variable region"
     V_region        5..281
     V_segment       5..243
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79073.1"
                     /translation="CQQYNSDPFTF"
     J_segment       244..281
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>284
                     /gene="IGKC"
BASE COUNT           81 a           71 c           68 g           64 t
ORIGIN      
        1 acatggggac agagtaacca tcacttgtcg ggcgagtcag gacataagaa gttatttagc
       61 gtggtatcag cagaaaccag gcaaaccccc gaagcccttg atctattacg catccgtttt
      121 ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct gggacagaat tcactctcac
      181 catcagcagt ctgcagcctg aggattttgc aacttattac tgtcaacaat ataacagtga
      241 cccattcact ttcggccccg ggaccaaact ggataccaaa cgag
//
LOCUS       KCVT01001549             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15520:8037
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001549
VERSION     KCVT01001549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15520:8037"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79074.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctag ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001550             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:3273:16483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001550
VERSION     KCVT01001550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:3273:16483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..250
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79075.1"
                     /translation="CQQHNGYPPTF"
     J_segment       263..297
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           84 a           75 c           75 g           66 t
ORIGIN      
        1 acatggggtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
       61 ttacgaatga tttagcctgg tatcaacaga aaccaggtaa agccccgaag cccctgatct
      121 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      181 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      241 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01001551             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:15979:17545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001551
VERSION     KCVT01001551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15979:17545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..381
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79076.1"
                     /translation="CQQYDDYPWTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          100 a          117 c          112 g           93 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagttcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacaa agtcaccatc acttgccatg ccagtcaggg
      181 tattagtggt cggttagtct ggtatcagca gaaaccaggg aaagccccta agcccctgat
      241 gtatgctgcg tccagtttac acagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacggattac actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gatgattacc cgtggacgtt cggccaaggg accaaggtgg aaatcaaccg
      421 ag
//
LOCUS       KCVT01001552             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14886:9843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001552
VERSION     KCVT01001552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14886:9843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79077.1"
                     /translation="CQQHDNSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          113 a          120 c          108 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      181 ccacgatata aataactggt tggcctggta tcaacagaaa ccaggaaaag cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt tcgcaacata
      361 ttactgtcaa cagcatgata attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001553             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:26737:8291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001553
VERSION     KCVT01001553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26737:8291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..342
                     /note="immunoglobulin light chain variable region"
     V_region        23..342
     V_segment       23..306
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79078.1"
                     /translation="CQQYDDYPWTF"
     J_segment       307..342
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>347
                     /gene="IGKC"
BASE COUNT           87 a           93 c           88 g           79 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
       61 atctgtagga gacaaagtca ccatcacttg ccatgccagt cagggtatta gtagtcggtt
      121 agtctggtat cagcagaaac cagggaaagc ccctaagccc ctgatgtatg ctgcatccag
      181 tttacacagt ggggtcccat caaggttcag cggcagtgga tctgggacgg attacactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgatga
      301 ttacccgtgg acgttcggcc aagggaccaa ggtggaaatc aagcgag
//
LOCUS       KCVT01001554             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17775:18165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001554
VERSION     KCVT01001554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17775:18165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    141..480
                     /note="immunoglobulin light chain variable region"
     V_region        141..480
     V_segment       141..442
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <420..>452
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79079.1"
                     /translation="CMQALQFPWTF"
     J_segment       443..480
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        481..>483
                     /gene="IGKC"
BASE COUNT          108 a          129 c          129 g          117 t
ORIGIN      
        1 acatgggggt gagtgtgaga taaaagctca gcactaacct tgccttgact gatcacgact
       61 cctcaggtca ccttctcaca atgaggctcc ctgctcagct cctgggactg ctaatgctct
      121 ggctccctgg atccagtggg gacattgtga tgacccagac tccactctcc ctgcccgtca
      181 cccttggaga gccggcctcc atctcctgca ggtctagtca gagcctcttg gatagtgagg
      241 atggaaacac ctatttggaa tggtacctac agaggccagg ccagtctcca cacctcttga
      301 tttatgagtt ttccaatcgg gcctctggag tcccagacag gttcagtggc agtgggtcag
      361 acactgattt cactctgaat atcagcagag tggaggctga ggatgttggg gtttattact
      421 gcatgcaagc tctacaattt ccgtggacgt tcggccaagg gaccaaggtg gagatcaaac
      481 gag
//
LOCUS       KCVT01001555             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10094:7890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001555
VERSION     KCVT01001555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10094:7890"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79080.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001556             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11932:14335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001556
VERSION     KCVT01001556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11932:14335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79081.1"
                     /translation="CQQYNSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          114 c          108 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggcctc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gcagaaacca ggaaaagccc cgaaggcctt
      241 gatctattac gcatccattt tagaaagtgc ggtaccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag ccttcagtct gacgattttg caacttatta
      361 ctgtcaacag tataacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001557             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10387:14072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001557
VERSION     KCVT01001557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10387:14072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79082.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tttattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01001558             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17877:18537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001558
VERSION     KCVT01001558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17877:18537"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..332
                     /note="immunoglobulin light chain variable region"
     V_region        128..332
     V_segment       128..294
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <272..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79083.1"
                     /translation="CMQGIEYPYSF"
     J_segment       295..332
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>335
                     /gene="IGKC"
BASE COUNT           77 a           86 c           93 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccca ggccagtctc cacagccctt gatttatgag gtttccaacc gggcctctgg
      181 agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag
      241 agtggaggct gaggatgttg gggtttatta ctgcatgcaa ggtatagagt atccgtacag
      301 ttttggccag gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01001559             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10985:21628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001559
VERSION     KCVT01001559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10985:21628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..317
                     /note="immunoglobulin light chain variable region"
     V_region        120..317
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79084.1"
                     /translation="CMQSLDFPLTF"
     J_segment       282..317
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>322
                     /gene="IGKC"
BASE COUNT           71 a           83 c           87 g           81 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggagactgag
      241 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      301 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01001560             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11321:11814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001560
VERSION     KCVT01001560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11321:11814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79085.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          109 c          107 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aggttcctga
      241 tctattatgt aaaccgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaagctga agattttgca acttattatt
      361 gtcaacaata taacagttta ccgtacagtt tcggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001561             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10784:6096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001561
VERSION     KCVT01001561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10784:6096"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79086.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctacatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001562             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13740:15107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001562
VERSION     KCVT01001562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13740:15107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79087.1"
                     /translation="CQQYDSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          116 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agccaggaca cagcttggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattagc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctatttc gcatccgttt tggaaagtgg cgtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001563             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18061:19608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001563
VERSION     KCVT01001563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18061:19608"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..427
                     /note="immunoglobulin light chain variable region"
     V_region        95..427
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79088.1"
                     /translation="CGQGAHLPWTF"
     J_segment       394..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>434
                     /gene="IGKC"
BASE COUNT           93 a          117 c          123 g          101 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgatgactc agtctccact
      121 ctccctgtcc atcattcctg gacagccggc ctccatgtcc tgcaggtcta gtcaaagcct
      181 tgtacacagt tatggagata cctatttgag ttggtatcac cagaagccag gccaacctcc
      241 aaggcgcctg atttatcagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggcc gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 ggtttatttc tgcggacaag gtgcacacct tccgtggacg ttcggccaag ggaccaaggt
      421 ggaaatccaa cgag
//
LOCUS       KCVT01001564             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15224:18593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001564
VERSION     KCVT01001564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15224:18593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79089.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          117 c          105 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001565             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:21721:5172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001565
VERSION     KCVT01001565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21721:5172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79090.1"
                     /translation="CQQHDNSPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          119 c          110 g           90 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct ctctgcatct gtagtagaca gagtcaccat cacttgcaga gccagtcagg
      181 gtgttagcga ctggttggcc tggtatcaac agagaccagg gaaagcccct aaactcctga
      241 tctatagggc gtccaatttg gatacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgct acatattact
      361 gtcaacagca tgataattcc cctccgacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001566             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23584:7381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001566
VERSION     KCVT01001566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23584:7381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79091.1"
                     /translation="CQHYNSLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          110 a          112 c          105 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatat aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tgcaacctga ggattttgca acttattact
      361 gtcaacatta taatagttta cctcggacgt tcggccaagg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01001567             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22350:6893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001567
VERSION     KCVT01001567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22350:6893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79092.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          113 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggattg gttcctacag aggccaggcc
      241 agtctccaca gctcttgatt tatgacattt ccaaccgggc ctctggagtc ccagacaggt
      301 tcattggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001568             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:27204:20892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001568
VERSION     KCVT01001568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:27204:20892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79093.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga ccggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001569             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:4701:8855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001569
VERSION     KCVT01001569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4701:8855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79094.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtgggag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001570             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6726:10681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001570
VERSION     KCVT01001570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6726:10681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79095.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001571             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15438:8619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001571
VERSION     KCVT01001571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15438:8619"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..438
                     /note="immunoglobulin light chain variable region"
     V_region        103..438
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79096.1"
                     /translation="CMQALEFPRTF"
     J_segment       407..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>445
                     /gene="IGKC"
BASE COUNT           96 a          124 c          120 g          105 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct gtatccagtg gtgacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagtctct tggatagtgc ggatggaaac acctatttgg actggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtctccgacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtggctc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaagatgttg ggatttatta ctgcatgcaa gctctagagt ttcctcggac gttcggccag
      421 gggaccaagg tggaaatcga acgag
//
LOCUS       KCVT01001572             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18965:10500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001572
VERSION     KCVT01001572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18965:10500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79097.1"
                     /translation="CMQPLEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          105 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gttgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct ccagaagcca
      241 ggccagtctc cacatctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa cctctagagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01001573             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14404:12864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001573
VERSION     KCVT01001573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14404:12864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79098.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          109 c          109 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccatgg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001574             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14804:6171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001574
VERSION     KCVT01001574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14804:6171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79099.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          121 c          123 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattctg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaagcg ggcctctgga gtccccgaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001575             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24693:17342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001575
VERSION     KCVT01001575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24693:17342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79100.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          122 c          116 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagtgt agcctggtac cagcaaaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01001576             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:26648:15063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001576
VERSION     KCVT01001576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:26648:15063"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79101.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001577             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20396:20609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001577
VERSION     KCVT01001577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20396:20609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79102.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001578             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9547:18014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001578
VERSION     KCVT01001578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9547:18014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79103.1"
                     /translation="CMQSLEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggggg cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaga gctcttcatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaatctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001579             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20737:4329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001579
VERSION     KCVT01001579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20737:4329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..410
                     /note="immunoglobulin light chain variable region"
     V_region        95..410
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79104.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..410
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>419
                     /gene="IGKC"
BASE COUNT          107 a          116 c          103 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca acctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccgagcgag
//
LOCUS       KCVT01001580             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21367:14572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001580
VERSION     KCVT01001580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21367:14572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79105.1"
                     /translation="RQQGYSYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          120 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgcaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattggca atactttaaa ttggtatcaa cagaaaccgg ggaaagcccc tacactcctg
      241 atctataggg catccggttt gcaaagtggg actccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 cgtcaacagg gttatagtta tccgtacagt tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001581             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12462:4410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001581
VERSION     KCVT01001581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12462:4410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79106.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcagac
      421 gag
//
LOCUS       KCVT01001582             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17942:7884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001582
VERSION     KCVT01001582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17942:7884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79107.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccagag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggctt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001583             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:10633:2416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001583
VERSION     KCVT01001583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10633:2416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79108.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001584             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9630:17975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001584
VERSION     KCVT01001584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9630:17975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79109.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001585             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:26233:9922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001585
VERSION     KCVT01001585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:26233:9922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79110.1"
                     /translation="CQQYNSDPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          113 c          110 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccaggtga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattagaagt tatttagcgt ggtatcaact gagaccaggg aaagccccga aggccttaat
      241 ctattacgcg accattttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgag gattttgcaa cttatttctg
      361 tcaacagtat aacagtgacc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001586             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8753:6538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001586
VERSION     KCVT01001586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8753:6538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79111.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aacgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001587             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8761:11068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001587
VERSION     KCVT01001587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8761:11068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79112.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001588             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15126:12984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001588
VERSION     KCVT01001588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15126:12984"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79113.1"
                     /translation="CQQGYSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          119 c          108 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gcaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattggcaa tactttaaat tggtatcaac agaaaccggg gaaagcccct acactcctga
      241 tctatagggc atccggtttg caaagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttat ccgtacagtt ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01001589             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21915:10693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001589
VERSION     KCVT01001589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21915:10693"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79114.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001590             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15176:16274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001590
VERSION     KCVT01001590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15176:16274"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79115.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001591             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:12673:11457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001591
VERSION     KCVT01001591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12673:11457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79116.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatc tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001592             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21819:11455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001592
VERSION     KCVT01001592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21819:11455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79117.1"
                     /translation="CQQDYSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          120 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcatctta gcctggtacc accagaaacc tgggcaggct cccaagtccc
      241 tcatctatgg tgcaaccagt agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctagaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggcgtttatt
      361 actgtcagca ggattatagc tggccactca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001593             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22071:16993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001593
VERSION     KCVT01001593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22071:16993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..362
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79118.1"
                     /translation="CQQYDSDSLTF"
     J_segment       367..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           99 a          111 c          105 g           92 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctaggac tcctgctgct
       61 ctgtctccca ggtgccaaat gtgacatcca gatgacccag tctccatcct ccctgtctgc
      121 atctgtagga gacagagtca ccatcacttg tcgggcgact caggacattc gcagttattt
      181 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac
      241 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      361 tgattcgctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001594             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8506:13966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001594
VERSION     KCVT01001594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8506:13966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79119.1"
                     /translation="CQQGYTYLYSF"
     J_segment       382..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catccgccct gtccgcatct gttggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctaa
      241 tctataaggc atccactttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ctgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001595             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25597:17661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001595
VERSION     KCVT01001595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25597:17661"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79120.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa gtgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001596             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9153:8445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001596
VERSION     KCVT01001596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9153:8445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79121.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          118 c          100 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaacccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagtc tgcagcctga ggattttgca acttattact
      361 gtcaacaata taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01001597             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14648:17631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001597
VERSION     KCVT01001597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14648:17631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79122.1"
                     /translation="CQQGYSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          118 c          107 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgcag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcaatact ttaaattggt atcaacagaa accggggaaa gcccctacac tcctgatcta
      241 tagggcatcc ggtttgcaaa gtgggactcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttatccgt acagttttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01001598             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11294:4803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001598
VERSION     KCVT01001598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11294:4803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79123.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          118 c          104 g          101 t
ORIGIN      
        1 acatggggtg acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagac tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001599             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18893:7361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001599
VERSION     KCVT01001599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18893:7361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79124.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tacatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001600             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5372:8068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001600
VERSION     KCVT01001600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5372:8068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79125.1"
                     /translation="CMQTLEFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          108 t
ORIGIN      
        1 acatggggga tctgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccggt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gtaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gattggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca aactctagag tttcctctca ctttcggcgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001601             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12403:4994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001601
VERSION     KCVT01001601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12403:4994"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79126.1"
                     /translation="CQQGYSYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          118 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgcaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattggta atactttaaa ttggtatcaa cagaaaccgg ggaaagcccc tacactcctg
      241 atctataggg catccggttt gcaaagtggg actccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta tccgtacagt tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001602             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11817:16330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001602
VERSION     KCVT01001602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11817:16330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79127.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01001603             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:21380:8676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001603
VERSION     KCVT01001603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21380:8676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79128.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat cccctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001604             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11253:3954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001604
VERSION     KCVT01001604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11253:3954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79129.1"
                     /translation="CQQVYTKPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          105 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccctgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagtcat ttagcgtggt atcaacagaa accagggaaa gcccctaagc tcctgattta
      241 tgctgcatcc aaattacaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctaaccatca acagcctgca gcctgaagat tctgcagctt atttctgtca
      361 acaggtttat actaagccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001605             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17309:20496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001605
VERSION     KCVT01001605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17309:20496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..331
                     /note="immunoglobulin light chain variable region"
     V_region        10..331
     V_segment       10..293
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79130.1"
                     /translation="CLQYNSSPLTF"
     J_segment       294..331
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           86 a           90 c           83 g           75 t
ORIGIN      
        1 acatggggtg acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac
       61 acagtcacca tcacttgccg ggcgagtcag actattagca gctggttaga ctggtatcag
      121 cagaaaccag ggaaagcccc taacctcctg atctttaagg catccagttt gcaaagtggg
      181 gtcccctcaa ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc
      241 ctgcagcctg aagattttgc aacttattat tgtctacagt acaatagtag cccgctcact
      301 ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001606             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10560:13572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001606
VERSION     KCVT01001606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10560:13572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79131.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          123 c          121 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagggc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaagtgga aatcaaacga g
//
LOCUS       KCVT01001607             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9355:6424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001607
VERSION     KCVT01001607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9355:6424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79132.1"
                     /translation="CQQYNSGPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          117 c          100 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accagccaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtgccagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtggcccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01001608             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20771:19455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001608
VERSION     KCVT01001608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20771:19455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..378
                     /note="immunoglobulin light chain variable region"
     V_region        107..378
     V_segment       107..341
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79133.1"
                     /translation="CQQHDDSPRTF"
     J_segment       343..378
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>381
                     /gene="IGKC"
BASE COUNT          101 a          103 c          100 g           77 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga gtcaccatca
      121 cttgcatagc cagccacgat ataaataact ggttggcctg gtatcaacag aaaccaggaa
      181 aagcccctaa gctcctgatc tatagggcat ccaatttgga aacaggggtc ccatcgaggt
      241 tcagtggaag tggatctggg acagatttca ctctcaccat cagcagcctg cagcctgaag
      301 atttcgcaac atattactgt caacagcatg atgattcccc tcggacgttc ggccaaggga
      361 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001609             548 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7618:5345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001609
VERSION     KCVT01001609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 548)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7618:5345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    227..545
                     /note="immunoglobulin light chain variable region"
     V_region        227..545
     V_segment       227..509
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <488..>517
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79134.1"
                     /translation="CYQHSRGWAF"
     J_segment       510..545
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        546..>548
                     /gene="IGKC"
BASE COUNT          123 a          159 c          154 g          112 t
ORIGIN      
        1 acatggggtg ctcatttcag agaagaggag gcaggtggtc tctgcagctg gaagcccagc
       61 acttgcccca gctgctttgc atgtccctcc cagctgccct gctgtcgtat taatgccagg
      121 atcggagctc gaggaagagc tgctaggtta gtacccagaa ggaaccatgg aagccccagc
      181 tcagcttctc tgccttctgc tactctggct cccaggtacc accggacaaa ttatattgac
      241 acagtctcca gccaccctgt ctttggcacc aggggaaaga gccactctct cctgcagggc
      301 cagtgagaat gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag
      361 gctcctcgtc cacagtgcgt ccagcagggc cactgacatc ccagacaggt tcagtggcag
      421 tgggtctcgg acagagttca ccctcaccat cagcagtctg gagcctgaag atgttggagt
      481 ctattactgc tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat
      541 caaacgag
//
LOCUS       KCVT01001610             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12053:11775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001610
VERSION     KCVT01001610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12053:11775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-61"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79135.1"
                     /translation="CQQGYSYPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          123 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattgaca ataacttaaa ttggtatcag cagaaaccag ggaacgcccc tcaactcctg
      241 atctatgggg cattctattc ccaaagtggg attccctctc gcttcagcgg cagtgaatct
      301 gggacgggtt tctctctcac catcagcagc ctgcagcctg aagattttgc cacttactac
      361 tgtcaacagg gttatagtta ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001611             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11414:23666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001611
VERSION     KCVT01001611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11414:23666"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79136.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           96 a          127 c          113 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgccc tggatcccag ataccgccgg agaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaaactcc
      241 ttgtccatag tgcattcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001612             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18231:11823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001612
VERSION     KCVT01001612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18231:11823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79137.1"
                     /translation="CMQSIKDPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          101 a          121 c          111 g          106 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tccagtgggg atattgtgat gacccagacc
      121 ccactctcgg tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctcc atagtaatgg agacacctat ttacattggt accttcagag gtcaggccag
      241 tctccacggc tcctgatcta taaagtaacc aatcggctac ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 attggtgttt atttctgcat gcaaagtata aaagatccat tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01001613             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:23609:21032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001613
VERSION     KCVT01001613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23609:21032"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79138.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          124 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggaggc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001614             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23398:10245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001614
VERSION     KCVT01001614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23398:10245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79139.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g           87 t
ORIGIN      
        1 acatggggga ggaactgttc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001615             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11548:7112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001615
VERSION     KCVT01001615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11548:7112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79140.1"
                     /translation="CMQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           90 a          124 c          120 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgtttttgta cctgcagaag ccaggccagt
      241 ctccacaact cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaagatg
      361 ttggggttta ttactgcatg caagatatac agcttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01001616             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8691:9761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001616
VERSION     KCVT01001616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8691:9761"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79141.1"
                     /translation="CQQYNSDPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          110 c          110 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caattgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcagga
      181 cattaggaat tatttagcgt ggtatcagca gaaaccaggg aaagccccga aggccttgat
      241 ctattacaca tccattttgg aaaatggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcaggctgag gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001617             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16908:15507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001617
VERSION     KCVT01001617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16908:15507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79142.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct actgctctgg ctcccagata ccaccggaga aatagtactg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccagc agagacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccaggcag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa cagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001618             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6891:7546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001618
VERSION     KCVT01001618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6891:7546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..369
                     /note="immunoglobulin light chain variable region"
     V_region        185..369
     V_segment       185..331
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <309..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79143.1"
                     /translation="CMQALDFPWTF"
     J_segment       332..369
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>372
                     /gene="IGKC"
BASE COUNT           77 a          102 c          104 g           89 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgat ttatgaagtt tccgaccggg cctctggagt cccagacagg ttcagtggca
      241 gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg
      301 tttattactg catgcaagct ctggactttc cgtggacgtt cggccaaggg accaaggtgg
      361 aagtcaaacg ag
//
LOCUS       KCVT01001619             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12917:7292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001619
VERSION     KCVT01001619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12917:7292"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79144.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           95 a          126 c          114 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgcattcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accatcagca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001620             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18172:9246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001620
VERSION     KCVT01001620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18172:9246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79145.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgacaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccaaagtgga gattaaacga g
//
LOCUS       KCVT01001621             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14237:16655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001621
VERSION     KCVT01001621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14237:16655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79146.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc ggggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001622             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14445:16642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001622
VERSION     KCVT01001622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14445:16642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79147.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          118 c          110 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca ctggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttatttctg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001623             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6951:2441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001623
VERSION     KCVT01001623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6951:2441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79148.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 aggttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgca gatcaaacga g
//
LOCUS       KCVT01001624             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8826:14867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001624
VERSION     KCVT01001624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8826:14867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79149.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          124 c          120 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgttg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccttca tagtaatgga aacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacaact cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaagatg
      361 ttggggttta ttactgcttg caagatatac agcttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01001625             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16219:6315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001625
VERSION     KCVT01001625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16219:6315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79150.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgtg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatcttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001626             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20364:7294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001626
VERSION     KCVT01001626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20364:7294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79151.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          118 c          110 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattagcaa ctggttggcc tggtatcaac agagaccagg gaaagcccct aaggtcctga
      241 tttataggac atccaatttg gaaacagggg tcccatcaag gttcagtgga accggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgct acatattact
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001627             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5818:9503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001627
VERSION     KCVT01001627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5818:9503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..371
                     /note="immunoglobulin light chain variable region"
     V_region        50..371
     V_segment       50..333
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79152.1"
                     /translation="CQQHNTYPYTF"
     J_segment       334..371
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>374
                     /gene="IGKC"
BASE COUNT          100 a           99 c           94 g           81 t
ORIGIN      
        1 acatggggag gagtcagaac cactcagctg gctcccaggt gccagatgtg acatccagat
       61 gacccagtct ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg
      121 ggcaagtcag ggcattagta aggatttagc ctggtatcag cagaaaccag ggaaagcccc
      181 gaagcccctg atcttttacg catccaattt ggaaagtggg gtcccatcaa ggtgcagcgg
      241 cagtggatct gggacagatt tcactctcac catcagcagc ctgcagcctg aagattatgc
      301 aacttattac tgtcaacagc ataatactta cccgtacact tttggtcagg ggaccaaggt
      361 ggagatcaaa cgag
//
LOCUS       KCVT01001628             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10722:2942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001628
VERSION     KCVT01001628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10722:2942"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79153.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagttccct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001629             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8498:7611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001629
VERSION     KCVT01001629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8498:7611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..287
                     /note="immunoglobulin light chain variable region"
     V_region        14..287
     V_segment       14..249
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79154.1"
                     /translation="CQQYNSDPFTF"
     J_segment       250..287
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           78 a           73 c           71 g           68 t
ORIGIN      
        1 acatggggag tctgacccag tctccatcac ttgtcgggcg agtcaggaca taagaagtta
       61 tttagcgtgg tatcagcaga aaccaggcaa agccccgaag cccttgatct attacgcatc
      121 cgttttggaa agtggggtcc catcaaggtt cagtggcagt ggatctggga cagaattcac
      181 tctcaccatc agtagtctgc agcctgagga ttttgcaact tattactgtc aacagtataa
      241 cagtgaccca ttcactttcg gccccgggac caaactggat accaaacgag
//
LOCUS       KCVT01001630             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:12922:13877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001630
VERSION     KCVT01001630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12922:13877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79155.1"
                     /translation="CQQHNSYPLAF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgattta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatttgggac
      301 agatttcact ctcaccatca gcagcctgca ggctgaagat tttgctactt atttctgtca
      361 acagcataat agttacccgc tcgctttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001631             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23939:4415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001631
VERSION     KCVT01001631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23939:4415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..473
                     /note="immunoglobulin light chain variable region"
     V_region        137..473
     V_segment       137..435
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <413..>445
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79156.1"
                     /translation="CGQGTHLPLTF"
     J_segment       436..473
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        474..>476
                     /gene="IGKC"
BASE COUNT          112 a          121 c          141 g          102 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggtaagcgc agaagggaga tgagggagga gaatggggtg
      121 taaaggatcc agtggggatg ttgtgatgag tcagtctcca ctctccctgc ccatcacccc
      181 tggacagccg gcctccatct cctgcaggtc tagtcaaagc cttgtacaca tcactggaaa
      241 cacatacttg agttggtatc agcagaagtc aggccaacct ccaaggcgcc taatttatga
      301 ggtctctaac cgggactctg gggtcccaga cagattcagc ggcagtgggg cagggacaga
      361 tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggggtttatt attgcggtca
      421 aggtacacac cttccgctca ctttcggcgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001632             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15866:8742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001632
VERSION     KCVT01001632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15866:8742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79157.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc aacagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01001633             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25433:9716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001633
VERSION     KCVT01001633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25433:9716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79158.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          118 c          116 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cctgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001634             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18771:3619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001634
VERSION     KCVT01001634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18771:3619"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79159.1"
                     /translation="CQQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          111 c          105 g           99 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac gttcagatga cccagtctcc
      121 atcctacctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacgtt tatttaaatt ggtatcacca gaaaccgggg aaagccccta acctcctgat
      241 ctattatgca aatcgtttgg aaaatggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcga cttattactg
      361 tcaacagtat aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001635             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20311:7560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001635
VERSION     KCVT01001635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20311:7560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79160.1"
                     /translation="CLQHKSFPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          119 c           95 g           97 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtattaccaa ttatttacat tggtttcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatgaaac atccagtttg acaagtgggg tcccatcaag gttcagcggc agcgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaccctga agattttgca acttattact
      361 gtctacagca taaaagtttc ccgtacactt ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01001636             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19992:10999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001636
VERSION     KCVT01001636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19992:10999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79161.1"
                     /translation="CQQYNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattaccaat gatttagcct ggtatcagca gaagccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagtat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001637             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7401:6681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001637
VERSION     KCVT01001637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7401:6681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79162.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          101 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttagaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaggccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttcctaccgg gcctctggag tcccagagag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttagg gtttattact gcatgcaagc tctagaattt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001638             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12134:10908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001638
VERSION     KCVT01001638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12134:10908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79163.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          105 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaact atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01001639             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9380:15394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001639
VERSION     KCVT01001639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9380:15394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79164.1"
                     /translation="CMQGLEFPPTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          124 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtggcg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtggtga tggaaacacc tatttggaat ggttcctcca gaggccaggc
      241 cagtctccac acctcttgat ttatggggct tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc ctccgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001640             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8056:12075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001640
VERSION     KCVT01001640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8056:12075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79165.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggga ggaactactc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001641             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8377:20705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001641
VERSION     KCVT01001641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8377:20705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79166.1"
                     /translation="CIQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atacaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01001642             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25548:10450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001642
VERSION     KCVT01001642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25548:10450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79167.1"
                     /translation="CLQGDTAPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          113 c          114 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagaagtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcgttaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taaacgcctg
      241 atctatgctg catccagttt ggaaaggggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattat
      361 tgtctacagg gtgatactgc cccgttcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001643             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21414:9866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001643
VERSION     KCVT01001643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21414:9866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79168.1"
                     /translation="CQQYNSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          112 c          109 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001644             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14871:4366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001644
VERSION     KCVT01001644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14871:4366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79169.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           99 a          122 c          113 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctgggt ccagtgggga tattgtgatg acccagactc
      121 cactgtcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga tacacctatt tgcattggta cttgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01001645             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20066:19333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001645
VERSION     KCVT01001645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20066:19333"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79170.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tggtgaaaat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccgca gctcttgatc tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001646             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16891:1950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001646
VERSION     KCVT01001646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16891:1950"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..391
                     /note="immunoglobulin light chain variable region"
     V_region        70..391
     V_segment       70..344
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79171.1"
                     /translation="CQQHNNYSPTF"
     J_segment       357..391
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT           96 a          112 c           98 g           88 t
ORIGIN      
        1 acatgggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg gctcccaggt
       61 gccagatgtg acatccagat gacccagtct ccaccctccc tgtctgcatc tgtaggagac
      121 acagtcacca tcacttgtcg ggcaagtcag ggcattagca atgatttagc ctggtatcag
      181 ctgaaaccag ggaaagcccc gaagcccctg atctattacg catccaattt ggaaagtggg
      241 gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac catcagcagc
      301 ctgcagcctg aagattttgc aacttattac tgtcaacagc ataataatta ctctcccact
      361 ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001647             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9632:12586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001647
VERSION     KCVT01001647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9632:12586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79172.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          126 c          111 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acgtggtacc accacaaacc tgggcaggct cccaaactcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001648             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10469:4889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001648
VERSION     KCVT01001648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10469:4889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79173.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          123 c          121 g          103 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattga gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgc actggtacct gcagaagcca
      241 ggccagtctc cacagctctt aatttacgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01001649             385 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10170:17112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001649
VERSION     KCVT01001649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 385)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10170:17112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..382
                     /note="immunoglobulin light chain variable region"
     V_region        43..382
     V_segment       43..344
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <322..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79174.1"
                     /translation="CMQPLEFPWTF"
     J_segment       345..382
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>385
                     /gene="IGKC"
BASE COUNT           90 a           98 c          107 g           90 t
ORIGIN      
        1 acatggggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
       61 actccactct ccctgtccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      121 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct acagaagcca
      181 ggccagtctc cacagctctt gatttatgaa gtttccaacc gggcctctgg agtcccagac
      241 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      301 gaggatgttg gggtttatta ctgcatgcaa cctctagagt ttccgtggac gttcggccaa
      361 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01001650             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25509:4193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001650
VERSION     KCVT01001650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25509:4193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79175.1"
                     /translation="CQQNSNRPYTF"
     J_segment       397..434
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          125 c          120 g           90 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gattccaccg gagaagtagt
      121 gatgacgcag tctccagcca ccctgtcttt ctctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagtagttt agcctggtac cagcagaaac ctgggcagcc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acagattcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ccgaagatgt
      361 tgcagtttat ttttgtcagc agaatagtaa tcggccgtac acttttggcc aagggaccaa
      421 agtggagatc aaacgag
//
LOCUS       KCVT01001651             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6417:12845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001651
VERSION     KCVT01001651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6417:12845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79176.1"
                     /translation="CQQSYSNPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          112 c          108 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc ggtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagagttat agtaacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001652             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:23533:4622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001652
VERSION     KCVT01001652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23533:4622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79177.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          108 c          110 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggtcaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001653             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5621:17683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001653
VERSION     KCVT01001653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5621:17683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79178.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgtatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001654             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7796:13316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001654
VERSION     KCVT01001654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7796:13316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..246
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79179.1"
                     /translation="CQQNSNWPLTF"
     J_segment       247..283
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           71 a           79 c           80 g           56 t
ORIGIN      
        1 acatggggag aaagagccac cctctcctgc agggccagtc agagtgtcag cagcagctta
       61 gcctggtacc aacaaaaacc tgggcaggct cccaggctcc tcatctatgg tgcatccagc
      121 agggccactg gcatcccaga caggttcagt ggcagtgggt ctgggacaga cttcactctc
      181 accatcacca gcctggagcc cgaagatgtt gcagtttatt attgtcagca gaatagtaac
      241 tggcctctca ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001655             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16506:10382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001655
VERSION     KCVT01001655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16506:10382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79180.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgcagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaacatct atttggattg gtacctgcag aggccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001656             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22850:12758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001656
VERSION     KCVT01001656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22850:12758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79181.1"
                     /translation="CMQGLEFPPTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          124 c          121 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtggcg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtggtga tggaaacacc tatttggaat ggttcctcca gaggccaggc
      241 cagtctccac acctcttgat ttgtggggct tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc ctccgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001657             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14916:5597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001657
VERSION     KCVT01001657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14916:5597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79182.1"
                     /translation="CQKYISSPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          131 c          110 g           94 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaacttat
      121 attgactcag tctccagcca ccctgtctct gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcctctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagt ctgaagattt
      361 tgcagtatat tactgtcaga aatatattag ctccccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01001658             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17656:10848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001658
VERSION     KCVT01001658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17656:10848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79183.1"
                     /translation="CLQRSNWPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaaacc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctctg tctccagggg aaagagccac tctctcctgt agggccagtc
      181 agagtgtcag tagctactta gcctggtacc agcaaaaacc tgggcaggct cccaggctcc
      241 tcatctatac tgcatccacc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga cttcactctc accatcagca gcctggagcc tgaagatgtt ggagtttatt
      361 actgtctgca gcgtagtaac tggccgtgga cgttcggcca agggaccaag gtggaagtca
      421 aacgag
//
LOCUS       KCVT01001659             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4072:14215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001659
VERSION     KCVT01001659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4072:14215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..406
                     /note="immunoglobulin light chain variable region"
     V_region        89..406
     V_segment       89..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79184.1"
                     /translation="CQQYDSDPYSF"
     J_segment       373..406
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>413
                     /gene="IGKC"
BASE COUNT          102 a          110 c          109 g           92 t
ORIGIN      
        1 acatgggcag tcaggacaca gcatggacat gagggtcccc gctcagctcc taggactcct
       61 gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc catcctccct
      121 gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg gcattaggag
      181 ttatttagcg tggtatcagc agaaaccagg gaaagccccg aaggccttga tctattacac
      241 atccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcagcctga ggattttgca acttattact gtcaacagta
      361 tgacagtgac ccgtacagtt ttggccaggg gaccagagtg gagatccaac gag
//
LOCUS       KCVT01001660             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11368:13018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001660
VERSION     KCVT01001660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11368:13018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79185.1"
                     /translation="CIQSLEFPWTF"
     J_segment       313..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           80 a           87 c           98 g           87 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcct tctcctgtag gtctagtcac agcctcttgg atagtgagga tggaaatatc
      121 catttggatt ggtatctgca gaagccaggc cagtctccac acctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg tttagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagggt ggaggctgag gatgttgggg tttactactg catacaatct
      301 ctagagtttc cttggacgtt cggccagggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001661             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18877:14679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001661
VERSION     KCVT01001661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18877:14679"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..438
                     /note="immunoglobulin light chain variable region"
     V_region        101..438
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79186.1"
                     /translation="CMQSLDFPLTF"
     J_segment       403..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>443
                     /gene="IGKC"
BASE COUNT           96 a          122 c          118 g          107 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtta tcacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcctg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acacagattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcagtc tctagatttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaatc gag
//
LOCUS       KCVT01001662             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13067:2635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001662
VERSION     KCVT01001662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13067:2635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79187.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          108 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaacg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001663             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11279:9765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001663
VERSION     KCVT01001663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11279:9765"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79188.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          121 c          116 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 ccccttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001664             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10670:6207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001664
VERSION     KCVT01001664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10670:6207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79189.1"
                     /translation="CQHYISSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           96 a          127 c          111 g           92 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccaggcac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca ctatattagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gaggag
//
LOCUS       KCVT01001665             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16182:7772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001665
VERSION     KCVT01001665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16182:7772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79190.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          124 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcgcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgacaat cagcagagtg gaggctgagg
      361 atgttggggt gtattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaagcga g
//
LOCUS       KCVT01001666             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22978:8803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001666
VERSION     KCVT01001666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22978:8803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79191.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacctattac
      361 tgtcaacagt atgacagtga tccgttcact ttcggtgggg agaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01001667             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19686:18391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001667
VERSION     KCVT01001667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19686:18391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79192.1"
                     /translation="CQQYDSFPFTF"
     J_segment       379..413
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          106 a          115 c          100 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaactggt atcagcagaa accggggaaa gcccctaaac tcctgatcta
      241 ttatacaaat cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtatgat agttttccat tcactttcgg ccccgggacc aaactggata tcagacgag
//
LOCUS       KCVT01001668             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22668:2868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001668
VERSION     KCVT01001668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22668:2868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79193.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          125 c          112 g           85 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc aacagcttag cctggtacca acaaaaacct gggcagcctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagag gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001669             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13471:17122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001669
VERSION     KCVT01001669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13471:17122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79194.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttaac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001670             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6438:15707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001670
VERSION     KCVT01001670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6438:15707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79195.1"
                     /translation="CQQSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          119 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtccg
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc tgagctcctg
      241 atctatgctg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggggcagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttatttc
      361 tgtcagcaaa gttatgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001671             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10123:7277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001671
VERSION     KCVT01001671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10123:7277"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..368
                     /note="immunoglobulin light chain variable region"
     V_region        88..368
     V_segment       88..328
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79196.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       336..368
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT          100 a           89 c           94 g           88 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca caggatggac atgacggtcc ccgcttatct
       61 cctggggctc cttctgctct ggctcccagg agacaaagtc accatcactt gcagggcaag
      121 tcaggacatt ggtaattatt taaattggta tcagcagaaa ccaggaaaag ctcctaaggt
      181 cctgatctat ggtgtatcca atttacaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gatcttactc tcaccatcag cagcctgcag cctgaagatt ttgcaacgta
      301 ttattgtcaa acgtttaaaa gttacctttc ggtccctttc ggcggaggga ccaaggtgga
      361 gatcaaacga g
//
LOCUS       KCVT01001672             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21707:16876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001672
VERSION     KCVT01001672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21707:16876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79197.1"
                     /translation="CQQYDNDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctacagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacaat gacccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01001673             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23514:8197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001673
VERSION     KCVT01001673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23514:8197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79198.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gctctttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001674             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9263:15882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001674
VERSION     KCVT01001674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9263:15882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79199.1"
                     /translation="CQQYNSEPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          112 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg agccgcgcac tttcgttgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001675             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14802:17105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001675
VERSION     KCVT01001675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14802:17105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79200.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          125 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001676             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:8723:14433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001676
VERSION     KCVT01001676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8723:14433"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79201.1"
                     /translation="CMQGTHLPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          122 c          114 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccact ggggatgttg tcatgactca gtctccactc
      121 tccctggcca tcacccctgg acaaccggcc tccatctcct gcaggtctag ttacggcctt
      181 atacacagtg atgggaaaac ctacttgaat tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tctatcaggt ttctaaccgg gactctgggg tcccactcag attcagcggc
      301 agtggggcgg ggacagattt cacactggaa atcagcagag tggaggctga agatgttgga
      361 aattattact gcatgcaagg tacacacctt ccgtacagtt ttggccaggg gaccgaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01001677             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19580:12416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001677
VERSION     KCVT01001677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19580:12416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-82"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79202.1"
                     /translation="CMQGTHLPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           91 a          128 c          119 g          101 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgt tagtgctctg gctccctggg tccgctggcg acgctgtgct gacacagacc
      121 ccactctccc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctac atagaaatgg atacacctat ttgtactggt acctgcagaa gccgggccag
      241 tctccacagc tcctgatgta ttttgtttca aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgcgaatca gcagggtgga ggctgaggat
      361 attggcattt attattgcat gcaaggtaca caccttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001678             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22511:18146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001678
VERSION     KCVT01001678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22511:18146"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79203.1"
                     /translation="CQQDYSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          120 c          118 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcatctta gcctggtacc accagaaacc tgggcaggct cccaagtccc
      241 tcatctatgg tgcaaccagt agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggcgtttatt
      361 actgtcagca ggattatagc tggccactca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001679             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11875:12785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001679
VERSION     KCVT01001679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11875:12785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79204.1"
                     /translation="CLQYKSYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          103 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagcactttt ttaaattggt ttcagcagaa atcagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa agttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01001680             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11005:3887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001680
VERSION     KCVT01001680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11005:3887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..245
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79205.1"
                     /translation="CLQFKTFPYSF"
     J_segment       246..283
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           71 a           73 c           71 g           71 t
ORIGIN      
        1 acatggggag acactgtcac catctcttgc cgggcaagtc agggtattag cagttcttta
       61 agttggtttc agcagaaacc agggaaagcc cctaagctcc tcatctatgc tgcatccact
      121 ttggccggtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga cttcactctc
      181 accatcagca gcctgcagcc tgaagatttt gcaacttatt actgtctaca gtttaaaact
      241 ttcccgtaca gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01001681             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26108:6329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001681
VERSION     KCVT01001681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26108:6329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79206.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          113 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001682             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:4184:17711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001682
VERSION     KCVT01001682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4184:17711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79207.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc ggggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001683             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25755:14336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001683
VERSION     KCVT01001683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25755:14336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79208.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgta acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001684             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6150:14253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001684
VERSION     KCVT01001684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6150:14253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79209.1"
                     /translation="CLQGYSAPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          105 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcttcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa actcctcagc gcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggttat agtgccccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01001685             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9523:6625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001685
VERSION     KCVT01001685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9523:6625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79210.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          119 c          108 g           92 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag tctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001686             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:26957:10345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001686
VERSION     KCVT01001686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:26957:10345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79211.1"
                     /translation="CQQGYYTPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          118 c          111 g           91 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagttcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcgtccctg tctgcatctg taggagacaa agtcaccatc acttgccgag ccagtcaggg
      181 tattagcagc tggttagcct ggtatcagca gaaaccaggg aaagccccta gactcctgat
      241 ctataaggcg tccactttgg caagtggggt cccatcaacc ttcagcggca gtggatctgg
      301 gacggattac actctcacca tcaacaggct gcagcctgaa gattttgcta cttattattg
      361 tcaacagggt tactataccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001687             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15687:4929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001687
VERSION     KCVT01001687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15687:4929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79212.1"
                     /translation="CQQHDNSPPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           93 t
ORIGIN      
        1 acatgggagt cagtctcaga cagggcacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 ttcctccctg tctgcatcta taggcgacag agtcaccatc acttgcagag ccagtcaggg
      181 tattagcgac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aactcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcaggctgaa gatttcgcaa catatttctg
      361 tcaacagcat gataattccc ctcccacttt cggtggaggg actaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001688             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11932:6930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001688
VERSION     KCVT01001688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11932:6930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..444
                     /note="immunoglobulin light chain variable region"
     V_region        105..444
     V_segment       105..407
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79213.1"
                     /translation="CMQSLEFPWTF"
     J_segment       408..444
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          110 t
ORIGIN      
        1 acatgggggg aactgatcac gactcctcag gtcaccttct cacaatgagg ctccctgctc
       61 agctcctggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
      121 agactccact ctccctgccc gtcacccttg gggagccggc ctccatctcc tgtaggtcta
      181 gtcagagcct cttggatgtt gaggatggaa acacctattt ggactggtac ctgcagaagc
      241 caggccagtc tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      301 acaggttcag tggcagtggg tctgacactg atttcacact gaaaatcagt agagtggagg
      361 ctgaggatgt tgggttttat ttctgcatgc aaagtctgga gtttccttgg acgttcggcc
      421 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01001689             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15226:9993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001689
VERSION     KCVT01001689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15226:9993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79214.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001690             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15563:12061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001690
VERSION     KCVT01001690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15563:12061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..329
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79215.1"
                     /translation="CQQHDDSPRTF"
     J_segment       331..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           96 a           99 c           92 g           82 t
ORIGIN      
        1 acatgggggg gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc
       61 agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca
      121 gtcagggtat taataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac
      181 tccttatcta tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg
      241 gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat
      301 atttctgtca acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa
      361 tcaaacgag
//
LOCUS       KCVT01001691             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5708:13310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001691
VERSION     KCVT01001691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5708:13310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79216.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          117 c          112 g           88 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcaggatatt aacaactggt tggcctggta tcaacagaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca ttttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001692             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21906:19086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001692
VERSION     KCVT01001692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21906:19086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79217.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagta ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001693             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:11253:11054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001693
VERSION     KCVT01001693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11253:11054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79218.1"
                     /translation="CQQVYSNPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          113 c          109 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctatag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ctatagtcat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agattgcaaa gtgggactcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaggtt attactgtca
      361 acaggtttat agtaacccgc tcactttcgg cggagggact agggtggaaa tcaaacgag
//
LOCUS       KCVT01001694             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20889:18144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001694
VERSION     KCVT01001694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20889:18144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..446
                     /note="immunoglobulin light chain variable region"
     V_region        125..446
     V_segment       125..408
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79219.1"
                     /translation="CQQGSPFPWTF"
     J_segment       409..446
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>449
                     /gene="IGKC"
BASE COUNT          113 a          116 c          116 g          104 t
ORIGIN      
        1 acatggggag aggctctttc tctgggatgt ggcatgagca aaactgacaa gtcaaggcag
       61 gaagatgttg tctccatcac aactcattgg gtttctgctg ctctgggttc cagcctccaa
      121 gggtgaaatt gtgctgactc agtctccagc ctttcggtct gtgactctaa aggagaaagt
      181 caccatcacc tgccaggcca gtcagagcat tggtaatagc ttacactggt accagcagaa
      241 accggatcag tctccaaagc tcctcatcaa atatgcttcc cagtccatct caggggtccc
      301 ctcaaggttc agtggcagtg gatctgggac agatttcacc ctcaccatca atagcctgga
      361 agctgaagat gctgcgacgt attactgtca gcagggaagt cctttcccgt ggacgttcgg
      421 ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001695             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:11674:15788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001695
VERSION     KCVT01001695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11674:15788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79220.1"
                     /translation="CQEYNRLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aggctcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaggagta taatcgttta cctcggacgt tcggccaagg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01001696             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16685:7818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001696
VERSION     KCVT01001696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16685:7818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..327
                     /note="immunoglobulin light chain variable region"
     V_region        10..327
     V_segment       10..288
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79221.1"
                     /translation="CQQGYSYHPTF"
     J_segment       297..327
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>334
                     /gene="IGKC"
BASE COUNT           79 a           91 c           83 g           81 t
ORIGIN      
        1 acatggggtg acttccttat gacgcagtct ccttcctccc tgtccgcatc tgtaggagac
       61 acagtcacca tcacttgcca ggcgagtcaa gccattggca ctaatttaaa ttggtatcag
      121 cagagaccag gaaaagcccc taaactcctg atctataggg cttccggttt gcagagtggg
      181 actccctctc ggttcagcgg cagtggatct gggacggatt tcagtctcac catcagcagc
      241 ctgcagcctg aagattttgc cacttattac tgtcaacagg gttatagtta ccatcccact
      301 ttcggcggag ggaccaaggt ggagatccaa cgag
//
LOCUS       KCVT01001697             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11196:16166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001697
VERSION     KCVT01001697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11196:16166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79222.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001698             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:28819:13391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001698
VERSION     KCVT01001698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:28819:13391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79223.1"
                     /translation="CQKYSSSPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           97 a          127 c          108 g           93 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac ctggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccagactcct
      241 catctatggt gcttccagca gggccactgc catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagaag tatagtagtt ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01001699             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12097:19093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001699
VERSION     KCVT01001699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12097:19093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79224.1"
                     /translation="CMQYRHIPFTF"
     J_segment       282..319
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           75 a           84 c           81 g           82 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      241 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      301 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01001700             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16804:4137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001700
VERSION     KCVT01001700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16804:4137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79225.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          109 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaccgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtat gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct ctagagtttc cttggacgtt cggccagggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001701             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13171:15428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001701
VERSION     KCVT01001701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13171:15428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79226.1"
                     /translation="CLQGYNIPYNF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          110 c          112 g           98 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag ttgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgattattta agttggtatc agcagaaacc aggaaaagct cctaagcgcc
      241 tgatctatgc tgtgtccagt ttggaaggtg gggtcccatc aagattcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcgacttatt
      361 actgtctaca gggttataat atcccgtaca attttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001702             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17140:12252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001702
VERSION     KCVT01001702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17140:12252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79227.1"
                     /translation="CQQGYTPPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          119 c          114 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcgtc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattagca gctggttagc ctggtatcag caggaaccag ggaaagcccc taaactcctg
      241 atctataagg cgtccagttt ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcaacagc ctgcagcctg aagattttac aacttattat
      361 tgtcaacagg gttacactcc ccctctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001703             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13032:9192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001703
VERSION     KCVT01001703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13032:9192"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79228.1"
                     /translation="CQQYNSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          110 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaattg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 aggacattag gaattattta gcgtggtatc agcagaaacc agggaaagcc ccgaaggcct
      241 tgatctatta cacatccatt ttggaaaatg gggtcccatc aaggttcagc ggcggtggat
      301 ctgggacaga attcagtctc accatcagca gcctgcaggc tgaggatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001704             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22615:7683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001704
VERSION     KCVT01001704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22615:7683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    173..327
                     /note="immunoglobulin light chain variable region"
     V_region        173..327
     V_segment       173..286
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79229.1"
                     /translation="CQQSYRYPLTF"
     J_segment       292..327
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>332
                     /gene="IGKC"
BASE COUNT           72 a           94 c           92 g           74 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca ggagtggggt
      181 cccatcaagg ttcagcggca gtggatctgg gacagatttc actctcgcca tcagcagcct
      241 gcagcctgaa gatgctgcaa cttattactg tcagcagagt tatcgttatc cgctcacttt
      301 cggtggaggg acccaggtgg aaatcaatcg ag
//
LOCUS       KCVT01001705             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:8771:11566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001705
VERSION     KCVT01001705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8771:11566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79230.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          116 c          101 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctaca gcctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01001706             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:24290:14109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001706
VERSION     KCVT01001706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24290:14109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79231.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          116 g          111 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001707             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16463:18352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001707
VERSION     KCVT01001707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16463:18352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..439
                     /note="immunoglobulin light chain variable region"
     V_region        104..439
     V_segment       104..401
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79232.1"
                     /translation="CMQDIQLPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          124 c          121 g          105 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctggggc tgctggtgct ctggctccct gggaccagtg ggaatattgt gatgactcag
      121 actccactct ccctgcccgt cacccctgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctcc tgcatagtaa tggatacacc tatttgtttt ggtacctgca gaagccaggc
      241 cagtctccac aactcctgat ctacttgggt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg tactgatttc acactgaaaa tcagccgggt ggaggctgaa
      361 gatgttgggg tttattactg catgcaagat atacagcttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001708             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9418:13243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001708
VERSION     KCVT01001708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9418:13243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    68..404
                     /note="immunoglobulin light chain variable region"
     V_region        68..404
     V_segment       68..366
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79233.1"
                     /translation="CLQDIQLPLTF"
     J_segment       367..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           81 a          112 c          115 g           99 t
ORIGIN      
        1 acatgggatg aggctccctg ctcagctcct ggggctgctg gtgctctggc tccctgggac
       61 cagtggggat attatgatga ctcagactcc actctccctg tccgtcaccc ctggagagcc
      121 ggcctccatc tcctgcaggt ctagtcagag cctcctgcat aggaatgggt acacctattt
      181 gttttggtac ctgcagaagc caggccagtc tccacagctc ctgatctatt tcggttccaa
      241 ccgggcctct ggagtcccag acaggttcag tgccagtggg tcaggcactg atttcacact
      301 gaaaatcagc cgggtggagg ctgaggatgt tggggtttat tactgcttgc aagatataca
      361 acttccgctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001709             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9847:15584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001709
VERSION     KCVT01001709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9847:15584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79234.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          117 c          104 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac acatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01001710             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15217:12397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001710
VERSION     KCVT01001710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15217:12397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79235.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          108 a          119 c          110 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccagc tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagtca
      181 ggatattaat acctggttgg cctggtatca acagaaacca ggaaaagccc ctaaactcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcggtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 gcgag
//
LOCUS       KCVT01001711             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14221:19001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001711
VERSION     KCVT01001711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14221:19001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..441
                     /note="immunoglobulin light chain variable region"
     V_region        120..441
     V_segment       120..399
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79236.1"
                     /translation="CQQYNSDWRTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          111 a          119 c          119 g           95 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggga gtcagaccca gtcaggacac agcatggaca
       61 tgagggtccc cgctcagctc ctaggactcc tgctgctctg tctcccaggt gccaaatgtg
      121 acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac agagtcacca
      181 tcacttgtcg ggcgagtcag ggcattcgca gttatttagc gtggtatcag cagaaaccag
      241 ggaaagcccc gaagcccttg atctattacg cgtccacttt ggaaagtggg gtcccatcaa
      301 ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc ctgcagcctg
      361 aagattttgc aacttattac tgtcaacagt ataacagtga ctggcgcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001712             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15071:19935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001712
VERSION     KCVT01001712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15071:19935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    52..391
                     /note="immunoglobulin light chain variable region"
     V_region        52..391
     V_segment       52..353
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79237.1"
                     /translation="CVQALEFPWTF"
     J_segment       354..391
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT           87 a          101 c          111 g           95 t
ORIGIN      
        1 acatgggagc tcctgggact gctaatgctc tggctccctg gatccaatgg ggacattgtg
       61 atgacccaga ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc
      121 aggtctagtc agagcctctt ggatagtgag gatggaaaca cctatttgga ttggtacctg
      181 cagaagccag gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga
      241 gtcccagaca ggttcagtgg cagtgggtct gacactgatt tcacactgaa aatcagcaga
      301 gtggaggctg aggatgttgg ggtttattac tgcgttcaag ctctagagtt tccgtggact
      361 ttcggccaag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001713             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22423:5414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001713
VERSION     KCVT01001713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22423:5414"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79238.1"
                     /translation="CQQGYSYPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          119 c          108 g           96 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg caggagacac agtcaccatc acttgccagg cgagtcaagg
      181 cattggcaat actttaaatt ggtatcaaca gaaaccgggg aaagccccta cactcctgat
      241 ctatagggca tccggtttgc aaagtgggac tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagttatc cgtacagttt tggccagggg accaaactgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001714             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13198:10648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001714
VERSION     KCVT01001714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13198:10648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79239.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          121 c          117 g           86 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccag cagaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001715             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5545:11022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001715
VERSION     KCVT01001715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5545:11022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..430
                     /note="immunoglobulin light chain variable region"
     V_region        91..430
     V_segment       91..393
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79240.1"
                     /translation="CMQALEFPLTF"
     J_segment       394..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           94 a          116 c          122 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct cctgggactg
       61 ctaatgctct ggctccctgg atccagcggg gacattgtga tgacccagac tccactctcc
      121 ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca gagcctcttg
      181 gatggtgagg atggaaacac gtacttggaa tggtatttgc agaagccagg ccagtctcca
      241 caactcttga tttatgaggt ttccaagcgg gcctctggag tcccagacag gttcagtggc
      301 agtgggtcag gcactgattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttatcact gcatgcaagc tctagagttt cctctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01001716             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20760:5161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001716
VERSION     KCVT01001716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20760:5161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79241.1"
                     /translation="CQQDYDWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          121 c          114 g           89 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagatacagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcacctt agtatggtac caccagaaac ctgggcaggc tcccacgctc
      241 ctcgtctatg gtacatccat cagggccacc ggcatcccag acaggttcag tgccagtggg
      301 tctggaacag agtttactct caccatcagc agcctggaga ctgaagatat tggagtttat
      361 tattgtcagc aggattatga ttggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01001717             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17335:15451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001717
VERSION     KCVT01001717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17335:15451"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79242.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001718             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16737:14380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001718
VERSION     KCVT01001718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16737:14380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79243.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattactgt atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001719             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19709:12725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001719
VERSION     KCVT01001719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19709:12725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..439
                     /note="immunoglobulin light chain variable region"
     V_region        99..439
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79244.1"
                     /translation="CMQAREFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          126 c          116 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt tttattactg catgcaagct cgagagtttc cattcacttt cggccccggg
      421 accaaactgg acatcaaacg ag
//
LOCUS       KCVT01001720             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19806:9142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001720
VERSION     KCVT01001720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19806:9142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79245.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatcaggttt ccaaccgggc ctctggggtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggaat ttatttctgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001721             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24610:6716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001721
VERSION     KCVT01001721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24610:6716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79246.1"
                     /translation="CMEALEFPYSF"
     J_segment       401..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          116 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cattggggac atcgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat gttgaggatg gaaacaccta tttggaatgg cacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tggaagctct agaatttccc tacagttttg gccaggggac
      421 caaactggag atcaagcgag
//
LOCUS       KCVT01001722             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9699:14630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001722
VERSION     KCVT01001722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9699:14630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..297
                     /note="immunoglobulin light chain variable region"
     V_region        9..297
     V_segment       9..259
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79247.1"
                     /translation="CQHSYGTPFTF"
     J_segment       262..297
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           82 a           71 c           75 g           72 t
ORIGIN      
        1 acatgggatc tgcatctgta ggagacagag tcaccatcac ttgtaggaca agtcagaacg
       61 ttaacaacta tttacattgg tatcagcaga aaccagggaa agcccctagg ctcctgatct
      121 atgctgcgtc caatttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      181 cagatttcac tttcaccatc accagcctgc aacctgaaga tgttgcaact tattactgtc
      241 agcatagtta tggtaccccg ttcactttcg gtggagggac cgaggtggag atcaaacgag
//
LOCUS       KCVT01001723             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16413:15411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001723
VERSION     KCVT01001723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16413:15411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79248.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          110 a          116 c          108 g           86 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcaggata
      181 ttaacacctg gttggcctgg tatcaacaga agccagggaa agcccctaag gtcctgatct
      241 ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc aacagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001724             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17820:5811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001724
VERSION     KCVT01001724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17820:5811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79249.1"
                     /translation="CQQYNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagt ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001725             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12587:16169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001725
VERSION     KCVT01001725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12587:16169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79250.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgtgat gacccagact
      121 ccactctccc tggccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 atcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001726             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24266:3554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001726
VERSION     KCVT01001726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24266:3554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79251.1"
                     /translation="CLQYKSYPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           97 a          115 c          107 g           99 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgcccga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg cttctgtagg agacactgtc accatcactt gccgggcaag tcagggtctt
      181 agtagctctt tacattggtt tcagcagaaa ccagggaaag cccctaggct cctgatctat
      241 gctgcatcca ctttggcagg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gagttcactc tcaccatcag cagcctgcag cctgaagata ttggtactta ttactgtcta
      361 cagtataaaa gttacccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01001727             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11456:15168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001727
VERSION     KCVT01001727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11456:15168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..358
                     /note="immunoglobulin light chain variable region"
     V_region        45..358
     V_segment       45..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <298..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79252.1"
                     /translation="CMQALEFPWTF"
     J_segment       322..358
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>361
                     /gene="IGKC"
BASE COUNT           83 a           91 c          104 g           83 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccgtcacc
       61 ctgggagagc cggcctccat gtcctgcagg tctagtcaga gcctcttgga tagtgaggat
      121 ggaaacacct atttggaatg gcacctgcag aggccaggcc agtctccaca gctcttgatt
      181 tatgaggttt cctatcgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac
      241 actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc
      301 atgcaagctc tagagtttcc ttggacgttc ggccaaggga ccaaggtgga aatcaaacga
      361 g
//
LOCUS       KCVT01001728             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8097:7487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001728
VERSION     KCVT01001728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8097:7487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79253.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001729             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13294:13638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001729
VERSION     KCVT01001729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13294:13638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79254.1"
                     /translation="CMQGLEFPPTF"
     J_segment       406..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          124 c          121 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggc gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtggtg atggaaacac ctatttggaa tggttcctcc agaggccagg
      241 ccagtctcca cacctcttga tttatggggc ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagg tctagagttt cctccgacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001730             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13978:5764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001730
VERSION     KCVT01001730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13978:5764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79255.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          110 c          107 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctccttct gtcggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 tcattaggag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agactttgga acttattact
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001731             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10453:15224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001731
VERSION     KCVT01001731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10453:15224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79256.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          121 c          123 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccagccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa gatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001732             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7950:13817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001732
VERSION     KCVT01001732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7950:13817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79257.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          115 c          105 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatttct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt attactgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001733             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20708:23322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001733
VERSION     KCVT01001733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20708:23322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79258.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          127 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg ccggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001734             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21382:17575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001734
VERSION     KCVT01001734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21382:17575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..415
                     /note="immunoglobulin light chain variable region"
     V_region        96..415
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79259.1"
                     /translation="CLQFKSYPNSF"
     J_segment       382..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>420
                     /gene="IGKC"
BASE COUNT          100 a          115 c          107 g           98 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatcac ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctaag ctcctcatct
      241 atgctgcatc cactttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtttaa aagttacccg aacagttttg gccaggggac caaagtggag atcaagcgag
//
LOCUS       KCVT01001735             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4854:7287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001735
VERSION     KCVT01001735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4854:7287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79260.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          116 g          103 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gtacctccag aagccatgcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggac ttattactgc atccaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001736             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:6062:4983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001736
VERSION     KCVT01001736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:6062:4983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79261.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          111 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acgttaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001737             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18329:5611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001737
VERSION     KCVT01001737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18329:5611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79262.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc ggggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001738             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22449:5212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001738
VERSION     KCVT01001738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22449:5212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79263.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          119 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggtgagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctt tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001739             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19592:6568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001739
VERSION     KCVT01001739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19592:6568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79264.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          123 c          113 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agaatgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaggctcc
      241 ttgtccatag tgcattcttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001740             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7698:9735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001740
VERSION     KCVT01001740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7698:9735"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79265.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaat agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001741             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19824:16408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001741
VERSION     KCVT01001741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19824:16408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79266.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001742             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16516:9626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001742
VERSION     KCVT01001742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16516:9626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79267.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001743             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7993:10519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001743
VERSION     KCVT01001743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7993:10519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79268.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggta gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001744             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:3995:7021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001744
VERSION     KCVT01001744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3995:7021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79269.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaaa ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct tggagagccg gccaccatct cctgcaggtc tagtcagagc
      181 ctcttggcta gtgaggatgg aaacacctat ttggagtggt tcctgcagaa gccaggccag
      241 tctccacacc tcttgattta tgacgtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01001745             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18894:10824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001745
VERSION     KCVT01001745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18894:10824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79270.1"
                     /translation="CQQYNSNPFTF"
     J_segment       378..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          110 a          114 c          100 g           94 t
ORIGIN      
        1 acatggggga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccga gtctccatcc
      121 tccctgtctg catctgtagg agacagagta accatcactt gtcgggcgag tcaggacata
      181 agaagttatt tagcgtggta tcagcagaaa ccaggcaaag ccccgaagcc cttgatctat
      241 tacgcatccg ttttggaaag tggggtccca tcaaggttca gtggcagtgg atctgggaca
      301 aaattcactc tcaccatcag cagtctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataaca gtaacccatt cactttcggc cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01001746             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:23645:11511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001746
VERSION     KCVT01001746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23645:11511"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79271.1"
                     /translation="CQQVYGNPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          120 c          104 g          101 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccagatg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg acaagtcaga
      181 acatttatag ttatttagcg tggtatcagc agaaaccagg gaaagcccct gagctcctga
      241 tctatgctgt atccagattg caaagtggga ttccctctcg cttcagcggc ggtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattctgca acttactact
      361 gtcaacaggt ttatggcaac cccttcacct tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001747             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18980:19258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001747
VERSION     KCVT01001747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18980:19258"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79272.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          118 c          106 g           87 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacgt ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgtg ggagacagag tcaccatcac ttgcacagcc agtcacgata
      181 ttaataactg gttggcctgg tatcaacaga aaccaggaaa aacccctaaa ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcgaggtt cggtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001748             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16067:7860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001748
VERSION     KCVT01001748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16067:7860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79273.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catacgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001749             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18750:16611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001749
VERSION     KCVT01001749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18750:16611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79274.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          118 c          105 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagtctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001750             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:4409:11056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001750
VERSION     KCVT01001750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4409:11056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79275.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactaatttc acactgagaa tcagtagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001751             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:26938:9633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001751
VERSION     KCVT01001751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26938:9633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79276.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggtt cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001752             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13478:14004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001752
VERSION     KCVT01001752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13478:14004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..425
                     /note="immunoglobulin light chain variable region"
     V_region        95..425
     V_segment       95..388
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <368..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79277.1"
                     /translation="CLQSRNSYSF"
     J_segment       389..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          112 c          110 g          105 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggcttcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cgatttcttt ggaataaacc tcattcactg gtatcagcag aaaccgggac aacctcctaa
      241 actcctgatt taccaagaat tcaataaaga cactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgacg atgctgcaca
      361 ttattattgt ctgcagagta ggaattctta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01001753             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7576:12728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001753
VERSION     KCVT01001753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7576:12728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..364
                     /note="immunoglobulin light chain variable region"
     V_region        43..364
     V_segment       43..326
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79278.1"
                     /translation="CQQYNSLPYSF"
     J_segment       327..364
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           93 a           91 c           92 g           91 t
ORIGIN      
        1 acatgggggc tcctgctgct ctggctccca ggtgccagat gtgacattga gatgacccag
       61 tctccatcct ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt
      121 cagggcgtta acgtttattt aaattggtat caacagaaac cggggaaagc ccctaagccc
      181 ctgatctttt atgcaaaccg tttggaacgt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc agcctgcaac ctgaagattt tgcaagttat
      301 tattgtcaac agtataatag tttaccgtac agttttggcc aggggaccaa agtggagatc
      361 aaacgag
//
LOCUS       KCVT01001754             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13583:5416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001754
VERSION     KCVT01001754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13583:5416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..406
                     /note="immunoglobulin light chain variable region"
     V_region        85..406
     V_segment       85..363
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <346..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79279.1"
                     /translation="CQQGYRYPYSF"
     J_segment       369..406
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>409
                     /gene="IGKC"
BASE COUNT           99 a          114 c          102 g           94 t
ORIGIN      
        1 acatggggag gacacagcat ggacatgagg gtccccgctc agctccttgg gctcctgctg
       61 ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc ctccctgtcc
      121 gcatctgtgg gagacacagt cacgatcact tgccaggcga gtcaagacat tgacattaat
      181 ttaagttact atcaacagaa accaggggaa gcccctaaac tcctgatcta tagggcatcc
      241 cgtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac ggatttcact
      301 ctcaccatca ccagcctgca gcctgaagat tttgccactt attactgtca acagggttat
      361 cgttacccgt acagttttgg ccaggggacc aaagtagaga tcaaacgag
//
LOCUS       KCVT01001755             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9331:13794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001755
VERSION     KCVT01001755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9331:13794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79280.1"
                     /translation="CQQDFDWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          128 c          116 g           90 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc
      241 tcccaagctc ctcctctatg gtgcatccac cagggccacc ggcgtcccag acaggttcag
      301 tgtcagtggg tctggaacag aatttactct caccatcacc agcctggagc ctgaagatgt
      361 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01001756             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15441:17029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001756
VERSION     KCVT01001756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15441:17029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79281.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c          107 g           90 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagtcaggg
      181 tattaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta aactccttat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcggtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catatttctg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001757             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:25448:6640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001757
VERSION     KCVT01001757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25448:6640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..364
                     /note="immunoglobulin light chain variable region"
     V_region        41..364
     V_segment       41..327
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79282.1"
                     /translation="CMQTLEFPLTF"
     J_segment       328..364
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           82 a           97 c          100 g           88 t
ORIGIN      
        1 atggggtgat cacgactcct caggtcacct tctcacaatg aggctccact ctccctgccc
       61 gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct cttggatggt
      121 gaggatggaa acacctattt ggattggtac ctgcagaagc caggccagtc tccacagctc
      181 ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag tggcagtggg
      241 tcagacactg atttcacact gaaaatcacc agagtggagg ctgaggatgt tggggtttat
      301 tactgcatgc aaactctaga gtttcctctc actttcggcg gagggaccaa ggtggagatc
      361 aaacgag
//
LOCUS       KCVT01001758             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20412:10562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001758
VERSION     KCVT01001758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20412:10562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79283.1"
                     /translation="CQHSYDTPYTF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          116 c          106 g           96 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagtg tcaccatcac ttgcagggca agtgcgaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agtccctgag ctcctgatct
      241 atgctgcatc gtctttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac cctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtta tgataccccc tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01001759             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12307:12701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001759
VERSION     KCVT01001759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12307:12701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79284.1"
                     /translation="CMQALEFPWTF"
     J_segment       407..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gtaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gattggtacc tgcagaagcc
      241 aggccagtct ccacacctct tgatttatga agtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagag tttccttgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001760             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24115:5703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001760
VERSION     KCVT01001760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24115:5703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..315
                     /note="immunoglobulin light chain variable region"
     V_region        116..315
     V_segment       116..277
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <255..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79285.1"
                     /translation="CMQALEFPFTF"
     J_segment       278..315
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>318
                     /gene="IGKC"
BASE COUNT           70 a           84 c           85 g           79 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctcatgctc tggctccctg gatccagtgg ggacattgtg atgacccagt
      121 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      181 gtggcagtgg gtcagacact gatttcacac tgaaaatcag cagagtggag gctgaggatg
      241 ttggggttta ttactgtatg caagctctag agtttccatt caccttcggc cccgggacca
      301 aagtggatat caaacgag
//
LOCUS       KCVT01001761             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23392:7819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001761
VERSION     KCVT01001761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23392:7819"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79286.1"
                     /translation="CMQALEFPYTF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagagt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 accctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctcctc aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcaacagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttacacttt tggccagggg
      421 accacagtgg agatcaaacg ag
//
LOCUS       KCVT01001762             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11915:7740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001762
VERSION     KCVT01001762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11915:7740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79287.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agactttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001763             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19284:13482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001763
VERSION     KCVT01001763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19284:13482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79288.1"
                     /translation="CQQGNSIPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          114 c          106 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatt acttgccggg caagtcaggg
      181 cattagcaat tatttaaatt ggtatcagca gaaaccgggg aaagccccaa aggtcctgat
      241 ctattatgca gacagtttgt caagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagggt aacagtattc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01001764             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12690:18564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001764
VERSION     KCVT01001764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12690:18564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..275
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79289.1"
                     /translation="CQQYDSFPLTF"
     J_segment       278..313
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           78 a           82 c           77 g           79 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgct tctgtgggag acagagtcac catcacttgc
       61 cgggctagtc aggacattag taatttttta aattggtatc agcagaaacc ggggaaagcc
      121 cctaagctcc tgatctatta tggaaaccgt ttgggaagcg gggtcccatc aaggttcagc
      181 ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc tgaggatttt
      241 gcgacttatc attgtcagca gtatgatagt ttccccctca ctttcggccc cgggaccaaa
      301 ctggatatca aacgag
//
LOCUS       KCVT01001765             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16044:8731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001765
VERSION     KCVT01001765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16044:8731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79290.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg actcgctcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01001766             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:27257:7165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001766
VERSION     KCVT01001766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27257:7165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..485
                     /note="immunoglobulin light chain variable region"
     V_region        104..485
     V_segment       104..447
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <425..>457
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79291.1"
                     /translation="CMQALEFPYSF"
     J_segment       448..485
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        486..>488
                     /gene="IGKC"
BASE COUNT          111 a          142 c          127 g          108 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctattgc tctggctccc tggatccact ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc atggacagca aggacaacac ctacagcctg agcagcaccc tgacgctgag
      241 cagcacagac taccagagtc acaatgtcta tgcctgcgaa gtcacccagt ctccacatct
      301 cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg
      361 gtcagacacg gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta
      421 ttactgcatg caagctctag agtttccgta cagttttggc caggggacca gagtggagat
      481 caaacgag
//
LOCUS       KCVT01001767             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15509:6324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001767
VERSION     KCVT01001767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15509:6324"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79292.1"
                     /translation="CIQSLEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          110 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc ttctcctgta ggtctagtca
      181 cagcctcttg gatagtgagg atggaaatat ccatttggat tggtatctgc agaagccagg
      241 ccagtctcca cacctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gtttagtggc agtgggtcag acactgattt cacactgaaa atcagcaggg tggaggctga
      361 ggatgttggg gtttactact gcatacagtc tctagagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001768             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:5918:10169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001768
VERSION     KCVT01001768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:5918:10169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..247
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79293.1"
                     /translation="CQQNSNWPLTF"
     J_segment       248..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           70 a           76 c           84 g           57 t
ORIGIN      
        1 acatggggga gaaagagcca ccctctcctg cagggccagt cagagtgtca gcagcagctt
       61 agcctggtac cagcagaaac ctgggcaggc tcccaggctc ctcatctatg gtgcatccaa
      121 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcactct
      181 caccatcagc agcctggagc ctgaagatgt tgcagtttat tattgtcagc agaatagtaa
      241 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001769             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8089:13969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001769
VERSION     KCVT01001769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8089:13969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79294.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgtgat gacccagact
      121 ccgctctccc tgcccgtcat ccttggagag ccggcctccc tatcctgcac gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001770             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16519:13103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001770
VERSION     KCVT01001770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16519:13103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79295.1"
                     /translation="CQRYSYSTWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagcttg gtttggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtatatt
      361 actgtcagag gtatagttac tccacgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001771             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:10136:1918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001771
VERSION     KCVT01001771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10136:1918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79296.1"
                     /translation="CQQGYSYPCSF"
     J_segment       382..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          116 c          108 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaag tcctgatcta
      241 tagggcatcc ggtttgcaaa gtgggcttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcaacctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttacccgt gcagttttgg ccaggggacc acagtggaca tcaaacgag
//
LOCUS       KCVT01001772             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8501:5645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001772
VERSION     KCVT01001772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8501:5645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79297.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgtttgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01001773             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22825:22629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001773
VERSION     KCVT01001773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22825:22629"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..307
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79298.1"
                     /translation="CQQGNSNPLTF"
     J_segment       308..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           93 a           86 c           85 g           83 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgtcccag tttccatcct ccctgtctgc
       61 atctgtagga gacagagtca ccatcacttg ccgggcaagt caggccatta gcagttattt
      121 aaattggtat cagcagaaac cggggaaagc ccctaaactc ctgatatact atggaaaaag
      181 tttggtaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcacc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agggtaatag
      301 taatcctctc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001774             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19853:14506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001774
VERSION     KCVT01001774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19853:14506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79299.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001775             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7545:11042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001775
VERSION     KCVT01001775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7545:11042"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79300.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          114 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001776             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20692:12035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001776
VERSION     KCVT01001776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20692:12035"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79301.1"
                     /translation="CQQYNSDPRTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          118 c          109 g           92 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcac tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttatttctgt
      361 caacagtata acagtgaccc gcgcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01001777             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20559:1972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001777
VERSION     KCVT01001777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20559:1972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79302.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagtc
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc acaaaccagg
      241 ccagtctcca gagctcttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg ctttattact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gaggtcaaac gag
//
LOCUS       KCVT01001778             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15476:9435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001778
VERSION     KCVT01001778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15476:9435"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..433
                     /note="immunoglobulin light chain variable region"
     V_region        94..433
     V_segment       94..395
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79303.1"
                     /translation="CMQALEFPLTF"
     J_segment       396..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          102 t
ORIGIN      
        1 acatggggac gactcctcag gtcccttctc acaatgaggc tccctgctca gctcctggga
       61 ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca gactccactc
      121 tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtcaag tcagagcctc
      181 ctggatagtg aggatggaaa cacctatttg cactggtact tgaagaagcc aggccagtct
      241 ccacaggtct taatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt
      301 ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt
      361 ggggtttatt actgcatgca agctctagag tttccgctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01001779             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:4884:8687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001779
VERSION     KCVT01001779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4884:8687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79304.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          108 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgggg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa attaacagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001780             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15009:20095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001780
VERSION     KCVT01001780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15009:20095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79305.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           95 a          128 c          110 g           93 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01001781             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18947:4746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001781
VERSION     KCVT01001781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18947:4746"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79306.1"
                     /translation="CLQGYITPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          112 c          110 g           98 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgactt ccagatgacc cagtctccat
      121 cttccctgtc tgcatcggta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcgattt tttaagttgg tatcagcaga aaccaggaaa acctcctaag cgcctgattt
      241 atgctgcatc cagtttgcaa agtggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcggct tattactgtc
      361 tacagggtta tattaccccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01001782             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15801:14159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001782
VERSION     KCVT01001782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15801:14159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79307.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccag agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggc tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001783             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11136:9773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001783
VERSION     KCVT01001783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11136:9773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..340
                     /note="immunoglobulin light chain variable region"
     V_region        19..340
     V_segment       19..301
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>312
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79308.1"
                     /translation="CQQYDSDLFTF"
     J_segment       305..340
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        341..>343
                     /gene="IGKC"
BASE COUNT           87 a           86 c           90 g           80 t
ORIGIN      
        1 acatggggtg ccaaatgtga catccagatg acccagtctc catcctccct gtctgcattt
       61 gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg gcattcgcag ttatttagcg
      121 tggtatcagc agaaaccagg gaaagccccg aagcccttga tctattacgc gtccactttg
      181 gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc
      241 atcagcagcc tgcagcctga agattttgca acttattact gtcaacagta tgacagtgac
      301 ctgttcactt tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01001784             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21860:6014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001784
VERSION     KCVT01001784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21860:6014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79309.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga aggccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01001785             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20118:13255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001785
VERSION     KCVT01001785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20118:13255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79310.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          108 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcttccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaggccctga
      241 tctattatgc aaaccggttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaatctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagta gagatcaaac
      421 gag
//
LOCUS       KCVT01001786             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:12035:3780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001786
VERSION     KCVT01001786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12035:3780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79311.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacacagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagtttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcaacag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001787             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20763:17234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001787
VERSION     KCVT01001787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20763:17234"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..443
                     /note="immunoglobulin light chain variable region"
     V_region        123..443
     V_segment       123..406
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79312.1"
                     /translation="CLQYNSGPWTF"
     J_segment       407..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>447
                     /gene="IGKC"
BASE COUNT          112 a          117 c          116 g          102 t
ORIGIN      
        1 acatggggga ggttggttac acttcatgta gaagttagaa ccactcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctggggc tccttctgct ctggctccca ggtgccagat
      121 gtgacatcca gatgacccag tctccatctt ccctgtctgc atctgaagga gacagagtca
      181 ccatctcttg cagggcaagt caggccatta gtacttattt aaaatgctat caacagaaac
      241 caggaaaagc tcctcagcgc ctgatctatg ctgcacccag tttggaaagt ggggtcccat
      301 taaggttcag tggcagtgga tctgggacag atctcactct caccatcagc agcctgcagc
      361 ctgaagattg tgcaacttat tcctgtctac agtataacag tggcccgtgg acgttcggcc
      421 gagggaccaa ggtggaaatc aaaggag
//
LOCUS       KCVT01001788             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15526:18157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001788
VERSION     KCVT01001788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15526:18157"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..373
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79313.1"
                     /translation="CLQGDTAPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          115 c          115 g           95 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatct tccctgtctg catcggcagg agacagagtc accatcactt gccgggcaag
      181 tcagggcatt aacgattatt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg
      241 cctgatttat gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcagctta
      361 ttactgtcta cagggtgata ctgccccgtt cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01001789             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:10729:5216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001789
VERSION     KCVT01001789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10729:5216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..433
                     /note="immunoglobulin light chain variable region"
     V_region        98..433
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79314.1"
                     /translation="CMQALEFPRTF"
     J_segment       402..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>440
                     /gene="IGKC"
BASE COUNT           94 a          125 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgtatc cagtggtgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc ccctgcaggt ctagtcagag
      181 tctcttggat agtgcggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt ggctcagaca ctgatttcac actgaaaatc agcagagtgg aggctgaaga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct cggacgttcg gccaggggac
      421 caaggtggaa atcgaacgag
//
LOCUS       KCVT01001790             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18437:3390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001790
VERSION     KCVT01001790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18437:3390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79315.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac aacatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcgtc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01001791             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11474:11865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001791
VERSION     KCVT01001791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11474:11865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79316.1"
                     /translation="CMQGLEFPITF"
     J_segment       402..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          123 c          117 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat actgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgatgtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagacg ctgatttcac actgagaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcca atcactttcg gccccgggac
      421 caaactggag atcaaacgag
//
LOCUS       KCVT01001792             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22222:7129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001792
VERSION     KCVT01001792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22222:7129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79317.1"
                     /translation="CQHHNTYPHSF"
     J_segment       386..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          121 c          105 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaggcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacacc ataatactta ccctcacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001793             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17101:11362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001793
VERSION     KCVT01001793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17101:11362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79318.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttatttct
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001794             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:17869:11876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001794
VERSION     KCVT01001794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17869:11876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79319.1"
                     /translation="CIQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          121 c          117 g          110 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cttctcctgt aggtctagtc
      181 acagcctctt ggatagtgag gatggaaata tccatttgga ttggtatctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggtttagtgg cagtgggtca gacactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttactac tgcatacaat ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggacatcaaa cgag
//
LOCUS       KCVT01001795             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8835:17452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001795
VERSION     KCVT01001795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8835:17452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79320.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          125 c          112 g           87 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccacttgc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtctatttt
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001796             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16289:7436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001796
VERSION     KCVT01001796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16289:7436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79321.1"
                     /translation="CQQYNSLPLTF"
     J_segment       377..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          108 a          109 c          104 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc cccgccagat gtgacattca gatgacccag tctccatcct
      121 ccctgtctgc atctgtagga gacacagtca ccatcacttg ccgggcaagt caggacatta
      181 gcagatattt aaattggtat cagcagaaac cggggaaagc ccctaagttc ctaatctatt
      241 atgtaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggagag
      301 aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat tattgtcaac
      361 agtataatag tttaccgctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001797             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16367:17508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001797
VERSION     KCVT01001797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16367:17508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79322.1"
                     /translation="CQQHNSYPLTF"
     J_segment       383..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>422
                     /gene="IGKC"
BASE COUNT          105 a          121 c          106 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattaccaat gatttagcct ggtatcagca gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaactggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagcat aatagttacc cactcacttt cggcggaggg accaaggtgg agatcagacg
      421 ag
//
LOCUS       KCVT01001798             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7395:9815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001798
VERSION     KCVT01001798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7395:9815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..444
                     /note="immunoglobulin light chain variable region"
     V_region        105..444
     V_segment       105..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79323.1"
                     /translation="CMQALDFPWTF"
     J_segment       407..444
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          100 a          121 c          120 g          106 t
ORIGIN      
        1 acatgggggt gactgatcac gactcctcag gtcaccttct cacaatgagg ctccctgctc
       61 agctcctggg actgctaatg ctctggctcc ctggatccat tggggacatt gtgatgaccc
      121 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      181 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggttc ctgcagaagc
      241 caggccagtc tccacaactc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      301 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      361 ctgaggatgt tgggatttat tactgcatgc aagctctaga ctttccgtgg acgttcggcc
      421 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01001799             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12724:22277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001799
VERSION     KCVT01001799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12724:22277"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79324.1"
                     /translation="CQQYDNDPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          116 c          106 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcaacagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac aatgacccgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01001800             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4490:6317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001800
VERSION     KCVT01001800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4490:6317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..303
                     /note="immunoglobulin light chain variable region"
     V_region        12..303
     V_segment       12..266
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79325.1"
                     /translation="CQQDFGWPPTF"
     J_segment       269..303
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>306
                     /gene="IGKC"
BASE COUNT           70 a           83 c           87 g           66 t
ORIGIN      
        1 acatgggcat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
       61 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      121 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      181 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      241 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      301 aacgag
//
LOCUS       KCVT01001801             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9046:7346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001801
VERSION     KCVT01001801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9046:7346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79326.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          123 c          114 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 gctcttggat agtgaggatg aaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatttctgca tgcaagctct agagtttcca ttcactttcg gccccgggac
      421 caagctggaa atcaaacgag
//
LOCUS       KCVT01001802             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11138:12428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001802
VERSION     KCVT01001802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11138:12428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79327.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g           98 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc ttcctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01001803             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13275:5976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001803
VERSION     KCVT01001803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13275:5976"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79328.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          123 c          109 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccggtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctaca tagtaatgaa tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01001804             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16977:8480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001804
VERSION     KCVT01001804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16977:8480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79329.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001805             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11052:16602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001805
VERSION     KCVT01001805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11052:16602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79330.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          123 c          117 g           85 t
ORIGIN      
        1 acatgggggg gaggaactct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01001806             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16654:5786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001806
VERSION     KCVT01001806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16654:5786"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..440
                     /note="immunoglobulin light chain variable region"
     V_region        122..440
     V_segment       122..405
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79331.1"
                     /translation="CQQYFSSPFTF"
     J_segment       406..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>446
                     /gene="IGKC"
BASE COUNT           98 a          133 c          118 g           97 t
ORIGIN      
        1 acatgggggc ctgggtcaga gctctggaga agagctgctc agttaggacc cagagagaac
       61 catggaaatc ccagctcagc ttctcttcct cctgctactg tggctcccag gtaccaccgg
      121 acaagttata ttgactcagt ctccagccac cctgtctttg tctccagggg aaagagccac
      181 cctctcctgc agggccagtc agagtgttgg cagcagctta gcctggtacc agcagaaacc
      241 tgggcaggcc cccaggctcc tcatctatgg tgcatccagc agggccactg gcatcccaga
      301 caggttcagt ggcagtgggt ctgggacaga gttcactctc accatcagca gcctggagcc
      361 tgaagatttt gcagtgtatt actgtcagca gtattttagc tccccattca ctttcggccc
      421 cgggaccaaa ctggatatca gacgag
//
LOCUS       KCVT01001807             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21038:13405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001807
VERSION     KCVT01001807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21038:13405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79332.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccggacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001808             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10622:10757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001808
VERSION     KCVT01001808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10622:10757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79333.1"
                     /translation="CMQNTEDPTF"
     J_segment       398..428
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>434
                     /gene="IGKC"
BASE COUNT          100 a          119 c          110 g          105 t
ORIGIN      
        1 acatggggat caggactcct cagttcatct tctcacgatg agactccctg ctcagctcct
       61 cgggctgttg atgctctggg tccctgggtc cagtggggat attgtgatga cccagactcc
      121 actctcgctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 ccttctgcat agtaatggaa acacctattt gcattggtac ctgcagaagc caggccagtc
      241 tccacgtctc ctgatctata aagttaccaa tcgggaatct ggggtcccag acaggttcag
      301 tggcagtggg tcaggcacag atttcacact gaaaatcagc agggtggagc ctgaagatgt
      361 tggtgtttat tattgcatgc aaaatacaga agatcccact ttcggccccg ggaccaaact
      421 ggatatcata cgag
//
LOCUS       KCVT01001809             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9778:10944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001809
VERSION     KCVT01001809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9778:10944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79334.1"
                     /translation="CQQYDSDSLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           94 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gactcaggac
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01001810             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13472:15845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001810
VERSION     KCVT01001810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13472:15845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79335.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          120 c          118 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01001811             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10395:6315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001811
VERSION     KCVT01001811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10395:6315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79336.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat tagcagagtg gaggctgagg
      361 atgttggggt tttttactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001812             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15314:8820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001812
VERSION     KCVT01001812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15314:8820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..415
                     /note="immunoglobulin light chain variable region"
     V_region        96..415
     V_segment       96..374
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79337.1"
                     /translation="CQQSYRYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>420
                     /gene="IGKC"
BASE COUNT          105 a          117 c          102 g           96 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgagaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agcccctaaa ctcctcatgt
      241 atcttacatc cactttgcaa aatggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tgctgcaact tattactgtc
      361 agcagagtta tcgttatccg ctcactttcg gtggagggac ccaggtggaa atcaatcgag
//
LOCUS       KCVT01001813             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15893:10935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001813
VERSION     KCVT01001813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15893:10935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..397
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79338.1"
                     /translation="CQQGYTFLYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          104 a          121 c          112 g          101 t
ORIGIN      
        1 acatggggga caccctgtgc aggagtcagt ctcagtcagg acacagcatg gacatgaggg
       61 tccccgctca gctccttggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc
      121 agatgacgca gtctccatcc tccctgtccg catctgtagg agacacagtc accatcactt
      181 gccaggcgag tcaggccatt gccaataatt taaattggta tcagcagaaa ccaggaaaag
      241 cccctaaagt cctgatctat agggcatcca gtttgcaaag tgggattccc tctcggttca
      301 gcggcagtgg gtctgggacg gatttcactc tcaccatcag cagcctgcag cctgaagatt
      361 ttgccactta ttactgtcaa cagggttata ctttcctgta cagttttggc caggggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01001814             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:27548:8684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001814
VERSION     KCVT01001814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27548:8684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79339.1"
                     /translation="CQQHDNAPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          115 g           85 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca gcatcagcaa cctgcagcct gaagatatcg caacatatta
      361 ctgtcagcag catgacaatg ccccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001815             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23225:14058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001815
VERSION     KCVT01001815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23225:14058"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79340.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gtaggtctag tcaaagcctt
      181 gtacacatga ctggaaacac attcttgagt tggtatcacc agaggccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatattggg
      361 gtttatttct gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01001816             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:3847:10344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001816
VERSION     KCVT01001816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3847:10344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79341.1"
                     /translation="CQQGYSYPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          116 c          113 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccctcctccc tgtccgcatc tgtaggagac gcagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca ataatttaaa ttggtttcag cagaaaccag ggaaagcccc taaacgcctg
      241 atctataaga catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta cccgtggacg ttcggccaag gggccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001817             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7248:8617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001817
VERSION     KCVT01001817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7248:8617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79342.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaggccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca atatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001818             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16203:11339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001818
VERSION     KCVT01001818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16203:11339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79343.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggc tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc cgtggacgtt cggccaaggg
      421 accaaggtcc aaatcaaacg ag
//
LOCUS       KCVT01001819             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11832:7751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001819
VERSION     KCVT01001819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11832:7751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79344.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          112 c          108 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa acctggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt attactgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001820             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19814:10186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001820
VERSION     KCVT01001820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19814:10186"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79345.1"
                     /translation="CQHSFRTPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          116 c          112 g           97 t
ORIGIN      
        1 acatgggggg gagtcagtct cagtcaggac acagcatgga catgagggcc tctgctcagc
       61 tcctagggct cctgctgctc tggctcccag gcgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcaa tgtcacttgc agggctagtg
      181 agagcgttag caccaaatta cattggtatc agcagaaacc agggaaagcc cctaagctcc
      241 tgatctttgc tgcgtccact ttgcaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctggaacaga tttcactctc accatcagca gcctgcagcc tgaagatgtc gcaacttttt
      361 actgtcagca tagttttcgt accccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01001821             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18401:19077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001821
VERSION     KCVT01001821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18401:19077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79346.1"
                     /translation="CQQESNWSLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          123 c          120 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatctatga tgcatccagc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 tctgtcagca ggagagtaac tggtctctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001822             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11745:10307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001822
VERSION     KCVT01001822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11745:10307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..431
                     /note="immunoglobulin light chain variable region"
     V_region        92..431
     V_segment       92..393
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79347.1"
                     /translation="CMQALDFPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           95 a          116 c          120 g          103 t
ORIGIN      
        1 acatggggac tcctcaggtc accttctcac aatgaggctc cctgctcagc tcctgggact
       61 gctaatgctc tggctccctg gatctagtgg ggacattgtg atgacccaga ctccactctc
      121 cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc agagcctctt
      181 ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag gccagtctcc
      241 acaactcttg atttatgaag tttccgaccg ggcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 ggtttattac tgcatgcaag ctctggactt tccgtggacg ttcggccaag ggaccaaggt
      421 ggaagtcaaa cgag
//
LOCUS       KCVT01001823             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19774:14192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001823
VERSION     KCVT01001823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19774:14192"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79348.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          116 c          112 g           89 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcaggatatt aacaactggt tggcctggta tcaacagaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca ttttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gattttactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01001824             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16170:6783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001824
VERSION     KCVT01001824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16170:6783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79349.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt ggcagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001825             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13166:8484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001825
VERSION     KCVT01001825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13166:8484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79350.1"
                     /translation="CGQASHLPLTF"
     J_segment       394..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>433
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg ccagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 ctacacagcg atggaaacac atacttgagt tggtatcagc agaagtcagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacaggttt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagc ttcacacctt cctctcactt tcggcggagg gaccaaggtg
      421 gagatcagac gag
//
LOCUS       KCVT01001826             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15068:7615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001826
VERSION     KCVT01001826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15068:7615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79351.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          118 g          108 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggattc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001827             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19147:19758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001827
VERSION     KCVT01001827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19147:19758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79352.1"
                     /translation="CEQYNSLPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          111 a          111 c          102 g           96 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaacattta tttaaattgg tatcaccaga aaccggggaa agcccctaag ctcctgatct
      241 attatacaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcaact tattactgtg
      361 aacaatacaa tagtttaccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01001828             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10792:4521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001828
VERSION     KCVT01001828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10792:4521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79353.1"
                     /translation="CQQHNSYPLTF"
     J_segment       387..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          107 a          121 c          108 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaactg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataatagt tacccactca ctttcggcgg agggaccaag gtggagatca
      421 gacgag
//
LOCUS       KCVT01001829             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20332:7334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001829
VERSION     KCVT01001829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20332:7334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79354.1"
                     /translation="CQHSYETPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          119 c          100 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacata cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgccgcatcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gaaacccctt tcactttcgg ccccgggacc aatctggata tcaaacgag
//
LOCUS       KCVT01001830             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18936:11784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001830
VERSION     KCVT01001830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18936:11784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..433
                     /note="immunoglobulin light chain variable region"
     V_region        96..433
     V_segment       96..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79355.1"
                     /translation="CMQSLDFPLTF"
     J_segment       398..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>438
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          106 t
ORIGIN      
        1 atggggatca cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgttatgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagcc
      181 tcctggatag tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacaca gatttcacac tgaaaatcag cagagtggag actgaggatg
      361 ttggggttta ttactgcatg cagtctctag attttccgct cactttcggt ggagggacca
      421 aggtggagat caatcgag
//
LOCUS       KCVT01001831             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10488:16609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001831
VERSION     KCVT01001831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10488:16609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79356.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          124 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01001832             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24535:14717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001832
VERSION     KCVT01001832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24535:14717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79357.1"
                     /translation="CIQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gtcggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggat tggtacctgc agaggccggg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag ccccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcattcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001833             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:4749:19558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001833
VERSION     KCVT01001833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:4749:19558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79358.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001834             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13209:13988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001834
VERSION     KCVT01001834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13209:13988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79359.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaagc
      421 gag
//
LOCUS       KCVT01001835             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10818:13756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001835
VERSION     KCVT01001835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10818:13756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79360.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggat catgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcatgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tgtggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01001836             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:6649:22523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001836
VERSION     KCVT01001836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:6649:22523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79361.1"
                     /translation="CQQGYGFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          118 c          101 g          101 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cgcgatcact tgcctggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tacggcatcc aatttacatg gtgggattcc ctctcggttc agcggcagta gatctgggac
      301 ggatttcact ctcaccatca acagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat ggttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01001837             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16725:17138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001837
VERSION     KCVT01001837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16725:17138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79362.1"
                     /translation="CQQYSSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          106 c          111 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 aagtagttat ttaaattggt atcaacagag accggggaaa gcccctaagg tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcaggttgca acctgaggat tttgcagttt attactgtca
      361 acagtatagt tctttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001838             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13842:12378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001838
VERSION     KCVT01001838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13842:12378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79363.1"
                     /translation="CQHSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          119 c          108 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agtgtcacca tcgcttgcag ggcaagtgcg
      181 aacgttaaca actatttaca ttggtatcac cagaaaccag ggaaagtccc tgagctcctg
      241 atctatgctg catcgtcttt gcaaagtggg gtcccatcaa ggttcagcgg cagtgggtct
      301 gggacagatt tcaccctcac catcagcagc ctgcagcctg acgatgttgc aacttattac
      361 tgtcagcata gttatgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001839             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19626:11893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001839
VERSION     KCVT01001839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19626:11893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79364.1"
                     /translation="CLQYKSYPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          114 c           98 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 ttattatcaa ttatttaaat tggtttcagc agaaaccagg gaaagcccct aagctcctga
      241 tttatgctgc atccagattg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagttac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001840             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16079:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001840
VERSION     KCVT01001840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16079:7995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79365.1"
                     /translation="CQQYNSLPYSF"
     J_segment       367..404
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT          104 a          103 c          103 g           97 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tcctgctgct
       61 cttgctccca ggtgccagat gtgacattca gatgacccag tctccatctt ccctgtctgc
      121 ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacatta gcagtttttt
      181 aaattggtat cagcagaaac cggggaaagc ccctaaggcc ctgatctatt atgcaaaccg
      241 gttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcaat ctgaagattt tgcaacttat tactgtcaac agtataatag
      361 tttaccgtac agttttggcc aggggaccaa agtagagatc aaacgag
//
LOCUS       KCVT01001841             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:10530:7096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001841
VERSION     KCVT01001841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10530:7096"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79366.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccacagtg gagattaaac gag
//
LOCUS       KCVT01001842             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14928:5617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001842
VERSION     KCVT01001842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14928:5617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79367.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          108 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caccggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct agagtttcct tggacgttcg gccaggggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01001843             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21207:9361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001843
VERSION     KCVT01001843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21207:9361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79368.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          122 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001844             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18413:7170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001844
VERSION     KCVT01001844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18413:7170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79369.1"
                     /translation="CVQAIAFPYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           93 a          120 c          120 g          101 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgtcc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggaaaca cctatttcca ctggtacctg cagaagccag gccagtctcc
      241 gcagcccctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcaag ctatagcgtt tccgtacagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01001845             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19983:15805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001845
VERSION     KCVT01001845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19983:15805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..406
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79370.1"
                     /translation="CQQGSPFPWTF"
     J_segment       407..444
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          112 a          116 c          115 g          104 t
ORIGIN      
        1 acatggggag gctctttctc tgggatgtgg catgagcaaa actgacaagt caaggcagga
       61 agatgttgtc tccatcacaa ctcattgggt ttctgctgct ctgggttcca gcctccaagg
      121 gtgaaattgt gctgactcag tctccagcct ttcggtctgt gactctaaag gagaaagtca
      181 ccatcacctg ccaggccagt cagagcattg gtaatagctt acactggtac cagcagaaac
      241 cggatcagtc tccaaagctc ctcatcaaat atgcttccca gtccatctca ggggtcccct
      301 caaggttcag tggcagtgga tctgggacag atttcaccct caccatcaat agcctggaag
      361 ctgaagatgc tgcgacgtat tactgtcagc agggaagtcc tttcccgtgg acgttcggcc
      421 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01001846             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20091:4961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001846
VERSION     KCVT01001846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20091:4961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79371.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          126 c          112 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagcc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001847             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14327:16114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001847
VERSION     KCVT01001847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14327:16114"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79372.1"
                     /translation="CQQYDSDSLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          122 c          117 g           98 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtatgacagt gattcgctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001848             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20665:5426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001848
VERSION     KCVT01001848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20665:5426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79373.1"
                     /translation="CQQGNSNPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          111 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagttt
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gccattagca gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taaactcctg
      241 atatactatg gaaaaagttt ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcaccagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagg gtaatagtaa tcctctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001849             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17073:16925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001849
VERSION     KCVT01001849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17073:16925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..423
                     /note="immunoglobulin light chain variable region"
     V_region        100..423
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79374.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       393..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>430
                     /gene="IGKC"
BASE COUNT          101 a          115 c          112 g          102 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagtt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcaagtcag
      181 gacattggca attatttagc ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctataagg cgtccagttt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agtttattac
      361 tgtcaacagc gtaatagtta cccgtatatg tgcagttttg gcccggggac caaagtggag
      421 atccgacgag
//
LOCUS       KCVT01001850             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16114:19400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001850
VERSION     KCVT01001850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16114:19400"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79375.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001851             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24964:4864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001851
VERSION     KCVT01001851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24964:4864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..374
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79376.1"
                     /translation="CQQNSNWPLTF"
     J_segment       375..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           98 a          119 c          112 g           85 t
ORIGIN      
        1 acatggggag ttaggaccca gagggaacca tggaagcccc agcacagctt ctcttcctcc
       61 tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct ccagccaccc
      121 tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag agtgtcagca
      181 gcagcttagc ctggtaccag cagaaacctg ggcaggctcc caggctcctc atctttggta
      241 catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct gggacagagt
      301 tcactctcac catcagcagc ctggagcctg aagatgttgc agtttattat tgtcagcaga
      361 atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01001852             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23388:20542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001852
VERSION     KCVT01001852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23388:20542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79377.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          112 a          118 c          103 g           87 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcacgata
      181 ttaacaactg gttggcctgg tatcaacaga aaccagggaa agcccctaag gtcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggttctggga
      301 cagatttcac tctcaccatc aacaacctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacaacatga tgattcccct cggaccttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001853             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18069:13275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001853
VERSION     KCVT01001853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18069:13275"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79378.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          103 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagacg gagtcaccat cacttgccgg ccaagtcagg
      181 acattggcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaaatcctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggactttgca acttattact
      361 gtcaacagta taatagttta ccactcactt tcggccccgg gaccaaactg gatgtcaaac
      421 gag
//
LOCUS       KCVT01001854             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:6607:14056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001854
VERSION     KCVT01001854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6607:14056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..365
                     /note="immunoglobulin light chain variable region"
     V_region        42..365
     V_segment       42..327
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79379.1"
                     /translation="CMQSLEFPLTF"
     J_segment       328..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           85 a           96 c          100 g           87 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccac tctccctgcc
       61 cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagcc tcttggatag
      121 tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt ctccacagct
      181 cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg
      241 gtcagacact gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta
      301 ttactgcatg caatctctag agtttccgct cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01001855             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16890:21304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001855
VERSION     KCVT01001855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16890:21304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79380.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc cgtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001856             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21650:13057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001856
VERSION     KCVT01001856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21650:13057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79381.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          110 g           97 t
ORIGIN      
        1 acaggggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001857             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20858:11023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001857
VERSION     KCVT01001857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20858:11023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..439
                     /note="immunoglobulin light chain variable region"
     V_region        103..439
     V_segment       103..402
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79382.1"
                     /translation="CMQDIQLPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           86 a          125 c          124 g          107 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctggggc tgctggtgct ctggctccct gggaccagtg gggatattgt gctgactcag
      121 actccactct ccctgcccgt cacccctgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctcc tgcatagtaa tggatacacc tatttgtttt ggtacctgca gaggccaggc
      241 cagtctccac aacttctggt ctatttgggt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgcaaa tcagccgggt ggaggctgag
      361 gatgttgggg tttattactg catgcaagat atacagcttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001858             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:26917:13112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001858
VERSION     KCVT01001858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26917:13112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79383.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctga ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001859             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22215:7500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001859
VERSION     KCVT01001859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22215:7500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79384.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          118 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacagtcac tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001860             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5473:10697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001860
VERSION     KCVT01001860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5473:10697"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79385.1"
                     /translation="CMQYRHIPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          108 t
ORIGIN      
        1 acaggggggg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagact
      121 ccattctccc tgtccgttag ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttga atagtgaaga cggaaacacc tatttggatt ggtacctgca gaggccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01001861             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20013:2047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001861
VERSION     KCVT01001861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20013:2047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79386.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaagtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aagtcaaacg ag
//
LOCUS       KCVT01001862             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16652:15993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001862
VERSION     KCVT01001862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16652:15993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79387.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 ccgtctccct gcccgtcacc cttggagagc cggcgcccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt gtattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001863             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6344:10578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001863
VERSION     KCVT01001863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6344:10578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79388.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          101 a          110 c          107 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001864             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:13916:4725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001864
VERSION     KCVT01001864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13916:4725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79389.1"
                     /translation="CQQYDGFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          103 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gttggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaac tggtatcacc agaaaccggg gaaagcccct aaactcctgg
      241 tctattatac aagtcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatgggttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001865             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7659:19936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001865
VERSION     KCVT01001865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7659:19936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79390.1"
                     /translation="CLQGYITPYSF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT           99 a          111 c          109 g           98 t
ORIGIN      
        1 atggggagaa ccactcagga cacagcatgg acatgagggt ccccgctcag ctcctggggc
       61 tccttctgct ctggctccca ggtgccagat gtgacttcca gatgacccag tctccatctt
      121 ccctgtctgc atcggtagga gacagagtca ccatcacttg ccgggcaagt caggacatta
      181 gcgatttttt aagttggtat cagcagaaac caggaaaacc tcctaagcgc ctgatttatg
      241 ctgcatccag tttgcaaagt ggggtcccgt caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcagc ctgaagattt tgcggcttat tactgtctac
      361 agggttatat taccccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01001866             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18316:15106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001866
VERSION     KCVT01001866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18316:15106"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..242
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79391.1"
                     /translation="CQQYNSDWRTF"
     J_segment       250..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           76 a           68 c           81 g           62 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg tcgggcgagt cagggcattc gcagttattt
       61 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac
      121 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtataacag
      241 tgactggcgc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01001867             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8173:18766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001867
VERSION     KCVT01001867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8173:18766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79392.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          123 c          116 g           94 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gttcacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaacgtcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agcggggcag ggacagactt cacactgaaa atcagcagag tggaggctga ggatgttgga
      361 atttattact gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01001868             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18441:10345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001868
VERSION     KCVT01001868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18441:10345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..440
                     /note="immunoglobulin light chain variable region"
     V_region        104..440
     V_segment       104..402
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79393.1"
                     /translation="CMQGLQTPYTF"
     J_segment       403..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          105 t
ORIGIN      
        1 acatgggggg actgatcagg actcctcagt tcaccttgtc acaatgaggc tccctgctca
       61 gctcctgggg ctgctaatgc tctgggtctc tgcctccagt ggagatatcg tgatgaccca
      121 gactccactc tcgctgcccg tcacccttgg agagccagcc tccatctcct gcaggtctag
      181 tcagagcctt ctgaatagta atggatacag ctatttgagt tggtacctgc agaggccagg
      241 ccagtctcca catctgctga tctattatgg ctctagtcgg gcctccgggg tccccgacag
      301 gttcagtggc agtgggtcag gcacagattt tacactgaaa atcaccaggg tggaggctga
      361 cgacgtaggg gtttattact gcatgcaagg tctacaaact ccgtacactt ttggccaggg
      421 gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01001869             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21629:20679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001869
VERSION     KCVT01001869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21629:20679"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79394.1"
                     /translation="CQRYGYSTWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          119 c          115 g           91 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gaatgttggc agcagcttag tttggtacca gcagaaacct gggcaggccc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagagg tatggttact ccacgtggac gttcggacaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001870             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14034:14645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001870
VERSION     KCVT01001870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14034:14645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..328
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79395.1"
                     /translation="CQQYNSLPYSF"
     J_segment       329..366
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           93 a           91 c           94 g           91 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc
       61 agtctccatc ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa
      121 gtcagggcgt taacgtttat ttaaattggt atcaacagaa accggggaaa gcccctaagc
      181 ccctgatctt ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt
      301 attattgtca acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga
      361 tcaaacgag
//
LOCUS       KCVT01001871             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19520:3057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001871
VERSION     KCVT01001871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19520:3057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79396.1"
                     /translation="CQHSFRTPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          116 c          112 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcaat gtcacttgca gggctagtga
      181 gagcgttagc accaaattac attggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcgtccactt tgcaaagtgg ggtcccatca agggtcagcg gcagtggatc
      301 tggaacagat ttcactctca ccatcagcag cctgcagcct gaagatgtcg caacttttta
      361 ctgtcagcat agttttcgta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001872             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21164:13927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001872
VERSION     KCVT01001872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21164:13927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79397.1"
                     /translation="CQHSHGSPITF"
     J_segment       262..297
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           81 a           72 c           76 g           71 t
ORIGIN      
        1 acatggggtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgagaacg
       61 tttacaacta tttacattgg tatcagcaga aaccagggaa agcccctaag gtcctgatct
      121 atgctgcatc cactttgcaa agtggagtcc catcaaggtt cagcggcagt ggatctggga
      181 ctgatttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      241 agcatagtca tggatcccct atcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001873             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4044:12267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001873
VERSION     KCVT01001873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4044:12267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79398.1"
                     /translation="CQQGNSNPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          111 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctga ctcccaggtg ccagatgtga cattcagatg tcccagtttc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tatactatgg aaaaagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtaat cctctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001874             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18715:18282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001874
VERSION     KCVT01001874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18715:18282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79399.1"
                     /translation="CMQSLEIPPTF"
     J_segment       401..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           91 a          120 c          124 g          103 t
ORIGIN      
        1 acatggggga cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtcg agtcagagcc
      181 tcttggatgg tggggatgga aacacctatt tggattggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagccact gatttcacac tgaaaatcag cagggtggag gctgaggatg
      361 ttggggttta ttactgcatg caatctctag agattcctcc cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01001875             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14473:16542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001875
VERSION     KCVT01001875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14473:16542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79400.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          118 c          101 g           94 t
ORIGIN      
        1 actggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaacccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgag gattttgcaa cttattactg
      361 tcaacaatat aacagtgacc cattcacttt cggccccggg accaaactgg ataccaaacg
      421 ag
//
LOCUS       KCVT01001876             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9724:18142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001876
VERSION     KCVT01001876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9724:18142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79401.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcgtggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01001877             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24547:21808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001877
VERSION     KCVT01001877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24547:21808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79402.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001878             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10880:8458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001878
VERSION     KCVT01001878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10880:8458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79403.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>426
                     /gene="IGKC"
BASE COUNT          100 a          121 c          118 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctttgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aaggag
//
LOCUS       KCVT01001879             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7325:4764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001879
VERSION     KCVT01001879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7325:4764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79404.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          118 c          113 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaactgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001880             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5612:17128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001880
VERSION     KCVT01001880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5612:17128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..433
                     /note="immunoglobulin light chain variable region"
     V_region        94..433
     V_segment       94..395
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79405.1"
                     /translation="CQQYYSTPWTF"
     J_segment       396..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          104 a          111 c          121 g          100 t
ORIGIN      
        1 acatggggac aacaggcagg caggggcagc aagatggtgt cacagaccca agtcttcatt
       61 tccctgttgc tctggatctc tggtgcctgt ggggacattg tgatgaccca gtcgccagac
      121 tccctggctg tgtctctggg agagagggtc accatcaact gcaagtccag ccagagtctt
      181 ttacgcgtct ccaacaatag gaactactta gcctggtatc agcagaaacc agggcaggct
      241 cctaaattgc tcatttactg ggcatctacc cgggaattcg ggatccctaa ccgattcagt
      301 ggcagtggat ctgggtcaga tttcactctc accatcagtg gcctgcaggc tgaagatgtg
      361 gcagtgtatt actgtcagca gtattatagc actccgtgga cgttcggcca agggaccaag
      421 gtggaaatca aacgag
//
LOCUS       KCVT01001881             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17208:14482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001881
VERSION     KCVT01001881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17208:14482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79406.1"
                     /translation="CQQGYNTPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          117 c          116 g           90 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 gtattagcag ctggttagcc tggtatcagc agaaaccagg gcaagcccct aatctcctga
      241 tctataaggc gtccagtttg gcaagtgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacaggg ttacaatacc ccgtggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001882             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14754:7716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001882
VERSION     KCVT01001882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14754:7716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..364
                     /note="immunoglobulin light chain variable region"
     V_region        43..364
     V_segment       43..326
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79407.1"
                     /translation="CQQYHSLPWTF"
     J_segment       327..364
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           95 a           94 c           92 g           86 t
ORIGIN      
        1 acatgggggc tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag
       61 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg ccgggcaagt
      121 caggacatta gcaattattt aaattggtat cagcagaaac cggggaaagc ccctaacctc
      181 ctgatctatt atacaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc agcctgcaac ctgaggattt tgcgagttat
      301 tactgtcaac agtatcatag tttgccgtgg acgttcggcc aagggaccaa ggtggaaatc
      361 aaacgag
//
LOCUS       KCVT01001883             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18046:12163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001883
VERSION     KCVT01001883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18046:12163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..362
                     /note="immunoglobulin light chain variable region"
     V_region        41..362
     V_segment       41..324
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <302..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79408.1"
                     /translation="CLQGYSPPWTF"
     J_segment       325..362
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           90 a           96 c           92 g           87 t
ORIGIN      
        1 acatggggtc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
       61 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      121 gggcatttac gattatttaa gttggtatca gcaaaaacca ggaaaagctc ctaagcgcct
      181 gatctatgct gcatccagtt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      241 tgggacagaa ttcactctca tcatcagcac cctgcagcct gaagattttg caacttatta
      301 ctgtctacag ggttatagtc ccccgtggac gttcggccaa gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01001884             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18594:13566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001884
VERSION     KCVT01001884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18594:13566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79409.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          118 g          107 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat caccagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01001885             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22487:11432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001885
VERSION     KCVT01001885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22487:11432"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79410.1"
                     /translation="CMQGTHLPFTF"
     J_segment       390..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          120 c          110 g          101 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtctatca ctcttggaca accggcctcc atttcctgca ggcctagtca cacccttgta
      181 cacagtgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggagtt
      361 tattactgca tgcaaggtac acaccttcca ttcactttcg gccccgggac caaactggat
      421 atcaaacgag
//
LOCUS       KCVT01001886             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:9624:16914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001886
VERSION     KCVT01001886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9624:16914"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79411.1"
                     /translation="CMQTLEFPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           94 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccgg tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgtaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggattggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aaactctaga gtttcctctc actttcggcg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01001887             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20805:6835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001887
VERSION     KCVT01001887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20805:6835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79412.1"
                     /translation="CMQALEFPLTF"
     J_segment       313..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           82 a           87 c           99 g           84 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac tcttggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctgca gaaaccaggc cagtctccac gactcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagtttc ctctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001888             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23830:2486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001888
VERSION     KCVT01001888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23830:2486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79413.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcca gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001889             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19311:6336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001889
VERSION     KCVT01001889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19311:6336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79414.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001890             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5242:11166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001890
VERSION     KCVT01001890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5242:11166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..372
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79415.1"
                     /translation="CEQYNSLPYTF"
     J_segment       373..410
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          108 a          108 c          101 g           96 t
ORIGIN      
        1 acatggggag tcaggacaca gcatggacat gagggtcccc gctcagctcc tggggctcct
       61 gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc catcctccct
      121 gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg acgttaacat
      181 ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga tctattatac
      241 aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcaacctga agattttgca acttattact gtgaacaata
      361 caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01001891             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21904:15250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001891
VERSION     KCVT01001891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21904:15250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..396
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79416.1"
                     /translation="CMQGLQTPYTF"
     J_segment       397..434
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggat caggactcct cagttcacct tgtcacaatg aggctccctg ctcagctcct
       61 ggggctgcta atgctctggg tctctgcctc cagtggagat atcgtgatga cccagactcc
      121 actctcgctg cccgtcaccc ttggagagcc agcctccatc tcctgcaggt ctagtcagag
      181 ccttctgaat agtaatggat acagctattt gagttggtac ctgcagaggc caggccagtc
      241 tccacatctg ctgatctatt atggctctag tcgggcctcc ggggtccccg acaggttcag
      301 tggcagtggg tcaggcacag attttacact gaaaatcacc agggtggagg ctgacgacgt
      361 aggggtttat tactgcatgc aaggtctaca aactccgtac acttttggcc aggggaccaa
      421 agtggagatc aaacgag
//
LOCUS       KCVT01001892             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15607:4913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001892
VERSION     KCVT01001892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15607:4913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..367
                     /note="immunoglobulin light chain variable region"
     V_region        28..367
     V_segment       28..330
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <307..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79417.1"
                     /translation="CMQALEFPLTF"
     J_segment       331..367
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           84 a           95 c          103 g           88 t
ORIGIN      
        1 acatgggggc tccctggatc cactggggac attgtgctga cccagactcc actctccctg
       61 cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa cctcttggat
      121 agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca gtctccacag
      181 ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt cagtggcagt
      241 gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      301 tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac caaggtggag
      361 atcaaacgag
//
LOCUS       KCVT01001893             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17551:4810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001893
VERSION     KCVT01001893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17551:4810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..273
                     /note="immunoglobulin light chain variable region"
     V_region        8..273
     V_segment       8..236
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <213..>245
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79418.1"
                     /translation="CMQGLEFPRTF"
     J_segment       238..273
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        274..>276
                     /gene="IGKC"
BASE COUNT           69 a           60 c           83 g           64 t
ORIGIN      
        1 acatgggtag tcagagtctc ttggatagtg cggatggaaa cacctatttg gaatggtacc
       61 tgcagaagcc aggccagtct ccacagctct tgatttatga ggtctccgac cgggcctctg
      121 gagtcccaga caggttcagt ggcagtggct cagacactga tttcacacta aagatcagca
      181 gagtggaggc tgaggatgtt ggggtttatt actgcatgca aggtctagag tttcctcgga
      241 cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01001894             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:7633:14295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001894
VERSION     KCVT01001894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7633:14295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79419.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcac tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001895             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12329:9873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001895
VERSION     KCVT01001895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12329:9873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79420.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccattggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggttcctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01001896             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:2713:8473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001896
VERSION     KCVT01001896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:2713:8473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79421.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          125 c          109 g           85 t
ORIGIN      
        1 acatggggaa ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcaac agcttagcct ggtaccaaca aaaacctggg cagcctccca ggctcctcat
      241 ctatggtgca tccagcaggg ccactggcat cccagacagg ttcagaggca gtgggtctgg
      301 gacagacttc actctcacca tcaccagcct ggagcctgaa gatgttgcag tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001897             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:7006:7698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001897
VERSION     KCVT01001897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7006:7698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79422.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001898             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10460:4502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001898
VERSION     KCVT01001898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10460:4502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79423.1"
                     /translation="CQQRYRFPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           93 a          115 c          112 g          105 t
ORIGIN      
        1 acatgggggg agttagaccc agtctggacg cagcatggac atcagggtcc tcgctcagct
       61 tctcgggctc ctgctgctct ggctcccagg ttccagatgt gacattcagt tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgtc gggccagtca
      181 gggcattagc aattatttag cctggtatca gcagaaacta gggaaagccc ctaacctcct
      241 gatctataag gcgtccagtt tgcagactgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg cagtttatta
      361 ctgtcaacaa cgttatcgtt tcccgctcac tttcggtgga gggaccaggg tggagatcaa
      421 acgag
//
LOCUS       KCVT01001899             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6503:11510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001899
VERSION     KCVT01001899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6503:11510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..237
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79424.1"
                     /translation="CQQYNSDPYTF"
     J_segment       238..275
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           73 a           65 c           76 g           64 t
ORIGIN      
        1 acatggggtc accatcactt gtcgggcgag tcagggcgtt agaagttatt tagcgtggta
       61 tcagctgaga ccagggaaag ccccgaaggc cttaatctat tacgcgacca ttttggaaag
      121 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      181 cagcctgcag cctgaggatt ttgcaactta tttctgtcaa cagtataaca gtgacccgta
      241 cacttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01001900             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:26821:18554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001900
VERSION     KCVT01001900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26821:18554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79425.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgttacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001901             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9707:10124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001901
VERSION     KCVT01001901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9707:10124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79426.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          112 a          117 c          104 g           87 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcacgata
      181 ttaacaactg gttggcctgg tatcaacaga aaccagggaa agcccctaag gtcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggttctggga
      301 cagatttcac tctcaccatc aacaacctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacaacatga tgattcccct cggaccttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001902             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11456:20194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001902
VERSION     KCVT01001902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11456:20194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79427.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          126 c          110 g           89 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccat cacaaacctg ggcaggctcc caagctcctc
      241 ctctttggtg catccaccag ggccaccggc atcccagaca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001903             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10734:10827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001903
VERSION     KCVT01001903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10734:10827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79428.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtgt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atcttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001904             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:26419:14209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001904
VERSION     KCVT01001904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:26419:14209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79429.1"
                     /translation="CMQSLELPFTF"
     J_segment       265..302
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           72 a           73 c           87 g           73 t
ORIGIN      
        1 acatggggga gagccggcgt ccatctcctg taggtctagt cagagcctcg tggatagtga
       61 ggatggaaac acctatttgg aatggttcct gcagaggcca ggccagtctc cacagctctt
      121 gatttatgac gtttccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      181 agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg gggtttatta
      241 ctgcatgcaa tctctagagc ttccattcac tttcggcccc gggaccaaac tggatatcaa
      301 acgag
//
LOCUS       KCVT01001905             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13695:8400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001905
VERSION     KCVT01001905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13695:8400"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..278
                     /note="immunoglobulin light chain variable region"
     V_region        8..278
     V_segment       8..240
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79430.1"
                     /translation="CEQYNSLPYTF"
     J_segment       241..278
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>281
                     /gene="IGKC"
BASE COUNT           86 a           66 c           63 g           66 t
ORIGIN      
        1 acatgggaga gtcaccatca cttgccgggc aagtcaggac attaacattt atttaaattg
       61 gtatcaccag aaaccgggga aagcccctaa gctcctgatc tattatacaa accgtttgga
      121 aactggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat
      181 cagcagcctg caacctgaag attttgcaac ttattactgt gaacaataca atagtttacc
      241 gtacactttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01001906             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13246:17290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001906
VERSION     KCVT01001906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13246:17290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79431.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          116 c          110 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 gatattaaca actggttggc ctggtatcaa cagaaaccag ggaaagcccc taaggtcctg
      241 atctataggg catccatttt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001907             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23447:14178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001907
VERSION     KCVT01001907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23447:14178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79432.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcatccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccaccttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001908             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:7741:8638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001908
VERSION     KCVT01001908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7741:8638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79433.1"
                     /translation="CQQYNSLPYIF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          110 c          104 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgttttt ttaaattggt atcagcagaa accggggaaa gcccctaaac ccctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat agtttaccgt acatttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001909             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22485:17656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001909
VERSION     KCVT01001909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22485:17656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79434.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttggcg tggtatcacc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01001910             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8127:4363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001910
VERSION     KCVT01001910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8127:4363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79435.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgagtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001911             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8834:7093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001911
VERSION     KCVT01001911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8834:7093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..383
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79436.1"
                     /translation="CQQYSDFLLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           95 a          126 c          111 g           92 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gatcccagat accgccggaa aaattgtcat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa acagccaccc tctcctgcag ggccagtgag
      181 agtgttggca ccttcttagc ctggtaccaa cagaaacctg ggcaggctcc caagctcctt
      241 gtccatagtg ctttcttcag ggcccctggc atcccagaca ggttcagtgg cagcgggtct
      301 aggacagagt tcactctcac catcaacacc ctggagcctg aagatgttgg agtttatcac
      361 tgtcagcagt atagtgactt cctgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001912             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21863:20758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001912
VERSION     KCVT01001912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21863:20758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79437.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacgt atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001913             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15144:12631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001913
VERSION     KCVT01001913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15144:12631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79438.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctacatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01001914             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11836:9817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001914
VERSION     KCVT01001914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11836:9817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79439.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          125 c          112 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01001915             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21935:17479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001915
VERSION     KCVT01001915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21935:17479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79440.1"
                     /translation="CQQGYSFPFTF"
     J_segment       380..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           94 a          121 c          105 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcagtagt ttaagctggt atcagcagaa accagggaaa gcccctaacc tcctgatctt
      241 tagggcatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctcca gcctgaagat tttgccactt attactgtca
      361 acagggttat agtttcccct tcactttcgg cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01001916             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:8965:14472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001916
VERSION     KCVT01001916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8965:14472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79441.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagtcaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01001917             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15982:14351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001917
VERSION     KCVT01001917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15982:14351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79442.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          115 c          109 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcaggatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atccaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcgcctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01001918             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:26674:9457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001918
VERSION     KCVT01001918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:26674:9457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..378
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79443.1"
                     /translation="CYQHSRGWAF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT           97 a          121 c          115 g           84 t
ORIGIN      
        1 acatggggct gctaggttag tacccagaag gaaccatgga agccccagct cagcttctct
       61 gccttctgct actctggctc ccaggtacca ccggacaaat tatattgaca cagtctccag
      121 ccaccctgtc tttggcacca ggggaaagag ccactctctc ctgcagggcc agtgagaatg
      181 ttggcagcta cttagcctgg taccagcaga accctgggca ggctcccagg ctcctcgtcc
      241 acagtgcgtc cagcagggcc actgatatcc cagacaggtt cagtggcagt gggtctcgga
      301 cagagttcac cctcaccatc agcagtctgg agcctgaaga tgttggagtc tattactgct
      361 atcaacatag cagggggtgg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01001919             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9700:24497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001919
VERSION     KCVT01001919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9700:24497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79444.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagaccggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01001920             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:4708:9333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001920
VERSION     KCVT01001920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:4708:9333"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79445.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcaa catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001921             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13031:4915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001921
VERSION     KCVT01001921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13031:4915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79446.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01001922             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19660:3064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001922
VERSION     KCVT01001922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19660:3064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79447.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 tcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001923             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22539:15332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001923
VERSION     KCVT01001923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22539:15332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79448.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgaa gatggaaata cctatttgga atggcaccgg cagatgccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcactctgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctgacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01001924             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5638:4988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001924
VERSION     KCVT01001924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5638:4988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79449.1"
                     /translation="CLQYRSYPYNF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          111 c          105 g           97 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg taggagacac tgtcaccatc acttgccggg caagtcagga
      181 tattagcagt tatttaaatt ggtttcagaa gaaaccaggg aaagccccta agctcctgat
      241 ccaagctgca tccagtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tctacagtat agaagttacc cgtacaattt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001925             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7305:5351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001925
VERSION     KCVT01001925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7305:5351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79450.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag cttggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001926             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17516:13572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001926
VERSION     KCVT01001926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17516:13572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79451.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atattggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001927             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6030:8791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001927
VERSION     KCVT01001927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6030:8791"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..313
                     /note="immunoglobulin light chain variable region"
     V_region        114..313
     V_segment       114..276
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79452.1"
                     /translation="CMQALEFPLTF"
     J_segment       277..313
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           72 a           79 c           86 g           79 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccacagctct tgatttatga agtttccaat cgggcctctg gagtcccaga caggttcagt
      181 ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt
      241 ggggtttatt actgcatgca agctctagaa tttcctctca ctttcggtgg agggaccaag
      301 gtggagatca aacgag
//
LOCUS       KCVT01001928             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21657:18191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001928
VERSION     KCVT01001928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21657:18191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79453.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          125 c          118 g          102 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccaatgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttgcag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatactgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtcccc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggcccag
      421 ggaccaaggt ggacatcaaa cgag
//
LOCUS       KCVT01001929             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17436:10500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001929
VERSION     KCVT01001929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17436:10500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79454.1"
                     /translation="CLQDIQLPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           88 a          123 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattatgat gactcagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc ataggaatgg gtacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacagc tcctgatcta tttcggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtgccagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgctt gcaagatata caacttccgc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01001930             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:27438:6265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001930
VERSION     KCVT01001930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:27438:6265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79455.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tcgagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actggtttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001931             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17801:13425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001931
VERSION     KCVT01001931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17801:13425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79456.1"
                     /translation="CQQYDSDPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagtccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01001932             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:25027:12311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001932
VERSION     KCVT01001932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25027:12311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79457.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctactg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001933             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:4448:15585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001933
VERSION     KCVT01001933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4448:15585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79458.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001934             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5240:13395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001934
VERSION     KCVT01001934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5240:13395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..447
                     /note="immunoglobulin light chain variable region"
     V_region        108..447
     V_segment       108..409
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <387..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79459.1"
                     /translation="CMQALQFPWTF"
     J_segment       410..447
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>450
                     /gene="IGKC"
BASE COUNT           97 a          125 c          117 g          111 t
ORIGIN      
        1 ctaaccttgc cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg
       61 ctcagctcct gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga
      121 cccagactcc actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt
      181 ctagtcagag cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga
      241 ggccaggcca gtctccacac ctcttgattt atgagttttc caatcgggcc tctggagtcc
      301 cagacaggtt cagtggcagt gggtcagaca ctgatttcac tctgaatatc agcagagtgg
      361 aggctgagga tgttggggtt tattactgca tgcaagctct acaatttccg tggacgttcg
      421 gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001935             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6481:10843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001935
VERSION     KCVT01001935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6481:10843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79460.1"
                     /translation="CQQGYRYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          104 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tgacattaat ttaaattact atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc cgtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agatacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001936             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11457:10528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001936
VERSION     KCVT01001936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11457:10528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79461.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          118 c          106 g           91 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatatc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001937             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13251:17706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001937
VERSION     KCVT01001937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13251:17706"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79462.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          112 c          101 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacgtttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01001938             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18270:14992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001938
VERSION     KCVT01001938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18270:14992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79463.1"
                     /translation="CQQHDNAPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          116 c          114 g           85 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcagcagca tgacaatgcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001939             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19906:5401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001939
VERSION     KCVT01001939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19906:5401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79464.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          112 c          117 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tctccatctc ctgccaagcc agagcagatg
      181 tacatggtga aatatcttgg atccggataa accttgaaca aagacttgaa ccccatttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagaccggtt catcagcaag gggggtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01001940             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:27896:16304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001940
VERSION     KCVT01001940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27896:16304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79465.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          118 c          108 g           86 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gcctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattaacac ctggttggcc tggtatcaac agaagccagg gaaagcccct aaggtcctga
      241 tctataggac atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcaacagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001941             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14199:21531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001941
VERSION     KCVT01001941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14199:21531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79466.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactact aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001942             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16332:10663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001942
VERSION     KCVT01001942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16332:10663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79467.1"
                     /translation="CLQSKDSPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           98 a          115 c          116 g          101 t
ORIGIN      
        1 acatgggggc agcctctagt tcagctctca gaaatggggt cctgggctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggatgcaat ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accatcacct gcagagccag tgagagtgtc
      181 agtttgtttg gaataagcct cattcactgg tatcagcaga aaccaggaca acctcccaaa
      241 ctcctgattt accaagcatt cactacagag actggggtcc cagtcaagtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aaggtgacga tgccgcagat
      361 tatttctgtc tgcagagtaa ggattctccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01001943             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14092:8370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001943
VERSION     KCVT01001943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14092:8370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79468.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01001944             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:20211:16175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001944
VERSION     KCVT01001944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20211:16175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79469.1"
                     /translation="CQQYNTLPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          117 c          102 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg agattcagat gacccagtct
      121 ccatcctccc tgtctgcctc tgtcggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagta attatttaaa ttggtatcag cagagaccgg ggaaagcccc taaactcctg
      241 atctattatg catcccgttt ggaaaacggg gtcccatcaa agttcagcgg cagtggatct
      301 gggacagaat tcagtctcac catcagtagc ctgcaacctg aagattttgc aacttattac
      361 tgtcagcagt ataatacctt accattcact ttcggccccg ggaccaaact ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001945             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12946:15775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001945
VERSION     KCVT01001945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12946:15775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79470.1"
                     /translation="CQQYNALPLTF"
     J_segment       383..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>420
                     /gene="IGKC"
BASE COUNT          106 a          109 c          109 g           96 t
ORIGIN      
        1 acatggggga gacccagtca ggacacggca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttagtaatta tttaaattgg tatcaacaga aaccggggaa agcccctaag gtcctcatct
      241 attatacaaa ccgtttggaa agtggggtcc catcaaggtt cattggcagt ggatctggga
      301 cagagttcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tactactgtc
      361 aacagtataa tgctttaccg ttgacgttcg gccaagggac cagggtggaa atcaaaggag
//
LOCUS       KCVT01001946             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:27048:7187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001946
VERSION     KCVT01001946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27048:7187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79471.1"
                     /translation="CQQYNSFPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          108 c          110 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcaa gtcagggcat
      181 tagcgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgtaggtt attactgtca
      361 acagtataat agttttccgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001947             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15568:9797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001947
VERSION     KCVT01001947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15568:9797"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79472.1"
                     /translation="CQQGYGFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          119 c          103 g          102 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcgcgat cacttgcctg gcgagtcaag
      181 gcattggcaa taatttaaat tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctatacggc atccaattta catggtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcaacagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatggtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001948             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22508:18729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001948
VERSION     KCVT01001948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22508:18729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79473.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           95 a          127 c          110 g           94 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagtcac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01001949             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20530:6430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001949
VERSION     KCVT01001949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20530:6430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79474.1"
                     /translation="CQQYNSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          114 c          107 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gcagaaacca ggaaaagccc cgaaggcctt
      241 gatctattac gcatccattt tagaaagtgc ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagtct gacgattttg caacttatta
      361 ctgtcaacaa tataacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01001950             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:4486:8215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001950
VERSION     KCVT01001950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4486:8215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..368
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79475.1"
                     /translation="CQQVLTNPAF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          112 c          106 g          100 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccaggtg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag gaatttagcg tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctatgctgc atccagattg caaagtgggt ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcaacc tacagcctga agattctgca atttattact
      361 gtcaacaggt tcttactaat ccggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01001951             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18362:14805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001951
VERSION     KCVT01001951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18362:14805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79476.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001952             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18099:16472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001952
VERSION     KCVT01001952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18099:16472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79477.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          116 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggt ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001953             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7192:12187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001953
VERSION     KCVT01001953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7192:12187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79478.1"
                     /translation="CQQYDSYSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagttatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01001954             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19498:11986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001954
VERSION     KCVT01001954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19498:11986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79479.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          127 c          109 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga gagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctttggt acatccacca ggaccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tcgaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001955             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14566:17399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001955
VERSION     KCVT01001955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14566:17399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79480.1"
                     /translation="CGQGTHLPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g           96 t
ORIGIN      
        1 acatgggggt ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgatgactc agtctccact
      121 ctccctgtcc atcacccctg gacagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tgtacacatc aatggaaaca catacttgag ttggtatcag cagaacccag gccaacctcc
      241 aaggcgccta atttatgagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 gctttattac tgcgggcaag gtacacacct tccgtggacg ttcggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01001956             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19024:15986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001956
VERSION     KCVT01001956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19024:15986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79481.1"
                     /translation="CQQYNNDPPTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          123 c          103 g           90 t
ORIGIN      
        1 acagggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagcag tcatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagactt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacaatgac cctcccactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01001957             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4319:12651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001957
VERSION     KCVT01001957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4319:12651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79482.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaacccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaatttatt
      361 actgtcaaca gtatgacagt gacccgttta ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01001958             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16450:8116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001958
VERSION     KCVT01001958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16450:8116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..391
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79483.1"
                     /translation="CLQGYTIPYTF"
     J_segment       406..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          112 a          120 c          113 g          101 t
ORIGIN      
        1 acatggggac gctggtcaca cttcatgtag gagtcagaac cactcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct ccttctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacccagt ctccatcttc cctgtctgca tcggtaggag acagagtcac
      181 catcacttgc cggacaagtc agggcattag cgattattta agttggtatc agcagaaacc
      241 aggaaaagct cctaagcgcc tgatccatgc tgtatccagt ttggaaagtg gggccccatc
      301 aaggttcagc ggcagtggat ctgaaacaga gttcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtctaca gggttatact atcccgtaca cttttggcca
      421 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01001959             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18653:12783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001959
VERSION     KCVT01001959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18653:12783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79484.1"
                     /translation="CEQYNSLPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          110 a          111 c          103 g           96 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggacg
      181 ttaacattta tttaaattgg tatcaccaga aaccggggaa agcccctaag ctcctgatct
      241 attatacaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcaact tattactgtg
      361 aacaatacaa tagtttaccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01001960             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11936:2666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001960
VERSION     KCVT01001960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11936:2666"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..341
                     /note="immunoglobulin light chain variable region"
     V_region        20..341
     V_segment       20..303
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79485.1"
                     /translation="CEQYNSLPYTF"
     J_segment       304..341
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           98 a           84 c           79 g           83 t
ORIGIN      
        1 acatgggggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgcttc
       61 tgtaggagac agagtcacca tcacttgccg ggcaagtcag gacattaaca tttatttaaa
      121 ttggtatcac cagaaaccgg ggaaagcccc taagctcctg atctattata caaaccgttt
      181 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      241 catcagcagc ctgcaacctg aagattttgc aacttattac tgtgaacaat acaatagttt
      301 accgtacact tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01001961             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10081:2515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001961
VERSION     KCVT01001961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10081:2515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79486.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          126 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcgcc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01001962             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10962:12262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001962
VERSION     KCVT01001962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10962:12262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..397
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79487.1"
                     /translation="CHQGNSFPWTF"
     J_segment       398..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          113 a          110 c          113 g          102 t
ORIGIN      
        1 acatggggct ctgggatgtg gcatgagcaa aactgacaag tcaaggcagg aagatgttgt
       61 ctccatcaca actcattggg tttctgctgc tctgggttcc agcctccaag ggtgaaattg
      121 tgctgactca gtctccagtc tttcggtctg tgagtctaaa ggagaaagtc accatcacct
      181 gccaggccag tcagaacatt ggtaataagc tacactggta ccagcagaaa ccggatcagt
      241 ctccaaagct cctcatcaag tatgcttccc agtccatctc aggggtcccc tcaaggttca
      301 gtggcagtgg atctgggaca gatttcaccc ttaccatcaa tagcctggaa gctgaagacg
      361 ctgcgacgta ttactgtcac cagggtaata gttttccgtg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01001963             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12947:7640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001963
VERSION     KCVT01001963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12947:7640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79488.1"
                     /translation="CMQALDFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          118 c          125 g          105 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatctagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg taggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 gggcagtctc cacaactctt gatttatgag gtttccgacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctggact ttccgtggac gttcggccaa
      421 gggaccaagg tggaagtcaa acgag
//
LOCUS       KCVT01001964             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19858:10502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001964
VERSION     KCVT01001964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19858:10502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79489.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001965             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17092:11501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001965
VERSION     KCVT01001965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17092:11501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79490.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctacat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01001966             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:21025:15194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001966
VERSION     KCVT01001966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21025:15194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..250
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79491.1"
                     /translation="CQHSHGSPITF"
     J_segment       252..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           80 a           69 c           74 g           67 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgcagggca agtgagaacg tttacaacta
       61 tttacattgg tatcagcaga aaccagggaa agcccctaag gtcctgatct atgctgcatc
      121 cactttgcaa agtggagtcc catcaaggtt cagcggcagt ggatctggga ctgatttcac
      181 tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc agcatagtca
      241 tggatcccct atcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01001967             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23787:8700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001967
VERSION     KCVT01001967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23787:8700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79492.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          117 c          104 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01001968             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:14666:18261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001968
VERSION     KCVT01001968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14666:18261"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79493.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacttatttc acactgaaaa ttagcagagt ggaggctgag
      361 gatgttgggg ttttttactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001969             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12941:23078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001969
VERSION     KCVT01001969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12941:23078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79494.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccatt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 agcgag
//
LOCUS       KCVT01001970             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14589:18290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001970
VERSION     KCVT01001970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14589:18290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..282
                     /note="immunoglobulin light chain variable region"
     V_region        6..282
     V_segment       6..244
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79495.1"
                     /translation="CQQYNSLPYTF"
     J_segment       245..282
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>285
                     /gene="IGKC"
BASE COUNT           87 a           65 c           66 g           67 t
ORIGIN      
        1 acatggggga cagagtcacc atcacttgcc gggcaagtca ggacactagt atttatttaa
       61 attggtatca acaaaaaccg gggaaagccc ctaagctcct gatctattat ggaaaccgtt
      121 tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca
      181 ccatcaacag cctgcaacct gaagattttg caacttatta ctgtcaacag tataatagtt
      241 taccgtacac ttttggccac gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01001971             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25823:8128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001971
VERSION     KCVT01001971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25823:8128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79496.1"
                     /translation="CQQYDKSPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          118 c          116 g           86 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agggtcacca tcacttgcag agccagtcag
      181 ggtatcagca actggttggc ctggtatcaa cagaaaccag ggagagcccc taacctcctg
      241 atgtataggg cgtccaattt gcaaggaggg gtcccatcaa ggttcagagg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aggatgtcgc tacatattac
      361 tgtcaacagt atgataagtc ccctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01001972             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16035:13922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001972
VERSION     KCVT01001972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16035:13922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79497.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001973             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26844:19883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001973
VERSION     KCVT01001973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26844:19883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79498.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          118 g          110 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga aactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct cttgagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001974             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9389:18812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001974
VERSION     KCVT01001974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9389:18812"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79499.1"
                     /translation="CMQALEFPLTV"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactgtc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001975             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17585:6425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001975
VERSION     KCVT01001975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17585:6425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..367
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79500.1"
                     /translation="CQQGQSYPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttatattggt atcaactgaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc agtttgcaag gtgggagtcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcag agttacccgc tcactttcgg cggagggacc aaggtagaaa tcaaacgag
//
LOCUS       KCVT01001976             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:4138:10372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001976
VERSION     KCVT01001976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:4138:10372"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79501.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctatg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01001977             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22732:15987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001977
VERSION     KCVT01001977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22732:15987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79502.1"
                     /translation="CQQYSDFLLTF"
     J_segment       269..306
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           69 a           89 c           83 g           68 t
ORIGIN      
        1 acatgggagc caccctgtct ttgtctccag gggaaacagc caccctctcc tgcagggcca
       61 gtgagagtgt tggcaccttc ttagcctggt accaacagaa acctgggcag gctcccaaac
      121 tccttgtcca tagtgcattc ttcagggccc ctggcatccc agacaggttc agtggcagcg
      181 ggtctgggac agagttcact ctcaccatca acaccctgga gcctgaagat gttggagttt
      241 atcactgtca gcagtatagt gacttcctgc tcactttcgg cggagggacc aaggtggaga
      301 tcaaacgag
//
LOCUS       KCVT01001978             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:26157:10582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001978
VERSION     KCVT01001978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26157:10582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..442
                     /note="immunoglobulin light chain variable region"
     V_region        100..442
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79503.1"
                     /translation="CMQALEFPPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          123 c          118 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ttgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattattg catgcaagct ctagagtttc ctccattcac tttcggcccc
      421 gggaccaaac tggagatcaa acgag
//
LOCUS       KCVT01001979             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22498:8382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001979
VERSION     KCVT01001979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22498:8382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79504.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttttgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gcgggtcaga cactgatttc aaactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01001980             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12484:3581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001980
VERSION     KCVT01001980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12484:3581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79505.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatacggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01001981             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23190:17849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001981
VERSION     KCVT01001981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23190:17849"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79506.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          109 c          107 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtagtagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtta ttatttaaat tggtatcaac agaaaccggg gaaagcccct aaggtcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca agttattact
      361 gtcaacaata taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01001982             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9821:7714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001982
VERSION     KCVT01001982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9821:7714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79507.1"
                     /translation="CQENNNWPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          125 c          114 g           83 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gagatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcactttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatgat gcatccacca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcaggag aacaataact ggcctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001983             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15279:15689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001983
VERSION     KCVT01001983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15279:15689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79508.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          118 c          109 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagcca
      181 cgatataaat aactggttgg cctggtatca acagaaacca ggaaaagccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca gcatcagcag cctgcagcct gaagatttcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01001984             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11470:19296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001984
VERSION     KCVT01001984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11470:19296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79509.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001985             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6517:12301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001985
VERSION     KCVT01001985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6517:12301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79510.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01001986             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17964:16589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001986
VERSION     KCVT01001986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17964:16589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79511.1"
                     /translation="CQQGYSYHPTF"
     J_segment       386..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>423
                     /gene="IGKC"
BASE COUNT           93 a          120 c          111 g           99 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga cttccttatg acgcagtctc
      121 cttcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattggcac taatttaaat tggtatcagc agagaccagg aaaagcccct aaactcctga
      241 tctatagggc ttccggtttg cagagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cagtctcacc agcggcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac catcccactt tcggcggagg gaccaaggtg gagatccaac
      421 gag
//
LOCUS       KCVT01001987             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20591:11175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001987
VERSION     KCVT01001987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20591:11175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79512.1"
                     /translation="CQQYNSLPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          109 c          109 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccatg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 catcaactat tatttaaatt ggtatcagca gatgccgggg aaagccccta aggtcctgat
      241 ctattataca aatcgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01001988             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11366:9913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001988
VERSION     KCVT01001988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11366:9913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..314
                     /note="immunoglobulin light chain variable region"
     V_region        9..314
     V_segment       9..275
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79513.1"
                     /translation="CQQYDSDLFTF"
     J_segment       279..314
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>317
                     /gene="IGKC"
BASE COUNT           79 a           78 c           84 g           76 t
ORIGIN      
        1 acatggggag tctccatcct ccctgtctgc atttgtagga gacagagtca ccatcacttg
       61 tcgggcgagt cagggcattc gcagttattt agcgtggtat cagcagaaac cagggaaagc
      121 cccgaagccc ttgatctatt acgcgtccac tttggaaagt ggggtcccat caaggttcag
      181 cggcagtggt tctgggacag aattcactct caccatcaac agcctgcagc ctgaagattt
      241 tgcaacttat tactgtcaac agtatgacag tgacctgttc actttcggtg gagggaccaa
      301 ggtggagatc aaacgag
//
LOCUS       KCVT01001989             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20359:14875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001989
VERSION     KCVT01001989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20359:14875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79514.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01001990             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19421:15988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001990
VERSION     KCVT01001990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19421:15988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79515.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           96 a          121 c          123 g          106 t
ORIGIN      
        1 acatgggggg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tgggtccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagaccctc ttggatggtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt gggatttatt actgcatgca agctctagag tttcctctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01001991             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6114:13684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001991
VERSION     KCVT01001991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6114:13684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79516.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          111 c          103 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcaa
      181 gacatttata gttatttaca ttggtatcag cagaaaccgg ggaaagcccc taaactcctg
      241 atctattatt caaaccgttt ggacaaaggg gtcccatcaa ggttcagcgg aagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc atcttatcac
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001992             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22685:18348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001992
VERSION     KCVT01001992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22685:18348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..376
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79517.1"
                     /translation="CQQVYSSPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          114 c          109 g          104 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ctgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gatatccaga tgacccagtc
      121 tccatctgcc ttgtctgcat ctgtgggaga cagagtcacc atctcttgcc gggcaagtca
      181 gaacatttat agttatttag cgtggtatca acagaaacca gggaaagccc ctaagctcct
      241 gatctatgct gtatccagat tgcaaagtgg ggttccctct cggttcagcg gcagtggaac
      301 tgggacagat ttcactctca gcatcagcag cctacagcct gaagattctg ccggttatta
      361 ctgtcaacag gtttatagta gtccattcac tttcggcccc gggaccaaac tggctatcaa
      421 acgag
//
LOCUS       KCVT01001993             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21167:19723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001993
VERSION     KCVT01001993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21167:19723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79518.1"
                     /translation="CMQALDFPYSF"
     J_segment       407..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          108 t
ORIGIN      
        1 acatgggggg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tacagaagcc
      241 aggccagtct ccacagctct tgatttttga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactaa tttcacactg aaaatcagca gtgtggaggc
      361 tgaggatgtt ggggtctatt actgcatgca agctctagac tttccttaca gttttggcca
      421 ggggaccaca gtggagatta aacgag
//
LOCUS       KCVT01001994             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21844:10774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001994
VERSION     KCVT01001994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21844:10774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79519.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tggacaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01001995             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14940:6655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001995
VERSION     KCVT01001995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14940:6655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79520.1"
                     /translation="CQQHNNYSPTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          119 c          104 g           90 t
ORIGIN      
        1 acatgggaga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccaccc
      121 tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag tcagggcatt
      181 agcaatgatt tagcctggta tcagctgaaa ccagggaaag ccccgaagcc cctgatctat
      241 tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagcataata attactctcc cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01001996             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19874:18469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001996
VERSION     KCVT01001996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19874:18469"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79521.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcagggcac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01001997             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18186:12318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001997
VERSION     KCVT01001997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18186:12318"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79522.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01001998             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:7668:7315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001998
VERSION     KCVT01001998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:7668:7315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79523.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01001999             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19270:7262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01001999
VERSION     KCVT01001999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19270:7262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79524.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 aggttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002000             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9743:10282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002000
VERSION     KCVT01002000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9743:10282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <370..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79525.1"
                     /translation="CLQSKNSYSF"
     J_segment       391..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          102 a          112 c          113 g          103 t
ORIGIN      
        1 acatgggggg agcagcctct agttcagctc tcagaaatgg ggtcctgggc tcctttcctg
       61 tggatcctcc tgctctgtgc tccaggctgc aatggggaca ttgtgctgac ccagtctcca
      121 gcctctttgg ccgtgtctcc agggcagagg gccaccatca cctgcagagc cagtgagagt
      181 gtcagtttct ttggaataaa cctcattcac tggtatcagc agaaaccggg acaacctcct
      241 aaactcctga tttaccaaga attcaataaa gacactgggg tcccagccag gttcagcggc
      301 agtgggtctg ggaccgattt caccctcaca attaatcctg tggaagctga cgatgctgca
      361 gattattact gtctgcagag taagaattct tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01002001             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24130:9550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002001
VERSION     KCVT01002001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24130:9550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79526.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          128 c          114 g           84 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga caaatagtgc tgacgcagtc
      121 tccagccacc ctgtccttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcctag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctttggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002002             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19385:11752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002002
VERSION     KCVT01002002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19385:11752"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79527.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc cctgacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002003             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11980:2215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002003
VERSION     KCVT01002003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11980:2215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..398
                     /note="immunoglobulin light chain variable region"
     V_region        101..398
     V_segment       101..360
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79528.1"
                     /translation="CQQYNSLPYIF"
     J_segment       361..398
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>401
                     /gene="IGKC"
BASE COUNT          104 a          104 c          100 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgtca cttgccgggc aagtcaggac attaacgttt atttaaattg
      181 gtatcagcag aaaccgggga aagcccctaa acccctgatc tattatagaa accgtttgga
      241 aagtggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat
      301 cagcagcctg caacctgaag attttgcaac ttattactgt caacagtata atagtttacc
      361 gtacattttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002004             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14832:8370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002004
VERSION     KCVT01002004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14832:8370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79529.1"
                     /translation="CQQYDSDPRTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          118 c          115 g           90 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gcgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgcgca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002005             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15008:5132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002005
VERSION     KCVT01002005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15008:5132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79530.1"
                     /translation="CQQYNSLPYIF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          111 c          105 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg actcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg tttttttaaa ttggtatcag cagaaaccgg ggaaagcccc taaacccctg
      241 atctattatg caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accgtacatt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002006             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:6435:6379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002006
VERSION     KCVT01002006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6435:6379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79531.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002007             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22161:14294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002007
VERSION     KCVT01002007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22161:14294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79532.1"
                     /translation="CLQYKTYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          110 c          105 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tgctggttat ttaaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa acttatccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002008             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16538:3642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002008
VERSION     KCVT01002008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16538:3642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79533.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcaacag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01002009             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13378:7529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002009
VERSION     KCVT01002009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13378:7529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..435
                     /note="immunoglobulin light chain variable region"
     V_region        100..435
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79534.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          120 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttcttacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgta tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgcgga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccagggg
      421 accaaggtgg aaatcgaacg ag
//
LOCUS       KCVT01002010             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19462:14299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002010
VERSION     KCVT01002010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19462:14299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..432
                     /note="immunoglobulin light chain variable region"
     V_region        96..432
     V_segment       96..394
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79535.1"
                     /translation="CVQAIAFPYSF"
     J_segment       395..432
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT           93 a          120 c          121 g          101 t
ORIGIN      
        1 acatggggga ggactcctca gttcaccttc tcacaatgag gctccctgct cagttcctgg
       61 ggctgctgat gctctggctc cctggatcca gtggggatat tgtgatgacc cagactccac
      121 tctccctgtc catcacccct ggagagccgg cctccatctc ctgcaggtct agtcagagcc
      181 tcctgcatag taatggaaac acctatttcc actggtacct gcagaagcca ggccagtctc
      241 cgcagcccct gatttatggg ggttccaaca gagcctctgg agtcccagac aggttcagtg
      301 gcagtgggtc aggcactgat ttcacactga aaatcagcaa ggtggaggcg gaggatgttg
      361 gggtttatta ctgcgtgcaa gctatagcgt ttccgtacag ttttggccag gggaccaaag
      421 tggagatcaa acgag
//
LOCUS       KCVT01002011             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12143:8362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002011
VERSION     KCVT01002011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12143:8362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79536.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          121 c          109 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgaa
//
LOCUS       KCVT01002012             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5986:10366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002012
VERSION     KCVT01002012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5986:10366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79537.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          125 c          109 g           85 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcaaca gcttagcctg gtaccaacaa aaacctgggc agcctcccag gctcctcatc
      241 tatggtgcat ccagcagggc cactggcatc ccagacaggt tcagaggcag tgggtctggg
      301 acagacttca ctctcaccat caccagcctg gagcctgaag atgttgcagt ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01002013             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13555:16243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002013
VERSION     KCVT01002013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13555:16243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79538.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          123 c          115 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002014             385 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18143:12945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002014
VERSION     KCVT01002014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 385)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18143:12945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..382
                     /note="immunoglobulin light chain variable region"
     V_region        43..382
     V_segment       43..344
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <322..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79539.1"
                     /translation="CVQSSHIPFTF"
     J_segment       347..382
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>385
                     /gene="IGKC"
BASE COUNT           83 a          104 c          106 g           92 t
ORIGIN      
        1 acatgggggc tgctaatgct ctggctctct ggatccagtg gggatattct gatgacccag
       61 gctccactct ccctgcccgt cacccctgga gagccggcct ccatctcctg caggtctagt
      121 cagagcctct tggatagtga agatggaaac acctatttgg attggtacct ccagaagccg
      181 ggccagtctc cacagccctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      241 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatccgcag agtgcaggct
      301 gaggatgttg gagtttatta ctgcgtgcaa tcttcacaca ttccgttcac tttcggcgga
      361 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002015             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11153:9334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002015
VERSION     KCVT01002015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11153:9334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79540.1"
                     /translation="CQQGYRYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          104 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcctctgtgg gagacacagt cacgatcact tgccaggcga gtcaagacat
      181 tgacattaat ttaaattact atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc cgtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat cgttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002016             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11739:5311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002016
VERSION     KCVT01002016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11739:5311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    71..389
                     /note="immunoglobulin light chain variable region"
     V_region        71..389
     V_segment       71..354
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79541.1"
                     /translation="CQQYDDYPWTF"
     J_segment       355..389
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>395
                     /gene="IGKC"
BASE COUNT           92 a          107 c          107 g           89 t
ORIGIN      
        1 acatggggac atgagggtcc ccgctcagtt cctggggctc ctgctgctct ggctcccagg
       61 tgccagatgt gacatccaga tgacccagtc tccatcctac ctgtctgcat ctgtaggaga
      121 caaagtcacc atcacttgcc atgccagtca gggtatcagt agtcggttag tctggtatca
      181 gcagaaacca ggggaagccc ctaagtccct gatgtatgct gcatccagtt tacacagtgg
      241 ggtcccatca aggttcagcg gcagtggatc tgggagggat tacacactca ccatcggcag
      301 cctgcagcct gaagattttg caacttatta ctgtcaacag tatgatgatt acccgtggac
      361 gttcggccaa gggaccaagg tggaaatcac gcgag
//
LOCUS       KCVT01002017             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22265:15410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002017
VERSION     KCVT01002017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22265:15410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79542.1"
                     /translation="CLQGYITPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          113 c          109 g          100 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaacctgg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg ttatattacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002018             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15913:7363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002018
VERSION     KCVT01002018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15913:7363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79543.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggag ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002019             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15606:17747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002019
VERSION     KCVT01002019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15606:17747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79544.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagttgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002020             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16551:4790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002020
VERSION     KCVT01002020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16551:4790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79545.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          116 c          107 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gtcagggtat
      181 taataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002021             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23382:14080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002021
VERSION     KCVT01002021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23382:14080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79546.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccacg gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002022             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14039:12436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002022
VERSION     KCVT01002022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14039:12436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..359
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79547.1"
                     /translation="CQQYDSDSLTF"
     J_segment       364..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           98 a          110 c          104 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctaggactcc tgctgctctg
       61 tctcccaggt gccaaatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtcacca tcacttgtcg ggcgactcag gacattcgca gttatttagc
      181 gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg cgtccacttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt atgacagtga
      361 ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002023             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13709:15562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002023
VERSION     KCVT01002023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13709:15562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79548.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          119 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gtacctccag aagccaggcc
      241 agtctccacg cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggac ttattactgc atccaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002024             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21675:5479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002024
VERSION     KCVT01002024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21675:5479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..438
                     /note="immunoglobulin light chain variable region"
     V_region        103..438
     V_segment       103..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79549.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cgttgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002025             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19044:10275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002025
VERSION     KCVT01002025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19044:10275"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79550.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac cacgtaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002026             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12777:14964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002026
VERSION     KCVT01002026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12777:14964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..381
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79551.1"
                     /translation="CQQGNSIPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          114 c          106 g           96 t
ORIGIN      
        1 acatgggggc ctgtgacagg gctcagctaa cataatggat tttcaggctc aaattttcat
       61 cttccttctg ctcagtgtca cagtgtccaa tggagaaatt gtgctgaccc agtctccaac
      121 atccatggct gtctcccaag gagaaagagt caccatctcc tgcacggcca gttcaagtgt
      181 aagcaccagc tacctgcact ggtaccaaca gaagccagga ttccctccaa ggcttcttgt
      241 ccatagaaca tcaagtctgg cttctggggt cccagccagg ttcagtggca gcggttctgg
      301 gacctcttac acgctcacaa tcagcagcat ggaggctgaa gatgctgcaa actattactg
      361 tcagcagggg aatagcattc cgctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002027             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17616:14184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002027
VERSION     KCVT01002027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17616:14184"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..406
                     /note="immunoglobulin light chain variable region"
     V_region        70..406
     V_segment       70..368
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79552.1"
                     /translation="CGQAIAFPLTF"
     J_segment       369..406
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>409
                     /gene="IGKC"
BASE COUNT           86 a          112 c          116 g           95 t
ORIGIN      
        1 acatgggcaa tgaggctccc tgctcagttc ctggggctgc tgatgctctg gctccctgga
       61 tccagtgggg atattgtgat gacccagact ccactctccc tgcccatcac ccctggagag
      121 ccggcctcca tctcctgcag gtctagtcag agcctcctgc atactaatgg taacacctat
      181 ttgcactggt acctacagaa gccaggccag tctccgcagc tcctgattta tgggggttcc
      241 aacagagcct ctggagtccc agacaggttc agtggcagtg ggtcaggcac tgatttcaca
      301 ctgaaaatcg acaaggtgga ggcggaggat gttggggttt attactgcgg tcaagctata
      361 gcgtttccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002028             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24568:13872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002028
VERSION     KCVT01002028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24568:13872"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79553.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          123 g           96 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagagaggat ggaaacacct atttggactg gtacctgcag aggccaggcc
      241 agactcccca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atcttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002029             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:23312:9573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002029
VERSION     KCVT01002029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23312:9573"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79554.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtac tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc attttctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002030             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:5760:15155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002030
VERSION     KCVT01002030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5760:15155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79555.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagac ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002031             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12614:5171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002031
VERSION     KCVT01002031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12614:5171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79556.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc aacggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002032             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:25151:19135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002032
VERSION     KCVT01002032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25151:19135"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79557.1"
                     /translation="CQQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          112 a          111 c          101 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 gggactcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cactagtatt tatttaaatt ggtatcaaca aaaaccgggg aaagccccta agctcctgat
      241 ctattatgga aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcaacagcct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtacacttt tggccacggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002033             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14353:4885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002033
VERSION     KCVT01002033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14353:4885"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79558.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          123 c          121 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccgcaact cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01002034             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13457:14570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002034
VERSION     KCVT01002034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13457:14570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..375
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79559.1"
                     /translation="CQQGYTYLYSF"
     J_segment       383..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          106 g          101 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgttggagac acagtcacca tcacttgcca ggcgagtcaa
      181 gccattgcca ataatttaaa ttggtatcag cagaaaccag gaaaagcccc taaagtcctg
      241 atctataggg catccagttt gcaaagtggg tttccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatactta cttgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002035             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7433:12270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002035
VERSION     KCVT01002035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7433:12270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79560.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002036             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6149:14809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002036
VERSION     KCVT01002036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6149:14809"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79561.1"
                     /translation="CQQYSSDPYNF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          114 c          106 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 acattagaag ttatttagcg tggtatcagc agaaaccagg aaaagccccg aaggccttga
      241 tctattacgc atccatttta gagagtgcgg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcgcc atcagcagcc tgcagtctga cgattttgca acttattact
      361 gtcaacaata tagcagtgac ccgtacaatt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002037             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24396:15457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002037
VERSION     KCVT01002037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24396:15457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79562.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          117 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcaccttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01002038             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17012:9983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002038
VERSION     KCVT01002038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17012:9983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79563.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          114 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002039             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16263:23523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002039
VERSION     KCVT01002039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16263:23523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79564.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaagttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002040             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18788:15968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002040
VERSION     KCVT01002040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18788:15968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79565.1"
                     /translation="CEQYNSLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          113 c          104 g           97 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaac gtttatttaa attggtatca ccagaaaccg gggaaagccc ctaagctcct
      241 gatctattat acaaaccgtt tggaaactgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ctgtgaacaa tacaatagtt taccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002041             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:9113:6989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002041
VERSION     KCVT01002041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9113:6989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79566.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctccttc tgtcggagac agagtcacca tcacttgccg ggcaagtcag
      181 gtcattagga gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taaactcctg
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagactttgg aacttattac
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002042             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13738:18627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002042
VERSION     KCVT01002042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13738:18627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79567.1"
                     /translation="CEQYNSLPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          112 c          105 g           97 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacgttaa catttattta aattggtatc accagaaacc ggggaaagcc cctaagctcc
      241 tgatctatta tacaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtgaaca atacaatagt ttaccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002043             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13503:11615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002043
VERSION     KCVT01002043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13503:11615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79568.1"
                     /translation="CQQYDSDPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag tgtggtatca gcagaaacca gggaaagtcc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgctcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01002044             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:26929:15594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002044
VERSION     KCVT01002044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26929:15594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79569.1"
                     /translation="CQHSFRTPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct atctgcatct gtaggagaca gagtcaatgt cacttgcagg gctagtgaga
      181 gcgttagcac caaattacat tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc gtccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gaacagattt cactctcacc atcagcagcc tgcagcctga agatgtcgca actttttact
      361 gtcagcatag ttttcgtacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002045             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:7938:12462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002045
VERSION     KCVT01002045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7938:12462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79570.1"
                     /translation="CLQYKSFPYTF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          110 a          116 c           94 g           97 t
ORIGIN      
        1 acatggggac acagtcagga cacagcatgg acatgagggc ccccgctcat ctcctagggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgactcag tctccatctt
      121 ccctgtctgc atctgtggga gacactgtca ccatcacttg ccggacaagt caaggtatta
      181 ccaattattt acattggttt caacagaaac cagggaaagc ccctaaactc ctgatctatg
      241 aaacatccag tttgacaagt ggggtcccat caaggttcag cggcagcgca tctgggacag
      301 aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtctac
      361 agtataaaag tttcccgtac acttttggcc aggggaccaa actggagatc aaacgag
//
LOCUS       KCVT01002046             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5275:4506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002046
VERSION     KCVT01002046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5275:4506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79571.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgctt gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatctggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002047             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17764:8911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002047
VERSION     KCVT01002047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17764:8911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79572.1"
                     /translation="CMQPLEFLWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttct gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002048             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18681:16327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002048
VERSION     KCVT01002048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18681:16327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79573.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          120 c          122 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaggcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002049             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11098:12233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002049
VERSION     KCVT01002049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11098:12233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79574.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcgagtcaga
      181 gcctcttgga tggtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002050             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10398:10389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002050
VERSION     KCVT01002050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10398:10389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79575.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          124 c          117 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc gggtctagtc
      181 agaggctctt ggatagtgag gatgagaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01002051             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10593:12678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002051
VERSION     KCVT01002051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10593:12678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79576.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatactga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaaaaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002052             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20482:8848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002052
VERSION     KCVT01002052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20482:8848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79577.1"
                     /translation="CQQGYGFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          118 c          103 g          103 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catccttcct gtccgcatct gtaggagaca cagtcgcgat cacttgcctg gcgagtcaag
      181 gcattggcaa taatttaaat tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctatacggc atccaattta catggtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcaacagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatggtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002053             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14434:5818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002053
VERSION     KCVT01002053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14434:5818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79578.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01002054             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19632:7451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002054
VERSION     KCVT01002054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19632:7451"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79579.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          122 c          119 g           86 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg ctcccaggct
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcagttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002055             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20492:14850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002055
VERSION     KCVT01002055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20492:14850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79580.1"
                     /translation="CMQALEFPLTF"
     J_segment       312..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           79 a           89 c          101 g           83 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccgctctccc tgcccgtcat ccttggagag
       61 ccggcctccc tatcctgcac gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggatt ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagtttc cgctcacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002056             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13291:6957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002056
VERSION     KCVT01002056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13291:6957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    49..370
                     /note="immunoglobulin light chain variable region"
     V_region        49..370
     V_segment       49..318
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <310..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79581.1"
                     /translation="CLQGDTAPFTF"
     J_segment       335..370
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>373
                     /gene="IGKC"
BASE COUNT           88 a           99 c           98 g           88 t
ORIGIN      
        1 acatgggtcc tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg
       61 acccagtctc catcttccct gtctgcatcg gcaggagaca gagtcaccat cacttgccgg
      121 gcaagtcagg gcattaacga ttatttaagt tggtatcagc agaaaccagg aaaacctcct
      181 aagcgcctga tttatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc
      241 agtggatctg ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca
      301 gcttattact gtctacaggg tgatactgcc ccgttcactt tcggcggagg gaccaaggtg
      361 gagatcaaac gag
//
LOCUS       KCVT01002057             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18549:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002057
VERSION     KCVT01002057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18549:10474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79582.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctcatgctct ggctccctgt atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atgtcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc ggtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 tgatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002058             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:28706:14424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002058
VERSION     KCVT01002058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:28706:14424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79583.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtgggttccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002059             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:4666:7178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002059
VERSION     KCVT01002059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4666:7178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..436
                     /note="immunoglobulin light chain variable region"
     V_region        101..436
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79584.1"
                     /translation="CMQALEFPRTF"
     J_segment       405..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>443
                     /gene="IGKC"
BASE COUNT           95 a          124 c          119 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgt atccagtggt gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgcgg atggaaacac ctatttggac tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ctccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtggctcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 agatgttggg atttattact gcatgcaagc tctagagttt cctcggacgt tcggccaggg
      421 gaccaaggtg gaaatcgaac gag
//
LOCUS       KCVT01002060             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15255:13949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002060
VERSION     KCVT01002060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15255:13949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79585.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002061             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20572:5814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002061
VERSION     KCVT01002061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20572:5814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79586.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          102 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctaatcta
      241 taaggcatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcgccctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002062             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13793:7376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002062
VERSION     KCVT01002062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13793:7376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79587.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcatc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002063             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14343:22459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002063
VERSION     KCVT01002063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14343:22459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79588.1"
                     /translation="CMQSLEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          116 c          122 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgg ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctctagagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaatctcta gagtttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01002064             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11265:11737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002064
VERSION     KCVT01002064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11265:11737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79589.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          127 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002065             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9690:4335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002065
VERSION     KCVT01002065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9690:4335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79590.1"
                     /translation="CQHSFRTPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          115 c          108 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caatgtcact tgcagggcta gtgagagcgt
      181 tagcaccaaa ttacattggt atcagcagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctggaac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gtcgcaactt tttactgtca
      361 gcatagtttt cgtaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002066             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15851:7569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002066
VERSION     KCVT01002066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15851:7569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79591.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          127 c          111 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggacatcaa
      421 acgag
//
LOCUS       KCVT01002067             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13192:15128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002067
VERSION     KCVT01002067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13192:15128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79592.1"
                     /translation="CMQALDFPWTF"
     J_segment       313..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           83 a           89 c           99 g           81 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagactttc cttggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002068             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9163:3759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002068
VERSION     KCVT01002068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9163:3759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79593.1"
                     /translation="CQQNDNWARTF"
     J_segment       391..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          105 a          122 c          119 g           83 t
ORIGIN      
        1 acatggggga ggaggaactg ctcagttagg acccagaggg aaccatggaa gccccagcac
       61 agcttctctt cctcctgctg ctctggctcc cagacaccac cggagaaata gtgatgacgc
      121 agtctccagc caccctgtcc ttgtctccag gagaaagagc caccctctcc tgtagggcca
      181 gtcagagtgt cagcagcagt ttagcctggt accagcagaa acctggacag gctcccaggc
      241 tcctcatcta tggtgcatcc aacagggcca ctggcatccc agacaggttc agtggcagtg
      301 ggtctgggac agagttcact ctcaccatca gcagcctgga gcctgaagat gttgcagttt
      361 attattgtca gcagaatgat aactgggctc ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01002069             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:23699:13111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002069
VERSION     KCVT01002069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:23699:13111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79594.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcgga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002070             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15738:11794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002070
VERSION     KCVT01002070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15738:11794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79595.1"
                     /translation="CLQFKTFPYSF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          118 c          108 g          105 t
ORIGIN      
        1 acatggggtt gcaggagtca gacacagtca ggacacagca tggacatgag ggcccccgct
       61 catctcctag ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact
      121 cagtctccat cttccctgtc tgcatctgta ggagacactg tcaccatctc ttgccgggca
      181 agtcagggta ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctaag
      241 ctcctcatct atgctgcatc cactttggcc ggtggggtcc catcaaggtt cagcggcagt
      301 ggatctggga cagacttcac tttcaccatc agcagcctgc agcctgaaga ttttgcaact
      361 tattactgtc tacagtttaa aactttcccg tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01002071             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14999:15389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002071
VERSION     KCVT01002071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14999:15389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79596.1"
                     /translation="CQQYNSLPFTF"
     J_segment       383..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          106 a          114 c          101 g          102 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cgcttgccgg gcaagtcagg
      181 acattggcta ttttttaaat tggtatcaac agaaaccggg aaaagcccct aagctcctac
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccattcactt ttggccccgg gaccaaactg gatatcagac
      421 gag
//
LOCUS       KCVT01002072             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15593:4104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002072
VERSION     KCVT01002072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15593:4104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79597.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaag tctagtcaga
      181 gcctcttgga tagtggagat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002073             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16115:6049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002073
VERSION     KCVT01002073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16115:6049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..396
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79598.1"
                     /translation="CQQHNGYPPTF"
     J_segment       409..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          113 a          124 c          113 g           96 t
ORIGIN      
        1 acatggggag gctggtcaca cttcatgtag gagtcagaac cactcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acacagtcac
      181 catcacttgt cgggcaagtc agggcattac gaatgattta gcctggtatc aacagaaacc
      241 aggtaaagcc ccgaagcccc tgatctatta cgcatccaat ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga tttcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt attgtcaaca gcataatgga taccctccga cgttcggcca
      421 agggaccagg gtggaaatca aacgag
//
LOCUS       KCVT01002074             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19987:20139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002074
VERSION     KCVT01002074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19987:20139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79599.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          117 c          106 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaggc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002075             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15019:12323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002075
VERSION     KCVT01002075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15019:12323"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79600.1"
                     /translation="CIQGLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          118 c          118 g          108 t
ORIGIN      
        1 actgggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagtc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgacgatg gaaataccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcacaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tacaaggtct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002076             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:25085:17296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002076
VERSION     KCVT01002076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25085:17296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79601.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tctagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002077             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:7131:3366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002077
VERSION     KCVT01002077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:7131:3366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79602.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          118 c          118 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggctc cagtggggac attgtgatga cccagactcc
      121 attctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtgtcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002078             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24876:4964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002078
VERSION     KCVT01002078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24876:4964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..368
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79603.1"
                     /translation="CHQTYNYPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          119 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca ataatttaaa ttggtatctc cagaaaccag ggaaagcccc taaactcctg
      241 atctataggg catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggact tcactctcag catcagcagc ctgcagcctg aagattttgc cacttattcc
      361 tgtcaccaga cgtataatta cccgtggacg ttcggccatg ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002079             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12018:14296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002079
VERSION     KCVT01002079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12018:14296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..328
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79604.1"
                     /translation="CQQYNSLPLSF"
     J_segment       329..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           95 a           91 c           91 g           92 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc
       61 agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa
      121 gtcagggcat tagtgtttat ttaaattggt atcagcagaa accggggaaa gcccctaaac
      181 tcctgatcta ttatgcaaac cgtttagaaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca acttgaagat tttgcaactt
      301 attactgtca acaatataat agtttaccgc tctctttcgg tggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01002080             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:12115:8510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002080
VERSION     KCVT01002080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12115:8510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    202..467
                     /note="immunoglobulin light chain variable region"
     V_region        202..467
     V_segment       202..429
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <407..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79605.1"
                     /translation="CMQPLEFPWTF"
     J_segment       430..467
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>470
                     /gene="IGKC"
BASE COUNT          108 a          126 c          130 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc aagagcttca acagaggaga gtgttagagg gagaagtgcc
      181 ccgggccccc cacttgctcc ttagccccag cctcttggat agtgaggatg gaaacactta
      241 tttggaatgg tacctgcaga agccaggcca gtctccacag ctcttgattt atgaggtttc
      301 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac
      361 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca tgcaacctct
      421 agagtttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01002081             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20244:8581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002081
VERSION     KCVT01002081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20244:8581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79606.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagtcaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002082             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19825:14361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002082
VERSION     KCVT01002082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19825:14361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79607.1"
                     /translation="CQHSFDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          106 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gtccctgagc tcctgatcta
      241 tgctgcatcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg ggtctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcacagtttt gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002083             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13776:4728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002083
VERSION     KCVT01002083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13776:4728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79608.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccaac aaaaacctgg gcaggctccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagactt cactctcacc atcaccagcc tggagcctga agatgttgca gtttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002084             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:9917:12132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002084
VERSION     KCVT01002084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9917:12132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79609.1"
                     /translation="CQQYDSDTRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           91 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgaca cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002085             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7098:10405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002085
VERSION     KCVT01002085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7098:10405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..432
                     /note="immunoglobulin light chain variable region"
     V_region        97..432
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79610.1"
                     /translation="CMQALEFPRTF"
     J_segment       401..432
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>439
                     /gene="IGKC"
BASE COUNT           94 a          122 c          119 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctgtatcc agtggtgaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagt
      181 ctcttggata gtgcggatgg aaacacctat ttggactggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtctcc gaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg gctcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaagat
      361 gttgggattt attactgcat gcaagctcta gagtttcctc ggacgttcgg ccaggggacc
      421 aaggtggaaa tcgaacgag
//
LOCUS       KCVT01002086             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20360:16337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002086
VERSION     KCVT01002086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20360:16337"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79611.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctttgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002087             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13076:19301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002087
VERSION     KCVT01002087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13076:19301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..348
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79612.1"
                     /translation="CQQHADSPRTF"
     J_segment       350..385
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           97 a          111 c           96 g           84 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctgggg ctcctgttgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gcacagccag ccacgatata aataattggt tggcctggta tcaacagaaa
      181 ccaggaaaag cccctaacct cctgatctat agggcatcca atttggaaac aggggtccca
      241 tcgaggttca gtggaagtgg atctgggaca gatttcactc tcaccatcag cagcctgcag
      301 cctgaagatt tcgcaacata ttactgtcaa cagcatgctg attcccctcg gacgttcggc
      361 caagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002088             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14943:8864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002088
VERSION     KCVT01002088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14943:8864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79613.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002089             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9932:11908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002089
VERSION     KCVT01002089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9932:11908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79614.1"
                     /translation="CQHSYNTPYSF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          102 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 cattctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtcaga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctatgctgc atccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatgttgca acttattact
      361 gtcagcatag ttataatacc ccctacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002090             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21526:12707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002090
VERSION     KCVT01002090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21526:12707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79615.1"
                     /translation="CQRYSYSTWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          120 c          116 g           91 t
ORIGIN      
        1 acatggggga gaagagctgc tcagttagga cccagagaga accatggaaa tcccagctca
       61 gcttctcttc ctcctgctac tgtggctccc aggtaccacc ggacaagtta tattgactca
      121 gtctccagcc accctgtctt tgtctccagg ggaaagagcc accctctcct gcagggccag
      181 tcagagtatt ggcagcagct tagtttggta ccagcagaaa cctgggcagg cccccaggct
      241 cctcatctat ggtgcatcca gcagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatt ttgcagtgta
      361 ttactgtcag aggtatagtt actccacgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01002091             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15590:18231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002091
VERSION     KCVT01002091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15590:18231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79616.1"
                     /translation="CLQGYIIPYNF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          110 c          112 g          100 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttggaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 attgtctaca gggttatatt atcccgtaca attttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002092             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16762:3855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002092
VERSION     KCVT01002092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16762:3855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79617.1"
                     /translation="CMQAREFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          116 c          121 g          107 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga gactccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcactct tggagagccg gcctccatct cctgcatgtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat gtggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc tacctggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcga gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01002093             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15631:5870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002093
VERSION     KCVT01002093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15631:5870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79618.1"
                     /translation="CQQHDNSPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 cttcctccct gtctgcatct ataggcgaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattagcga ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atccaatttg gagacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcaggctga agatttcgca acatatttct
      361 gtcaacagca tgataattcc cctcccactt tcggtggagg gactaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002094             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16541:18301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002094
VERSION     KCVT01002094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16541:18301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..383
                     /note="immunoglobulin light chain variable region"
     V_region        44..383
     V_segment       44..346
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79619.1"
                     /translation="CMQSLEIPPTF"
     J_segment       349..383
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           85 a           99 c          110 g           92 t
ORIGIN      
        1 acatggggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
       61 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      121 tcagagcctc ttggatagtg gggatggaaa cacctatttg gattggtacc tgcagaagcc
      181 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      241 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      301 tgaggatgtt ggggtttatt actgcatgca atctctagag attcctccca ctttcggtgg
      361 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01002095             385 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12640:6014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002095
VERSION     KCVT01002095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 385)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12640:6014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..380
                     /note="immunoglobulin light chain variable region"
     V_region        100..380
     V_segment       100..339
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <322..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79620.1"
                     /translation="CQQSYRYPLTF"
     J_segment       345..380
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>385
                     /gene="IGKC"
BASE COUNT           88 a          106 c          101 g           90 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ctggtatctt gcatccactt tgcagagtgg ggtcccatca
      241 aggttcagcg gcagtggatc tgggacagat ttcactctcg ccatcagcag cctgcagcct
      301 gaagatgctg caacttatta ctgtcagcag agttatcgtt atccgctcac tttcggtgga
      361 gggacccagg tggaaatcaa tcgag
//
LOCUS       KCVT01002096             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17545:15558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002096
VERSION     KCVT01002096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17545:15558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79621.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002097             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21068:15429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002097
VERSION     KCVT01002097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21068:15429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79622.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccatac gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagtag agtggaggct
      361 gaggatgttg ggatttatta ctgcatgcaa gctctagagt ttcctctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002098             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10317:6148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002098
VERSION     KCVT01002098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10317:6148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79623.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagcgc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggtaacacct atttggaatg gttcctccag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002099             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8801:14120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002099
VERSION     KCVT01002099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8801:14120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79624.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcctgggtc cagtggggac attgtgttga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcatag
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002100             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15462:20505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002100
VERSION     KCVT01002100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15462:20505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79625.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          119 c          104 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaacataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002101             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19813:13690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002101
VERSION     KCVT01002101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19813:13690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79626.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaag tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002102             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:27378:11084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002102
VERSION     KCVT01002102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:27378:11084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..364
                     /note="immunoglobulin light chain variable region"
     V_region        87..364
     V_segment       87..326
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79627.1"
                     /translation="CQQYNSGPFTF"
     J_segment       327..364
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           97 a           99 c           91 g           80 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccagga gacagagtaa ccatcacttg tcgggcgagt
      121 caggacataa gaagttattt agcgtggtat cagcagaaac cagccaaagc cccgaagccc
      181 ttgatctatt acgcatccgt tttggaaagt ggggtcccat caaggttcag tgccagtgga
      241 tctgggacag aattcactct caccatcagc agtctgcagc ctgaagattt tgcaacttat
      301 tactgtcaac agtataacag tggcccattc actttcggcc ccgggaccaa actggatatc
      361 aaacgag
//
LOCUS       KCVT01002103             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13292:8342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002103
VERSION     KCVT01002103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13292:8342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79628.1"
                     /translation="CQQYNSEPRTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          116 c          113 g           92 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaact agggaaaccc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gagccgcgca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002104             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20666:10536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002104
VERSION     KCVT01002104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20666:10536"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79629.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          103 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01002105             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17759:13098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002105
VERSION     KCVT01002105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17759:13098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79630.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          112 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aaggcattga
      241 tctattacgc gtccactttg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccagggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002106             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6622:11683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002106
VERSION     KCVT01002106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6622:11683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79631.1"
                     /translation="CMQPLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcattg gtacctgaag aagccaggcc
      241 agtctccaca gttcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002107             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20252:10868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002107
VERSION     KCVT01002107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20252:10868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79632.1"
                     /translation="CLQYKTYPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          104 a          110 c          105 g           99 t
ORIGIN      
        1 acatggggga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg cttctgtagg agacactgtc accatcactt gccgggcaag tcagggtatt
      181 gctggttatt taaattggtt tcagaagaaa ccagggaaag cccctaagct cctgatccaa
      241 gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa cttatccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01002108             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:10590:10562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002108
VERSION     KCVT01002108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10590:10562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79633.1"
                     /translation="CMQSIKDPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          100 a          121 c          112 g          106 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcat cttctcacga tgggactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tccagtgggg atattgtgat gacccagacc
      121 ccactctcgg tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctcc atagtaatgg agacacctat ttacattggt accttcagag gtcaggccag
      241 tctccacggc tcctgatcta taaagtaacc aatcggctac ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 attggtgttt atttctgcat gcaaagtata aaagatccat tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01002109             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22546:17891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002109
VERSION     KCVT01002109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22546:17891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..429
                     /note="immunoglobulin light chain variable region"
     V_region        98..429
     V_segment       98..393
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79634.1"
                     /translation="CLQSKNSPWTF"
     J_segment       394..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>434
                     /gene="IGKC"
BASE COUNT           99 a          117 c          117 g          101 t
ORIGIN      
        1 acatggggag gagcagcctc tagttcagct ctcagaaatg gggtcctggg ctcctttcct
       61 gtggatcctc ctgctctgtg ctccaggctg caatggggac attgtgctga cccagtctcc
      121 agcctctttg gccgtgtctc cagggcagag ggccaccatc acctgcagag ccagtgagag
      181 tgtcagtttg tttggaatca gcctcattca ctggtatcag cagaaaccag gacaacctcc
      241 taaactcctg atttaccaag cattcaacac agagactggg gtcccagtca ggttcagcgg
      301 cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaacctg acgatgctgc
      361 agattattac tgtctgcaga gtaagaattc tccgtggacg ttcggccaag ggaccaaggt
      421 ggaaatcaag cgag
//
LOCUS       KCVT01002110             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12783:14853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002110
VERSION     KCVT01002110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12783:14853"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79635.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          124 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga aggtgaggat ggaaacacct acttggaatg gtatatgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002111             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14125:5071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002111
VERSION     KCVT01002111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14125:5071"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79636.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tcggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002112             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12736:11456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002112
VERSION     KCVT01002112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12736:11456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79637.1"
                     /translation="CMQALDFPYSF"
     J_segment       399..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          106 t
ORIGIN      
        1 acatggggga cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagcc
      181 tcttggatag tgaggatgga aacacctatt tggaatggta cctacagaag ccaggccagt
      241 ctccacagct cttgattttt gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact aatttcacac tgaaaatcag cagtgtggag gctgaggatg
      361 ttggggtcta ttactgcatg caagctctag actttcctta cagttttggc caggggacca
      421 cagtggagat taaacgag
//
LOCUS       KCVT01002113             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12677:11238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002113
VERSION     KCVT01002113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12677:11238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79638.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002114             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18278:9977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002114
VERSION     KCVT01002114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18278:9977"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..389
                     /note="immunoglobulin light chain variable region"
     V_region        126..389
     V_segment       126..351
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79639.1"
                     /translation="CQQYNSDPYTF"
     J_segment       352..389
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>392
                     /gene="IGKC"
BASE COUNT           99 a          106 c          100 g           87 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccaggtga cccagtctcc
      121 atcctccatc acttgtcggg cgagtcaggg cattagaagt tatttagcgt ggtatcagct
      181 gagaccaggg aaagccccga aggccttaat ctattacgcg accattttgg aaagtggggt
      241 cccatcaagg ttcaccggca gtggatctgg gacagaattc actctcacca tcagcagcct
      301 gcagcctgag gattttgcaa cttatttctg tcaacaatat aacagtgacc cgtacacttt
      361 tggccagggg accaaagtag agatcaaacg ag
//
LOCUS       KCVT01002115             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17245:7888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002115
VERSION     KCVT01002115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17245:7888"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79640.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggcttcct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002116             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19568:18613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002116
VERSION     KCVT01002116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19568:18613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79641.1"
                     /translation="CQQYNSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          114 c          106 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc agaaaccagg aaaagccccg aaggccttga
      241 tctattacgc atccatttta gaaagtgcgg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga cgattttgca acttattact
      361 gtcaacagta taacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002117             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21330:7983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002117
VERSION     KCVT01002117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21330:7983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79642.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtcttcacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagttccct tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002118             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18805:6393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002118
VERSION     KCVT01002118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18805:6393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..317
                     /note="immunoglobulin light chain variable region"
     V_region        107..317
     V_segment       107..280
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <257..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79643.1"
                     /translation="CQQHDDSPRTF"
     J_segment       282..317
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>320
                     /gene="IGKC"
BASE COUNT           84 a           87 c           87 g           62 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga aaccaggaaa
      121 agcccctaaa ctcctgatct atagggcatc caatttggaa acaggggtcc catcgaggtt
      181 cggtggaagt ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga
      241 tatcgcaaca tattactgtc aacagcatga tgattcccct cggacgttcg gccaagggac
      301 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002119             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22755:17642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002119
VERSION     KCVT01002119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22755:17642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79644.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002120             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16518:12892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002120
VERSION     KCVT01002120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16518:12892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79645.1"
                     /translation="CQQGNSIPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          113 c          105 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccattact tgccgggcaa gtcagggcat
      181 taccaattat ttaaattggt atcagcagaa accggggaaa gccccaaagg tcctgatcta
      241 ttatgcagac agtttgtcaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagggtaat agtattccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01002121             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9412:5259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002121
VERSION     KCVT01002121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9412:5259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..440
                     /note="immunoglobulin light chain variable region"
     V_region        119..440
     V_segment       119..403
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79646.1"
                     /translation="CQQNSNWPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          104 a          125 c          125 g           89 t
ORIGIN      
        1 acatgggggg ggtcagagct ctggggagga actgctcagt taggacccag agggaaccat
       61 ggaagcccca gcacagcttc tcttcctcct gctgctctgg ctcccagata ccaccggaga
      121 aatagtgatg acgcagtctc cagccaccct gtctttgtct ccaggagaaa gagccaccct
      181 ctcctgcagg gccagtcaga gtgtcagcag cagcttagcc tggtaccagc agaaacctgg
      241 gcaggctccc agactcctca tctatggtgc atccaacagg gccactggca tcccagacag
      301 gttcagtggc agtgggtctg ggacagagtt cactctcacc atcagcagcc tggagcctga
      361 agatgttgca gtttattatt gtcagcagaa tagtaactgg cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002122             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7058:15923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002122
VERSION     KCVT01002122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7058:15923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79647.1"
                     /translation="CQQYNSDPRTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          118 c          114 g           91 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtataaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002123             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19509:4572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002123
VERSION     KCVT01002123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19509:4572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..329
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79648.1"
                     /translation="CQQGNSNPLTF"
     J_segment       330..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           95 a           93 c           94 g           87 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc
       61 agtttccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa
      121 gtcaggccat tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac
      181 tcctgatata ctatggaaaa agtttggcaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt
      301 attactgtca acagggtaat agtaatcctc tcactttcgg cggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01002124             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:25699:13141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002124
VERSION     KCVT01002124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25699:13141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79649.1"
                     /translation="CQQYDSLPYSF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca cagtcaccat tacttgccgg gcaagtcagg
      181 gcattaacag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agcggatctg
      301 ggacagaatt cactctcacc atcagtggcc tgcaacctga cgattttgca acttattact
      361 gtcaacagta tgatagttta ccatacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002125             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23336:6732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002125
VERSION     KCVT01002125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23336:6732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79650.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          106 c          108 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gtatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagtttt ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatgcaaac cgtttggaaa gaggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gtagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002126             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7139:9375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002126
VERSION     KCVT01002126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7139:9375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79651.1"
                     /translation="CQQYNRFPLTF"
     J_segment       384..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          107 a          111 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagtaa ttacttaaat tggtatcagc aaaagccggg gaaagcccca aagcccctga
      241 tctattatgt aaaccgtttg gaaaatggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca atttattact
      361 gtcaacaata taataggttt cctctcactt tcggtggggg gaccaaggtg gagatcagac
      421 gag
//
LOCUS       KCVT01002127             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8523:6426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002127
VERSION     KCVT01002127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8523:6426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79652.1"
                     /translation="CMQAREFPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           99 a          127 c          117 g          102 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 attccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tcgatagtga ggaggggaac acctatttgg aatggtacct acagaagcca
      241 ggccagtctc cacaactctt gatttatgag gtctccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgctg gggtttatta ctgcatgcaa gctcgagagt ttccattcac tttcggcccc
      421 gggaccaaac tggacatcaa acgag
//
LOCUS       KCVT01002128             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7816:5270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002128
VERSION     KCVT01002128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7816:5270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79653.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaacctggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002129             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:26294:15385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002129
VERSION     KCVT01002129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26294:15385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79654.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 gacgag
//
LOCUS       KCVT01002130             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12996:14011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002130
VERSION     KCVT01002130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12996:14011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79655.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagaagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002131             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10508:18066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002131
VERSION     KCVT01002131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10508:18066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..282
                     /note="immunoglobulin light chain variable region"
     V_region        6..282
     V_segment       6..244
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79656.1"
                     /translation="CLQYKSFPYSF"
     J_segment       245..282
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>285
                     /gene="IGKC"
BASE COUNT           83 a           68 c           64 g           70 t
ORIGIN      
        1 acatgggaga cactgtcacc atcacttgcc ggacaagtca aggtattacc aattatttac
       61 attggtttca gcagaaacca gggaaagccc ctaagctcct gatctatgaa acatccagtt
      121 tggtaagtgg ggtcccatca aggttcagcg gcagtgcatc tgggacagaa ttcactctca
      181 ccatcagcag cctacagcct gaagattttg catcttatta ctgtctacag tataaaagtt
      241 tcccgtacag ttttggccag gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01002132             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:4264:11883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002132
VERSION     KCVT01002132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:4264:11883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79657.1"
                     /translation="CQQHDNAPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          114 g           84 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagatct cactctcagc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcagcagca tgacaatgcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002133             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18192:2689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002133
VERSION     KCVT01002133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18192:2689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    135..398
                     /note="immunoglobulin light chain variable region"
     V_region        135..398
     V_segment       135..360
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <338..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79658.1"
                     /translation="CMQPLEFPWTF"
     J_segment       361..398
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>401
                     /gene="IGKC"
BASE COUNT           92 a          104 c          112 g           93 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcaga gcctcttgga tagtgaggat ggaaacacct atttggaatg
      181 gtacctgcag aagccaggcc agtctccaca gctcttgatt tatgaggttt ccaaccgggc
      241 ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca cactgaaaat
      301 cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaacctc tagagtttcc
      361 gtggacgttc ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002134             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:12369:9988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002134
VERSION     KCVT01002134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12369:9988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79659.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atacaaccgg acaaatagtg ctgacgcagt
      121 ctccagacac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002135             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20228:7921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002135
VERSION     KCVT01002135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20228:7921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79660.1"
                     /translation="CQQVYGNPIFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          115 c          105 g          105 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccagatg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag taatttagcg tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctatgctgc atcgaaattg caaggtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattctgcc acttattact
      361 gtcaacaggt ttatggtaat cctatattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01002136             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19502:16982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002136
VERSION     KCVT01002136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19502:16982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79661.1"
                     /translation="CQQHNTYPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcactagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatactta cccgtacact tttggccagg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002137             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20434:20398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002137
VERSION     KCVT01002137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20434:20398"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79662.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccggtc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002138             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20633:19532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002138
VERSION     KCVT01002138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20633:19532"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79663.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagactg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002139             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21872:7376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002139
VERSION     KCVT01002139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21872:7376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79664.1"
                     /translation="CQQYNSLPYTF"
     J_segment       385..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          107 a          114 c          103 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattgcctat tttttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctgat
      241 ctattatgca aaccgcttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcaacagcct acaacctgaa gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cttacacttt cggcggaggg accaagatgg agatcaaccg
      421 ag
//
LOCUS       KCVT01002140             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20178:12085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002140
VERSION     KCVT01002140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20178:12085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79665.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          125 c          114 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacgtgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat cagcagagtg gaggctgagg
      361 atcttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002141             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21268:12284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002141
VERSION     KCVT01002141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21268:12284"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79666.1"
                     /translation="CLQGYNIPYNF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          110 c          110 g           98 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagttg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccagg aaaagctcct aagcgcctga
      241 tctatgctgt gtccagtttg gaaggtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg ttataatatc ccgtacaatt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002142             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16406:12243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002142
VERSION     KCVT01002142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16406:12243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79667.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctactacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002143             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12156:15321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002143
VERSION     KCVT01002143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12156:15321"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..370
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79668.1"
                     /translation="CQQVLTNPAF"
     J_segment       387..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          112 c          108 g          100 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ctgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gatatccagg tgacccagtc
      121 tccatctgcc ttgtctgcat ctgtaggaga cagagtcacc atctcttgcc gggcaagtca
      181 gaacatttat aggaatttag cgtggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatctatgct gcatccagat tgcaaagtgg gtttccctct cggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcaa cctacagcct gaagattctg caatttatta
      361 ctgtcaacag gttcttacta atccggcgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002144             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10559:15669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002144
VERSION     KCVT01002144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10559:15669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79669.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga cggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002145             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18039:17982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002145
VERSION     KCVT01002145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18039:17982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79670.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002146             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15397:17927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002146
VERSION     KCVT01002146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15397:17927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..271
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <249..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79671.1"
                     /translation="CMQALEFPWTF"
     J_segment       272..309
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>312
                     /gene="IGKC"
BASE COUNT           76 a           76 c           90 g           70 t
ORIGIN      
        1 acatgggcac ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg
       61 atagtgagga tggaaacacc tatttggaat ggcacctgca gaagccaggc cagtctccac
      121 agctcttgat ttatgaggtt tccaaccggg cctccggagt cccagacagg ttcagtggct
      181 ctgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa gatgttgggg
      241 tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg accaaggtgg
      301 aaatcaaacg ag
//
LOCUS       KCVT01002147             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13650:18749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002147
VERSION     KCVT01002147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13650:18749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79672.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          121 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctccc tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002148             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17172:10348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002148
VERSION     KCVT01002148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17172:10348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79673.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          122 c          119 g           94 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tttctgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacgctgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01002149             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12988:9688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002149
VERSION     KCVT01002149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12988:9688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79674.1"
                     /translation="CMQPLDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagactttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002150             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24055:13154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002150
VERSION     KCVT01002150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24055:13154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79675.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaatacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atccaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtaga aatcaaacga g
//
LOCUS       KCVT01002151             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:4689:12452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002151
VERSION     KCVT01002151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4689:12452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79676.1"
                     /translation="CQQYSSLPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          109 c          110 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacaa tcacttgccg ggcaagtcag
      181 ggcattagca attatttaaa ttggtatcag cagaaaccgg ggaaagcccc taaggtcctg
      241 atgtattata caaaccgctt ggaaagtggg atcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctggaacctg atgattttgc aacttattac
      361 tgtcaacagt atagttcttt accgtggacg ttcggccaag ggaccaaggt ggaattcaaa
      421 cgag
//
LOCUS       KCVT01002152             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10805:11773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002152
VERSION     KCVT01002152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10805:11773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79677.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtggg gatcaaacga g
//
LOCUS       KCVT01002153             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6516:2832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002153
VERSION     KCVT01002153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6516:2832"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79678.1"
                     /translation="CMQALEFPFTF"
     J_segment       265..302
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           73 a           74 c           86 g           72 t
ORIGIN      
        1 acatggggga gagccggcct ccatctcctg caggtctagt cagagcctct tggatagtga
       61 ggatggaaac acctatttgg aatggtacct gcagaagcca ggccagtctc cacagctctt
      121 gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      181 agacactgat ttcacactga taatcagcag agtggaggct gaggatgttg gggtttatta
      241 ctgcatgcaa gctctagagt ttccattcac cttcggcccc gggaccaaac tggatatcaa
      301 acgag
//
LOCUS       KCVT01002154             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14315:12079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002154
VERSION     KCVT01002154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14315:12079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79679.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttaac atggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002155             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17735:22007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002155
VERSION     KCVT01002155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17735:22007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79680.1"
                     /translation="CQQYDSDTHTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           90 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccacttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgaca cgcacacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002156             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:28408:11999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002156
VERSION     KCVT01002156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:28408:11999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79681.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          122 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cacccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggcgtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002157             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16194:9350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002157
VERSION     KCVT01002157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16194:9350"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79682.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          125 c          112 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccaac aaaaacctgg gcaggctccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagactt cactctcacc atcaccagcc tggagcctga agatgttgca gtctattttt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002158             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12791:8390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002158
VERSION     KCVT01002158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12791:8390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79683.1"
                     /translation="CQKYSSPPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           97 a          126 c          108 g           93 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatttt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagtttagc ctggtaccag cacaaagttg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcaccctcac catcagcagc ctggagcctg aagattttgt agtgtactac
      361 tgtcagaaat atagtagtcc cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01002159             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15057:4656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002159
VERSION     KCVT01002159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15057:4656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79684.1"
                     /translation="CQQSYRYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atgtatcttg catccacttt gcagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagatgctgc aacttattac
      361 tgtcagcaga gttatcgtta tccgctcact ttcggtggag ggacccaggt ggaaatcaat
      421 cgag
//
LOCUS       KCVT01002160             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:11348:8919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002160
VERSION     KCVT01002160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11348:8919"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79685.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          115 c          110 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca acagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caatttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002161             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20267:17243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002161
VERSION     KCVT01002161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20267:17243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79686.1"
                     /translation="CLQYNSSPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacata gcatggacat gagggtccct gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcgagtcaga
      181 ctattagcag ctggttagac tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctttaaggc atccagtttg caaagtgggg tcccctcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtctacagta caatagtagc ccactcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002162             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7069:9729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002162
VERSION     KCVT01002162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7069:9729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79687.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          115 c          107 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagcagttct ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002163             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17368:12107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002163
VERSION     KCVT01002163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17368:12107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79688.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          117 c          118 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctttcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagagt cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002164             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23879:18389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002164
VERSION     KCVT01002164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23879:18389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79689.1"
                     /translation="CQQVYSSPFTF"
     J_segment       388..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          115 c          110 g          104 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg tccctgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgatatcc agatgaccca
      121 gtctccatct gccttgtctg catctgtggg agacagagtc accatctctt gccgggcaag
      181 tcagaacatt tatagttatt tagcgtggta tcaacagaaa ccagggaaag cccctaagct
      241 cctgatctat gctgtatcca gattgcaaag tggggttccc tctcggttca gcggcagtgg
      301 aactgggaca gatttcactc tcagcatcag cagcctacag cctgaagatt ctgccggtta
      361 ttactgtcaa caggtttata gtagtccatt cactttcggc cccgggacca aactggctat
      421 caaacgag
//
LOCUS       KCVT01002165             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8860:19207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002165
VERSION     KCVT01002165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8860:19207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79690.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacatc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002166             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9538:13875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002166
VERSION     KCVT01002166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9538:13875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79691.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctacacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002167             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15725:16519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002167
VERSION     KCVT01002167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15725:16519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..322
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79692.1"
                     /translation="CMQALEFPLTF"
     J_segment       323..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           81 a           90 c          107 g           84 t
ORIGIN      
        1 acatggggga tccagcgggg acattgtgat gacccagact ccactctccc tgtccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atggtgagga
      121 tggaaacacc tacttggaat ggtatttcca gaagccaggc cagtctccac agctcttgat
      181 ttatgaggtt tccaagcggg cctctggagt cgcagacagg ttcagtggca gtgggtcagg
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttatcactg
      301 catgcaagct ctagagtttc ctctcacttt cggcggaggg accaaggtgg agatcaaacg
      361 ag
//
LOCUS       KCVT01002168             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:24489:12206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002168
VERSION     KCVT01002168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24489:12206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79693.1"
                     /translation="CQQYHSTPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          108 a          112 c          120 g          102 t
ORIGIN      
        1 acatgggggg agctacaaca ggcaggcagg ggcagcaaga tggtgtcaca gacccaagtc
       61 ttcatttccc tgttgctctg gatctctggt gcctgtgggg acattgtgat gacccagtct
      121 ccagactccc tggctgtgtc tctgggagag agggtcacca tcaactgcaa gtccagccag
      181 agtcttttat acaggtccaa caataagaac tacgtagcct ggtatcagca gaaagtagga
      241 caggctccta agttgctcat ttattgggca tcctcccggc aatccggggt ccctaaccga
      301 ttcagtggcg gtggatctgg gtcagatttc actctcacca tcaatggcct tcagactgaa
      361 gatgtggcag tatattactg tcagcagtat catagcactc cctggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002169             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9405:11210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002169
VERSION     KCVT01002169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9405:11210"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79694.1"
                     /translation="CQQHNTYPYTF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           99 a          112 c          102 g           91 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattagta atgatttagc
      181 ctggtatcag cagaaaccag ggaaagcccc gaagcccctg atcttttacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagc ataatactta
      361 cccgtacact tttggccagg ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002170             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16549:7151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002170
VERSION     KCVT01002170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16549:7151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..394
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79695.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagacttccc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002171             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6509:9705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002171
VERSION     KCVT01002171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6509:9705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79696.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 tacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002172             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10846:9704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002172
VERSION     KCVT01002172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10846:9704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79697.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          112 a          117 c          103 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcacgatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gttctgggac
      301 agatttcact ctcaccatca acaacctgca gcctgaagat atcgcaacat attactgtca
      361 acaacatgat gattcccctc ggaccttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002173             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12781:21567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002173
VERSION     KCVT01002173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12781:21567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79698.1"
                     /translation="CQQHNGYLPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          117 c          107 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac aggaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatat cttccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002174             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12383:9058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002174
VERSION     KCVT01002174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12383:9058"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..370
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79699.1"
                     /translation="CQQGYYTPFTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT           97 a          121 c          111 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgcccgatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atctcttgcc gagccagtca
      181 gggtattagc agctggttag cctggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctataag gcgtccagtt tggcaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacggat tacactctca ccatcagcag cctgcagcct gaagattttg ctacttatta
      361 ttgtcaacag ggttactata ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 tcgag
//
LOCUS       KCVT01002175             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11543:7708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002175
VERSION     KCVT01002175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11543:7708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79700.1"
                     /translation="CQQHDDSPRTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          110 a          117 c          108 g           86 t
ORIGIN      
        1 acatgggggc agtctcagac aggacacagc atggacacga gggtccccgc tcagctcctg
       61 gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcagagc cagtcaggat
      181 attaacacct ggttggcctg gtatcaacag aagccaggga aagcccctaa ggtcctgatc
      241 tataggacat ccaatttgga aacaggggtc ccatcaaggt tcagtggaag tggatctggg
      301 acagatttca ctctcaccat caacagcctg cagcctgaag atatcgcaac atattactgt
      361 caacagcatg atgattcccc tcggacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01002176             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9332:16778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002176
VERSION     KCVT01002176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9332:16778"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79701.1"
                     /translation="CQQHNTYPLTF"
     J_segment       386..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          118 c          102 g           94 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcagga
      181 cattagtaat gatttagcct ggtatcagca gaaaccaggg aaagccccga agcccctgat
      241 gtattacgca tccaatttgg aaaatggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa gttattactg
      361 tcaacagcat aatacttacc cattgacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01002177             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12403:11233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002177
VERSION     KCVT01002177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12403:11233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79702.1"
                     /translation="CQQYNNDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          111 c          111 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tagaagttat ttagcgtggt atcagatgag accagggaaa gccccgaggg ccttaatcta
      241 ttacgcgacc attttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatcg gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acagtataac aatgacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002178             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15245:20384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002178
VERSION     KCVT01002178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15245:20384"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79703.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          116 c          111 g           89 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc atcatcactt gcagagccag
      181 tcacgatatt aacaactggt tggcctggta tcaacagaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccattag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01002179             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15553:19434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002179
VERSION     KCVT01002179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15553:19434"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79704.1"
                     /translation="CQRYSYSTWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g           92 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gtttggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcttccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagag gtatagttac tccacgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002180             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25278:10203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002180
VERSION     KCVT01002180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25278:10203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79705.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          118 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctgttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagaatgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa ttcaaacgag
//
LOCUS       KCVT01002181             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10191:17893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002181
VERSION     KCVT01002181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10191:17893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79706.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          117 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tacatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002182             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19537:11821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002182
VERSION     KCVT01002182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19537:11821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79707.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat gggaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac agtgatttta cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002183             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13032:21862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002183
VERSION     KCVT01002183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13032:21862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79708.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagg ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002184             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:9708:18314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002184
VERSION     KCVT01002184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9708:18314"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79709.1"
                     /translation="CQQHDNSPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          119 c          111 g           89 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctc tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcaggg
      181 tgttagcgac tggttggcct ggtatcaaca gagaccaggg aaagccccta aactcctgat
      241 ctatagggcg tccaatttgg atacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcta catattactg
      361 tcaacagcat gataattccc ctccgacgtt cggccaaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002185             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9265:10390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002185
VERSION     KCVT01002185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9265:10390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79710.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatgt cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002186             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14047:10517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002186
VERSION     KCVT01002186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14047:10517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79711.1"
                     /translation="CLQGYSPPHTF"
     J_segment       390..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          118 c          109 g           96 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtcggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gagaagctcc taagcgcctg
      241 atctatgctg catccactct gcaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcat catcagcagc ctgcagcctg aggattttgc agcttattac
      361 tgtctacagg gttatagtcc ccctcacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002187             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6062:19720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002187
VERSION     KCVT01002187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6062:19720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    54..375
                     /note="immunoglobulin light chain variable region"
     V_region        54..375
     V_segment       54..328
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79712.1"
                     /translation="CQQHNNYSPTF"
     J_segment       341..375
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>378
                     /gene="IGKC"
BASE COUNT          100 a          104 c           92 g           82 t
ORIGIN      
        1 acatgggggg agtcagaacc actcagctca gctggctccc aggtgccaga tgtgacatcc
       61 agatgaccca gtctccaccc tccctgtctg catctgtagg agacacagtc accatcactt
      121 gtcgggcaag tcagggcatt agcaatgatt tagcctggta tcagctgaaa ccagggaaag
      181 ccccgaagcc cctgatctat tacgcatcca atttggaaag tggggtccca tcaaggttca
      241 gcggcagtgg atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt
      301 ttgcaactta ttactgtcaa caacataata attactctcc cactttcggc ggagggacca
      361 aggtggagat caaacgag
//
LOCUS       KCVT01002188             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19336:20373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002188
VERSION     KCVT01002188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19336:20373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79713.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          122 c          121 g          103 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgaga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttgcac tggtacctgc agaagccagg
      241 ccagtctcca cagctcttaa tttacgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002189             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19749:6703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002189
VERSION     KCVT01002189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19749:6703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79714.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          116 c           99 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc agactggaga tcaaacgag
//
LOCUS       KCVT01002190             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11974:14949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002190
VERSION     KCVT01002190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11974:14949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..409
                     /note="immunoglobulin light chain variable region"
     V_region        95..409
     V_segment       95..372
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79715.1"
                     /translation="CQQDYNYSF"
     J_segment       377..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           99 a          106 c          114 g           93 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacatgagg gtccccgtgc agctcctggg
       61 gctcctgttg ctctggctcc aaggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagaat cacagtcact tgccgggcga gtcaaggcat
      181 taagaaggag ttaggtggta tcagtagaaa ccagggaaag tcccaacact cctggtctct
      241 gctgcctcca ctttgcagac gggggtctca tctcggttca gtggctgtgg atctgggaca
      301 gatttcactc acaccgtcag cagcctgcag cctgaagatg ttgcaactaa ttactgtcaa
      361 caggattata attactcttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002191             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14502:17581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002191
VERSION     KCVT01002191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14502:17581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..402
                     /note="immunoglobulin light chain variable region"
     V_region        111..402
     V_segment       111..364
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <342..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79716.1"
                     /translation="CIQALEFPWTF"
     J_segment       365..402
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>405
                     /gene="IGKC"
BASE COUNT           93 a          100 c          113 g           99 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccatctcctg caggtctagt cagagcctct tggatagtga ggatggaaac acctatttgg
      181 attggtacct gcagaagcca ggccagtctc cacaactctt gatttatgag gtttccaatc
      241 gggcctctgg agtcccagac aggttcagtg gcagtgggtc tgacactgat ttcacactga
      301 aaatcagcag agtggaggct gaggatgttg gggtttatta ctgcattcaa gctctagagt
      361 ttccgtggac gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002192             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14231:4270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002192
VERSION     KCVT01002192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14231:4270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79717.1"
                     /translation="CMQPLEFPWTF"
     J_segment       322..359
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           84 a           89 c          106 g           83 t
ORIGIN      
        1 acatggggga tccagtgggg acattgtgat gacccagact ccactgtccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgtgg gtctagtcag agcctcttgg atagtgagga
      121 tggaaacacc tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat
      181 ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaacct ctagagtttc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      361 ag
//
LOCUS       KCVT01002193             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17747:11910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002193
VERSION     KCVT01002193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17747:11910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79718.1"
                     /translation="CLHYNSAPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          114 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtcagg
      181 acatcagcaa ttatttaaat tggtttcagc agaaaccagg aaaagctcct aagcgcctga
      241 tctatgatgc atccagtttg caaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagtatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacatta taacagtgcc cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002194             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22001:11851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002194
VERSION     KCVT01002194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22001:11851"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79719.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          109 c          110 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctctggggga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agatatttaa attggtatca gcagaaacct gggaaagccc ctaagttcct
      241 gatctattat gtaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ttgtcaacag tataatagtt taccgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002195             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15544:6120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002195
VERSION     KCVT01002195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15544:6120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79720.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           92 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagattt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002196             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:28491:10504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002196
VERSION     KCVT01002196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28491:10504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79721.1"
                     /translation="CQQYADSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          116 c          109 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt taccatcact tgcagagcca gtcaggatat
      181 tagcaactgg ttggcctggt atcaacagag accagggaaa gcccctaagg tcctgatcta
      241 taggacatcc aatttggaag caggggtccc atcaaggttc agtggaaccg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagtatgct gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002197             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16915:3491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002197
VERSION     KCVT01002197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16915:3491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79722.1"
                     /translation="CMQGTQLLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g           95 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca accggcctcc acctcctgca ggtctagtca aagccttcta
      181 cacactgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg agactgagga tgttggagtt
      361 tattactgca tgcaaggtac acagcttctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01002198             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14168:5023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002198
VERSION     KCVT01002198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14168:5023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..336
                     /note="immunoglobulin light chain variable region"
     V_region        15..336
     V_segment       15..299
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <276..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79723.1"
                     /translation="CQQGDSYPRTF"
     J_segment       301..336
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>339
                     /gene="IGKC"
BASE COUNT           92 a           83 c           86 g           78 t
ORIGIN      
        1 acatgggcag atgtgacatt cagatgtccc agtctccttc ctccctgtct gcatctgtgg
       61 gagacagagt caccatcact tgccgggcaa gtcaggacat tagagattat ttaaattggt
      121 atcagcagca accggggaaa gcccctaaac tcctgatgta ttatgcaaac agtctggcaa
      181 gtggagtccc atcaaggttc agcggcagtg gatctgggac agaattcagt ctcaccatca
      241 gcagcctgca gcctgaagat tttgcaactt attactgtca acagggtgac agttatcctc
      301 ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002199             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:5000:17122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002199
VERSION     KCVT01002199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:5000:17122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79724.1"
                     /translation="CQQYNSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          111 c          111 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgtatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatat
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002200             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24367:11303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002200
VERSION     KCVT01002200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24367:11303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79725.1"
                     /translation="CQQYHSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatcg gcaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattagcag ttatttagcg tggtatcggc agaagccagg gaaagccccg gagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tacagcctga agattttgca acttattact
      361 gtcaacagta tcacagtgac tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002201             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17479:3534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002201
VERSION     KCVT01002201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17479:3534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79726.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca tactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002202             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17243:9458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002202
VERSION     KCVT01002202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17243:9458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79727.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          113 c          111 g           94 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcaac tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002203             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:24535:8370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002203
VERSION     KCVT01002203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24535:8370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79728.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          123 c          113 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag caaaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca gattcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002204             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15665:2980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002204
VERSION     KCVT01002204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15665:2980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79729.1"
                     /translation="CQQYNSEPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          112 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg tgtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg agccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002205             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8052:11589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002205
VERSION     KCVT01002205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8052:11589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79730.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccttgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002206             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11439:20307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002206
VERSION     KCVT01002206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11439:20307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79731.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           96 a          125 c          113 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggtt cccaaactcc
      241 ttgtccatag tgcattcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002207             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:25895:12393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002207
VERSION     KCVT01002207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25895:12393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..341
                     /note="immunoglobulin light chain variable region"
     V_region        23..341
     V_segment       23..306
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79732.1"
                     /translation="CQQHNSYPLTF"
     J_segment       308..341
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>347
                     /gene="IGKC"
BASE COUNT           90 a           97 c           83 g           77 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
       61 atctgtagga gacacagtca ccatcacttg tcgggcaagt cagggcatta ccaatgattt
      121 agcctggtat cagcagaaac cagggaaagc cccgaagccc ctgatctatt acgcatccaa
      181 tttggaaact ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agcataatag
      301 ttacccactc actttcggcg gagggaccaa ggtggagatc agacgag
//
LOCUS       KCVT01002208             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21937:8150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002208
VERSION     KCVT01002208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21937:8150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79733.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002209             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4999:18171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002209
VERSION     KCVT01002209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4999:18171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..367
                     /note="immunoglobulin light chain variable region"
     V_region        28..367
     V_segment       28..330
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <307..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79734.1"
                     /translation="CMQGLEFPRTF"
     J_segment       332..367
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           84 a           96 c          105 g           85 t
ORIGIN      
        1 acatgggggc tccctggatc cagtggtgac attgtgatga cccagactcc actctccctg
       61 cccgtcaccc ttggagagcc ggcctccatc tcctgcagat ctagtcagag tctcttggat
      121 agtgcggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca gtctccacag
      181 ctcttgattt atgaggtctc cgaccgggcc tctggagtcc cagacaggtt cagtggcagt
      241 ggctcagaca ctgatttcac actaaagatc agcagagtgg aggctgagga tgttggggtt
      301 tattactgca tgcaaggtct agagtttcct cggacgttcg gccaagggac caaggtggaa
      361 atcaaacgag
//
LOCUS       KCVT01002210             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16214:12712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002210
VERSION     KCVT01002210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16214:12712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79735.1"
                     /translation="CMQALEFPYSF"
     J_segment       403..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctattgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcatg gatagtgggg atgtaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca catctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acacggattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtacagtt ttggccaggg
      421 gaccagagtg gagatcaaac gag
//
LOCUS       KCVT01002211             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11316:4667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002211
VERSION     KCVT01002211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11316:4667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79736.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgttacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002212             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7067:9187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002212
VERSION     KCVT01002212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7067:9187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79737.1"
                     /translation="CQQYDTDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          118 c          112 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacactgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002213             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17319:10381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002213
VERSION     KCVT01002213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17319:10381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    17..338
                     /note="immunoglobulin light chain variable region"
     V_region        17..338
     V_segment       17..286
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <278..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79738.1"
                     /translation="CLQGYIIPYNF"
     J_segment       301..338
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>341
                     /gene="IGKC"
BASE COUNT           88 a           82 c           87 g           84 t
ORIGIN      
        1 acatggggcc agatgtgaca tccagatgac ccagtctcca tcttccctgt ctgcatcggt
       61 aggagacaga gtcaccatca cttgccgggc aagtcaggac attagcgatt ttttaagttg
      121 gtatcagcag aaaccaggaa aacctcctaa gcgcctgatt tatgctgcat ccagtttgga
      181 aagtggggtc ccgtcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat
      241 cagcagcctg cagcctgaag attttgcggc ttattattgt ctacagggtt atattatccc
      301 gtacaatttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002214             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7059:14910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002214
VERSION     KCVT01002214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7059:14910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79739.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          120 c          107 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca acataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002215             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:24704:9539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002215
VERSION     KCVT01002215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24704:9539"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79740.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcaccagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01002216             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22982:14202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002216
VERSION     KCVT01002216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22982:14202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79741.1"
                     /translation="CQQYNSDPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          117 c          105 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaagcc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      421 aacgag
//
LOCUS       KCVT01002217             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23825:14504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002217
VERSION     KCVT01002217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23825:14504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79742.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           99 a          116 c          118 g           99 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga caacctccta
      241 aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac gatggtgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 agatcaaacg ag
//
LOCUS       KCVT01002218             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:28536:13559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002218
VERSION     KCVT01002218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:28536:13559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79743.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          110 g           94 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggcag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc atcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002219             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25881:13529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002219
VERSION     KCVT01002219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25881:13529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79744.1"
                     /translation="CQHSYGTLTWAF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          117 c          114 g           94 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtagggga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaag aactatttac attggtatca gcagaaacca gggaaagccc ctaggctcct
      241 gatctatgct gcatccactt tgcaaagtgg ggtcccatca aggttcaccg gcagtggatc
      301 tggggcagat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agttatggta ccctcacgtg ggcgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01002220             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:24147:17271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002220
VERSION     KCVT01002220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24147:17271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..313
                     /note="immunoglobulin light chain variable region"
     V_region        29..313
     V_segment       29..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79745.1"
                     /translation="CMQPLEFPWTF"
     J_segment       276..313
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           78 a           74 c           90 g           74 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc tccatctcct gcaggtctag tcagagcctc
       61 ttggatagtg aggatggaaa cacttatttg gaatggtacc tgcagaagcc aggccagtct
      121 ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt
      181 ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt
      241 ggggtttatt actgcatgca acctctagag tttccgtgga cgttcggcca agggaccaag
      301 gtggaaatca aacgag
//
LOCUS       KCVT01002221             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:5911:4838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002221
VERSION     KCVT01002221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5911:4838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79746.1"
                     /translation="CQQYNSLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaagg tactcatcta
      241 ttatgtaaac cgtctggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01002222             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11249:12380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002222
VERSION     KCVT01002222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11249:12380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79747.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tacatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01002223             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19770:13308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002223
VERSION     KCVT01002223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19770:13308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79748.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          125 c          118 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgctgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002224             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8179:7154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002224
VERSION     KCVT01002224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8179:7154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79749.1"
                     /translation="CQQYNNLPLTF"
     J_segment       382..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT          106 a          111 c          105 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcgtctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcaattat ttaaattggt atcaacagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attcctgtca
      361 acagtataat aatttaccgt tgacgttcgg ccaagggacc atggtggatt tcaaacgag
//
LOCUS       KCVT01002225             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15306:11890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002225
VERSION     KCVT01002225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15306:11890"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79750.1"
                     /translation="CLQYKNYPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          115 c           98 g          101 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gttattatca attatttaaa ttggtttcag cagaaaccag ggaaagcccc taagctcctg
      241 atatatgctg catccagatt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaaacta cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01002226             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10483:16790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002226
VERSION     KCVT01002226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10483:16790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79751.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          114 c          113 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tagcagttat ttagcgtggt atcggcagaa gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atttctgtca
      361 acagtatgac agtgactcgc tcactttcgg tggagggacc agggtggaga tcaaacgag
//
LOCUS       KCVT01002227             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4276:14427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002227
VERSION     KCVT01002227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4276:14427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79752.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002228             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7431:12676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002228
VERSION     KCVT01002228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7431:12676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79753.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           86 t
ORIGIN      
        1 acatgggggt ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002229             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14926:8066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002229
VERSION     KCVT01002229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14926:8066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79754.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          118 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tggagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002230             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18085:7940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002230
VERSION     KCVT01002230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18085:7940"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79755.1"
                     /translation="CQQHNNYSPTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          108 a          120 c          108 g           92 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccaccc tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag
      181 tcagggcatt agcaatgatt tagcctggta tcagctgaaa ccagggaaag ccccgaagcc
      241 cctgatctat tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa caacataata attactctcc cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002231             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14236:15777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002231
VERSION     KCVT01002231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14236:15777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79756.1"
                     /translation="CMQALEFPWTF"
     J_segment       312..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           84 a           86 c          101 g           81 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccagtctccc tgcccgtcac ccttagagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctaca gaggccaggc cagtctccac agctcttaat ttatgaggtt
      181 tcctaccggg cctctggagt cccagacagg ttcagtggga gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagtttc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002232             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12805:9460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002232
VERSION     KCVT01002232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12805:9460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..346
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79757.1"
                     /translation="CMQPLEFPWTF"
     J_segment       347..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           97 c          113 g           90 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact gtccctgccc gtcacccttg gagagccggc ctccatctcc tgtgggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc
      181 caggccagtc tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aacctctaga gtttccgtgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01002233             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:22420:8622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002233
VERSION     KCVT01002233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22420:8622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79758.1"
                     /translation="CLQGYITPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          112 c          110 g          100 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg gcttattatt
      361 gtctacaggg ttatattacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002234             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25119:11826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002234
VERSION     KCVT01002234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25119:11826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79759.1"
                     /translation="CQQHNTYPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          107 a          117 c          105 g           92 t
ORIGIN      
        1 acatgggggg agaaccactc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaca gtcaccatca cttgtcgggc aagtcaggac
      181 attagtaatg atttagcctg gtatcagcag aaaccaggga aagccccaaa gcccctgatc
      241 ttttacgcat ccaatttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagcata atacttaccc gtacactttt ggccagggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01002235             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20011:5829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002235
VERSION     KCVT01002235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20011:5829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79760.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccatcgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002236             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12639:17910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002236
VERSION     KCVT01002236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12639:17910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79761.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002237             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16971:6592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002237
VERSION     KCVT01002237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16971:6592"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79762.1"
                     /translation="CQQDYSYPWTF"
     J_segment       384..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          116 c          114 g           93 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacat gagggtcccc gtgcagctcc
       61 tggggctcct gttgctctgg ctccaaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccgt cacttgccgg gcgagtcaag
      181 gcattaacaa ggagttaatc tggtatcagc agaaaccagg gaaagcccct acactcctga
      241 tctatgctgc ctccaccttg cagacggggg tctcatctcg gttcagtggc agtggagttg
      301 ggacagactt cactctcacc atcagcagcc tgcagcctga agatgttgct acttatttct
      361 gtcaacagga ttatagttac ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002238             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14414:22851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002238
VERSION     KCVT01002238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14414:22851"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79763.1"
                     /translation="CQHSHGSPITF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          114 c          109 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgtttac aactatttac attggtatca gcagaaacca gggaaagtcc ctaaggtcct
      241 gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggactgat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002239             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18446:4240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002239
VERSION     KCVT01002239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18446:4240"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79764.1"
                     /translation="CLQQCNNPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          116 c          106 g           93 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctacat ctgcaggaga cagaatcacc atcgcttgca gggcaagtca
      181 gggcattaac acttatttaa attggtgtca acagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccagcagcag cctgcagcct gaagattttg caactcatta
      361 ctgtctacag caatgtaata acccgctcac tttcgctgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002240             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14888:15839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002240
VERSION     KCVT01002240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14888:15839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79765.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          105 a          125 c          120 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcaaaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01002241             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22239:5633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002241
VERSION     KCVT01002241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22239:5633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79766.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          113 c          113 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 cgtcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcgttagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002242             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:8336:11295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002242
VERSION     KCVT01002242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8336:11295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79767.1"
                     /translation="CQQHDNSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           89 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctctct gtatctgtag gagacagagt caccatcact tgcagagcca gtcagggtgt
      181 tagcgactgg ttggcctggt atcaacagag accagggaaa gcccctaaac tcctgatcta
      241 tagggcgtcc aatttggata caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgctacat attactgtca
      361 acagcatgat aattcccctc cgacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002243             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:23840:16811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002243
VERSION     KCVT01002243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23840:16811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79768.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccagg ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002244             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20231:14614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002244
VERSION     KCVT01002244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20231:14614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79769.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgt ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002245             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18916:3252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002245
VERSION     KCVT01002245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18916:3252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79770.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01002246             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12672:13226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002246
VERSION     KCVT01002246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12672:13226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79771.1"
                     /translation="CIQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          125 c          114 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggaatg gttcctccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atacaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01002247             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18758:9732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002247
VERSION     KCVT01002247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18758:9732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79772.1"
                     /translation="CQQYNTLPLTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          108 a          110 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggcg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctcttatac aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatacttta ccgttgacgt tcggccaagg gaccaaggtg gaaatcaaag
      421 gag
//
LOCUS       KCVT01002248             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19112:16468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002248
VERSION     KCVT01002248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19112:16468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..378
                     /note="immunoglobulin light chain variable region"
     V_region        118..378
     V_segment       118..338
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79773.1"
                     /translation="CQRYSYSTWTF"
     J_segment       341..378
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>381
                     /gene="IGKC"
BASE COUNT           90 a          103 c          106 g           82 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 cctgcagggc cagtcagagt gttggcagca gcttggtttg gtaccagcag aaacctgggc
      181 aggcccccag gctcctcatc tatggtgcat ccagcagggc cactggcatc ccagacaggt
      241 tcagtggcag tgggtctggg acagagttca ctctcaccat cagcagcctg gagcctgaag
      301 attttgcagt atattactgt cagaggtata gttactccac gtggacgttc ggccaaggga
      361 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002249             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:23437:18000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002249
VERSION     KCVT01002249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23437:18000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79774.1"
                     /translation="CQQYNSEPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat ttactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga gccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002250             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18923:20064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002250
VERSION     KCVT01002250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18923:20064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79775.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002251             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:4571:14326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002251
VERSION     KCVT01002251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4571:14326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    68..389
                     /note="immunoglobulin light chain variable region"
     V_region        68..389
     V_segment       68..352
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79776.1"
                     /translation="CQQNSNWPLTF"
     J_segment       353..389
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>392
                     /gene="IGKC"
BASE COUNT           89 a          117 c          104 g           82 t
ORIGIN      
        1 acatgggatg gaagccccag cacagcttct cttcctcctg ctgctctggc tcccagatac
       61 caccggagaa atagtgctga cgcagtctcc agccaccctg tctttgtctc caggagaaag
      121 agccaccctc tcctgcaggg ccagtcagag tgtcagcagc agcttagcct ggtaccagca
      181 gatacctggg caggctccca gactcctcat ctatggtgca tccaacaggg ccactggcat
      241 cccaggcagg ttcagtggca gtgggtctgg gacagagttc actctcacca tcagcagcct
      301 ggagcctgaa gatgttgcac tttattattg tcagcagaac agtaactggc ctctcacttt
      361 cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002252             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16214:9840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002252
VERSION     KCVT01002252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16214:9840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..362
                     /note="immunoglobulin light chain variable region"
     V_region        85..362
     V_segment       85..320
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <302..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79777.1"
                     /translation="CQQYDSDSLTF"
     J_segment       325..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           91 a           97 c           98 g           79 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggaga cagagtcacc atcacttgtc gggcgactca
      121 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      181 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      241 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      301 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01002253             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17221:10500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002253
VERSION     KCVT01002253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17221:10500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79778.1"
                     /translation="CQHSHGSPITF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          106 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 ttacaactat ttacattggt atcagcagaa accagggaaa gcccctaagg tcctgatcta
      241 tgctgcatcc actttgcaaa gtggagtccc atcaaggttc agcggcagtg gatctgggac
      301 tgatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagtcat ggatccccta tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002254             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16821:23899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002254
VERSION     KCVT01002254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16821:23899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79779.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaagctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002255             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14568:17851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002255
VERSION     KCVT01002255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14568:17851"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79780.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          117 g          111 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggatatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgtgg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002256             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23719:8401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002256
VERSION     KCVT01002256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23719:8401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79781.1"
                     /translation="CLQGYITPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          112 c          111 g          100 t
ORIGIN      
        1 acatggggag agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacttccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tgcaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ttgtctacag ggttatatta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002257             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23508:13821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002257
VERSION     KCVT01002257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23508:13821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79782.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcaac agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002258             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6237:3704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002258
VERSION     KCVT01002258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6237:3704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79783.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtcgg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002259             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24288:19985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002259
VERSION     KCVT01002259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24288:19985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79784.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccaaccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002260             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:25323:5867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002260
VERSION     KCVT01002260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25323:5867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79785.1"
                     /translation="CMQSLEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002261             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:23774:10961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002261
VERSION     KCVT01002261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:23774:10961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79786.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          115 c          107 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcaggatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc attttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgaa
//
LOCUS       KCVT01002262             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24666:22564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002262
VERSION     KCVT01002262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24666:22564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79787.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccggacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002263             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13792:8804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002263
VERSION     KCVT01002263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13792:8804"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79788.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          118 c          107 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatttcgca acatatttct
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002264             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6598:17532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002264
VERSION     KCVT01002264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6598:17532"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79789.1"
                     /translation="CQQGYGFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          102 g          102 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cgcgatcact tgcctggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tatggcatcc aatttacatg gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca acagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat ggttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01002265             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17647:5837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002265
VERSION     KCVT01002265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17647:5837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79790.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg aaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002266             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21839:7887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002266
VERSION     KCVT01002266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21839:7887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79791.1"
                     /translation="CQQYNSDLFTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          111 c          107 g           95 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catttgtagg agacagagtc accatcactt gtcggacgag tcagggcatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 tacgcgtcca ttttggaaag tggggtccca tcaaggttca gcggcagtgg atatgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataaca gtgacctgtt cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002267             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10375:13199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002267
VERSION     KCVT01002267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10375:13199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79792.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01002268             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12126:21861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002268
VERSION     KCVT01002268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12126:21861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79793.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          127 c          122 g           87 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag
      121 tgctgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg
      241 ctcccagact cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca
      301 gtggcagtgg gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg
      361 ttgcacttta ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01002269             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17328:2613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002269
VERSION     KCVT01002269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17328:2613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..406
                     /note="immunoglobulin light chain variable region"
     V_region        85..406
     V_segment       85..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79794.1"
                     /translation="CQQYDSDPFTF"
     J_segment       371..406
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>409
                     /gene="IGKC"
BASE COUNT           99 a          112 c          108 g           90 t
ORIGIN      
        1 acatggggag gacacagcat ggacatgagg gtccccgctc agctcctagg actcctgctg
       61 ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc ctccctgtct
      121 gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat tcgcagttat
      181 ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta ttacgcgtcc
      241 gctttggaaa gtggggtccc atcaagggtc agcggcagtg gatctgggac agagttcact
      301 ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca acaatatgac
      361 agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01002270             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14008:10090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002270
VERSION     KCVT01002270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14008:10090"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79795.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          117 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct acttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac gctgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggcat ttattactgc atgcaaggtc tggagtttcc aatcactttc ggccccggga
      421 ccaaactgga gatcaaacga g
//
LOCUS       KCVT01002271             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6411:15229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002271
VERSION     KCVT01002271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6411:15229"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..279
                     /note="immunoglobulin light chain variable region"
     V_region        9..279
     V_segment       9..227
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <219..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79796.1"
                     /translation="CLQGDTAPFTF"
     J_segment       244..279
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>282
                     /gene="IGKC"
BASE COUNT           74 a           67 c           76 g           65 t
ORIGIN      
        1 acatggggag agtcaccatc acttgccggg caagtcaggg cattaacgat tatttaagtt
       61 ggtatcagca gaaaccagga aaacctccta agcgcctgat ttatgctgca tccagtttgg
      121 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca
      181 tcagcagcct gcagcctgaa gattttgcag cttattactg tctacagggt gatactgccc
      241 cgttcacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002272             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:27393:14235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002272
VERSION     KCVT01002272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:27393:14235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79797.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          124 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cggtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002273             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11192:7731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002273
VERSION     KCVT01002273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11192:7731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79798.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggggatcaa
      421 acgag
//
LOCUS       KCVT01002274             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:9267:5057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002274
VERSION     KCVT01002274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9267:5057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79799.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           91 a          117 c          125 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agcggggaca ttgtgatgac ccagactcca
      121 ctctccctgt ccgtcaccct tggagagtcg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggatg gtgaggatgg aaacacctac ttggaatggt atttgcagaa gccaggccag
      241 tctccgcagc tcttgattta tgaggtttcc aagcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaattca gcagagtgga ggctgaggat
      361 gttggggttt atcactgcat gcaagctcta gagtttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01002275             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15094:13717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002275
VERSION     KCVT01002275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15094:13717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79800.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccagttt ggaaagtggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01002276             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18506:19756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002276
VERSION     KCVT01002276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18506:19756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79801.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          116 c           98 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctcca gcctgaagat tttgcaactt attactgtct
      361 acagtataag agtttcccgt atacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01002277             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20570:11438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002277
VERSION     KCVT01002277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20570:11438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79802.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac cttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002278             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19751:9964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002278
VERSION     KCVT01002278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19751:9964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79803.1"
                     /translation="CMQGLEYPYSF"
     J_segment       404..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaagctc cctgctcagc
       61 tcctggggct gctaatgctc tggctccctg gatccagtgg ggatattgtg atgacccaga
      121 ctccactctc cctgccagtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgcg gatggaaaaa cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagcccttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa tatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag gtttagagta tccgtacagt tttggccagg
      421 ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01002279             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22622:15629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002279
VERSION     KCVT01002279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22622:15629"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79804.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          116 c          110 g           88 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg tcggagacag agtctccatc acttgcagag ccagtcagga
      181 tattaacaag tggttggcct ggtatcaaca gaaaccaggg aaagccccta aggtcctgat
      241 ctatagggca tccaatttgc aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattcgc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002280             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12547:12992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002280
VERSION     KCVT01002280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12547:12992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79805.1"
                     /translation="CQQHDNSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          118 c          105 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaatatctgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat aattcccctc ggacgttcgg ccaagggacc aaggtggaag tcaaacgag
//
LOCUS       KCVT01002281             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5652:16680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002281
VERSION     KCVT01002281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5652:16680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..282
                     /note="immunoglobulin light chain variable region"
     V_region        115..282
     V_segment       115..263
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79806.1"
                     /translation="CQKYSSSPFTF"
     J_segment       264..282
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           62 a           78 c           74 g           68 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttatt ttgactcctc
      121 gtctatggtg catccaggag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      181 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      241 tgtcagaagt atagtagttc cccattcact ttcggccccg gg
//
LOCUS       KCVT01002282             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12943:11517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002282
VERSION     KCVT01002282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12943:11517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79807.1"
                     /translation="CLQGYITPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          113 c          112 g           99 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttgcaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 actgtctaca gggttatatt accccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002283             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20338:9026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002283
VERSION     KCVT01002283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20338:9026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..323
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79808.1"
                     /translation="CQQYDSDSLTF"
     J_segment       328..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           89 a           98 c           95 g           86 t
ORIGIN      
        1 acatggggga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      121 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc
      181 cttgatctat tacgcgtccg ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01002284             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21145:12050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002284
VERSION     KCVT01002284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21145:12050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79809.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gatgctgagg
      361 atgttgggct ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga ggtcaaacga g
//
LOCUS       KCVT01002285             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20307:7601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002285
VERSION     KCVT01002285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20307:7601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79810.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           86 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgct gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcaacttagc ctggtaccag cagagacctg ggcagtctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccaggca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga acagtaactg gcctctcact ttcggtggag ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002286             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10588:15376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002286
VERSION     KCVT01002286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10588:15376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79811.1"
                     /translation="CMQALDFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          127 c          113 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 cccccctccc tgcccgtcac ccttggagag gcggcctcca tctcctgtag gtctagtcag
      181 agcctcttcg atactgaaga aggaaacacc tatttggagt ggtacctgca gaggccaggc
      241 cagactccac agctcttgat ttatcaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggac tttattactg catgcaggct ctagactttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01002287             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22930:6640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002287
VERSION     KCVT01002287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22930:6640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79812.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          125 c          119 g           89 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac caacaaaaac ctgggcaggc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01002288             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14263:7655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002288
VERSION     KCVT01002288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14263:7655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..355
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79813.1"
                     /translation="CQQYDSDPRTF"
     J_segment       359..393
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           93 a          110 c          106 g           87 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag
       61 gcgccaaatg tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag
      121 acagagtcac catcacttgt cgggcgagtc agggcattcg cagttattta gcgtggtatc
      181 agcagaaacc agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg
      241 gggtcccatc aaggttcagc ggcagtggat ctgggacaga gttcactctc accatcagca
      301 gcctgcagcc tgaagatttt gcaacttatt actgtcaaca gtatgacagt gacccgcgca
      361 ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01002289             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18175:7464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002289
VERSION     KCVT01002289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18175:7464"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79814.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc cgctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002290             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8871:23748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002290
VERSION     KCVT01002290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8871:23748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79815.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002291             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12278:14658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002291
VERSION     KCVT01002291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12278:14658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79816.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          117 c          108 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattaacac ctggttggcc tggtatcaac agaagccagg gaaagcccct aaggtcctga
      241 tctataggac atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcaacagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002292             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:25025:20846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002292
VERSION     KCVT01002292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25025:20846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79817.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          124 c          111 g           86 t
ORIGIN      
        1 acatggggaa ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcagc agcttagcct ggtaccaaca aaaacctggg caggctccca ggctcctcat
      241 ctatggtgca tccagcaggg ccactggcat cccagacagg ttcagtggca gtgggtctgg
      301 gacagacttc actctcacca tcaccagcct ggagcctgaa gatgttgcag tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002293             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6943:10059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002293
VERSION     KCVT01002293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6943:10059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..350
                     /note="immunoglobulin light chain variable region"
     V_region        11..350
     V_segment       11..313
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <290..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79818.1"
                     /translation="CMQALDFPYSF"
     J_segment       314..350
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>353
                     /gene="IGKC"
BASE COUNT           82 a           89 c           97 g           85 t
ORIGIN      
        1 acatgggggg gacattgtga tgacccagac tccactctcc ctgcccgtca cccttggaga
       61 gccggcctcc atctcctgca ggtctagtca gagcctcttg gatagtgagg atggaaacac
      121 ctatttggaa tggtacctac agaagccagg ccagtctcca cagctcttga tttttgaggt
      181 ttccaaccgg gcctctggag tcccagacag gttcagtggc agtgggtcag acactaattt
      241 cacactgaaa atcagcagtg tggaggctga ggatgttggg gtctattact gcatgcaagc
      301 tctagacttt ccttacagtt ttggccaggg gaccacagtg gagattaaac gag
//
LOCUS       KCVT01002294             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11458:9138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002294
VERSION     KCVT01002294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11458:9138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79819.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..412
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          109 a          118 c          103 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gacaccaaac
      421 gag
//
LOCUS       KCVT01002295             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:26060:12180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002295
VERSION     KCVT01002295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:26060:12180"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    47..365
                     /note="immunoglobulin light chain variable region"
     V_region        47..365
     V_segment       47..330
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79820.1"
                     /translation="CQQNSNWPWTF"
     J_segment       331..365
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>371
                     /gene="IGKC"
BASE COUNT           88 a           99 c          102 g           82 t
ORIGIN      
        1 acatgggggt ctttctgttt tctttcaaat ttcagatacc accggagaaa tagtgatgac
       61 gcagtcccca gccaccctgt ctttgtctcc gggagaaaga gccaccctct cctgcaggac
      121 cagtcagagt gtcagcagca gcttagcctg gtaccagcag aaacctgggc aggctcccag
      181 gctcctcatc tatggtgtat ccagcagggc cactggcatc ccagacaggt tcagtggcag
      241 tgggtctggg acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcagt
      301 ttattattgt cagcagaata gtaactggcc gtggacgttc ggccaaggga ccaaggtgga
      361 aatcagacga g
//
LOCUS       KCVT01002296             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:8020:13101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002296
VERSION     KCVT01002296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8020:13101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79821.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattttgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcggagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggagggt
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002297             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11745:16410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002297
VERSION     KCVT01002297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11745:16410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79822.1"
                     /translation="CQQGYTTPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          114 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattagc agctggttag cctggtatca gcagaaacca gggaaagccc ctaaagtcct
      241 gatctataag gcgtccagtt tggcaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacggat tacactctca ccatcaacag cctgcagcct gaagatttta caacttatta
      361 ttgtcaacag ggttacacta cccctctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002298             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8423:10998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002298
VERSION     KCVT01002298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8423:10998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79823.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          103 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctc atctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002299             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7713:7542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002299
VERSION     KCVT01002299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7713:7542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79824.1"
                     /translation="CQQYDIDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacattga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002300             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24574:21582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002300
VERSION     KCVT01002300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24574:21582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79825.1"
                     /translation="CQQNSNWHLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcaacttag cctggtacca gcagagacct gggcagtctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcatctcac tttcggtgga gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002301             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17169:11969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002301
VERSION     KCVT01002301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17169:11969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79826.1"
                     /translation="CQQYFSSPFTF"
     J_segment       385..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT           96 a          128 c          108 g           93 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caaattatat tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagcag tattttagct ccccattcac tttcggcccc gggaccaaac tggatatcag
      421 acgag
//
LOCUS       KCVT01002302             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10704:8422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002302
VERSION     KCVT01002302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10704:8422"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79827.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           91 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002303             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19937:13764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002303
VERSION     KCVT01002303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19937:13764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79828.1"
                     /translation="CQQYDSFPFTS"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          100 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatac aaatcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatagtttt ccattcactt ccggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002304             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9180:6159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002304
VERSION     KCVT01002304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9180:6159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..246
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79829.1"
                     /translation="CQQYDSDPFTF"
     J_segment       249..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           75 a           69 c           80 g           63 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg tcgggcgagt cagggcattc gcagttattt
       61 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccag
      121 tttggaaagt ggggtcccat caaggttcag cggcggtgga tctgggacag aattcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      241 tgacccgttc actttcggtg gagggaccaa ggtagacatc aaacgag
//
LOCUS       KCVT01002305             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7041:13529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002305
VERSION     KCVT01002305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7041:13529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79830.1"
                     /translation="CIQALEFPWTF"
     J_segment       282..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           73 a           82 c           88 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccac aactcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      241 gatgttgggg tttattactg cattcaagct ctagagtttc cgtggacgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002306             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14826:10845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002306
VERSION     KCVT01002306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14826:10845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79831.1"
                     /translation="CQQYNSLPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          109 c          112 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattgag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcgttaa cgtttattta aattggtatc agcagaaacc ggggaaagcc cctaagcccc
      241 tgatctttta tgcaaaccgt ttggaacgtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaagttatt
      361 attgtcaaca gtataatagt ttaccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002307             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18513:3821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002307
VERSION     KCVT01002307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18513:3821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79832.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          117 c          110 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cctattactg
      361 tcaacagtat gacagtgatc cgttcacttt cggtgggggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01002308             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21648:7485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002308
VERSION     KCVT01002308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21648:7485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..288
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <266..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79833.1"
                     /translation="CMQALEFPLTF"
     J_segment       289..326
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>329
                     /gene="IGKC"
BASE COUNT           77 a           83 c           93 g           76 t
ORIGIN      
        1 acatgggcca ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc
       61 aagtcagagc ctcctggata gtgaggatgg aaacacctat ttgcactggt acttgaagaa
      121 gccaggccag tctccacagg tcttaattta tgaggtttcc aaccgggcct ctggagtccc
      181 agacaggttc agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga
      241 ggctgaggat gttggggttt attactgcat gcaagctcta gagtttccgc tcactttcgg
      301 tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002309             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10246:3921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002309
VERSION     KCVT01002309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10246:3921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79834.1"
                     /translation="CQQYNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagta taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002310             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11781:19129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002310
VERSION     KCVT01002310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11781:19129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79835.1"
                     /translation="CQQNSSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          118 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtagc tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002311             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:7152:11350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002311
VERSION     KCVT01002311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7152:11350"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79836.1"
                     /translation="CLQFKSYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          104 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagctt ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagagtat
      181 tagtactcat ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa agttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002312             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21986:6118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002312
VERSION     KCVT01002312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21986:6118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79837.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tgtattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002313             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19781:17344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002313
VERSION     KCVT01002313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19781:17344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79838.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          118 c          102 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaaccccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacaat ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01002314             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7487:10881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002314
VERSION     KCVT01002314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7487:10881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79839.1"
                     /translation="CQQHADSPRTF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          117 c          108 g           88 t
ORIGIN      
        1 acatgggagt ctcagacagg acacagcatg gacacgaggg tccccgctca gctcctgggg
       61 ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag tcagggtatt
      181 agcaactggt tggcctggta tcaacagaga ccagggaaag cccctaaggt cctgatttat
      241 aggacatcca atttggaaac aggggtccca tcaaggttca gtggaaccgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatt tcgctacata ttactgtcaa
      361 cagcatgctg attcccctcg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01002315             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15746:14848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002315
VERSION     KCVT01002315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15746:14848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79840.1"
                     /translation="CQQYDSDTRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac acgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002316             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19994:17703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002316
VERSION     KCVT01002316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19994:17703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79841.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          115 c           98 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01002317             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15601:6793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002317
VERSION     KCVT01002317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15601:6793"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79842.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccttgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002318             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6041:12299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002318
VERSION     KCVT01002318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6041:12299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79843.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 aaaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002319             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:13510:14747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002319
VERSION     KCVT01002319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13510:14747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79844.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          113 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtt tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002320             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17265:5246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002320
VERSION     KCVT01002320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17265:5246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79845.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          123 c          119 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagcg tagcctggta ccagcagaaa cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggaggt
      421 caaacgag
//
LOCUS       KCVT01002321             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5117:7576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002321
VERSION     KCVT01002321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5117:7576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..389
                     /note="immunoglobulin light chain variable region"
     V_region        50..389
     V_segment       50..351
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79846.1"
                     /translation="CMQPLEFPWTF"
     J_segment       352..389
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>392
                     /gene="IGKC"
BASE COUNT           87 a          100 c          113 g           92 t
ORIGIN      
        1 acatgggctc ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat
       61 gacccagact ccactgtccc tgcccgtcac ccttggagag ccggcctcca tctcctgtgg
      121 gtctagtcag agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca
      181 gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt
      241 cccagacagg ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt
      301 ggaggctgag gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt
      361 cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002322             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15755:10490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002322
VERSION     KCVT01002322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15755:10490"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..375
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79847.1"
                     /translation="CQQGYSYPYSF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          119 c          107 g           96 t
ORIGIN      
        1 acatggggtc agtctcagtc aggacacagc atggacatga gggtccccgc tcagctcctt
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac gcagtctcca
      121 tcctccctgt ccgcatctgc aggagacaca gtcaccatca cttgccaggc gagtcaaggc
      181 attggcaata ctttaaattg gtatcaacag aaaccgggga aagcccctac actcctgatc
      241 tatagggcat ccggtttgca aagtgggact ccctctcggt tcagcggcag tggatctggg
      301 acggatttca ctctcaccat cagcagcctg cagcctgaag attttgccac ttattactgt
      361 caacagggtt atagttatcc gtacagtttt ggccagggga ccaaactgga gatcaaacga
      421 g
//
LOCUS       KCVT01002323             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4084:17221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002323
VERSION     KCVT01002323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4084:17221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79848.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggaggc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002324             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15009:17042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002324
VERSION     KCVT01002324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15009:17042"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79849.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          119 c          106 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg atccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002325             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:17066:8639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002325
VERSION     KCVT01002325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17066:8639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79850.1"
                     /translation="CMQPLEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tccttaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagcctg
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002326             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18083:16738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002326
VERSION     KCVT01002326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18083:16738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79851.1"
                     /translation="CGQGTHLPLTF"
     J_segment       390..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g           94 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtccagtca aagccttgta
      181 tacatcactg gaaacacata cttgagttgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggatt
      361 tattactgcg ggcaaggtac acaccttccg ctcactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01002327             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20552:15005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002327
VERSION     KCVT01002327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20552:15005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79852.1"
                     /translation="CQQYDSDPLTF"
     J_segment       348..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           92 a          107 c          100 g           89 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcagggcatt cgcagttatt tagcgtggta tcagcagaaa
      181 ccagggaaag tcccgaagcc cttgatctat tacgcgtcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcaa cagtatgaca gtgacccgct cactttcggt
      361 ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01002328             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16066:10434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002328
VERSION     KCVT01002328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16066:10434"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..346
                     /note="immunoglobulin light chain variable region"
     V_region        63..346
     V_segment       63..308
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <286..>318
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79853.1"
                     /translation="CMQALEFPWTF"
     J_segment       309..346
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        347..>349
                     /gene="IGKC"
BASE COUNT           84 a           87 c           96 g           82 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccagactc
       61 cactccatct cctgcaggtc tagtcagagt ctcttggata gtgaggatgg aaacacctat
      121 ttggaatggt acctgcagaa gccaggccag tctccacagc tcttgattta tgaggtttcc
      181 aaccgggcct ctggagtccc agacaggttc agtggcggtg ggtcagacac tgatttcaca
      241 ctgaaaatca gcagagtgga ggctgatgat gttggggttt attactgcat gcaagctcta
      301 gagtttccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002329             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8846:19890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002329
VERSION     KCVT01002329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8846:19890"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..284
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79854.1"
                     /translation="CLQFKTYPLTF"
     J_segment       285..322
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           84 a           79 c           79 g           83 t
ORIGIN      
        1 acatgggaga tgactcagtc tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc
       61 atcacttgtc gggcaggtca ggatattagc agttatttaa gttggtttca gcagaaacca
      121 gggaaagccc ctaaactcct gatctatgct gcgtccagtt tggaaagtgg ggtcccatca
      181 aggttcagcg gcagtgagtc tgggacagaa ttcactctca ccatcagcag cctacagcct
      241 gaagattttg cgacttatta ctgtctacaa tttaaaactt acccgctcac tttcggtgga
      301 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002330             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19473:11884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002330
VERSION     KCVT01002330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19473:11884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79855.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          121 c          118 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagcaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagaggcac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcgggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002331             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15201:11545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002331
VERSION     KCVT01002331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15201:11545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..375
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79856.1"
                     /translation="CLQYKSYAFSF"
     J_segment       378..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          106 a          108 c          102 g          102 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tgaagttatt
      181 atcaattatt taaattggtt tcagcagaaa ccagggaaag cccctaagct cctgatttat
      241 ggtgcatcca ggttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaagtta ttactgtctg
      361 cagtataaaa gttacgcatt cagtttcggc cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01002332             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15931:18781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002332
VERSION     KCVT01002332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15931:18781"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79857.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002333             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24102:17089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002333
VERSION     KCVT01002333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24102:17089"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79858.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002334             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5636:8508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002334
VERSION     KCVT01002334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5636:8508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79859.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           94 a          125 c          120 g           94 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccact ggggatgttg tgatgactca gtctccgctc
      121 tccctgccca tcacccctgg acagccggcc tccgtctcct gcaggtctag tcaaagcctt
      181 gtgcacagcg atggaaacac atacttgact tggtatcaac agaagccagg ccaacctcca
      241 aggcgcctaa tttttgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga cgatgttggg
      361 gtttattact gcggccaagg tacacacctt ccgtggacgt tcggccaagg gaccacggtg
      421 gaactcaaac gag
//
LOCUS       KCVT01002335             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23611:3338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002335
VERSION     KCVT01002335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23611:3338"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79860.1"
                     /translation="CQQYNTLPLTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          110 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatacttta ccgttgacgt tcggccaagg gaccaaggtg gaaatcaaag
      421 gag
//
LOCUS       KCVT01002336             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24091:9576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002336
VERSION     KCVT01002336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24091:9576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79861.1"
                     /translation="CQQYDSDTRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          115 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acacgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002337             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16827:10275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002337
VERSION     KCVT01002337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16827:10275"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..317
                     /note="immunoglobulin light chain variable region"
     V_region        120..317
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79862.1"
                     /translation="CMQSLDFPLTF"
     J_segment       282..317
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>322
                     /gene="IGKC"
BASE COUNT           70 a           84 c           86 g           82 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcaccagagt ggaggctgag
      241 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      301 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01002338             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12539:13045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002338
VERSION     KCVT01002338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12539:13045"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79863.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002339             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:23010:12636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002339
VERSION     KCVT01002339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23010:12636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79864.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          118 c          121 g          108 t
ORIGIN      
        1 atggggtgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcttgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tctggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002340             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14796:6992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002340
VERSION     KCVT01002340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14796:6992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79865.1"
                     /translation="CQQYNSLPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          121 c          100 g           98 t
ORIGIN      
        1 acatggggag tcagacccag ccaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cgttcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaatac ttatttaaat tggtatcagc agaaaccggg gacagcccct aagctcctga
      241 tctattatgc aaaccgtttg cacagtgggg tcccatcaag agtcagcggc agcggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttatttct
      361 gtcaacagta taattcttta ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002341             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10801:11930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002341
VERSION     KCVT01002341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10801:11930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79866.1"
                     /translation="CHQGNRIPPYNF"
     J_segment       392..429
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          104 a          119 c          108 g          101 t
ORIGIN      
        1 acatggggac gtttagcctg tgacagggct cagctaacat aatggatttt caggctcaaa
       61 ttttcatctt ccttctgctc agtgtcacag tgtccagcgg agaaattgtg ctgacccagt
      121 ctccgacatc cttggctgtc tcccagggag agagggtcac catctcctgc acggccagct
      181 caagcgtaag taccagctac gtgcactggt accaacaaaa gccaggattc cctccaaggc
      241 ttcttgtctt tagaacgtca agtctggctt ctggggtccc agccaggttc agtggcagcg
      301 gttctggggc ctcttacacg ctcacaatca gcaccatgga ggctgaagat gctgcaaact
      361 attactgtca ccaggggaat cgcattccac cgtacaattt tggccagggg accaaactgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01002342             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8739:7405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002342
VERSION     KCVT01002342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8739:7405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79867.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          123 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagaatc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01002343             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16848:9614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002343
VERSION     KCVT01002343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16848:9614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79868.1"
                     /translation="CMQSIKDPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          101 a          121 c          110 g          107 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tccagtgggg atattgtgat gacccagacc
      121 ccactctcgg tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctcc atagtaatgg agacacctat ttacattggt accttcagag gtcaggccag
      241 tctccacggc tcctgatcta taaagtaacc aatcggctac ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 attggtgttt atttctgcat gcaaagtata aaagatccat tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01002344             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18083:16401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002344
VERSION     KCVT01002344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18083:16401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79869.1"
                     /translation="CMQSLEIPPTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           92 a          120 c          122 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtggggatgg aaacacctat ttggattggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagccac tgatttcaca ctgaaaatca gcagggtgga ggctgaggat
      361 gttggggttt attactgcat gcaatctcta gagattcctc ccactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01002345             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9252:13199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002345
VERSION     KCVT01002345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9252:13199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79870.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002346             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18270:7503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002346
VERSION     KCVT01002346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18270:7503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79871.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaaatggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002347             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10068:7862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002347
VERSION     KCVT01002347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10068:7862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79872.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          121 c          118 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atattggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002348             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9201:7879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002348
VERSION     KCVT01002348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9201:7879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79873.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          112 c          111 g          100 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattat
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002349             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18978:15300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002349
VERSION     KCVT01002349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18978:15300"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79874.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc tacttatttc
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002350             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4623:14823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002350
VERSION     KCVT01002350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4623:14823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79875.1"
                     /translation="CMQALDFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcggtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagactt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002351             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10837:7897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002351
VERSION     KCVT01002351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10837:7897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79876.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01002352             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:9653:6926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002352
VERSION     KCVT01002352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9653:6926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79877.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          104 t
ORIGIN      
        1 acagggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002353             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17113:18800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002353
VERSION     KCVT01002353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17113:18800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79878.1"
                     /translation="CQQNSNWPRTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          125 c          113 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctcgca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002354             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6961:22555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002354
VERSION     KCVT01002354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6961:22555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79879.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          125 c          111 g           86 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcttagcctg gtaccaacaa aaacctgggc aggctcccag gctcctcatc
      241 tatggtgcat ccagcagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagacttca ctctcaccat caccagcctg gagcctgaag atgttgcagt ctatttttgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01002355             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14190:19156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002355
VERSION     KCVT01002355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14190:19156"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    161..331
                     /note="immunoglobulin light chain variable region"
     V_region        161..331
     V_segment       161..293
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79880.1"
                     /translation="CLQGYITPYSF"
     J_segment       294..331
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           76 a           91 c           91 g           76 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catccagttt gcaaagtggg
      181 gtcccgtcaa ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc
      241 ctgcagcctg aagattttgc ggcttattat tgtctacagg gttatattac cccgtacagt
      301 tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01002356             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10313:11770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002356
VERSION     KCVT01002356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10313:11770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79881.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          123 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgcaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002357             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23606:8601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002357
VERSION     KCVT01002357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23606:8601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79882.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          115 c          112 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 ggatattaac aactggttgg cctggtatca acagaaacca gggaaagccc ctaaggtcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cgcctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002358             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:27106:7830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002358
VERSION     KCVT01002358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:27106:7830"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79883.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002359             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10263:5153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002359
VERSION     KCVT01002359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10263:5153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79884.1"
                     /translation="CQQYNTLPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          109 c          107 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaga tatttaaatt ggtatcagca gaaaccgggg aaagccccta agttcctgat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattattg
      361 tcaacagtat aatactttac cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002360             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18835:9922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002360
VERSION     KCVT01002360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18835:9922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79885.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          109 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct ctgggggaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002361             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15335:11060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002361
VERSION     KCVT01002361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15335:11060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79886.1"
                     /translation="CLQYKSYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          115 c          108 g          101 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gcccgatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcttc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 ggtcttagca gttctttaca ttggtttcaa cacaaaccag ggaaagcccc taggctcctg
      241 atctatgctg catccagttt ggcaggtggg gtcccattaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagaagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaagtta cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002362             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14797:11154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002362
VERSION     KCVT01002362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14797:11154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79887.1"
                     /translation="CQQGNSNPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          104 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt catatgtccc agtctccgtc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctgaac tcctgatctt
      241 ttatacaaac actttggcaa gtggggtccc atcacggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagggtaat agtaatccgt tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01002363             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:15094:14750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002363
VERSION     KCVT01002363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15094:14750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79888.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          118 c          120 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcatgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tgtggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002364             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19430:17848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002364
VERSION     KCVT01002364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19430:17848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79889.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccattctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccaggcagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggagactgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01002365             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20590:14896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002365
VERSION     KCVT01002365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20590:14896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79890.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002366             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10582:4832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002366
VERSION     KCVT01002366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10582:4832"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79891.1"
                     /translation="CLQFKSYPNSF"
     J_segment       380..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          102 a          117 c          101 g           98 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcttg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctatctg catctgtagg agacactgtc accatcactt gccgggcaag tcagagtctt
      181 accactcatt taagttggtt tcagcagaaa ccagggaaag cccctaagct cctcatctat
      241 gctgcatcca gtttggccgg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtttaaaa gttacccgaa cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01002367             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19734:14289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002367
VERSION     KCVT01002367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19734:14289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79892.1"
                     /translation="CQQGKSNPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          115 c          112 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgtcccagt
      121 ctccatcctc cctgtctgca tccgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattag tgattcttta aattggtatc aacagaaacc ggggaaagcc cctaagctcc
      241 tgatctttta tgcaaacact ttggcaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagta gcctgcagcc tgcagatctt gcgacttatt
      361 actgtcaaca gggtaaaagt aatcctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002368             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:27139:18480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002368
VERSION     KCVT01002368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:27139:18480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79893.1"
                     /translation="CQQGYSYHPTF"
     J_segment       382..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT           94 a          119 c          107 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacttc cttatgacgc agtctccttc
      121 ctccctgtcc acatctgtag gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tggcactaat ttaaattggt atcagcagag accaggaaaa gcccctaaac tcctgatcta
      241 tagggcttcc ggtttgcaga gtgggactcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcagt ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttaccatc ccactttcgg cggagggacc aaggtggaga tccaacgag
//
LOCUS       KCVT01002369             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13590:18233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002369
VERSION     KCVT01002369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13590:18233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79894.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gaccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002370             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7918:6588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002370
VERSION     KCVT01002370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7918:6588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..314
                     /note="immunoglobulin light chain variable region"
     V_region        9..314
     V_segment       9..272
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79895.1"
                     /translation="CQQYDSDSLTF"
     J_segment       277..314
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>317
                     /gene="IGKC"
BASE COUNT           81 a           80 c           81 g           75 t
ORIGIN      
        1 acatggggag tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg
       61 tcgggcgact caggacattc gcagttattt agcgtggtat cagcagaaac cagggaaagc
      121 cccgaagccc ttgatctatt acgcgtccac tttggaaagt ggggtcccat caaggttcag
      181 cggcagtgga tctgggacag aattcactct caccatcaac agccttcagc ctgaagattt
      241 tgcaacttat tactgtcaac agtatgacag tgattcgctc actttcggtg gagggaccaa
      301 ggtggagatc aaacgag
//
LOCUS       KCVT01002371             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11941:16190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002371
VERSION     KCVT01002371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11941:16190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79896.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcattggcag tgggtcagac acagatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaccga g
//
LOCUS       KCVT01002372             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15009:10487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002372
VERSION     KCVT01002372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15009:10487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79897.1"
                     /translation="CLQGYSAPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          119 c          104 g           97 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctacttcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttacttaagt tggtatcagc agaaaccagg aaaaactcct cagcgcctga
      241 tctatgctgc atccagtttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgct gcttattact
      361 gtctacaggg ttatagtgcc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002373             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23134:12399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002373
VERSION     KCVT01002373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23134:12399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79898.1"
                     /translation="CLQGDTAPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g           94 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggcaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattaa cgattattta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcagcttatt
      361 actgtctaca gggtgatact gccccgttca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002374             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21023:17604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002374
VERSION     KCVT01002374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21023:17604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79899.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          113 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct attttgattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002375             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6529:13631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002375
VERSION     KCVT01002375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6529:13631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79900.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          118 c          107 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002376             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4884:14675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002376
VERSION     KCVT01002376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4884:14675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79901.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca gcttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002377             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18524:7630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002377
VERSION     KCVT01002377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18524:7630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79902.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggagc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002378             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22481:9671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002378
VERSION     KCVT01002378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22481:9671"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79903.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          118 c          120 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcatgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tgtggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002379             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13368:3622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002379
VERSION     KCVT01002379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13368:3622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79904.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          112 c          102 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002380             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7332:14761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002380
VERSION     KCVT01002380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7332:14761"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79905.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaatcacct acttggaatg gtatttacag aagccaggcc
      241 agtctccgca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002381             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12014:8782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002381
VERSION     KCVT01002381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12014:8782"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79906.1"
                     /translation="CQHGYGIPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagcat ggacatgagg gcccccactc agctcctggg
       61 gttcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccaggcga gtcaggccat
      181 tagtaataat gtaatctggt atcagcagga accggggaaa gcccctaagc tcctgatcta
      241 taaggcatcc actttacaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 gcatggttat ggtatcccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002382             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18481:19376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002382
VERSION     KCVT01002382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18481:19376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79907.1"
                     /translation="CQHYSGLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          109 c          111 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacagttat ttaaattggt atcagcagag accggggaaa gcccctaagg tcctgatgtt
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcgactt attactgtca
      361 acactatagt ggtttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002383             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17950:15231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002383
VERSION     KCVT01002383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17950:15231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79908.1"
                     /translation="CQQYNSLPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          103 a          106 c          100 g           95 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccgtcctccc tgtctgcttc
      121 tgtgggagac agagtcacca tcagttgccg ggcaagtcag gacattatca gttatttaaa
      181 ttggtatcac cagaaaccgg ggaaagcccc taagctcctg atcttttata caaaccgttt
      241 ggaaactggg gtcccaccaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcaccagc ctacaacctg aagaatttgg aacttattac tgtcaacagt ataatagttt
      361 accgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01002384             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8825:13473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002384
VERSION     KCVT01002384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8825:13473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..419
                     /note="immunoglobulin light chain variable region"
     V_region        102..419
     V_segment       102..380
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79909.1"
                     /translation="CQQGYSYHPTF"
     J_segment       389..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>426
                     /gene="IGKC"
BASE COUNT           95 a          120 c          111 g          100 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tccttgggct cctgctgctc tggctcccag gtgccagatg tgacttcctt atgacgcagt
      121 ctccttcctc cctgtccgca tctgtaggag acacagtcac catcacttgc caggcgagtc
      181 aagccattgg cactaattta aattggtatc agcagagacc aggaaaagcc cctaaactcc
      241 tgatctatag ggcttccggt ttgcagagtg ggactccctc tcggttcagc ggcagtggat
      301 ctgggacgga tttcagtctc accatcagca gcctgcagcc tgaagatttt gccacttatt
      361 actgtcaaca gggttatagt taccatccca ctttcggcgg agggaccaag gtggagatcc
      421 aacgag
//
LOCUS       KCVT01002385             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20367:14326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002385
VERSION     KCVT01002385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20367:14326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79910.1"
                     /translation="CIQSLEFPWTF"
     J_segment       407..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          110 t
ORIGIN      
        1 acatgggggg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccact ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccttctcct gtaggtctag
      181 tcacagcctc ttggatagtg aggatggaaa tatccatttg gattggtatc tgcagaagcc
      241 aggccagtct ccacacctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggtttagt ggcagtgggt cagacactga tttcacactg aaaatcagca gggtggaggc
      361 tgaggatgtt ggggtttact actgcataca atctctagag tttccttgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01002386             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13685:8084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002386
VERSION     KCVT01002386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13685:8084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79911.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcttggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggcgaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctatttcgc atccattttg gaaagtggcg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002387             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18020:8930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002387
VERSION     KCVT01002387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18020:8930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79912.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          117 g          107 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002388             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22127:13098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002388
VERSION     KCVT01002388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22127:13098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79913.1"
                     /translation="CQQYNRFPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          113 c          106 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagtag ttacttaaat tggtatcagc aaaagccggg gaaagcccca aagcccctga
      241 tctattatgc aaaccgtttg gaaaatggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca ctttattact
      361 gtcaacaata taataggttt cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002389             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7177:9891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002389
VERSION     KCVT01002389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7177:9891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79914.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          120 c          115 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tggccagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtagaaatca
      421 aacgag
//
LOCUS       KCVT01002390             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18112:19344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002390
VERSION     KCVT01002390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18112:19344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79915.1"
                     /translation="CQQGYSYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccctc
      121 ctccctgtcc gcatctgtag gagacgcagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt ttcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttacccgt ggacgttcgg ccaaggggcc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002391             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15536:8073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002391
VERSION     KCVT01002391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15536:8073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..423
                     /note="immunoglobulin light chain variable region"
     V_region        96..423
     V_segment       96..379
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79916.1"
                     /translation="CQQRNTHPYMYSF"
     J_segment       385..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           98 t
ORIGIN      
        1 acatggggga gacccagtct ggacgcagca tggacatcag ggtcctcgct cagcttctcg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagttgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatctc ttgtcgggca agtcaggaca
      181 ttagcagtta tctagcctgg tatcaacaga aaccagggaa agcccctaac ctcctgatct
      241 ataaggcgtc cagtttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aggctgaaga ttttgcagtt tattactgtc
      361 aacagcgtaa tactcacccg tacatgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002392             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22945:9369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002392
VERSION     KCVT01002392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22945:9369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..421
                     /note="immunoglobulin light chain variable region"
     V_region        98..421
     V_segment       98..381
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79917.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       391..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>428
                     /gene="IGKC"
BASE COUNT          100 a          116 c          111 g          101 t
ORIGIN      
        1 acatgggggt tagacccagt ctggacgcag catggacatc agggtcctcg ctcagcttct
       61 cgggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagttga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg caagtcagga
      181 cattggcaat tatttagcct ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctataaggcg tccagtttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcag tttattactg
      361 tcaacagcgt aatagttacc cgtacatgtg cagttttggc ccggggacca aagtggagat
      421 ccgacgag
//
LOCUS       KCVT01002393             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12463:8575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002393
VERSION     KCVT01002393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12463:8575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79918.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggctactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002394             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14937:17611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002394
VERSION     KCVT01002394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14937:17611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79919.1"
                     /translation="CQQSYTYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          106 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt atctccagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggattcc ctctcggttc accggtagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaggat tttgccactt attactgtca
      361 acagagttat acttacccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002395             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:3656:13567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002395
VERSION     KCVT01002395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3656:13567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79920.1"
                     /translation="RQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa actagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attaccgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002396             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9349:15789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002396
VERSION     KCVT01002396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9349:15789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79921.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcttg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atctggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002397             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13182:6260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002397
VERSION     KCVT01002397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13182:6260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..378
                     /note="immunoglobulin light chain variable region"
     V_region        57..378
     V_segment       57..335
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79922.1"
                     /translation="CQQHDNMPLTF"
     J_segment       341..378
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>381
                     /gene="IGKC"
BASE COUNT           95 a          102 c          101 g           83 t
ORIGIN      
        1 acatgggggc tcagctcctg gggctcctgt tgctctggct cccaggtgcc agatgtgaca
       61 tccagatgac ccagtctcca tcctccctgt ctgcatctgt gggagacaga gtcaccatca
      121 cttgcagagc cagtcagggt attagcaact ggttggcctg gtatcaacag aaaccaggga
      181 aagcccctaa gctcctgatc tatagggcat ggaatctgga aacaggggtc ccatcaaggt
      241 tcagtggaag tggatccggg acagatttca ctctcaccat cagcagcctg cagcctgaag
      301 atttcgcaac atattactgt caacagcatg ataatatgcc gctcactttc ggtggaggga
      361 ccaaggtgga catcaaacga g
//
LOCUS       KCVT01002398             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:19093:3527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002398
VERSION     KCVT01002398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19093:3527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79923.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcggctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002399             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16653:12312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002399
VERSION     KCVT01002399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16653:12312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79924.1"
                     /translation="CQQYFSSPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           96 a          128 c          109 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccacgc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agagctggta gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcaccctcac catcaacagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagctc cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01002400             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13307:7097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002400
VERSION     KCVT01002400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13307:7097"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79925.1"
                     /translation="CMQYIHMPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggg tccagtgggg atattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgaaga tggaaacacc tatttggatt ggtacctgca gaagccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcaatggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctggg
      361 gatgttgggg tttattactg catgcaatat atacacatgc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002401             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:23002:6010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002401
VERSION     KCVT01002401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23002:6010"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79926.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          125 c          113 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01002402             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:3369:10566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002402
VERSION     KCVT01002402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3369:10566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79927.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          109 c          108 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc agtctccacc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcaacagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002403             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20597:17242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002403
VERSION     KCVT01002403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20597:17242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79928.1"
                     /translation="CQQYNSLPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          107 c          108 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cttccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcagttt tttaaattgg tatcagcaga aaccggggaa agcccctaag gccctgatct
      241 attatgcaaa ccggttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aatctgaaga ttttgcaact tattactgtc
      361 aacagtataa tagtttaccg tacagttttg gccaggggac caaagtagag atcaaacgag
//
LOCUS       KCVT01002404             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7351:13984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002404
VERSION     KCVT01002404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7351:13984"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79929.1"
                     /translation="CHQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          128 c          110 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc accacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcacca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002405             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19827:12774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002405
VERSION     KCVT01002405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19827:12774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79930.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcggcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002406             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21044:4388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002406
VERSION     KCVT01002406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21044:4388"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79931.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002407             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12527:6802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002407
VERSION     KCVT01002407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12527:6802"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    55..391
                     /note="immunoglobulin light chain variable region"
     V_region        55..391
     V_segment       55..354
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79932.1"
                     /translation="CGQGTHIPWTF"
     J_segment       355..391
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT          105 a           92 c          114 g           83 t
ORIGIN      
        1 acatgggcag aagggagatg agggaggaga atggggtgta aaggatccag tggggatgtt
       61 gtgatgactc agtctccact ctccctgccc atcacccctg gacagccggc ctccatctcc
      121 tgcaggtcta gtcaaagtct tctacacacc aatggaaaca tattcttgag ttggtatcag
      181 cagaagccag gccaacctcc aaggcgccta atttttgagg tttctaaccg ggactctggg
      241 gtcccagaca gattcagcgg cagtggggca gggatagatt tcacactgaa aatcagcaga
      301 gtggaggctg aggatgttgg gatttattac tgcggacaag gaacacacat tccttggacg
      361 ttcggccaag ggaccaacgt ggaaatcaaa cgag
//
LOCUS       KCVT01002408             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12616:19969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002408
VERSION     KCVT01002408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12616:19969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..379
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79933.1"
                     /translation="CQQGYSYHPTF"
     J_segment       388..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>425
                     /gene="IGKC"
BASE COUNT           94 a          120 c          111 g          100 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacttcctta tgacgcagtc
      121 tccttcctcc ctgtccgcat ctgtaggaga cacagtcacc atcacttgcc aggcgagtca
      181 agccattggc actaatttaa attggtatca gcagagacca ggaaaagccc ctaaactcct
      241 gatctatagg gcttccggtt tgcagagtgg gactccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcagtctca ccatcagcag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatagtt accatcccac tttcggcgga gggaccaagg tggagatcca
      421 acgag
//
LOCUS       KCVT01002409             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22278:9638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002409
VERSION     KCVT01002409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22278:9638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79934.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctctaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002410             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18677:9043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002410
VERSION     KCVT01002410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18677:9043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79935.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaataccta tttggaatgg caccggcaga tgccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctgacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002411             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18777:18689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002411
VERSION     KCVT01002411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18777:18689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79936.1"
                     /translation="CQRYNSIPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          110 c          110 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgcg tctgtaggag acacagtcac cattacttgc cgggcaagtc
      181 agggcattag tagttattta aattggtatc agcagaaacc ggggaaagcc cctaaggtcc
      241 tcatctatta tacaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagta gcctgcaacc tgaggatttt gcaacttatt
      361 actgtcaacg gtataacagt ataccgtaca cttttggcct ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002412             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5415:6626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002412
VERSION     KCVT01002412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5415:6626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79937.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          122 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01002413             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10585:13345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002413
VERSION     KCVT01002413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10585:13345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79938.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          121 c          124 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002414             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20401:10717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002414
VERSION     KCVT01002414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20401:10717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79939.1"
                     /translation="CQQHNRYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatcgata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002415             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18063:4495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002415
VERSION     KCVT01002415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18063:4495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79940.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           84 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgct gacgcagtct
      121 ccagccaccc tgtctatgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga acagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002416             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:8960:7290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002416
VERSION     KCVT01002416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:8960:7290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79941.1"
                     /translation="CLHYNSDPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          108 c          106 g          102 t
ORIGIN      
        1 acatggggaa gttagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc tgtaagagac agagtcacct tcacttgcag ggcaagtcag
      181 ggcattacaa cttttttaaa ttggtgtcag cagaaatcag gaaaaactcc taagcgcctg
      241 atctgtgttg aatacagttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacaggtt tcactctcac catcagcagc ctgcagcctg aagattttac aacttattcc
      361 tgtcttcatt ataacagtga cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002417             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21550:10016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002417
VERSION     KCVT01002417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21550:10016"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79942.1"
                     /translation="CLQYKSFPYTF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          113 a          118 c           99 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtggg agacactgtc accatcactt gccggacaag
      181 tcaaggtatt accaattatt tacattggtt tcaacagaaa ccagggaaag cccctaaact
      241 cctgatctat gaaacatcca gtttgacaag tggggtccca tcaaggttca gcggcagcgc
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtataaaa gtttcccgta cacttttggc caggggacca aactggagat
      421 caaacgag
//
LOCUS       KCVT01002418             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:12672:13893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002418
VERSION     KCVT01002418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12672:13893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79943.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggtc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002419             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:13682:3043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002419
VERSION     KCVT01002419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13682:3043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..395
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79944.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          127 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tggtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctgtagtc ccagacaggt
      301 tcagtggcag tgggtcagac gctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttattactgc atgcaatctc tagagctccc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002420             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10589:11629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002420
VERSION     KCVT01002420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10589:11629"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79945.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          126 c          111 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002421             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24405:13204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002421
VERSION     KCVT01002421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24405:13204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..376
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79946.1"
                     /translation="CLQYKSYAFSF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          110 c          104 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcgtctgtag gagacactgt caccatcact tgccgggcaa gtcaggttat
      181 tatcaattat ttaaattggt ttcagcagaa accaggggaa gcccctaagc tcctgattta
      241 tggcgcatcc agattggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagac tttgcaagtt attactgtct
      361 acagtataaa agttacgcat tcagtttcgg ccccgggacc aaagtggata tcaaacgag
//
LOCUS       KCVT01002422             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8441:22926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002422
VERSION     KCVT01002422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8441:22926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79947.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002423             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13215:6325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002423
VERSION     KCVT01002423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13215:6325"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79948.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002424             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6488:5470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002424
VERSION     KCVT01002424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6488:5470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79949.1"
                     /translation="CLQYKSFPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          117 c           96 g           98 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtattaccaa ttatttacat tggtttcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatgaaac atccagtttg acaagtgggg tcccatcaag gttcagcggc agcgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagtttc ccgtacactt ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01002425             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14943:13995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002425
VERSION     KCVT01002425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14943:13995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79950.1"
                     /translation="CQHSFRTPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          106 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caatgtcact tgcagggcta gtgagagcgt
      181 tagcaccaaa ttacattggt atcagcagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttacaaa gtggggtccc atcaaggttc agcggcagtg gttctggaac
      301 acatttcact ctcaccatca gcagcctgca gcctgaagat gtcgcaactt tttactgtca
      361 gcatagtttt cgtaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002426             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10284:8447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002426
VERSION     KCVT01002426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10284:8447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79951.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggaa aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002427             270 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13360:18782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002427
VERSION     KCVT01002427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 270)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13360:18782"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..267
                     /note="immunoglobulin light chain variable region"
     V_region        8..267
     V_segment       8..225
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79952.1"
                     /translation="CQQYDSDSLTF"
     J_segment       230..267
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>270
                     /gene="IGKC"
BASE COUNT           70 a           65 c           73 g           62 t
ORIGIN      
        1 acatgggcac ttgtcgggcg actcaggaca ttcgcagtta tttagcgtgg tatcagcaga
       61 aaccagggaa agccccgaag cccttgatct attacgcgtc cactttggaa agtggggtcc
      121 catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc
      181 agcctgaaga ttttgcaact tattactgtc aacagtatga cagtgattcg ctcactttcg
      241 gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01002428             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14040:19204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002428
VERSION     KCVT01002428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14040:19204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..401
                     /note="immunoglobulin light chain variable region"
     V_region        99..401
     V_segment       99..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79953.1"
                     /translation="CQKYSSSPFTF"
     J_segment       383..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           85 a          120 c          106 g           90 t
ORIGIN      
        1 acatggggga gctgctcagt taggacccag agagaaccat ggaaatccca gctcagcttc
       61 tcttcctcct gctactgtgg ctcccaggta ccaccggaca agttattttg actcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcag cagcttagcc tggtaccagc agaaacctgg gcaggccccc agactcctcg
      241 tctatggtgc atccaggagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agattttgca gtgtattact
      361 gtcagaagta tagtagttcc ccattcactt tcggccccgg g
//
LOCUS       KCVT01002429             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:17030:4290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002429
VERSION     KCVT01002429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17030:4290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79954.1"
                     /translation="CQHSYDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          106 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagtccctg agctcctgat
      241 ctatgttgca tcgtctttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc accctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcatagt tatgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002430             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9023:3376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002430
VERSION     KCVT01002430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9023:3376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..340
                     /note="immunoglobulin light chain variable region"
     V_region        19..340
     V_segment       19..303
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <280..>312
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79955.1"
                     /translation="CQQYNSLPLTF"
     J_segment       304..340
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        341..>343
                     /gene="IGKC"
BASE COUNT           92 a           84 c           84 g           83 t
ORIGIN      
        1 acatggggtg ccagatgtga cattcagatg acccagtctc cgtcctccct gtctgcatct
       61 gtaggagaca gagtcaccat cacttgccgg gcaagtcagg acactagcat ttatttaaat
      121 tggtatcagc agaaaccggg gaaagcccct aaggtcctga tctattatgc aaaccgtttg
      181 gaaactgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc
      241 atcagcagcc tgcaacctga ggattttgca acttattact gtcaacagta taatagttta
      301 cctctcactt tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002431             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8107:10924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002431
VERSION     KCVT01002431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8107:10924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79956.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          123 c          116 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat agcaccggag aaatagtgct gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagt ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccaggca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga acagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002432             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18002:4657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002432
VERSION     KCVT01002432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18002:4657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79957.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactggaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002433             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5481:7571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002433
VERSION     KCVT01002433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5481:7571"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79958.1"
                     /translation="CQQYDSDSLTF"
     J_segment       378..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          102 a          115 c          108 g           93 t
ORIGIN      
        1 actggggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac tcaggacatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002434             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9587:3793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002434
VERSION     KCVT01002434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9587:3793"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79959.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          117 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctgttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagaat ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aattcaaacg ag
//
LOCUS       KCVT01002435             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18016:11410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002435
VERSION     KCVT01002435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18016:11410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79960.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           96 a          126 c          112 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg aaaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgctttcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002436             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:4276:9930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002436
VERSION     KCVT01002436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:4276:9930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79961.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatctca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002437             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20434:4624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002437
VERSION     KCVT01002437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20434:4624"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79962.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          124 c          115 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 ttggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002438             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9949:14159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002438
VERSION     KCVT01002438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9949:14159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79963.1"
                     /translation="CMQYRHIPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          120 c          114 g          110 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaagctc cctgctcagc
       61 tcctggggct gctaatgctc tggctctctg gttccagtgg ggatgttgtg atgacccaga
      121 ctccattctc cctgtccgtt agccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt gaatagtgaa gacggaaaca cctatttgga ttggtacctg cagaggccgg
      241 gccagtctcc acagcccttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aattaacaga gtggaggctg
      361 aggatgttgg gatttatatc tgcatgcaat atagacacat tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01002439             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13529:10697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002439
VERSION     KCVT01002439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13529:10697"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79964.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          125 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag gtaccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcttccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002440             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22316:10125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002440
VERSION     KCVT01002440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22316:10125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79965.1"
                     /translation="CIQGLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgacgatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaaa ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tacaaggtct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002441             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17645:14098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002441
VERSION     KCVT01002441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17645:14098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79966.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccgtc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002442             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25103:5367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002442
VERSION     KCVT01002442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25103:5367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79967.1"
                     /translation="CQQGHSYPWTF"
     J_segment       379..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT           98 a          115 c          110 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacatagt cacgatcact tgccagtcga gtctaggcat
      181 tggcaaattt ttaaattggt atcagcagaa accagggaaa gcccccaaac tcctgatcta
      241 tagggcatcc agtttgcaaa ctgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccgctt attactgtca
      361 acagggtcat agttacccgt ggacgttcgg ccaagggacc aaggtggaga tgaaacgag
//
LOCUS       KCVT01002443             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:25990:9569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002443
VERSION     KCVT01002443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25990:9569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..337
                     /note="immunoglobulin light chain variable region"
     V_region        16..337
     V_segment       16..300
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>309
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79968.1"
                     /translation="CQQYDKSPPTF"
     J_segment       303..337
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        338..>340
                     /gene="IGKC"
BASE COUNT           90 a           92 c           88 g           70 t
ORIGIN      
        1 acatgggcca gatgtgacat ccagatgacc cagtctccat cctccctgtc ctcatctgta
       61 ggagacaggg tcaccatcac ttgcagagcc agtcagggta tcagcaactg gttggcctgg
      121 tatcaacaga aaccagggag agcccctaac ctcctgatgt atagggcgtc caatttgcaa
      181 ggaggggtcc catcaaggtt cagaggaagt ggatctggga cagatttcac tctcaccatc
      241 agcagcctgc agcctgagga tgtcgctaca tattactgtc aacagtatga taagtcccct
      301 ccgacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01002444             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18770:10529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002444
VERSION     KCVT01002444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18770:10529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79969.1"
                     /translation="CGQAIAFPLTF"
     J_segment       394..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           91 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgccc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatact aatggtaaca cctatttgca ctggtaccta cagaagccag gccagtctcc
      241 gcagctcctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcgacaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcggtcaag ctatagcgtt tccgctcact ttcggtggag ggaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01002445             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19016:10808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002445
VERSION     KCVT01002445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19016:10808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79970.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           89 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagccgg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002446             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5603:11252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002446
VERSION     KCVT01002446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5603:11252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79971.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          114 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttt ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002447             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19727:19218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002447
VERSION     KCVT01002447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19727:19218"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79972.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          120 c          108 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gttggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agagaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002448             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11599:8521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002448
VERSION     KCVT01002448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11599:8521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79973.1"
                     /translation="CQHSFRTPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          116 c          111 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcaat gtcacttgca gggctagtga
      181 gagcgttagc accaaattac attggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcgtccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggaacagat ttcactctca ccatcagcag cctgcagcct gaagatgtcg caacttttta
      361 ctgtcagcat agttttcgta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002449             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15753:16186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002449
VERSION     KCVT01002449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15753:16186"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79974.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           94 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002450             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11811:10674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002450
VERSION     KCVT01002450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11811:10674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79975.1"
                     /translation="CLQYKNFPLSF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          112 c          105 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatgggcat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccaggtgtga catccagatg actcagtctc
      121 cgtcttccct gtctgcatct ctaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 atattaacag ttatttaaat tggtttcagc agaaaccagg gaaagcccct aagctcctga
      241 tctatggtgc atccagtttg gaaagtgagg tcccattaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttatttct
      361 gtctacagta taaaaatttc ccgctctctt tcggcggagg gaccagggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01002451             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11394:14273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002451
VERSION     KCVT01002451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11394:14273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79976.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagtaattat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 tttcgcatcc actttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002452             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:5988:15055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002452
VERSION     KCVT01002452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:5988:15055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79977.1"
                     /translation="CMQALEFPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          117 c          121 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcatcct tggagagccg gcctccatat cctgcacgtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attattgcat gcaagctcta gagtttccgc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01002453             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16387:11244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002453
VERSION     KCVT01002453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16387:11244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79978.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01002454             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22631:9040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002454
VERSION     KCVT01002454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22631:9040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79979.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002455             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18284:11631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002455
VERSION     KCVT01002455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18284:11631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..407
                     /note="immunoglobulin light chain variable region"
     V_region        86..407
     V_segment       86..364
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <347..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79980.1"
                     /translation="CQQGYGFPFTF"
     J_segment       370..407
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>410
                     /gene="IGKC"
BASE COUNT           96 a          115 c          101 g           98 t
ORIGIN      
        1 acatggggga ggacacagca tggacatgag ggtccccgct cagctccttg ggctcctgct
       61 gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat cctccctgtc
      121 cgcatctgta ggagacacag tcgcgatcac ttgcctggcg agtcaaggca ttggcaataa
      181 tttaaattgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct atacggcatc
      241 caatttacat ggtgggattc cctctcggtt cagcggcagt ggatctggga cggatttcac
      301 tctcaccatc aacagcctgc agcctgaaga ttttgccact tattactgtc aacagggtta
      361 tggttttcca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01002456             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14074:20173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002456
VERSION     KCVT01002456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14074:20173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79981.1"
                     /translation="CQQYDSDTRTF"
     J_segment       383..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          113 c          112 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacacgc gtactttcgg tggagggact aaggtggaga tcaaacgag
//
LOCUS       KCVT01002457             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10444:19292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002457
VERSION     KCVT01002457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10444:19292"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79982.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtcaagtca
      181 gagcctcctg gatagtgagg atggaaacac ctatttgcac tggtacttga agaagccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002458             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15478:17439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002458
VERSION     KCVT01002458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15478:17439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79983.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002459             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21024:13256
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002459
VERSION     KCVT01002459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21024:13256"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79984.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g          105 t
ORIGIN      
        1 acttgactga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002460             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18815:9803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002460
VERSION     KCVT01002460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18815:9803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79985.1"
                     /translation="CLQGYIDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          113 c          114 g           99 t
ORIGIN      
        1 acatgggggg gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtcggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttgcaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 actgtctaca gggttatatt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002461             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22474:18540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002461
VERSION     KCVT01002461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22474:18540"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79986.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           98 a          117 c          116 g          100 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcac tggggacact gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgtcttt ggaataagcc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 actcctgatt tatcaagcaa ccaataagga gattggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaacctgacg atgctgcgga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01002462             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9949:10019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002462
VERSION     KCVT01002462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9949:10019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79987.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgactcgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01002463             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20978:4331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002463
VERSION     KCVT01002463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20978:4331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..434
                     /note="immunoglobulin light chain variable region"
     V_region        102..434
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79988.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>444
                     /gene="IGKC"
BASE COUNT           97 a          123 c          122 g          102 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtaccagaca
      301 ggttcagtgg cagtgggtca gacactgctt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccagggt ggaacccaaa cgag
//
LOCUS       KCVT01002464             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16836:16150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002464
VERSION     KCVT01002464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16836:16150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79989.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          115 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aaggcattga
      241 tctattacgc gtccactttg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002465             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13654:3342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002465
VERSION     KCVT01002465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13654:3342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79990.1"
                     /translation="CQQYNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 ggacattacc aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag tataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002466             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5414:16110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002466
VERSION     KCVT01002466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5414:16110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..333
                     /note="immunoglobulin light chain variable region"
     V_region        3..333
     V_segment       3..295
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <273..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79991.1"
                     /translation="CMQPLQFPWTF"
     J_segment       296..333
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        334..>336
                     /gene="IGKC"
BASE COUNT           79 a           87 c           93 g           77 t
ORIGIN      
        1 acatgggcca gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct
       61 gtaggtctag tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc
      121 tacagaagcc aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg
      181 gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca
      241 gagtggaggc tgaggatgtt ggggtttatt actgcatgca acctctacag tttccgtgga
      301 cgttcggcca agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01002467             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14567:14674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002467
VERSION     KCVT01002467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14567:14674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79992.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcacaagcca
      241 ggccagtctc cagagctctt gatttatgag gtttccaagc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag attggaggct
      361 gaggatgttg ggctttatta ctgtatgcaa gctctagagt ttcctctcac tttcggcgga
      421 gggaccaagg tggaggtcaa acgag
//
LOCUS       KCVT01002468             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15994:9912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002468
VERSION     KCVT01002468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15994:9912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79993.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggataca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002469             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:29556:14223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002469
VERSION     KCVT01002469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:29556:14223"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79994.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          117 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaccgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgtcccaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct ctagagtttc cttggacgtt cggccagggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002470             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23185:17913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002470
VERSION     KCVT01002470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23185:17913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79995.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccaggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002471             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23010:9529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002471
VERSION     KCVT01002471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23010:9529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79996.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tcgtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtccgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01002472             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9761:7194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002472
VERSION     KCVT01002472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9761:7194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79997.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01002473             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20267:9643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002473
VERSION     KCVT01002473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20267:9643"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79998.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002474             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9304:18523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002474
VERSION     KCVT01002474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9304:18523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..379
                     /note="immunoglobulin light chain variable region"
     V_region        108..379
     V_segment       108..341
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV79999.1"
                     /translation="CQQYNSLPYIF"
     J_segment       342..379
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>382
                     /gene="IGKC"
BASE COUNT          101 a           96 c           98 g           87 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag agtcaccatc
      121 acttgccggg caagtcagga cattagcgtt tttttaaatt ggtatcagca gaaaccgggg
      181 aaagccccta aacccctgat ctattatgca aaccgtttgg aaagtggggt cccatcaagg
      241 ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct gcaacctgaa
      301 gattttgcaa cttattactg tcaacagtat aatagtttac cgtacatttt tggccagggg
      361 accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01002475             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12823:18907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002475
VERSION     KCVT01002475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12823:18907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80000.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggac ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002476             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14624:9622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002476
VERSION     KCVT01002476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14624:9622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80001.1"
                     /translation="CQQDYHWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagacatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcacctt aacctggtac caccagaagc ctgggcaggc tcccaagctc
      241 ctcatctatg gtccatccat cagggccagc ggcatcccag acaggttcag tggcagtggg
      301 tctggaacag aatttactct caccatcagc agcctggaga ctgaagatgt tggagtttat
      361 tactgtcagc aggattatca ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01002477             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21381:9059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002477
VERSION     KCVT01002477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21381:9059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80002.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01002478             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13179:4771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002478
VERSION     KCVT01002478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13179:4771"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80003.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002479             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20051:17902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002479
VERSION     KCVT01002479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20051:17902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80004.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          126 c          111 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tacatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002480             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24681:10185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002480
VERSION     KCVT01002480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24681:10185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80005.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           85 a          123 c          124 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cgctctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctacagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggggtccca gacaggttca
      301 gtgccagtgg gtcgggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01002481             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24162:10745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002481
VERSION     KCVT01002481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24162:10745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80006.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          122 c          117 g           85 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catgtatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002482             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22407:13152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002482
VERSION     KCVT01002482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22407:13152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..436
                     /note="immunoglobulin light chain variable region"
     V_region        102..436
     V_segment       102..398
                     /gene="IGKV2-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80007.1"
                     /translation="CMQTLQTPYSF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          103 a          111 c          116 g          109 t
ORIGIN      
        1 acatggggag atcagaactg ctcagttcac cttctcaaga tgaggttccc tgctcagttc
       61 ttggggctgt taatgctctg ggtacctgga tccagtgggg gtattgtgat gacccagact
      121 ccactctccc tgccagtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgatgg aaatacttat ttgtattggt acctacagaa gccagggcag
      241 cctccacggc tcctaattta tacactttcc aaccggttct ctggagtgcc agacaggttc
      301 agtggcagtg gatcaggcac agatttcaca ctgaaaatca gccgggtgaa ggctgaggat
      361 gtcggggttt attactgcat gcaaacttta caaactccgt acagttttgg ccaggggacc
      421 aaagtggaga tcaaacgag
//
LOCUS       KCVT01002483             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21068:2018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002483
VERSION     KCVT01002483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21068:2018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80008.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          117 c          102 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgaa gactttgcaa cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01002484             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8964:8838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002484
VERSION     KCVT01002484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8964:8838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80009.1"
                     /translation="CQHSFRTPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          118 c          108 g           96 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgtc ggagacagag tcaccgtcac ttgcagggct agtgagagcg
      181 ttgacaccaa attacattgg tatcaacaga aaccagggaa agcccctagg ctcctgatct
      241 ttgctgcgtc cactttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggaa
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact ttttactgtc
      361 agcatagttt tcgtaccccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01002485             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18073:6409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002485
VERSION     KCVT01002485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18073:6409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..441
                     /note="immunoglobulin light chain variable region"
     V_region        120..441
     V_segment       120..403
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80010.1"
                     /translation="CQQHDNAPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          114 a          120 c          122 g           88 t
ORIGIN      
        1 acatggggtc aacgcagagt acatggggga gtcagtctca gacaggacac agcatggaca
       61 cgagggtccc cgctcagctc ctggggctcc tgttgctctg gctcccaggt gccagatgtg
      121 acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac agagtcacca
      181 tcacttgcag agccagtcag agtattaacg actggttggc ctggtatcaa cagagaccag
      241 ggaaggcccc taagctcctg atctataggg catccaattt ggaaacaggg gtcccatcaa
      301 ggttcagtgg aagtggatct gggacagatt tcactctcag catcagcagc ctgcagcctg
      361 aagatatcgc aacatattac tgtcagcagc atgacaatgc cccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002486             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18315:20578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002486
VERSION     KCVT01002486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18315:20578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80011.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01002487             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20761:4599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002487
VERSION     KCVT01002487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20761:4599"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80012.1"
                     /translation="CMQPLEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ttccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgag gatggaaaca cttatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cattgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002488             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14106:9272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002488
VERSION     KCVT01002488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14106:9272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80013.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          119 c          104 g           90 t
ORIGIN      
        1 acatgggagt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggagt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002489             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13958:17522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002489
VERSION     KCVT01002489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13958:17522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80014.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgactcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01002490             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18463:10723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002490
VERSION     KCVT01002490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18463:10723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80015.1"
                     /translation="CQQYYDLFWTF"
     J_segment       385..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          118 c          115 g           91 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gatcccagat accgccggag aaattgtagt gacgcagtct
      121 ccagccaccc tgtctttgtc accaggggag acagccaccc tctcctgcag ggccagtgag
      181 tatattggca gccacttagc ctggtatcag cagaaacctg ggcaggctcc caagctcctt
      241 gtccgtagtg cagacttcag ggccactggc atcccagaca ggttcagtgg cagcgggtct
      301 aggacagagt tcactctcac cattaacagc ctggagcctg aagatgttgg agtttatcac
      361 tgtcagcagt attatgactt gttttggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002491             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13110:11469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002491
VERSION     KCVT01002491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13110:11469"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80016.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcatcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002492             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20874:9663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002492
VERSION     KCVT01002492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20874:9663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..445
                     /note="immunoglobulin light chain variable region"
     V_region        124..445
     V_segment       124..407
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80017.1"
                     /translation="CQQGSPFPWTF"
     J_segment       408..445
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT          112 a          117 c          116 g          103 t
ORIGIN      
        1 acatggggga ggctctttct ctgggatgtg gcatgagcaa aactgacaag tcaaggcagg
       61 aagatgttgt ctccatcaca actcattggg tttctgctgc tctgggttcc agcctccaag
      121 ggtgaaattg tgctgactca gtctccagcc tttcggtctg tgactctaaa ggagaaagtc
      181 accatcacct gccaggccag tcagagcatt ggtaatagct tacactggta ccagcagaaa
      241 ccggatcagt ctccaaagct cctcatcaaa tatgcttccc agtccatctc aggggtcccc
      301 tcaaggttca gtggcagtgg atctgggaca gatttcaccc tcaccatcaa cagcctggaa
      361 gctgaagatg ctgcgacgta ttactgtcag cagggaagtc ctttcccgtg gacgttcggc
      421 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01002493             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:8652:22129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002493
VERSION     KCVT01002493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:8652:22129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80018.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcctcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002494             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24570:7569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002494
VERSION     KCVT01002494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24570:7569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..377
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80019.1"
                     /translation="CQHSYGTLTWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          117 c          107 g           92 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgcgg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gggacagagt caccatcact tgcaggacaa gtgagaacgt
      181 taagaactat ttacattggt atcagcaaaa accagggaaa gccccaaggc tcctgatcta
      241 tgctgcatcc actttgcaaa gtggggtccc atcaaggttc accggcagtg gatctggggc
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 acatagttat ggtaccctca cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002495             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13979:13535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002495
VERSION     KCVT01002495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13979:13535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80020.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgttg gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002496             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7442:17541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002496
VERSION     KCVT01002496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7442:17541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80021.1"
                     /translation="CQQYNSDPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          116 c          103 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag taaccatcac ttgtcgggcg agtcaggaca
      181 taagaagtta tttagcgtgg tatcagcaga aaccaggcaa agccccgaag cccttgatct
      241 attacgcatc cgttttggaa agtggggtcc catcaaggtt cagtggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagtctgc agcctgagga ttttgcaact tattactgtc
      361 aacagtataa cagtgaccca ttcactttcg gccccgggac caaactggat accaaacgag
//
LOCUS       KCVT01002497             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18650:13539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002497
VERSION     KCVT01002497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18650:13539"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80022.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc actcttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa gatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002498             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22047:13575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002498
VERSION     KCVT01002498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22047:13575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..351
                     /note="immunoglobulin light chain variable region"
     V_region        74..351
     V_segment       74..312
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80023.1"
                     /translation="CQQYDSDLFTF"
     J_segment       316..351
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>354
                     /gene="IGKC"
BASE COUNT           87 a           92 c           97 g           78 t
ORIGIN      
        1 acatggggtc aggacacagc atggacatga gggtccccgc tcagctccta ggactcctgc
       61 tgctctgtct cccaggagac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca
      121 gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg
      181 cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat
      241 tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt
      301 atgacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002499             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19120:12195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002499
VERSION     KCVT01002499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19120:12195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80024.1"
                     /translation="CQQVHTNPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          103 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gccagaacat
      181 ttggagttat ttagcgtggt atgagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctacatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaactt attactgtca
      361 acaggttcat actaacccat tcactttcgg ccccgggacc aaactggaaa tcaaacgag
//
LOCUS       KCVT01002500             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16422:20082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002500
VERSION     KCVT01002500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16422:20082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80025.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agaccctctt ggatggtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002501             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18867:17603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002501
VERSION     KCVT01002501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18867:17603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80026.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagta ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002502             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17545:11656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002502
VERSION     KCVT01002502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17545:11656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80027.1"
                     /translation="CQQYNNLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          112 c          106 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cactcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaaaat ttatttgaac tggtatcagc agaaaccggg gaaagcccct aacctcctga
      241 tctattatgg aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatcag
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca tcttattact
      361 gtcaacagta taataattta ccgtggacat tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002503             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24832:8438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002503
VERSION     KCVT01002503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24832:8438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80028.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          112 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg cccccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcgt ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttgaccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002504             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10640:4060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002504
VERSION     KCVT01002504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10640:4060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..329
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80029.1"
                     /translation="CQQHDNSPPTF"
     J_segment       332..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           92 a          101 c           95 g           81 t
ORIGIN      
        1 acatgggggg gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc
       61 agtctccatc ctccctctct gcatctgtag gagacagagt caccatgact tgcagagcca
      121 gtcagggtat taacgactgg ttggcctggt atcaacagag accagggaaa gcccctaaac
      181 tcctgatcta tagggcgtcc aatttggata caggggtccc atcctggttc agtggaagtg
      241 gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat
      301 attactgtca acagcatgat aattcccctc cgacgttcgg ccaagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01002505             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:25268:17530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002505
VERSION     KCVT01002505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25268:17530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80030.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatatgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002506             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18219:12962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002506
VERSION     KCVT01002506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18219:12962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80031.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc tacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002507             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19934:3874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002507
VERSION     KCVT01002507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19934:3874"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80032.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          121 c          123 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt cgagtcagag
      181 cctcttggat ggtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagcca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002508             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22187:17453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002508
VERSION     KCVT01002508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22187:17453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80033.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          118 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctgttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagaatgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa ttcaaacgag
//
LOCUS       KCVT01002509             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:8810:15535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002509
VERSION     KCVT01002509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:8810:15535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80034.1"
                     /translation="CMQALDFPYSF"
     J_segment       405..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          117 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acagctcttg atttttgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactaatt tcacactgaa aatcagcagt gtggaggctg
      361 aggatgttgg ggtctattac tgcatgcaag ctctagactt tccttacagt tttggccagg
      421 ggaccacagt ggagattaaa cgag
//
LOCUS       KCVT01002510             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14048:6739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002510
VERSION     KCVT01002510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14048:6739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    139..457
                     /note="immunoglobulin light chain variable region"
     V_region        139..457
     V_segment       139..422
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <400..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80035.1"
                     /translation="CQQYFSSPFTF"
     J_segment       423..457
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>463
                     /gene="IGKC"
BASE COUNT          113 a          122 c          114 g          114 t
ORIGIN      
        1 acatgggggc ccagaaaaag caatcgttaa agctcaatat aaagcaataa ttctggctct
       61 actaggaaga cagtgggttt gatctgaatt acactgggtg acttttctgt tttatttcca
      121 atctcaggta ccaccggaca agttatattg actcagtctc cagccacgct gtctttgtct
      181 ccaggggaaa gagccaccct ctcctgcagg gccagtcaga gtgttggtag cagcttagcc
      241 tggtaccagc agaaacctgg gcaggccccc aggctcctca tctatggtgt atccagcagg
      301 gccactggca tcccagacag gttcagtggc agtgggtctg ggacagagtt cactctcacc
      361 atcagcagcc tggagcctga acattttgca gtgtattact gtcagcagta ttttagctcc
      421 ccattcactt tcggccccgg gaccaaactg gatatcagac gag
//
LOCUS       KCVT01002511             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7982:6563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002511
VERSION     KCVT01002511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7982:6563"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80036.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtaggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002512             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21013:12659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002512
VERSION     KCVT01002512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21013:12659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..343
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80037.1"
                     /translation="CQQYNSEPRTF"
     J_segment       351..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           92 a          108 c          101 g           87 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcagggcatt cgcagttatt tagcgtggta tcagcagaaa
      181 ccagggaaac ccccgaagcc cttgatctat tacgcgtcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcaa cagtataaca gtgagccgcg cactttcggt
      361 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002513             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:25045:9751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002513
VERSION     KCVT01002513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25045:9751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80038.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          118 c          114 g           90 t
ORIGIN      
        1 acatggggag agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg cgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002514             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24570:6309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002514
VERSION     KCVT01002514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24570:6309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80039.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggtt ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002515             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14313:7236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002515
VERSION     KCVT01002515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14313:7236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80040.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          122 c          116 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccag cagaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002516             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8244:15040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002516
VERSION     KCVT01002516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8244:15040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80041.1"
                     /translation="CQQGYGLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          119 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagtccca gtcaggacac agcatggaca tgagggcccc cactcagctc
       61 ctggggttcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtcttcatc tataggagac agagtcacca tcacttgcca ggcgaatcag
      181 gacattaaca atattttagc ctggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctatgagg catccacttt acaaagtggg gtcccatcac ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcagcaag gttatggtct cccgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01002517             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18851:10170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002517
VERSION     KCVT01002517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18851:10170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80042.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          117 c          125 g          104 t
ORIGIN      
        1 atggggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt tcctgcaggt cgagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cggtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002518             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10243:5330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002518
VERSION     KCVT01002518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10243:5330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80043.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          117 c          105 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01002519             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18399:13174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002519
VERSION     KCVT01002519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18399:13174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80044.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaag tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gttcctgctg aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002520             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22920:7947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002520
VERSION     KCVT01002520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22920:7947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80045.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          123 c          116 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ttgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag tagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002521             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18419:8276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002521
VERSION     KCVT01002521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18419:8276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..285
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80046.1"
                     /translation="CQQHDDSPRTF"
     J_segment       287..322
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           92 a           84 c           80 g           69 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc
       61 atcacttgca gagccagtca ggatattaac aactggttgg cctggtatca acagaaacca
      121 gggaaagccc ctaaggtcct gatctatagg gcatccattt tggaaacagg ggtcccatca
      181 aggttcagtg gaagtggatc tgggacagat ttcactctca ccatcagcag cctgcagcct
      241 gaagatatcg caacatatta ctgtcaacag catgatgatt cccctcggac gttcggccaa
      301 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002522             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:27370:14580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002522
VERSION     KCVT01002522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27370:14580"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80047.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          118 c          104 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gccagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002523             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17217:11643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002523
VERSION     KCVT01002523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17217:11643"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80048.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          101 a          118 c          118 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctcccta ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttagagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttaattt atgaggtttc ctaccgggcc tctggagtcc cagagaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002524             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24776:7493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002524
VERSION     KCVT01002524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24776:7493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80049.1"
                     /translation="CQQGYRYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          105 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcctctgtgg gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tgacattaat ttaaattact atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc cgtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat aggtacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002525             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23223:19339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002525
VERSION     KCVT01002525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23223:19339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80050.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ctaaggtgga gatcaaacga g
//
LOCUS       KCVT01002526             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25234:12188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002526
VERSION     KCVT01002526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25234:12188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80051.1"
                     /translation="CLQYKTYPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          111 c          109 g          101 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg cttctgtagg agacactgtc accatcactt gccgggcaag
      181 tcagggtatt gctggttatt taaattggtt tcagaagaaa ccagggaaag cccctaagct
      241 cctgatccaa gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgtaactta
      361 ttactgtcta cagtataaaa cttatccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01002527             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22178:12425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002527
VERSION     KCVT01002527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22178:12425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80052.1"
                     /translation="CQKYISSPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           97 a          130 c          105 g           91 t
ORIGIN      
        1 acatggggga gctgctcagt taggacccag agagaaccat ggaaatccca gctcagcttc
       61 tcttcctcct gctactgtgg ctcccaggta ccaccggaca acttatattg actcagtctc
      121 cagccaccct gtctctgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcag cagcttagcc tggtaccagc agaaacctgg gcaggccccc aggctcctcc
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agattttgca gtatattact
      361 gtcagaaata tattagctcc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002528             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12685:18405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002528
VERSION     KCVT01002528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12685:18405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80053.1"
                     /translation="CQQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          113 a          109 c          101 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 actcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacac
      181 aagtatttat ttaaattggt atcaacaaaa accggggaaa gcccctaagt tgctgatcta
      241 ttatggaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataac agtttaccgt acacttttgg ccacgggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002529             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13483:9070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002529
VERSION     KCVT01002529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13483:9070"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80054.1"
                     /translation="CQQHYGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          119 c          107 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc attatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002530             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15205:4476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002530
VERSION     KCVT01002530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15205:4476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80055.1"
                     /translation="CQQHADSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          118 c          112 g           89 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gggtattagc aactggttgg cctggtatca acagagacca gggaaagccc ctaaggtcct
      241 gatttatagg acatccaatt tggaaacagg ggtcccatca aggttcagtg gaaccggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg ctacatatta
      361 ctgtcaacag catgctgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002531             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15037:13118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002531
VERSION     KCVT01002531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15037:13118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80056.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002532             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8788:5967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002532
VERSION     KCVT01002532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8788:5967"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80057.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat tagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002533             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23808:12719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002533
VERSION     KCVT01002533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23808:12719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80058.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          111 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgcccgatg tgacatccag ctgacccagt
      121 ctccgtcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagtc
      181 agggtattaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaaactcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcggt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002534             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13276:16997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002534
VERSION     KCVT01002534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13276:16997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80059.1"
                     /translation="CLQGYNIPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          109 c          108 g           98 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagttgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc gcctgatcta
      241 tgctgtgtcc agtttggaat gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt attactgtct
      361 acagggttat aatatcccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002535             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:2891:15332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002535
VERSION     KCVT01002535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:2891:15332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..379
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80060.1"
                     /translation="CQQGYNYPWTF"
     J_segment       380..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          106 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatctct tgccgggcga gtcaaggcat
      181 tgacaataat ttaaattggt ttcaacagac accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcccgaagat tttgccactt attactgtca
      361 acagggttat aattacccgt ggacattcgg ccaagggacc aaggtggaaa tccaacgag
//
LOCUS       KCVT01002536             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15293:16145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002536
VERSION     KCVT01002536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15293:16145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80061.1"
                     /translation="CMQALEFPLIF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcattttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002537             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15264:14927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002537
VERSION     KCVT01002537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15264:14927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80062.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacaactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002538             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22460:12919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002538
VERSION     KCVT01002538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22460:12919"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80063.1"
                     /translation="CGQGTHLPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          100 a          123 c          119 g           92 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgatgactc agactccact
      121 ctccctgccc atcacccctg gacagccggc ctccatctcc tgcaggtcca gtcaaagcct
      181 tgtacacatc aatggacaca catacttgag ttggtatcag cagaagccag gccaacctcc
      241 aaggcgccta atttatgagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtgggaca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 gctttattcc tgcgggcaag gtacacacct tccgtggacg ttcggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01002539             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:9952:11704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002539
VERSION     KCVT01002539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9952:11704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80064.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          127 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttatgacc cagagggaac catggaagct ccagcacagc
       61 ttctcctcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002540             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:20181:5133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002540
VERSION     KCVT01002540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20181:5133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80065.1"
                     /translation="CMQALDFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtaatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cggtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002541             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5392:7581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002541
VERSION     KCVT01002541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5392:7581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80066.1"
                     /translation="CLQDVQLPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           86 a          123 c          122 g          108 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtggcg atattgtgat gactcagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctccttc atagtaatgg aaacacctat ttgttttggt acctgcagag gccaggccag
      241 tccccacagc tcctgatcta tttgggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgctt gcaagatgta cagcttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01002542             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:15556:3242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002542
VERSION     KCVT01002542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15556:3242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80067.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          102 t
ORIGIN      
        1 acatggggga ccacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002543             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20449:3050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002543
VERSION     KCVT01002543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20449:3050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80068.1"
                     /translation="CQQYSSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          107 c          112 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcataagtag ttatttaaat tggtatcaac agagaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcaggt tgcaacctga ggattttgca gtttattact
      361 gtcaacagta tagttcttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002544             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17711:6523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002544
VERSION     KCVT01002544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17711:6523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80069.1"
                     /translation="CLQDIQLPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           88 a          124 c          121 g          108 t
ORIGIN      
        1 acatggggtc tgatcaggac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctggggct gctggtgctc tggctccctg ggaccagtgg ggatattatg atgactcaga
      121 ctccactctc cctgtccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct gcataggaat gggtacacct atttgttttg gtacctgcag aagccaggcc
      241 agtctccaca gctcctgatc tatttcggtt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtgccag tgggtcaggc actgatttca cactgaaaat cagccgggtg gaggctgagg
      361 atgttggggt ttattactgc ttgcaagata tacaacttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002545             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20523:7793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002545
VERSION     KCVT01002545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20523:7793"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80070.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcactcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002546             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5558:8754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002546
VERSION     KCVT01002546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5558:8754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80071.1"
                     /translation="CLQTKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>455
                     /gene="IGKC"
BASE COUNT          101 a          124 c          122 g          108 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcagca gaaaccagga caacctccta
      241 aactcctggt ttatcaagca accaataggg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gcccgatttc accctcacta ttaatcctgt ggaacctgac gatgctgctg
      361 tttattactg tctgcagact aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaaca gcaaccaaga ttcattcatt gggag
//
LOCUS       KCVT01002547             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11267:9148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002547
VERSION     KCVT01002547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11267:9148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80072.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgagg cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacaatatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01002548             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16999:15459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002548
VERSION     KCVT01002548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16999:15459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80073.1"
                     /translation="CQQGDSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          111 c          111 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtctccttc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagagattat ttaaattggt atcagcagca accggggaaa gcccctaaac tcctgatgta
      241 ttatgcaaac agtctggcaa gtggagtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagggtgac agttatcctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002549             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:3009:11925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002549
VERSION     KCVT01002549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:3009:11925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80074.1"
                     /translation="CQQYDSDTRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          112 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggtga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacacgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002550             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12253:11569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002550
VERSION     KCVT01002550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12253:11569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80075.1"
                     /translation="CQQYNSLPFSF"
     J_segment       388..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          111 c          108 g          100 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccaattgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcct ctgtaggaga cagagtcacc atcacttgcc gggcaactca
      181 gggcattagc agttatttaa attggtatca gcataaaccg gggaaagccc ctgagctcct
      241 gatgtattat tcaaaccgtt tggagagtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ctgtcaacaa tataatagtt tgccgttcag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002551             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:3634:13151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002551
VERSION     KCVT01002551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3634:13151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80076.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct actcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002552             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12058:9132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002552
VERSION     KCVT01002552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12058:9132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80077.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt gatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002553             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8242:9396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002553
VERSION     KCVT01002553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8242:9396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80078.1"
                     /translation="CQQHADSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          118 c          111 g           89 t
ORIGIN      
        1 acatgggagg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gggtattagc aactggttgg cctggtatca acagagacca gggaaagccc ctaaggtcct
      241 gatttatagg acatccaatt tggaaacagg ggtcccatca aggttcagtg gaaccggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg ctacatatta
      361 ctgtcaacag catgctgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002554             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8810:20467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002554
VERSION     KCVT01002554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8810:20467"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80079.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaaatgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002555             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16446:15836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002555
VERSION     KCVT01002555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16446:15836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..366
                     /note="immunoglobulin light chain variable region"
     V_region        86..366
     V_segment       86..326
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80080.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       334..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           99 a           89 c           93 g           88 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca ggatggacat gacggtcccc gcttatctcc
       61 tggggctcct tctgctctgg ctcccaggag acaaagtcac catcacttgc agggcaagtc
      121 aggacattgg taattattta aattggtatc agcagaaacc aggaaaagct cctaaggtcc
      181 tgatctatgg tgtatccaat ttacaaagtg gggtcccatc aaggttcagc ggcagtggat
      241 ctgggacaga tcttactctc accatcagca gcctgcagcc tgaagatttt gcaacgtatt
      301 attgtcaaac gtttaaaagt tacctttcgg tccctttcgg cggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01002556             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:27512:9622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002556
VERSION     KCVT01002556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:27512:9622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80081.1"
                     /translation="CVQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaagt cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc gttcaagctc tagaatttcc gtggacgttc ggcccaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002557             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8172:14794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002557
VERSION     KCVT01002557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8172:14794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80082.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttagag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaggccag
      241 gccagtctcc acagctctta atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccagg
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002558             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:6887:20060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002558
VERSION     KCVT01002558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6887:20060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80083.1"
                     /translation="CMQGLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attctaatga cccagactcc
      121 gctctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggttg gagacaccta tttggagtgg tacctacaga agccaggcca
      241 gtctccgcat ctcttgattt atgaggtgtc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002559             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20137:12085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002559
VERSION     KCVT01002559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20137:12085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80084.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002560             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20255:12510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002560
VERSION     KCVT01002560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20255:12510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80085.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01002561             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13201:8153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002561
VERSION     KCVT01002561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13201:8153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80086.1"
                     /translation="CLQYKSFPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          112 c          103 g          102 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctacatc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gatattaaca gttatttaaa ttggtttcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagtctg aagattttgc aacttattac
      361 tgtctacaat ataaaagttt cccgctcact ttcggcggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01002562             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17375:10383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002562
VERSION     KCVT01002562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17375:10383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80087.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctggag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002563             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19373:14371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002563
VERSION     KCVT01002563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19373:14371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80088.1"
                     /translation="CQQGNSNPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          111 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgtcccagtt
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggccattagc agttatttaa attggtatca gcagaaaccg gggaaagccc ctaaactcct
      241 gatatactat ggaaaaagtt tggcaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcaccag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag ggtaatagta atcctctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002564             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8892:9480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002564
VERSION     KCVT01002564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8892:9480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80089.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggtatt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002565             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:26701:12488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002565
VERSION     KCVT01002565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26701:12488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80090.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002566             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14615:3351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002566
VERSION     KCVT01002566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14615:3351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80091.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgaa
//
LOCUS       KCVT01002567             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16404:15562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002567
VERSION     KCVT01002567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16404:15562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80092.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggaa
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002568             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16873:17025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002568
VERSION     KCVT01002568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16873:17025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80093.1"
                     /translation="CQQYDSDPFTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g           92 t
ORIGIN      
        1 atggggagac ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctaggac
       61 tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag tctccatcct
      121 ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgagt cagggcattc
      181 gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt
      241 acgcgtccac tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac
      361 agtatgacag tgacccgttc actttcggtg gagggaccaa ggtagagatc aaacgag
//
LOCUS       KCVT01002569             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18226:7892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002569
VERSION     KCVT01002569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18226:7892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80094.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          104 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactgtcc ctgcccgtca cccttggaga gccggcctcc atctcctgtg ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002570             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16699:19454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002570
VERSION     KCVT01002570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16699:19454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80095.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          113 c           98 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 ttccagttat ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgaaacatcc aatttggtaa ctggggtccc atcaaggttc agaggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcaacct attactgtct
      361 acagtataaa agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002571             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13518:12259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002571
VERSION     KCVT01002571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13518:12259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80096.1"
                     /translation="CVQALQIPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           92 a          117 c          123 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgcct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcacc cttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgag tagtaatgga tacagctatt tgagttggta cctgcagagg ccaggccagt
      241 ctccacatct tctgatctac tatggttcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgaaaatcag cagggtggag gctgaggacg
      361 taggggttta ttactgcgtg caagctctac aaattccgta cagttttggc caggggacca
      421 gagtggagat caaacgag
//
LOCUS       KCVT01002572             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:27977:8029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002572
VERSION     KCVT01002572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:27977:8029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80097.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca caccgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002573             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20689:12910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002573
VERSION     KCVT01002573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20689:12910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80098.1"
                     /translation="CQQYNSDPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          113 c          111 g           94 t
ORIGIN      
        1 acatggggca gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccaggtgacc cagtctccgt
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggcg
      181 ttagaagtta tttagcgtgg tatcagctga gaccatggaa agccccgaag gccttaatct
      241 attacgcgac cattttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgagga ttttgcaact tatttctgtc
      361 aacagtataa cagtgacccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01002574             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20749:3684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002574
VERSION     KCVT01002574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20749:3684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80099.1"
                     /translation="CMQALEFPLTF"
     J_segment       315..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           81 a           89 c          100 g           82 t
ORIGIN      
        1 acatgggggg acattgtgct gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcca tctcctgtag gtctagtcag agcctcttgg atagtgagga tggaaatacc
      121 tatttggaat ggcaccggca gatgccaggc cagtctccac agctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagtttc ctctgacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002575             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6975:3628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002575
VERSION     KCVT01002575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6975:3628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80100.1"
                     /translation="CLQSKNSPWSF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           96 a          117 c          117 g          100 t
ORIGIN      
        1 acatgggggc agcctctagt tcagctctca gaaatggggt cctgggctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggctgcact ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accttcacct gcagagccag tgggagtgtc
      181 agtgcctttg gaataagcct cattcactgg tatcagcaga aaccaggaca acctcctaaa
      241 ctcctgattt atcaagcaag caataaggag actggggtcc cagccaggtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aacctgacga tgctgcagat
      361 tattactgtc tgcagagtaa gaattctccg tggtcgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01002576             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10136:10528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002576
VERSION     KCVT01002576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10136:10528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..415
                     /note="immunoglobulin light chain variable region"
     V_region        101..415
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80101.1"
                     /translation="CQQYNTLPLTF"
     J_segment       385..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacacccaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaac atttatttaa attggtatca gcagaaaccg gggaaagccc ctgagctcct
      241 gatctattat gcaaaccgtt tggaaactgg ggtcccatca aggttcagcg gcggtggatc
      301 tgggacagaa ttcagtctca ccatcagcag cctgcaacct gaggactttg caacttatta
      361 ctgtcaacag tataatactt taccgctcac tttcggcgga gggaccaagg tggaggtcag
      421 acgag
//
LOCUS       KCVT01002577             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19364:6234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002577
VERSION     KCVT01002577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19364:6234"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80102.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           95 a          128 c          110 g           93 t
ORIGIN      
        1 acatgggaga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaggttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01002578             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14325:21121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002578
VERSION     KCVT01002578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14325:21121"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80103.1"
                     /translation="CMQGKEFPYSF"
     J_segment       404..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          119 c          124 g          102 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaagctc cctgctcagc
       61 tcctggggct gctaatgctc tggctccctg gatccagtgg ggatgttgtg atgacccaga
      121 ctccactctc cctgccagtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agaccctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaggccag
      241 gccagtctcc acagcccttg atttatgggg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag gcaaagagtt tccgtacagt tttggccagg
      421 ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01002579             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7177:19414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002579
VERSION     KCVT01002579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7177:19414"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80104.1"
                     /translation="CQHHNTYPHSF"
     J_segment       384..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          121 c          104 g           91 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattaccaat gatttagcct ggtatcagca gaaaccaggg aaagccccga ggcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaccat aatacttacc ctcacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002580             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18088:15456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002580
VERSION     KCVT01002580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18088:15456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..384
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80105.1"
                     /translation="CQQGYRYPYSF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           99 t
ORIGIN      
        1 acatgggggt gcaggagtca gtctcagtca ggacacagca tggacatgag ggtccccgct
       61 cagctccttg ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg
      121 cagtctccat cctccctgtc cgcatctgtg ggagacacag tcacgatcac ttgccaggcg
      181 agtcaaggca ttgacattaa tttaaattac tatcaacaga aaccagggaa agcccctaaa
      241 ctcctgatct atagggcatc ccgtttgcaa agtgggattc cctctcggtt cagcggcagt
      301 ggatctggga cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact
      361 tattactgtc aacagggtta tcgttacccg tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01002581             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24919:9556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002581
VERSION     KCVT01002581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24919:9556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80106.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01002582             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15812:11255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002582
VERSION     KCVT01002582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15812:11255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80107.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag caaaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002583             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7563:3595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002583
VERSION     KCVT01002583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7563:3595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80108.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac tcgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01002584             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:4813:13002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002584
VERSION     KCVT01002584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4813:13002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80109.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          116 c          104 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaatc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt attactgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002585             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12640:3028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002585
VERSION     KCVT01002585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12640:3028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80110.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          124 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002586             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:27269:14895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002586
VERSION     KCVT01002586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:27269:14895"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80111.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          125 c          112 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaaatgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002587             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8605:11605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002587
VERSION     KCVT01002587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8605:11605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80112.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cattctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002588             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11621:17985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002588
VERSION     KCVT01002588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11621:17985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80113.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002589             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11004:8700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002589
VERSION     KCVT01002589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11004:8700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..414
                     /note="immunoglobulin light chain variable region"
     V_region        98..414
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80114.1"
                     /translation="CQQGHSYPWTF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>422
                     /gene="IGKC"
BASE COUNT          101 a          114 c          113 g           94 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcacgatc acttgccagg cgagtgaagg
      181 cattggcaat aattcaaatt ggtatcagca gaaagcaggg aaagccccta aactcctgat
      241 ctatagggca tccagtttgc aaagtgggat tccctctcgg ttcagcggcc gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt catagttacc cgtggacgtt cggccaaggg tccaaggtgg aaataaaagg
      421 ag
//
LOCUS       KCVT01002590             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12955:19244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002590
VERSION     KCVT01002590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12955:19244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80115.1"
                     /translation="CQQYNSSPFTF"
     J_segment       390..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          110 a          115 c          109 g           96 t
ORIGIN      
        1 acatgggggg gcaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctag gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc
      121 gagtctccat cctccctgtc tgcatctgta ggagacagag taaccatcac ttgtcgggcg
      181 agtcaggaca taagaagtta tttagcgtgg tatcagcaga aaccaggcaa agccccgaag
      241 cccttgatct attacggatc cgttttggaa agtggggtcc catcaaggtt cagtggcagt
      301 ggatctggga cagatttcac tctcaccatc agcagtctgc agcctgaaga ttttgcaact
      361 tattactgtc aacagtataa cagtagccca ttcactttcg gccccgggac caaactggat
      421 atcaaacgag
//
LOCUS       KCVT01002591             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18524:9871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002591
VERSION     KCVT01002591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18524:9871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80116.1"
                     /translation="CQQRYRFPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           92 a          114 c          111 g          102 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagttgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcca gtcagggcat
      181 tagcaattat ttagcctggt atcagcagaa agtagggaaa gcccctaacc tcctgatcta
      241 taaggcgtcc agtttgcaga ctggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcagttt attactgtca
      361 acagcgttat cgtttcccgc tcactttcgg tggagggacc agggtggaga tcaaacgag
//
LOCUS       KCVT01002592             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22362:13214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002592
VERSION     KCVT01002592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22362:13214"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80117.1"
                     /translation="CQQDFGWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          120 c          117 g           89 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagactgttg gcagcgcctt agcctggtac cagcagaaac ctgggcagac tcacaaactc
      241 ctcatttatg gtgcatccag cagggccacc ggcatcccag acaggttcag tggcagtggg
      301 tctggaacag agttcactct caccatcagt agtccggagc ctgaggacgt tggactttat
      361 tattgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01002593             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:4636:17997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002593
VERSION     KCVT01002593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:4636:17997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80118.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002594             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12760:2848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002594
VERSION     KCVT01002594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12760:2848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80119.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c          102 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01002595             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11238:10484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002595
VERSION     KCVT01002595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11238:10484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80120.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gccccttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002596             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21491:9000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002596
VERSION     KCVT01002596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21491:9000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80121.1"
                     /translation="CMQAREFPFTF"
     J_segment       265..302
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           75 a           77 c           86 g           67 t
ORIGIN      
        1 acatggggga gagccggcct ccatctcctg caggtctagt cagagcctct tcgatagtga
       61 ggaggggaac acctatttgg aatggtacct acagaagcca ggccagtctc cacaactctt
      121 gatttatgag gtctccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      181 agacactgat ttcacactga aaatcagcag agtggaggct gaggatgctg gggtttatta
      241 ctgcatgcaa gctcgagagt ttccattcac tttcggcccc gggaccaaac tggacatcaa
      301 acgag
//
LOCUS       KCVT01002597             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11693:20552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002597
VERSION     KCVT01002597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11693:20552"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80122.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcagt cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002598             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17886:14075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002598
VERSION     KCVT01002598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17886:14075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80123.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actgtccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002599             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10929:20045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002599
VERSION     KCVT01002599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10929:20045"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80124.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002600             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10540:4035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002600
VERSION     KCVT01002600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10540:4035"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80125.1"
                     /translation="CQQNSNRPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g           87 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aattgtgatg acgcagtctc
      121 cagccaccct gtctttgtca ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag tagtttagcc tggtaccagc agagacctgg cagcctccca ggctcctcat
      241 ctatggtgcg tccagcaggg ccactggcat cccagacaga ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcccgaa gatgttgcag tttatttttg
      361 tcagcagaat agtaatcggc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002601             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12228:7356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002601
VERSION     KCVT01002601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12228:7356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80126.1"
                     /translation="CLQYKTYPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          112 c          109 g          100 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg cttctgtagg agacactgtc accatcactt gccgggcaag
      181 tcagggtatt gctggttatt taaattggtt tcagaagaaa ccagggaaag cccctaagct
      241 cctgatccaa gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtataaaa cttatccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01002602             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10558:11891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002602
VERSION     KCVT01002602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10558:11891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80127.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          123 c          116 g           85 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01002603             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24478:5751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002603
VERSION     KCVT01002603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24478:5751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80128.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002604             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:26088:10534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002604
VERSION     KCVT01002604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26088:10534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80129.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca gccttggaga gccggcctcc attttctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002605             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:22647:10197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002605
VERSION     KCVT01002605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22647:10197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..379
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80130.1"
                     /translation="CQQGYSYPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          119 c          110 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgcaggaga cacagtcacc atcacttgcc aggcgagtca
      181 aggcattggc aatactttaa attggtatca acagaaaccg gggaaagccc ctacactcct
      241 gatctatagg gcatccggtt tgcaaagtgg gactccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcagcag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatagtt atccgtacag ttttggccag gggaccaaac tggagatcaa
      421 acgag
//
LOCUS       KCVT01002606             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21215:12821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002606
VERSION     KCVT01002606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21215:12821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80131.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcaactta gcctggtacc agcagagacc tgggcagtct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002607             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17129:3195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002607
VERSION     KCVT01002607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17129:3195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..294
                     /note="immunoglobulin light chain variable region"
     V_region        6..294
     V_segment       6..256
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80132.1"
                     /translation="CLQSKNSPWSF"
     J_segment       257..294
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>297
                     /gene="IGKC"
BASE COUNT           83 a           74 c           78 g           62 t
ORIGIN      
        1 acatggggca gagggccacc atcacctgca gagccagtga gagtgtcagt gcctttggaa
       61 taagcctcat tcactggtat caacagaaac caggacaacc tcctaaactc ctgatttacc
      121 aagcaatcaa taaggagact ggggtcccag ccaggttcag cggcagtggg tctgggaccg
      181 atttcaccct cacaattaat cctgtggaac ctgacgatgg tgcagattat tactgtctgc
      241 agagtaagaa ttctccgtgg tcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01002608             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8564:14855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002608
VERSION     KCVT01002608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8564:14855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80133.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002609             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22703:6658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002609
VERSION     KCVT01002609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22703:6658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..424
                     /note="immunoglobulin light chain variable region"
     V_region        118..424
     V_segment       118..387
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80134.1"
                     /translation="CMQAREFPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           94 a          110 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagaccc
      121 gtcactcttg gagagccggc ctccatctcc tgcatgtcta gtcagagcct cttggatagt
      181 gaggatggaa acacctatgt ggaatggtac ctgcagaagc caggccagtc tccacagctc
      241 ttgatttatg aggtttccta ccgggcctct ggagtcccag acaggttcag tggcagtggg
      301 tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat
      361 tactgcatgc aagctcgaga gtttcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01002610             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:24499:9651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002610
VERSION     KCVT01002610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24499:9651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80135.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatgcagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aagtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 atgatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002611             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19172:13773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002611
VERSION     KCVT01002611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19172:13773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80136.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002612             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21182:18054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002612
VERSION     KCVT01002612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21182:18054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80137.1"
                     /translation="CQQHDNAPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          109 a          117 c          117 g           85 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcagagtatt aacgactggt tggcctggta tcaacagaga ccagggaagg cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcagcatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcag cagcatgaca atgccccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01002613             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22823:14955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002613
VERSION     KCVT01002613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22823:14955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..363
                     /note="immunoglobulin light chain variable region"
     V_region        86..363
     V_segment       86..325
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80138.1"
                     /translation="CQQYDSFPFTF"
     J_segment       326..363
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT           98 a           98 c           88 g           82 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggag acagagtcac catcacttgc cgggcaagtc
      121 aggacattag cagttattta aactggtatc agcagaaacc ggggaaagcc cctaaactcc
      181 tgatctatta tacaaatcgt ttggaaactg gggtcccatc aaggttcagc ggcagtggat
      241 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      301 actgtcaaca gtatgatagt tttccattca ctttcggccc cgggaccaaa ctggatatca
      361 aacgag
//
LOCUS       KCVT01002614             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18452:13865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002614
VERSION     KCVT01002614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18452:13865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80139.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          117 c          111 g           87 t
ORIGIN      
        1 acatgggggg gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 aggatattaa cacctggttg gcctggtatc aacagaagcc agggaaagcc cctaaggtcc
      241 tgatctatag gacatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcaaca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002615             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11553:2985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002615
VERSION     KCVT01002615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11553:2985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..435
                     /note="immunoglobulin light chain variable region"
     V_region        115..435
     V_segment       115..397
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80140.1"
                     /translation="CQQYNDFLLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          125 c          119 g           93 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggatccc agataccgcc ggaaaaattg
      121 ttatgacgca gtctccagcc accctgtctt tgtctccagg ggaaacagcc accctctcct
      181 gcagggccag tgagaatgtt ggcaactact tagcctggta ccagcagaaa cctgggcagg
      241 ctcccaggct ccttgtccat agtgcatcct tcagggccac tggcatccca gacaggttca
      301 gtggcagcgg gtctaggaca gagttcactc tcaccattag cagcctggag cctgaagatg
      361 ttggacttta tcactgtcag caatataatg acttcctgct cactttcggc ggagggacca
      421 aggtggaggt caaacgag
//
LOCUS       KCVT01002616             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9360:22312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002616
VERSION     KCVT01002616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9360:22312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80141.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgtgc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002617             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15658:17594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002617
VERSION     KCVT01002617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15658:17594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80142.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          112 c          105 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 cgtcctccct gtctgcttct gtgggagaca gagtcaccat cagttgccgg gcaagtcagg
      181 acattatcag ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tcttttatac aaaccgtttg gaaactgggg tcccaccaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tacaacctga agaatttgga acttattact
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002618             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20765:11388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002618
VERSION     KCVT01002618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20765:11388"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80143.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002619             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14381:17366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002619
VERSION     KCVT01002619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14381:17366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80144.1"
                     /translation="CLQYKSYPFTF"
     J_segment       379..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          105 a          112 c          101 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc caactgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagtagttat ttaaattggt ttcagcagaa aacagggaag gcccctaagc tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatttgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccat tcactttcgg ccccgggacc aaactggaca tcaaaggag
//
LOCUS       KCVT01002620             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7039:11776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002620
VERSION     KCVT01002620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7039:11776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80145.1"
                     /translation="CQQHDNSPPTF"
     J_segment       243..277
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           78 a           68 c           72 g           62 t
ORIGIN      
        1 acatggggag tcaccatcac ttgcagagcc agtcagggta ttagcgactg gttggcctgg
       61 tatcaacaga aaccagggaa agcccctaaa ctcctgatct atagggcatc caatttggaa
      121 acaggggtcc catcaaggtt cagtggaagt ggatctggga cagatttcac tctcaccatc
      181 agcagcctgc aggctgaaga tttcgcaaca tatttctgtc aacagcatga taattcccct
      241 cccactttcg gtggagggac taaggtggag atcaaacgag
//
LOCUS       KCVT01002621             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19414:7762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002621
VERSION     KCVT01002621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19414:7762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80146.1"
                     /translation="CMQVLEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           92 a          123 c          121 g          108 t
ORIGIN      
        1 acatgggggc tgctcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg catccggtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgacg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ttctagagtt tcctctcact ttcggtggag
      421 ggaccacggt ggagatcaaa cgag
//
LOCUS       KCVT01002622             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18551:8874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002622
VERSION     KCVT01002622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18551:8874"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80147.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          119 c          123 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac gtagtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagtc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgggga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002623             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20404:6173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002623
VERSION     KCVT01002623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20404:6173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80148.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagtctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat cccctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aggccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002624             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12150:10424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002624
VERSION     KCVT01002624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12150:10424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..402
                     /note="immunoglobulin light chain variable region"
     V_region        81..402
     V_segment       81..364
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80149.1"
                     /translation="CQQYNSLPLTF"
     J_segment       365..402
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>405
                     /gene="IGKC"
BASE COUNT          104 a          103 c          102 g           96 t
ORIGIN      
        1 acatgggaca cagcatggac atgagggtcc ccgctcagct cctggggctc ctgctgctct
       61 ggctcccagg tgccagatgt gacattcaga tgacccagtc tccatcctcc ctgtctgcat
      121 ctgtaggaga cagagtcacc atcacttgcc gggcaagtca ggacattagc agatatttaa
      181 attggtatca gcagaaaccg gggaaagccc ctaagttcct gatctattat gtaaaccgtt
      241 tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca
      301 ccatcagcag cctgcaacct gaagattttg caacttatta ttgtcaacag tataatagtt
      361 taccgctcac tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002625             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18146:10687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002625
VERSION     KCVT01002625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18146:10687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80150.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggtctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002626             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7890:9767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002626
VERSION     KCVT01002626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7890:9767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80151.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          123 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttggtt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaagctgga aatcaaacga g
//
LOCUS       KCVT01002627             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19001:19528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002627
VERSION     KCVT01002627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19001:19528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80152.1"
                     /translation="CLHYNSDPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          108 c          107 g          102 t
ORIGIN      
        1 acatggggga gttagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc tgtaagagac agagtcacct tcacttgcag ggcaagtcag
      181 ggcattacaa cttttttaaa ttggtgtcag cagaaatcag gaaaaactcc taagcgcctg
      241 atctgtgttg aatacagttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacaggtt tcactctcac catcagcagc ctgcagcctg aagattttac aacttattcc
      361 tgtcttcatt ataacagtga cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002628             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12203:15048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002628
VERSION     KCVT01002628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12203:15048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80153.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaga
      421 cgag
//
LOCUS       KCVT01002629             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18303:6411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002629
VERSION     KCVT01002629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18303:6411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80154.1"
                     /translation="CMQGTHLPYSF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          117 c          115 g           99 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg gtccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca accggcctcc atttcctgca ggtctagtca tagccttgta
      181 cacagtgatg ggaataccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggactt
      361 tattactgca tgcaaggtac acaccttccg tacagttttg gccaggggac cgaaatagag
      421 atcaaacgag
//
LOCUS       KCVT01002630             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17046:18151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002630
VERSION     KCVT01002630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17046:18151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..376
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80155.1"
                     /translation="CQQYYSFPITF"
     J_segment       390..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>428
                     /gene="IGKC"
BASE COUNT          101 a          114 c          115 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggatccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtggg agacaaagtc accatcactt gccgagccag
      181 tcagggtatt aacacctggt taatttggta tcagcagaaa ccagggaaag cccctaaggc
      241 cctgatctat aaggcatcca gtttgcaagg tggggtccct tccaggttca gcggcagtgg
      301 atctggggca gacttcactc tcaccatcac caacctgcag cctgaagatt ttggaattta
      361 ttactgtcaa caatattata gttttccgat cactttcggt ggggggacca aggtggagat
      421 caggcgag
//
LOCUS       KCVT01002631             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8339:19907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002631
VERSION     KCVT01002631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8339:19907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80156.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          117 c          107 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggattgg
      301 gacagatttc actctcagca tcagcagcct gcagcctgaa gatttcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002632             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20799:14236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002632
VERSION     KCVT01002632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20799:14236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80157.1"
                     /translation="CQQHDNSPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          115 c          110 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagagtat
      181 taacgactgg ttggcctggt atcaacagag accagggaag gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat aattccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002633             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15961:11973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002633
VERSION     KCVT01002633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15961:11973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80158.1"
                     /translation="CLQGYSPPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          118 c          110 g           98 t
ORIGIN      
        1 acctggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgattattta ggttggtatc agcagaaacc aggaaaaact cctgagcgcc
      241 tgatctatgc tgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaggttatt
      361 tctgtctgca gggttatagt cccccattca ctttcggccc cgggaccaaa ctggatttca
      421 aacgag
//
LOCUS       KCVT01002634             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13023:12199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002634
VERSION     KCVT01002634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13023:12199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80159.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002635             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18193:21141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002635
VERSION     KCVT01002635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18193:21141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..366
                     /note="immunoglobulin light chain variable region"
     V_region        89..366
     V_segment       89..324
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80160.1"
                     /translation="CQQYDSDSLTF"
     J_segment       329..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           93 a           97 c          100 g           79 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gagacagagt caccatcact tgtcgggcga
      121 ctcaggacat tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc
      181 ccttgatcta ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      301 attactgtca acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01002636             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:25590:16533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002636
VERSION     KCVT01002636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25590:16533"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80161.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggc tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002637             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:4753:14392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002637
VERSION     KCVT01002637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4753:14392"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80162.1"
                     /translation="CQQYNTLPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          117 c          103 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgag attcagatga cccagtctcc
      121 atcctccctg tctgcctctg tcggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaat tatttaaatt ggtatcagca gagaccgggg aaagccccta aactcctgat
      241 ctattatgca tcccgtttgg agaatggggt cccatcaaag ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagtagcct gcaacctgaa gattttgcag cttattactg
      361 tcagcagtat aataccttac cattcacttt cggccccggg accaaactgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002638             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21172:16269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002638
VERSION     KCVT01002638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21172:16269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..409
                     /note="immunoglobulin light chain variable region"
     V_region        96..409
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80163.1"
                     /translation="CQQGHSYPWTF"
     J_segment       380..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>420
                     /gene="IGKC"
BASE COUNT           98 a          116 c          111 g           95 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccagtcg agtctaggca
      181 ttggcaaatt tttaaattgg tatcagcaga aaccagggaa agcccccaaa ctcctgatct
      241 atagggcatc cagtttgcaa actgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccgct tattactgtc
      361 aacagggtca tagttacccg tggacgttcg gccaagggac caaggtggag atgaaacgag
//
LOCUS       KCVT01002639             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10919:6455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002639
VERSION     KCVT01002639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10919:6455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80164.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          112 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagctgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttacaactt atttctgtca
      361 acagtataac agtgacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002640             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19196:17593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002640
VERSION     KCVT01002640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19196:17593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80165.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002641             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17027:8707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002641
VERSION     KCVT01002641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17027:8707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80166.1"
                     /translation="CQQYNSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002642             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14451:3581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002642
VERSION     KCVT01002642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14451:3581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80167.1"
                     /translation="CMQGLEFPITF"
     J_segment       404..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atactgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgatgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cgctgatttc acactgagaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc caatcacttt cggccccggg
      421 accaaactgg agatcaaacg ag
//
LOCUS       KCVT01002643             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21950:14525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002643
VERSION     KCVT01002643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21950:14525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80168.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacat atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002644             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5678:16943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002644
VERSION     KCVT01002644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5678:16943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..400
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80169.1"
                     /translation="YMQSTKDPLTF"
     J_segment       402..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          123 c          110 g          107 t
ORIGIN      
        1 acatgggggt gatcaggact cctcagttca tcttctcacg atgagactcc ctgctcagct
       61 cctcgggctg ttgatgctct gggtccctgg atccagtggc gatattttgc tgacccagac
      121 tccactctcg ctgcccgtca tccctggaga gccggcctcc atctcctgca ggtctagtca
      181 aagccttctg catagtaatg gatacaccta tttgcattgg tacctgcaga agccaggcca
      241 gtctccacgg ctcctgatct ataaagttac caatcgggaa tctggggtcc cagacaggtt
      301 cagcggcagt gggtcaggca tagatttcac actgaaaatc agcagggtgg agcctgagga
      361 tgttggtgtt tattactaca tgcaaagtac aaaagatccc ctcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01002645             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11172:20839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002645
VERSION     KCVT01002645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11172:20839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80170.1"
                     /translation="CQQGYTYLYSF"
     J_segment       379..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          117 c          102 g           98 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgtt ggagacacag tcaccatcac ttgccaggcg agtcaagcca
      181 ttgccaataa tttaaattgg tatcagcaga aaccaggaaa agcccctaaa gtcctaatct
      241 ataaggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcgccctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tacttacctg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01002646             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18867:13339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002646
VERSION     KCVT01002646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18867:13339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80171.1"
                     /translation="CQQYNSDPFTF"
     J_segment       364..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          103 a          111 c           98 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctaggactcc tgctgctctg
       61 tctcccaggt gccaaatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtaacca tcacttgtcg ggcgagtcag gacataagaa gttatttagc
      181 gtggtatcag cagaaaccag gcaaagcccc gaagcccttg atctattacg catccgtttt
      241 ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct gggacagaat tcactctcac
      301 catcagcagt ctgcagcctg aggattttgc aacttattac tgtcaacagt ataacagtga
      361 cccattcact ttcggccccg ggaccaaact ggataccaaa cgag
//
LOCUS       KCVT01002647             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:23351:8818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002647
VERSION     KCVT01002647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23351:8818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..432
                     /note="immunoglobulin light chain variable region"
     V_region        95..432
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80172.1"
                     /translation="CMQSLDFPLTF"
     J_segment       397..432
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>437
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gttatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacacag atttcacact gaaaatcagc agagtggaga ctgaggatgt
      361 tggggtttat tactgcatgc agtctctaga ttttccgctc actttcggtg gagggaccaa
      421 ggtggagatc aatcgag
//
LOCUS       KCVT01002648             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:25702:9965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002648
VERSION     KCVT01002648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25702:9965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80173.1"
                     /translation="CQQYNSDPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          117 c          110 g           90 t
ORIGIN      
        1 atgggggcag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 aggacattac cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatgtatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gaccctccga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002649             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16932:15666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002649
VERSION     KCVT01002649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16932:15666"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80174.1"
                     /translation="CQQHADSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          110 a          121 c          109 g           88 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      181 ccacgatata aataattggt tggcctggta tcaacagaaa ccaggaaaag cccctaacct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt tcgcaacata
      361 ttactgtcaa cagcatgctg attcccctcg gacgttcggc caagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002650             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17882:5649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002650
VERSION     KCVT01002650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17882:5649"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80175.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002651             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10685:10176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002651
VERSION     KCVT01002651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10685:10176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80176.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          121 c          119 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag gtactaccgg agaaatagtg gtgacacagt
      121 ctccagacac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaacct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga attcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002652             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7121:22341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002652
VERSION     KCVT01002652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7121:22341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80177.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgagacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002653             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19250:12817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002653
VERSION     KCVT01002653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19250:12817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80178.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002654             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9303:20204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002654
VERSION     KCVT01002654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9303:20204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80179.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggaggtcaa
      421 acgag
//
LOCUS       KCVT01002655             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17214:6735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002655
VERSION     KCVT01002655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17214:6735"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80180.1"
                     /translation="CLQGYITPYSF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          112 c          113 g          100 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tccttctgct ctggctccca ggtgccagat gtgacttcca gatgacccag
      121 tctccatctt ccctgtctgc atcggtagga gacagagtca ccatcacttg ccgggcaagt
      181 caggacatta gcgatttttt aagttggtat cagcagaaac caggaaaacc tcctaagcgc
      241 ctgatttatg ctgcatccag tttgcaaagt ggggtcccgt caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcggcttat
      361 tattgtctac agggttatat taccccgtac agttttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01002656             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19455:10645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002656
VERSION     KCVT01002656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19455:10645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80181.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt cagcatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttggcgtggt atcaccagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01002657             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13899:17079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002657
VERSION     KCVT01002657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13899:17079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80182.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 ttggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002658             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:25608:13556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002658
VERSION     KCVT01002658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25608:13556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80183.1"
                     /translation="CQQYNSEPRTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           90 t
ORIGIN      
        1 acatggggca gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa acccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgagccg cgcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01002659             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9331:17100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002659
VERSION     KCVT01002659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9331:17100"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80184.1"
                     /translation="CQQYSSLVAF"
     J_segment       385..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          106 c          111 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccca aaggtcctga
      241 tctattctgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc attagcaacc tacaacctga ggattttgca acttattact
      361 gtcaacagta tagtagttta gtcgctttcg gtggagggat caaggtggag atcaaacgag
//
LOCUS       KCVT01002660             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:3636:9759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002660
VERSION     KCVT01002660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:3636:9759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80185.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgacg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002661             385 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20215:12688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002661
VERSION     KCVT01002661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 385)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20215:12688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..382
                     /note="immunoglobulin light chain variable region"
     V_region        43..382
     V_segment       43..344
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <322..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80186.1"
                     /translation="CMQALDFPWTF"
     J_segment       345..382
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>385
                     /gene="IGKC"
BASE COUNT           88 a           98 c          108 g           91 t
ORIGIN      
        1 atggggggac tgctaatgct ctggctccct ggatccattg gggacattgt gatgacccag
       61 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      121 cagagcctct tggatagtga ggatggaaac acctatttgg aatggttcct gcagaagcca
      181 ggccagtctc cacaactctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      241 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      301 gaggatgttg ggatttatta ctgcatgcaa gctctagact ttccgtggac gttcggccaa
      361 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002662             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11698:11301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002662
VERSION     KCVT01002662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11698:11301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80187.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcatc cttggagagc cggcctccct atcctgcacg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cacttaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002663             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21659:11318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002663
VERSION     KCVT01002663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21659:11318"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80188.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcacctta acctggtacc accagaagcc tgggcaggct cccaagctcc
      241 tcatctatgg tccatccatc agggccagcg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga atttactctc accatcagca gcctggagac tgaagatgtt ggagtttatt
      361 actgtcagca ggattatcac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002664             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18862:16411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002664
VERSION     KCVT01002664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18862:16411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    31..352
                     /note="immunoglobulin light chain variable region"
     V_region        31..352
     V_segment       31..310
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <292..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80189.1"
                     /translation="CQQYDSDSLTF"
     J_segment       315..352
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>355
                     /gene="IGKC"
BASE COUNT           91 a           92 c           91 g           81 t
ORIGIN      
        1 acatgggggc caatctcagg tgccaaatgt gacatccaga tgacccagtc tccatcctcc
       61 ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca ggacattcgc
      121 agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt gatctattac
      181 gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa
      241 ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta ctgtcaacag
      301 tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002665             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14438:16696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002665
VERSION     KCVT01002665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14438:16696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80190.1"
                     /translation="CMQPLEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          123 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctc cagaagccag
      241 gccagtctcc acatctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg ttcggccagg
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002666             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9928:11319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002666
VERSION     KCVT01002666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9928:11319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80191.1"
                     /translation="CQHSFRTPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          116 c          109 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaatgt cacttgcagg gctagtgaga
      181 gcgttagcac caaattacat tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc gtccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gaacagattt cactctcacc atcagcagcc tgcagcctga agatgtcgca actttttact
      361 gtcagcatag ttttcgtacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002667             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8667:7484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002667
VERSION     KCVT01002667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8667:7484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..382
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80192.1"
                     /translation="CYQHSRGWAF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           97 a          123 c          117 g           84 t
ORIGIN      
        1 acatgggggc tgctgctagg ttagtaccca gaaggaacca tggaagcccc agctcagctt
       61 ctctgccttc tgctactctg gctcccaggt accaccggac aaattatatt gacacagtct
      121 ccagccaccc tgtctttggc accaggggaa agagccactc tctcctgcag ggccagtgag
      181 aatgttggca gctacttagc ctggtaccag cagaaccctg ggcaggctcc caggctcctc
      241 gtccacagtg cgtccagcag ggccactgac atcccagaca ggttcagtgg cagtgggtct
      301 cggacagagt tcaccctcac catcagcagt ctggagcctg aagatgttgg agtctattac
      361 tgctatcaac atagcagggg gtgggcgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01002668             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14250:24864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002668
VERSION     KCVT01002668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14250:24864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80193.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccggga ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002669             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17289:15596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002669
VERSION     KCVT01002669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17289:15596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..413
                     /note="immunoglobulin light chain variable region"
     V_region        96..413
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80194.1"
                     /translation="CQQYDSDPYSF"
     J_segment       380..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>420
                     /gene="IGKC"
BASE COUNT          104 a          112 c          112 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttaggagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag gccttgatct
      241 attacacatc cattttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgagga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg tacagttttg gccaggggac cagagtggag atccaacgag
//
LOCUS       KCVT01002670             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7515:11638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002670
VERSION     KCVT01002670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7515:11638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..287
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80195.1"
                     /translation="CQQNSNWPLTF"
     J_segment       288..324
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>327
                     /gene="IGKC"
BASE COUNT           78 a           92 c           89 g           68 t
ORIGIN      
        1 acatgggagt gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca
       61 ccctctcctg cagggccagt cagagtgtca gcagcagctt agcctggtac caacaaaaac
      121 ctgggcaggc tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag
      181 acaggttcag tggcagtggg tctgggacag acttcactct caccatcacc agcctggagc
      241 ctgaagatgt tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg
      301 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01002671             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8861:9563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002671
VERSION     KCVT01002671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8861:9563"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80196.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          119 c          110 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      181 ccacgatata aataactggt tggcctggta tcaacagaaa ccaggaaaag cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcagcatcag cagcctgcag cctgaagatt tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01002672             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16946:6507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002672
VERSION     KCVT01002672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16946:6507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80197.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002673             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21265:17846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002673
VERSION     KCVT01002673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21265:17846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80198.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcaacagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002674             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13991:19739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002674
VERSION     KCVT01002674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13991:19739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80199.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcacccc tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggattggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctctg gagtttcctt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002675             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11097:17168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002675
VERSION     KCVT01002675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11097:17168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80200.1"
                     /translation="CLQYNSGPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          111 c          107 g           99 t
ORIGIN      
        1 acatggggga agttagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat ctgaaggaga cagagtcacc atctcttgca gggcaagtca
      181 ggccattagt atttatttaa attgcaatca acagaaacca ggaaaagctc ctcagcgcct
      241 gatctatgct gcatccagtt tggaaagtgg ggtcccatta aggttcagtg gcagtggatc
      301 tgggacagat ttcactctca ccatcagtag cctacagcct gaagattttg caacttattc
      361 ctgtctacag tataacagtg gcccgtggac gttcggccga gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002676             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15441:5268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002676
VERSION     KCVT01002676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15441:5268"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80201.1"
                     /translation="CQQYDSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcttgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattag cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctattt cgcatccact ttggaaagtg gcgtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002677             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11323:18153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002677
VERSION     KCVT01002677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11323:18153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80202.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggatattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002678             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10216:13417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002678
VERSION     KCVT01002678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10216:13417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80203.1"
                     /translation="CMQPREFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tcttgtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggccgagg
      361 atgttggggt ttattactgc atgcaacctc gagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga catcaaacga g
//
LOCUS       KCVT01002679             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14087:11362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002679
VERSION     KCVT01002679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14087:11362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80204.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          101 a          110 c          108 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagag accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01002680             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18900:15292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002680
VERSION     KCVT01002680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18900:15292"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..415
                     /note="immunoglobulin light chain variable region"
     V_region        102..415
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80205.1"
                     /translation="CLQGDSTPFTF"
     J_segment       392..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>426
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           95 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgattattta agttggtatc agcagaaacc gggaaaagct cctaagcgcc
      241 taatctatgc tgcatccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc accatcagca gcctgcagcc tgaagatttt gcgacttatt
      361 actgtctaca gggtgatagt accccgttca cttttggcca ggggaccaaa gtggacgtca
      421 aacgag
//
LOCUS       KCVT01002681             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6064:17406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002681
VERSION     KCVT01002681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6064:17406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80206.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaagat ggaaacacct atttggagtg gtatctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002682             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11007:19707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002682
VERSION     KCVT01002682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11007:19707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80207.1"
                     /translation="CQQHDNSPPTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          117 c          111 g           94 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccttcc tccctgtctg catctgtagg cgacagagtc accatcactt gcagagccag
      181 tcagggtatt agcgactggt tggcctggta tcaacagaaa ccagggaaag cccctaaact
      241 cctgatctat agggcttcca atttggaaac aggggtccca tcaagattca gtggaagtgg
      301 atctggaaca gatttcactc tcaccatcag cagcctgcag gctgaagatt tcgcaacata
      361 tttctgtcaa cagcatgata attcccctcc cactttcggt ggagggacta aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002683             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20811:14796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002683
VERSION     KCVT01002683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20811:14796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80208.1"
                     /translation="CLQYKSFPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          113 c          101 g          101 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtggc atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg tgggagacac tgtcaccatc acttgccgga caagtcaagg
      181 tattaccaat tatttacatt ggtttcagca gaaaccaggg aaagccccta agctcctgat
      241 ctatgaaaca tccagtttgg taagtggggt cccatcaagg ttcagcggca gtgcatctgg
      301 gacagaattc actctcacca tcagcagcct acagcctgaa gattttgcat cttattactg
      361 tctacagtat aaaagtttcc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002684             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10079:8355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002684
VERSION     KCVT01002684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10079:8355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80209.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgtt gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002685             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5429:16005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002685
VERSION     KCVT01002685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5429:16005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80210.1"
                     /translation="CQQYDSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          112 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002686             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17170:18330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002686
VERSION     KCVT01002686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17170:18330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80211.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tacatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002687             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:25477:16495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002687
VERSION     KCVT01002687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25477:16495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80212.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          124 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttc cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaagcg ggcctctgga gtcgcagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002688             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14459:11387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002688
VERSION     KCVT01002688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14459:11387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..399
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80213.1"
                     /translation="CMQALQTPYSF"
     J_segment       400..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          116 c          120 g          108 t
ORIGIN      
        1 acatgggggt gatcaggact cctcagttca ccttgtcaca atgaggctcc ctgctcagct
       61 cctggggctg ctaatgctct gggtctctgt ctccagtgga gatatcgtga tgacccagac
      121 tccactctcg ctgcccgtca cccttggaga gccagcctcc atctcctgca ggtctagtca
      181 gagccttctg aatagtaatg gatacaacta tttgaattgg tacctgcaga agccaggcca
      241 gtctccacat cttctgatct attatggttc tagtcgggcc tccggggtcc ccgacaggtt
      301 cagtggcagt gggtcaggca cagattttac actgaaaatc agcagggtgg aggctgggga
      361 cgtaggggtt tattactgca tgcaagctct acaaactccg tacagttttg gccaggggac
      421 cagagtggag atcaaacgag
//
LOCUS       KCVT01002689             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4893:9741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002689
VERSION     KCVT01002689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4893:9741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80214.1"
                     /translation="CQQYNSLPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          100 a          103 c          104 g           97 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattgagat gacccagtct ccatcctccc tgtctgcttc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag ggcgttaacg tttatttaaa
      181 ttggtatcaa cagaaaccgg ggaaagcccc taagcccctg atcttttatg caaaccgttt
      241 ggaacgtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaacctg aagattttgc aagttattat tgtcaacagt ataatagttt
      361 accgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01002690             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16364:11056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002690
VERSION     KCVT01002690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16364:11056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80215.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          127 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cactctccct gtccgtcacc ctcggagagt cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002691             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22915:4878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002691
VERSION     KCVT01002691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22915:4878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80216.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagc caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002692             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7139:7445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002692
VERSION     KCVT01002692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7139:7445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..399
                     /note="immunoglobulin light chain variable region"
     V_region        78..399
     V_segment       78..352
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80217.1"
                     /translation="CQQHNNYSPTF"
     J_segment       365..399
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>402
                     /gene="IGKC"
BASE COUNT           99 a          113 c          101 g           89 t
ORIGIN      
        1 acatggggag catggacatg agggtccccg ctcagctcct ggggctcctg ctgctctggc
       61 tcccaggtgc cagatgtgac atccagatga cccagtctcc accctccctg tctgcatctg
      121 taggagacac agtcaccatc acttgtcggg caagtcaggg cattagcaat gatttagcct
      181 ggtatcagct gaaaccaggg aaagccccga agcccctgat ctattacgca tccaatttgg
      241 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc actctcacca
      301 tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacaacat aataattact
      361 ctcccacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002693             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12348:12409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002693
VERSION     KCVT01002693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12348:12409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..409
                     /note="immunoglobulin light chain variable region"
     V_region        96..409
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80218.1"
                     /translation="CQQGHSYPWTF"
     J_segment       380..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>420
                     /gene="IGKC"
BASE COUNT           98 a          117 c          110 g           95 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccagtcg agtctaggca
      181 ttggcaaatt tttaaattgg tatcagcaga aaccagggaa agcccccaaa ctcctgatct
      241 atagggcatc cagtttgcaa actgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccgct tattactgtc
      361 aacagggtca tagttacccg tggacgttcg gccaagggac caaggtggag atgaaacgag
//
LOCUS       KCVT01002694             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15526:15685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002694
VERSION     KCVT01002694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15526:15685"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    48..361
                     /note="immunoglobulin light chain variable region"
     V_region        48..361
     V_segment       48..324
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <301..>333
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80219.1"
                     /translation="CMQALEFPPTF"
     J_segment       327..361
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        362..>364
                     /gene="IGKC"
BASE COUNT           86 a           94 c           98 g           86 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgcccgtc
       61 acccttggag agccggcctc catctcctgc aggtctagtc agagcctctt ggatagtggg
      121 gatggaaaca cctatttgga atggtaccta cagaagccag gccagtctcc acaactcttg
      181 atttatgagg tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca
      241 gacactgatt tcacactgaa aatcaacaga gtggaggctg aggatgttgg gttttattat
      301 tgcatgcaag ctctagagtt tcctcccact ttcggcggag ggaccaaggt ggagatcaaa
      361 cgag
//
LOCUS       KCVT01002695             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20974:18647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002695
VERSION     KCVT01002695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20974:18647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80220.1"
                     /translation="CQQGYSYPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          122 c          106 g           94 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc cgtaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattgaca ataatttaaa ttggtatcag caaaaaccag ggaaagcccc taaactcctg
      241 atctttgggg catccactct ccaaagtggg actccctcgc ggttcagcgg cagtgattct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttatttc
      361 tgtcaacagg gttatagtta ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002696             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12171:15344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002696
VERSION     KCVT01002696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12171:15344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..440
                     /note="immunoglobulin light chain variable region"
     V_region        119..440
     V_segment       119..403
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80221.1"
                     /translation="CQQNSNWPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          103 a          125 c          126 g           89 t
ORIGIN      
        1 acatgggggg ggtcagagct ctggggagga actgctcagt taggacccag agggaaccat
       61 ggaagcccca gcacagcttc tcttcctcct gctgctctgg ctcccagata ccaccggaga
      121 aatagtgatg acgcagtctc cagccaccct gtctttgtct ccaggagaaa gagccaccct
      181 ctcctgcagg gccagtcaga gtgtcagcag cagcttagcc tggtaccagc agaaacctgg
      241 gcaggctccc aggctcctca tctatggtgc atccaacagg gccactggca tcccagacag
      301 gttcagtggc agtgggtctg ggacagagtt cactctcacc atcagcagcc tggagcctga
      361 agatgttgca gtttattatt gtcagcagaa tagtaactgg cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002697             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11803:14630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002697
VERSION     KCVT01002697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11803:14630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80222.1"
                     /translation="CQQYDSDLLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga tttgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002698             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24798:13183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002698
VERSION     KCVT01002698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24798:13183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80223.1"
                     /translation="CQQYNSLPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          109 c          109 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctc tgggggacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaga tatttaaatt ggtatcagca gaaaccgggg aaagccccta agttcctgat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattattg
      361 tcaacagtat aatagtttac cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002699             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10438:9074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002699
VERSION     KCVT01002699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10438:9074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80224.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcagcagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002700             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11565:22842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002700
VERSION     KCVT01002700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11565:22842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80225.1"
                     /translation="CQQYNTLPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          116 c          102 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga gattcagatg acccagtctc
      121 catcctccct gtctgcctct gtcggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtaa ttatttaaat tggtatcagc agagaccggg gaaagcccct aaactcctga
      241 tctattatgc atcccgtttg gaaaatgggg tcccatcaaa gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagtagcc tgcaacctga agattttgca gcttattact
      361 gtcagcagta taatacctta ccattcactt tcggccccgg gaccaaactg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002701             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8702:14853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002701
VERSION     KCVT01002701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8702:14853"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80226.1"
                     /translation="CLQGYSPPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 ttacgattat ttaagttggt atcagcagac accaggaaaa actcctaagc gcctgatcta
      241 tgctgcatcc agtttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagggttat agtcccccgt ggacgttcgg ccaagggacc aaggtggaag tcaaacgag
//
LOCUS       KCVT01002702             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24781:7364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002702
VERSION     KCVT01002702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24781:7364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80227.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccatt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002703             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22254:14014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002703
VERSION     KCVT01002703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22254:14014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80228.1"
                     /translation="CQQDFDWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          127 c          112 g           88 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gagagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc tcccaagctc
      241 ctcctctttg gtacatccac cagggccacc ggcatcccag acaggttcag tgccagtggg
      301 tctcgaacag agtttactct caccatcagc agcctggagc ctgaagatgt tggaatttat
      361 tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01002704             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21577:10993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002704
VERSION     KCVT01002704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21577:10993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80229.1"
                     /translation="CQQYSTFPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          113 c          107 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtcg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacagttat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttttacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcagctt attactgtca
      361 gcagtatagt acttttcctc tcactttcgg cggagggacc aaggtggcga tcaaacgag
//
LOCUS       KCVT01002705             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4180:10617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002705
VERSION     KCVT01002705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4180:10617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80230.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          117 c          124 g          103 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tgatgctctg ggtccctggc tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002706             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8521:10085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002706
VERSION     KCVT01002706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8521:10085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80231.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          116 c          117 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcaacag aaaccaggac aacctcctaa
      241 actcctgatt taccaagcaa tcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat tagtcctgtg gaacctgacg atggtgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01002707             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:22057:3601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002707
VERSION     KCVT01002707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22057:3601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80232.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          120 c          116 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgacgatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002708             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24599:4330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002708
VERSION     KCVT01002708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24599:4330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80233.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          119 c          111 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tctcttgccg ggcgagtcag
      181 gacattcgca gttatttagc gtggtatcag cagagaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002709             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:10771:14590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002709
VERSION     KCVT01002709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10771:14590"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..416
                     /note="immunoglobulin light chain variable region"
     V_region        102..416
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80234.1"
                     /translation="CQQYNTLPLTF"
     J_segment       386..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>426
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacactcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattaa catttattta aattggtatc agcagaaacc ggggaaagcc cctgagctcc
      241 tgatctatta tgcaaaccgt ttggaaactg gggtcccatc aaggttcagc ggcggtggat
      301 ctgggacaga attcagtctc accatcagca gcctgcaacc tgaggacttt gcaacttatt
      361 actgtcaaca gtataatact ttaccgctca ctttcggcgg agggaccaag gtggaggtca
      421 gacgag
//
LOCUS       KCVT01002710             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22541:12484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002710
VERSION     KCVT01002710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22541:12484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80235.1"
                     /translation="CQQGHSYPWTF"
     J_segment       383..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT           99 a          118 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag tcgagtctag
      181 gcattggcaa atttttaaat tggtatcagc agaaaccagg gaaagccccc aaactcctga
      241 tctatagggc atccagtttg caaactggga ttccccctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc gcttattact
      361 gtcaacaggg tcatagttac ccgtggacgt tcggccaagg gaccaaggtg gagatgaaac
      421 gag
//
LOCUS       KCVT01002711             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:8004:17304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002711
VERSION     KCVT01002711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:8004:17304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..336
                     /note="immunoglobulin light chain variable region"
     V_region        9..336
     V_segment       9..292
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <270..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80236.1"
                     /translation="CQHRSGYPYMYTF"
     J_segment       298..336
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>339
                     /gene="IGKC"
BASE COUNT           88 a           86 c           84 g           81 t
ORIGIN      
        1 acatggggga cactcagttg acccagtctc catcctccct gtctgcatct gtaggagaca
       61 gagtcatcat cacttgtcgg acaagtcagg acattagcag ttatttagcc tggtatcagc
      121 agaaaccagg gaaagcccct aacctcctga tctataaggc gtccagtttg caaagtgggg
      181 tcccatcaag gttcagcggc agtggatctg ggacagattt cactctcacc atcagcagcc
      241 tgcaggctga agattttgca gtttattact gtcaacaccg tagtggttac ccgtacatgt
      301 acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002712             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12531:13628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002712
VERSION     KCVT01002712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12531:13628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80237.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc cccgacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002713             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9378:8722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002713
VERSION     KCVT01002713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9378:8722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80238.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           93 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cctattactg
      361 tcaacagtat gacagtgatc cgttcacttt cggtgggggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01002714             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20280:21681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002714
VERSION     KCVT01002714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20280:21681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..386
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80239.1"
                     /translation="CQQGYSFPFTF"
     J_segment       389..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           96 a          124 c          109 g           99 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctccttggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgacgca
      121 gtctccatcc tccctgtccg catctgtagg agacacagtc acgatcactt gccaggcgag
      181 tcaaggcatt ggcagtagtt taagctggta tcagcagaaa ccagggaaag cccctaacct
      241 cctgatcttt agggcatcca gtttgcaaag tgggattccc tctcggttca gcggcagtgg
      301 atctgggacg gatttcactc tcaccatcag cagcctccag cctgaagatt ttgccactta
      361 ttactgtcaa cagggttata gtttcccctt cactttcggc cccgggacca aactggatat
      421 caaacgag
//
LOCUS       KCVT01002715             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:6470:11677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002715
VERSION     KCVT01002715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6470:11677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80240.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttccaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcg cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002716             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17449:2795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002716
VERSION     KCVT01002716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17449:2795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80241.1"
                     /translation="CQQGYSYPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          120 c          105 g           98 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga tgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcacgatc acttgccagg cgagtcacgg
      181 cattggcaat aatttaaatt ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 ctatacggca tccaggttac aaggtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcggcct gcagcctgaa gatcttgcca cttattactg
      361 tcaacagggt tatagttacc cattcacttt cggtcccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01002717             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:9050:6205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002717
VERSION     KCVT01002717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9050:6205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80242.1"
                     /translation="CQQYNSGPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          115 c          105 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acacagtctc
      121 catcctccct gtcttcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agagaccagg caaagccccg aggcccttga
      241 tctattacgc gtccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtggc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002718             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15152:2635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002718
VERSION     KCVT01002718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15152:2635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..312
                     /note="immunoglobulin light chain variable region"
     V_region        152..312
     V_segment       152..275
                     /gene="IGKV2-88"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80243.1"
                     /translation="CMQSLEIPPTF"
     J_segment       278..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           66 a           88 c           89 g           72 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agccactgat ttcacactga aaatcagcag ggtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa tctctagaga ttcctcccac tttcggtgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01002719             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5426:19967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002719
VERSION     KCVT01002719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5426:19967"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80244.1"
                     /translation="CQQDFDWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          128 c          116 g           91 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac catcacaaac ctgggcaggc
      241 tcccaagctc ctcctctttg gtgcatccac cagggccacc ggcatcccag acaggttcag
      301 tgccagtggg tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt
      361 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01002720             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12794:18686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002720
VERSION     KCVT01002720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12794:18686"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80245.1"
                     /translation="CQKYSDSPLTF"
     J_segment       397..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          100 a          125 c          119 g           93 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat
      121 attgactcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcatctatg gtgcatctag cagggtcact ggcatcccag acaggttccg
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcagtgtat tactgtcaga aatatagtga ctccccgctc actttcggcg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01002721             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13954:18238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002721
VERSION     KCVT01002721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13954:18238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    18..301
                     /note="immunoglobulin light chain variable region"
     V_region        18..301
     V_segment       18..263
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <241..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80246.1"
                     /translation="CMQALDFPWTF"
     J_segment       264..301
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>304
                     /gene="IGKC"
BASE COUNT           74 a           67 c           91 g           72 t
ORIGIN      
        1 atggggactg atcacgactc catctcctgt aggtctagtc agagcctctt ggatagtgag
       61 gatggaaaca cctatttgga atggtacctg cagaagccag ggcagtctcc acaactcttg
      121 atttatgagg tttccgaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca
      181 gacactgatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg ggtttattac
      241 tgcatgcaag ctctggactt tccgtggacg ttcggccaag ggaccaaggt ggaagtcaaa
      301 cgag
//
LOCUS       KCVT01002722             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5616:8524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002722
VERSION     KCVT01002722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5616:8524"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80247.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          118 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 cggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gctagtcagg
      181 acattagtaa ttttttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg ggaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgcg acttatcatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002723             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22970:10523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002723
VERSION     KCVT01002723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22970:10523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80248.1"
                     /translation="CQQGYSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          119 c          104 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctatag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tgacaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatctt
      241 tggggcatcc actttccaaa gtgggactcc ctcgcggttc agcggcagtg aatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt atttctgtca
      361 acagggttat agttaccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01002724             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11007:18490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002724
VERSION     KCVT01002724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11007:18490"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80249.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          104 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002725             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11594:15302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002725
VERSION     KCVT01002725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11594:15302"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80250.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag attccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagagacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002726             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18207:11253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002726
VERSION     KCVT01002726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18207:11253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80251.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          124 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atctggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002727             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16567:12330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002727
VERSION     KCVT01002727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16567:12330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..404
                     /note="immunoglobulin light chain variable region"
     V_region        101..404
     V_segment       101..367
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80252.1"
                     /translation="CQQDFDWPPTF"
     J_segment       370..404
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           97 a          117 c          108 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccagt cagagtgttg gcaacacctt
      181 aacctggtac cagcacaaac ctgggcaggc tcccaagctc ctcctctatg gtgcatccac
      241 cagggcctcc ggcatcccag gcaggttcag tgccagtggg tctggaacag agtttactct
      301 caccatcagc agcctggagc ctgaagatgt tggaatttat tactgtcagc aggattttga
      361 ctggcctccg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01002728             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22090:20371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002728
VERSION     KCVT01002728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22090:20371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80253.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          122 c          121 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccaa gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01002729             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:10637:15411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002729
VERSION     KCVT01002729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10637:15411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..247
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80254.1"
                     /translation="CQQGYNTPWTF"
     J_segment       248..285
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           79 a           73 c           77 g           59 t
ORIGIN      
        1 acatgggagg agacaaagtc accatcactt gccgagccag tcagggtatt agcaggtggt
       61 tagcctggta tcagcagaaa ccagggaaag cccctagact cctgatctat aaggcgtcca
      121 ctttggcaag tggggtccca tcaaccttca gcggcagtgg atctgggacg gattacactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttattgtcaa cagggttaca
      241 ataccccgtg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01002730             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19115:9442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002730
VERSION     KCVT01002730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19115:9442"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80255.1"
                     /translation="CMQAVEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          118 c          119 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctcaatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg ggaacaccta tttgacatgg tacctgaaga agcctggcca
      241 gtctccacag ctcttaattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctgt agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002731             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:8164:14059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002731
VERSION     KCVT01002731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8164:14059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80256.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 cgtcctccct gtctgcatct gtaggagaca gagtcagcat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002732             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20106:18926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002732
VERSION     KCVT01002732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20106:18926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80257.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002733             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10958:16978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002733
VERSION     KCVT01002733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10958:16978"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80258.1"
                     /translation="CLQYKSYPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          115 c          100 g          103 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ttgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 ggttattatc aattatttaa attggtttca gcagaaacca gggaaagccc ctaagctcct
      241 gatttatgct gcatccagat tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tataaaagtt acccattcac tttcggcccc gggaccacac tggatatcaa
      421 acgag
//
LOCUS       KCVT01002734             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20783:7412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002734
VERSION     KCVT01002734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20783:7412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80259.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          124 g          103 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttgtctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 caggctccac agctcttgat ttacgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002735             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20050:11345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002735
VERSION     KCVT01002735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20050:11345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80260.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          120 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc acggtggaga tcaaacgag
//
LOCUS       KCVT01002736             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:7812:15708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002736
VERSION     KCVT01002736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7812:15708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80261.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          109 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcactcttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttcctac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aagatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagag tttcctctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01002737             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22677:21080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002737
VERSION     KCVT01002737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22677:21080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80262.1"
                     /translation="CLQDIQFPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          122 c          121 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgttg actcagactc
      121 cagtctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccttca aactaatgga aacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaagatg
      361 ttggggttta ttactgcttg caagatatac agtttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01002738             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12254:2574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002738
VERSION     KCVT01002738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12254:2574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80263.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002739             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16297:17570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002739
VERSION     KCVT01002739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16297:17570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80264.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          111 c          109 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attattgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002740             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:26068:14558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002740
VERSION     KCVT01002740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:26068:14558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..415
                     /note="immunoglobulin light chain variable region"
     V_region        98..415
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80265.1"
                     /translation="CQQYDSDPYSF"
     J_segment       382..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>422
                     /gene="IGKC"
BASE COUNT          104 a          113 c          112 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattaggagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga aggccttgat
      241 ctattacaca tccattttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgag gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgtacagttt tggccagggg accagagtgg agatccaacg
      421 ag
//
LOCUS       KCVT01002741             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:4184:13381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002741
VERSION     KCVT01002741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:4184:13381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80266.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcagc
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002742             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:13519:3690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002742
VERSION     KCVT01002742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13519:3690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80267.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          116 c          125 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggattg gtacctgcag aagtcaggcc
      241 agtctccaca gcttttgatt tatgaggttt ccaaccgggc ctcgggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tggagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002743             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10762:6326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002743
VERSION     KCVT01002743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10762:6326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..379
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80268.1"
                     /translation="CQQGYNYPFTF"
     J_segment       389..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          123 c          107 g           98 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctccttggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgacgca
      121 gtctccatcc tccctgtccg catctgtagg agacacagtc acgatcactt gccaggcgag
      181 tcaaggcatt ggcactagtt taagttggta tcagcagaaa ccagggaaag cccctaaact
      241 cctgatctat agggcatcca gtttgcaaag tgggattccc tctcggttca gcggcagtgg
      301 atctgggacg gctttcactc tcaccatcag cagcctacag cctgaagatt ttgccactta
      361 ttactgtcaa cagggttata attacccctt cactttcggc cccgggacca aactggatat
      421 caaacgag
//
LOCUS       KCVT01002744             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:9560:9041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002744
VERSION     KCVT01002744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9560:9041"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80269.1"
                     /translation="CLQGYITPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          114 c          112 g           98 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg cgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttgcaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 actgtctaca gggttatatt accccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002745             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17442:8121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002745
VERSION     KCVT01002745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17442:8121"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80270.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           96 a          128 c          111 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac gctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagagctgg tagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcaccctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01002746             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11608:9920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002746
VERSION     KCVT01002746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11608:9920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80271.1"
                     /translation="CQQYNTLITF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          112 c          106 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cgcttgccgg gcaagtcagg
      181 acataagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttatttct
      361 gtcaacagta taacacttta atcactttcg gcgggggaac caaggtggag atcaaacgag
//
LOCUS       KCVT01002747             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16750:11942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002747
VERSION     KCVT01002747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16750:11942"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..384
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80272.1"
                     /translation="CQQYNDFLLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          123 c          112 g           91 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggatcccaga taccgccgga aaaattgtta tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aacagccacc ctctcctgca gggccagtga
      181 gaatgttggc aactacttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 tgtccatagt gcatccttca gggccactgg catcccagac aggttcagtg gcagcgggtc
      301 taggacagag ttcactctca ccattagcag cctggagcct gaagatgttg gactttatca
      361 ctgtcagcaa tataatgact tcctgctcac tttcggcgga gggaccaagg tggaggtcaa
      421 acgag
//
LOCUS       KCVT01002748             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13845:4566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002748
VERSION     KCVT01002748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13845:4566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..429
                     /note="immunoglobulin light chain variable region"
     V_region        93..429
     V_segment       93..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80273.1"
                     /translation="CMQGTHLPFTF"
     J_segment       392..429
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          100 a          120 c          109 g          103 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggc
       61 tgctattgct ctgcgtcccc ggatccagtg gggatgttgt gatgactcag tctccactct
      121 ccctgtctat cactcttgga caaccggcct ccatttcctg caggtctagt cacacccttg
      181 tacacagtga tgggaaaacc tacttgaatt ggtatcagca gaagccaggc caacctccaa
      241 ggcgcctaat ttatcaggtt tctaaccggg actctggggt cccagacaga ttcagcggca
      301 gtggggcagg gacagatttc acactgaaaa tcagcagagt ggaggctgag gatgttggag
      361 tttattactg catgcaaggt acacaccttc cattcacttt cggccccggg accaaactgg
      421 atatcaaacg ag
//
LOCUS       KCVT01002749             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22885:13408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002749
VERSION     KCVT01002749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22885:13408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80274.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattatgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002750             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7900:7427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002750
VERSION     KCVT01002750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7900:7427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80275.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccaacacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002751             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19227:2851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002751
VERSION     KCVT01002751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19227:2851"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80276.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actgtccccg cccgtcaccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002752             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14329:19942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002752
VERSION     KCVT01002752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14329:19942"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80277.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          111 c          113 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctacatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagt tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 gggcagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca agttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002753             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:9975:10286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002753
VERSION     KCVT01002753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:9975:10286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80278.1"
                     /translation="CMQYIHMPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          107 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaagctcc ctgctcagct
       61 cctggggctg ctaatgctct ggctctctgg gtccagtggg gatattgtga tgacccagac
      121 tccactctcc ctgtccgtca cccctggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgaag atggaaacac ctatttggat tgctacctgc agaagccggg
      241 ccagtctcca cagcccttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      301 gttcaatggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctgg
      361 ggatgttggg gtttattact gcatgcaata tatacacatg cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002754             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:21083:13506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002754
VERSION     KCVT01002754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21083:13506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80279.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactaatttc acactgagaa tcagtagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002755             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:25274:4266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002755
VERSION     KCVT01002755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25274:4266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80280.1"
                     /translation="CMQGIQLPPTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           86 a          127 c          123 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctgc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cccggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccaact tagtaatgga tacacctatc tgttttggta cctgcagaag ccgggccagt
      241 ctccacagct cctgatctat ttgctttccg gccgggcctc tggagtccct gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caaggtatac agcttcctcc gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01002756             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20932:4147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002756
VERSION     KCVT01002756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20932:4147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80281.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          123 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacaac
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002757             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19854:16053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002757
VERSION     KCVT01002757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19854:16053"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80282.1"
                     /translation="CQHSYGTPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          114 c          108 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgta ggacaagtca
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagccc ctaggctcct
      241 gatctatgct gcgtccaatt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactttca ccatcaccag cctgcaacct gaagatgttg caacttatta
      361 ctgtcagcat agttatggta ccccgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002758             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18145:14977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002758
VERSION     KCVT01002758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18145:14977"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80283.1"
                     /translation="CQQYNSLPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          109 c          111 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattgag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcgttaa cgtttattta aattggtatc aacagaaacc ggggaaagcc cctaagcccc
      241 tgatctttta tgcaaaccgt ttggaacgtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaagttatt
      361 attgtcaaca gtataatagt ttaccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002759             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:4489:17847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002759
VERSION     KCVT01002759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4489:17847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80284.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggatcacga ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca ggtcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002760             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17708:10029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002760
VERSION     KCVT01002760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17708:10029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80285.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          107 t
ORIGIN      
        1 acatggagtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatacggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002761             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11684:21312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002761
VERSION     KCVT01002761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11684:21312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80286.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatcaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcgga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggaa tttatttctg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002762             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24072:3089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002762
VERSION     KCVT01002762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24072:3089"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80287.1"
                     /translation="CQQFNNLPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct ggaggagaca gcgtcaccat cagttgccgg gcaagtcagg
      181 acattagcac ttatttaaat tggtttcagc agaaaccggg gaaagcccct aagctcctga
      241 tctatgatgg aaaccgtttg gagactgggg tcccatcaag gttcagcggc agtggatccg
      301 ggacagaatt cactctcacc atcaccagcc tgcaacctga agattttgca acttattact
      361 gtcaacagtt taataattta cctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002763             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16652:9637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002763
VERSION     KCVT01002763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16652:9637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80288.1"
                     /translation="CQQYNSDLFTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          102 a          112 c          109 g           95 t
ORIGIN      
        1 acatggggga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catttgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 tacgcgtcca ttttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataaca gtgacctgtt cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002764             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11447:2123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002764
VERSION     KCVT01002764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11447:2123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80289.1"
                     /translation="CQQYNSLPRTF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>420
                     /gene="IGKC"
BASE COUNT          106 a          112 c          108 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cacgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttagtcaata tttaaattgg tatcagcaga aaccggggaa agcccctaag gtcctcatct
      241 attatgtaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tattactgtc
      361 aacagtataa tagtttacct cggacgttcg gccaagggac caaggtggaa atcagacgag
//
LOCUS       KCVT01002765             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:23116:3637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002765
VERSION     KCVT01002765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23116:3637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80290.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          122 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaacccggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgacg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccagggtgga gatcaaacga g
//
LOCUS       KCVT01002766             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14254:11976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002766
VERSION     KCVT01002766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14254:11976"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80291.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002767             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14474:16867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002767
VERSION     KCVT01002767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14474:16867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80292.1"
                     /translation="CYQHSRGWAF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           95 a          125 c          117 g           83 t
ORIGIN      
        1 acatggggga gctgctaggt tagtacccag aaggaaccat ggaagcccca gctcagcttc
       61 tctgccttct gctactctgg ctcccaggca cccccggaca agttatgttg acacagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccactct ctcctgcagg gccagtgaga
      181 atgttggcag ctacttagcc tggtaccagc agaaccctgg gcaggctccc aggctcctca
      241 tccacagtgc gtccagcagg gccactgaca tcccagacag gttcagtggc agtgggtctc
      301 ggacagagtt caccctcacc atcagcagcc tggagcctga agatgttgga gtctattact
      361 gctatcaaca tagcaggggg tgggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01002768             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13291:12199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002768
VERSION     KCVT01002768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13291:12199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80293.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttacgaatga tttagcctgg tatcaacaga aaccaggtaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaagttt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01002769             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22472:5063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002769
VERSION     KCVT01002769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22472:5063"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80294.1"
                     /translation="CQHSYDTPYTF"
     J_segment       407..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          108 a          124 c          114 g          100 t
ORIGIN      
        1 acatggggag gctggtcaca ccctgtgcag gagtcagtct cagtcaggac acagcatgga
       61 catgagggcc tctgctcagc tcctagggct cctgctgctc tggctcccag gcgccagatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgc agggcaagtg cgaacgttaa caactattta cattggtatc agcagaaacc
      241 agggaaagtc cctgagctcc tgatctatgc tgcatcgtct ttgcaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga tttcaccctc accatcagca gcctgcagcc
      361 tgaagatgtt gcaacttatt actgtcagca tagttatgat accccctaca cttttggcca
      421 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01002770             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14734:13295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002770
VERSION     KCVT01002770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14734:13295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80295.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002771             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12763:13208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002771
VERSION     KCVT01002771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12763:13208"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80296.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcgtccat ctcctgtagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002772             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25897:4740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002772
VERSION     KCVT01002772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25897:4740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80297.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc tcctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cattctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccaggcaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01002773             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22310:4355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002773
VERSION     KCVT01002773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22310:4355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80298.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          118 c          117 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgt agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002774             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13264:14407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002774
VERSION     KCVT01002774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13264:14407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..349
                     /note="immunoglobulin light chain variable region"
     V_region        28..349
     V_segment       28..297
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80299.1"
                     /translation="CLQGDTAPFTF"
     J_segment       314..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           88 a           91 c           93 g           80 t
ORIGIN      
        1 acatgggggc tcccaggtgc cagatgtgac atccagatga cccagtctcc atcttccctg
       61 tctgcatcgg caggagacag agtcaccatc acttgccggg caagtcaggg cattaacgat
      121 tatttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat ttatgctgca
      181 tccagtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc
      241 actctcacca tcagcagcct gcagcctgaa gattttgcag cttattactg tctacagggt
      301 gatactgccc cgttcacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002775             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13054:18909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002775
VERSION     KCVT01002775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13054:18909"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80300.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          119 c          106 g           86 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcacagcc agccacgata
      181 taaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcgaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tttcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01002776             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:8830:7315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002776
VERSION     KCVT01002776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8830:7315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..390
                     /note="immunoglobulin light chain variable region"
     V_region        99..390
     V_segment       99..353
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <330..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80301.1"
                     /translation="CMQALEFPWTF"
     J_segment       354..390
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>393
                     /gene="IGKC"
BASE COUNT           88 a          108 c          109 g           88 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag
      301 tggaggctga ggatgttggt atttattact gcatgcaagc tctagagttt ccttggacgt
      361 tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002777             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20893:20207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002777
VERSION     KCVT01002777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20893:20207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80302.1"
                     /translation="CQQGYNTPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          115 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 atattagcag ctggttagcc tggtatcagc tgaagccggg gaaagcccct aaactcttga
      241 tctataaggc atccagtttg gcaagagggg tcccatcgag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcagtagcc tgcagcctga agattttgca acttattatt
      361 gtcaacaggg ttacaatacc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002778             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:23499:13595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002778
VERSION     KCVT01002778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23499:13595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..352
                     /note="immunoglobulin light chain variable region"
     V_region        131..352
     V_segment       131..315
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <292..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80303.1"
                     /translation="CQQNSNWPLTF"
     J_segment       316..352
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>355
                     /gene="IGKC"
BASE COUNT           85 a          104 c           95 g           71 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctggtacca acaaagacct gggcaggctc ccaggctcct catctatggt
      181 gcatccacca gggccactgg catcccagac aggttcagtg gcagtgggtc tgggacagac
      241 ttcactctca ccatcaccag cctggagcct gacgatgttg cagtttatta ttgtcagcag
      301 aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002779             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:25477:5810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002779
VERSION     KCVT01002779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25477:5810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80304.1"
                     /translation="CQQYNSDPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          115 c          108 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gcagaaacca ggaaaagccc cgaaggcctt
      241 gatctattac gcatccattt tagaaagtgc ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagtct gacgattttg cagtttatta
      361 ctgtcaacag tataacagtg acccgtacac ttttggcccg gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002780             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11847:7309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002780
VERSION     KCVT01002780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11847:7309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..256
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <234..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80305.1"
                     /translation="CIQALEFPWTF"
     J_segment       257..294
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>297
                     /gene="IGKC"
BASE COUNT           72 a           66 c           88 g           71 t
ORIGIN      
        1 acatgggggc ctccatctcc tgcaggtcta gtcagagcct cttggatagt gaggatggaa
       61 atacctattt ggagtggtat ctgcagaagc caggccagtc tccacagctc ttgatttatg
      121 aggtttccaa ccgggcctct ggagtcccag agaggttcag tggcagtggg tcagacactg
      181 atttcacact gaaaatcagc agagtggagc ctgaggatgt tggggtttat tactgcatcc
      241 aagctctaga gtttccgtgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01002781             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18958:15950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002781
VERSION     KCVT01002781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18958:15950"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80306.1"
                     /translation="CQQYDSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          114 c          113 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt atgacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002782             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:9276:6749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002782
VERSION     KCVT01002782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9276:6749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80307.1"
                     /translation="CQQRYRFPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           95 a          113 c          113 g          103 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagtt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggccagtcag
      181 ggcattagca attatttagc ctggtatcag cagaaagtag gaaaagcccc taacctcctg
      241 atctataagg cgtccagttt gcagactggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc agtttattac
      361 tgtcaacagc gttataggtt cccgctcact ttcggtggag ggaccagggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002783             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10789:10558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002783
VERSION     KCVT01002783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10789:10558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80308.1"
                     /translation="CQQGHSYPWTF"
     J_segment       384..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>424
                     /gene="IGKC"
BASE COUNT           99 a          117 c          112 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca gtcgagtcta
      181 ggcattggca aatttttaaa ttggtatcag cagaaaccag ggaaagcccc caaactcctg
      241 atctataggg catccagttt gcaaactggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cgcttattac
      361 tgtcaacagg gtcatagtta cccgtggacg ttcggccaag ggaccaaggt ggagatgaaa
      421 cgag
//
LOCUS       KCVT01002784             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:21201:10976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002784
VERSION     KCVT01002784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21201:10976"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80309.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcaaca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002785             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8496:17875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002785
VERSION     KCVT01002785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8496:17875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80310.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          121 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002786             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10695:10433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002786
VERSION     KCVT01002786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10695:10433"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80311.1"
                     /translation="CIQPLDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          123 c          116 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtctgaca ctgatttcac actgaaaatc agcagagtgg agcctgagga
      361 tgttggggtt tattgctgca ttcaacctct agactttccg tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002787             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16651:9648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002787
VERSION     KCVT01002787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16651:9648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..367
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80312.1"
                     /translation="CQQHYGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcattat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01002788             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19984:13613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002788
VERSION     KCVT01002788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19984:13613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..377
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80313.1"
                     /translation="CQHSYGTLTWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          117 c          108 g           92 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgcgg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gggacagagt caccatcact tgcaggacaa gtgagaacgt
      181 taagaactat ttacattggt atcagcaaaa accagggaaa gccccaaggc tcctgatata
      241 tgctgcatcc actttgcaaa gtggggtccc atcaaggttc accggcagtg gatctggggc
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcgactt attactgtca
      361 acatagttat ggtaccctca cgtggacgtt cggccacggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002789             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16580:10334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002789
VERSION     KCVT01002789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16580:10334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80314.1"
                     /translation="CQQDYDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          121 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agatacagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcacctta gtatggtacc accagaaacc tgggcaggct cccacgctcc
      241 tcgtctatgg tacatccatc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagac tgaagatatt ggagtttatt
      361 attgtcagca ggattatgat tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002790             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22626:5764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002790
VERSION     KCVT01002790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22626:5764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80315.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          117 c          106 g           89 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcacagcc agtcagggta
      181 ttaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaaa ctccttatct
      241 atagggcatc caatttggaa acaggggtcc catcgaggtt cggtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tatttctgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01002791             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22464:6814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002791
VERSION     KCVT01002791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22464:6814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80316.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002792             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10658:7405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002792
VERSION     KCVT01002792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10658:7405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80317.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002793             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20499:6635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002793
VERSION     KCVT01002793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20499:6635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80318.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          110 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacactttaa cctggtatca ccacaagcct ggacaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002794             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11553:19137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002794
VERSION     KCVT01002794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11553:19137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80319.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcaggggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01002795             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8447:15483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002795
VERSION     KCVT01002795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8447:15483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80320.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002796             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:9826:8506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002796
VERSION     KCVT01002796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:9826:8506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80321.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagc ccttaatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agaggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002797             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23115:10837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002797
VERSION     KCVT01002797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23115:10837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80322.1"
                     /translation="CQQYNNDPPTF"
     J_segment       382..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          122 c          102 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcgtctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagcagtcat ttagcgtggt atcagcagag accagggaaa gccccgaagc ccttgatcta
      241 ttacgcatcc aatttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gtagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac aatgaccctc ccactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01002798             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24749:14368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002798
VERSION     KCVT01002798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24749:14368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..377
                     /note="immunoglobulin light chain variable region"
     V_region        80..377
     V_segment       80..330
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80323.1"
                     /translation="CQQHNGYPPTF"
     J_segment       343..377
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>380
                     /gene="IGKC"
BASE COUNT           94 a          108 c           95 g           83 t
ORIGIN      
        1 acatggggtc agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattacga atgatttagc
      181 ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg atctattacg catcaaggtt
      241 cagcggcagt ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga
      301 ttttgcaact tattattgtc aacagcataa tggataccct ccgacgttcg gccaagggac
      361 cagggtggaa atcaaacgag
//
LOCUS       KCVT01002799             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24564:5695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002799
VERSION     KCVT01002799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24564:5695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..397
                     /note="immunoglobulin light chain variable region"
     V_region        58..397
     V_segment       58..360
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <337..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80324.1"
                     /translation="CMQSLEIPPTF"
     J_segment       363..397
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>400
                     /gene="IGKC"
BASE COUNT           86 a          105 c          113 g           96 t
ORIGIN      
        1 acatgggctg ctcagctcct gggactgcta atgctctggc tccctggatc cagtggggac
       61 attgtgatga cccagactcc actctccctg cccgtcaccc ttggagagcc ggcctccatc
      121 tcctgcaggt ctagtcagag cctcttggat agtggggatg gaaacaccta tttggattgg
      181 tacctgcaga agccaggcca gtctccacag ctcttgattt atgaggtttc caaccgggcc
      241 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      301 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaatctct agagattcct
      361 cccactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01002800             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17214:10829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002800
VERSION     KCVT01002800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17214:10829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80325.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccagggc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002801             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17476:20212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002801
VERSION     KCVT01002801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17476:20212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..413
                     /note="immunoglobulin light chain variable region"
     V_region        96..413
     V_segment       96..380
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80326.1"
                     /translation="CQQGYNYPWTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>420
                     /gene="IGKC"
BASE COUNT          100 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgtg ggagacacag tcacgatctc ttgccaggcg agtcaaggca
      181 ttgacaagaa tttaaattgg tttcagcaga caccagggaa agcccctaaa ctcctgatct
      241 ataagacatc cagtttgcag agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta taattacccg tggacgttcg gccaagggac caaggtggaa atccaacgag
//
LOCUS       KCVT01002802             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:9022:11855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002802
VERSION     KCVT01002802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9022:11855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80327.1"
                     /translation="CQQDYDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          120 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agatacagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagggccac cctctcctgc agggccagtc
      181 agagtgttgg cagcacctta gtatggtacc accagaaacc tgggcaggct cccaagctcc
      241 tcgtctatgg tacatccatc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagac tgaagatatt ggaatttatt
      361 attgtcagca ggattatgat tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002803             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17593:15966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002803
VERSION     KCVT01002803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17593:15966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80328.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgtatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002804             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11191:14185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002804
VERSION     KCVT01002804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11191:14185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80329.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 ctgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01002805             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8682:8456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002805
VERSION     KCVT01002805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8682:8456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..433
                     /note="immunoglobulin light chain variable region"
     V_region        98..433
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80330.1"
                     /translation="CMQALEFPRTF"
     J_segment       402..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>440
                     /gene="IGKC"
BASE COUNT           95 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgtatc cagtggtgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgcggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt ggctcagaca ctgatttcac actgaaaatc agcagagtgg aggctgaaga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct cggacgttcg gccaggggac
      421 caaggtggaa atcgaacgag
//
LOCUS       KCVT01002806             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18468:10865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002806
VERSION     KCVT01002806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18468:10865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80331.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tacagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01002807             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:2046:10424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002807
VERSION     KCVT01002807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:2046:10424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..388
                     /note="immunoglobulin light chain variable region"
     V_region        67..388
     V_segment       67..350
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <328..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80332.1"
                     /translation="CLQGYITPYSF"
     J_segment       351..388
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>391
                     /gene="IGKC"
BASE COUNT           89 a          104 c          102 g           96 t
ORIGIN      
        1 acatgggtga gggtccccgc tcagctcctg gggctccttc tgctctggct cccaggtgcc
       61 agatgtgact tccagatgac ccagtctcca tcttccctgt ctgcatcggt aggagacaga
      121 gtcaccatca cttgccgggc aagtcaggac attagcgatt ttttaagttg gtatcagcag
      181 aaaccaggaa aacctcctaa gcgcctgatt tatgctgcat ccagtttgca aagtggggtc
      241 ccgtcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat cagcagcctg
      301 cagcctgaag attttgcggc ttattactgt ctacagggtt atattacccc gtacagtttt
      361 ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01002808             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22284:6285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002808
VERSION     KCVT01002808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22284:6285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80333.1"
                     /translation="CQQYNNSPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          110 c          108 g           97 t
ORIGIN      
        1 acatgggggg agtcagtccc attcaggaca cagcatggac atgagggtcc ccactcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 ggacattgac agttatttga gttggtatca gcagaaacca gggaaagccc ctaagcccct
      241 gatctattat acatccagtt tgcaaacagg ggtaccgtca aggttcagtg gaagtcgatc
      301 tgggacagat tatagtctca ccatcagcag tctgcagcct gaagattttg caacatatta
      361 ctgtcaacag tataataatt ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002809             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13480:8083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002809
VERSION     KCVT01002809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13480:8083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..380
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80334.1"
                     /translation="CQQSYRYPLTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           97 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggac acagcatgga catgagggcc tctgctcagc
       61 tcctagggct cctgctgctc tggctcccag gcgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agggcaagtg
      181 agaacgttaa caactattta cattggtatc agcagaaacc agggaaagcc cctaaactcc
      241 tgatgtatct tgcatccact ttgcagagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc gccatcagca gcctgcagcc tgaagatgct gcaacttatt
      361 actgtcagca gagttatcgt tatccgctca ctttcggtgg agggacccag gtggaaatca
      421 atcgag
//
LOCUS       KCVT01002810             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19347:20167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002810
VERSION     KCVT01002810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19347:20167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80335.1"
                     /translation="CLHYNSDPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          111 a          110 c          108 g          101 t
ORIGIN      
        1 acatggggga agttagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagc tcaggtgcca gatgtgacat ccagatgacc
      121 cagtctccat cttccctgtc tgcatctgta agagacagag tcaccttcac ttgcagggca
      181 agtcagggca ttacaactta tttaaattgg tgtcagcaga aatcaggaaa aactcctaag
      241 cgcctgatct gtgttgaaaa cagtttggaa agtggggtcc catcaaggtt cagtggcagt
      301 ggatctggga caggtttcac tctcaccatc agcagcctgc agcctgaaga ttttacacct
      361 tattactgtc ttcattataa cagtgacccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01002811             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12128:18774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002811
VERSION     KCVT01002811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12128:18774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80336.1"
                     /translation="CLQGYNIPYNF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          110 c          110 g           98 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagttga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tatttaagtt ggtatcagca gaaaccagga aaagctccta agcgcctgat
      241 ctatgctgtg tccagtttgg aaggtggggt cccatcaaga ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcga cttattactg
      361 tctacagggt tataatatcc cgtacaattt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002812             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18941:13731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002812
VERSION     KCVT01002812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18941:13731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80337.1"
                     /translation="CQQYDSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          112 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgctgggcaa gtcagggcat
      181 tgacaattat ttaaattggt atcaggagac accggggaaa gcccctaagc ccctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagta gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtatgat tctttaccgt ggacgttcgg ccaagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01002813             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11958:21610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002813
VERSION     KCVT01002813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11958:21610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80338.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acacctcttg atttatgaag tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002814             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14341:6331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002814
VERSION     KCVT01002814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14341:6331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80339.1"
                     /translation="CQQHDNSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          121 c          109 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      181 ccacgatata aatatctggt tggcctggta tcaacagaaa ccaggaaaag cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttca gtggaagtgg
      301 atctgggaca gatttcaccc tcaccatcag cagcctgcag cctgaagatt tcgcaacata
      361 ttactgtcaa cagcatgata attcccctcg gacgttcggc caagggacca aggtggaagt
      421 caaacgag
//
LOCUS       KCVT01002815             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18031:4929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002815
VERSION     KCVT01002815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18031:4929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80340.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaacct attactgtca
      361 acagtatgac agtgatccgt tcactttcgg tggggggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01002816             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14500:4040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002816
VERSION     KCVT01002816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14500:4040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80341.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcaatg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002817             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:24944:19158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002817
VERSION     KCVT01002817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24944:19158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80342.1"
                     /translation="CQRYSYSTWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          120 c          115 g           92 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccattc
      181 agagtgttgg cagcagcttg gtttggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtatatt
      361 actgtcagag gtatagttac tccacgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002818             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18746:18147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002818
VERSION     KCVT01002818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18746:18147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80343.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          126 c          109 g          101 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga aattttgatg acccagactc
      121 cactttcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaacgga tacacctact tgcattggta cctgcagaag ccaggccagc
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggacg
      361 ttggtattta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01002819             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9121:11779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002819
VERSION     KCVT01002819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9121:11779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80344.1"
                     /translation="CQQGNGLPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          108 c          109 g          104 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcgtccct gtctgctttt gtaggagaca gagtcaccat cagttgccgg gcaagtcagg
      181 ccattagtag ttctttatat tggtatcagc agaaaccggg gaaagcccct aaacttctga
      241 tttataaggc atatcttttg gaagatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcact atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacaggg taatggttta ccattcactt tcggccccgg gaccaaagtg gatgtcaaac
      421 gag
//
LOCUS       KCVT01002820             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11091:10549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002820
VERSION     KCVT01002820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11091:10549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..437
                     /note="immunoglobulin light chain variable region"
     V_region        102..437
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80345.1"
                     /translation="CMQALEFPRTF"
     J_segment       406..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>444
                     /gene="IGKC"
BASE COUNT           96 a          124 c          119 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg tatccagtgg tgacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgcg gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tctccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtggctca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aagatgttgg gatttattac tgcatgcaag ctctagagtt tcctcggacg ttcggccagg
      421 ggaccaaggt ggaaatcgaa cgag
//
LOCUS       KCVT01002821             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25764:22417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002821
VERSION     KCVT01002821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25764:22417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80346.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttataactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002822             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10253:11747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002822
VERSION     KCVT01002822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10253:11747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80347.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          126 c          112 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttcgaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002823             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16538:13219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002823
VERSION     KCVT01002823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16538:13219"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80348.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01002824             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15043:18559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002824
VERSION     KCVT01002824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15043:18559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80349.1"
                     /translation="CLQYKSFPYTF"
     J_segment       385..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          108 a          115 c           97 g           98 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtggg agacactgtc accatcactt gccggacaag tcaaggtatt
      181 accaattatt tacattggtt tcagcagaaa ccagggagag cccctaagct cctgatctat
      241 gaaacattca gtttgacaag tggggtccca tcaaggttca gcggcagtgc atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa gtttcccgta cacctttggc caggggacca aactggagat caaacgag
//
LOCUS       KCVT01002825             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21278:11881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002825
VERSION     KCVT01002825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21278:11881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80350.1"
                     /translation="CMQSLEIPPSF"
     J_segment       406..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cgcagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cacccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggcgtt tattactgca tgcaatctct agagattcct cccagtttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002826             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:24209:14481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002826
VERSION     KCVT01002826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24209:14481"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80351.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          105 a          125 c          119 g           87 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct
      241 cccagactcc tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt
      301 ggcagtgggt ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt
      361 gcactttatt attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01002827             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:3399:8794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002827
VERSION     KCVT01002827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3399:8794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80352.1"
                     /translation="CQQGDSYPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          111 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg tcagatgtga cattcagatg tcccagtctc
      121 cttcctccct gtctgcatct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagaga ttatttaaat tggtatcagc agcaaccggg gaaagcccct aaactcctga
      241 tgtattatgc aaacagtctg gcaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg tgacagttat cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002828             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15281:11250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002828
VERSION     KCVT01002828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15281:11250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80353.1"
                     /translation="CMQALDFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg ctagtgagga tggaaacacc tatttggagt ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgatgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcaacagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagactttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002829             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:26190:5755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002829
VERSION     KCVT01002829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26190:5755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..364
                     /note="immunoglobulin light chain variable region"
     V_region        43..364
     V_segment       43..326
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80354.1"
                     /translation="CQQYNSDPYTF"
     J_segment       327..364
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           91 a           94 c           94 g           88 t
ORIGIN      
        1 acatggggac tcctgctgct ctgtctccca ggtgccaatt gtgacatcca ggtgacccag
       61 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgagt
      121 cagggcatta gaagttattt agcgtggtat cagctgagac cagggaaagc cccgaaggcc
      181 ttaatctatt acgcgaccat tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tttgggacag aattcactct caccatcaac agcctgcagc ctgaggattt tgcaacttat
      301 ttctgtcaac agtataacag tgacccgtac acttttggcc aggggaccaa agtggagatc
      361 aaacgag
//
LOCUS       KCVT01002830             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10353:17202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002830
VERSION     KCVT01002830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10353:17202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80355.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          116 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc accagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01002831             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18563:3241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002831
VERSION     KCVT01002831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18563:3241"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80356.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          116 c          108 g           88 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagga
      181 tattaacaac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aggtcctgat
      241 ctatagggca tccattttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002832             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4461:17741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002832
VERSION     KCVT01002832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4461:17741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80357.1"
                     /translation="CQQNSNWPLTF"
     J_segment       390..426
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          101 a          122 c          120 g           86 t
ORIGIN      
        1 acatgggggg ggaggaactg ctcagttagg acccagaggg aaccatggaa gccccagcac
       61 agcttctctt cctcctgctg ctctggctcc cagataccac cggagaaata gtgatgacgc
      121 agtctccagc caccctgtct ttgtctccag gagaaagagc caccctctcc tgcagggcca
      181 gtcagagtgt cagcagcagc ttagcctggt accagcagaa acctgggcag gctcccaggc
      241 tcctcatcta tggtgcatcc aacagggcca ctggcatccc agacaggttc agtggcagtg
      301 ggtctgggac agagttcact ctcaccatca gcagcctgga gcctgaagat gttgcagttt
      361 attattgtca gcagaatagt aactggcctc tcactttcgg tggagggacc aaggtggaga
      421 tcaaacgag
//
LOCUS       KCVT01002833             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19727:9517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002833
VERSION     KCVT01002833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19727:9517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80358.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat catcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002834             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12879:13764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002834
VERSION     KCVT01002834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12879:13764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80359.1"
                     /translation="CMQTLEFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaggctcttg gatagtgagg atgaaaacac ctacttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaaac tctagagttt ccattcactt tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01002835             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18697:13197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002835
VERSION     KCVT01002835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18697:13197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80360.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          117 c          109 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 gatattaaca cctggttggc ctggtatcaa cagaagccag ggaaagcccc taaggtcctg
      241 atctatagga catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcaacagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002836             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:10142:8986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002836
VERSION     KCVT01002836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10142:8986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80361.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcattg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002837             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17343:9684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002837
VERSION     KCVT01002837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17343:9684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80362.1"
                     /translation="CMQGLEFPPTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggcga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggtgat ggaaacacct atttggaatg tttcctccag aggccaggcc
      241 agtctccaca cctcttgatt tatggggctt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tccgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002838             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:13553:8305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002838
VERSION     KCVT01002838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13553:8305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80363.1"
                     /translation="CLQGYNTPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagaggt gacatccagt tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacctgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gtgtccagtt tggaaggtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagatcttg cgacttatta
      361 ctgtctacag ggttataata ccccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002839             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19017:10691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002839
VERSION     KCVT01002839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19017:10691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80364.1"
                     /translation="CQQHADSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          118 c          109 g           89 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcaggg
      181 tattagcaac tggttggcct ggtatcaaca gagaccaggg aaagccccta aggtcctgat
      241 ttataggaca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa ccggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatttcgcta catattactg
      361 tcaacagcat gctgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002840             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16169:13739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002840
VERSION     KCVT01002840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16169:13739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80365.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          117 c          109 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagtcag
      181 ggtattaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcggtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002841             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:27045:8265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002841
VERSION     KCVT01002841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:27045:8265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80366.1"
                     /translation="CQQHDNSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          120 c          108 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagcca
      181 cgatataaat atctggttgg cctggtatca acagaaacca ggaaaagccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcagtg gaagtggatc
      301 tgggacagat ttcaccctca ccatcagcag cctgcagcct gaagatttcg caacatatta
      361 ctgtcaacag catgataatt cccctcggac gttcggccaa gggaccaagg tggaagtcaa
      421 acgag
//
LOCUS       KCVT01002842             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21563:11242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002842
VERSION     KCVT01002842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21563:11242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80367.1"
                     /translation="CQQDFDWPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           97 a          127 c          109 g           90 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagctcca gcacagcttc
       61 tcttcctcct gctactctgg atcccagata ccaccggaga agttgtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcaa caccttaacc tggtaccttc acaaacctgg gcaggctccc aagctcctcc
      241 tctttggtgc atccaccagg gccaccggca tcccagacag gttcagtgcc agtgggtctg
      301 gaacagactt tactctcacc atcagcagcc tggagcctga ggatgttgga atttattact
      361 gtcagcagga ttttgactgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01002843             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18914:13582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002843
VERSION     KCVT01002843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18914:13582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80368.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttaatt tatgagcttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002844             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13188:12438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002844
VERSION     KCVT01002844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13188:12438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80369.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagaccc
      121 cagtctccct acccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctctggga cagtgaggat ggaagcacct ttttggaatg gtatctgcag aagccaggcc
      241 agtctccaca actcttgatt tctgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcactggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcagacga g
//
LOCUS       KCVT01002845             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:11093:17331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002845
VERSION     KCVT01002845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11093:17331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80370.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggtc
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggaggggcc aaggtagaga tcaaacgag
//
LOCUS       KCVT01002846             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17734:23561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002846
VERSION     KCVT01002846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17734:23561"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80371.1"
                     /translation="CQQYDSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          112 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002847             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18568:9351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002847
VERSION     KCVT01002847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18568:9351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80372.1"
                     /translation="CVQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          108 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcgttcaagc tcttgagttt ccgtggactt tcggccaagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01002848             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:23059:9880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002848
VERSION     KCVT01002848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23059:9880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80373.1"
                     /translation="CMQALEFPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          125 c          117 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga taatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccattcac cttcggcccc
      421 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01002849             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19987:15191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002849
VERSION     KCVT01002849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19987:15191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80374.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgt ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002850             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9256:14942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002850
VERSION     KCVT01002850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9256:14942"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80375.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002851             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8028:17096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002851
VERSION     KCVT01002851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8028:17096"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80376.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg gtgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaagctcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002852             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12135:14297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002852
VERSION     KCVT01002852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12135:14297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80377.1"
                     /translation="CQQYNSGPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          117 c          101 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag taaccatcac ttgtcgggcg agtcaggaca
      181 taagaagtta tttagcgtgg tatcagcaga aaccagccaa agccccgaag cccttgatct
      241 attacgcatc cgttttggaa agtggggtcc catcaaggtt cagtgccagt ggatctggga
      301 cagaattcac tctcaccatc agcagtctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtggccca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01002853             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:16475:20067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002853
VERSION     KCVT01002853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16475:20067"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80378.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          122 c          106 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 taggagttat ttagcgtggt accagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ctacgcatcc attttggcaa ctggggtccc atctaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atcactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aagctgggtg tcaaacgag
//
LOCUS       KCVT01002854             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19996:15057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002854
VERSION     KCVT01002854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19996:15057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..426
                     /note="immunoglobulin light chain variable region"
     V_region        93..426
     V_segment       93..388
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80379.1"
                     /translation="CLQSKNSPWTF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           99 a          114 c          113 g          103 t
ORIGIN      
        1 acatggggca gcctctagtt cagctctcag aaatggggtc ctgggctcct ttcctgtgga
       61 tcctcctgct ctgtgctcca ggatgcaatg gggacattgt gctgacccag tctccagcct
      121 ctttggccgt gtctccaggg cagagggcca ccatcacctg cagacccagt gggagtgtca
      181 gtttgtttgg aataagcctc attcactggt atcagcagaa accaggacaa cctcctaaac
      241 tcctgattta ccaagcattc aatacagaga ctggggtccc agtcaggttc agcggcagtg
      301 ggtctgggac cgatttcacc ctcacaatta atcctgtgga agctgacgat gctgcagatt
      361 atttctgtct gcagagtaaa aattctccgt ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01002855             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4933:21812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002855
VERSION     KCVT01002855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4933:21812"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80380.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacaactctt gatttatgag gtttcctatc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaattagcag agtggaggct
      361 gaggatgttg gggtttttta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002856             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17887:12087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002856
VERSION     KCVT01002856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17887:12087"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80381.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          116 c          109 g           89 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagtca
      181 ggatattaat aactggttgg cctggtatca acagaaacca ggaaaagccc ctaaactcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcggtg gaagtggatc
      301 tgggacagat ttcactctca ccattagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002857             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:9125:8065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002857
VERSION     KCVT01002857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9125:8065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80382.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc ctcggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaagctc tagaatttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002858             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9161:14192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002858
VERSION     KCVT01002858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9161:14192"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80383.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattttgatg acccagactc
      121 cactctccct gcccgtcagc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcaa aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcaaagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01002859             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17972:16050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002859
VERSION     KCVT01002859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17972:16050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80384.1"
                     /translation="CLQYKSFPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          116 c           95 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagcg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacttttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01002860             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9757:20423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002860
VERSION     KCVT01002860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9757:20423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80385.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaca aaccaggcca
      241 gtctccagag ctcttgattt atgaggtttc caagcgggcc tcaggtttcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggctt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag gtcaaacgag
//
LOCUS       KCVT01002861             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15226:7098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002861
VERSION     KCVT01002861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15226:7098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..235
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <212..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80386.1"
                     /translation="CIQSLEFPWTF"
     J_segment       236..272
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>275
                     /gene="IGKC"
BASE COUNT           69 a           58 c           79 g           69 t
ORIGIN      
        1 acatgggagt cacagcctct tggatagtga ggatggatat atccatttgg attggtatct
       61 gcagaagcca ggccagtctc cacacctctt gatttatgag gtttccaacc gggcctctgg
      121 agtcccagac aggtttagtg gcagtgggtc agacactgat ttcacactga aaatcagcag
      181 ggtggaggct gaggatgttg gggtttacta ctgcatacaa tctctagagt ttccttggac
      241 gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002862             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17533:12238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002862
VERSION     KCVT01002862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17533:12238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80387.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtatctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002863             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19735:9188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002863
VERSION     KCVT01002863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19735:9188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80388.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          117 c          127 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgaccctggc
      121 tccagtctcc ctgcccgtca ccctgggaga gccggcctcc atgtcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggcacctgc agaggccagg
      241 ccagtctcca cagctcttga tttatgaggt ttcctatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002864             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7551:10657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002864
VERSION     KCVT01002864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7551:10657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80389.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcgcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002865             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7284:9734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002865
VERSION     KCVT01002865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7284:9734"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80390.1"
                     /translation="CQQYDSDTRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          114 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggccac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cacgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002866             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:27760:16489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002866
VERSION     KCVT01002866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:27760:16489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80391.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacaactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01002867             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11382:19639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002867
VERSION     KCVT01002867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11382:19639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80392.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002868             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20623:6409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002868
VERSION     KCVT01002868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20623:6409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80393.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcgca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002869             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22402:10263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002869
VERSION     KCVT01002869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22402:10263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80394.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac tcactcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01002870             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:27992:7303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002870
VERSION     KCVT01002870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:27992:7303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80395.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          111 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttggaactt attactgtca
      361 acagtatgac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002871             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24209:16562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002871
VERSION     KCVT01002871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24209:16562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80396.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          107 g           88 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01002872             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15599:2685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002872
VERSION     KCVT01002872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15599:2685"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80397.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatgggaga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcaactta gcctggtacc agcagagacc tgggcagtct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002873             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10790:15460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002873
VERSION     KCVT01002873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10790:15460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80398.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagtcaggcc
      241 agtccccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002874             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16555:20271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002874
VERSION     KCVT01002874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16555:20271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80399.1"
                     /translation="CQQYESDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          113 c          110 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aaggccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagtagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgaaagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002875             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20056:14556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002875
VERSION     KCVT01002875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20056:14556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80400.1"
                     /translation="CMQPLEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          119 c          124 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactgt ccctgcccgt cacccttgga gagccggcct ccatctcctg tgggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa cctctagagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002876             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18605:4527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002876
VERSION     KCVT01002876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18605:4527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80401.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002877             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16457:15997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002877
VERSION     KCVT01002877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16457:15997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80402.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcgggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002878             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17067:11356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002878
VERSION     KCVT01002878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17067:11356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80403.1"
                     /translation="CHQGYSYPWTF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          109 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc agtttggaaa gtgggattcc ctctcggtac agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 ccagggttat agttacccgt ggacgttcgg ccaagggacc aaggtggaaa tcaatcgag
//
LOCUS       KCVT01002879             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20705:16702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002879
VERSION     KCVT01002879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20705:16702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..361
                     /note="immunoglobulin light chain variable region"
     V_region        82..361
     V_segment       82..323
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <301..>333
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80404.1"
                     /translation="CQKYSSSPFTF"
     J_segment       326..361
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        362..>364
                     /gene="IGKC"
BASE COUNT           83 a          103 c          100 g           78 t
ORIGIN      
        1 acatgggggc tgctcagtta ggacccagag agaaccatgg aaatcccagc tcagcttctc
       61 ttcctcctgc tactgtggct cccaggggaa agagccatcc tctcctgcag gaccagtcag
      121 agtgttggca ccagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      181 atctatggtg catctagcag ggtcactggc atcccagaca ggttccgtgg cagtgggtct
      241 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtttattac
      301 tgtcagaaat atagtagctc cccgttcact ttcggcggag ggaccaaggt ggagatcaaa
      361 cgag
//
LOCUS       KCVT01002880             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16774:11742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002880
VERSION     KCVT01002880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16774:11742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80405.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002881             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10532:4445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002881
VERSION     KCVT01002881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10532:4445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..429
                     /note="immunoglobulin light chain variable region"
     V_region        97..429
     V_segment       97..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80406.1"
                     /translation="CLQSKTSPYTF"
     J_segment       392..429
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           99 a          120 c          109 g          104 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca atgggaacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgacagtg
      181 tcagtttctt gggattaaac ctcattcact ggtatcagca gaaacctgga caacctccta
      241 aactcctgat ttatcaggca tccaataaag acactgcggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttgatcctgt ggaagctgac gatactgcag
      361 attattactg tctgcagagt aagacttctc cgtacacttt tggccagggg accaaagtgg
      421 acatcaaacg ag
//
LOCUS       KCVT01002882             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23688:6907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002882
VERSION     KCVT01002882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23688:6907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80407.1"
                     /translation="CMQGTHLPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          118 c          117 g          101 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cgggtccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acaaccggcc tccatttcct gcaggtctag tcaaagcctt
      181 gtacacagtg atgagaatac ctacttgaat tggtatcagc tgaagccagg ccaacctcca
      241 aggcgcctaa tttatctggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaga atcagcagag tggaggctga ggatgttgga
      361 ctttattact gcatgcaagg tacacacctt ccgtacagtt ttggccaggg gaccgaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01002883             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21658:8581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002883
VERSION     KCVT01002883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21658:8581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80408.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          110 c          102 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tttattatac aaatcgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01002884             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20280:7194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002884
VERSION     KCVT01002884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20280:7194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80409.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          106 a          124 c          119 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctact ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagtgt agcctggtac cagcaaaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01002885             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6231:18213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002885
VERSION     KCVT01002885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6231:18213"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80410.1"
                     /translation="CLQDIQLPLTF"
     J_segment       401..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           87 a          125 c          120 g          107 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattgtgat gactcagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc ataggaatgg atacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacagc tcctgatcta tttgggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgttt gcaagatata cagcttcctc tcactttcgg ccccgggacc
      421 aaactggaga tcaaacgag
//
LOCUS       KCVT01002886             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:7928:5155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002886
VERSION     KCVT01002886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:7928:5155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..358
                     /note="immunoglobulin light chain variable region"
     V_region        98..358
     V_segment       98..311
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80411.1"
                     /translation="CQQHNGYPPTF"
     J_segment       324..358
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>361
                     /gene="IGKC"
BASE COUNT           87 a          102 c           93 g           79 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 tattacgcat ccaatttgga aagtggggtc ccatcaaggt tcagctgcag tggatctggg
      241 acagatttca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattattgt
      301 caacagcata atggataccc tccgacgttc ggccaaggga ccagggtgga aatcaaacga
      361 g
//
LOCUS       KCVT01002887             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16716:10567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002887
VERSION     KCVT01002887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16716:10567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80412.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          124 g          100 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct gatgctctgg gtccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gccgcttgga cagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac accgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002888             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:12800:3930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002888
VERSION     KCVT01002888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12800:3930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80413.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgccc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002889             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24708:9954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002889
VERSION     KCVT01002889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24708:9954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80414.1"
                     /translation="CTQGLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgacgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggac ttattactgc acacaaggtc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002890             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12455:10019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002890
VERSION     KCVT01002890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12455:10019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80415.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaacc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002891             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12132:18741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002891
VERSION     KCVT01002891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12132:18741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80416.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          117 c          106 g           90 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagtcaggg
      181 tattaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta aactccttat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcggtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catatttctg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002892             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12033:18005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002892
VERSION     KCVT01002892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12033:18005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80417.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctacatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ctcgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01002893             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20298:2991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002893
VERSION     KCVT01002893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20298:2991"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80418.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 actggggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002894             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22725:17534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002894
VERSION     KCVT01002894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22725:17534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..317
                     /note="immunoglobulin light chain variable region"
     V_region        113..317
     V_segment       113..279
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <257..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80419.1"
                     /translation="CMQGLEFPITF"
     J_segment       282..317
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>320
                     /gene="IGKC"
BASE COUNT           70 a           84 c           89 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccaggcca
      121 gtctccacag ctcttgattt atgatgtttc caaccgggcc tctggagtcc cagacaggtt
      181 cagtggcagt gggtcagacg ctgatttcac actgagaatc agcagagtgg aggctgagga
      241 tgttggggtt tattactgca tgcaaggtct agagtttcca atcactttcg gccccgggac
      301 caaactggag atcaaacgag
//
LOCUS       KCVT01002895             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8923:17738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002895
VERSION     KCVT01002895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8923:17738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..427
                     /note="immunoglobulin light chain variable region"
     V_region        98..427
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80420.1"
                     /translation="CMQGLEFPITF"
     J_segment       402..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>439
                     /gene="IGKC"
BASE COUNT           95 a          123 c          116 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 gctcttggat actgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgatgtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagacg ctgatttcac actgcgaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcca atcactttcg gccccggtac
      421 caaactgaga tcaaacgag
//
LOCUS       KCVT01002896             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:25714:9557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002896
VERSION     KCVT01002896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25714:9557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80421.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          115 c          104 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggtttcc ctctcggttc agcggcagtg gttctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002897             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16877:10127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002897
VERSION     KCVT01002897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16877:10127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80422.1"
                     /translation="CQQYNSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          114 c          107 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gcagaaacca ggaaaagccc cgaaggcctt
      241 gatctattac gcatccattt tagaaagtgc ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctacagtct gacgattttg caacttatta
      361 ctgtcaacag tataacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002898             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13571:11527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002898
VERSION     KCVT01002898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13571:11527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80423.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          109 c          107 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgtatctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaccact tttttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattatgca aaccgtttgg aaagaggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagtagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01002899             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24237:13274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002899
VERSION     KCVT01002899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24237:13274"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80424.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          122 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactactc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002900             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4935:14006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002900
VERSION     KCVT01002900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4935:14006"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80425.1"
                     /translation="CQQYNSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          101 g          101 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gctagtcagg
      181 acattgctaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctaa
      241 tctattatgc aaaccgtttg ggaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc gtcagcagcc ttcaacctga cgattttgca acttattatt
      361 gtcaacagta taatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01002901             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8025:9134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002901
VERSION     KCVT01002901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8025:9134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80426.1"
                     /translation="CQQYNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagtataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01002902             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22249:5318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002902
VERSION     KCVT01002902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22249:5318"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..290
                     /note="immunoglobulin light chain variable region"
     V_region        16..290
     V_segment       16..253
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <230..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80427.1"
                     /translation="CQQYNSLPWTF"
     J_segment       254..290
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>293
                     /gene="IGKC"
BASE COUNT           81 a           71 c           74 g           67 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaccct cacttgccgg gcaagtcagg acattagcac
       61 ttttttaaat tggtatcaac agagaccggg gaaagcccct aagctcctga tctattatgc
      121 aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc actggatctg ggacagaatt
      181 cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact gtcaacagta
      241 taatagttta ccttggacgt tcggccaagg ggccagggtg gaaatcaaac gag
//
LOCUS       KCVT01002903             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10709:13612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002903
VERSION     KCVT01002903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10709:13612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80428.1"
                     /translation="CQQHDSYPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          121 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcac
      181 gacattagcg attctttagc ctggtatcag cacaaaccag gaaaagcccc gaagcccctg
      241 atctattacg catccaattt gaaaagtggg gtcccatcaa ggttcagggg cagtggatct
      301 gggacagaat tcactctcac catcaggagc ctgcagcctg aagattttgc aacctattat
      361 tgtcaacagc atgattctta cccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002904             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10954:17476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002904
VERSION     KCVT01002904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10954:17476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80429.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          115 c          118 g           99 t
ORIGIN      
        1 atggggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcaacag aaaccaggac aacctcctaa
      241 actcctgatt taccaagcaa tcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaacctgacg atggtgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01002905             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14818:21691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002905
VERSION     KCVT01002905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14818:21691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80430.1"
                     /translation="CLQYKSYPFTF"
     J_segment       381..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          104 a          114 c          100 g          103 t
ORIGIN      
        1 acatgggggc agacacagtc aggacacagc atggacatga gggcccccgc tcatctccta
       61 gggctcttgc tgctctggct cccaggtgcc aggtgtgaca tccagatgac tcagtctcca
      121 tcttccctgt ctgcatctgc aggagacact gtcaccatca cttgccgggc aagtcagggt
      181 attagtacct atttaaattg gtttcagcag aaaccaggga aagcccctaa gctcctgatc
      241 tatgctgcat cttatctgga aagtggggtc ccatcaaggt tcagcggcag tggatttggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattattgt
      361 ctacagtata aaagttatcc attcactttc ggccccggga ccaaactgga tatcaaacga
      421 g
//
LOCUS       KCVT01002906             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21820:5265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002906
VERSION     KCVT01002906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21820:5265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80431.1"
                     /translation="CMQPLEFPWSF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggtcgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002907             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18179:6323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002907
VERSION     KCVT01002907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18179:6323"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80432.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002908             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:23305:9378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002908
VERSION     KCVT01002908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23305:9378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80433.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agaacctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagaatt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002909             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10811:14776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002909
VERSION     KCVT01002909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10811:14776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    164..350
                     /note="immunoglobulin light chain variable region"
     V_region        164..350
     V_segment       164..313
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80434.1"
                     /translation="CQQDFDWPPTF"
     J_segment       316..350
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>353
                     /gene="IGKC"
BASE COUNT           81 a          102 c           94 g           76 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctcc tctatggtgc
      181 atccaccagg gcctccggca tcccaggcag gttcagtgcc agtgggtctg gaacagagtt
      241 tactctcacc atcagcagcc tggagcctga agatgttgga atttattact gtcagcagga
      301 ttttgactgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002910             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21586:8263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002910
VERSION     KCVT01002910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21586:8263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80435.1"
                     /translation="CIQSLEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          120 c          116 g          111 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc ttctcctgta ggtctagtca
      181 cagcctcttg gatagtgagg atggaaatat ccatttggat tggtatctgc agaagccagg
      241 ccagtctcca cacctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gtttagtggc agtgggtcag acactgattt cacactgaaa atcagcaggg tggaggctga
      361 ggatgttggg gtttactact gcatacaatc tcttgagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01002911             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6538:17374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002911
VERSION     KCVT01002911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6538:17374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80436.1"
                     /translation="CMQGLEFPPTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggcga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggtgat ggaaacacct atttggaatg gttcctccag aggccaggcc
      241 agtctccaca cctcttaatt tatggggctt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tccgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002912             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22481:12218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002912
VERSION     KCVT01002912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22481:12218"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80437.1"
                     /translation="CLQGDTSPFSF"
     J_segment       385..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          113 c          111 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gccaggacat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgatcta
      241 tgctgcatcc agtttggaga gtggggtccc atctaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gtctgaggat tttgcaactt attactgtct
      361 acagggtgat acttccccgt ttagtttcgg cggagggacc caggtggaga tcaaacgag
//
LOCUS       KCVT01002913             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19292:10374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002913
VERSION     KCVT01002913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19292:10374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80438.1"
                     /translation="CQQHADSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          119 c          111 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gggtattaac aactggttgg cctggtatca acagagacca gggaaagccc ctaaggtcct
      241 gatctatagg acatccaatt tggaaacagg ggtcccatca aggttcagtg gaaccggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg caacatatta
      361 ctgtcaacag catgctgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01002914             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20434:9782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002914
VERSION     KCVT01002914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20434:9782"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80439.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002915             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20337:19195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002915
VERSION     KCVT01002915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20337:19195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80440.1"
                     /translation="YMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactac atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002916             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13837:14250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002916
VERSION     KCVT01002916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13837:14250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80441.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctcatgctc tggctccctg tatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catgtcctgc aggtctagtc
      181 agagtctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagata
      301 ggttcagtgg cggtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 atgatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01002917             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7808:17174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002917
VERSION     KCVT01002917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7808:17174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..269
                     /note="immunoglobulin light chain variable region"
     V_region        6..269
     V_segment       6..229
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>245
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80442.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       239..269
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>276
                     /gene="IGKC"
BASE COUNT           73 a           66 c           72 g           65 t
ORIGIN      
        1 atgggatcac ttgtcgggca agtcaggaca ttggcaatta tttagcctgg tatcagcaga
       61 aaccagggaa agcccctaac ctcctgatct ataaggcgtc cagtttacaa agtggggtcc
      121 catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc
      181 agcctgaaga ttttgcagtt tattactgtc aacagcgtaa tagttacccg tacatgtgca
      241 gttttggccc ggggaccaaa gtggagatcc gacgag
//
LOCUS       KCVT01002918             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18057:14648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002918
VERSION     KCVT01002918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18057:14648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80443.1"
                     /translation="CQQYNSLPYIF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          103 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgttttt ttaaattggt atcagcagaa accggggaaa gcccctaaac ccctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat agtttaccgt acatttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002919             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10066:5084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002919
VERSION     KCVT01002919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10066:5084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80444.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaatcga g
//
LOCUS       KCVT01002920             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24438:18706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002920
VERSION     KCVT01002920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24438:18706"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80445.1"
                     /translation="CQQYNNLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          106 g          101 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctttaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agttttttga attggtatca gcagaaaccg gggaaagccc ctaacctcct
      241 gatctatttt gcaaaccgtt tggagagtgg ggtcccatca aggttcagcg gcagtgggtc
      301 tgggacaaga ttcactctca ccatcagcag cctccaacct gaagattttg caacttatta
      361 ctgtcaacag tataataatt taccgtacac ttttggccag gggaccaaag ttgagatcaa
      421 acgag
//
LOCUS       KCVT01002921             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:16944:6668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002921
VERSION     KCVT01002921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16944:6668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80446.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagt
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002922             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7731:11658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002922
VERSION     KCVT01002922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7731:11658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80447.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          119 c          104 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtac gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01002923             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4871:15512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002923
VERSION     KCVT01002923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4871:15512"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    158..347
                     /note="immunoglobulin light chain variable region"
     V_region        158..347
     V_segment       158..309
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <287..>319
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80448.1"
                     /translation="CMQALEFPYSF"
     J_segment       310..347
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>350
                     /gene="IGKC"
BASE COUNT           73 a           96 c           97 g           84 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcttgattt atgaggtttc
      181 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca cggatttcac
      241 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct
      301 agagtttccg tacagttttg gccaggggac cagagtggag atcaaacgag
//
LOCUS       KCVT01002924             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9881:8881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002924
VERSION     KCVT01002924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9881:8881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80449.1"
                     /translation="CQQHNFYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag cagaaaccag ggagagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac cgtcagcagc ctgcagcctg aagattttgc aatttattac
      361 tgtcaacagc ataattttta ccctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002925             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7291:7260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002925
VERSION     KCVT01002925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7291:7260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80450.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          123 c          118 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagcg tagcctggta ccagcagaaa cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01002926             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9145:20741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002926
VERSION     KCVT01002926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9145:20741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80451.1"
                     /translation="CLQYKTYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          108 a          114 c          101 g           96 t
ORIGIN      
        1 acatgggcag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcaaatgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 aagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa acttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01002927             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17323:22052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002927
VERSION     KCVT01002927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17323:22052"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80452.1"
                     /translation="CLQGYNTPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          112 c          112 g           96 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccagt tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacctgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gtgtccagtt tggaaggtgg ggtcccatca agattcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagatcttg cgacttatta
      361 ctgtctacag ggttataata ccccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002928             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:19662:12555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002928
VERSION     KCVT01002928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19662:12555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    49..370
                     /note="immunoglobulin light chain variable region"
     V_region        49..370
     V_segment       49..323
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <310..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80453.1"
                     /translation="CQQHNNYSPTF"
     J_segment       336..370
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>373
                     /gene="IGKC"
BASE COUNT           98 a          102 c           92 g           81 t
ORIGIN      
        1 acatgggggg agtcagaacc actcagctgg ctcccaggtg ccagatgtga catccagatg
       61 acccagtctc caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg
      121 gcaagtcagg gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg
      181 aagcccctga tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc
      241 agtggatctg ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca
      301 acttattact gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg
      361 gagatcaaac gag
//
LOCUS       KCVT01002929             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:25447:9439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002929
VERSION     KCVT01002929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25447:9439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80454.1"
                     /translation="CQQYNNDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          113 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ccaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagaa gttatttagc gtggtatcag atgagaccag ggaaagcccc gagggcctta
      241 atctattacg cgaccatttt ggaaggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcggcagc ctgcagcctg aggattttgc aacttatttc
      361 tgtcaacagt ataacaatga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002930             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19428:12371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002930
VERSION     KCVT01002930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19428:12371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..429
                     /note="immunoglobulin light chain variable region"
     V_region        108..429
     V_segment       108..391
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80455.1"
                     /translation="CLQYRSYPYNF"
     J_segment       392..429
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          111 a          113 c          108 g          100 t
ORIGIN      
        1 acatggggtc ttgcaggagt cagacacagt caggacacag catggacatg agggcccccg
       61 ctcatctcct agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga
      121 ctcagtctcc atcttccctg tctgcatctg taggagacac tgtcaccatc acttgccggg
      181 caagtcagga tattagcagt tatttaaatt ggtttcagaa gaaaccaggg aaagccccta
      241 agctcctgat ccaagctgca tccagtttgg aaagtggggt cccatcaagg ttcagcggca
      301 gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa
      361 cttattactg tctacagtat agaagttacc cgtacaattt tggccagggg accaaagtgg
      421 agatcaaacg ag
//
LOCUS       KCVT01002931             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12860:13874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002931
VERSION     KCVT01002931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12860:13874"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80456.1"
                     /translation="CQQYDNDPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          117 c          108 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacaatga cccgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01002932             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22750:3238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002932
VERSION     KCVT01002932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22750:3238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80457.1"
                     /translation="CQQYNSDPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          113 c          115 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag gtgacccagt
      121 ctccgtcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcgttag aagttattta gcgtggtatc agctgagacc agggaaagcc ccgaaggcct
      241 taatctatta cgcgaccatt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaggatttt gcaacttatt
      361 tctgtcaaca gtataacagt gacccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01002933             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8297:10726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002933
VERSION     KCVT01002933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8297:10726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80458.1"
                     /translation="CQQDFDWPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          126 c          115 g           88 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ctccagcaca
       61 gcttctcttc ctcctgctac tctggatccc agataccacc ggagaagttg tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg ggaaagagcc accctctcct gcagggccag
      181 tcagagtgtt ggcaacacct taacctggta ccagcacaaa cctgggcagg ctcccaagct
      241 cctcctctat ggtgcatcca ccagggcctc cggcatccca ggcaggttca gtgccagtgg
      301 gtctggaaca gagtttactc tcaccatcag cagcctggag cctgaagatg ttggaattta
      361 ttactgtcag caggattttg actggcctcc gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01002934             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16657:15340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002934
VERSION     KCVT01002934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16657:15340"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80459.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctcctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002935             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19489:18901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002935
VERSION     KCVT01002935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19489:18901"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80460.1"
                     /translation="CQQHNNYSPTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccac
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttagcaatga tttagcctgg tatcagctga aaccagggaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacaacataa taattactct cccactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01002936             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15013:20078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002936
VERSION     KCVT01002936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15013:20078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80461.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          122 c          118 g           91 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagac tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtccagtca aagccttgta
      181 cacatcaatg gacacacata cttgagttgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 gggacaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattcctgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01002937             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17900:13280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002937
VERSION     KCVT01002937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17900:13280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80462.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc cgttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002938             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9564:8631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002938
VERSION     KCVT01002938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9564:8631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..390
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80463.1"
                     /translation="CQQDFDWPPTF"
     J_segment       393..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          126 c          117 g           88 t
ORIGIN      
        1 acatgggggg gggaggaact gctcagttag gacccagagg gaaccatgga agctccagca
       61 cagcttctct tcctcctgct actctggatc ccagatacca ccggagaagt tgtgatgacg
      121 cagtctccag ccaccctgtc tttgtctcca ggggaaagag ccaccctctc ctgcagggcc
      181 agtcagagtg ttggcaacac cttaacctgg taccagcaca aacctgggca ggctcccaag
      241 ctcctcctct atggtgcatc caccagggcc tccggcatcc caggcaggtt cagtgccagt
      301 gggtctggaa cagagtttac tctcaccatc agcagcctgg agcctgaaga tgttggaatt
      361 tattactgtc agcaggattt tgactggcct ccgacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01002939             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13794:13638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002939
VERSION     KCVT01002939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13794:13638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80464.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagtagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002940             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22009:9371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002940
VERSION     KCVT01002940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22009:9371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80465.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct ccttctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01002941             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12086:16789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002941
VERSION     KCVT01002941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12086:16789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80466.1"
                     /translation="CQKYISSPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          129 c          105 g           92 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caacttatat tgactcagtc
      121 tccagccacc ctgtctctgt ctccagggga aagagccacc ctctcttgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccaggctcct
      241 cctctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtatatta
      361 ctgtcagaaa tatattagct ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01002942             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:5085:4096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002942
VERSION     KCVT01002942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5085:4096"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80467.1"
                     /translation="CQQHNGYPPTF"
     J_segment       399..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          112 a          121 c          108 g           95 t
ORIGIN      
        1 acatgggaca cttcatgtag gagtcagaac cactcaggac acagcatgga catgagggtc
       61 cccgctcagc tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag
      121 atgacccagt ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt
      181 cgggcaagtc agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc
      241 ccgaagcccc tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc
      301 ggcagtggat ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt
      361 gcaacttatt attgtcaaca gcataatgga tatcctccga cgttcggcca agggaccagg
      421 gtggaaatca aacgag
//
LOCUS       KCVT01002943             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:11915:4581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002943
VERSION     KCVT01002943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11915:4581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80468.1"
                     /translation="CMQALDFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          121 g          104 t
ORIGIN      
        1 atggggactg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tgcagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgcg
      361 gatgttgggg tttattactg catgcaagct ctagactttc ccctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002944             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7728:16610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002944
VERSION     KCVT01002944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7728:16610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80469.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          126 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagt cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002945             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23154:17191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002945
VERSION     KCVT01002945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23154:17191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80470.1"
                     /translation="CQQVYSSPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          114 c          107 g          104 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccagatg acccagtctc
      121 catctgcctt gtctgcatct gtgggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag ttatttagcg tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatgctgt atccagattg caaagtgggg ttccctctcg gttcagcggc agtggaactg
      301 ggacagattt cactctcagc atcagcagcc tacagcctga agattctgcc ggttattact
      361 gtcaacaggt ttatagtagt ccattcactt tcggccccgg gaccaaactg gctatcaaac
      421 gag
//
LOCUS       KCVT01002946             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18645:1940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002946
VERSION     KCVT01002946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18645:1940"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80471.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01002947             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16741:3805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002947
VERSION     KCVT01002947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16741:3805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..276
                     /note="immunoglobulin light chain variable region"
     V_region        127..276
     V_segment       127..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80472.1"
                     /translation="CMQALEFPLTF"
     J_segment       240..276
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           62 a           72 c           78 g           67 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc agacaggttc agtggcagtg ggtcagccac tgatttcaaa ctgaacatca
      181 gcagagtgga ggctgaggat gttggggttt attactgcat gcaagctcta gagtttcctc
      241 tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002948             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16810:4507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002948
VERSION     KCVT01002948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16810:4507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80473.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          116 c          117 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtttttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgtatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 attgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002949             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20593:8370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002949
VERSION     KCVT01002949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20593:8370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80474.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          112 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccgtc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcgt
      181 tagaagttat ttagcgtggt atcagctgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acagtataac agtgacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002950             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14347:13506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002950
VERSION     KCVT01002950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14347:13506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80475.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt tcaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002951             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18073:20168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002951
VERSION     KCVT01002951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18073:20168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..405
                     /note="immunoglobulin light chain variable region"
     V_region        84..405
     V_segment       84..368
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80476.1"
                     /translation="CQQNSNWPLTF"
     J_segment       369..405
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT           96 a          119 c          111 g           82 t
ORIGIN      
        1 acatggggga cccagaggga accatggaag ccccagcaca gcttctcttc ctcctgctgc
       61 tctggctccc agataccacc ggagaaatag tgatgacgca gtctccagcc accctgtctt
      121 tgtctccagg agaaagagcc accctctcct gcagggccag tcagagtgtc agcagcagct
      181 tagcctggta ccagcagaaa cctgggcagg ctcccaggct cctcatctat ggtgcatcca
      241 acagggccac tggcatccca gacaggttca gtggcagtgg gtctgggaca gagttcactc
      301 tcaccatcag cagcctggag cctgaagatg ttgcagttta ttattgtcag cagaatagta
      361 actggcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002952             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23123:10955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002952
VERSION     KCVT01002952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23123:10955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80477.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01002953             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17663:11502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002953
VERSION     KCVT01002953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17663:11502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..422
                     /note="immunoglobulin light chain variable region"
     V_region        103..422
     V_segment       103..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80478.1"
                     /translation="CLQGYSPPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          118 c          108 g           98 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gccatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaaactc ctgagcgcct
      241 gatctatgct gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg taggttattt
      361 ctgtctacag ggttacagtc ccccattcac tttcggcccc gggaccaaac tggatttcaa
      421 acgag
//
LOCUS       KCVT01002954             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20630:14207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002954
VERSION     KCVT01002954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20630:14207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..343
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80479.1"
                     /translation="CQQYNSEPRTF"
     J_segment       351..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           92 a          107 c          101 g           88 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcagggcatt cgcagttatt tagcgtggta tcagcagaaa
      181 ctagggaaac ccccgaagcc cttgatctat tacgcgtcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcaa cagtataaca gtgagccgcg cactttcggt
      361 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01002955             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:23718:6456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002955
VERSION     KCVT01002955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23718:6456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80480.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacaaaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002956             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20359:14448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002956
VERSION     KCVT01002956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20359:14448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..366
                     /note="immunoglobulin light chain variable region"
     V_region        87..366
     V_segment       87..326
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80481.1"
                     /translation="CQRYSYSTWTF"
     J_segment       329..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           87 a          101 c          106 g           75 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gggaaagagc caccctctcc tgcagggcca
      121 gtcagagtgt tggcagcagc ttggtttggt accagcagaa acctgggcag gcccccaggc
      181 tcctcatcta tggtgcatcc agcagggcca ctggcatccc agacaggttc agtggcagtg
      241 ggtctgggac agagttcact ctcaccatca gcagcctgga gcctgaagat tttgcagtat
      301 attactgtca gaggtatagt tactccacgt ggacgttcgg ccaagggacc aaggtggaaa
      361 tcaaacgag
//
LOCUS       KCVT01002957             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:3074:15789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002957
VERSION     KCVT01002957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:3074:15789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80482.1"
                     /translation="CMQALQFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttcga atggtaccta cagaggccag
      241 gccagtctcc acaccttttg atttatgagt tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcactctgaa tatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctacaatt tccgtggacg ttcggccaag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01002958             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12463:4848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002958
VERSION     KCVT01002958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12463:4848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80483.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           95 a          127 c          110 g           94 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtatc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01002959             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16708:5580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002959
VERSION     KCVT01002959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16708:5580"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..377
                     /note="immunoglobulin light chain variable region"
     V_region        106..377
     V_segment       106..325
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <317..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80484.1"
                     /translation="CLQGDTAPFTF"
     J_segment       342..377
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>380
                     /gene="IGKC"
BASE COUNT           94 a           99 c          102 g           85 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagag tcaccatcac
      121 ttgccgggca agtcagggca ttaacgatta tttaagttgg tatcagcaga aaccaggaaa
      181 acctcctaag cgcctaatct atgctgcatc tagtttggaa agtggggtcc catcaaggtt
      241 cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc agcctgaaga
      301 ttttgcagtt tattactgtc tacagggtga tactgccccg ttcactttcg gcggagggac
      361 caaggtggag atcaaacgag
//
LOCUS       KCVT01002960             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18532:13351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002960
VERSION     KCVT01002960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18532:13351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80485.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaaac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002961             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14097:5940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002961
VERSION     KCVT01002961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14097:5940"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80486.1"
                     /translation="CQQVYSYPCSF"
     J_segment       382..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          108 c          108 g          103 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatgataat ttagcgtggt ttcagcagaa agcagggaaa gcccctaaac tcctgatcta
      241 tactgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcagttt attactgtca
      361 acaggtttat agttacccgt gcagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01002962             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24120:9925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002962
VERSION     KCVT01002962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24120:9925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..390
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80487.1"
                     /translation="CQQGNSNPLTF"
     J_segment       391..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          108 a          111 c          113 g           98 t
ORIGIN      
        1 acatggggga ggaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctgg ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgtcc
      121 cagtttccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca
      181 agtcaggcca tttacagtta tttaaattgg tatcagcaga aaccggggaa agcccctaaa
      241 ctcctgatat attatgcaaa tagtttggca agtggggtcc catcacggtt cagcggcagt
      301 ggatctggga cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact
      361 tattactgtc aacagggtaa tagtaatcct ctcactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01002963             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15057:3878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002963
VERSION     KCVT01002963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15057:3878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80488.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          116 c          107 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accaggaaaa gccccgaggc ccttgatcca
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002964             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13576:13629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002964
VERSION     KCVT01002964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13576:13629"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80489.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          119 c          106 g           91 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg tgggagacac agtcaccatc acttgtcggg caagtcaggt
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01002965             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20741:8299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002965
VERSION     KCVT01002965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20741:8299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80490.1"
                     /translation="CQQYDSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          114 c          113 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc ggagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01002966             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15110:14863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002966
VERSION     KCVT01002966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15110:14863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80491.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002967             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:20201:8209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002967
VERSION     KCVT01002967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20201:8209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80492.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          119 c          126 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcaccc tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac gtagtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagtc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgggga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002968             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12206:12702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002968
VERSION     KCVT01002968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12206:12702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80493.1"
                     /translation="CQQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          110 c          106 g          100 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cacatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg tgggagacag agtcaccatc acttgccggg caagtcggga
      181 cattggcaat tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctaat
      241 cttttatgca aaccgtttgg aaaatggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacggaattc actctcacca tcagcagcct gcaacctgag gattttgcaa tttattattg
      361 tcaacaatat aatagtttac cgtacacttt tggccagggg accaaagtgg acatcaaacg
      421 ag
//
LOCUS       KCVT01002969             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14182:6895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002969
VERSION     KCVT01002969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14182:6895"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80494.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          121 c          115 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01002970             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11908:15699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002970
VERSION     KCVT01002970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11908:15699"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80495.1"
                     /translation="CQQGNGLPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          109 c          107 g          103 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcag ttgccgggca agtcaggcca
      181 ttagcagtta tttattttgg tatcagcaga agccggggaa agcccctaaa cttctgattt
      241 ataaggcaaa tcttttggaa gatggggtcc catctaggtt cagcggcagt ggatctggga
      301 cagagttcac tctcactatc agcagcctgc aacctgtaga ttttgcaact tattactgtc
      361 aacaaggtaa tggtttacca ttcactttcg gccccgggac caaagtggat atcaaacgag
//
LOCUS       KCVT01002971             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11025:22946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002971
VERSION     KCVT01002971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11025:22946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80496.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          121 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat tcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggtgagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctt tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002972             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:8482:2794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002972
VERSION     KCVT01002972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8482:2794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80497.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcagc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002973             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13873:20924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002973
VERSION     KCVT01002973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13873:20924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..426
                     /note="immunoglobulin light chain variable region"
     V_region        93..426
     V_segment       93..388
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80498.1"
                     /translation="CLQSKNSPWSF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           96 a          116 c          117 g          100 t
ORIGIN      
        1 atggggagca gcctctagtt cagctctcag aaatggggtc ctgggctcct ttcctgtgga
       61 tcctcctgct ctgtgctcca ggctgcactg gggacattgt gctgacccag tctccagcct
      121 ctttggccgt gtctccaggg cagagggcca ccttcacctg cagagccagt gggagtgtca
      181 gtgcctttgg aataagcctc attcactggt atcagcagaa accaggacaa cctcctaaac
      241 tcctgattta tcaagcaagc aataaggaga ctggggtccc agccaggttc agcggcagtg
      301 ggtctgggac cgatttcacc ctcacaatta atcctgtgga acctgacgat gctgcagatt
      361 attactgtct gcagagtaag aattctccgt ggtcgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01002974             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17759:16735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002974
VERSION     KCVT01002974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17759:16735"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..395
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80499.1"
                     /translation="CQQNSNRPYTF"
     J_segment       396..433
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          102 a          122 c          122 g           90 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagtagttta gcctggtacc agcagagacc tgggcaggct
      241 cccaggctcc tcatctatgg tgtatccagc agggccactg gcatcccaga cagattcagt
      301 ggcagtgggt ctgggacaga gttcactctc accatcagca gcctggagcc cgaagatgtt
      361 gcagtttatt tttgtcagca gaatagtaat cggccgtaca cttttggcca ggggaccaaa
      421 gtggagatca aacgag
//
LOCUS       KCVT01002975             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19013:9698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002975
VERSION     KCVT01002975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19013:9698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80500.1"
                     /translation="CQHSYDTPYTF"
     J_segment       386..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtgc
      181 gagcgttagc gactatttac attggtatca gcagaaacca gggaaagccc ctgagctcct
      241 gatctatgct acatccactt tgcaaagtgg ggtaccatta cggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agttatgata ccccctacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01002976             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9458:7023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002976
VERSION     KCVT01002976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9458:7023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80501.1"
                     /translation="CQQYDSDTLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac acgctcactt tcggtggagg gaccaatgta gagatcaaac
      421 gag
//
LOCUS       KCVT01002977             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18936:19505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002977
VERSION     KCVT01002977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18936:19505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80502.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          121 g          104 t
ORIGIN      
        1 aacatggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01002978             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19681:15680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002978
VERSION     KCVT01002978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19681:15680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80503.1"
                     /translation="CQQGNSIPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          114 c          107 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagcagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattatgca gacagtttgt caagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctaaa gattttgcaa cctattactg
      361 tcaacagggt aatagtattc cattcacttt cggccccggg accaaagtgg atatcaaacg
      421 ag
//
LOCUS       KCVT01002979             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9859:9634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002979
VERSION     KCVT01002979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9859:9634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80504.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002980             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:8391:11166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002980
VERSION     KCVT01002980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8391:11166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80505.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gagtctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002981             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18687:4055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002981
VERSION     KCVT01002981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18687:4055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80506.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagccc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01002982             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22668:6642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002982
VERSION     KCVT01002982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22668:6642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80507.1"
                     /translation="CMQNTEDPTF"
     J_segment       399..429
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>431
                     /gene="IGKC"
BASE COUNT           99 a          118 c          109 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctgggt ccagtgggga tattgtgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga aacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacgtct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaagatg
      361 ttggtgttta ttattgcatg caaaatacag aagatcccac tttcggcccc gggaccaaac
      421 tggatatcat a
//
LOCUS       KCVT01002983             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16106:20539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002983
VERSION     KCVT01002983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16106:20539"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80508.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgc gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01002984             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:11299:8204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002984
VERSION     KCVT01002984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11299:8204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80509.1"
                     /translation="CMQYRHIPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          114 g          110 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagact
      121 ccattctccc tgtccgttag ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttga atagtgaaga cggaaacacc tatttggatt ggtacctgca gaggccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01002985             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20801:21197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002985
VERSION     KCVT01002985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20801:21197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80510.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          127 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 ccctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002986             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22808:20415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002986
VERSION     KCVT01002986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22808:20415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..296
                     /note="immunoglobulin light chain variable region"
     V_region        86..296
     V_segment       86..244
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <236..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80511.1"
                     /translation="CLQQCNNPLTF"
     J_segment       259..296
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>299
                     /gene="IGKC"
BASE COUNT           76 a           83 c           78 g           62 t
ORIGIN      
        1 acatggggaa gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccagaa accaggaaaa gctcctaagc gcctgatcta
      121 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      181 agatttcact ctcaccagca gcagcctgca gcctgaagat tttgcaactc attactgtct
      241 acagcaatgt aataacccgc tcactttcgc tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01002987             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11879:14885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002987
VERSION     KCVT01002987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11879:14885"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..278
                     /note="immunoglobulin light chain variable region"
     V_region        10..278
     V_segment       10..236
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80512.1"
                     /translation="CQQYDSDSLTF"
     J_segment       241..278
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>281
                     /gene="IGKC"
BASE COUNT           74 a           68 c           75 g           64 t
ORIGIN      
        1 acatgggaga gtcaccatca cttgtcgggc gactcaggac attcgcagtt atttagcgtg
       61 gtatcagcag aaaccaggga aagccccgaa gcccttgatc tattacgcgt ccactttgga
      121 aagtggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat
      181 cagcagcctg cagcctgaag attttgcaac ttattactgt caacagtatg acagtgattc
      241 gctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002988             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5882:19969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002988
VERSION     KCVT01002988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5882:19969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80513.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          108 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggag tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaca atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccaaagtg gagattaaac gag
//
LOCUS       KCVT01002989             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10831:7951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002989
VERSION     KCVT01002989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10831:7951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80514.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          121 c          119 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atattggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01002990             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11887:10475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002990
VERSION     KCVT01002990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11887:10475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..412
                     /note="immunoglobulin light chain variable region"
     V_region        94..412
     V_segment       94..377
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80515.1"
                     /translation="CQQVLTNPAF"
     J_segment       380..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>415
                     /gene="IGKC"
BASE COUNT          101 a          112 c          104 g           98 t
ORIGIN      
        1 acatgggagt ctcagtcagg acacagcatg gacatgaggg tccctgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgatatcc aggtgaccca gtctccatct
      121 gccttgtctg catctgtagg agacagagtc accatctctt gccgggcaag tcagaacatt
      181 tataggaatt tagcgtggta tcagcagaaa ccagggaaag cccctaaact cctgatctat
      241 gctgcatcca gattgcaaag tgggtttccc tctcggttca gcggcagtgg atctgggaca
      301 gatttcactc tcaccatcag caacctacag cctgaagatt ctgcaattta ttactgtcaa
      361 caggttctta ctaacccggc gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01002991             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24079:4306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002991
VERSION     KCVT01002991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24079:4306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80516.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           94 a          123 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggggtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01002992             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8601:13054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002992
VERSION     KCVT01002992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8601:13054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    71..392
                     /note="immunoglobulin light chain variable region"
     V_region        71..392
     V_segment       71..354
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80517.1"
                     /translation="CLQYNSSPLTF"
     J_segment       355..392
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>395
                     /gene="IGKC"
BASE COUNT           93 a          110 c          102 g           90 t
ORIGIN      
        1 acatggggac atgagggtcc ctgctcagtt cctggggctc ctgctgctct ggctcccagg
       61 tgccagatgt gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga
      121 cacagtcacc atcacttgcc gggcgagtca gactattagc agctggttag actggtatca
      181 gcagaaacca gggaaagccc ctaacctcct gatctttaag gcatccagtt tgcaaagtgg
      241 ggtcccctca aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag
      301 cctgcagcct gaagattttg caacttatta ttgtctacag tacaatagta gcccgctcac
      361 tttcggcgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01002993             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26017:9359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002993
VERSION     KCVT01002993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26017:9359"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80518.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caagttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01002994             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12114:16471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002994
VERSION     KCVT01002994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12114:16471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80519.1"
                     /translation="CMQALEFPFTF"
     J_segment       275..312
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           71 a           84 c           82 g           78 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattttaatg acccagactc
      121 cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga taatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctagagt ttccattcac cttcggcccc gggaccaaac
      301 tggatatcaa acgag
//
LOCUS       KCVT01002995             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24824:9588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002995
VERSION     KCVT01002995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24824:9588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80520.1"
                     /translation="CHQGNSFPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          113 a          107 c          105 g           99 t
ORIGIN      
        1 acatggggat gagcaaaact gacaagtcaa ggcaggaaga tgttgtctcc atcacaactc
       61 attgggtttc tgctgctctg ggttccagcc tccaagggtg aaattgtgct gactcagtct
      121 ccagtctttc ggtctgtgac tctaaaggag aaagtcacca tcacctgcca ggccagtcag
      181 aacattggta ataagctaca ctggtaccag cagaaaccgg atcagtctcc aaaactcctc
      241 atcaagtatg cttcccagtc catctcaggg gtcccctcaa ggttcagtgg cagtggatct
      301 gggacagatt tcacccttac catcaatagc ctggaagctg aagatgctgc gacgtattac
      361 tgtcaccagg gtaatagttt tccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01002996             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15362:4718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002996
VERSION     KCVT01002996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15362:4718"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80521.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgtgat gacccagact
      121 ccgctctccc tgcccgtcat ccttggagag ccggcctccc tatcctgcac gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01002997             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18208:18325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002997
VERSION     KCVT01002997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18208:18325"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80522.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01002998             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22600:12363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002998
VERSION     KCVT01002998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22600:12363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..429
                     /note="immunoglobulin light chain variable region"
     V_region        113..429
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80523.1"
                     /translation="CQQDYSWPLTF"
     J_segment       398..429
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>437
                     /gene="IGKC"
BASE COUNT          101 a          122 c          123 g           91 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagtagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaacgagcca ccctctcctg
      181 cagggccagt cagagtattg gcagcacctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccaagctc ctcatctatg gtgcatccag cagggccacc gacatcccag acaggttcag
      301 tggcagtggg tctggaacag aatttactct caccatcagc agcctggagt ctgtagatgt
      361 tggagtttat tactgtcagc aggattatag ctggcctctc actttcggcg gagggaccaa
      421 ggtggagatg agacgag
//
LOCUS       KCVT01002999             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10760:11920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01002999
VERSION     KCVT01002999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10760:11920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80524.1"
                     /translation="CMQGLEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          122 c          116 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gaccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgtaggggt ttattactgc atgcaaggtc tagaatttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003000             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20286:18019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003000
VERSION     KCVT01003000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20286:18019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..431
                     /note="immunoglobulin light chain variable region"
     V_region        99..431
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80525.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          122 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagta ccagacaggt
      301 tcagtggcag tgggtcagac actgctttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccagggtgga acccaaacga g
//
LOCUS       KCVT01003001             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8855:20122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003001
VERSION     KCVT01003001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8855:20122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..373
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80526.1"
                     /translation="CQQHDNSPPTF"
     J_segment       376..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          102 a          113 c          108 g           90 t
ORIGIN      
        1 acatggggag acagggcaca gcatggacac gagggtcccc gctcagctcc tggggctcct
       61 gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc cttcctccct
      121 gtctgcatct ataggcgaca gagtcaccat cacttgcaga gccagtcagg gtattagcga
      181 ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaactcctga tctatagggc
      241 atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg ggacagattt
      301 cactctcacc atcagcagcc tgcaggctga agatttcgca acatatttct gtcaacagca
      361 tgataattcc cctcccactt tcggtggagg gactaaggtg gagatcaaac gag
//
LOCUS       KCVT01003002             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13447:11257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003002
VERSION     KCVT01003002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13447:11257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80527.1"
                     /translation="CQQVYSNPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          115 c          106 g          104 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtct
      121 ccatctgcct tgtctgcatc tgtgggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata gttatttagc gtggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgcta catccagatt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagtctg aagattctgc agcttattac
      361 tgtcaacagg tttatagtaa cccgttcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003003             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11614:4262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003003
VERSION     KCVT01003003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11614:4262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80528.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          116 c          111 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgaaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacatacgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003004             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:9888:6997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003004
VERSION     KCVT01003004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9888:6997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..392
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80529.1"
                     /translation="CLQSKNSPWSF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          117 c          119 g          100 t
ORIGIN      
        1 acatgggggg agcagcctct agttcagctc tcagaaatgg ggtcctgggc tcctttcctg
       61 tggatcctcc tgctctgtgc tccaggctgc actggggaca ttgtgctgac ccagtctcca
      121 gcctctttgg ccgtgtctcc agggcagagg gccaccttca cctgcagagc cagtgggagt
      181 gtcagtgcct ttggaataag cctcattcac tggtatcagc agaaaccagg acaacctcct
      241 aaactcctga tttatcaagc aagcaataag gagactgggg tcccagccag gttcagcggc
      301 agtgggtctg ggaccgattt caccctcaca attaatcctg tggaacctga cgatgctgca
      361 gattattact gtctgcagag taagaattct ccgtggtcgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01003005             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20432:13395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003005
VERSION     KCVT01003005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20432:13395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80530.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcctgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003006             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14846:11645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003006
VERSION     KCVT01003006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14846:11645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80531.1"
                     /translation="CLQFKTFPYSF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT           96 a          116 c          104 g          101 t
ORIGIN      
        1 atggggagac acagtcagga cacagcatgg acatgagggc ccccgctcat ctcctagggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgactcag tctccatctt
      121 ccctgtctgc atctgtagga gacactgtca ccatctcttg ccgggcaagt cagggtatta
      181 gcagttcttt aagttggttt cagcagaaac cagggaaagc ccctaagctc ctcatctatg
      241 ctgcatccac tttggccggt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 acttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtctac
      361 agtttaaaac tttcccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01003007             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23042:6570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003007
VERSION     KCVT01003007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23042:6570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80532.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          123 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct acccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaagtgga tatcaaacga g
//
LOCUS       KCVT01003008             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15646:14645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003008
VERSION     KCVT01003008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15646:14645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80533.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          104 a          123 c          115 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcaaaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acagattcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01003009             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13310:9628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003009
VERSION     KCVT01003009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13310:9628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80534.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccaggcac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003010             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13341:18017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003010
VERSION     KCVT01003010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13341:18017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80535.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          114 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcctgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003011             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6228:10955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003011
VERSION     KCVT01003011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6228:10955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80536.1"
                     /translation="CLQGYITPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          113 c          110 g           99 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac ttccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tttttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat
      241 ttatgctgca tccagtttgc aaagtggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcgg cttattactg
      361 tctacagggt tatattaccc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003012             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8024:5677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003012
VERSION     KCVT01003012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8024:5677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80537.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc actcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003013             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14828:9681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003013
VERSION     KCVT01003013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14828:9681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80538.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          109 c          109 g           95 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtta ttatttaaat tggtatcaac agaaaccggg gaaagcccct aaggtcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca agttattact
      361 gtcaacaata taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003014             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8575:11380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003014
VERSION     KCVT01003014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8575:11380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..275
                     /note="immunoglobulin light chain variable region"
     V_region        6..275
     V_segment       6..237
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80539.1"
                     /translation="CMQALEFPWTF"
     J_segment       238..275
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           70 a           58 c           84 g           66 t
ORIGIN      
        1 acatggggct agtcagagtc tcttggatag tgaggatgga aacacctatt tggaatggta
       61 cctgcagaag ccaggccagt ctccacagct cttgatttat gaggtttcca accgggcctc
      121 tggagtccca gacaggttca gtggcggtgg gtcagacact gatttcacac tgaaaatcag
      181 cagagtggag gctgatgatg ttggggttta ttactgcatg caagctctag agtttccgtg
      241 gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003015             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18671:19706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003015
VERSION     KCVT01003015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18671:19706"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80540.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          115 c          102 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aactatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01003016             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:20740:10407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003016
VERSION     KCVT01003016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20740:10407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80541.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tgactcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003017             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11612:22389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003017
VERSION     KCVT01003017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11612:22389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80542.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          114 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgccctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003018             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:23535:10471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003018
VERSION     KCVT01003018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23535:10471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80543.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01003019             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22631:6032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003019
VERSION     KCVT01003019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22631:6032"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80544.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgtgat gacccagact
      121 ccactctccc tggccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacgcc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 atcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003020             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14215:17377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003020
VERSION     KCVT01003020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14215:17377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80545.1"
                     /translation="CHQYNNLPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          113 c          103 g           96 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaacattta tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 attatgcaaa tcgtttggaa actggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc aacagcctgc aacccgaaga ttttgcaact tattactgtc
      361 accagtataa taatttacca ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003021             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25226:9961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003021
VERSION     KCVT01003021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25226:9961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80546.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctacatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01003022             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12191:18311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003022
VERSION     KCVT01003022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12191:18311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80547.1"
                     /translation="CMQALEFPWTF"
     J_segment       348..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           86 a           98 c          112 g           91 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccagt ctccctgccc gtcaccctgg gagagccggc ctccatctcc tgccggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggcac ctgcagaggc
      181 caggccagtc tccacagctc ttgatttatg aggtttccta tcgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tggtatttat tactgcatgc aagctctaga gtttccttgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01003023             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:22581:12171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003023
VERSION     KCVT01003023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:22581:12171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80548.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          127 c          110 g           88 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga gagagccacc ctctcctgca gagccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctttggt acatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tcgaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003024             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13094:12323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003024
VERSION     KCVT01003024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13094:12323"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80549.1"
                     /translation="CQQHADSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          120 c          107 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagccac
      181 gatataaata attggttggc ctggtatcaa cagaaaccag gaaaagcccc taacctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgctgattc ccctcggacg ttcggccaag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003025             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6257:12328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003025
VERSION     KCVT01003025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6257:12328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80550.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003026             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6538:13897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003026
VERSION     KCVT01003026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6538:13897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80551.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aactag
//
LOCUS       KCVT01003027             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14845:15841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003027
VERSION     KCVT01003027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14845:15841"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80552.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgttct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003028             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20404:17288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003028
VERSION     KCVT01003028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20404:17288"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80553.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          117 c          103 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aagactttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003029             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14176:5138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003029
VERSION     KCVT01003029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14176:5138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80554.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          122 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003030             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15056:21998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003030
VERSION     KCVT01003030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15056:21998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80555.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct actcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003031             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21287:13530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003031
VERSION     KCVT01003031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21287:13530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..348
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80556.1"
                     /translation="CQQHDDSPRTF"
     J_segment       350..385
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           99 a          109 c           97 g           83 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctgggg ctcctgttgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gcacagccag ccacgatata aataactggt tggcctggta tcaacagaaa
      181 ccaggaaaag cccctaagct cctgatctat agggcatcca atttggaaac aggggtccca
      241 tcgaggttca gtggaagtgg atctgggaca gatttcactc tcagcatcag cagcctgcag
      301 cctgaagatt tcgcaacata ttactgtcaa cagcatgatg attcccctcg gacgttcggc
      361 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003032             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19952:10974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003032
VERSION     KCVT01003032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19952:10974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80557.1"
                     /translation="CMHTLEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          116 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcgt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggacacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca ggtcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat tagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcatactc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003033             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8891:4428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003033
VERSION     KCVT01003033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8891:4428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80558.1"
                     /translation="CMQGTQLLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          117 c          114 g           96 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca accggcctcc atctcctgca ggtctagtca aagccttcta
      181 cacactgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg agactgagga tgttggagtt
      361 tattactgca tgcaaggtac acagcttctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01003034             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18500:6788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003034
VERSION     KCVT01003034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18500:6788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80559.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003035             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18774:4152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003035
VERSION     KCVT01003035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18774:4152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80560.1"
                     /translation="CMQALEFPLTF"
     J_segment       276..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           68 a           82 c           93 g           72 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cacagctctt gatttatgag gtttccaagc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc aggcactgat ttcacactga aaatcagcag agtggaggct ggggatgttg
      241 gggtttatca ctgcatgcaa gctctagagt ttcctctcac tttcggcgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01003036             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14234:23956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003036
VERSION     KCVT01003036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14234:23956"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..329
                     /note="immunoglobulin light chain variable region"
     V_region        8..329
     V_segment       8..291
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80561.1"
                     /translation="CQQYNSLPLTF"
     J_segment       292..329
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>332
                     /gene="IGKC"
BASE COUNT           87 a           84 c           80 g           81 t
ORIGIN      
        1 acatggggac attcagatga cccagtctcc gtcctccctg tctgcttctg taggagacag
       61 agtcaccatc acttgccggg caagtcaggg cattagcagt tttttaaatt ggtatcgaca
      121 gaaaccgggg aaacccccta acctcctgat ctattatgca aaccgtttgg aaagtggggt
      181 cccttcaagg ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct
      241 gcaacctgaa gattttgcaa cttattactg tcaacagtat aatagtttac cgctcacttt
      301 cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003037             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19128:6527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003037
VERSION     KCVT01003037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19128:6527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80562.1"
                     /translation="CQQYFSSPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           95 a          128 c          110 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccacgc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agagctggta gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcaccctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagctc cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01003038             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21895:12005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003038
VERSION     KCVT01003038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21895:12005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..317
                     /note="immunoglobulin light chain variable region"
     V_region        28..317
     V_segment       28..265
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <257..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80563.1"
                     /translation="CLQGYDTPYSF"
     J_segment       280..317
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>320
                     /gene="IGKC"
BASE COUNT           84 a           75 c           87 g           74 t
ORIGIN      
        1 acatgggtca acgcagagta catgggggtc tgcatcggta ggagacagag tcaccatcac
       61 ttgccgggca agtcaggaca ttagcgatta tttaagttgg tatcagcaga agccaggaaa
      121 agctcctaac cgcctgatct atgctgcatc cagtttggga agtggggtcc catctaggtt
      181 cagcggcagt ggatctgcga cagaattcac tctcaccatc agcagcctac agcctgaaga
      241 ttttgcagct tattactgtc ttcagggtta tgataccccg tacagttttg gccaggggac
      301 caaagtggag atcaaacgag
//
LOCUS       KCVT01003039             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9496:15774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003039
VERSION     KCVT01003039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9496:15774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80564.1"
                     /translation="CLQYKSFPYTF"
     J_segment       385..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          110 a          115 c           96 g           97 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtggg agacactgtc accatcactt gccggacaag tcaaggtata
      181 accaattatt tacattggtt tcagcagaaa ccagggagaa cccctaagct cctgatctat
      241 gaaacatcca gtttgacaag tggggtccca tcaaggttca gcggcagtgc atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa gtttcccgta tacctttggc caggggacca aactggagat caaacgag
//
LOCUS       KCVT01003040             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22250:16144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003040
VERSION     KCVT01003040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22250:16144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80565.1"
                     /translation="CHQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          117 c          109 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 tcagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003041             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15944:7956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003041
VERSION     KCVT01003041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15944:7956"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..341
                     /note="immunoglobulin light chain variable region"
     V_region        20..341
     V_segment       20..299
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80566.1"
                     /translation="CQQCDSDSLTF"
     J_segment       304..341
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           87 a           88 c           90 g           79 t
ORIGIN      
        1 acatgggggt gccaaatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
       61 tgtaggagac agagtcacca tcacttgtcg ggcgactcag gacattcgca gttatttagc
      121 gtggtatcag cagaaaccag ggaaagcccc gaggcccttg atctattacg cgtccacttt
      181 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      241 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacaat gtgacagtga
      301 ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003042             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6595:13009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003042
VERSION     KCVT01003042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6595:13009"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80567.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggta tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003043             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:25724:8050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003043
VERSION     KCVT01003043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25724:8050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80568.1"
                     /translation="CQQGYTPPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          119 c          113 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcgtct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 gtattagcag ctggttagcc tggtatcagc aggaaccagg gaaagcccct aaactcctga
      241 tctataaggc gtccagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcaacagcc tgcagcctga agattttaca acttattatt
      361 gtcaacaggg ttacactccc cctctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003044             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15591:3849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003044
VERSION     KCVT01003044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15591:3849"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80569.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          118 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaagtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acattgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003045             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:9663:3554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003045
VERSION     KCVT01003045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9663:3554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80570.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           91 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003046             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13873:11231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003046
VERSION     KCVT01003046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13873:11231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80571.1"
                     /translation="CQQYDSDPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagtcc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgctcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01003047             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10397:18267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003047
VERSION     KCVT01003047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10397:18267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80572.1"
                     /translation="CQQYNNDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattagaag ttatttagcg tggtatcaga tgagaccagg gaaagccccg agggccttaa
      241 tctattacgc gaccattttg gaaggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcggcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacaatgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003048             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15416:13098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003048
VERSION     KCVT01003048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15416:13098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80573.1"
                     /translation="CLQESNCSYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tagtaccgga gaaatagtgg tgacacagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcaaa agcaggttag cctggtacca gcagaaacct gggcaagctc ccaggctcct
      241 catgtatgat gcgtccagca gggccactgg catcccagac aggttcactg gcagcgggtc
      301 tgggccagag ttcactctca ccatcagcag cctggagcct gaagatgttg cggtttattt
      361 ctgtcttcag gagagtaact gttcgtacag ctttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003049             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18761:15572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003049
VERSION     KCVT01003049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18761:15572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80574.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01003050             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14554:15478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003050
VERSION     KCVT01003050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14554:15478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80575.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          126 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagttcc cttggacgtt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003051             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14383:9749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003051
VERSION     KCVT01003051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14383:9749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..375
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80576.1"
                     /translation="CQQGYTYPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          122 c          104 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgctcc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca gaaatttaaa ttggtatcaa cagaaaccag ggaaagcccc taaactcctg
      241 ctctataggg catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatactta ccctttcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003052             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17068:15559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003052
VERSION     KCVT01003052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17068:15559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80577.1"
                     /translation="CLQGYSAPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          106 g           97 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgctt cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcaaaaacca ggaaaaactc ctcagcgcct
      241 gatctatgct acatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggttatagtg ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01003053             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:14875:6649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003053
VERSION     KCVT01003053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14875:6649"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80578.1"
                     /translation="CQHGYGIQLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          116 c          111 g           96 t
ORIGIN      
        1 acatgggggt cagtcccagt caggacacag catggacatg agggccccca ctcagctcct
       61 ggggttcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg tgggagacag agtcaccatc tcttgccagg cgagtcagga
      181 cattagcaat gatttagcct ggtatcagca gaaaccggga aaagccccta ggctcctgat
      241 gtataaggca tccgctttgc agattggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcaacagcct gcagcctgaa gattttgcaa cttactactg
      361 tcaacatggt tatggtatcc agctcacttt cggtggaggg accaaggtgg acatcaaacg
      421 ag
//
LOCUS       KCVT01003054             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20867:9607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003054
VERSION     KCVT01003054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20867:9607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..284
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80579.1"
                     /translation="CQQYNSLPYSF"
     J_segment       285..322
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           91 a           75 c           80 g           79 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgtat ctgtaggaga cagagtcacc
       61 atcacttgcc gggcaagtca ggacattagc agttttttaa attggtatca gcagaaaccg
      121 gggaaagccc ctaaggtcct gatctattat gcaaaccgtt tggaaagagg ggtcccatca
      181 aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagtag cctgcaacct
      241 gaggattttg caacttatta ctgtcaacag tataatagtt taccgtacag ttttggccag
      301 gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01003055             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15933:10545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003055
VERSION     KCVT01003055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15933:10545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80580.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca ccctcggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccatccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttgga gtttattact gcatgcaagc tctagaattt ccgctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01003056             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11998:3108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003056
VERSION     KCVT01003056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11998:3108"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80581.1"
                     /translation="CQQGYSFPFTF"
     J_segment       383..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           94 a          123 c          106 g           99 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcacgatc acttgccagg cgagtcaagg
      181 cattggcagt agtttaagct ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctttagggca tccagtttgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct ccagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagtttcc ccttcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01003057             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:22593:16265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003057
VERSION     KCVT01003057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22593:16265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..400
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80582.1"
                     /translation="CQQYNSLPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          111 a          113 c          116 g          101 t
ORIGIN      
        1 acatgggcaa cgcagagtac atggggagtc agacccagtc aggacacagc atggacatga
       61 gggtccccgc tcagctcctg gggctcctgc tgctctggct cccaggtgcc agatgtgaca
      121 ttgagatgac ccagtctcca tcctccctgt ctgcttctgt aggagacaga gtcaccatca
      181 cttgccgggc aagtcagggc gttaacgttt atttaaattg gtatcagcag aaaccgggga
      241 aagcccctaa gcccctgatc ttttatgcaa accgtttgga acgtggggtc ccatcaaggt
      301 tcagcggcag tggatctggg acagaattca ctctcaccat cagcagcctg caacctgaag
      361 attttgcaag ttattattgt caacagtata atagtttacc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003058             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:9222:17212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003058
VERSION     KCVT01003058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9222:17212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80583.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01003059             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19708:17106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003059
VERSION     KCVT01003059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19708:17106"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..394
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80584.1"
                     /translation="CGQGTQLPPTF"
     J_segment       398..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           99 a          122 c          116 g           97 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggttccag tggggatgtt gtgatgactc agtctccact
      121 ctccctgccc atcacccctg gacagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tgttcacatc aatggaaaca catacttgag ttggtatcac cagaagccag gccaacctcc
      241 aaggcgccta atttatgagg tttcttaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 aatttattac tgcgggcaag gtacacagct tcctcccacg ttcggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01003060             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12398:20946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003060
VERSION     KCVT01003060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12398:20946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80585.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          117 c          107 g           94 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt ccctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003061             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24298:14482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003061
VERSION     KCVT01003061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24298:14482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80586.1"
                     /translation="CQQHDDSPRTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          112 a          118 c          103 g           88 t
ORIGIN      
        1 acatggggtc agtctcagac aggacacagc atggacacga gggtccccgc tcagctcctg
       61 gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcagagc cagtcacgat
      181 attaacaact ggttggcctg gtatcaacag aaaccaggga aagcccctaa ggtcctgatc
      241 tatagggcat ccaatttgga aacaggggtc ccatcaaggt tcagtggaag tggttctggg
      301 acagatttca ctctcaccat caacaacctg cagcctgaag atatcgcaac atattactgt
      361 caacaacatg atgattcccc tcggaccttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01003062             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12013:13359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003062
VERSION     KCVT01003062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12013:13359"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80587.1"
                     /translation="CQQGKSIPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          113 c          105 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat tacttgccgg acaagtcagg
      181 gcattagcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccca aaggtcctga
      241 tctattatgc agacagtttg tcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taaaagtatt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01003063             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14409:12816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003063
VERSION     KCVT01003063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14409:12816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80588.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct tgtgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttccttcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc cctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003064             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13573:5820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003064
VERSION     KCVT01003064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13573:5820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80589.1"
                     /translation="CQQHDNSPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          115 c          109 g           89 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcaactgg ttggcctggt atcaacagag accagggaaa gcccctaagt tcctgatcta
      241 tagggcatcc aatttggaga ctgggatccc atcaagattc actggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat aattccccgt ggacgttcgg ccaagggacc aaggtggaag tcaaacgag
//
LOCUS       KCVT01003065             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24845:13911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003065
VERSION     KCVT01003065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24845:13911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..312
                     /note="immunoglobulin light chain variable region"
     V_region        111..312
     V_segment       111..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80590.1"
                     /translation="CMQALDFPWTF"
     J_segment       276..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           70 a           79 c           89 g           77 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat ggccagtctc
      121 cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctagact ttccttggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01003066             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12170:16702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003066
VERSION     KCVT01003066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12170:16702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..343
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80591.1"
                     /translation="CQQYDSDSLTF"
     J_segment       348..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           92 a          107 c           99 g           90 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgac tcaggacatt cgcagttatt tagcgtggta tcagcagaaa
      181 ccagggaaag ccccgaagcc cttgatctat tacgcgtcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcaa cagtatgaca gtgattcgct cactttcggt
      361 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003067             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18339:6729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003067
VERSION     KCVT01003067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18339:6729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80592.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          112 c          111 g          100 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac cattagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003068             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16997:14685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003068
VERSION     KCVT01003068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16997:14685"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80593.1"
                     /translation="CMQAVEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcaat ctcctacagg tctagtcaga
      181 gcctcctgga tagtgaggat gggaacacct atttgacatg gtacctgaag aagcctggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctg tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003069             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:24084:13467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003069
VERSION     KCVT01003069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24084:13467"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80594.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          103 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catccaccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01003070             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24281:8391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003070
VERSION     KCVT01003070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24281:8391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80595.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003071             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12122:3266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003071
VERSION     KCVT01003071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12122:3266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..359
                     /note="immunoglobulin light chain variable region"
     V_region        82..359
     V_segment       82..321
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80596.1"
                     /translation="CEQYNSLPYTF"
     J_segment       322..359
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT          100 a           93 c           90 g           79 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggagacag agtcaccatc acttgccggg caagtcagga
      121 cgttaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      181 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      301 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      361 ag
//
LOCUS       KCVT01003072             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8507:7365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003072
VERSION     KCVT01003072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8507:7365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..402
                     /note="immunoglobulin light chain variable region"
     V_region        111..402
     V_segment       111..364
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <342..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80597.1"
                     /translation="CMQALEFPWTF"
     J_segment       365..402
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>405
                     /gene="IGKC"
BASE COUNT           94 a          101 c          114 g           96 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccatctcctg caggtctagt cagagcctct tggatagtga ggatggaaac acctatttgg
      181 aatggtacct acagaggcca ggccagtctc cacagctctt aatttatgag gtttcctacc
      241 gggcctctgg agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga
      301 aaatcagcag agtggaggct gaggatgttg gggtttatta ctgcatgcaa gctctagagt
      361 ttccgtggac gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01003073             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19015:15686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003073
VERSION     KCVT01003073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19015:15686"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80598.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          117 c          106 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcagcatca gcagcctgca gcctgaagat ttcgcaacat atttctgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003074             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14195:3930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003074
VERSION     KCVT01003074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14195:3930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80599.1"
                     /translation="CMQALEFPLTF"
     J_segment       276..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           80 c           87 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagtctc
      121 cacagctctt gatttatgag gtttccaatc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctagaat ttcctctcac tttcggtgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01003075             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18548:3493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003075
VERSION     KCVT01003075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18548:3493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..383
                     /note="immunoglobulin light chain variable region"
     V_region        110..383
     V_segment       110..345
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80600.1"
                     /translation="CQQYDSFPLTF"
     J_segment       348..383
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           93 a          105 c           99 g           89 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcacttgc cgggctagtc aggacattag taatttttta aattggtatc agcagaaacc
      181 ggggaaagcc cctaagctcc tgatctatta tggaaaccgt ttgggaagcg gggtcccatc
      241 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc
      301 tgaggatttt gcgacttatc attgtcagca gtatgatagt ttccccctca ctttcggccc
      361 cgggaccaaa ctggatatca aacgag
//
LOCUS       KCVT01003076             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19433:17839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003076
VERSION     KCVT01003076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19433:17839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80601.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          122 c          122 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gccactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003077             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19933:20327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003077
VERSION     KCVT01003077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19933:20327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80602.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          120 c          110 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagt cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01003078             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11385:6080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003078
VERSION     KCVT01003078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11385:6080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80603.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatcaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggaat ttatttctgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003079             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17138:4373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003079
VERSION     KCVT01003079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17138:4373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80604.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003080             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17328:6878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003080
VERSION     KCVT01003080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17328:6878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80605.1"
                     /translation="CQRYGYSTWTF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          102 a          119 c          117 g           91 t
ORIGIN      
        1 acatggggag agaagagctg ctcagttagg acccagagag aaccatggaa atcccagctc
       61 agcttctctt cctcctgcta ctgtggctcc caggtaccac cggacaagtt atattgactc
      121 agtctccagc caccctgtct ttgtctccag gggaaagagc caccctctcc tgcagggcca
      181 gtcagaatgt tggcagcagc ttagtttggt accagcagaa acctgggcag gcccccaggc
      241 tcctcatcta tggtgcatcc agcagggcca ctggcatccc agacaggttc agtggcagtg
      301 ggtctgggac agagttcact ctcaccatca gcagcctgga gcctgaagat tttgcagtgt
      361 attactgtca gaggtatggt tactccacgt ggacgttcgg acaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01003081             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24295:3905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003081
VERSION     KCVT01003081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24295:3905"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80606.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcatttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003082             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:25124:13328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003082
VERSION     KCVT01003082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25124:13328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80607.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          117 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctctct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01003083             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:26909:6518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003083
VERSION     KCVT01003083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26909:6518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80608.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          120 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttgttactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003084             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9213:16407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003084
VERSION     KCVT01003084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9213:16407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80609.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003085             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15964:9538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003085
VERSION     KCVT01003085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15964:9538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80610.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          102 t
ORIGIN      
        1 acagggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003086             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:23202:7784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003086
VERSION     KCVT01003086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23202:7784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80611.1"
                     /translation="CQQYFSSPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           94 a          127 c          109 g           94 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccactc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagctc cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01003087             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15521:16374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003087
VERSION     KCVT01003087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15521:16374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80612.1"
                     /translation="CQQYSDFLLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           95 a          126 c          112 g           91 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gatcccagat accgccggag aaattgtcat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa acagccaccc tctcctgcag ggccagtgag
      181 agtgttggca ccttcttagc ctggtaccaa cagaaacctg ggcaggctcc caaactcctt
      241 gtccatagtg cattcttcag ggcccctggc atcccagaca ggttcagtgg cagcgggtct
      301 gggacagagt tcactctcac catcaacacc ctggagcctg aagatgttgg agtttatcac
      361 tgtcagcagt atagtgactt cctgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003088             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6339:7815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003088
VERSION     KCVT01003088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6339:7815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80613.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat gtcctgcagg tccagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggttaggc actgatttca cactggaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003089             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12892:9491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003089
VERSION     KCVT01003089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12892:9491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80614.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          117 c           96 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct acatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaagattc agcggcagtg cttctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attcctgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01003090             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8969:15237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003090
VERSION     KCVT01003090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8969:15237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..274
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80615.1"
                     /translation="CQQYDSDLFTF"
     J_segment       278..313
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           79 a           78 c           84 g           75 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgca tttgtaggag acagagtcac catcacttgt
       61 cgggcgagtc agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc
      121 ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc
      181 ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt
      241 gcaacttatt actgtcaaca gtatgacagt gacctgttca ctttcggtgg agggaccaag
      301 gtggagatca aacgag
//
LOCUS       KCVT01003091             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21961:15701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003091
VERSION     KCVT01003091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21961:15701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80616.1"
                     /translation="CQHSYGTPFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          104 a          114 c          106 g           97 t
ORIGIN      
        1 acatgggggc agtctcagtc aggacacagc atggacatga gggcctctgc tcagctccta
       61 gggctcctgc tgctctggct cccaggcgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtaggac aagtcagaac
      181 gttaacaact atttacattg gtatcagcag aaaccaggga aagcccctag gctcctgatc
      241 tatgctgcgt ccaatttgca aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagatttca ctttcaccat caccagcctg caacctgaag atgttgcaac ttattactgt
      361 cagcatagtt atggtacccc gttcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01003092             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21303:6237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003092
VERSION     KCVT01003092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21303:6237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80617.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           85 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003093             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16477:13377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003093
VERSION     KCVT01003093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16477:13377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80618.1"
                     /translation="CMQSLEFPVTF"
     J_segment       403..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccct ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaatctc tagaatttcc tgtcactttc ggtggaggga
      421 ccagggtgga gatcaatcga g
//
LOCUS       KCVT01003094             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9951:12557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003094
VERSION     KCVT01003094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9951:12557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80619.1"
                     /translation="CQQYNSDTRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca acagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggagattgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag tataacagtg acacgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003095             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22649:7343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003095
VERSION     KCVT01003095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22649:7343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80620.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttggcgtggt atcaccagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01003096             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8664:10541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003096
VERSION     KCVT01003096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8664:10541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80621.1"
                     /translation="CIQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtctgaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca ttcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003097             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10158:4709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003097
VERSION     KCVT01003097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10158:4709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80622.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgttggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003098             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12914:13187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003098
VERSION     KCVT01003098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12914:13187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80623.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttttgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accagggtgg aaatcaaacg ag
//
LOCUS       KCVT01003099             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12886:8093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003099
VERSION     KCVT01003099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12886:8093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80624.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          117 c          121 g          106 t
ORIGIN      
        1 atggggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catacgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003100             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19043:10214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003100
VERSION     KCVT01003100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19043:10214"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80625.1"
                     /translation="CMQNTEDPTF"
     J_segment       399..432
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT          100 a          123 c          110 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctgggt ccagtgggga tattgtgctg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgaa tactaatgga aacacctatt tgcattggta cctgcagaag tcaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcaca gatttcacac tgaaaatcag caccgtggag cctgaggatg
      361 ttggtattta ttactgcatg caaaatacag aagatcccac tttcggcccc gggaccagac
      421 tggatatcaa acgag
//
LOCUS       KCVT01003101             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13543:8005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003101
VERSION     KCVT01003101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13543:8005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80626.1"
                     /translation="CLQYNSSPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          117 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca tagcatggac atgagggtcc ctgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgcc gggcgagtca
      181 gactattagc agctggttag actggtatca gcagaaacca gggaaagccc ctaacctcct
      241 gatctttaag gcatccagtt tgcaaagtgg ggtcccctca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtctacag tacaatagta gcccgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003102             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25943:9965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003102
VERSION     KCVT01003102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25943:9965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80627.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaagggc
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003103             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17166:15337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003103
VERSION     KCVT01003103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17166:15337"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..359
                     /note="immunoglobulin light chain variable region"
     V_region        82..359
     V_segment       82..321
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80628.1"
                     /translation="CQQYNSDPFTF"
     J_segment       322..359
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           97 a           98 c           89 g           78 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggagacag agtaaccatc acttgtcggg cgagtcagga
      121 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaacccccga agcccttgat
      181 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      241 gacagaattc actctcacca tcagcagtct gcagcctgag gattttgcaa cttattactg
      301 tcaacaatat aacagtgacc cattcacttt cggccccggg accaaactgg ataccaaacg
      361 ag
//
LOCUS       KCVT01003104             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8560:13595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003104
VERSION     KCVT01003104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8560:13595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80629.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc actcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003105             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16392:6649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003105
VERSION     KCVT01003105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16392:6649"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80630.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          119 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttttgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc acactgaaac tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003106             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:10356:14420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003106
VERSION     KCVT01003106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10356:14420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..400
                     /gene="IGKV2-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80631.1"
                     /translation="CMQALQTPRTF"
     J_segment       402..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          103 a          118 c          116 g          103 t
ORIGIN      
        1 acatggggga gatcagaact gctcagttca ccttctcaag atgaagttcc atgctcagct
       61 cctgggactg ttaatgctct gggtctctga atccagtggg gatattgtga tgacccagac
      121 tccactctcc ctgcccgtga cccctgggga gccggcctcc atctcctgca ggtctagtca
      181 gagcctccta catagtaatg gaaataccta tttgtattgg tacctgcaga agccagggca
      241 gcctccacgg ctcctaatct atacagtttc cacccggttc tctggagtgc cagacaggtt
      301 cagtggcagt ggatcaggca cagacttcac actgaaaatc agccgggtgg aggctgagga
      361 tgtcgggatt tattactgca tgcaagcttt acagactcct cggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003107             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:26585:20719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003107
VERSION     KCVT01003107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26585:20719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80632.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacaactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003108             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15808:15524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003108
VERSION     KCVT01003108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15808:15524"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..381
                     /note="immunoglobulin light chain variable region"
     V_region        64..381
     V_segment       64..342
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80633.1"
                     /translation="CQQGYSYHPTF"
     J_segment       351..381
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>388
                     /gene="IGKC"
BASE COUNT           83 a          112 c           99 g           94 t
ORIGIN      
        1 acatgggggg tccccgctca gctccttggg ctcctgctgc tctggctccc aggtgccaga
       61 tgtgacttcc ttatgacgca gtctccttcc tccctgtccg catctgtagg agacacagtc
      121 accatcactt gccaggcgag tcaagccatt ggcactaatt taaattggta tcagcagaga
      181 ccaggaaaag cccctaaact cctgatctat agggcttccg gtttgcagag tgggactccc
      241 tctcggttca gcggcagtgg atctgggacg gatttcagtc tcaccatcag cagcctgcag
      301 cctgaagatt ttgccactta ttactgtcaa cagggttata gttaccatcc cactttcggc
      361 ggagggacca aggtggagat ccaacgag
//
LOCUS       KCVT01003109             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20004:7528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003109
VERSION     KCVT01003109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20004:7528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80634.1"
                     /translation="CLQGDTSPFSF"
     J_segment       392..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          114 c          114 g           97 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagcc
      181 aggacattaa cgattattta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatctatgc tgcatccagt ttggagagtg gggtcccatc taggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagtc tgaggatttt gcaacttatt
      361 actgtctaca gggtgatact tccccgttta gtttcggcgg agggacccag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003110             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16249:7794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003110
VERSION     KCVT01003110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16249:7794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80635.1"
                     /translation="CQHSYDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          106 g           96 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg tgggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagtccctg aactcctgat
      241 ctatgctgca tcgtctttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc accctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcatagt tatgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003111             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11214:3128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003111
VERSION     KCVT01003111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11214:3128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80636.1"
                     /translation="CQQYDSFPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          116 c          102 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agttatttaa actggtatca gcagaaaccg gggaaagccc ctaaactcct
      241 gatctattat acaaatcgtt tggaaactgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ctgtcaacag tatgatagtt ttccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01003112             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12361:13813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003112
VERSION     KCVT01003112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12361:13813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80637.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          115 c          106 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcac tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003113             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21423:11141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003113
VERSION     KCVT01003113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21423:11141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80638.1"
                     /translation="CMQALEFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggcacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgacgtt tccagccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cctacagttt tggccagggg
      421 accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01003114             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15130:3545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003114
VERSION     KCVT01003114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15130:3545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..373
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80639.1"
                     /translation="CQQYDKSPPTF"
     J_segment       376..410
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g           83 t
ORIGIN      
        1 acatggggag acaggacaca gcatggacac gagggtcccc gctcagctcc tggggctcct
       61 gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc catcctccct
      121 gtctgcatct gtaggagaca gggtcaccat cacttgcaga gccagtcagg gtatcagcaa
      181 ctggttggcc tggtatcaac agaaaccagg gagagcccct aacctcctga tgtatagggc
      241 gtccaatttg caaggagggg tcccatcaag gttcagagga agtggatctg ggacagattt
      301 cactctcacc atcagcagcc tgcagcctga ggatgtcgct acatattact gtcaacagta
      361 tgataagtcc cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003115             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19859:17033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003115
VERSION     KCVT01003115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19859:17033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80640.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa ctgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa atggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003116             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:15240:8131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003116
VERSION     KCVT01003116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15240:8131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80641.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01003117             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12205:18593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003117
VERSION     KCVT01003117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12205:18593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80642.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01003118             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18923:18007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003118
VERSION     KCVT01003118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18923:18007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80643.1"
                     /translation="CLQYKSYPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          113 c           98 g          102 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatcac ttgccgggca agtcaggtta
      181 ttatcaatta tttaaattgg tttcagcaga aaccagggaa agcccctaag ctcctgattt
      241 atgctgcatc cagattggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtataa aagttaccca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01003119             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15340:8182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003119
VERSION     KCVT01003119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15340:8182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80644.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003120             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13322:10299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003120
VERSION     KCVT01003120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13322:10299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80645.1"
                     /translation="CQQHGNAPWMF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          115 c          117 g           86 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca gcatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcagcag catggcaatg ccccgtggat gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003121             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13793:16738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003121
VERSION     KCVT01003121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13793:16738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80646.1"
                     /translation="CQQYNSDPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          118 c          103 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaaccc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca atataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      421 aacgag
//
LOCUS       KCVT01003122             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20783:7963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003122
VERSION     KCVT01003122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20783:7963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80647.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcaccactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaagt cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagaatttcc gtggacgttc ggcccaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003123             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21700:14086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003123
VERSION     KCVT01003123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21700:14086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..330
                     /note="immunoglobulin light chain variable region"
     V_region        9..330
     V_segment       9..292
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <270..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80648.1"
                     /translation="CLQFKTFPYSF"
     J_segment       293..330
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>333
                     /gene="IGKC"
BASE COUNT           80 a           88 c           80 g           85 t
ORIGIN      
        1 acatggggga catccagatg actcagtctc catcttccct gtctgcatct gtaggagaca
       61 ctgtcaccat ctcttgccgg gcaagtcagg gtattagcag ttctttaagt tggtttcagc
      121 agaaaccagg gaaagcccct aagctcctca tctatgctgc atccactttg gccggtgggg
      181 tcccatcaag gttcagcggc agtggatctg ggacagactt cactctcacc atcagcagcc
      241 tgcagcctga agattttgca acttattact gtctacagtt taaaactttc ccgtacagtt
      301 ttggccaggg gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01003124             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17911:2222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003124
VERSION     KCVT01003124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17911:2222"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..409
                     /note="immunoglobulin light chain variable region"
     V_region        95..409
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80649.1"
                     /translation="CQQHNLYPTF"
     J_segment       383..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>416
                     /gene="IGKC"
BASE COUNT          104 a          112 c          105 g           95 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagttgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcaa gtcagggcat
      181 taacagttat ttagcctggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 taaggcgtcc aatttgaaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca aaagcctgca gcctgaagat tttgcagttt attactgtca
      361 acagcataat ctttacccca cattcggcgg agggaccaag gtagagatcg aacgag
//
LOCUS       KCVT01003125             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16652:7031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003125
VERSION     KCVT01003125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16652:7031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80650.1"
                     /translation="CQQYDSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac atagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003126             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:15004:8810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003126
VERSION     KCVT01003126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15004:8810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..373
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80651.1"
                     /translation="CQQGYYTPFTF"
     J_segment       388..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT           98 a          122 c          111 g           97 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgcccga tgtgacatcc agatgaccca
      121 gtctccatcg tccctgtctg catctgtagg agacaaagtc accatctctt gccgaaccag
      181 tcagggtatt agcagctggt tagcctggta tcagcagaaa ccagggaaag cccctaagct
      241 cctgatctat aaggcgtcca gtttggcaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggacg gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgctactta
      361 ttattgtcaa cagggttact ataccccatt cactttcggc cccgggacca aactggatat
      421 caatcgag
//
LOCUS       KCVT01003127             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8633:7970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003127
VERSION     KCVT01003127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8633:7970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..382
                     /note="immunoglobulin light chain variable region"
     V_region        96..382
     V_segment       96..345
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80652.1"
                     /translation="CLQYKFYPFTF"
     J_segment       346..382
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>386
                     /gene="IGKC"
BASE COUNT           93 a          107 c           88 g           98 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgca ggagacactg tcaccatcac ttgccgggca agtcagggta
      181 ttggttccta tttaaattgg tttcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc tagtctggat ttgggacaga tttcactctc accatcagca gcctgcagcc
      301 tgaagatttc gcaacttatt attgtctaca gtataaattt tatccattca ccttcggccc
      361 cgggaccaaa ctggatatca aaggag
//
LOCUS       KCVT01003128             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:27393:16408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003128
VERSION     KCVT01003128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:27393:16408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80653.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003129             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16962:9047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003129
VERSION     KCVT01003129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16962:9047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80654.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          103 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcaacagaa accaggaaga gcccctaaag tcctgatcta
      241 tagggcctcc agtttacaaa gtgggtttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt atttctgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003130             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10335:7397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003130
VERSION     KCVT01003130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10335:7397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80655.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          119 c          106 g           85 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ccccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003131             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21130:12449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003131
VERSION     KCVT01003131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21130:12449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80656.1"
                     /translation="CQQNSDWRRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          121 c          118 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtatc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatag tgcatccacc agggccactg gcatcccaga caggtttagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtgac tggcgtcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003132             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15132:3354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003132
VERSION     KCVT01003132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15132:3354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80657.1"
                     /translation="CQQYDSDSLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca acgcagagta catgggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003133             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12586:4457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003133
VERSION     KCVT01003133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12586:4457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80658.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          123 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcag ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgagttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003134             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17714:18126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003134
VERSION     KCVT01003134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17714:18126"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..364
                     /note="immunoglobulin light chain variable region"
     V_region        43..364
     V_segment       43..326
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80659.1"
                     /translation="CQHSFRTPYSF"
     J_segment       327..364
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           88 a          100 c           93 g           86 t
ORIGIN      
        1 acatgggggc tcctgctgct ctggctccca ggcgccagat gtgacatcca gatgacccag
       61 tctccatcct ccctgtctgc atctgtagga gacagagtca atgtcacttg cagggctagt
      121 gagagcgtta gcaccaaatt acattggtat cagcagaaac cagggaaagc ccctaagctc
      181 ctgatctttg ctgcgtccac tttgcaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctggaacag atttcactct caccatcagc agcctgcagc ctgaagatgt cgcaactttt
      301 tactgtcagc atagttttcg taccccgtac agttttggcc aggggaccaa agtggagatc
      361 aaacgag
//
LOCUS       KCVT01003135             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19359:22604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003135
VERSION     KCVT01003135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19359:22604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80660.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccctg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01003136             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14058:8968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003136
VERSION     KCVT01003136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14058:8968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80661.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003137             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15210:12725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003137
VERSION     KCVT01003137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15210:12725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80662.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaagga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003138             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23849:8829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003138
VERSION     KCVT01003138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23849:8829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..430
                     /note="immunoglobulin light chain variable region"
     V_region        96..430
     V_segment       96..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80663.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt gggggtgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtccacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctatccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagtagag tggaggctga ggatgttgga
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01003139             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16230:11466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003139
VERSION     KCVT01003139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16230:11466"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..357
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80664.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          115 c          114 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tacacctcca ggagagacag tgtccatctc ctgccaagcc agaccagatg
      181 tacatggtga aataccttgg atccggataa accttgaaca aagacttgaa ccccttttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagcccggtt catcaccaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01003140             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15775:18073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003140
VERSION     KCVT01003140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15775:18073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80665.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003141             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11790:12559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003141
VERSION     KCVT01003141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11790:12559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80666.1"
                     /translation="CQQGDSYPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          113 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatga cattcagatg tcccagtctc
      121 cttcctccct gtctgcatct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagaga ttatttaaat tggtatcagc agcaaccggg gaaagcccct aaactcctga
      241 tgtattatgc aaacagtctg gcaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg tgacagttat cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003142             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13402:22646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003142
VERSION     KCVT01003142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13402:22646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80667.1"
                     /translation="CQQGYSIPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          113 c          108 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgtcccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac cattacttgc cgggcaagtc
      181 agggcattag caattattta aattggtatc agcagaaacc ggggaaagcc ccaaaggtcc
      241 tgatctatta tgcagacagt ttgtcaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gggttatagt attccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01003143             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10616:15059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003143
VERSION     KCVT01003143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10616:15059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80668.1"
                     /translation="CQQVYSTPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          118 c          101 g          101 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccagatgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataatag tttagcgtgg tatcaacaga aaccagggaa agcccctaag ctcctgatct
      241 acgctgcatc cagattacaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttctgcagct tattactgtc
      361 aacaggttta tagtacccca ttcactttcg gccccgggac caaactggat ttcaaacgag
//
LOCUS       KCVT01003144             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6095:9744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003144
VERSION     KCVT01003144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6095:9744"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80669.1"
                     /translation="CQQDFDWPPTF"
     J_segment       384..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           97 a          126 c          110 g           88 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagctccagc acagcttctc
       61 ttcctcctgc tactctggat cccagatacc accggagaag ttgtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccaccctct cctgcagggc cagtcagagt
      181 gttggcaaca ccttaacctg gtaccagcac aaacctgggc aggctcccaa gctcctcctc
      241 tatggtgcat ccaccagggc ctccggcatc ccaggcaggt tcagtgccag tgggtctgga
      301 acagagttta ctctcaccat cagcagcctg gagcctgaag atgttggaat ttattactgt
      361 cagcaggatt ttgactggcc tccgacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01003145             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10729:18407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003145
VERSION     KCVT01003145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10729:18407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80670.1"
                     /translation="CMQSIKDPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          101 a          120 c          110 g          108 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tccagtgggg atattgtgat gacccagacc
      121 ccactcttgg tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctcc atagtaatgg agacacctat ttacattggt accttcagag gtcaggccag
      241 tctccacggc tcctgatcta taaagtaacc aatcggctac ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 attggtgttt atttctgcat gcaaagtata aaagatccat tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01003146             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19328:15446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003146
VERSION     KCVT01003146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19328:15446"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80671.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003147             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16791:17674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003147
VERSION     KCVT01003147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16791:17674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..341
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80672.1"
                     /translation="CLQGYNIPYNF"
     J_segment       356..393
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           95 a          101 c          103 g           97 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc ttctggtgct ccttctgctc tggctcccag
       61 gtgccagatg tgacatccag ttgacccagt ctccatcttc cctgtctgca tcggtaggag
      121 acagagtcac catcacttgc cgggcaagtc aggacattag cgattattta agttggtatc
      181 agcagaaacc aggaaaagct cctaagcgcc tgatctatgc tgtgtccagt ttggaaggtg
      241 gggtcccatc aagattcagc ggcagtggat ctgggacaga attcactctc accatcagca
      301 gcctgcagcc tgaagatttt gcgacttatt actgtctaca gggttataat atcccgtaca
      361 attttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01003148             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17218:10342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003148
VERSION     KCVT01003148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17218:10342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80673.1"
                     /translation="CQQGYGFPFTF"
     J_segment       383..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           96 a          127 c          104 g           95 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg caggagacag agtcaccatc acttgcaggg caagtgagaa
      181 cgttcacaac tatttacatt ggtatcagca gaagccaggg aaagccccta gcctcctgat
      241 ctatgctgca tccactttgc aaagtggggt cccatccagg ttcagcggca gtggatctgg
      301 ggcagatttc actctcacca tcagcagcct gcagcctgaa gatgttgcca cttattactg
      361 tcaacaaggt tatggcttcc ctttcacctt cggccccggg accacactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01003149             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15731:16602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003149
VERSION     KCVT01003149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15731:16602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80674.1"
                     /translation="CMQALEFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          123 c          115 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atgaaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagtagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccattcactt tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01003150             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11202:7431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003150
VERSION     KCVT01003150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11202:7431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..385
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80675.1"
                     /translation="CLQYKSFPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          113 c          103 g          101 t
ORIGIN      
        1 acatggggag gagtcagaca cagtcaggac acagcatgga catgagggcc cccgctcatc
       61 tcctagggct cctgctgctc tggctcccag gtgccagatg tggcatccag atgactcagt
      121 ctccatcttc cctgtctgca tctgtgggag acactgtcac catcacttgc cggacaagtc
      181 aaggtattac caattattta cattggtttc agcagaaacc agggaaagcc cctaagctcc
      241 tgatctatga aacatccagt ttggtaagtg gggtcccatc aaggttcagc ggcagtgcat
      301 ctgggacaga attcactctc accatcagca gcctacagcc tgaagatttt gcatcttatt
      361 actgtctaca gtataaaagt ttcccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01003151             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16626:8043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003151
VERSION     KCVT01003151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16626:8043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..403
                     /note="immunoglobulin light chain variable region"
     V_region        82..403
     V_segment       82..365
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80676.1"
                     /translation="CQQYNSLPFTF"
     J_segment       372..403
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT          100 a          110 c           98 g           98 t
ORIGIN      
        1 acatggggac acagcatgga cataagggtc cccgctcagc tcctggggct cctgctgctc
       61 tggctcccag gtgccagatg tgacattcag atgacccagt ctccatcctc cctgtctgct
      121 tctgtaggag acagagtcac catcacttgc cggacaagtc agggcatttt cagttattta
      181 acttggtatc agcagaaacc ggggaaagcc cctaaactcc tgatctatta tgcaaaccgt
      241 ttggacaatg gggtcccatc aaggttcagc ggcagtggat ctgggaccga attcactctc
      301 accatcagcg gcctgcagcc tgaagatttt gcaacttatt actgtcaaca atataatagt
      361 ttaccgttca cttttggcca ggggaccaca gtggagatca aacgag
//
LOCUS       KCVT01003152             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22086:18815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003152
VERSION     KCVT01003152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22086:18815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..238
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80677.1"
                     /translation="CQQHDDSPRTF"
     J_segment       240..275
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           82 a           71 c           68 g           57 t
ORIGIN      
        1 acatggggtc accatcactt gcacagccag ccacgatata aataactggt tggcctggta
       61 tcaacagaaa ccaggaaaag cccctaagct cctgatctat agggcatcca atttggaaac
      121 aggggtccca tcgaggttca gtggaagtgg atctgggaca gatttcactc tcagcatcag
      181 cagcctgcag cctgaagatt tcgcaacata ttactgtcaa cagcatgatg attcccctcg
      241 gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003153             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19391:12152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003153
VERSION     KCVT01003153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19391:12152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80678.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          122 c          115 g          105 t
ORIGIN      
        1 acttgactga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgagga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003154             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12169:16385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003154
VERSION     KCVT01003154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12169:16385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80679.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacgt atttggattg gtacctgcag aagccaggcc
      241 agtctccgca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgacaat tagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003155             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10245:10640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003155
VERSION     KCVT01003155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10245:10640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80680.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003156             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6832:18841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003156
VERSION     KCVT01003156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6832:18841"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80681.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003157             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7521:10154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003157
VERSION     KCVT01003157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7521:10154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80682.1"
                     /translation="CQQDFGWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          120 c          122 g           92 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagactgttg gcagcgcctt agcctggtac cagcagaaac ctgggcagac
      241 tcacaaactc ctcatttatg gtgtatccag cagggccacc ggcatcccag acaggttcag
      301 tggcagtggg tctggaacag agttcactct caccatcagt agtccggagc ctgaggatgt
      361 tggagtttat tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01003158             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24106:9826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003158
VERSION     KCVT01003158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24106:9826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80683.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          108 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtgt tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 tagcctcttg gatggtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01003159             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:8450:13633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003159
VERSION     KCVT01003159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8450:13633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80684.1"
                     /translation="CQQYDSDSLTF"
     J_segment       378..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           93 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac tcaggacatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003160             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9083:18010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003160
VERSION     KCVT01003160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9083:18010"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80685.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          106 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa actagggaaa gccccgaatc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattccc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003161             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20814:8903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003161
VERSION     KCVT01003161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20814:8903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80686.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          122 c          113 g           86 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcttagcctg gtaccagcag aaacctgggc aggctcccag gctcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccagacaggt tcagtgacag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcagt ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01003162             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15220:13683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003162
VERSION     KCVT01003162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15220:13683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80687.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctaca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01003163             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14100:9500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003163
VERSION     KCVT01003163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14100:9500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80688.1"
                     /translation="CQQYSSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          120 c          103 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcac ttttttaaat tggtatcaac agaaaccggg gaaagcccct aagctcctga
      241 tctattattc aaaccgtttg gagactgggg tcccatcaag gttcagcgcc ggtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca gcatatcact
      361 gtcaacagta tagtagtttt ccgctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01003164             291 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8705:7050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003164
VERSION     KCVT01003164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 291)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8705:7050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..251
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <228..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80689.1"
                     /translation="CMQALEFPRTF"
     J_segment       253..284
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>291
                     /gene="IGKC"
BASE COUNT           70 a           68 c           85 g           68 t
ORIGIN      
        1 acatgggcat ctcctgcagg tctagtcaga gtctcttgga tagtgcggat ggaaacacct
       61 atttggactg gtacctgcag aagccaggcc agtctccaca gctcttgatt tatgaggtct
      121 ccgaccgggc ctctggagtc ccagacaggt tcagtggcag tggctcagac actgatttca
      181 cactgaaaat cagcagagtg gaggctgaag atgttgggat ttattactgc atgcaagctc
      241 tagagtttcc tcggacgttc ggccagggga ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01003165             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15977:10510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003165
VERSION     KCVT01003165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15977:10510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80690.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>440
                     /gene="IGKC"
BASE COUNT           90 a          121 c          122 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cggtggggac attgtgatga cccaggctcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagactct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcagacgag
//
LOCUS       KCVT01003166             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11997:4799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003166
VERSION     KCVT01003166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11997:4799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80691.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          117 c          123 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtga cccttagaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaggccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003167             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14102:10386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003167
VERSION     KCVT01003167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14102:10386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80692.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgcgga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cagtgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggcccaggga
      421 ccaaggtgga catcaaacga g
//
LOCUS       KCVT01003168             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17441:13791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003168
VERSION     KCVT01003168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17441:13791"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80693.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          114 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003169             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7773:8674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003169
VERSION     KCVT01003169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7773:8674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80694.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01003170             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18741:9909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003170
VERSION     KCVT01003170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18741:9909"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..255
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <233..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80695.1"
                     /translation="CLQGDTTPFTF"
     J_segment       262..282
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>296
                     /gene="IGKC"
BASE COUNT           78 a           73 c           77 g           68 t
ORIGIN      
        1 acatggggca tcggtaggag acagagtcac catcacttgc cgggcaagtc aggacattag
       61 cgattattta agttggtatc agcagaaacc gggaaaagct cctaagcgcc taatctatgc
      121 tgcctccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat ctgagacagt
      181 gttcactctc accatcagca gcctgcagcc tgaagatttt gcgacttatt actgtctaca
      241 gggtgatact accccgttca cttttggcca ggggaccaaa gtagacgtca aacgag
//
LOCUS       KCVT01003171             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15331:18578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003171
VERSION     KCVT01003171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15331:18578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80696.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagac ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaggccaggc
      241 cagtctccac agctcttgat ttttgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003172             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16764:13466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003172
VERSION     KCVT01003172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16764:13466"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..415
                     /note="immunoglobulin light chain variable region"
     V_region        96..415
     V_segment       96..380
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80697.1"
                     /translation="CQQHNSYPRTF"
     J_segment       382..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>420
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           91 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtacca gatgtgacat ccagatgacc cagtctccat
      121 cttccttgtc tgcatctgta ggagacagag tcaccatcac ttgccaagcc agtcagggta
      181 ttggcaactg gttagcctgg tatcggcaga aaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc cagtttacaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 agcagcataa tagttatcct cggacgttcg gccaagggac caaggtggaa atcaagcgag
//
LOCUS       KCVT01003173             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25375:12878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003173
VERSION     KCVT01003173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25375:12878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80698.1"
                     /translation="CEQYNSLPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          110 a          112 c          102 g           97 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 gttaacattt atttaaattg gtatcaccag aaaccgggga aagcccctaa gctcctgatc
      241 tattatacaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattactgt
      361 gaacaataca atagtttacc gtacactttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01003174             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10965:17505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003174
VERSION     KCVT01003174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10965:17505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80699.1"
                     /translation="CQQYNSLPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          111 c          104 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgtcag atgtgacatt cagatgaccc agtctccatc
      121 caccctgtcc gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtaattat ttaaattggt atcagcaaaa accggggaat gcccctaaac tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggatc agcggcagtg gatccgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttacccc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003175             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12993:18104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003175
VERSION     KCVT01003175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12993:18104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80700.1"
                     /translation="CGQGTHLPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           94 a          125 c          121 g           94 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccac tggggatgtt gtgatgactc agtctccgct
      121 ctccctgccc atcacccctg gacagccggc ctccgtctcc tgcaggtcta gtcaaagcct
      181 tgtgcacagc gatggaaaca catacttgac ttggtatcaa cagaagccag gccaacctcc
      241 aaggcgccta atttttgagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg acgatgttgg
      361 ggtttattac tgcggccaag gtacacacct tccgtggacg ttcggccaag ggaccacggt
      421 ggaactcaaa cgag
//
LOCUS       KCVT01003176             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4333:12691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003176
VERSION     KCVT01003176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4333:12691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80701.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          101 a          122 c          113 g           85 t
ORIGIN      
        1 atgggggaac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcgtagcctg gtaccagcaa aaacctgggc aggctcccag actcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01003177             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8736:13818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003177
VERSION     KCVT01003177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8736:13818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80702.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01003178             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7774:12238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003178
VERSION     KCVT01003178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7774:12238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80703.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcaaca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003179             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9495:9699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003179
VERSION     KCVT01003179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9495:9699"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80704.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tccagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003180             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17254:17846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003180
VERSION     KCVT01003180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17254:17846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80705.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          123 c          116 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcaaaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01003181             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:21047:17763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003181
VERSION     KCVT01003181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21047:17763"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80706.1"
                     /translation="CQQHDNSPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          116 c          111 g           87 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagag
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaggccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gataattccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003182             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7798:18183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003182
VERSION     KCVT01003182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7798:18183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80707.1"
                     /translation="CQHSHGSPITF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgagaa
      181 cgtttacaac tatttacatt ggtatcagca gaaaccaggg aaagccccta aggtcctgat
      241 ctatgctgca tccactttgc aaagtggagt cccatcaagg ttcagcggca gtggatctgg
      301 gactgatttc actctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcatagt catggatccc ctatcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003183             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13989:13383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003183
VERSION     KCVT01003183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13989:13383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80708.1"
                     /translation="CQQGYSFPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           95 a          123 c          107 g           99 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca gtagtttaag ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctttaggg catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctccagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagttt ccccttcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003184             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22027:13335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003184
VERSION     KCVT01003184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22027:13335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80709.1"
                     /translation="CQQYDSDLFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          118 c          117 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catttgtcgg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttact tagcgtggta tcagcagaga ccagggaaag ccccgaagcc
      241 cttgatctac tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcgactta
      361 ttactgtcag cagtatgaca gtgacctgtt cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003185             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16410:13227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003185
VERSION     KCVT01003185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16410:13227"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80710.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003186             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24990:4588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003186
VERSION     KCVT01003186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24990:4588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80711.1"
                     /translation="CQQYDSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          112 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003187             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13148:17773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003187
VERSION     KCVT01003187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13148:17773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80712.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           85 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003188             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9931:10129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003188
VERSION     KCVT01003188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9931:10129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80713.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          121 c          123 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttcca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagcgt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003189             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11770:15717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003189
VERSION     KCVT01003189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11770:15717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..403
                     /note="immunoglobulin light chain variable region"
     V_region        82..403
     V_segment       82..365
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80714.1"
                     /translation="CQQYNSLPYSF"
     J_segment       366..403
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT          101 a          104 c          104 g           97 t
ORIGIN      
        1 acatggggac acagcatgga catgagggtc cccgctcagc tcctggggct cctgctgctc
       61 tggctcccag gtgccagatg tgacattgag atgacccagt ctccatcctc cctgtctgct
      121 tctgtaggag acagagtcac catcacttgc cgggcaagtc agggcgttaa cgtttattta
      181 aattggtatc aacagaaacc ggggaaagcc cctaagcccc tgatctttta tgcaaaccgt
      241 ttggaacgtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga attcactctc
      301 accatcagca gcctgcaacc tgaagatttt gcaagttatt attgtcaaca gtataatagt
      361 ttaccgtaca gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01003190             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12776:10554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003190
VERSION     KCVT01003190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12776:10554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80715.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003191             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:6561:6661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003191
VERSION     KCVT01003191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6561:6661"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80716.1"
                     /translation="CLQGDTAPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           95 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagaagtgac atccagatga cccagtctcc
      121 atcttccctg tctgcgtcgg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattaacgat tatttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat
      241 ctatgctgca tccagtttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagtagtct gctgcctgaa gattttgcaa cttattactg
      361 tctacagggt gatactgccc cgctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003192             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12682:16895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003192
VERSION     KCVT01003192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12682:16895"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80717.1"
                     /translation="CMQSLEIPPTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           92 a          121 c          121 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctgggtcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtggggatgg aaacacctat ttggattggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc acccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggcgttt attactgcat gcaatctcta gagattcctc ccactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01003193             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13755:22695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003193
VERSION     KCVT01003193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13755:22695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80718.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          108 c          110 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagata gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003194             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21183:9712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003194
VERSION     KCVT01003194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21183:9712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..393
                     /note="immunoglobulin light chain variable region"
     V_region        125..393
     V_segment       125..356
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80719.1"
                     /translation="CQQDYHWPPTF"
     J_segment       359..393
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           97 a          115 c          105 g           79 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctctcctgc agggccagtc agagtgttgg cagcacctta acctggtacc
      181 accagaagcc tgggcaggct cccaagctcc tcatctatgg tccatccatc agggccagcg
      241 gcatcccaga caggttcagt ggcagtgggt ctggaacaga atttactctc accatcagca
      301 gcctggagac tgaagatgtt ggagtttatt actgtcagca ggattatcac tggcctccga
      361 cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01003195             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14744:14631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003195
VERSION     KCVT01003195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14744:14631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80720.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          121 c          121 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagcca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003196             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17537:14814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003196
VERSION     KCVT01003196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17537:14814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80721.1"
                     /translation="CQHSFDTPYTF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          117 c          107 g           95 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgcgaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agtccctgag ctcctgatct
      241 atgctgcatc gtctttgcaa agtggggtcc catcaaggtt cagcggcagt gggtctggga
      301 cagatttcac cctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcacagttt tgataccccc tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003197             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21633:16676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003197
VERSION     KCVT01003197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21633:16676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80722.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagaa actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003198             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10278:9820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003198
VERSION     KCVT01003198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10278:9820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80723.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003199             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6903:2519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003199
VERSION     KCVT01003199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6903:2519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80724.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaagttt ccaaccgggc ctctggagtc ccagataggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003200             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17858:7527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003200
VERSION     KCVT01003200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17858:7527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80725.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          110 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcga cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003201             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:10721:13126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003201
VERSION     KCVT01003201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10721:13126"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80726.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 cttcagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003202             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21200:10987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003202
VERSION     KCVT01003202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21200:10987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80727.1"
                     /translation="CLQYKTFPYTF"
     J_segment       390..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          118 c          100 g           99 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggggaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtattaccaa ttatttacat tggtttcagc agaaaccagg gagagcccct aagctcctga
      241 tctatgaaac atccagtttg acaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggtcagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaactttc ccgtacacct ttggccaggg gaccagactg gagatcaaac
      421 gag
//
LOCUS       KCVT01003203             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7829:20690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003203
VERSION     KCVT01003203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7829:20690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80728.1"
                     /translation="CQQYNNLPLSF"
     J_segment       383..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          109 c          101 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccggacaa gtcaggacat
      181 taacgtttat ttaaattggt atcaacagaa accggggaaa gcccctaacc tcctgatcta
      241 ttatgcaaac cgtttggaaa gaggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat aatttaccgt tgagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003204             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:8207:7234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003204
VERSION     KCVT01003204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8207:7234"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..405
                     /note="immunoglobulin light chain variable region"
     V_region        84..405
     V_segment       84..367
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80729.1"
                     /translation="CQQYDNDPLTF"
     J_segment       368..405
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT          103 a          112 c          103 g           90 t
ORIGIN      
        1 acatgggagg acacagcatg gacatgaggg tccccgctca gctcctagga ctcctgctgc
       61 tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc tccctgtctg
      121 catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt cgcagttatt
      181 tagcgtggta tcaacagaaa ccagggaaag ccccgaagcc cttgatctat tacgcgtcca
      241 ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc
      301 tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa caatatgaca
      361 atgacccgct cactttcggt ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01003205             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:16969:6830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003205
VERSION     KCVT01003205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16969:6830"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80730.1"
                     /translation="CQQYNSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          108 c          113 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccattaat tgtcgggcga gtcaggacat
      181 tagtagttat ttagcgtggt atcggcagag gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcattatca gcagcctgca gcctgaagat tttggaactt attactgtca
      361 acagtataac agtgactcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003206             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:9161:12757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003206
VERSION     KCVT01003206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9161:12757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80731.1"
                     /translation="CQQGNSNPVTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          112 c          112 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggggaca gagtcaccat cacttgccgg gcaagtcagc
      181 ccattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tatattatgc aagtagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga agactttgca acttattact
      361 gtcagcaggg caatagtaat cctgtcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003207             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14859:7911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003207
VERSION     KCVT01003207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14859:7911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80732.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtcc gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagag accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaacct attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003208             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12517:8993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003208
VERSION     KCVT01003208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12517:8993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80733.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          118 c          108 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003209             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14677:12183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003209
VERSION     KCVT01003209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14677:12183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80734.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg tatttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01003210             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18793:7251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003210
VERSION     KCVT01003210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18793:7251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80735.1"
                     /translation="CMQPLDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca gccttggaga gccggcctcc attttctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaacc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003211             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19841:16169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003211
VERSION     KCVT01003211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19841:16169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    132..415
                     /note="immunoglobulin light chain variable region"
     V_region        132..415
     V_segment       132..377
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80736.1"
                     /translation="CMQPLEFPWTF"
     J_segment       378..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           97 a          110 c          112 g           99 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccac tctccatctc ctgcaggtct agtcagagcc tcttggatag tgaggatgga
      181 aacacctatt tggaatggta cctacagaag ccaggccagt ctccacagct cttgatttat
      241 gaggtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact
      301 gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta ttactgcatg
      361 caacctctag agtttccgtg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003212             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:24675:16825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003212
VERSION     KCVT01003212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24675:16825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..276
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80737.1"
                     /translation="CMQALEFPLTF"
     J_segment       277..313
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           76 a           75 c           89 g           76 t
ORIGIN      
        1 acatgggccg tcacccttgg agagccggcc tccatctcct gcaggtctag tcagaacctc
       61 ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc aggccagtct
      121 ccacagctct tgatttatga ggtttccaat cgggcctctg gagtcccaga caggttcagt
      181 ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggagcc tgaggatgtt
      241 ggggtttatt actgcatgca agctctagaa tttcctctca ctttcggtgg agggaccaag
      301 gtggagatca aacgag
//
LOCUS       KCVT01003213             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:21350:12528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003213
VERSION     KCVT01003213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21350:12528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80738.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggggcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003214             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12321:11195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003214
VERSION     KCVT01003214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12321:11195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80739.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          126 c          119 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac caacaaaaac ctgggcaggc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01003215             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14482:13312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003215
VERSION     KCVT01003215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14482:13312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80740.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           93 a          125 c          116 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag atctcaccgg agaagtggtg atgacgcagt
      121 ctccagccac cctgtctttg tctcctgggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cggctcctta gcctggtacc agcagaaacc tgggcaggct ccccaactcc
      241 tcatctatgc tgcatccacc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga ctttactctc actatcagca gtctggagcc tgaagatgtt ggattttatt
      361 tctgtcagca ggattatcac tggcctccga cgttcggcca aggggccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003216             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12517:4105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003216
VERSION     KCVT01003216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12517:4105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80741.1"
                     /translation="CQHSFDTPYTF"
     J_segment       386..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          118 c          109 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtgc
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagtcc ctgagctcct
      241 gatctatgct gcatcgtctt tgcaaagtgg ggtcccatca aggttcagcg gcagtgggtc
      301 tgggacagat ttcaccctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcac agttttgata ccccctacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003217             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11124:17898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003217
VERSION     KCVT01003217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11124:17898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80742.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac attgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003218             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:20926:3109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003218
VERSION     KCVT01003218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20926:3109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80743.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           99 a          116 c          117 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga caacctccta
      241 aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac gatggtgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accatggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01003219             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17643:16148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003219
VERSION     KCVT01003219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17643:16148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..356
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80744.1"
                     /translation="CQQHDNSPPTF"
     J_segment       359..393
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           96 a          109 c          102 g           89 t
ORIGIN      
        1 acatggggga cacgagggtc cccgctcagc tcctggggct cctgttgctc tggctcccag
       61 gtgccagatg tgacatccag atgacccagt ctccttcctc cctgtctgca tctataggcg
      121 acagagtcac catcacttgc agagccagtc agggtattag cgactggttg gcctggtatc
      181 aacagaaacc agggaaagcc cctaaactcc tgatctatag ggcatccaat ttggaaacag
      241 gggtcccatc aaggttcagt ggaagtggat ctgggacaga tttcactctc accatcagca
      301 gcctgcaggc tgaagatttc gcaacatatt tctgtcaaca gcatgataat tcccctccca
      361 ctttcggtgg agggactaag gtggagatca aacgag
//
LOCUS       KCVT01003220             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12804:14415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003220
VERSION     KCVT01003220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12804:14415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80745.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggtcc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003221             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10142:7807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003221
VERSION     KCVT01003221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10142:7807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80746.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaagtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01003222             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25802:7970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003222
VERSION     KCVT01003222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25802:7970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80747.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          120 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgtt aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccaaagtgga gattaaacga g
//
LOCUS       KCVT01003223             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:7316:8780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003223
VERSION     KCVT01003223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7316:8780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..387
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80748.1"
                     /translation="CQQRNGYPYMISF"
     J_segment       397..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          105 a          112 c          116 g          101 t
ORIGIN      
        1 acatgggggc aggagttaga cccagtctgg acgcagcatg gacatcaggg tcctcgctca
       61 gcttctcggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agttgataca
      121 gtctccatcc tccctgtctg cgtctgtagg agacagagtc accatcactt gtcgggcaag
      181 tcaggacatt aacagttatt tagcctggta tcaacagaaa ccagggaaag cccctaagct
      241 cctgatctat agggcgtcca gtttgcaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcagttta
      361 ttactgtcaa cagcggaatg gttacccgta catgatcagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01003224             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24329:10796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003224
VERSION     KCVT01003224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24329:10796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80749.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcttggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctatttcgc atccactttg gaaagtggcg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003225             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10528:19717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003225
VERSION     KCVT01003225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10528:19717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80750.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgagc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003226             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21426:5557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003226
VERSION     KCVT01003226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21426:5557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..399
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80751.1"
                     /translation="CMQGLQTPYTF"
     J_segment       400..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          105 t
ORIGIN      
        1 acatgggggt gatcaggact cctcagttca ccttgtcaca atgaggctcc ctgctcagct
       61 cctggggctg ctaatgctct gggtctctgc ctccagtgga gatatcgtga tgacccagac
      121 tccactctcg ctgcccgtca cccttggaga gccagcctcc atctcctgca ggtctagtca
      181 gagccttctg aatagtaatg gatacagcta tttgagttgg tacctgcaga ggccaggcca
      241 gtctccacat ctgctgatct attatggctc tagtcgggcc tccggggtcc ccgacaggtt
      301 cagtggcagt gggtcaggca cagattttac actgaaaatc accagggtgg aggctgacga
      361 cgtaggggtt tattactgca tgcaaggtct acaaactccg tacacttttg gccaggggac
      421 caaagtggag atcaaacgag
//
LOCUS       KCVT01003227             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23124:7221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003227
VERSION     KCVT01003227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23124:7221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80752.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003228             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20783:8002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003228
VERSION     KCVT01003228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20783:8002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..250
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80753.1"
                     /translation="CQQHDDSPRTF"
     J_segment       252..287
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           87 a           68 c           73 g           62 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgcacagcc agtcaggata ttaataactg
       61 gttggcctgg tatcaacaga aaccaggaaa agcccctaaa ctcctgatct atagggcatc
      121 taatttggaa acaggggtcc catcgaggtt cggtggaagt ggatctggga cagattttac
      181 tctcaccatt agcagcctgc agcctgaaga tatcgcaaca tattactgtc aacagcatga
      241 tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01003229             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6292:15777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003229
VERSION     KCVT01003229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6292:15777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80754.1"
                     /translation="CLQDVQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           86 a          123 c          122 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtggcga tattgtgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctccttca tagtaatgga aacacctatt tgttttggta cctgcagagg ccaggccagt
      241 ccccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatgtac agcttcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01003230             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19412:15395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003230
VERSION     KCVT01003230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19412:15395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80755.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01003231             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22882:18695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003231
VERSION     KCVT01003231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22882:18695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80756.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc atcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003232             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18717:1949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003232
VERSION     KCVT01003232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18717:1949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80757.1"
                     /translation="CLQESNWSYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          120 c          119 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tagtaccgga gaaatagtgg tgacacagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcaaa agcaggttag cctggtacca gcagaaacct gggcaagctc ccaggctcct
      241 catgtatgat gcgtccagca gggccactgg catcccagac aggttcactg gcagcgggtc
      301 tgggccagag ttcactctca ccatcagcag cctggagcct gaagatgttg cggtttattt
      361 ctgtcttcag gagagtaact ggtcgtacag ctttagccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003233             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12076:9404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003233
VERSION     KCVT01003233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12076:9404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..395
                     /note="immunoglobulin light chain variable region"
     V_region        74..395
     V_segment       74..348
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80758.1"
                     /translation="CQQHNNYSPTF"
     J_segment       361..395
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>398
                     /gene="IGKC"
BASE COUNT           97 a          112 c          100 g           89 t
ORIGIN      
        1 acatgggatg gacatgaggg tccccgctca gctcctgggg ctcctgctgc tctggctccc
       61 aggtgccaga tgtgacatcc agatgaccca gtctccaccc tccctgtctg catctgtagg
      121 agacacagtc accatcactt gtcgggcaag tcagggcatt agcaatgatt tagcctggta
      181 tcagctgaaa ccagggaaag ccccgaagcc cctgatctat tacgcatcca atttggaaag
      241 tggggtccca tcaaggttca gcggcagtgg atctgggaca gatttcactc tcaccatcag
      301 cagcctgcag cctgaagatt ttgcaactta ttactgtcaa cagcataata attactctcc
      361 cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003234             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:26772:19031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003234
VERSION     KCVT01003234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:26772:19031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80759.1"
                     /translation="CIQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atacaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003235             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11642:14984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003235
VERSION     KCVT01003235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11642:14984"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80760.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003236             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14417:12811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003236
VERSION     KCVT01003236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14417:12811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80761.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          127 c          123 g           87 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag
      121 tgctgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagct tagcctggta ccagcagaga cctgggcagg
      241 ctcccagact cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca
      301 gtggcagtgg gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg
      361 ttgcacttta ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01003237             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12252:6391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003237
VERSION     KCVT01003237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12252:6391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80762.1"
                     /translation="CQQYNTDPPTF"
     J_segment       387..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          126 c          104 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcccccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagca gtcatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg catccatttt ggaaagtggg gtcccatcaa ggttccgcgg cagtggatct
      301 gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacactga ccctcccact ttcggccccg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003238             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9632:8373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003238
VERSION     KCVT01003238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9632:8373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80763.1"
                     /translation="CQQNSNWPLTF"
     J_segment       379..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           98 a          121 c          114 g           85 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ccccagcaca gcttctcttc
       61 ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca gtctccagcc
      121 accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag tcagagtgtc
      181 agcagcagct tagcctggta ccagcagaaa cctgggcagg ctcccaggct cctcatctat
      241 ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg gtctgggaca
      301 gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcagttta ttattgtcag
      361 cagaatagta actggcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003239             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:26159:11133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003239
VERSION     KCVT01003239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26159:11133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..421
                     /note="immunoglobulin light chain variable region"
     V_region        82..421
     V_segment       82..383
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80764.1"
                     /translation="CMQALDFPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           91 a          116 c          117 g          100 t
ORIGIN      
        1 acatggggtc accttctcac aatgaggctc cctgctcagc tcctgggact gctaatgctc
       61 tggctccctg gatgcagtgg ggacattgtg atgacccaga ctccactctc cctgcccgtc
      121 acccttggag agccggcctc catctcctgc aggtctagtc agagcctctt ggatagtgag
      181 gatggaaaca cctatttgga atggtacctg cagaagccag gccagtctcc acagctcttg
      241 atttatgagg tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca
      301 gacactgatt tcacactgaa aatcagcaga gtggaggctg cggatgttgg ggtttattac
      361 tgcatgcaag ctctagactt tcccctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003240             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10111:13216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003240
VERSION     KCVT01003240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10111:13216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80765.1"
                     /translation="CQQSYRYPLTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          100 a          115 c          107 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaaac tcctgatgtt
      241 tcttgcatcc actttgcaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcgccatca gcagcctgca gcctgaagat gctgcaactt attactgtca
      361 gcagagttat cgttatccgc tcactttcgg tggagggacc caggtggaaa tcaatcgag
//
LOCUS       KCVT01003241             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11553:6822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003241
VERSION     KCVT01003241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11553:6822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80766.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa gccagggaaa gccccgaagc ccttgatcta
      241 ttatgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003242             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19717:10478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003242
VERSION     KCVT01003242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19717:10478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80767.1"
                     /translation="CQQYNSLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          108 a          112 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatccg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgga acttattact
      361 gtcaacagta taatagttta ccacggacgt tcggccaagg gaccaaggtg gagatcagac
      421 gag
//
LOCUS       KCVT01003243             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20582:19339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003243
VERSION     KCVT01003243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20582:19339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80768.1"
                     /translation="CQQDFDWPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          127 c          110 g           87 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagctcca gcacagcttc
       61 tcttcctcct gctactctgg atcccagata ccaccggaga agttgtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcaa caccttaacc tggtaccagc acaaacctgg gcaggctccc aagctcctcc
      241 tctatggtgc atccaccagg gcccccggca tcccagacag gttcagtgcc agtgggtctg
      301 gaacagagtt tactctcacc atcagcagcc tggagcctga agatgttgga atttattact
      361 gtcagcagga ttttgactgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003244             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24532:8396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003244
VERSION     KCVT01003244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24532:8396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80769.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          122 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tgctgaggat ggaaacacct acttggaatg gtctttccag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaagttgga gatcaaacga g
//
LOCUS       KCVT01003245             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21912:11814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003245
VERSION     KCVT01003245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21912:11814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..445
                     /note="immunoglobulin light chain variable region"
     V_region        121..445
     V_segment       121..407
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80770.1"
                     /translation="CQQGNSIPLTF"
     J_segment       408..445
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT          114 a          116 c          112 g          106 t
ORIGIN      
        1 acatgggggt tcattttaag aagaggtacg tttagcctgt gacagggctc agctaacata
       61 atggattttc aggctcaaat tttcatcttc cttctgctca gtgtcacagt gtccaatgga
      121 gaaattgtgc tgacccagtc tccaacatcc atggctgtct cccaaggaga aagagtcacc
      181 atctcctgca cggccagttc aagtgtaagc accagctacc tgcactggta ccaacagaag
      241 ccaggattcc ctccaaggct tcttgtccat agaacatcaa gtctggcttc tggggtccca
      301 gccaggttca gtggcagcgg ttctgggacc tcttacacgc tcacaatcag cagcatggag
      361 gctgaagatg ctgcaaacta ttactgtcag caggggaata gcattccgct cactttcggc
      421 ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003246             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15092:10961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003246
VERSION     KCVT01003246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15092:10961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80771.1"
                     /translation="CQQGNSIPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          106 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 gtcctccctg tctgcatctg tcggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaat tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattatgca gacagtttgt caagtggggt cccatccagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagggt aatagtattc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01003247             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16834:16040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003247
VERSION     KCVT01003247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16834:16040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80772.1"
                     /translation="CLQFKTYPNSF"
     J_segment       386..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           97 a          118 c          106 g          103 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tctcttgccg ggcaagtcag
      181 ggtattagca gttctttaag ttggtttcag cagaaaccag ggaaagcccc tcagctcctc
      241 atctatgctg catccagttt ggccggtggg gtcccatcaa gtttcagcgg cagtggatct
      301 gggacagaat tctctctcac catcaccagc ctgcagcctg aagattttgc aacttatttc
      361 tgtctgcagt ttaaaactta cccgaacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003248             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6827:11762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003248
VERSION     KCVT01003248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6827:11762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..297
                     /note="immunoglobulin light chain variable region"
     V_region        143..297
     V_segment       143..259
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80773.1"
                     /translation="CMQALQFPWTF"
     J_segment       260..297
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           66 a           81 c           84 g           69 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cagacaggtt cagtggcagt gggtcagaca
      181 ctgatttcac tctgaatatc agcagagtgg aggctgagga tgttggggtt tattactgca
      241 tgcaagctct acaatttccg tggacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003249             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16121:9597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003249
VERSION     KCVT01003249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16121:9597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..235
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80774.1"
                     /translation="CQQGYYTPWTF"
     J_segment       250..287
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           78 a           73 c           77 g           62 t
ORIGIN      
        1 acatggggta ggagacaaag tcaccatcac ttgccgagcc agtcagggta ttagcagctg
       61 gttagcctgg tatcagcaga aaccagggaa agcccctaga ctcctgatct ataaggcgtc
      121 cactttggca agtggggtcc catcaacctt cagcggcagt ggatctggga cggattacac
      181 tctcaccatc aacaggctgc agcctgaaga ttttgctact tattattgtc aacagggtta
      241 ctataccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01003250             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16469:10531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003250
VERSION     KCVT01003250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16469:10531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80775.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          114 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt cctgtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003251             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15850:23527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003251
VERSION     KCVT01003251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15850:23527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..446
                     /note="immunoglobulin light chain variable region"
     V_region        125..446
     V_segment       125..408
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80776.1"
                     /translation="CQQGVTFPLTF"
     J_segment       409..446
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>449
                     /gene="IGKC"
BASE COUNT          108 a          117 c          117 g          107 t
ORIGIN      
        1 acatggggag aggctctttc tctgggatgt ggcatgagca aaactgacaa gtcaaggcag
       61 gaagatgttg tctccatcac aactcattgg gtttctgctg ctctgggttc cagcctccaa
      121 gggtgaaatt gtgctgactc agtctccagc ctttcggtct gtgactctaa aggaaaaagt
      181 caccatcacc tgccaggcca gtcagagcat tggtactggc ttacactggt atcagcagaa
      241 accggatcag tctccaaagc tcctcatcac gtatgcttcc cagtccatct caggggtccc
      301 ctcaaggttc agtggcagtg gatctgggac agaattcacc ctcaccatca atagcctgga
      361 agctgaagat gctgcgacgt attactgtca gcagggtgtt actttcccgc tcactttcgg
      421 cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003252             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16141:20479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003252
VERSION     KCVT01003252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16141:20479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80777.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactcaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003253             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16415:16061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003253
VERSION     KCVT01003253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16415:16061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80778.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag ttggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003254             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9797:10517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003254
VERSION     KCVT01003254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9797:10517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80779.1"
                     /translation="YMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactac atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003255             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6610:21478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003255
VERSION     KCVT01003255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6610:21478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80780.1"
                     /translation="CMQTLEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          122 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccggtgg ggacattgtg atgacccagg
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacttatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg cgtttattac tgcatgcaaa ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003256             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14211:12211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003256
VERSION     KCVT01003256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14211:12211"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..318
                     /note="immunoglobulin light chain variable region"
     V_region        8..318
     V_segment       8..276
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80781.1"
                     /translation="CQQYDSDSLTF"
     J_segment       281..318
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           83 a           83 c           82 g           73 t
ORIGIN      
        1 acatggggac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
       61 cttgtcgggc gagtcagggc attcgcagtt atttagcgtg gtatcagcag aaaccaggga
      121 aagccccgaa gcccttgatc tattacgcgt ccactttgga aagtggggtc ccatcaagat
      181 tcagcggcag tggatctggg acagaattca ctctcaccat caacagcctg cagcctgaag
      241 attttgcaac ttattactgt caacagtatg acagtgactc gctcactttc ggtggaggga
      301 ccaaggtaga gatcaaacga g
//
LOCUS       KCVT01003257             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15466:9161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003257
VERSION     KCVT01003257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15466:9161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80782.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcacctta acctggtacc accagaagcc tgggcaggct cccaaactcc
      241 tcatctatgg tccatccatc agggccagcg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga atttactctc accatcagca gcctggagac tgaagatgtt ggagtttatt
      361 actgtcagca ggattatcac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003258             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13722:20421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003258
VERSION     KCVT01003258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13722:20421"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80783.1"
                     /translation="CLQYKSFPYTF"
     J_segment       404..434
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          111 a          122 c          103 g          101 t
ORIGIN      
        1 acatggggac acttcttgca ggagtcagac acagtcagga cacagcatgg acatgagggc
       61 ccccgctcat ctcctagggc tcctgctgct ctggctccca ggtgccagat gtgacatcca
      121 gatgactcag tctccatctt ccctgtctgc atctgtggga gacactgtca ccatcacttg
      181 ccggacaagt caaggtatta ccaattattt acactggttt cagcagaaac cagggagagc
      241 ccctaagctc ctggtctatg aaacatccag tttgacaagt ggggtcccat caaggttcag
      301 cggcagtgca tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt
      361 tgcaacttat tactgtctac agtataaaag tttcccgtac acctttggcc aggggaccaa
      421 actggagatc aaacgag
//
LOCUS       KCVT01003259             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17103:11730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003259
VERSION     KCVT01003259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17103:11730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80784.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggtc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003260             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18358:9028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003260
VERSION     KCVT01003260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18358:9028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80785.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           85 t
ORIGIN      
        1 atggggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc aacagcttag cctggtacca acaaaaacct gggcagcctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagag gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003261             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20910:6609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003261
VERSION     KCVT01003261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20910:6609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80786.1"
                     /translation="CQHSFRSPYSF"
     J_segment       379..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          106 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccgtcact tgcagggcta gtgagagcgt
      181 taacaccaaa ttacattggt atcaacagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttgcaaa gtggggtccc atcaaggttc agcggcaatg gatctggaac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt tttactgtca
      361 gcatagtttt cgttccccgt acagttttgg ccaggggacc aaagtggaga tcagacgag
//
LOCUS       KCVT01003262             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17791:14411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003262
VERSION     KCVT01003262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17791:14411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80787.1"
                     /translation="CEQYNSLPYTF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          110 a          111 c          101 g           95 t
ORIGIN      
        1 acggggagac ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctggggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct
      121 ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacatta
      181 acatttattt aaattggtat caccagaaac cggggaaagc ccctaagctc ctgatctatt
      241 atacaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat tactgtgaac
      361 aatacaatag tttaccgtac acttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01003263             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:26476:15673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003263
VERSION     KCVT01003263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26476:15673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..428
                     /note="immunoglobulin light chain variable region"
     V_region        92..428
     V_segment       92..390
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80788.1"
                     /translation="CGQGTHLPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g           94 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg ggatgttgtg atgactcagt ctccactctc
      121 cctgtccatc acccctggac agccggcctc catctcctgc aggtctagtc aaagccttgt
      181 acacatcaat ggaaacacat acttgagttg gtatcagcag aacccaggcc aacctccaag
      241 gcgcctaatt tatgaggttt ctaaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gaggctgagg atgttgggct
      361 ttattactgc gggcaaggta cacaccttcc gtggacgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01003264             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12395:10396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003264
VERSION     KCVT01003264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12395:10396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80789.1"
                     /translation="CMQAREFPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           97 a          125 c          115 g          100 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agattccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttcgatagt gaggagggga acacctattt ggaatggtac ctacagaagc caggccagtc
      241 tccacaactc ttgatttatg aggtctccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgc
      361 tggggtttat tactgcatgc aagctcgaga gtttccattc actttcggcc ccgggaccaa
      421 actggacatc aaacgag
//
LOCUS       KCVT01003265             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12712:15079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003265
VERSION     KCVT01003265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12712:15079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..297
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80790.1"
                     /translation="CQQHNGYPPTF"
     J_segment       310..344
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           92 a           95 c           83 g           77 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
       61 atctgtagga gacacagtca ccatcacttg tcgggcaagt cagggcatta cgaatgattt
      121 agcctggtat caacagaaac caggtaaagc cccgaagccc ctgatctatt acgcatccaa
      181 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tattgtcaac agcataatgg
      301 ataccctccg acgttcggcc aagggaccag ggtggaaatc aaacgag
//
LOCUS       KCVT01003266             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14027:9869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003266
VERSION     KCVT01003266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14027:9869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..402
                     /note="immunoglobulin light chain variable region"
     V_region        100..402
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80791.1"
                     /translation="CQKYSSSPFTF"
     J_segment       384..402
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           86 a          120 c          106 g           90 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatttt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcaggcccc cagactcctc
      241 gtctatggtg catccaggag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagaagt atagtagttc cccattcact ttcggccccg gg
//
LOCUS       KCVT01003267             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19578:10444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003267
VERSION     KCVT01003267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19578:10444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..383
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80792.1"
                     /translation="CQQYDDYPWTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          101 a          116 c          114 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac aaagtcacca tcacttgcca tgccagtcag
      181 ggtattagta gtcggttagt ctggtatcag cagaaaccag ggaaagcccc taagcccctg
      241 atgtatgctg catccagttt acacagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtcaacagt atgatgatta cccgtggacg ttcggccaag ggaccaaggt ggaaatcaag
      421 cgag
//
LOCUS       KCVT01003268             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15528:9402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003268
VERSION     KCVT01003268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15528:9402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80793.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catacgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003269             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5799:10722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003269
VERSION     KCVT01003269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5799:10722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80794.1"
                     /translation="CQQYDSFPLTF"
     J_segment       388..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          117 c          109 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccactcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtgggag acagagtcac catcacttgc cgggctagtc
      181 aggacattag taatttttta aattggtatc agcagaaacc ggggaaagcc cctaagctcc
      241 tgatctatta tggaaaccgt ttgggaagcg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaggatttt gcgacttatc
      361 attgtcagca gtatgatagt ttccccctca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01003270             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18286:12299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003270
VERSION     KCVT01003270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18286:12299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..370
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80795.1"
                     /translation="CQQYYSFPITF"
     J_segment       384..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>422
                     /gene="IGKC"
BASE COUNT           99 a          113 c          112 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagttcct
       61 ggggctcctg ctgctctgga tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg tgggagacaa agtcaccatc acttgccgag ccagtcaggg
      181 tattaacacc tggttaattt ggtatcagca gaaaccaggg aaagccccta aggccctgat
      241 ctataaggca tccagtttgc aaggtggggt cccttccagg ttcagcggca gtggatctgg
      301 ggcagacttc actctcacca tcaccaacct gcagcctgaa gattttggaa tttattactg
      361 tcaacaatat tatagttttc cgatcacttt cggtgggggg accaaggtgg agatcaggcg
      421 ag
//
LOCUS       KCVT01003271             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:9935:14287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003271
VERSION     KCVT01003271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9935:14287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..442
                     /note="immunoglobulin light chain variable region"
     V_region        121..442
     V_segment       121..404
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80796.1"
                     /translation="CQQYNSDPRTF"
     J_segment       408..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          109 a          123 c          118 g           95 t
ORIGIN      
        1 acatgggagg ctaggcacgc ttcatgcagg agtcagaccc agtcaggaca cagcatggac
       61 atgagggtcc ccgctcagct cctaggactc ctgctgctct gtctcccagg tgccaaatgt
      121 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc
      181 atcacttgtc gggcgagtca gggcattcgc agttatttag cgtggtatca gcagaaacca
      241 gggaaagccc cgaagccctt gatctattac gcgtccactt tggaaagtgg ggtcccatca
      301 aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag cctgcagcct
      361 gaagattttg caacttatta ctgtcaacag tataacagtg acccgcgcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01003272             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8163:15366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003272
VERSION     KCVT01003272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8163:15366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80797.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003273             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22413:17412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003273
VERSION     KCVT01003273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22413:17412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80798.1"
                     /translation="CQQHDNMPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          114 c          116 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgca gggccagtca
      181 gggtattagc aactggttgg cctggtatca acagaaacca gggaaagccc ctaagctcct
      241 gatctatagg gcatggaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 cgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgataata tgccgctcac tttcggtgga gggaccaagg tggacatcaa
      421 acgag
//
LOCUS       KCVT01003274             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21932:10062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003274
VERSION     KCVT01003274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21932:10062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80799.1"
                     /translation="CLQYKNFPLSF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          111 c          105 g          102 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tgggcatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca ggtgtgacat ccagatgact cagtctccgt
      121 cttccctgtc tgcatctcta ggagacactg tcaccatcac ttgccgggca agtcaggata
      181 ttaacagtta tttaaattgg tttcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atggtgcatc cagtttggaa agtgaggtcc cattaagatt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tatttctgtc
      361 tacagtataa aaatttcccg ctctctttcg gcggagggac cagggtggac atcaaacgag
//
LOCUS       KCVT01003275             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23334:9450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003275
VERSION     KCVT01003275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23334:9450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80800.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          121 c          116 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt cttcaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catgtatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003276             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9309:6134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003276
VERSION     KCVT01003276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9309:6134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80801.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          120 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003277             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16980:17684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003277
VERSION     KCVT01003277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16980:17684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80802.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003278             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10025:3088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003278
VERSION     KCVT01003278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10025:3088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80803.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta cttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01003279             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16121:11092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003279
VERSION     KCVT01003279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16121:11092"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80804.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01003280             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25581:14740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003280
VERSION     KCVT01003280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25581:14740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..387
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80805.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       397..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>434
                     /gene="IGKC"
BASE COUNT          102 a          117 c          114 g          101 t
ORIGIN      
        1 acatgggggc aggagttaga cccagtctgg acgcagcatg gacatcaggg tcctcgctca
       61 gcttctcggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agttgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcaag
      181 tcaggacatt ggcaattatt tagcctggta tcagcagaaa ccagggaaag cccctaacct
      241 cctgatctat aaggcgtcca gtttacaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcagttta
      361 ttactgtcaa cagcgtaata gttacccgta catgtgcagt tttggcccgg ggaccaaagt
      421 ggagatccga cgag
//
LOCUS       KCVT01003281             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10315:6955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003281
VERSION     KCVT01003281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10315:6955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80806.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          127 c          111 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga gagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctttggt acatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tcgaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003282             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23155:17853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003282
VERSION     KCVT01003282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23155:17853"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80807.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          122 c          123 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttc cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tctccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcagc gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003283             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15243:10149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003283
VERSION     KCVT01003283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15243:10149"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80808.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggtc tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatctagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgaag tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01003284             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8778:4044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003284
VERSION     KCVT01003284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8778:4044"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80809.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtcaagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttgcact ggtacttgaa gaagccaggc
      241 cagtctccac agctcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003285             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18560:12032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003285
VERSION     KCVT01003285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18560:12032"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80810.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01003286             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19027:8924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003286
VERSION     KCVT01003286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19027:8924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..275
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80811.1"
                     /translation="CQQYNSLPFTF"
     J_segment       278..313
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           83 a           74 c           80 g           79 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgc
       61 cgggcaagtc agggcattag cgtttattta aattggtatc agcagaaacc ggggaaagcc
      121 cctaagctcc tgatctatta tgcaaaccgt ttggaaagtg gggtcccatc aaggttcagc
      181 ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc tgaggatttt
      241 gtaggttatt actgtcaaca gtataatagt ttaccgttca ctttcggtgg agggaccaag
      301 gtggagatca aacgag
//
LOCUS       KCVT01003287             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10866:20104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003287
VERSION     KCVT01003287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10866:20104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80812.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatctagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 ggcagtctcc acaactcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01003288             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14388:9650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003288
VERSION     KCVT01003288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14388:9650"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..277
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80813.1"
                     /translation="CQQYNNDPPTF"
     J_segment       280..314
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>317
                     /gene="IGKC"
BASE COUNT           82 a           88 c           76 g           71 t
ORIGIN      
        1 acatgggcag tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg
       61 tcgggcgagt cagggcattg gcagtcattt agcgtggtat cagcagaaac cagggaaagc
      121 cccgaagccc ttgatctatt acgcatccaa tttggaaagt ggggtcccat caaggttcag
      181 cggcagtgga tctgggacag acttcactct caccatcagc agcctgcagc ctgaagattt
      241 tgcaacttat tactgtcaac agtataacaa tgaccctccc actttcggcc ccgggaccaa
      301 actggatatc aaacgag
//
LOCUS       KCVT01003289             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:4396:16609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003289
VERSION     KCVT01003289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4396:16609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80814.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003290             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24115:10053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003290
VERSION     KCVT01003290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24115:10053"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80815.1"
                     /translation="CMQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           85 a          124 c          123 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgctg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagagg ccaggccagt
      241 ctccacaact tctggtctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caagatatac agcttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01003291             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17415:19305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003291
VERSION     KCVT01003291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17415:19305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80816.1"
                     /translation="CQHHNTYPHSF"
     J_segment       385..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          120 c          106 g           89 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctca gctcagctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aggcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtcaacacca taatacttac cctcacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003292             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19218:13022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003292
VERSION     KCVT01003292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19218:13022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80817.1"
                     /translation="CQQYDSDPFSF"
     J_segment       384..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tctctttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01003293             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13692:17913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003293
VERSION     KCVT01003293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13692:17913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80818.1"
                     /translation="CQQYNSLPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          109 c          110 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcattagt tattatttaa attggtatca acagaaaccg gggaaagccc ctaaggtcct
      241 gatctattac acaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaggattttg caagttatta
      361 ctgtcaacaa tataatagtt taccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003294             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17722:9266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003294
VERSION     KCVT01003294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17722:9266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80819.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          122 c          124 g          101 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccctggag agccggcctc cgtctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatctgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgact tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgtatgcaag cactggagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01003295             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10863:17613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003295
VERSION     KCVT01003295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10863:17613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80820.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          119 c          109 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagcca
      181 cgatataaat aactggttgg cctggtatca acagaaacca ggaaaagccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003296             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23933:4827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003296
VERSION     KCVT01003296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23933:4827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80821.1"
                     /translation="CLQGYTIPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          114 c          107 g           95 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg acaagtcagg
      181 gcattagcga ttatttaagt tggtatcagc agaaaccagg aaaagctcct aagcgcctga
      241 tccatgctgt atccagtttg gaaagtgggg ccccatcaag gttcagcggc agtggatctg
      301 aaacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacaggg ttatactatc ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003297             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:26013:11272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003297
VERSION     KCVT01003297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26013:11272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80822.1"
                     /translation="CEQYNSLPYTF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          113 a          113 c          105 g           97 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctgactccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacgtt aacatttatt taaattggta tcaccagaaa ccggggaaag cccctaagct
      241 cctgatctat tatacaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta
      361 ttactgtgaa caatacaata gtttaccgta cacttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01003298             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:5305:14826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003298
VERSION     KCVT01003298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:5305:14826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80823.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          122 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatatca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctgc ggatgttggg
      361 ctttattact gcgggcaagg aacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01003299             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14013:13562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003299
VERSION     KCVT01003299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14013:13562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80824.1"
                     /translation="CQQYNSDPFTF"
     J_segment       381..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          109 a          118 c          100 g           94 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtaaccatca cttgtcgggc gagtcaggac
      181 ataagaagtt atttagcgtg gtatcagcag aaaccaggca aacccccgaa gcccttgatc
      241 tattacgcat ccgttttgga aagtggggtc ccatcaaggt tcagtggcag tggatctggg
      301 acagaattca ctctcaccat cagcagtctg cagcctgagg attttgcaac ttattactgt
      361 caacaatata acagtgaccc attcactttc ggccccggga ccaaactgga taccaaacga
      421 g
//
LOCUS       KCVT01003300             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19728:9540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003300
VERSION     KCVT01003300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19728:9540"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80825.1"
                     /translation="CQHSYDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          106 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagtccctg agctcctgat
      241 ctatgctgca tcgtctttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc accctcacca tcagtagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcatagt tatgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003301             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16655:20198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003301
VERSION     KCVT01003301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16655:20198"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80826.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          117 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgatgat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003302             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:7884:12918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003302
VERSION     KCVT01003302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:7884:12918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80827.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          125 c          111 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga caaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcagactc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003303             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23704:9204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003303
VERSION     KCVT01003303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23704:9204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80828.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003304             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10507:11813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003304
VERSION     KCVT01003304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10507:11813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80829.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctggtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01003305             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16212:17575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003305
VERSION     KCVT01003305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16212:17575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80830.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003306             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24956:9711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003306
VERSION     KCVT01003306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24956:9711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80831.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          114 c          102 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacgtc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcattc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003307             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17342:13729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003307
VERSION     KCVT01003307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17342:13729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80832.1"
                     /translation="CQQYNNDPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          112 c          114 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccagg tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 ggacattaga agttatttag cgtggtatca gatgagacca gggaaagccc cgagggcctt
      241 aatctattac gcgaccattt tggaaggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcggcag cctgcagcct gaggattttg caacttattt
      361 ctgtcaacag tataacaatg acccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003308             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:27677:9597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003308
VERSION     KCVT01003308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:27677:9597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80833.1"
                     /translation="CQQHDDSPRTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          117 c          107 g           89 t
ORIGIN      
        1 acatgggggc agtctcagac aggacacagc atggacacga gggtccccgc tcagctcctg
       61 gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcacagc cagtcagggt
      181 attaataact ggttggcctg gtatcaacag aaaccaggaa aagcccctaa actccttatc
      241 tatagggcat ccaatttgga aacaggggtc ccatcgaggt tcggtggaag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg cagcctgaag atatcgcaac atatttctgt
      361 caacagcatg atgattcccc tcggacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01003309             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24341:2632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003309
VERSION     KCVT01003309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24341:2632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..322
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80834.1"
                     /translation="CMQALEFPLTF"
     J_segment       323..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           84 a           89 c          104 g           85 t
ORIGIN      
        1 acatggggga tccagtgcgg acattgtgat gacccagact ccactctccc tggccgtcac
       61 tcttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga
      121 tggaaacacc tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat
      181 ttatgaggtt tccaaccggg cctctggagt cccagacagg atcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct ctagagtttc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      361 ag
//
LOCUS       KCVT01003310             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22180:10589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003310
VERSION     KCVT01003310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22180:10589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80835.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccgcttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003311             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10750:18761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003311
VERSION     KCVT01003311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10750:18761"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80836.1"
                     /translation="CQQYDSDLFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           97 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catttgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggtgtccca tcaaggttca gcggcagtgg
      301 ttctgggaca gaattcactc tcaccatcaa cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacctgtt cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003312             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25281:13619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003312
VERSION     KCVT01003312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25281:13619"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    18..295
                     /note="immunoglobulin light chain variable region"
     V_region        18..295
     V_segment       18..257
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <235..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80837.1"
                     /translation="CMQALEFPYSF"
     J_segment       259..295
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>298
                     /gene="IGKC"
BASE COUNT           75 a           67 c           87 g           69 t
ORIGIN      
        1 acatgggggg atcacgactc ctgcaggtct agtcagagcc tcttggatag tgaggatgga
       61 aacacctatt tggagtggca cctgcagaag ccaggccagt ctccacaact cttgatttat
      121 gacgtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact
      181 gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta ttactgcatg
      241 caagctctag agtttcccta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01003313             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11554:17525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003313
VERSION     KCVT01003313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11554:17525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80838.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccattg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003314             533 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22358:9279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003314
VERSION     KCVT01003314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 533)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22358:9279"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    197..530
                     /note="immunoglobulin light chain variable region"
     V_region        197..530
     V_segment       197..492
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <470..>502
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80839.1"
                     /translation="CLQTKNSPWTF"
     J_segment       493..530
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        531..>533
                     /gene="IGKC"
BASE COUNT          125 a          143 c          139 g          126 t
ORIGIN      
        1 acatggggac caacccaaac ttttctgagc tgatttgcat gttgggtcat taggcagcag
       61 tccaagctgc ttagagcatc cttacaggca gcttgtcagg ggccctgagg agcagcctct
      121 agttcagctc tcagaaatgg ggtcctgggc tcctttcctg tggatcctcc tgctctgtgc
      181 tccaggctgc aatggggaca ttgtgctgac ccagtctcca gcctctttgg ccgtgtctcc
      241 agggcagagg gccaccatca cctgcagagc cagtgagagt gtcagtgtct ttggaataaa
      301 cctcattcac tggtatcagc agaaaccagg acaacctcct aaatccctga tttaccaagc
      361 atccaataaa gacactgggg tcccagccag gttcagcggc agtgggtctg ggaccgattt
      421 caccctcaca attaatcctg tggaagctga cgatgctgca gattattact gtctgcagac
      481 taagaattct ccgtggacgt ttggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003315             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19345:17801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003315
VERSION     KCVT01003315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19345:17801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80840.1"
                     /translation="CMQGTQLPYSF"
     J_segment       275..312
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           71 a           77 c           92 g           75 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tggggctact ggtgctctgg ctccctggga ccagtggaga tattgtgatg acccagactc
      121 cacagctctt gatctatttg ggttccaaac gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc aggcactgat ttcacactaa aaatcagtcg ggtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa ggtacacagc ttccgtacag ttttggccag gggaccaaag
      301 tggagatcaa acgag
//
LOCUS       KCVT01003316             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9750:12729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003316
VERSION     KCVT01003316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9750:12729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80841.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003317             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:26735:13128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003317
VERSION     KCVT01003317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26735:13128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80842.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01003318             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15998:11013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003318
VERSION     KCVT01003318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15998:11013"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80843.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          117 c          122 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc cctgacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003319             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23450:8707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003319
VERSION     KCVT01003319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23450:8707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80844.1"
                     /translation="CQHSYDTPYTF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          106 g           96 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgcgaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agtccctgag ctcctgatct
      241 atgctgcatc gtctttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac cctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtta tgatactccc tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003320             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11601:6026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003320
VERSION     KCVT01003320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11601:6026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80845.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctctttga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003321             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15775:16621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003321
VERSION     KCVT01003321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15775:16621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80846.1"
                     /translation="CQQYNSGPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          118 c          101 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagc caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtgcc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtggc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01003322             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:25399:12399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003322
VERSION     KCVT01003322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25399:12399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80847.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          118 c          107 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 atattaatac ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003323             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17317:14429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003323
VERSION     KCVT01003323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17317:14429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80848.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgttggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003324             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14102:21492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003324
VERSION     KCVT01003324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14102:21492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80849.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          124 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaactgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01003325             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14243:14789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003325
VERSION     KCVT01003325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14243:14789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80850.1"
                     /translation="CQQSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          117 c          102 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctctag gagacagcgt caccatcact tgcaggacaa gtgcgagcgt
      181 taataactat ttacattggt atcagcggaa accagggaaa gcccctgaac tcctgatcta
      241 tgctgcatcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctggaac
      301 agatttcact ctcaccatca gcagcctgca gtctgaagat gttgcaactt attactgtca
      361 gcaaagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003326             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23888:12894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003326
VERSION     KCVT01003326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23888:12894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80851.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctctagag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003327             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15214:15168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003327
VERSION     KCVT01003327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15214:15168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80852.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcatctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattctgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgaaga tggaaacacc tatttgcact ggtacctgaa gaagccaggc
      241 cagtctccac agctcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003328             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8174:19879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003328
VERSION     KCVT01003328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8174:19879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80853.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003329             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12535:2096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003329
VERSION     KCVT01003329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12535:2096"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80854.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gaggctgagg
      361 atgttgggct ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga ggtcaaacga g
//
LOCUS       KCVT01003330             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11067:5413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003330
VERSION     KCVT01003330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11067:5413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80855.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          119 c          119 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccaaag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003331             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12993:19841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003331
VERSION     KCVT01003331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12993:19841"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..431
                     /note="immunoglobulin light chain variable region"
     V_region        113..431
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80856.1"
                     /translation="CQQYFSSPFTF"
     J_segment       397..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>437
                     /gene="IGKC"
BASE COUNT           97 a          130 c          114 g           96 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat
      121 attgactcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagagac ctgggcaggc
      241 ccccaggctc ctcatctatg gttcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcagtgtat tactgtcagc agtattttag ctccccattc actttcggcc ccgggaccaa
      421 actggatatc agacgag
//
LOCUS       KCVT01003332             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5619:11646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003332
VERSION     KCVT01003332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5619:11646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80857.1"
                     /translation="CQQYNSLPWTF"
     J_segment       367..404
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT          111 a          103 c          103 g           90 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcag
       61 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct ccctgtctgc
      121 atctgtagga gacagagtca ccatcacttg ccgggcaagt cagggcatta gttattattt
      181 aaattggtat caacagaaac cggggaaagc ccctaaggtc ctgatctatt acacaaaccg
      241 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcaac ctgaggattt tgcaagttat tactgtcaac aatataatag
      361 tttaccgtgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01003333             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:8130:12777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003333
VERSION     KCVT01003333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:8130:12777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80858.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c          102 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag taaccatcac ttgtcgggcg agtcaggaca
      181 taagaagtta tttagcgtgg tatcagcaga aaccaggcaa agccccgaag cccttgatct
      241 attacgcatc cgttttggaa agtggggtcc catcaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagac tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003334             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12160:4921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003334
VERSION     KCVT01003334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12160:4921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80859.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcctct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgc aactggtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttatcact
      361 gtcaacagta taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaagc
      421 gag
//
LOCUS       KCVT01003335             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22710:18731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003335
VERSION     KCVT01003335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22710:18731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80860.1"
                     /translation="CQQHDNSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          112 a          119 c          106 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagccac
      181 gatataaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgataattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01003336             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12139:14450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003336
VERSION     KCVT01003336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12139:14450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80861.1"
                     /translation="CLQYRSYPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          105 g           96 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 tagcagttat ttaaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataga agttacccgt acaattttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003337             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12284:10461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003337
VERSION     KCVT01003337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12284:10461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..325
                     /note="immunoglobulin light chain variable region"
     V_region        8..325
     V_segment       8..287
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <265..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80862.1"
                     /translation="CMQALEFPWTF"
     J_segment       288..325
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>328
                     /gene="IGKC"
BASE COUNT           76 a           80 c           95 g           77 t
ORIGIN      
        1 acatgggcac tctccctgcc cgtcaccctt ggagagccgg cctccatgtc ctgcaggtct
       61 agtcagagtc tcttggatag tgaggatgga aacacctatt tggaatggta cctgcagaag
      121 ccaggccagt ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca
      181 gacaggttca gtggcggtgg gtcagacact gatttcacac tgaaaatcag cagagtggag
      241 gctgatgatg ttggggttta ttactgcatg caagctctag agtttccgtg gacgttcggc
      301 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003338             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24569:5202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003338
VERSION     KCVT01003338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24569:5202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80863.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          107 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcactcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01003339             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19635:12737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003339
VERSION     KCVT01003339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19635:12737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80864.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          109 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg acatcaaacg ag
//
LOCUS       KCVT01003340             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:11386:14734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003340
VERSION     KCVT01003340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11386:14734"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80865.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaggccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca atatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003341             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:29048:15170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003341
VERSION     KCVT01003341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:29048:15170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..330
                     /note="immunoglobulin light chain variable region"
     V_region        9..330
     V_segment       9..293
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <270..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80866.1"
                     /translation="CQQNSNWPLTF"
     J_segment       294..330
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>333
                     /gene="IGKC"
BASE COUNT           82 a           92 c           90 g           69 t
ORIGIN      
        1 acatgggaga aatagtgatg acgcagtctc cagccaccct gtctttgtct ccaggagaaa
       61 gagccaccct ctcctgcagg gccagtcaga gtgtcagcag cagcttagcc tggtaccaac
      121 aaaaacctgg gcaggctccc aggctcctca tctatggtgc atccagcagg gccactggca
      181 tcccagacag gttcagtggc agtgggtctg ggacagactt cactctcacc atcaccagcc
      241 tggagcctga agatgttgca gtttattatt gtcagcagaa tagtaactgg cctctcactt
      301 tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01003342             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11856:14050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003342
VERSION     KCVT01003342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11856:14050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80867.1"
                     /translation="CMQAREFPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           98 a          124 c          116 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggccatctc ctgcaggtct agtcagagcc
      181 tcttcgatag tgaggagggg aacacctatt tggaatggta cctacagaag ccaggccagt
      241 ctccacaact cttgatttat gaggtctcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcag cagagtggag gctgaggatg
      361 ctggggttta ttactgcatg caagctcgag agtttccatt cactttcggc cccgggacca
      421 aactggacat caaacgag
//
LOCUS       KCVT01003343             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20416:15483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003343
VERSION     KCVT01003343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20416:15483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80868.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggtg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003344             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23725:14013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003344
VERSION     KCVT01003344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23725:14013"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80869.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgtggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003345             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12775:14856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003345
VERSION     KCVT01003345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12775:14856"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80870.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           85 t
ORIGIN      
        1 acagggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003346             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17090:18110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003346
VERSION     KCVT01003346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17090:18110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..328
                     /note="immunoglobulin light chain variable region"
     V_region        45..328
     V_segment       45..290
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <268..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80871.1"
                     /translation="CMQALDFPWTF"
     J_segment       291..328
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>331
                     /gene="IGKC"
BASE COUNT           79 a           80 c           95 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct ctcctgcagg
       61 tctagtcaga gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag
      121 aagccaggcc agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc
      181 ccagacaggt tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg
      241 gaggctgagg atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc
      301 ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003347             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18958:14821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003347
VERSION     KCVT01003347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18958:14821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80872.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          127 c          116 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtcc ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01003348             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20576:12435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003348
VERSION     KCVT01003348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20576:12435"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80873.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagtcac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003349             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18279:15704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003349
VERSION     KCVT01003349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18279:15704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80874.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          121 c          110 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01003350             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7538:6906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003350
VERSION     KCVT01003350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7538:6906"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..384
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80875.1"
                     /translation="CQQYSDFLLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           96 a          126 c          111 g           92 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggatcccaga taccgccgga aaaattgtca tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aacagccacc ctctcctgca gggccagtga
      181 gagtgttggc accttcttag cctggtacca acagaaacct gggcaggctc ccaagctcct
      241 tgtccatagt gctttcttca gggcccctgg catcccagac aggttcagtg gcagcgggtc
      301 taggacagag ttcactctca ccatcaacac cctggagcct gaagatgttg gagtttatca
      361 ctgtcagcag tatagtgact tcctgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003351             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16410:6098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003351
VERSION     KCVT01003351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16410:6098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    39..360
                     /note="immunoglobulin light chain variable region"
     V_region        39..360
     V_segment       39..323
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80876.1"
                     /translation="CQQDFDWPPTF"
     J_segment       326..360
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>363
                     /gene="IGKC"
BASE COUNT           83 a          110 c           95 g           75 t
ORIGIN      
        1 acatgggcct gctactctgg atcccagata ccaccggaga agttgtgatg acgcagtctc
       61 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      121 gtgttggcaa caccttaacc tggtaccagc acagacctgg gcaggctccc aagctcctcc
      181 tctatggtgc atccaccagg gccaccggca tcccagacag gttcgctgcc agtgggtctg
      241 gaacagactt tactctcacc atcagcagcc tggagcctga agatgttgga atttattact
      301 gtcagcagga ttttgactgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      361 gag
//
LOCUS       KCVT01003352             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22373:18470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003352
VERSION     KCVT01003352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22373:18470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80877.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          112 c          102 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acgttaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcagc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003353             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:4674:15210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003353
VERSION     KCVT01003353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:4674:15210"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80878.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggccttcat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003354             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:26984:16048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003354
VERSION     KCVT01003354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:26984:16048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80879.1"
                     /translation="CQQGYNFPFTF"
     J_segment       391..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          113 c          109 g          100 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccagg tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgtaggaga cacagtcacg atcacttgcc aggcgagtca
      181 aggcattggc aaaaatttaa attggtatca acagaaacca gggaaagccc ctaaactcct
      241 gatttatagg gcatccagtt tgcaaagtgg agttcactct cggtttagcg gcagtggatc
      301 cgggacggat ttctctctca ccatcagcag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttataatt tcccgttcac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003355             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10308:15488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003355
VERSION     KCVT01003355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10308:15488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80880.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          114 c          107 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt catcatcact tgcagagcca gtcacgatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatta gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003356             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11066:18928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003356
VERSION     KCVT01003356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11066:18928"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80881.1"
                     /translation="CQQYNDLLPLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          121 c          116 g           92 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggatcccaga taccgccgga gaaattgtaa tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aacagccacc ctctcctgca gggccagtga
      181 gagtgttggc agctacttag cctggtacca gcagaaacct gggcaggctc ccaagctcct
      241 tgtccatagt gcatacttca gggccactgg catcccagac aggttcagtg gcagcgggtc
      301 taggacagag ttcactctca ccattagcag cctggagcct gaagatgttg gagtttatta
      361 ctgtcagcag tataatgact tgcttccgct cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003357             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12891:1927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003357
VERSION     KCVT01003357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12891:1927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80882.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagggggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggggagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003358             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16021:20862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003358
VERSION     KCVT01003358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16021:20862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80883.1"
                     /translation="CMQAREFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          126 c          115 g          101 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggagg ggaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgctggggtt tattactgca tgcaagctcg agagtttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01003359             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7427:4557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003359
VERSION     KCVT01003359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7427:4557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80884.1"
                     /translation="CQQGYSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          119 c          107 g           97 t
ORIGIN      
        1 acatggggag tcattctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gcaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattggcaa tactttaaat tggtatcaac agaaaccggg gaaagcccct acactcctga
      241 tctatagggc atccggtttg caaagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttat ccgtacagtt ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01003360             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:6233:8255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003360
VERSION     KCVT01003360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6233:8255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80885.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          116 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc gggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01003361             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5281:6465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003361
VERSION     KCVT01003361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5281:6465"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80886.1"
                     /translation="CQQHDNSPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c          111 g           86 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagag
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaggccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gacaattccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003362             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15975:13287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003362
VERSION     KCVT01003362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15975:13287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80887.1"
                     /translation="CQQYDSDSLTF"
     J_segment       377..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          102 a          114 c          108 g           93 t
ORIGIN      
        1 atggggagac ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctaggac
       61 tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag tctccatcct
      121 ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgact caggacattc
      181 gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt
      241 acgcgtccac tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac
      361 agtatgacag tgattcgctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01003363             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17947:17354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003363
VERSION     KCVT01003363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17947:17354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80888.1"
                     /translation="CQQYNTLPLTF"
     J_segment       382..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          107 a          107 c          109 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtagttat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat actttaccgt tgacgttcgg ccaagggacc aaggtggaaa tcaaaggag
//
LOCUS       KCVT01003364             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17475:7625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003364
VERSION     KCVT01003364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17475:7625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80889.1"
                     /translation="CQQGNSNPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          109 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattaacag ttatttacat tggtatcagc agaaaccggg gaaaccccct aggctcctga
      241 tctattatac aaacagtttg gcaagtgggg tcccatcaag gttcagcggc cgtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtaac cctccgacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003365             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12448:19805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003365
VERSION     KCVT01003365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12448:19805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80890.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccagtttg gaaagtgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01003366             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14315:11111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003366
VERSION     KCVT01003366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14315:11111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80891.1"
                     /translation="CMQALEFPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          117 c          120 g          105 t
ORIGIN      
        1 acatggggga cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagcc
      181 tcttggatag tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca tacgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcag tagagtggag gctgaggatg
      361 ttgggattta ttactgcatg caagctctag agtttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01003367             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20943:10212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003367
VERSION     KCVT01003367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20943:10212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80892.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          105 a          125 c          120 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcaac agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01003368             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12395:16104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003368
VERSION     KCVT01003368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12395:16104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80893.1"
                     /translation="CIQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atctagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa gtcagcagag tggaggctga
      361 ggatgttggg gtttattact gcattcaagc tctagaattt ccgtggacgt tcggcccagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003369             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20628:2814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003369
VERSION     KCVT01003369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20628:2814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80894.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc actcttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttacgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa gatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003370             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9565:15399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003370
VERSION     KCVT01003370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9565:15399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80895.1"
                     /translation="CLQYKSYPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           97 a          116 c          110 g          102 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgcccgatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgctt ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 gggtcttagt agttctttac attggtttca gcagaaacca gggaaagccc ctaggctcct
      241 gatctatgct gcatccagtt tggcaggtgg ggtcccatca aggttcagcg gcactggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg ctacttatta
      361 ctgtctacag tataaaagtt acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003371             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11128:4552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003371
VERSION     KCVT01003371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11128:4552"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80896.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagggtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003372             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12420:19591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003372
VERSION     KCVT01003372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12420:19591"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80897.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga attcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003373             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13122:20106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003373
VERSION     KCVT01003373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13122:20106"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80898.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003374             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18884:10140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003374
VERSION     KCVT01003374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18884:10140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80899.1"
                     /translation="CLQFKTFPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          117 c          105 g          101 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatctc ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctaag ctcctcatct
      241 atgctgcatc cactttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagacttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtttaa aactttcccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003375             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10888:5652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003375
VERSION     KCVT01003375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10888:5652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80900.1"
                     /translation="CQQHNSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          117 c          105 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcgt
      181 tagcaattat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc attttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgctactt attactgtca
      361 acagcataat agttatcctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003376             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24202:15575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003376
VERSION     KCVT01003376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24202:15575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80901.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          108 c          109 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct ctgggggaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003377             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21905:13522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003377
VERSION     KCVT01003377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21905:13522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80902.1"
                     /translation="CQQDFGWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          121 c          116 g           89 t
ORIGIN      
        1 acatggggga aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagactgttg gcagcgcctt agcctggtac cagcagaaac ctgggcagac tcacaaactc
      241 ctcatttatg gtgcatccag cagggccacc ggcatcccag acaggttcag tggcagtggg
      301 tctggaacag agttcactct caccatcagt agtccggagc ctgcggatgt tggactttat
      361 tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01003378             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13341:15844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003378
VERSION     KCVT01003378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13341:15844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..349
                     /note="immunoglobulin light chain variable region"
     V_region        28..349
     V_segment       28..302
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80903.1"
                     /translation="CQQHNNYSPTF"
     J_segment       315..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           92 a           96 c           86 g           78 t
ORIGIN      
        1 acatgggggc tcccaggtgc cagatgtgac atccagatga cccagtctcc accctccctg
       61 tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg cattagcaat
      121 gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat ctattacgca
      181 tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc
      241 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagcat
      301 aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003379             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:3605:18795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003379
VERSION     KCVT01003379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3605:18795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80904.1"
                     /translation="CQHSYDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          116 c          103 g           97 t
ORIGIN      
        1 acatgggagt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagcccctg agctcctgat
      241 ttatgttaca tccactttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcatagt tatgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003380             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20284:17553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003380
VERSION     KCVT01003380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20284:17553"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80905.1"
                     /translation="CQQNSNRPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          122 c          117 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaattgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agtagtttag cctggtacca gcagagacct gggcagcctc ccaggctcct
      241 catctatggt gcgtccagca gggccactgg catcccagac agattcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagccc gaagatgttg cagtttattt
      361 ttgtcagcag aatagtaatc ggccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003381             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16077:15103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003381
VERSION     KCVT01003381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16077:15103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..453
                     /note="immunoglobulin light chain variable region"
     V_region        117..453
     V_segment       117..415
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <393..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80906.1"
                     /translation="CLQDIQLPLTF"
     J_segment       416..453
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>456
                     /gene="IGKC"
BASE COUNT           94 a          127 c          127 g          108 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggatc aggactcctc aggtcacctt ctcacaatga
       61 ggctccctgc tcagctcctg gggctgctgg tgctctggct ccctgggacc agtggggata
      121 ttatgatgac tcagactcca ctctccctgt ccgtcacccc tggagagccg gcctccatct
      181 cctgcaggtc tagtcagagc ctcctgcata ggaatgggta cacctatttg ttttggtacc
      241 tgcagaagcc aggccagtct ccacagctcc tgatctattt cggttccaac cgggcctctg
      301 gagtcccaga caggttcagt gccagtgggt caggcactga tttcacactg aaaatcagcc
      361 gggtggaggc tgaggatgtt ggggtttatt actgcttgca agatatacaa cttccgctca
      421 ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01003382             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14976:16621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003382
VERSION     KCVT01003382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14976:16621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80907.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc actggggaca ttgtgctgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagaac
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga gcctgaggat
      361 gttggggttt attactgcat gcaagctcta gaatttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01003383             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17624:11675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003383
VERSION     KCVT01003383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17624:11675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80908.1"
                     /translation="CQQYNSLPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          109 c          108 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagttat tatttaaatt ggtatcaaca gaaaccgggg aaagccccta aggtcctgat
      241 ctattacaca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa gttattactg
      361 tcaacaatat aatagtttac cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003384             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18889:11602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003384
VERSION     KCVT01003384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18889:11602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80909.1"
                     /translation="CMQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactccc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatgttgag gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gttttatttc tgcatgcaga gtctggagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01003385             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:26403:20291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003385
VERSION     KCVT01003385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26403:20291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80910.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           90 a          122 c          118 g          110 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtctgag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01003386             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17336:16915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003386
VERSION     KCVT01003386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17336:16915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..277
                     /note="immunoglobulin light chain variable region"
     V_region        9..277
     V_segment       9..235
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80911.1"
                     /translation="CQQYDSDSLTF"
     J_segment       240..277
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           73 a           68 c           75 g           64 t
ORIGIN      
        1 acatggggag tcaccatcac ttgtcgggcg actcaggaca ttcgcagtta tttagcgtgg
       61 tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc cactttggaa
      121 agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc
      181 agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtatga cagtgattcg
      241 ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003387             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14556:16329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003387
VERSION     KCVT01003387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14556:16329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80912.1"
                     /translation="CLQFKTYPNSF"
     J_segment       382..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           96 a          117 c          106 g          101 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatctc ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctcag ctcctcatct
      241 atgctgcatc cagtttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattctc tctcaccatc accagcctgc agcctgaaga ttttgcaact tatttctgtc
      361 tgcagtttaa aacttacccg aacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003388             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17946:18488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003388
VERSION     KCVT01003388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17946:18488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80913.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcaaca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01003389             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19512:13305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003389
VERSION     KCVT01003389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19512:13305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80914.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctcccc gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003390             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13333:16446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003390
VERSION     KCVT01003390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13333:16446"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80915.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003391             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12393:13294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003391
VERSION     KCVT01003391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12393:13294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80916.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          120 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcggagtg gaggctgagg
      361 atgttggggt ctattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003392             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16238:6199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003392
VERSION     KCVT01003392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16238:6199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80917.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01003393             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10126:13819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003393
VERSION     KCVT01003393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10126:13819"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80918.1"
                     /translation="CQQYTSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          121 c          105 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga ctgaggacgt
      181 tagcagtcat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttttgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgaggac tttgtaactt atcactgtca
      361 acagtacact agtttccccc tcaccttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003394             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17154:13467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003394
VERSION     KCVT01003394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17154:13467"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80919.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggagactgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01003395             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24063:9587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003395
VERSION     KCVT01003395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24063:9587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..363
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80920.1"
                     /translation="CLQGYNIPYNF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          109 c          109 g           97 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctccttctgc tctggctccc aggtgccaga tgtgacatcc agttgaccca gtctccatct
      121 tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 agcgattatt taagttggta tcagcagaaa ccaggaaaag ctcctaagcg cctgatctat
      241 gctgtgtcca gtttggaagg tggggtccca tcaagattca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcgactta ttactgtcta
      361 cagggttata atatcccgta caattttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01003396             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25475:4513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003396
VERSION     KCVT01003396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25475:4513"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80921.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag tcggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ctcagtggca gtgggtcaga cactgatttc acactgaaaa taagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003397             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:4192:12247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003397
VERSION     KCVT01003397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:4192:12247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80922.1"
                     /translation="CMQGLQTPYTF"
     J_segment       398..434
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgcct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcacc cttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgaa tagtaatgga tacagctatt tgagttggta cctgcagagg ccaggccagt
      241 ctccacatct gctgatctat tatggctcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgaaaatcac cagggtggag gctgacgacg
      361 taggggttta ttactgcatg caaggtctac aaactccgta cacttttggc cagggaccaa
      421 agtggagatc aaacgag
//
LOCUS       KCVT01003398             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11924:12860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003398
VERSION     KCVT01003398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11924:12860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80923.1"
                     /translation="CLQFKTCPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          117 c          105 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa acttgcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003399             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8022:9295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003399
VERSION     KCVT01003399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8022:9295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80924.1"
                     /translation="CQQGYGFPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          119 c          106 g          102 t
ORIGIN      
        1 acatggggga ggagtcagtc tcagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctccttgggc tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacgcag
      121 tctccatcct ccctgtccgc atctgtagga gacacagtcg cgatcacttg cctggcgagt
      181 caaggcattg gcaataattt aaattggtat cagcagaaac cagggaaagc ccctaaactc
      241 ctgatctata cggcatccaa tttacatggt gggattccct ctcggttcag cggcagtgga
      301 tctgggacgg atttcactct caccatcaac agcctgcagc ctgaagattt tgccacttat
      361 tactgtcaac agggttatgg ttttccattc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01003400             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19053:14120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003400
VERSION     KCVT01003400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19053:14120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80925.1"
                     /translation="CQQGYSYPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          119 c          107 g           96 t
ORIGIN      
        1 acatgggagt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg caggagacac agtcaccatc acttgccagg cgagtcaagg
      181 cattggcaat actttaaatt ggtatcaaca gaaaccgggg aaagccccta cactcctgat
      241 ctatagggca tccggtttgc aaagtgggac tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagttatc cgtacagttt tggccagggg accaaactgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003401             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20625:10675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003401
VERSION     KCVT01003401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20625:10675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80926.1"
                     /translation="CQQYFRFPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          111 c          106 g          102 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagcca
      181 ggacattagt aattatttaa attggtatca gcagaaaccg gggaaagccc ctaaactcct
      241 gatcttttat gcaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacaaaa ttcactctct ccatcagcag cctgcaacct gaagattttg ctacttatca
      361 ttgtcaacag tattttaggt ttccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003402             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15695:18175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003402
VERSION     KCVT01003402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15695:18175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80927.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          122 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003403             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13151:17802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003403
VERSION     KCVT01003403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13151:17802"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80928.1"
                     /translation="CQQYDSDPFTF"
     J_segment       408..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          108 a          122 c          119 g           97 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgcg tctgtaggag acagagtcac
      181 catcacttgt cgggcgagtc agggcattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtatgacagt gacccgttca ctttcggtgg
      421 agggaccaag gtagagatca aacgag
//
LOCUS       KCVT01003404             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17781:12531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003404
VERSION     KCVT01003404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17781:12531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..348
                     /note="immunoglobulin light chain variable region"
     V_region        9..348
     V_segment       9..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80929.1"
                     /translation="CMQALEFPLTF"
     J_segment       312..348
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           79 a           88 c           99 g           85 t
ORIGIN      
        1 acatggggga cattgtgctg acccagactc cactctccct gcccgtcacc cttggagagc
       61 cggcctccat ctcctgcagg tctagtcaga gcctcttgga tagtggggat ggaaacacct
      121 atttggattg gtacctgcag aagccaggcc agtctccaca gctcttgatt tatgaggttt
      181 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      241 cactgaaaat taacagagtg gaggctgagg atgttggggt ttattactgc atgcaagctc
      301 tagagtttcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003405             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18943:1990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003405
VERSION     KCVT01003405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18943:1990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80930.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 tgtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01003406             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19831:18247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003406
VERSION     KCVT01003406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19831:18247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80931.1"
                     /translation="CLQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc ttgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003407             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13873:15341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003407
VERSION     KCVT01003407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13873:15341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..243
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80932.1"
                     /translation="CQQYDSDSLTF"
     J_segment       248..285
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           75 a           70 c           80 g           63 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gtcgggcgac tcaggacatt cgcagttatt
       61 tagcgtggta tcagcagaga ccagggaaag ccccgaggcc cttgatctat tacgcgtcca
      121 ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcaaccta ttactgtcaa cagtatgaca
      241 gtgattcgct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003408             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9895:6408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003408
VERSION     KCVT01003408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9895:6408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..391
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80933.1"
                     /translation="CQQHNGYPPTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          111 a          124 c          111 g           95 t
ORIGIN      
        1 acatgggggg tcacacttca tgtaggagtc agaaccactc aggacacagc atggacatga
       61 gggtccccgc tcagctcctg gggctcctgc tgctctggct cccaggtgcc agatgtgaca
      121 tccagatgac ccagtctcca tcctccctgt ctgcatctgt aggagacaca gtcaccatca
      181 cttgtcgggc aagtcagggc attacgaatg atttagcctg gtatcaacag aaaccaggta
      241 aagccccgaa gcccctgatc tattacgcat ccaatttgga aagtggggtc ccatcaaggt
      301 tcagcggcag tggatctggg acagatttca ctctcaccat cagcagcctg cagcctgaag
      361 attttgcaac ttattattgt caacagcata atggctaccc tccgacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01003409             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23998:10462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003409
VERSION     KCVT01003409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23998:10462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80934.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagcgc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003410             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13438:11054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003410
VERSION     KCVT01003410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13438:11054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80935.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          118 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagccta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003411             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17797:7281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003411
VERSION     KCVT01003411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17797:7281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80936.1"
                     /translation="CQQHDNSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctctct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtgt
      181 tagcgactgg ttggcctggt atcaacagag accagggaaa gcccctaaac tcctgatcta
      241 tagggcgtcc aatttggata caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgctacat attactgtca
      361 acagcatgat aattcccctc cgacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003412             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18939:11840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003412
VERSION     KCVT01003412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18939:11840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80937.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003413             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19976:6457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003413
VERSION     KCVT01003413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19976:6457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80938.1"
                     /translation="CQQGYSFPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           94 a          122 c          105 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcagtagt ttaagctggt atcagcagaa accagggaaa gcccctaacc tcctgatctt
      241 tagggcatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctcca gcctgaagat tttgccactt attactgtca
      361 acagggttat agtttcccct tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003414             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:3170:17881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003414
VERSION     KCVT01003414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3170:17881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80939.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          126 c          111 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg aaaaattgtc atgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgctttcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003415             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18133:7091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003415
VERSION     KCVT01003415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18133:7091"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80940.1"
                     /translation="CMQSTKDPLTF"
     J_segment       401..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           98 a          124 c          110 g          107 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tccagtggcg atattttgct gacccagact
      121 ccactctcgc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcat
      181 agccttctgc atagtaatgg atacacctat ttgcattggt acctgcagaa gccaggccag
      241 tctccacggc tcctgatcta taaagttacc aatcgggaat ctggggtccc agacaggttc
      301 agcggcagtg ggtcaggcat agatttcaca ctggaaatca gcagggtgga gcctgaggat
      361 gttggtattt attactgcat gcaaagtaca aaagatcccc tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01003416             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6824:17364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003416
VERSION     KCVT01003416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6824:17364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80941.1"
                     /translation="CLQYKSFPYTF"
     J_segment       388..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          110 a          116 c           97 g           98 t
ORIGIN      
        1 acatggggtc agacacagtc aggacacagc atggacatga gggcccccgc tcatctccta
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac tcagtctcca
      121 tcttccctgt ctgcatctgt gggagacact gtcaccatca cttgccggac aagtcaaggt
      181 ataaccaatt atttacattg gtttcagcag aaaccaggga gaacccctaa gctcctgatc
      241 tatgaaacat ccagtttgac aagtggggtc ccatcaaggt tcagcggcag tgcatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 ctacagtata aaagtttccc gtataccttt ggccagggga ccaaactgga gatcaaacga
      421 g
//
LOCUS       KCVT01003417             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9783:2395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003417
VERSION     KCVT01003417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9783:2395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80942.1"
                     /translation="CQQVYGNPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          118 c          107 g          101 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtcc
      121 ccatctgcct tgtctgcatc tgggggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata gttatttagc gtggtatcag cagaaaccag gtaaagcccc taagctcctg
      241 atctatggta catccagatt gcaaagcggg attccctctc ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattctgc cgcttattac
      361 tgtcaacagg tttatggtaa cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003418             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12340:18319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003418
VERSION     KCVT01003418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12340:18319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80943.1"
                     /translation="CQQYNSGPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aagactttgc aacttattac
      361 tgtcaacagt ataacagtgg cccattcact tttggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003419             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19528:4531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003419
VERSION     KCVT01003419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19528:4531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80944.1"
                     /translation="CMQGTQLLTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          117 c          114 g           97 t
ORIGIN      
        1 atggggactg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg ggatgttgtg atgactcagt ctccactctc
      121 cctgcccatc acccctggac aaccggcctc catctcctgc aggtctagtc aaagccttct
      181 acacactgat gggaaaacct acttgaattg gtatcagcag aagccaggcc aacctccaag
      241 gcgcctaatt tatcaggttt ctaaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gagactgagg atgttggagt
      361 ttattactgc atgcaaggta cacagcttct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003420             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23103:3092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003420
VERSION     KCVT01003420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23103:3092"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80945.1"
                     /translation="CQQYNSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          111 c          113 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccattaat tgtcgggcga gtcaggacat
      181 tagcagttat ttagcgtggt atcggcagag gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttggaactt attactgtca
      361 acagtataac agtgactcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003421             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16924:18870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003421
VERSION     KCVT01003421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16924:18870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80946.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          111 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgt agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga atttactctc accatcagaa gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003422             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10543:17861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003422
VERSION     KCVT01003422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10543:17861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80947.1"
                     /translation="CIQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          121 c          118 g          109 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccaccgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cttctcctgt aggtctagtc
      181 acagcctctt ggatagtgag gatggaaata tccatttgga ttggtatctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggtttagtgg cagtgggtca gacactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttactac tgcatacaat ctctagagtt tccttggacg ttcggccagg
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01003423             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:25868:10255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003423
VERSION     KCVT01003423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25868:10255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..331
                     /note="immunoglobulin light chain variable region"
     V_region        131..331
     V_segment       131..293
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80948.1"
                     /translation="CLQPLEFPWTF"
     J_segment       294..331
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           73 a           90 c           91 g           80 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga
      181 gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga
      241 gtggaggctg aggatgttgg ggtttattac tgcttgcaac ctctagagtt tccgtggacg
      301 ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01003424             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21845:10683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003424
VERSION     KCVT01003424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21845:10683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80949.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01003425             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10165:10403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003425
VERSION     KCVT01003425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10165:10403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80950.1"
                     /translation="CQQYHSAPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          115 c          121 g          104 t
ORIGIN      
        1 acatggggga gctacaacag gcaggcaggg gcagcaagat ggtgtcacag acccaagtct
       61 tcatttccct gttgctctgg atctctggtg cctgtgggga cattgtgatg acccagtctc
      121 cagactccct ggctgtgtct ctgggcgaga gggtcaccat caactgcaag tccagccaga
      181 gtcttttata ctactccaac aataagaact acttagcctg gtaccagcag aaaccgggac
      241 aggctcctaa tctgctcatt tattgggcat ctacccggga atccggggtc cctaaccgat
      301 tcagtggcag tggatctggg tcagatttca ctctcacgat cagtggcctg caggctgaag
      361 atgtggcagt gtatttctgt cagcagtatc atagcgctcc gctcactttc ggtggaggga
      421 ccaacgtgga gatcaaacga g
//
LOCUS       KCVT01003426             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10395:12420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003426
VERSION     KCVT01003426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10395:12420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80951.1"
                     /translation="CQQYDSDAFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacgcg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01003427             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12791:21424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003427
VERSION     KCVT01003427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12791:21424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80952.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagaccggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003428             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17654:16713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003428
VERSION     KCVT01003428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17654:16713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80953.1"
                     /translation="CQQYNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gacattacca atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagt ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01003429             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13114:19315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003429
VERSION     KCVT01003429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13114:19315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80954.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          103 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaagtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagttcc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003430             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:14193:14708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003430
VERSION     KCVT01003430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14193:14708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80955.1"
                     /translation="CQQYNSDWRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac tggcgcactt tcggtggagg gaccaatgtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003431             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22863:4825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003431
VERSION     KCVT01003431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22863:4825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80956.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctactc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003432             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19057:10659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003432
VERSION     KCVT01003432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19057:10659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80957.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgagcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003433             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12211:4356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003433
VERSION     KCVT01003433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12211:4356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80958.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagtcac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003434             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13448:12161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003434
VERSION     KCVT01003434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13448:12161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80959.1"
                     /translation="CQQYDSFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          116 c          100 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatac aaatcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatagtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01003435             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8759:6448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003435
VERSION     KCVT01003435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8759:6448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80960.1"
                     /translation="CQQGYNTPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          119 c          118 g           89 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcg tccctgtctg catctgtagg agacaaagtc accatcactt gccgagccag
      181 tcagggtatt agcggctggt tagcctggta tcagcagaaa ccagggaaag cccctagact
      241 cctgatctat aaggcgtcca ctttggcaag tggggtccca tcaaccttca gcggcagtgg
      301 atctggggcg gattacactc tcaccatcag caggctgcag cctgaagatt ttgcaactta
      361 ttattgtcaa cagggttaca ataccccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01003436             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8950:14831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003436
VERSION     KCVT01003436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8950:14831"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80961.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          119 c          116 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcagtag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003437             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13911:11929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003437
VERSION     KCVT01003437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13911:11929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80962.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtcaagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttgcact ggtacttgaa gaagccaggc
      241 cagtctccac aggtcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003438             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23818:5220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003438
VERSION     KCVT01003438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23818:5220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80963.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggtctgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003439             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19302:10807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003439
VERSION     KCVT01003439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19302:10807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80964.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag cagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003440             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:28051:8638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003440
VERSION     KCVT01003440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:28051:8638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..319
                     /note="immunoglobulin light chain variable region"
     V_region        119..319
     V_segment       119..282
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80965.1"
                     /translation="CMQALEFPWTF"
     J_segment       283..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           73 a           81 c           89 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagacgc
      121 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      241 gatgttggta tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003441             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9800:5051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003441
VERSION     KCVT01003441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9800:5051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80966.1"
                     /translation="CQHSHGSPITF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           98 t
ORIGIN      
        1 acatgggggg agtctgtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgtttac aactatttac attggtatca gcagaaacca gggaaagccc ctaaggtcct
      241 gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggactgat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003442             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20965:10847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003442
VERSION     KCVT01003442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20965:10847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80967.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtcaagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgca ctggtacttg aagaagccag
      241 gccagtctcc acagctctta atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003443             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14551:16668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003443
VERSION     KCVT01003443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14551:16668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80968.1"
                     /translation="CQQYESDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          113 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccgtcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgaa agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003444             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12955:14696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003444
VERSION     KCVT01003444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12955:14696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80969.1"
                     /translation="CQNGYGIPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          125 c          107 g           94 t
ORIGIN      
        1 acatggggga gtcagtccca gtcaggacac agcatggaca tgagggcccc cactcagctc
       61 ctggggttcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcca ggcgagtcag
      181 ggcattgcca atgatttagc ctggtatcag cagaaaccgg gaaacgcccc taagctcctt
      241 atctctaggg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcagaatg gttatggtat cccattcact ttcggccccg ggaccaaact ggacatcaaa
      421 cgag
//
LOCUS       KCVT01003445             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16868:8158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003445
VERSION     KCVT01003445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16868:8158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80970.1"
                     /translation="CMQGLEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaga tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactaaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003446             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17549:11897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003446
VERSION     KCVT01003446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17549:11897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80971.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          120 c          121 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttccaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcg cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003447             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23236:10319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003447
VERSION     KCVT01003447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23236:10319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80972.1"
                     /translation="CQQFNNLPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct ggaggagaca gcgtcaccat cagttgccgg gcaagtcagg
      181 acattagcac ttatttaaat tggtttcagc aaaaaccggg gaaagcccct aagctcctga
      241 tctatgatgg aaaccgtttg gagactgggg tcccatcaag gttcagcggc agtggatccg
      301 ggacagaatt cagtctcacc atcaccagcc tgcaacctga agattttgca acttattact
      361 gtcaacagtt taataattta cctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003448             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21565:3380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003448
VERSION     KCVT01003448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21565:3380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..372
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80973.1"
                     /translation="CQQDYSYPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          113 c          115 g           93 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacatgag ggtccccgtg cagctcctgg
       61 ggctcctgtt gctctggctc caaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgtg ggagacagag tcaccgtcac ttgccgggcg agtcaaggca
      181 ttaacaagga gttaatctgg tatcagaaga aaccagggaa agcccctaca ctcctgatct
      241 atgctgcctc caccttgcag acgggggtct catctcggtt cagtggcagt ggagttggga
      301 cagacttcac tctcaccatc agcagcctgc agcctgaaga tgttgctact tatttctgtc
      361 aacaggatta tagttatccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01003449             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21284:18297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003449
VERSION     KCVT01003449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21284:18297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80974.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactga
      181 ggatattcgc agttacttgg cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003450             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22998:6231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003450
VERSION     KCVT01003450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22998:6231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80975.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcactggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttattt
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 atgag
//
LOCUS       KCVT01003451             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:27535:7364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003451
VERSION     KCVT01003451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:27535:7364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80976.1"
                     /translation="CQQYNSLPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          108 c          110 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cagatattta aattggtatc agcagaaacc ggggaaagcc cctaagttcc
      241 tgatctatta tgtaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 attgtcaaca gtataatagt ttaccgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003452             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9775:12012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003452
VERSION     KCVT01003452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9775:12012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80977.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctcatgctct ggctccctgt atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc ggtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 tgatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003453             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19352:16910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003453
VERSION     KCVT01003453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19352:16910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80978.1"
                     /translation="CQQYNNLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          108 c          106 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacaata taataattta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003454             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18128:4067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003454
VERSION     KCVT01003454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18128:4067"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80979.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcaac agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01003455             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14499:15540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003455
VERSION     KCVT01003455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14499:15540"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80980.1"
                     /translation="CQQGYSYPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          116 c          112 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccctcctccc tgtccgcatc tgtaggagac gcagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca ataatttaaa ttggtttcag cagaaaccag ggaaagcccc taaactcctg
      241 atctataaga catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta cccgtggacg ttcggccaag gggccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003456             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17316:14272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003456
VERSION     KCVT01003456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17316:14272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80981.1"
                     /translation="CQQGYNTPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           91 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagttcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcgtccctg tctgcatctg taggagacaa agtcaccatc acttgccgag ccagtcaggg
      181 tattagcagc tggttagcct ggtatcagca aaaaccaggg aaagccccta gactcctgat
      241 ctataaggcg tccactttgg caagtggggt cccatcaacc ttcagcggca gtggatctgg
      301 gacggattac actctcacca tcagcaggct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagggt tacaataccc cgtggacgtt cggccaaggg accaaggtgg atatcaaacg
      421 ag
//
LOCUS       KCVT01003457             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15683:4789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003457
VERSION     KCVT01003457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15683:4789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80982.1"
                     /translation="CQQYNEYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gtataatgaa taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003458             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17537:14121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003458
VERSION     KCVT01003458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17537:14121"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80983.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttctttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003459             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11342:13556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003459
VERSION     KCVT01003459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11342:13556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80984.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          112 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctcctt ctcctgcagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaacatct atttgaattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca tattgaaaat caccagagtg gaggctgagg
      361 atgttggcgt ttattactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003460             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5029:9420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003460
VERSION     KCVT01003460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5029:9420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80985.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003461             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14773:11970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003461
VERSION     KCVT01003461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14773:11970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..366
                     /note="immunoglobulin light chain variable region"
     V_region        89..366
     V_segment       89..328
                     /gene="IGKV1-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80986.1"
                     /translation="CQKCDTVPWTF"
     J_segment       329..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           91 a           97 c           95 g           86 t
ORIGIN      
        1 acatggggag aagtctctct cagtccggac acagcatgga catgagggct tcagctcagc
       61 tcctgggact cctgttgctc tggctcccag gagacaaagt caccatcact tgccgggcga
      121 ctcagagcgt tggtaatagt ttagcctggt atcagcagaa accagggaaa gttcctaagc
      181 tcctgatcta tgctgcatcc actttagaat cagacgtccc atctcgattc agcggcagtg
      241 gatctgggac atatttcact ctcaccatca gcagcctgtt acctgaggat gttgcgactt
      301 attactgtca aaagtgtgac actgtcccgt ggacgttcgg ccaagggacc aaggtggaaa
      361 tcaaacgag
//
LOCUS       KCVT01003462             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14165:6560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003462
VERSION     KCVT01003462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14165:6560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..440
                     /note="immunoglobulin light chain variable region"
     V_region        98..440
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80987.1"
                     /translation="CMQALEFPPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          124 c          116 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattattgca tgcaagctct agagtttcct ccattcactt tcggccccgg
      421 gaccaaactg gagatcaaac gag
//
LOCUS       KCVT01003463             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24505:6239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003463
VERSION     KCVT01003463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24505:6239"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..386
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80988.1"
                     /translation="CQQYNDLLPFSF"
     J_segment       392..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g           94 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg acaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg cagctcctta gcctggtacc agcagaaacc tgggcaggct cccaagctcc
      241 ttgttcatag tgcatacttc agggccactg gcatcccaga gaggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accattagca gcctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtataatgac ttgcttccgt tcagttttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01003464             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21753:14545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003464
VERSION     KCVT01003464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21753:14545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80989.1"
                     /translation="CHQYNNLPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          115 c          100 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgc aaatcgtttg gaaactgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacccga agattttgca acttattact
      361 gtcaccagta taataattta ccactcactt tcggcggagg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01003465             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13876:6518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003465
VERSION     KCVT01003465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13876:6518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80990.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tttcctgcag gtcgagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcggtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003466             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21965:11697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003466
VERSION     KCVT01003466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21965:11697"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..400
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80991.1"
                     /translation="CMQNTEDPTF"
     J_segment       401..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>437
                     /gene="IGKC"
BASE COUNT          100 a          119 c          112 g          106 t
ORIGIN      
        1 acatgggggt gatcaggact cctcagttca tcttctcacg atgagactcc ctgctcagct
       61 cctcgggctg ttgatgctct gggtccctgg gtccagtggg gatattgtga tgacccagac
      121 tccactctcg ctgcccgtca cccctggaga gccggcctcc atctcctgca ggtctagtca
      181 aagccttctg catagtaatg gaaacaccta tttgcattgg tacctgcaga agccaggcca
      241 gtctccacgt ctcctgatct ataaagttac caatcgggaa tctggggtcc cagacaggtt
      301 cagtggcagt gggtcaggca cagatttcac actgaaaatc agcagggtgg agcctgaaga
      361 tgttggtgtt tattattgca tgcaaaatac agaagatccc actttcggcc ccgggaccaa
      421 actggatatc atacgag
//
LOCUS       KCVT01003467             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18445:13304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003467
VERSION     KCVT01003467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18445:13304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..284
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80992.1"
                     /translation="CQQYDSDPFTF"
     J_segment       287..322
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           82 a           84 c           85 g           74 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc
       61 atcacttgtc gggcgagtca gggcattcgc agttatttgg cgtggtatca ccagaaacca
      121 gggaaagccc cgaagccctt gatctattac gcgtccactt tggaaagtgg ggtcccatca
      181 aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag cctgcagcct
      241 gaagattttg caacttatta ctgtcaacag tatgacagtg acccgttcac tttcggtgga
      301 gggaccaagg tagagatcaa acgag
//
LOCUS       KCVT01003468             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7803:20185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003468
VERSION     KCVT01003468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7803:20185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80993.1"
                     /translation="CQQHDNFPYIF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          116 c          105 g           93 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 aacatattag cgactggttg gcctggtatc aacagaaacc agggaaagcc cctaagctcc
      241 tgatctatcg ggcatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gctttcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgataat ttcccgtaca tttttgacca ggggaccaaa ctggagatca
      421 aacgag
//
LOCUS       KCVT01003469             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7150:17877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003469
VERSION     KCVT01003469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7150:17877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80994.1"
                     /translation="CQQYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agattacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01003470             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19133:7605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003470
VERSION     KCVT01003470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19133:7605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80995.1"
                     /translation="CQQGYSYPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccctcctccc tgtccgcatc tataggagac gcaatcacga tcacttgcca ggcgagtcaa
      181 ggcattggca ataatttaaa ttggtttcag cagaaaccag ggaaagcccc taaacccctg
      241 atctataaga catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcaggctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta cccgtggacg ttcggccaag gggccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003471             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24395:19755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003471
VERSION     KCVT01003471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24395:19755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80996.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccacatgacc cagtctccat
      121 cctccctgtc tgcgtctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01003472             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11883:9358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003472
VERSION     KCVT01003472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11883:9358"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..364
                     /note="immunoglobulin light chain variable region"
     V_region        88..364
     V_segment       88..322
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80997.1"
                     /translation="CQQYDSDSLTF"
     J_segment       327..364
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           93 a           97 c           99 g           78 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagtc accatcactt gtcgggcgac
      121 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc
      181 cttgatctat tacgcgtcca cttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc aacctgcagc ctgaagattt tgcaacttat
      301 tactgtcaac aatatgacag tgattcgctc actttcggtg gagggaccaa ggtggagatc
      361 aaacgag
//
LOCUS       KCVT01003473             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12903:5763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003473
VERSION     KCVT01003473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12903:5763"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80998.1"
                     /translation="CQQYSDFLLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           96 a          126 c          112 g           91 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggatcccaga taccgccgga gaaattgtca tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aacagccacc ctctcctgca gggccagtga
      181 gagtgttggc accttcttag cctggtacca acagaaacct gggcaggctc ccaaactcct
      241 tgtccatagt gcattcttca gggcccctgg catcccagac aggttcagtg gcagcgggtc
      301 tgggacagag ttcactctca ccatcaacac cctggagcct gaagatgttg gagtttatca
      361 ctgtcagcag tatagtgact tcctgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003474             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24222:18237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003474
VERSION     KCVT01003474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24222:18237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV80999.1"
                     /translation="CQQYDSDPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           92 t
ORIGIN      
        1 acatgggggc cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagtcccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgctcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01003475             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5213:18244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003475
VERSION     KCVT01003475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5213:18244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81000.1"
                     /translation="CQHSYDTPYTF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          104 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtgcga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct gagctcctga
      241 tttatgttac atccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatgttgca acttattact
      361 gtcagcatag ttatgatacc ccctacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003476             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13950:6082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003476
VERSION     KCVT01003476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13950:6082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81001.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgct gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003477             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14023:15021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003477
VERSION     KCVT01003477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14023:15021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..439
                     /note="immunoglobulin light chain variable region"
     V_region        99..439
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81002.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat tagcagagtg gaggctgagg
      361 atgttggggt ttttttactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003478             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20736:9336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003478
VERSION     KCVT01003478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20736:9336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81003.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          124 c          114 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttccta gcctggtacc agcagaaacc tgggcaggct cccaagctcc
      241 ttgtccatag tgcattcttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003479             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25419:8255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003479
VERSION     KCVT01003479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25419:8255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81004.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gtatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccagtttg gaaagtgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01003480             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18837:9907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003480
VERSION     KCVT01003480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18837:9907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81005.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          110 c          103 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 ttacagttat ttgaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003481             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18047:7992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003481
VERSION     KCVT01003481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18047:7992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81006.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003482             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18527:4189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003482
VERSION     KCVT01003482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18527:4189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81007.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003483             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12498:15447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003483
VERSION     KCVT01003483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12498:15447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81008.1"
                     /translation="CQQHNTYPLTF"
     J_segment       388..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          118 c          103 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gacattagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atgtattacg catccaattt ggaaaatggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aagttattac
      361 tgtcaacagc ataatactta cccattgact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003484             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19082:11026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003484
VERSION     KCVT01003484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19082:11026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81009.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagaga cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca aactgaaaat cagcagactg gaggctgagg
      361 atgttgggct ttattactgc atgcaagctc tagagtttcc gtggacgttc ggcccaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003485             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10946:13999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003485
VERSION     KCVT01003485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10946:13999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81010.1"
                     /translation="CQQYFSTPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           96 a          127 c          110 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccacgc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agagctggta gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcaccctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagtac cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01003486             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17032:11339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003486
VERSION     KCVT01003486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17032:11339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81011.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           85 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag caaaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003487             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23114:13554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003487
VERSION     KCVT01003487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23114:13554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81012.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003488             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10462:14566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003488
VERSION     KCVT01003488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10462:14566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81013.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tgactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003489             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12146:18549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003489
VERSION     KCVT01003489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12146:18549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81014.1"
                     /translation="CQQYNTLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          111 c          107 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctgggctcct gctgctctgg ctcccaggtg ccagatgtga cactcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc aaaaaccggg gaaagcccct aagctcctga
      241 tctactatac aaaccgtttg gaaagagggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaaactga ggattttgca acttattatt
      361 gtcaacagta taatacttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003490             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:20172:6331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003490
VERSION     KCVT01003490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20172:6331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81015.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc gctttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003491             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16834:9986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003491
VERSION     KCVT01003491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16834:9986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..446
                     /note="immunoglobulin light chain variable region"
     V_region        125..446
     V_segment       125..408
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81016.1"
                     /translation="CQQGSPFPWTF"
     J_segment       409..446
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>449
                     /gene="IGKC"
BASE COUNT          113 a          117 c          116 g          103 t
ORIGIN      
        1 acatggggag aggctctttc tctgggatgt ggcatgagca aaactgacaa gtcaaggcag
       61 gaagatgttg tctccatcac aactcattgg gtttctgctg ctctgggttc cagcctccaa
      121 gggtgaaatt gtgctgactc agtctccagc ctttcggtct gtgactctaa aggagaaagt
      181 caccatcacc tgccaggcca gtcagagcat tggtaatagc ttacactggt accagcagaa
      241 accggatcag tctccaaagc tcctcatcaa atatgcttcc cagtccatct caggggtccc
      301 ctcaaggttc agtggcagtg gatctgggac agatttcacc ctcaccatca acagcctgga
      361 agctgaagat gctgcgacgt attactgtca gcagggaagt cctttcccgt ggacgttcgg
      421 ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003492             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13705:10125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003492
VERSION     KCVT01003492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13705:10125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..335
                     /note="immunoglobulin light chain variable region"
     V_region        7..335
     V_segment       7..298
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <275..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81017.1"
                     /translation="CMQSLEFPWTF"
     J_segment       299..335
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>338
                     /gene="IGKC"
BASE COUNT           74 a           85 c           93 g           86 t
ORIGIN      
        1 acatgggacc cagactccac tctccctgcc cgtcaccctt ggggagccgg cctccttctc
       61 ctgtaggtct agtcagagcc tcttggatgt tgaggatgga aacacctatt tggacttgta
      121 cctgcagaag ccaggccagt ctccacagct cttgatttat gaggtttcca accgggcctc
      181 tggagtccca gacaggttca gtggcagtgg gtctgacact gatttcacac tgaaaatcag
      241 tagagtggag gctgaggatg ttgggtttta tttctgcatg caaagtctgg agtttccttg
      301 gacgttcggc caagggacca agttggaaat caaacgag
//
LOCUS       KCVT01003493             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19752:10632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003493
VERSION     KCVT01003493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19752:10632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81018.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           94 a          117 c          124 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 gtactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct gggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggc acctgcagag gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc tatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctt ggacgttcgg ccaagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01003494             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15475:19024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003494
VERSION     KCVT01003494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15475:19024"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81019.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          119 c          117 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gagatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcagtag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003495             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17628:16432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003495
VERSION     KCVT01003495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17628:16432"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81020.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac caacaaaaac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt tgcagtctat
      361 ttttgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01003496             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25375:11828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003496
VERSION     KCVT01003496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25375:11828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81021.1"
                     /translation="CMQGLEYPYSF"
     J_segment       402..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctccctgga tccagtgggg atattgtgat gacccagact
      121 ccactctccc tgccagtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgcgga tggaaaaacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agcccttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ttagagtatc cgtacagttt tggccagggg
      421 accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01003497             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9501:4620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003497
VERSION     KCVT01003497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9501:4620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81022.1"
                     /translation="CQQYNSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          112 c          111 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtcaatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003498             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19055:11626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003498
VERSION     KCVT01003498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19055:11626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81023.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          127 c          111 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg agagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctttgg tacatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctcgaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003499             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:11408:4080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003499
VERSION     KCVT01003499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11408:4080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81024.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003500             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10427:10120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003500
VERSION     KCVT01003500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10427:10120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..281
                     /note="immunoglobulin light chain variable region"
     V_region        8..281
     V_segment       8..247
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81025.1"
                     /translation="CQQYNRLPRTF"
     J_segment       249..281
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>287
                     /gene="IGKC"
BASE COUNT           80 a           67 c           75 g           65 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg ccgggcaagt cagggcatta gtcaatattt
       61 aaattggtat cagcagaaac cggggaaagc ccctaggctc ctcatctatt atgtaaaccg
      121 tttagaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      181 caccatcagc agcctgcaac ctgaggattt tgcaacttat tactgtcagc agtataatcg
      241 tttacctcgg acgttcggcc aagggaccaa ggtggagatc agacgag
//
LOCUS       KCVT01003501             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10895:14667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003501
VERSION     KCVT01003501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10895:14667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81026.1"
                     /translation="CQQSYRYPLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          102 a          117 c          110 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaac aactatttac actggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatgtatctt gcatccactt tgcagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctcg ccatcagcag cctgcagcct gaagatgctg caacttatta
      361 ctgtcagcag agttatcgtt atccgctcac tttcggtgga gggacccagg tggaaatcaa
      421 tcgag
//
LOCUS       KCVT01003502             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17235:17188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003502
VERSION     KCVT01003502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17235:17188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..347
                     /note="immunoglobulin light chain variable region"
     V_region        8..347
     V_segment       8..309
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <287..>319
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81027.1"
                     /translation="CMQALDFPWTF"
     J_segment       310..347
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>350
                     /gene="IGKC"
BASE COUNT           82 a           88 c           99 g           81 t
ORIGIN      
        1 acatggggac attgtgatga cccagactcc actctccctg cccgtcaccc ttggagagcc
       61 ggcctccatc tcctgtaggt ctagtcagag cctcttggat agtgaggatg gaaacaccta
      121 tttggaatgg tacctgcaga agccaggcca gtctccacaa ctcttgattt atgaagtttc
      181 cgaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac
      241 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct
      301 ggactttccg tggacgttcg gccaagggac caaggtggaa gtcaaacgag
//
LOCUS       KCVT01003503             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17530:10625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003503
VERSION     KCVT01003503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17530:10625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81028.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003504             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24563:14911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003504
VERSION     KCVT01003504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24563:14911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81029.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          124 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gttgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003505             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13164:9599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003505
VERSION     KCVT01003505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13164:9599"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81030.1"
                     /translation="CIQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atacaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003506             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:17495:18030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003506
VERSION     KCVT01003506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17495:18030"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81031.1"
                     /translation="CQQRNGYPYMISF"
     J_segment       394..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          102 a          110 c          116 g          102 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagtt gatacagtct
      121 ccatcctccc tgtctgcgtc tgtaggagac agagtcacca tcacttgtcg ggcaagtcag
      181 gacattagca gttatttagc ctggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctataggg cgtccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agtttattac
      361 tgtcaacagc ggaatggtta cccgtacatg attagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01003507             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6811:14430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003507
VERSION     KCVT01003507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6811:14430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81032.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003508             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12671:4713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003508
VERSION     KCVT01003508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12671:4713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81033.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctcctca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003509             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:11669:12101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003509
VERSION     KCVT01003509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11669:12101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81034.1"
                     /translation="CQHYDSDSLTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aaggccttga
      241 tctactacgc gtccactttg gaaagtgggg tcccatcaag gttcggcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacacta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaagc
      421 gag
//
LOCUS       KCVT01003510             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24332:20068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003510
VERSION     KCVT01003510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24332:20068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81035.1"
                     /translation="CQHSYTTPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          114 c          105 g          103 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg ctagttataa
      181 cgttaataat tatttacatt ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctatgctgca tccactttgc aaagtggggt cccatctagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatgttgcga cttattactg
      361 tcagcatagt tatactaccc cgttcacttt cggtgggggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003511             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8665:15840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003511
VERSION     KCVT01003511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8665:15840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81036.1"
                     /translation="CQKYISSPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          129 c          106 g           92 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaacttat attgactcag
      121 tctccagcca ccctgtctct gtctccaggg gaaagagtca ccctctcctg cagggccagt
      181 cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc ccccaggctc
      241 ctcctctatg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt tgcagtatat
      361 tactgtcaga aatatattag ctccccattc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01003512             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16102:5546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003512
VERSION     KCVT01003512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16102:5546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81037.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003513             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20007:12651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003513
VERSION     KCVT01003513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20007:12651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81038.1"
                     /translation="CQRDYSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          119 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcatctta gcctggtacc accagaaacc tgggcaggct cccaagtccc
      241 tcatctatgg tgcaaccagt agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggcgtttatt
      361 actgtcagcg ggattatagc tggccactca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003514             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20865:9122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003514
VERSION     KCVT01003514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20865:9122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81039.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           91 t
ORIGIN      
        1 atggggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaaca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003515             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13685:5265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003515
VERSION     KCVT01003515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13685:5265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81040.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003516             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6887:7755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003516
VERSION     KCVT01003516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6887:7755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81041.1"
                     /translation="CQQSYRYPLTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          105 a          116 c          102 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaaac tcctcatgta
      241 tcttacatcc actttgcaaa atggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gctgcaactt attactgtca
      361 gcagagttat cgttatccgc tcactttcgg tggagggacc caggtggaaa tcaatcgag
//
LOCUS       KCVT01003517             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9280:4502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003517
VERSION     KCVT01003517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9280:4502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81042.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gtgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01003518             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11190:19700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003518
VERSION     KCVT01003518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11190:19700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81043.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          108 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gctagtcagg
      181 acattagtaa ttttttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg ggaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgcg acttatcatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01003519             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23134:20413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003519
VERSION     KCVT01003519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23134:20413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81044.1"
                     /translation="CQQDFGWPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          119 c          115 g           89 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagctcca gcacagcttc
       61 tcttcctcct gctactctgg atcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccattct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 ctgttggcag cgccttagcc tggtaccagc agaaacctgg gcagactcac aaactcctca
      241 tttatggtgc atccagcagg gccaccggca tcccagacag gttcagtggc agtgggtctg
      301 gaacagagtt cactctcacc atcagtagtc cggagcctga ggatgttgga gtttattact
      361 gtcagcagga ttttggctgg cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003520             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10951:15773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003520
VERSION     KCVT01003520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10951:15773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81045.1"
                     /translation="CQQAYSHPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          116 c          104 g          100 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccagatgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcacaaca
      181 tttatagtta tttagcgtgg tatcagcaga aaccagggaa agcccctaag ctcctgatat
      241 atgctacatc cagattgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cagagttcac tctcaccatc agcagcctgc agcctgaaga ttctgcaggt tattactgtc
      361 aacaggctta tagtcaccca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01003521             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9330:16941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003521
VERSION     KCVT01003521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9330:16941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81046.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt ctgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01003522             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21355:5454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003522
VERSION     KCVT01003522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21355:5454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81047.1"
                     /translation="CQQHDNSPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          117 c          109 g           87 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagag
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaggccccta acctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gataattccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003523             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:6435:11633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003523
VERSION     KCVT01003523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6435:11633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81048.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          124 g          100 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatggtctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcgtcg atagtgagga tggaaacacc tatttggaat ggcgcctgca gaagccaggc
      241 cagtctccac atctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gcgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003524             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17252:10280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003524
VERSION     KCVT01003524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17252:10280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81049.1"
                     /translation="CQKYISSPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          132 c          110 g           93 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaacttat
      121 attgactcag tctccagcca ccctgtctct gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcctctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcagtatat tactgtcaga aatatattag ctccccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01003525             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14742:18605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003525
VERSION     KCVT01003525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14742:18605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81050.1"
                     /translation="CLHYNSAPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          113 c          108 g          100 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatct tccctgtctg catctgtagg agacagagtc accatcactt gcagggcaag
      181 tcagggcatt agcaattatt taaattggtt tcagcagaaa ccaggaaaag ctcctaagcg
      241 cctgatctat gatgcatcca gtttgcaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gtattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cattataaca gtgcccctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003526             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21262:12724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003526
VERSION     KCVT01003526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21262:12724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81051.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           99 a          122 c          119 g          105 t
ORIGIN      
        1 acatgggggt ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagaacctcc tggatagtga ggatggaaac acctatttgc actggtacct gaagaagcca
      241 ggccagtctc cacagctctt aatttatgaa gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01003527             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13421:16871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003527
VERSION     KCVT01003527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13421:16871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81052.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcaaca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccattttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003528             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20483:11251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003528
VERSION     KCVT01003528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20483:11251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..438
                     /note="immunoglobulin light chain variable region"
     V_region        100..438
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81053.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagagt
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgagatt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcacagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cgtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003529             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12601:5368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003529
VERSION     KCVT01003529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12601:5368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81054.1"
                     /translation="CLQYKSFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          116 c          102 g          101 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtgggaga cactgtcacc atcacttgcc ggacaagtca
      181 aggtattacc aattatttac attggtttca acacaaacca ggggcagccc ctaagctcct
      241 gatctatgag acatccagtt tggtaagtgg cgtcccatca aggttcagcg gcagtgcatc
      301 tgggacagaa ttcactctca ccatcagcag cctacagcct gaagattttg catcttatta
      361 ctgtctgcag tataaaagtt tcccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003530             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14260:6569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003530
VERSION     KCVT01003530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14260:6569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..383
                     /note="immunoglobulin light chain variable region"
     V_region        44..383
     V_segment       44..346
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81055.1"
                     /translation="CIQSLEFPWTF"
     J_segment       347..383
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           85 a           99 c          107 g           95 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccac cgggacattg tgatgaccca
       61 gactccactc tccctgcccg tcacccttgg agagccggcc tccttctcct gtaggtctag
      121 tcacagcctc ttggatagtg aggatggaaa tatccatttg gattggtatc tgcagaagcc
      181 aggccagtct ccacacctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      241 caggtttagt ggcagtgggt cagacactga tttcacactg aaaatcagca gggtggaggc
      301 tgaggatgtt ggggtttact actgcataca atctctagag tttccttgga cgttcggcca
      361 ggggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01003531             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21984:23833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003531
VERSION     KCVT01003531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21984:23833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81056.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcaca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003532             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16818:12191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003532
VERSION     KCVT01003532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16818:12191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81057.1"
                     /translation="CLQYRSYPYNF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          110 c          105 g           96 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatcac ttgccgggca agtcaggata
      181 ttagcagtta tttaaattgg tttcagaaga aaccagggaa agcccctaag ctcctgatcc
      241 aagctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtatag aagttacccg tacaattttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003533             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12647:10517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003533
VERSION     KCVT01003533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12647:10517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..373
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81058.1"
                     /translation="CQQGYYTPFTF"
     J_segment       388..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT           98 a          122 c          112 g           96 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgcccga tgtgacatcc agatgaccca
      121 gtctccatcg tccctgtctg catctgtagg agacaaagtc accatctctt gccgagccag
      181 tcagggtatt agcagctggt tagcctggta tcagcagaaa ccagggaaag cccctaagct
      241 cctgatctat aaggcgtcca gtttggcaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggacg gattacactc tcaccatcag cagcctgcag cctgaagatt ttgctactta
      361 ttattgtcaa cagggttact ataccccatt cactttcggc cccgggacca aactggatat
      421 caatcgag
//
LOCUS       KCVT01003534             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21634:4479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003534
VERSION     KCVT01003534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21634:4479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81059.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt tcctgcaggt cgagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cggtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003535             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17423:12126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003535
VERSION     KCVT01003535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17423:12126"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81060.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tgtcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003536             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10389:7174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003536
VERSION     KCVT01003536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10389:7174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81061.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          108 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 gtattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003537             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:25656:7687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003537
VERSION     KCVT01003537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:25656:7687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81062.1"
                     /translation="CQQYNSYPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          105 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcagttat ttagcctggt atcagcagaa accagggaaa gcccctaagc gcctgatcta
      241 tgctgcatcc actttgcaaa gtggggtccc atcaagattc agcggcagtg gatctgtgac
      301 agatttcact ctcaccatca gcagcctaca gcctgaagat tttgcaactt attactgtca
      361 acagtataat agttatccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003538             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13050:19780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003538
VERSION     KCVT01003538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13050:19780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81063.1"
                     /translation="CQQYNSLPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          108 c          110 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcttc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cagtttttta aattggtatc agcagaaacc ggggaaagcc cctaaggccc
      241 tgatctatta tgcaaaccgg ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaatc tgaagatttt gcaacttatt
      361 actgtcaaca gtataatagt ttaccgtaca gttttggcca ggggaccaaa gtagagatca
      421 aacgag
//
LOCUS       KCVT01003539             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:21677:20349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003539
VERSION     KCVT01003539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21677:20349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81064.1"
                     /translation="CHQHNSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagaaacagt caccgtcact tgtcgggcaa gtcggggcgt
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaggc ccctgatcta
      241 ctatgcatcc aatttggaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcacaatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 ccaacataat agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003540             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16427:4429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003540
VERSION     KCVT01003540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16427:4429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81065.1"
                     /translation="CLQGYITPYSF"
     J_segment       269..306
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           79 a           73 c           80 g           77 t
ORIGIN      
        1 acatgggatc ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa
       61 gtcaggacat tagcgatttt ttaagttggt atcagcagaa accaggaaaa cttcctaagc
      121 gcctgattta tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg
      181 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt
      241 attactgtct acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga
      301 tcaaacgag
//
LOCUS       KCVT01003541             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23300:7002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003541
VERSION     KCVT01003541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23300:7002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..265
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81066.1"
                     /translation="CQQYDSDSLTF"
     J_segment       270..307
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>310
                     /gene="IGKC"
BASE COUNT           80 a           78 c           81 g           71 t
ORIGIN      
        1 acatgggcat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg
       61 agtcagggca ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag
      121 cccttgatct attacgcgtc cactttggaa agtggggtcc catcaagatt cagcggcagt
      181 ggatctggga cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact
      241 tattactgtc aacagtatga cagtgactcg ctcactttcg gtggagggac caaggtagag
      301 atcaaacgag
//
LOCUS       KCVT01003542             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7711:7615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003542
VERSION     KCVT01003542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7711:7615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..347
                     /note="immunoglobulin light chain variable region"
     V_region        11..347
     V_segment       11..309
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <287..>319
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81067.1"
                     /translation="CGQGTHLPWTF"
     J_segment       310..347
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>350
                     /gene="IGKC"
BASE COUNT           88 a           91 c           97 g           74 t
ORIGIN      
        1 acatgggggg gatgttgtga tgactcagtc tccactctcc ctgtccatca cccctggaca
       61 gccggcctcc atctcctgca ggtctagtca aagccttgta cacatcaatg gaaacacata
      121 cttgagttgg tatcagcaga acccaggcca acctccaagg cgcctaattt atgaggtttc
      181 taaccgggac tctggggtcc cagacagatt cagcggcagt ggggcaggga cagatttcac
      241 actgaaaatc agcagagtgg aggctgagga tgttgggctt tattactgcg ggcaaggtac
      301 acaccttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01003543             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12865:11646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003543
VERSION     KCVT01003543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12865:11646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81068.1"
                     /translation="CMQALEFLLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          118 c          127 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttct tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003544             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22096:13555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003544
VERSION     KCVT01003544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22096:13555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81069.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccagtt tggaaagtgg ggtcccatca aggttcagcg gcggtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagacatcaa
      421 acgag
//
LOCUS       KCVT01003545             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16186:7889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003545
VERSION     KCVT01003545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16186:7889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81070.1"
                     /translation="CQQGYSYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          119 c          104 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgatgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcacggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tacggcatcc aggttacaag gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcggcctgca gcctgaagat cttgccactt attactgtca
      361 acagggttat agttacccat tcactttcgg tcccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003546             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13057:14337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003546
VERSION     KCVT01003546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13057:14337"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..445
                     /note="immunoglobulin light chain variable region"
     V_region        124..445
     V_segment       124..407
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81071.1"
                     /translation="CQQGSPFPWTF"
     J_segment       408..445
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT          112 a          116 c          116 g          104 t
ORIGIN      
        1 acatggggga ggctctttct ctgggatgtg gcatgagcaa aactgacaag tcaaggcagg
       61 aagatgttgt ctccatcaca actcattggg tttctgctgc tctgggttcc agcctccaag
      121 ggtgaaattg tgctgactca gtctccagcc tttcggtctg tgactctaaa ggagaaagtc
      181 accatcacct gccaggccag tcagagcatt ggtaatagct tacactggta ccagcagaaa
      241 ccggatcagt ctccaaagct cctcatcaaa tatgcttccc agtccatctc aggggtcccc
      301 tcaaggttca gtggcagtgg atctgggaca gatttcaccc tcaccatcaa tagcctggaa
      361 gctgaagatg ctgcgacgta ttactgtcag cagggaagtc ctttcccgtg gacgttcggc
      421 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003547             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20835:8687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003547
VERSION     KCVT01003547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20835:8687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81072.1"
                     /translation="CQQYHSLPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          111 c          107 g           98 t
ORIGIN      
        1 acatggggca gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagtaatta tttaaattgg tatcaacaga aaccggggag agcccctaag gtcctgatgt
      241 actatacaaa ccgtttggaa ggtggggtcc cctcaaggtt cagcggcagt ggatctggga
      301 cagaatttac tctcaccatc agcagcctgc aacctgaaga ttttgcatct tattactgtc
      361 aacagtatca tagtttacct ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003548             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14410:6842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003548
VERSION     KCVT01003548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14410:6842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..303
                     /note="immunoglobulin light chain variable region"
     V_region        19..303
     V_segment       19..266
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <243..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81073.1"
                     /translation="CMQALEFPLTF"
     J_segment       269..303
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>306
                     /gene="IGKC"
BASE COUNT           75 a           70 c           87 g           74 t
ORIGIN      
        1 acatggggga tcacgactcc tccatctcct gtaggtctag tcagagcctc ttggatagtg
       61 aagatggaaa tacctatttg gaatggcacc ggcagatgcc aggccagtct ccacagctct
      121 tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt ggcagtgggt
      181 cagacactga tttcactctg aaaatcagca gagtggaggc tgaggatgtt ggggtttatt
      241 actgcatgca agctctagag tttcctctga cgttcggcca agggaccaag gtggaaatca
      301 aacgag
//
LOCUS       KCVT01003549             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13811:13981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003549
VERSION     KCVT01003549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13811:13981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81074.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtgggag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003550             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16128:10506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003550
VERSION     KCVT01003550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16128:10506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81075.1"
                     /translation="CMQGIQLPPTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           86 a          126 c          124 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctgc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctccaact tggtaatgga tacacttatc tgttttggta cctgcagaag ccgggccagt
      241 ctccacagct cctgatctat ttgctttccg gccgggcctc tggagtccct gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caaggtatac agcttcctcc gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01003551             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11245:16033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003551
VERSION     KCVT01003551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11245:16033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81076.1"
                     /translation="CMQALEFPLTF"
     J_segment       348..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           97 c          108 g           95 t
ORIGIN      
        1 acatggtggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcatgtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc
      181 caggccagtc tccacagctc ttgatttatg aggtttccat acgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagt agagtggagg
      301 ctgaggatgt tgggatttat tactgcatgc aagctctaga gtttcctctc actttcggcg
      361 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01003552             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:6985:12465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003552
VERSION     KCVT01003552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6985:12465"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81077.1"
                     /translation="CMQSLEFPLTF"
     J_segment       275..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           70 a           80 c           88 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cacagctctt gatttatgag gtctccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactaat ttcacactga gaatcagtag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa tctctagagt ttccgctcac tttcggtgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01003553             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15433:16019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003553
VERSION     KCVT01003553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15433:16019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81078.1"
                     /translation="CQQYNSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          113 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003554             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18933:15630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003554
VERSION     KCVT01003554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18933:15630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81079.1"
                     /translation="CQQHNTYPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          118 c          106 g           93 t
ORIGIN      
        1 acatggggag agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagt aatgatttag cctggtatca gcagaaacca gggaaagccc cgaaacccct
      241 gatcttttac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataatactt acccgtacac ttttggccag gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003555             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23856:13080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003555
VERSION     KCVT01003555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23856:13080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81080.1"
                     /translation="CQQYNSLYSF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          109 c          110 g           98 t
ORIGIN      
        1 acatggggca ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg ccgggcaagt
      181 caggccatta gtagttattt aaattggtat cagcagaaac cgggggaagc ccctaagctc
      241 ctgatctatt atgtgaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctccaac ctgaggattt tgcaacttat
      361 tactgtcaac agtataatag tttatacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003556             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16905:5486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003556
VERSION     KCVT01003556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16905:5486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81081.1"
                     /translation="CQQDFGWPPTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          103 a          122 c          122 g           91 t
ORIGIN      
        1 acatggggca gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ctccagcaca gcttctcttc ctcctgctac tctggatccc agataccacc ggagaaatag
      121 tgatgacgca gtctccagcc attctgtctt tgtctccagg ggaaagagcc accctctcct
      181 gcagggccag tcagactgtt ggcagcgcct tagcctggta ccagcagaaa cctgggcaga
      241 ctcacaaact cctcatttat ggtgcatcca gcagggccac cggcatccca gacaggttca
      301 gtggcagtgg gtctggaaca gagttcactc tcaccatcag tagtccggag cctgaggatg
      361 ttggagttta ttactgtcag caggattttg gctggcctcc gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01003557             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19372:12493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003557
VERSION     KCVT01003557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19372:12493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..383
                     /note="immunoglobulin light chain variable region"
     V_region        104..383
     V_segment       104..345
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81082.1"
                     /translation="CLQFKTYPNSF"
     J_segment       348..383
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           95 a          111 c           93 g           87 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatctctt gccgggcaag
      181 tcagggtatt agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctcagca
      241 ccctgacgct gagcagcaca gactaccaga attctctctc accatcacca gcctgcagcc
      301 tgaagatttt gcaacttatt tctgtctgca gtttaaaact tacccgaaca gttttggcca
      361 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01003558             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16946:3964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003558
VERSION     KCVT01003558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16946:3964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81083.1"
                     /translation="CQQYNSLPFSF"
     J_segment       382..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          109 c          105 g          100 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccaa ttgtgacatt cagatgaccc agtctccatc
      121 ctccgtgtct gcctctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcttctat ttaaattggt atcagcataa accggggaaa gcccctgagc tcctgatgta
      241 ttattcaaac cgtttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acaatataat agtttgccgt tcagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003559             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17415:5415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003559
VERSION     KCVT01003559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17415:5415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81084.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ttggttggcc tggtatcaac agaaaccagg aaaagcccct aacctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatttg
      301 gtacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003560             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16696:9860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003560
VERSION     KCVT01003560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16696:9860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..465
                     /note="immunoglobulin light chain variable region"
     V_region        126..465
     V_segment       126..428
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <405..>437
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81085.1"
                     /translation="CMQALEFPLTF"
     J_segment       429..465
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        466..>468
                     /gene="IGKC"
BASE COUNT          104 a          124 c          130 g          110 t
ORIGIN      
        1 acatgggaag cagtggttca accagagtac atggggatca cgactcctca ggtcaccttc
       61 tcacaatgag gctccctgct cagctcctgg gactgctaat gctctggctc cctgggtcca
      121 gtggggacat tgtgatgacc cagactccac tctccctgcc cgtcaccctt ggagagccgg
      181 cctccatctc ctgcaggtct agtcagagcc tcttggatgg tgaggatgga aacacctatt
      241 tggaatggta cctgcagaag ccaggccagt ctccacagct cttgatttat gaggtttcca
      301 accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact gatttcacac
      361 tgaaaatcag cagagtggag gctgaggatg ttgggattta ttactgcatg caagctctag
      421 agtttcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003561             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6919:2876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003561
VERSION     KCVT01003561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6919:2876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81086.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgct acttatttct
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003562             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10297:6262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003562
VERSION     KCVT01003562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10297:6262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81087.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          128 c          113 g           84 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggac aaatagtgct gacgcagtct
      121 ccagccaccc tgtccttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcctagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctttggtg catccaacag ggccactggc atcccaggca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga acagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003563             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:19924:14531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003563
VERSION     KCVT01003563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19924:14531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81088.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagccaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003564             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12986:9670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003564
VERSION     KCVT01003564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12986:9670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..394
                     /note="immunoglobulin light chain variable region"
     V_region        58..394
     V_segment       58..356
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81089.1"
                     /translation="CMQSIKDPFTF"
     J_segment       357..394
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           92 a          108 c          102 g           95 t
ORIGIN      
        1 acatgggctg ctcagctcct cgggctgttg atgctctggg tccctggatc cagtggggat
       61 attgtgatga cccagacccc actctcggtg cccgtcaccc ctggagagcc ggcctccatc
      121 tcctgcaggt ctagtcaaag ccttctccat agtaatggag acacctattt acattggtac
      181 cttcagaggt caggccagtc tccacggctc ctgatctata aagtaaccaa tcggctacct
      241 ggggtcccag acaggttcag tggcagtggg tcaggcacag atttcacact gaaaatcagc
      301 agggtggagc ctgaggatat tggtgtttat ttctgcatgc aaagtataaa agatccattc
      361 actttcggcc ccgggaccaa actggatatc aaacgag
//
LOCUS       KCVT01003565             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17191:20884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003565
VERSION     KCVT01003565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17191:20884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81090.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          120 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003566             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:2838:12026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003566
VERSION     KCVT01003566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:2838:12026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81091.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctacagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003567             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8702:18849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003567
VERSION     KCVT01003567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8702:18849"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81092.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          126 c          113 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccaccaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003568             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16340:3645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003568
VERSION     KCVT01003568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16340:3645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81093.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          114 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg agcctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003569             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13429:12383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003569
VERSION     KCVT01003569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13429:12383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..414
                     /note="immunoglobulin light chain variable region"
     V_region        101..414
     V_segment       101..384
                     /gene="IGKV3-52"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81094.1"
                     /translation="CQNYNDWPLTF"
     J_segment       385..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>425
                     /gene="IGKC"
BASE COUNT           93 a          125 c          116 g           91 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tgccaccgga gaaactgtga tgatgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccaggca
      181 gagtgttggc agcaccttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctattct gcatccacca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggtcagat ttcactctca ccatcagcag tctggatcct gaagatgttg gagtttatta
      361 ctgtcagaac tacaatgact ggccgctcac tttcggtgga gggaccaagg tggatctcag
      421 acgag
//
LOCUS       KCVT01003570             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18691:13173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003570
VERSION     KCVT01003570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18691:13173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81095.1"
                     /translation="CQQYSTLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          110 c          112 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 caccctccct gtccgcatct gaaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 gcattggtta ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaatcgtttg gaaagtgggg tcccatcaag ggtcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta tagtacttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003571             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:5313:13413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003571
VERSION     KCVT01003571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5313:13413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81096.1"
                     /translation="CQQGYSYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccctc
      121 ctccctgtcc gcatctgtag gagacgcagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt ttcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctggggc
      301 ggatttcact ctcaccatca ccagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttacccgt ggacgttcgg ccaaggggcc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003572             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13916:18839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003572
VERSION     KCVT01003572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13916:18839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81097.1"
                     /translation="CLQYKTYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          111 c          106 g          100 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcttct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 gtattgctgg ttatttaaat tggtttcaga agaaaccagg gaaagcccct aagctcctga
      241 tccaagctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaacttat ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003573             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10962:2965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003573
VERSION     KCVT01003573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10962:2965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81098.1"
                     /translation="CIQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          124 c          118 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cctctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggc tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaatacc tatttggaat ggtacctcca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga cttattactg catccaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003574             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14311:20026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003574
VERSION     KCVT01003574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14311:20026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81099.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaccgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct ctagagtttc cttggacgtt cggccagggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003575             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20402:10825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003575
VERSION     KCVT01003575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20402:10825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..365
                     /note="immunoglobulin light chain variable region"
     V_region        88..365
     V_segment       88..323
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81100.1"
                     /translation="CQQYESDSLTF"
     J_segment       328..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           93 a           94 c          101 g           80 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagtc accatcactt gtcgggcgac
      121 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaaggc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag tagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa cagtatgaaa gtgattcgct cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01003576             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22600:9649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003576
VERSION     KCVT01003576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22600:9649"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81101.1"
                     /translation="CQQDFGWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g           90 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ttctgtcttt gtctccaggg gaaagagcca ctctctcctg cagggccagt
      181 cagactgttg gcagcgcctt agcctggtac cagcagagac ctgggcagac tcacaaactc
      241 ctcgtttatg gtgcatccag cagggccacc ggcatcccag acaggttcag tggcagtggg
      301 tctggaacag agttcactct caccatcagt agtccggagc ctgaggatgt tggagtttat
      361 tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01003577             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15489:5931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003577
VERSION     KCVT01003577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15489:5931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81102.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01003578             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13536:14003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003578
VERSION     KCVT01003578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13536:14003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81103.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gatgctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003579             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13396:8570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003579
VERSION     KCVT01003579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13396:8570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81104.1"
                     /translation="CQQDFDWPPTF"
     J_segment       384..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           97 a          125 c          111 g           88 t
ORIGIN      
        1 atgggggaac tgctcagtta ggacccagag ggaaccatgg aagctccagc acagcttctc
       61 ttcctcctgc tactctggat cccagatacc accggagaag ttgtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccaccctct cctgcagggc cagtcagagt
      181 gttggcaaca ccttaacctg gtaccagcac aaacctgggc aggctcccaa gctcctcctc
      241 tatggtgcat ccaccagggc ctccggcatc ccaggcaggt tcagtgccag tgggtctgga
      301 acagagttta ctctcaccat cagcagcctg gagcctgaag atgttggaat ttattactgt
      361 cagcaggatt ttgactggcc tccgacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01003580             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14324:8228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003580
VERSION     KCVT01003580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14324:8228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81105.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003581             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14701:4093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003581
VERSION     KCVT01003581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14701:4093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81106.1"
                     /translation="CQQVYSNPAF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          111 c          108 g           99 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccaggtg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag gaatttagcg tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc atccagattg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcaacc tacagcctga agattctgca atttattact
      361 gtcaacaggt ttatagtaac ccggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01003582             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20093:13766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003582
VERSION     KCVT01003582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20093:13766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81107.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggta tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003583             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24778:13902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003583
VERSION     KCVT01003583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24778:13902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81108.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          119 c          106 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003584             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24340:8635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003584
VERSION     KCVT01003584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24340:8635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81109.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          107 c          111 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agatatttaa attggtatca gcagaaaccg gggaaagccc ctaagttcct
      241 gatctattat gtaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcaacct gaagattttg caacttatta
      361 ttgtcaacag tataatagtt taccgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003585             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:26229:8266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003585
VERSION     KCVT01003585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:26229:8266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81110.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          110 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga gagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctttggt acatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tcgaacagag tttactttca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003586             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22196:2264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003586
VERSION     KCVT01003586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22196:2264"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81111.1"
                     /translation="CQQGYSYPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          121 c          105 g           94 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcccccct gtccgcatct ataggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattgacaa taatttaaat tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctttggggc atccactttc caaagtggga ctccctcgcg gttcagcggc agtgaatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttatttct
      361 gtcaacaggg ttatagttac cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003587             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20864:13596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003587
VERSION     KCVT01003587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20864:13596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81112.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          123 c          109 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacgtct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01003588             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11645:3567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003588
VERSION     KCVT01003588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11645:3567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81113.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactccccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagtcaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003589             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22188:9613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003589
VERSION     KCVT01003589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22188:9613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81114.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggcag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003590             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16439:3801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003590
VERSION     KCVT01003590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16439:3801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81115.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003591             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21139:19118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003591
VERSION     KCVT01003591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21139:19118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81116.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc cgctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003592             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12811:24184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003592
VERSION     KCVT01003592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12811:24184"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81117.1"
                     /translation="CQQDFGWPPTF"
     J_segment       392..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          101 a          119 c          119 g           90 t
ORIGIN      
        1 acatgggggg ggaggaactg ctcagttagg acccagaggg aaccatggaa gctccagcac
       61 agcttctctt cctcctgcta ctctggatcc cagataccac cggagaaata gtgatgacgc
      121 agtctccagc cattctgtct ttgtctccag gggaaagagc caccctctcc tgcagggcca
      181 gtcagactgt tggcagcgcc ttagcctggt accagcagaa acctggccag actcacaaac
      241 tcctcattta tggtgcatcc agcagggcca ccggcatccc agacaggttc agtggcagtg
      301 ggtctggaac agagttcatt ctcaccatca gtagtccgga gcctgaggat gttggagttt
      361 attactgtca gcaggatttt ggctggcctc cgacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01003593             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17997:13407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003593
VERSION     KCVT01003593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17997:13407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81118.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctccttga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaac cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003594             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13807:10139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003594
VERSION     KCVT01003594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13807:10139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81119.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactgtccc tgcccgtcac ccttggagag ccggcctcca tctcctgtgg gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003595             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:4527:14869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003595
VERSION     KCVT01003595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4527:14869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81120.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcggcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01003596             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5383:17137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003596
VERSION     KCVT01003596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5383:17137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81121.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          123 c          111 g           85 t
ORIGIN      
        1 acatggggaa ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcagc agcgtagcct ggtaccagca aaaacctggg caggctccca gactcctcat
      241 ctatggtgca tccaacaggg ccactggcat cccagacaga ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gatgttgcac tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003597             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:4531:20436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003597
VERSION     KCVT01003597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4531:20436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81122.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcagt tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003598             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15549:16270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003598
VERSION     KCVT01003598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15549:16270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81123.1"
                     /translation="CQHSFRTPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           99 a          115 c          108 g           96 t
ORIGIN      
        1 acatgggggt ctcagtcagg acacagcatg gacatgaggg cctctgctca gctcctaggg
       61 ctcctgctgc tctggctccc aggcgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc aatgtcactt gcagggctag tgagagcgtt
      181 agcaccaaat tacattggta tcagcagaaa ccagggaaag cccctaagct cctgatcttt
      241 gctgcgtcca ctttgcaaag tggggtccca tcaaggttca gcggcagtgg atctggaaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatg tcgcaacttt ttactgtcag
      361 catagttttc gtaccccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01003599             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23311:3840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003599
VERSION     KCVT01003599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23311:3840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81124.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          128 c          120 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cacggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01003600             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5347:9777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003600
VERSION     KCVT01003600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5347:9777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81125.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          124 c          123 g          102 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgact tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01003601             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7534:9981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003601
VERSION     KCVT01003601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7534:9981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..381
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81126.1"
                     /translation="CQQVLTNPAF"
     J_segment       384..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          113 c          106 g           99 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccctg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgat atccaggtga cccagtctcc
      121 atctgccttg tctgcatctg taggagacag agtcaccatc tcttgccggg caagtcagaa
      181 catttatagg aatttagcgt ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 ctatgctgca tccagattgc aaagtgggtt tccctctcgg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcaacct acagcctgaa gattctgcaa tttattactg
      361 tcaacaggtt cttactaacc cggcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003602             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24929:17893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003602
VERSION     KCVT01003602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24929:17893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81127.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          120 c          105 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gtacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003603             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15243:12190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003603
VERSION     KCVT01003603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15243:12190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81128.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003604             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:23876:11703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003604
VERSION     KCVT01003604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23876:11703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81129.1"
                     /translation="CQQGDSYPRTF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          111 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag attgacattc agatgtccca gtctccttcc
      121 tccctgtctg catctgtggg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 agagattatt taaattggta tcagcagcaa ccggggaaag cccctaaact cctgatgtat
      241 tatgcaaaca gtctggcaag tggagtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcagtc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagggtgaca gttatcctcg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003605             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19283:19613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003605
VERSION     KCVT01003605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19283:19613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..386
                     /gene="IGKV3-52"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81130.1"
                     /translation="CQNYNDWPLTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>427
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g           92 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaactgt gatgatgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagg
      181 cagagtattg gcagcacctt agcctggtac cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatctatt ctgcatccac cagggccact ggcatcccag acaggttcag tggtagtggg
      301 tctgggtcag atttcactct caccatcagc agtctggatc ctgaagatgt tggagtttat
      361 tactgtcaga attacaatga ctggccgctc actttcggtg gagggaccaa ggtggagatc
      421 agacgag
//
LOCUS       KCVT01003606             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13902:17720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003606
VERSION     KCVT01003606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13902:17720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81131.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          108 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003607             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13597:11015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003607
VERSION     KCVT01003607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13597:11015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81132.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01003608             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15249:2807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003608
VERSION     KCVT01003608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15249:2807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81133.1"
                     /translation="CEQGYIFPFTF"
     J_segment       381..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          117 c          104 g          101 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcaatag tttaagttgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 atagggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt agatctggga
      301 cggatttcac tctcaccatc agcagcctgc agtctgaaga ttttgccact tattattgtg
      361 aacagggtta tattttcccc ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01003609             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13195:14172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003609
VERSION     KCVT01003609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13195:14172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81134.1"
                     /translation="CQQHDNSPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          119 c          112 g           89 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tctctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggtgttagcg actggttggc ctggtatcaa cagagaccag ggaaagcccc taaactcctg
      241 atctataggg cgtccaattt ggatacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc tacatattac
      361 tgtcaacagc atgataattc ccctccgacg ttcggccaag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003610             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20902:4231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003610
VERSION     KCVT01003610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20902:4231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81135.1"
                     /translation="CQQYNSGPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          118 c          103 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc agccaaagcc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt gccagtggat
      301 ctgggacaga attcactctc accatcagca gtctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt ggcccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01003611             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17906:18120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003611
VERSION     KCVT01003611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17906:18120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81136.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          100 a          110 c          109 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagag accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggccg agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01003612             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11679:9401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003612
VERSION     KCVT01003612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11679:9401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81137.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          120 c          107 g           91 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003613             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22671:20502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003613
VERSION     KCVT01003613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22671:20502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81138.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg ggaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003614             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:2893:16326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003614
VERSION     KCVT01003614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:2893:16326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81139.1"
                     /translation="CQQYNSDPRTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          119 c          113 g           91 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaac ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtataaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003615             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15174:10150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003615
VERSION     KCVT01003615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15174:10150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81140.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggtt ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003616             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16447:5713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003616
VERSION     KCVT01003616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16447:5713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81141.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cactcttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt aatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01003617             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7202:7642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003617
VERSION     KCVT01003617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7202:7642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81142.1"
                     /translation="CQQGYNTPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          116 c          115 g           89 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcagggtat
      181 tagcagctgg ttagcctggt atcagcagaa accagggcaa gcccctaatc tcctgatcta
      241 taaggcgtcc agtttggcaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagggttac aataccccgt ggacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003618             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16413:14233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003618
VERSION     KCVT01003618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16413:14233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81143.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003619             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20975:5546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003619
VERSION     KCVT01003619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20975:5546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81144.1"
                     /translation="CQQHNSYPTTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          119 c          106 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagtc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tgtattacgc atccaatttg caaagtgggg tcccatcaag gtttagcggc agtggatctg
      301 ggacagactt cactctcacc atcagcagtc tgcagcctga agactttgca acttattact
      361 gtcaacagca taatagttac cctaccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003620             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18183:11479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003620
VERSION     KCVT01003620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18183:11479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81145.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          119 c          104 g           92 t
ORIGIN      
        1 acatgggagt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattatgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaacat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003621             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14381:16056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003621
VERSION     KCVT01003621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14381:16056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81146.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgctgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgtaggtcta gtcagagcct
      181 cttggatagt gaggatggaa atacctattt ggaatggcac cggcagatgc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttcctctg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01003622             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4997:12871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003622
VERSION     KCVT01003622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4997:12871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81147.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003623             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21006:16719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003623
VERSION     KCVT01003623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21006:16719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81148.1"
                     /translation="CLQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           87 a          124 c          121 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctcca taggaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgctta caagatatac agcttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01003624             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21744:7200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003624
VERSION     KCVT01003624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21744:7200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81149.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          113 c          111 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003625             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21517:7892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003625
VERSION     KCVT01003625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21517:7892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..415
                     /note="immunoglobulin light chain variable region"
     V_region        101..415
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81150.1"
                     /translation="CQQYNTLPLTF"
     J_segment       385..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacactcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaac atttatttaa attggtatca gcagaaaccg gggaaagccc ctgagctcct
      241 gatctattat gcaaaccgtt tggaaactgg ggtcccatca aggttcagcg gcggtggatc
      301 tgggacagaa ttcagtctca ccatcagcag cctgcaacct gaggactttg caacttatta
      361 ctgtcaacag tataatactt taccgctcac tttcggcgga gggaccaagg tggaggtcag
      421 acgag
//
LOCUS       KCVT01003626             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18142:18874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003626
VERSION     KCVT01003626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18142:18874"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..349
                     /note="immunoglobulin light chain variable region"
     V_region        28..349
     V_segment       28..312
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81151.1"
                     /translation="CQQHADSPRTF"
     J_segment       314..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           94 a           96 c           89 g           73 t
ORIGIN      
        1 acatgggggc tcccaggtgc cagatgtgac atccagatga cccagtctcc atcctccctg
       61 tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcaggg tattagcaac
      121 tggttggcct ggtatcaaca gagaccaggg aaagccccta aggtcctgat ctataggaca
      181 tccaatttgg aaacaggggt cccatcaagg ttcagtggaa ccggatctgg gacagatttc
      241 actctcacca tcagcagcct gcagcctgaa gatttcgcaa catattactg tcaacagcat
      301 gctgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003627             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22401:18233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003627
VERSION     KCVT01003627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22401:18233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..240
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81152.1"
                     /translation="CMQALEFPPFTF"
     J_segment       243..280
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>283
                     /gene="IGKC"
BASE COUNT           70 a           64 c           79 g           70 t
ORIGIN      
        1 acatgggggt ctagtcagag cctcttggat agtgaggatg gaaacaccta tttggaatgg
       61 tacctgcaga agccaggcca gtctccacag ctcttgattt atgaggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      181 agcagagtgg aggctgagga tgttggggtt tattattgca tgcaagctct agagtttcct
      241 ccattcactt tcggccccgg gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01003628             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23339:12143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003628
VERSION     KCVT01003628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23339:12143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81153.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          109 c          109 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 agacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003629             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10464:11496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003629
VERSION     KCVT01003629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10464:11496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..321
                     /note="immunoglobulin light chain variable region"
     V_region        122..321
     V_segment       122..283
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <261..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81154.1"
                     /translation="CMQALEFPFTF"
     J_segment       284..321
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>324
                     /gene="IGKC"
BASE COUNT           71 a           89 c           84 g           80 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      181 ggttcagtgg cagtgggtca gacactgatt tcacactgat aatcagcaga gtggaggctg
      241 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcacc ttcggccccg
      301 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01003630             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11362:15189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003630
VERSION     KCVT01003630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11362:15189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81155.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003631             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10432:12637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003631
VERSION     KCVT01003631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10432:12637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81156.1"
                     /translation="CQQYQSFPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          114 c          107 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtcg gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtagttat ttaaattggt ttcagcagca accggggaaa gcccctaagc tcctgctcta
      241 ttatacaaac cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgctactt attactgtca
      361 acagtatcag agttttcctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003632             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23128:2437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003632
VERSION     KCVT01003632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23128:2437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81157.1"
                     /translation="CQQYDSFPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          116 c          101 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttatttaaa ctggtatcag cagaaaccgg ggaaagcccc taaactcctg
      241 atctattata caaatcgttt ggaaactggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt atgatagttt tccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003633             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19131:8788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003633
VERSION     KCVT01003633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19131:8788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81158.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggccgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003634             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14574:6182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003634
VERSION     KCVT01003634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14574:6182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81159.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgggg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01003635             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:26917:10748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003635
VERSION     KCVT01003635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:26917:10748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81160.1"
                     /translation="CEQYNSLPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          112 a          112 c          103 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaaca tttatttaaa ttggtatcac cagaaaccgg ggaaagcccc taagctcctg
      241 atctattata caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtgaacaat acaatagttt accgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003636             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9419:7110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003636
VERSION     KCVT01003636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9419:7110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81161.1"
                     /translation="CLQDYNTPYNF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          112 c          109 g           94 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagttgacc cagtctccat
      121 cttccctgtc tgcatcggta ggagacagag tcaccatcac ctgccgggca agtcaggaca
      181 ttagcgatta tttaagttgg tatcagcaga aaccaggaaa agctcctaag cgcctgatct
      241 atgctgtgtc cagtttggaa ggtggggtcc catcaagatt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga tcttgcgact tattactgtc
      361 tacaggatta taataccccg tacaattttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003637             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19864:6504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003637
VERSION     KCVT01003637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19864:6504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81162.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          124 c          114 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc aacagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01003638             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8300:7184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003638
VERSION     KCVT01003638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8300:7184"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81163.1"
                     /translation="CMQALEFPLTF"
     J_segment       348..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           86 a           97 c          111 g           93 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcactcttg gagagccggc ctccatctcc tgcaggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc
      181 caggccagtc tccacgactc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttcctctc actttcggtg
      361 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01003639             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:7002:17899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003639
VERSION     KCVT01003639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7002:17899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..422
                     /note="immunoglobulin light chain variable region"
     V_region        95..422
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81164.1"
                     /translation="CQQRNGYPYIYSF"
     J_segment       386..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g          100 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtaccat atgtgacact cagttgaccc agtctccatc
      121 ctccctgtct gcgtctgtag gagacagagt caccatcact tgtcggacaa gtcaggacat
      181 tagcagttct ttagcctggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 taaggcgtcc agtttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca ggctgaagat tttgcagttt attactgtca
      361 acagcgtaat ggttacccgt atatctacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003640             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:17076:7586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003640
VERSION     KCVT01003640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17076:7586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81165.1"
                     /translation="CMQGLEFPITF"
     J_segment       402..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          124 c          115 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat actgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgatgtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagacg ctgatttcac actgagaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcca atcactttcg gccccgggac
      421 caaactggag atcaaacgag
//
LOCUS       KCVT01003641             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15874:7553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003641
VERSION     KCVT01003641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15874:7553"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81166.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          117 c          126 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca ccctgggaga gccggcctcc atgtcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggcacctgc agaggccagg
      241 ccagtctcca cagctcttga tttatgaggt ttcctatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003642             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4834:16692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003642
VERSION     KCVT01003642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4834:16692"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81167.1"
                     /translation="CQQDYHWPPTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          105 a          127 c          118 g           88 t
ORIGIN      
        1 acatggggca gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ctccagcaca gcttctcttc ctcctgctac tctggatccc agataccacc ggagacatag
      121 tgatgacgca gtctccagcc accctgtctt tgtctccagg ggaaagagcc accctctcct
      181 gcagggccag tcagagtgtt ggcagcacct taacctggta ccaccagaag cctgggcagg
      241 ctcccaagct cctcatctat ggtccatcca tcagggccag cggcatccca gacaggttca
      301 gtggcagtgg gtctggaaca gaatttactc tcaccatcag cagcctggag actgaagatg
      361 ttggagttta ttactgtcag caggattatc actggcctcc gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01003643             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18684:9729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003643
VERSION     KCVT01003643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18684:9729"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81168.1"
                     /translation="CQQGYGFPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          118 c          103 g          101 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcgcgatcac ttgcctggcg agtcaaggca
      181 ttggcaataa tttaaattgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 atacggcatc caatttacat ggtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc aacagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tggttttcca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01003644             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16250:12231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003644
VERSION     KCVT01003644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16250:12231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..392
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81169.1"
                     /translation="CLQSKNSPWSF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          116 c          118 g           99 t
ORIGIN      
        1 acatgggggg agcagcctct agttcagctc tcagaaatgg ggtcctgggc tcctttcctg
       61 tggatcctcc tgctctgtgc tccaggctgc agtggggaca ttgtgctgac ccagtctcca
      121 gcctctttgg ccgtgtctcc agggcagagg gccaccatca cctgcagagc cagtgagagt
      181 gtcagtgcct ttggaataag cctcattcac tggtatcaac agaaaccagg acaacctcct
      241 aaactcctga tttaccaagc aatcaataag gagactgggg tcccagccag gttcagcggc
      301 agtgggtctg ggaccgattt caccctcaca attaatcctg tggaacctga cgatggtgca
      361 gattattact gtctgcagag taagaattct ccgtggtcgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01003645             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20254:8233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003645
VERSION     KCVT01003645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20254:8233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81170.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          122 c          118 g          106 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattctga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcctg gatattgagg atggaaacac ctatttgcat tggtacctga agaagccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01003646             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:28752:10594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003646
VERSION     KCVT01003646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:28752:10594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81171.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003647             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:28331:11762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003647
VERSION     KCVT01003647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:28331:11762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81172.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          107 c          106 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctaatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggag
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003648             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13841:3120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003648
VERSION     KCVT01003648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13841:3120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81173.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtactg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003649             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22807:21367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003649
VERSION     KCVT01003649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22807:21367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81174.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          125 c          113 g           88 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccag cacaaacctg ggcaggctcc caagctcctc
      241 ctctatggtg catccaccag ggcctccggc atcccaggca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01003650             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17338:9922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003650
VERSION     KCVT01003650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17338:9922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81175.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          117 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acgcagactc
      121 catactccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc tcagacaggt
      301 tcagtggcaa tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggttga gatcaaacga g
//
LOCUS       KCVT01003651             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:25579:19079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003651
VERSION     KCVT01003651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25579:19079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..405
                     /note="immunoglobulin light chain variable region"
     V_region        63..405
     V_segment       63..365
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <342..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81176.1"
                     /translation="CMQALEFPPFTF"
     J_segment       368..405
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT           93 a          111 c          108 g           96 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct ggatccagtg
       61 gggacattgt gatgacccag actccactct ccctgcccgt cacccttgga gagccggcct
      121 ccatctcctg caggtctagt cagagcctct tggatagtga ggatggaaac acctatttgg
      181 aatggtacct gcagaagcca ggccagtctc cacagctctt gatttatgag gtttccaacc
      241 gggcctctgg agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga
      301 aaatcagcag agtggaggct gaggatgttg gggtttatta ttgcatgcaa gctctagagt
      361 ttcctccatt cactttcggc cccgggacca aactggagat caaacgag
//
LOCUS       KCVT01003652             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9955:20167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003652
VERSION     KCVT01003652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9955:20167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..387
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81177.1"
                     /translation="CLQSKNSPWSF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           98 a          116 c          115 g           99 t
ORIGIN      
        1 acatggggag cctctcgttc agctctcaga aatggggtcc tgggctcctt tcctgtggat
       61 cctcctgctc tgtgctccag gctgcagtgg ggacattgtg ctgacccagt ctccagcctc
      121 tttggccgtg tctccagggc agagggccac catcacctgc agagccagtg agagtgtcag
      181 tgcctttgga ataagcctca ttcactggta tcaacagaaa ccaggacaac ctcctaaact
      241 cctgatttac caagcaatca ataaggagac tggggtccca gccaggttca gcggcagtgg
      301 gtctgggacc gatttcaccc tcacaattaa tcctgtggaa cctgacgatg gtgcagatta
      361 ttactgtctg cagagtaaga attctccgtg gtcgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01003653             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14462:10339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003653
VERSION     KCVT01003653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14462:10339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81178.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcgc tcttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agtctcttgg ctagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaagtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagactttc cgctcacttt cggcggaggg
      421 accaaggtgg agctcaaacg ag
//
LOCUS       KCVT01003654             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:12433:14996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003654
VERSION     KCVT01003654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12433:14996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81179.1"
                     /translation="CLQSKNSPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g          100 t
ORIGIN      
        1 acatgggggc agcctctagt tcagctctca gaaatggggt cctgggctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggctgcaat ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accatcgtct gcagagccag tgagagtgtc
      181 aatgtctttg gaataaacct cattcactgg tatcagcaga aaccaggaca acctcctaaa
      241 cccctgattt accaagcatc caataaagaa actggggtcc cagccaggtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aagctgacga tgctgcagat
      361 tattactgtc tgcagagtaa gaattctccg tggacgtttg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01003655             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18537:20408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003655
VERSION     KCVT01003655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18537:20408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81180.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          126 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggca
      241 agtctccgca ggtcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc accgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003656             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11568:17884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003656
VERSION     KCVT01003656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11568:17884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81181.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtcaagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttgcact ggtacttgaa gaagccaggc
      241 cagtctccac aggtcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003657             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14802:17492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003657
VERSION     KCVT01003657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14802:17492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..237
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81182.1"
                     /translation="CQQYNSDPFTF"
     J_segment       238..275
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           78 a           70 c           66 g           64 t
ORIGIN      
        1 acatggggta accatcactt gtcgggcgag tcaggacata agaagttatt tagcgtggta
       61 tcagcagaaa ccaggcaaac ccccgaagcc cttgatctat tacgcatccg ttttggaaag
      121 tggggtccca tcaaggttca gtggcagtgg atctgggaca gaattcactc tcaccatcag
      181 cagtctgcag cctgaggatt ttgcaactta ttactgtcaa caatataaca gtgacccatt
      241 cactttcggc cccgggacca aactggatac caaacgag
//
LOCUS       KCVT01003658             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19808:18997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003658
VERSION     KCVT01003658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19808:18997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81183.1"
                     /translation="CQQYDNDPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          117 c          107 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacaatgac ccgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01003659             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17446:18269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003659
VERSION     KCVT01003659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17446:18269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81184.1"
                     /translation="CQQYNSLPLTF"
     J_segment       387..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          111 a          108 c          110 g           98 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacacagtca ccatcacttg ccgggcaagt
      181 caggacatta gcagatattt aaattggtat cagcagaaac cggggaaagc ccctaagttc
      241 ctaatctatt atgtaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggagag aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat
      361 tattgtcaac agtataatag tttaccgctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01003660             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5607:17218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003660
VERSION     KCVT01003660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5607:17218"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81185.1"
                     /translation="CQQGYGFPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          119 c          102 g          101 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcgcgatcac ttgcctggcg agtcaaggca
      181 ttggcaataa tttaaattgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 atacggcatc caatttacat ggtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc aacagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tggttttcca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01003661             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22606:9948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003661
VERSION     KCVT01003661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22606:9948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81186.1"
                     /translation="CYQYSSGYSF"
     J_segment       382..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           95 a          122 c          113 g           88 t
ORIGIN      
        1 acatgggggc tgctaggtta ggacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggtacc gccggacaag ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc cggggaaaga gccactctct cctgcagggc cagtcagagt
      181 gttagcagct atttagcctg gtaccagcaa aaacctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccagcagggc cactgccatc cctgacaggt tcagtggcag tgggtctggg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttggaat ttatcactgc
      361 tatcagtata gcagcgggta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01003662             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16880:2870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003662
VERSION     KCVT01003662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16880:2870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..363
                     /note="immunoglobulin light chain variable region"
     V_region        86..363
     V_segment       86..325
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81187.1"
                     /translation="CQQYKSLPFTF"
     J_segment       326..363
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT           95 a           97 c           93 g           81 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggag acagagtcac catcacttgc cgggcaagtc
      121 aggacattac cagtttttta aattggtatc agcagaaacc ggggaaggcc cctaagctcc
      181 tgatctattt tgaaaatcgt ctggaaagtg gggtcccgtc aaggttcggc ggcagtggat
      241 cagggacaga attcactctc accatcagca gcctgcaacc tgaggatttt gcaacttatt
      301 actgtcaaca gtataaaagt ttaccattca ctttcggccc cgggaccaaa ctggatatca
      361 aacgag
//
LOCUS       KCVT01003663             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15262:16116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003663
VERSION     KCVT01003663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15262:16116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81188.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           95 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003664             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9838:10843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003664
VERSION     KCVT01003664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9838:10843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81189.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc gggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01003665             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16039:11474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003665
VERSION     KCVT01003665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16039:11474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81190.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003666             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8054:11557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003666
VERSION     KCVT01003666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8054:11557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81191.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc attaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003667             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24287:14096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003667
VERSION     KCVT01003667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24287:14096"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81192.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc cccgacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003668             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:8240:12728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003668
VERSION     KCVT01003668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8240:12728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81193.1"
                     /translation="CIQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          121 c          116 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacctgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tacaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003669             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17804:17914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003669
VERSION     KCVT01003669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17804:17914"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81194.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01003670             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18959:11409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003670
VERSION     KCVT01003670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18959:11409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81195.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccggac ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003671             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21407:16242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003671
VERSION     KCVT01003671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21407:16242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81196.1"
                     /translation="CQQYDSDSLSF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          113 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tggagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcagtt ttggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003672             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:23626:4197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003672
VERSION     KCVT01003672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23626:4197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81197.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tataaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003673             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16236:15762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003673
VERSION     KCVT01003673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16236:15762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81198.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ccgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003674             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15024:5966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003674
VERSION     KCVT01003674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15024:5966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81199.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctctaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003675             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:21006:6456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003675
VERSION     KCVT01003675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21006:6456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81200.1"
                     /translation="CLQLKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          118 c          105 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagcttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003676             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16779:17117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003676
VERSION     KCVT01003676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16779:17117"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..439
                     /note="immunoglobulin light chain variable region"
     V_region        118..439
     V_segment       118..402
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81201.1"
                     /translation="CQQNSNWPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          103 a          128 c          122 g           89 t
ORIGIN      
        1 acatgggggg gtcagagctc tggggaggaa ctgctcagtt aggacccaga gggaaccatg
       61 gaagccccag cacagcttct cttcctcctg ctgctctggc tcccagatac caccggagaa
      121 atagtgatga cgcagtctcc agccaccctg tctttgtctc caggagaaag agccaccctc
      181 tcctgcaggg ccagtcagag tgtcagcagc agcttagcct ggtaccaaca aaaacctggg
      241 caggctccca ggctcctcat ctatggtgca tccagcaggg ccactggcat cccagacagg
      301 ttcagtggca gtgggtctgg gacagacttc actctcacca tcaccagcct ggagcctgaa
      361 gatgttgcag tctatttttg tcagcagaat agtaactggc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003677             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21221:17672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003677
VERSION     KCVT01003677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21221:17672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81202.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc cagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgacaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003678             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11648:12713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003678
VERSION     KCVT01003678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11648:12713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81203.1"
                     /translation="CQQYNSLPLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          106 a          109 c          108 g           98 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcatctct gggggacaga gtcaccatca cttgccgggc aagtcaggac
      181 attagcagat atttaaattg gtatcagcag aaaccgggga aagcccctaa gttcctgatc
      241 tattatgtaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattattgt
      361 caacagtata atagtttacc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01003679             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17088:13598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003679
VERSION     KCVT01003679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17088:13598"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81204.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003680             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20609:17656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003680
VERSION     KCVT01003680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20609:17656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81205.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagt agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003681             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16405:20152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003681
VERSION     KCVT01003681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16405:20152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81206.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003682             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:3925:13442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003682
VERSION     KCVT01003682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3925:13442"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81207.1"
                     /translation="CQQHYGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          119 c          106 g           91 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat tatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003683             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15033:6430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003683
VERSION     KCVT01003683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15033:6430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..350
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81208.1"
                     /translation="SMHDSGGPTTF"
     J_segment       376..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT           95 a          112 c          116 g           90 t
ORIGIN      
        1 acatggggga gcaccgcctg ccagcatgtt cttgggagtt caggtgcagc tcctctggag
       61 cctggctttc tggagggcag tgagtggaga catcatcctg aaccagacgc cagcatccct
      121 gactgcacct ccaggagaga cagtctccat ctcctgccaa gccagagcag atgtacatgg
      181 tgaaatgtct tggatccgga taaaccttga acaaagactt gaaccccttt tatctcatgt
      241 cactaccttg gccccaggtg tcgcagcccg gttcatcagc aaggggagtg gcaccagtta
      301 tgttttcagc atcagtgacc tgcagcctgg ggactctggg gactattact ccatgcatga
      361 ctctgggggg ccaaccactt tcggtggagg gaccaaggtg gagatcaaac gaa
//
LOCUS       KCVT01003684             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15290:16420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003684
VERSION     KCVT01003684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15290:16420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..438
                     /note="immunoglobulin light chain variable region"
     V_region        100..438
     V_segment       100..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81209.1"
                     /translation="CMQGLEYPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          116 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggaa tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgcggat ggaaaaacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtt tagagtatcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01003685             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21309:16316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003685
VERSION     KCVT01003685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21309:16316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..254
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81210.1"
                     /translation="CQQHDNSPRTF"
     J_segment       256..291
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>294
                     /gene="IGKC"
BASE COUNT           86 a           75 c           73 g           60 t
ORIGIN      
        1 acatgggatc tgtaggagac agagtcacca tcacttgcac agccagccac gatataaata
       61 tctggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg atctataggg
      121 catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct gggacagatt
      181 tcaccctcac catcagcggc ctgcagcctg aagatttcgc aacatattac tgtcaacagc
      241 atgataattc ccctcggacg ttcggccaag ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01003686             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19248:8975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003686
VERSION     KCVT01003686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19248:8975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81211.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          109 c          109 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcacggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcttccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taaggccctg
      241 atctattatg caaaccggtt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaatctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt agagatcaaa
      421 cgag
//
LOCUS       KCVT01003687             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16183:12985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003687
VERSION     KCVT01003687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16183:12985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81212.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          124 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003688             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9478:10722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003688
VERSION     KCVT01003688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9478:10722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81213.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          106 c          107 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003689             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15617:17881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003689
VERSION     KCVT01003689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15617:17881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..365
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81214.1"
                     /translation="CLQGYIDPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          112 c          111 g           98 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgactt ccagatgacc cagtctccat
      121 cttccctgtc tgcatcggtc ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcgattt tttaagttgg tatcagcaga aaccaggaaa acctcctaag cgcctgattt
      241 atgctgcatc cagtttgcaa agtggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcggct tattactgtc
      361 tacagggtta tattgacccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003690             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22034:7556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003690
VERSION     KCVT01003690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22034:7556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81215.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          124 c          118 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagcaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacg tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccacg gtggagatca
      421 aacgag
//
LOCUS       KCVT01003691             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:21633:14219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003691
VERSION     KCVT01003691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21633:14219"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..399
                     /note="immunoglobulin light chain variable region"
     V_region        78..399
     V_segment       78..352
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81216.1"
                     /translation="CQQHNGYPPTF"
     J_segment       365..399
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>402
                     /gene="IGKC"
BASE COUNT          100 a          112 c          102 g           88 t
ORIGIN      
        1 acatggggag catggacatg agggtccccg ctcagctcct ggggctcctg ctgctctggc
       61 tcccaggtgc cagatgtgac atccagatga cccagtctcc atcctccctg tctgcatctg
      121 taggagacac agtcaccatc acttgtcggg caagtcaggg cattacgaat gatttagcct
      181 ggtatcaaca gaaaccaggt aaagccccga agcccctgat ctattacgca tccaatttgg
      241 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc actctcacca
      301 tcagcagcct gcagcctgaa gattttgcaa cttattattg tcaacagcat aatggatacc
      361 ctccgacgtt cggccaaggg accagggtgg aaatcaaacg ag
//
LOCUS       KCVT01003692             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17578:11507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003692
VERSION     KCVT01003692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17578:11507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81217.1"
                     /translation="CMQSLELPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          122 c          116 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcgtccatc tcctgtaggt ctagtcagag
      181 cctcgtggat agtgaggatg gaaacaccta tttggaatgg ttcctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgacgtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagcttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01003693             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5035:7715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003693
VERSION     KCVT01003693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5035:7715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81218.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tttccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca ggctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01003694             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5965:7635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003694
VERSION     KCVT01003694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5965:7635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81219.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g          106 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca cacctcttga tttatgaagt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003695             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:27307:12484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003695
VERSION     KCVT01003695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:27307:12484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..379
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81220.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          125 c          112 g           85 t
ORIGIN      
        1 acatggggaa ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa attgtgctga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcaac agcttagcct ggtaccagca gaaacctggg caggctccca gactcctcat
      241 ctatggtgca tccaacaggg ccactggcat cccaggcagg ttcagaggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gatgttgcac tttattattg
      361 tcagcagaac agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003696             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:23034:7569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003696
VERSION     KCVT01003696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23034:7569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81221.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggggagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atctggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003697             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19829:10093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003697
VERSION     KCVT01003697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19829:10093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81222.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003698             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10335:5973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003698
VERSION     KCVT01003698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10335:5973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81223.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          126 c          118 g           89 t
ORIGIN      
        1 acatggtgag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac caacaaaaac ctgggcaggc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01003699             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:27151:8597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003699
VERSION     KCVT01003699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:27151:8597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..388
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81224.1"
                     /translation="CQQIHSNPFTF"
     J_segment       393..426
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g          104 t
ORIGIN      
        1 acatgggggg caggagtcag tctcagtcag gacacagcat ggacatgagg gtccctgctc
       61 agctcctggg gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc
      121 agtctccatc tgccttgtct gcatctgtgg gagacagagt caccgtctct tgccgggcaa
      181 gtcagaacat ttatagttat ttagcgtggt atcagcagaa accagggaaa gcccctaagc
      241 tcctgatata tgatgtatcc agattgcaga gtgggattcc ctctcggttc agcggcagtg
      301 gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaactt
      361 attactgtca acagattcat agtaacccat ttactttcgg ccccgggacc aaactggata
      421 tcaaacgag
//
LOCUS       KCVT01003700             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14058:11758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003700
VERSION     KCVT01003700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14058:11758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81225.1"
                     /translation="CQQGYNTPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          114 c          116 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 atattagcag ctggttagcc tggtatcagc tgaagccggg gaaagcccct aaactcttga
      241 tctataaggc gtccagtttg gcaagagggg tcccatcgag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcagtagcc tgcagcctga agattttgca acttattatt
      361 gtcaacaggg ttacaatacc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003701             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12682:15066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003701
VERSION     KCVT01003701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12682:15066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81226.1"
                     /translation="CMQARDFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           93 a          125 c          121 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccattggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttc gatagtgagg aaggaaacac ctatttggag tggtacctgc agaggccagg
      241 ccagtctcca caggtcttga tttatggggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaga atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tcgagacttt ccattcactt tcggccccgg
      421 gaccaaactg gacatcaaac gag
//
LOCUS       KCVT01003702             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7207:16249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003702
VERSION     KCVT01003702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7207:16249"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81227.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           93 a          121 c          124 g          108 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctga
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gagtggcacc tgcagaagcc
      241 aggccagtct ctacagctct tgatttatga ggtttcctac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt tctgcatgca ggctctagag tttcctctca ctttcggcgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01003703             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21693:12071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003703
VERSION     KCVT01003703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21693:12071"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..416
                     /note="immunoglobulin light chain variable region"
     V_region        97..416
     V_segment       97..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81228.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          111 c          100 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtggcatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgaaacatcc agtttggtaa gtggggtccc atcaaggttc agcggcagtg catctgggat
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcatctt attactgtct
      361 acagtataaa agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003704             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12375:6730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003704
VERSION     KCVT01003704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12375:6730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81229.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          117 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003705             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21108:4366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003705
VERSION     KCVT01003705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21108:4366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81230.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c           98 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacga gtcaaagtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagt tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggccgtg tatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagac tttgcaactt actactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01003706             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20575:12027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003706
VERSION     KCVT01003706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20575:12027"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81231.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttccaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagcgtgg aggctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003707             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15404:8336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003707
VERSION     KCVT01003707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15404:8336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..356
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81232.1"
                     /translation="SMHDSGGPTTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           95 a          114 c          118 g           92 t
ORIGIN      
        1 acatgggggg ctctgagcac cgcctgccag catgttcttg ggagttcagg tgcagctcct
       61 ctggagcctg gctttctgga gggcagtgag tggagacatc atcctgaacc agacgccagc
      121 atccctgact gcacctccag gagagacagt ctccatctcc tgccaagcca gagcagatgt
      181 acatggtgaa atgtcttgga tccggataaa ccttgaacaa agacttgaac cccttttatc
      241 tcatgtcact accttggccc caggtgtcgc agcccggttc atcagcaagg ggagtggcac
      301 cagttatgtt ttcagcatca gtgacctgca gcctggggac tctggggact attactccat
      361 gcatgactct ggggggccaa ccactttcgg tggagggacc aaggtggaga tcaaacgaa
//
LOCUS       KCVT01003708             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:4108:16822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003708
VERSION     KCVT01003708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4108:16822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..385
                     /note="immunoglobulin light chain variable region"
     V_region        72..385
     V_segment       72..356
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81233.1"
                     /translation="CLQYSESPLSF"
     J_segment       361..385
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>396
                     /gene="IGKC"
BASE COUNT           90 a          109 c          102 g           95 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagt tcctggggct cctgctgctc tggctcccag
       61 gtgccagatg tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag
      121 acacagtcac catcacttgc cgggcgagtc agactattcg cagttggtta aactggtttc
      181 aacagaagtc aggaaaagcc cctaaactcc tgatctatag ggcgtccatt ttacaaagtg
      241 gagtcccatc aaggttcagc ggcagtggat ctgggacaga tttcactctc accatcagca
      301 gcctgcaacc tgaagatttt gcgacttact tctgtctaca gtatagtgag agccctctct
      361 ctttcggcgg ggggaccaag gtggacatta gacgag
//
LOCUS       KCVT01003709             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14390:18612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003709
VERSION     KCVT01003709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14390:18612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81234.1"
                     /translation="CMQALDFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          123 c          122 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatgcagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gcggatgttg gggtttatta ctgcatgcaa gctctagact ttcccctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01003710             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10593:4861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003710
VERSION     KCVT01003710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10593:4861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81235.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          121 c          116 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaat agggccactg gcatctcaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003711             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17498:12737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003711
VERSION     KCVT01003711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17498:12737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..396
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81236.1"
                     /translation="CQQYDSDSLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          108 a          121 c          115 g           97 t
ORIGIN      
        1 acatggggag gcacgcttca tgcaggagtc agacccagtc aggacacagc atggacatga
       61 gggtccccgc tcagctccta ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca
      121 tccagatgac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
      181 cttgtcgggc gactcaggac attcgcagtt atttagcgtg gtatcagcag aaaccaggga
      241 aagccccgaa gcccttgatc tattacgcgt ccactttgga aagtggggtc ccatcaaggt
      301 tcagcggcag tggatctggg acagaattca ctctcaccat cagcagcctg cagcctgaag
      361 attttgcaac ttattactgt caacagtatg acagtgattc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003712             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10050:10520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003712
VERSION     KCVT01003712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10050:10520"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81237.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          117 c          114 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca gtttggaaag tggggtccca tcaaggttca gcggcggtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacccgtt cactttcggt ggagggacca aggtagacat
      421 caaacgag
//
LOCUS       KCVT01003713             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14425:14127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003713
VERSION     KCVT01003713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14425:14127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81238.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgtg gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgacg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003714             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20764:5091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003714
VERSION     KCVT01003714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20764:5091"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81239.1"
                     /translation="CMQALDFPYSF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          121 c          114 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt ttgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctaatttcac actgaaaatc agcagtgtgg aggctgagga
      361 tgttggggtc tattactgca tgcaagctct agactttcct tacagttttg gccaggggac
      421 cacagtggag attaaacgag
//
LOCUS       KCVT01003715             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14225:14508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003715
VERSION     KCVT01003715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14225:14508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81240.1"
                     /translation="CQQGHSYPWTF"
     J_segment       384..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>424
                     /gene="IGKC"
BASE COUNT           99 a          118 c          111 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca gtcgagtcta
      181 ggcattggca aatttttaaa ttggtatcag cagaaaccag ggaaagcccc caaactcctg
      241 atctataggg catccagttt gcaaactggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cgcttattac
      361 tgtcaacagg gtcatagtta cccgtggacc ttcggccaag ggaccaaggt ggagatgaaa
      421 cgag
//
LOCUS       KCVT01003716             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22593:18228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003716
VERSION     KCVT01003716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22593:18228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81241.1"
                     /translation="CQHSYGAPYSF"
     J_segment       383..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          103 a          113 c          110 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtgaga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctatgttga atccactttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga ggatgttgca acttattact
      361 gtcagcatag ttatggtgcc ccgtacagtt ttggccaggg gaccaaagtg gagatcatac
      421 gag
//
LOCUS       KCVT01003717             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20002:5207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003717
VERSION     KCVT01003717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20002:5207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81242.1"
                     /translation="CQQGYSYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          119 c          107 g           95 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgca ggagacacag tcaccatcac ttgccaggcg agtcaaggca
      181 ttggcaatac tttaaattgg tatcaacaga aaccggggaa agcccctaca ctcctgatct
      241 atagggcatc cggtttgcaa agtgggactc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttatccg tacagttttg gccaggggac caaactggag atcaaacgag
//
LOCUS       KCVT01003718             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15735:9771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003718
VERSION     KCVT01003718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15735:9771"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81243.1"
                     /translation="CQQYNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          119 c          109 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacc aatgatttag cctggtatca gcaaaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtgggtc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag tataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003719             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8683:9766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003719
VERSION     KCVT01003719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8683:9766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81244.1"
                     /translation="CMQALEFPYTF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          121 c          114 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagagtcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagac
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctcctcaa ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tacacttttg gccaggggac
      421 cacagtggag atcaaacgag
//
LOCUS       KCVT01003720             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24633:8889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003720
VERSION     KCVT01003720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24633:8889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81245.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccctcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003721             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15523:20842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003721
VERSION     KCVT01003721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15523:20842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..412
                     /note="immunoglobulin light chain variable region"
     V_region        102..412
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81246.1"
                     /translation="CLQGDTTPFTF"
     J_segment       392..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>426
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           96 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgattattta agttggtatc agcagaaacc gggaaaagct cctaagcgcc
      241 taatctatgc tgcctccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgagacagt gttcactctc accatcagca gcctgcagcc tgaagatttt gcgacttatt
      361 actgtctaca gggtgatact accccgttca cttttggcca ggggaccaaa gtagacgtca
      421 aacgag
//
LOCUS       KCVT01003722             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:17466:2631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003722
VERSION     KCVT01003722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17466:2631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..423
                     /note="immunoglobulin light chain variable region"
     V_region        90..423
     V_segment       90..387
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81247.1"
                     /translation="CMQGTQLLTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          117 c          113 g           96 t
ORIGIN      
        1 acatggggat caggactcct cagttcacca tgaggctccc tgctcagctc ctggggctgc
       61 tattgctctg cgtccccgga tccagtgggg atgttgtgat gactcagtct ccactctccc
      121 tgcccatcac ccctggacaa ccggcctcca tctcctgcag gtctagtcaa agccttctac
      181 acactgatgg gaaaacctac ttgaattggt atcagcagaa gccaggccaa cctccaaggc
      241 gcctaattta tcaggtttct aaccgggact ctggggtccc agacagattc agcggcagtg
      301 gggcagggac agatttcaca ctgaaaatca gcagagtgga gactgaggat gttggagttt
      361 attactgcat gcaaggtaca cagcttctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003723             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:26472:12436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003723
VERSION     KCVT01003723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:26472:12436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81248.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          106 t
ORIGIN      
        1 atggggtgac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cacaaaccag
      241 gccagtctcc agagctcttg atttatgagg tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gctttattac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggaggtcaaa cgag
//
LOCUS       KCVT01003724             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5131:18228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003724
VERSION     KCVT01003724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5131:18228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81249.1"
                     /translation="CMQALEFPWTF"
     J_segment       276..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           70 a           79 c           90 g           76 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagtctc
      121 cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctggagt ttccttggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01003725             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:9361:14340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003725
VERSION     KCVT01003725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9361:14340"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81250.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          116 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccca gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaacggggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01003726             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12473:16598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003726
VERSION     KCVT01003726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12473:16598"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..399
                     /note="immunoglobulin light chain variable region"
     V_region        97..399
     V_segment       97..380
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81251.1"
                     /translation="CQKYSSSPFTF"
     J_segment       381..399
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           84 a          120 c          105 g           90 t
ORIGIN      
        1 acatgggggc tgctcagtta ggacccagag agaaccatgg aaatcccagc tcagcttctc
       61 ttcctcctgc tactgtggct cccaggtacc accggacaag ttattttgac tcagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccaccctct cctgcagggc cagtcagagt
      181 gttggcagca gcttagcctg gtaccagcag aaacctgggc aggcccccag actcctcgtc
      241 tatggtgcat ccaggagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag attttgcagt gtattactgt
      361 cagaagtata gtagttcccc attcactttc ggccccggg
//
LOCUS       KCVT01003727             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22343:3708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003727
VERSION     KCVT01003727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22343:3708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..389
                     /note="immunoglobulin light chain variable region"
     V_region        50..389
     V_segment       50..352
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81252.1"
                     /translation="CMQTLEFPLTF"
     J_segment       353..389
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>392
                     /gene="IGKC"
BASE COUNT           83 a          102 c          113 g           94 t
ORIGIN      
        1 acatgggctc ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat
       61 gacccaggct ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag
      121 gtctagtcag agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca
      181 gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt
      241 cccagacagg ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt
      301 ggaggctgag gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt
      361 cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003728             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22789:5175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003728
VERSION     KCVT01003728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22789:5175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81253.1"
                     /translation="CMQALEFPWTF"
     J_segment       406..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          121 c          123 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccctgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctggagt ttccttggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01003729             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11361:3645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003729
VERSION     KCVT01003729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11361:3645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81254.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgttctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003730             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14022:14889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003730
VERSION     KCVT01003730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14022:14889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81255.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003731             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16729:15391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003731
VERSION     KCVT01003731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16729:15391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81256.1"
                     /translation="CQKYSSFPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          125 c          107 g           93 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacatg ggcaggcccc cagactcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagttg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagactttgc agtgtattac
      361 tgtcagaagt atagtagttt cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01003732             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15045:18539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003732
VERSION     KCVT01003732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15045:18539"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81257.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          111 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc agtttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccgtca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01003733             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24699:18284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003733
VERSION     KCVT01003733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24699:18284"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81258.1"
                     /translation="CQQYNTLPYSF"
     J_segment       388..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          109 a          111 c          110 g           97 t
ORIGIN      
        1 acatggggca ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag
      121 tctccatcct ccctgtctgc gtctgtagga gacacagtca ccattacttg ccgggcaagt
      181 cagggcatta gtagttattt gaattggtat caacagaagc cggggaaagc ccctaaggtc
      241 ctgatctatt atacaaaccg tttggaaagc ggggtcccat caaggttcag cggcagcgga
      301 tctgggacag aattcactct caccatcagt agcctgcaac ctgaggattt tgcaacttat
      361 tactgtcaac agtataatac tttaccatac agttttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01003734             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:24663:6475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003734
VERSION     KCVT01003734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24663:6475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-61"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81259.1"
                     /translation="CQQAYSYPQTF"
     J_segment       383..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT           96 a          116 c          110 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tgccagtaat ttaaattggt atcagcagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcgtcc agtttgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaggat tttgccactt atttctgtca
      361 acaggcttat agttaccctc aaactttcgg tggagggacc aaggtgggga tcacacgag
//
LOCUS       KCVT01003735             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17603:6304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003735
VERSION     KCVT01003735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17603:6304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81260.1"
                     /translation="CQQHDNSPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          119 c          114 g           90 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctctctg tatctgtagg agacagagtc accatcactt gcagagccag
      181 tcagggtgtt agcgactggt tggcctggta tcaacagaga ccagggaaag cccctaaact
      241 cctgatctat agggcgtcca atttggatac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgctacata
      361 ttactgtcaa cagcatgata attcccctcc gacgttcggc caagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01003736             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10042:18073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003736
VERSION     KCVT01003736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10042:18073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81261.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          124 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc ccagataggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01003737             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:7603:12671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003737
VERSION     KCVT01003737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7603:12671"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81262.1"
                     /translation="CQQYNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          120 c          107 g           89 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcccccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagta taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003738             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8784:12278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003738
VERSION     KCVT01003738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8784:12278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81263.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          121 c          126 g          103 t
ORIGIN      
        1 ccatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccgc agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgacttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003739             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18101:9650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003739
VERSION     KCVT01003739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18101:9650"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81264.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac tcgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01003740             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:27453:7060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003740
VERSION     KCVT01003740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:27453:7060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81265.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcgga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003741             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14579:9474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003741
VERSION     KCVT01003741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14579:9474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81266.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          110 a          115 c          102 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcctaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaaa gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gatatcaagc
      421 gag
//
LOCUS       KCVT01003742             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6830:15007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003742
VERSION     KCVT01003742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6830:15007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81267.1"
                     /translation="CQQHNNYSPTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          104 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccaccc
      121 tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag tcagggcatt
      181 agcaatgatt tagcctggta tcagctgaaa ccagggaaag ccccgaagcc cctgatctat
      241 tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagcataata attactctcc cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003743             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18995:16120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003743
VERSION     KCVT01003743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18995:16120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81268.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          106 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gtccctgagc tcctgatcta
      241 tgctgcatcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg ggtctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcacagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003744             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18258:9486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003744
VERSION     KCVT01003744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18258:9486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81269.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggtttagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003745             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7980:22041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003745
VERSION     KCVT01003745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7980:22041"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81270.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagcga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003746             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21936:5355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003746
VERSION     KCVT01003746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21936:5355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81271.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          121 c          125 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtcgagtcag
      181 agcctcttgg atggtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003747             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18371:13589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003747
VERSION     KCVT01003747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18371:13589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81272.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           93 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccagtttgg aaagtggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01003748             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16523:5355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003748
VERSION     KCVT01003748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16523:5355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81273.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003749             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19725:17563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003749
VERSION     KCVT01003749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19725:17563"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81274.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgaaga tggaaacacc tatttggagt ggtatctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01003750             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10367:15523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003750
VERSION     KCVT01003750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10367:15523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81275.1"
                     /translation="CQQYNSDPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          118 c          104 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaagcc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga attcactctc accatcacca gtctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      421 aacgag
//
LOCUS       KCVT01003751             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10695:20272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003751
VERSION     KCVT01003751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10695:20272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..391
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81276.1"
                     /translation="SMHDYGWPTTF"
     J_segment       401..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          104 a          119 c          118 g           97 t
ORIGIN      
        1 acatggggat gcctcatgca ctatccaggc tctgagcacc gcctgccagc atgttcttgg
       61 gagttcaggt gcagctcctc tggagcctgg ctttctggag ggcagtgagt ggagacatca
      121 tcctgaacca gacgccagca tccctgactg cacctccagg agagacagtc tccatctcct
      181 gccaagccag agcagatgta catggtgaaa tatcttggat ccggataaac cttgaacaaa
      241 gacttgaacc ccatttatct catgtcacta ccttggcccc aggtgtcgca gaccggttca
      301 tcagcaaggg gagtggcacc agttatgttt tcagcatcag tgacctgcag cctggggact
      361 ctggggacta ttactccatg catgactatg ggtggccaac cactttcggt ggagggacca
      421 aggtggagat caaacgaa
//
LOCUS       KCVT01003752             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13592:14106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003752
VERSION     KCVT01003752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13592:14106"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81277.1"
                     /translation="CQQYHSLPWTF"
     J_segment       383..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcatcat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aacctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta tcacagttta ccgtggacgt tcggccaagg gaccaaggtg gatgtcaaac
      421 gag
//
LOCUS       KCVT01003753             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8256:10497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003753
VERSION     KCVT01003753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8256:10497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81278.1"
                     /translation="CMQFLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggagtg gtacctgcgg aagccaggcc
      241 agtctccaca gctcctcatt tatgaggttt ccagccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgaattca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatttc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatgaaacga g
//
LOCUS       KCVT01003754             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:23672:6283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003754
VERSION     KCVT01003754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23672:6283"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81279.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcattga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgttggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003755             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20385:9667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003755
VERSION     KCVT01003755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20385:9667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81280.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003756             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16356:9211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003756
VERSION     KCVT01003756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16356:9211"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81281.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          119 c          106 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacaac ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01003757             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19736:13638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003757
VERSION     KCVT01003757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19736:13638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81282.1"
                     /translation="CMQPLDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcagc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaacctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003758             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15387:4041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003758
VERSION     KCVT01003758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15387:4041"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81283.1"
                     /translation="CQQYSSDPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          113 c          105 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga gtcaggacat
      181 tagaagttat ttagcgtggt atcagcagaa accaggaaaa gccccgaagg ccttgatcta
      241 ttacgcatcc attttagaga gtgcggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcgccatca gcagcctgca gtctgacgat tttgcaactt attactgtca
      361 acaatatagc agtgacccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003759             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23491:7127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003759
VERSION     KCVT01003759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23491:7127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81284.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcatc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003760             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6424:21495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003760
VERSION     KCVT01003760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6424:21495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81285.1"
                     /translation="CQQYTSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          121 c          105 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga ctgaggacgt
      181 tagcagtcat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttttgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgaggac tttgtaactt atcactgtca
      361 acagtacact agtttccccc tcaccttcgg ccccgggacc aaactggaaa tcaaacgag
//
LOCUS       KCVT01003761             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22200:12535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003761
VERSION     KCVT01003761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22200:12535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..428
                     /note="immunoglobulin light chain variable region"
     V_region        94..428
     V_segment       94..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81286.1"
                     /translation="CGQGTHLPPTF"
     J_segment       395..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           95 a          123 c          119 g           94 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg gggtgttgtg atgactcagt ctccactctc
      121 cctgcccatc acccctggac agccggcctc catctcctgt aggtctagtc aaagccttgt
      181 acacaccact ggaaacacat acttgagttg gtatcagcag aagccaggcc aacctccaag
      241 gcgcctactt tatgaggttt cttaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt
      361 ttattactgc gggcaaggta cacaccttcc tcccacgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01003762             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18270:5438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003762
VERSION     KCVT01003762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18270:5438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81287.1"
                     /translation="CQQYDSDPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagtcc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003763             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7010:9782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003763
VERSION     KCVT01003763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7010:9782"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81288.1"
                     /translation="CQQYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          103 a          112 c          110 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 gcagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01003764             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14587:18261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003764
VERSION     KCVT01003764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14587:18261"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81289.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagtagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01003765             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15534:11334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003765
VERSION     KCVT01003765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15534:11334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81290.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagggatcaa
      421 acgag
//
LOCUS       KCVT01003766             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14377:5775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003766
VERSION     KCVT01003766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14377:5775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81291.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcact ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003767             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16840:10303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003767
VERSION     KCVT01003767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16840:10303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81292.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gaggctgagg
      361 atgttgggct ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003768             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7297:9860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003768
VERSION     KCVT01003768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7297:9860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81293.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          110 c          107 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctccttctg tcggagacag agtcaccatc acttgccggg caagtcaggt
      181 cattaggagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aactcctgat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gactttggaa cttattactg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003769             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19989:10418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003769
VERSION     KCVT01003769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19989:10418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81294.1"
                     /translation="CLQGYSPPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          106 g           98 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtgggag acagagtcac tatcagttgc cgggcaagtc
      181 aggacattag cgattattta acttggtatc agcagaaacc aggaaaaact cctaagcgcc
      241 tgatctatgc tgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttttt
      361 actgtctaca gggttatagt cccccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01003770             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21542:12530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003770
VERSION     KCVT01003770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21542:12530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81295.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01003771             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12591:9601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003771
VERSION     KCVT01003771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12591:9601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81296.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaagat ggaaatacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca actgttgatt tatgaggttt ccaaccgggc ctctggagtt cccgataggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atccaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003772             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15274:8963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003772
VERSION     KCVT01003772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15274:8963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81297.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca cccttagaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaggccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003773             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6197:11754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003773
VERSION     KCVT01003773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6197:11754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81298.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagtgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003774             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7770:6914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003774
VERSION     KCVT01003774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7770:6914"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81299.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          116 c           99 g           97 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcagggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01003775             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:11830:10501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003775
VERSION     KCVT01003775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11830:10501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81300.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          125 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggtttc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01003776             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13047:18377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003776
VERSION     KCVT01003776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13047:18377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81301.1"
                     /translation="CMQSLDFPLTF"
     J_segment       404..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           94 a          123 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgc ggacattgtt atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccagccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgag aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcagt ctctagattt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaac cgag
//
LOCUS       KCVT01003777             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10924:16319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003777
VERSION     KCVT01003777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10924:16319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..429
                     /note="immunoglobulin light chain variable region"
     V_region        108..429
     V_segment       108..391
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81302.1"
                     /translation="CLQFKTFPYSF"
     J_segment       392..429
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           99 a          119 c          109 g          105 t
ORIGIN      
        1 acatgggggt ttgcaggagt cagacacagt caggacacag catggacatg agggcccccg
       61 ctcatctcct agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga
      121 ctcagtctcc atcttccctg tctgcatctg taggagacac tgtcaccatc tcttgccggg
      181 caagtcaggg tattagcagt tctttaagtt ggtttcagca gaaaccaggg aaagccccta
      241 agctcctcat ctatgctgca tccactttgg ccggtggggt cccatcaagg ttcagcggca
      301 gtggatctgg gacagacttc actctcacca tcagcagcct gcagcctgaa gattttgcaa
      361 cttattactg tctacagttt aaaactttcc cgtacagttt tggccagggg accaaagtgg
      421 agatcaaacg ag
//
LOCUS       KCVT01003778             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23509:9254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003778
VERSION     KCVT01003778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23509:9254"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..349
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81303.1"
                     /translation="CLQGDTAPFTF"
     J_segment       366..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           95 a          109 c          108 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc ttctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcttccc tgtctgcatc
      121 ggcaggagac agagtcacca tcacttgccg ggcaagtcag ggcattaacg attatttaag
      181 ttggtatcag cagaaaccag gaaaacctcc taagcgcctg atttatgctg catccagttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc agcttattac tgtctacagg gtgatactgc
      361 cccgttcact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003779             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17729:13482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003779
VERSION     KCVT01003779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17729:13482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81304.1"
                     /translation="CQHGYGIQLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggca gtcccagtca ggacacagca tggacatgag ggcccccact cagctcctgg
       61 ggttcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgtg ggagacagag tcaccatctc ttgccaggcg agtcaggaca
      181 ttagcaatga tttagcctgg tatcagcaga aaccgggaaa agcccctagg ctcctgatgt
      241 ataaggcatc cgctttgcag attggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc aacagcctgc agcctgaaga ttttgcaact tactactgtc
      361 aacatggtta tggtatccag ctcactttcg gtggagggac caaggtggac atcaaacgag
//
LOCUS       KCVT01003780             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6976:4022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003780
VERSION     KCVT01003780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6976:4022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..350
                     /note="immunoglobulin light chain variable region"
     V_region        11..350
     V_segment       11..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <290..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81305.1"
                     /translation="CMQALEFPWTF"
     J_segment       313..350
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>353
                     /gene="IGKC"
BASE COUNT           85 a           87 c          100 g           81 t
ORIGIN      
        1 acatgggggg gacattgtga tgacccagac tccactctcc ctgcccgtca cccttagaga
       61 gccggcctcc atctcctgca ggtctagtca gagcctcttg gatagtgagg atggaaacac
      121 ctatttggaa tggtacctac agaggccagg ccagtctcca cagctcttaa tttatgaggt
      181 ttcctaccgg gcctctggag tcccagagag gttcagtggc agtgggtcag acactgattt
      241 cacactgaaa atcagcagag tggaggctga ggatgttggg gtttattact gcatgcaagc
      301 tctagaattt ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003781             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16106:17582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003781
VERSION     KCVT01003781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16106:17582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81306.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          115 c           98 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt atacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01003782             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21547:18119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003782
VERSION     KCVT01003782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21547:18119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81307.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          113 c          108 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacta tcacttgccg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcag cagaaaccag gaaaagcccc gaaggccttg
      241 atctattacg catccatttt agagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg acgattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003783             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13987:19045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003783
VERSION     KCVT01003783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13987:19045"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..438
                     /note="immunoglobulin light chain variable region"
     V_region        101..438
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81308.1"
                     /translation="CMQSLDFPLTF"
     J_segment       403..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          108 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtta tgacccagac
      121 tccattctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcctg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccaggcag
      301 gttcagtggc agtgggtcag acacagattt cacactgaaa atcagcagag tggagactga
      361 ggatgttggg gtttattact gcatgcagtc tctagatttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaatc gag
//
LOCUS       KCVT01003784             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22587:18473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003784
VERSION     KCVT01003784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22587:18473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81309.1"
                     /translation="CQQYNNDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          112 c          113 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagaa gttatttagc gtggtatcag atgagaccag ggaaagcccc gagggcctta
      241 atctattacg cgaccatttt ggaaggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcggcagc ctgcagcctg aggattttgc aacttatttc
      361 tgtcaacagt ataacaatga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003785             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:4744:8403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003785
VERSION     KCVT01003785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:4744:8403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81310.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtct ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003786             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15438:20492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003786
VERSION     KCVT01003786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15438:20492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81311.1"
                     /translation="CLQGYIIPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          109 c          112 g          101 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgttcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tggaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ttgtctacag ggttatatta tcccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003787             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15706:2120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003787
VERSION     KCVT01003787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15706:2120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81312.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc cgctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003788             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:4300:13961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003788
VERSION     KCVT01003788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4300:13961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81313.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 gcagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01003789             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8566:21945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003789
VERSION     KCVT01003789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8566:21945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..424
                     /note="immunoglobulin light chain variable region"
     V_region        85..424
     V_segment       85..386
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81314.1"
                     /translation="CMQALEFPYSF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           93 a          114 c          118 g          102 t
ORIGIN      
        1 acatgggcag gtcaccttct cacaatgagg ctccctgctc agctcctggg actgctattg
       61 ctctggctcc ctggatccac tggggacatt gtgatgaccc agactccact ctccctgccc
      121 gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct catggatagt
      181 ggggatgtaa acacctattt ggaatggtac ctgcagaagc caggccagtc tccacatctc
      241 ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag tggcagtggg
      301 tcagacacgg atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat
      361 tactgcatgc aagctctaga gtttccgtac agttttggcc aggggaccag agtggagatc
      421 aaacgag
//
LOCUS       KCVT01003790             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20347:3815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003790
VERSION     KCVT01003790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20347:3815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81315.1"
                     /translation="CMQNTEDPTF"
     J_segment       399..429
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>435
                     /gene="IGKC"
BASE COUNT          101 a          119 c          110 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatactctgg gtccctgggt ccagtgggga tattgtgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga aacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacgtct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaagatg
      361 ttggtgttta ttattgcatg caaaatacag aagatcccac tttcggcccc gggaccaaac
      421 tggatatcat acgag
//
LOCUS       KCVT01003791             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21009:17281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003791
VERSION     KCVT01003791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21009:17281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81316.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc agcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctgttgat ttatgaggtt tccatccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aattcaaacg ag
//
LOCUS       KCVT01003792             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18510:17445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003792
VERSION     KCVT01003792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18510:17445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81317.1"
                     /translation="CQQHDNAPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          114 g           84 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc cgcagcctga agatatcgca acatattact
      361 gtcagcagca tgacaatgcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003793             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22054:9223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003793
VERSION     KCVT01003793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22054:9223"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81318.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          113 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga t
//
LOCUS       KCVT01003794             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15339:5366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003794
VERSION     KCVT01003794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15339:5366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81319.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01003795             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23768:10660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003795
VERSION     KCVT01003795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23768:10660"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81320.1"
                     /translation="CMQGLEFPITF"
     J_segment       402..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          121 c          115 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcca atcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01003796             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11554:12824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003796
VERSION     KCVT01003796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11554:12824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81321.1"
                     /translation="CMQYRHIPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          115 g          109 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagact
      121 ccattctccc tgtccgttag ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttga atagtgaaga cggaaacacc tatttggatt ggtacctgca gaggccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttaacagagt ggaggctgag
      361 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01003797             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14093:6309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003797
VERSION     KCVT01003797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14093:6309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81322.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003798             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18680:6841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003798
VERSION     KCVT01003798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18680:6841"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81323.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caatggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ccagtcagag
      181 cctcctggat agtgaagatg gaaacaccta tttggagtgg tatctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01003799             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8014:5103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003799
VERSION     KCVT01003799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8014:5103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81324.1"
                     /translation="CHQYNNLPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          114 c          102 g           97 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacatt tatttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctgat
      241 ctattatgca aatcgtttgg aaactggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcaacagcct gcaacccgaa gattttgcaa cttattactg
      361 tcaccagtat aataatttac cactcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003800             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22149:2361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003800
VERSION     KCVT01003800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22149:2361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81325.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          108 c          107 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacaat cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gccccaaagt tcctgatcta
      241 ttatgcaaat cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca agctgaagat tttgccactt attattgtca
      361 acaatataac agtttaccgt acagtttcgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003801             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18824:14295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003801
VERSION     KCVT01003801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18824:14295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81326.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          112 c          116 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tctccatctc ctgccaagcc agagcagatg
      181 tacatggtga aatatcttgg atccggataa accttgaaca aagacttgaa ccccatttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagaccggtt catcagcaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01003802             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16873:11724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003802
VERSION     KCVT01003802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16873:11724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81327.1"
                     /translation="CQQHDNSPPTF"
     J_segment       243..277
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           76 a           71 c           74 g           59 t
ORIGIN      
        1 acatggggag tcaccatcac ttgcagagcc agtcagggtg ttagcgactg gttggcctgg
       61 tatcaacaga gaccagggaa agcccctaaa ctcctgatct atagggcgtc caatttggat
      121 acaggggtcc catcaaggtt cagtggaagt ggatctggga cagatttcac tctcaccatc
      181 agcagcctgc agcctgaaga tatcgctaca tattactgtc aacagcatga taattcccct
      241 ccgacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003803             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22000:13230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003803
VERSION     KCVT01003803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22000:13230"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81328.1"
                     /translation="CMQGTQLPYSF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcaactc
       61 ctggggctac tggtgctctg gctccctggg accagtggag atattgtgat gacccagact
      121 ccactctccc tacccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctccttc atagtgatgg atccacctat ttggactggt acctgcagaa gccaggccag
      241 tctccacagc tcttgatcta tttgggttcc aaacgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gtcgggtgga ggctgaggat
      361 gttggggttt attactgcat gcaaggtaca cagcttccgt acagttttgg ccaggggacc
      421 aaagtggaga tcaaacgag
//
LOCUS       KCVT01003804             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:10161:13886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003804
VERSION     KCVT01003804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10161:13886"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81329.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003805             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15199:4048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003805
VERSION     KCVT01003805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15199:4048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81330.1"
                     /translation="CMQAREFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          127 c          113 g          103 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggagg ggaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgctggggtt tattactgca tgcaagctcg agagtttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01003806             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:9366:20662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003806
VERSION     KCVT01003806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9366:20662"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..256
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <234..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81331.1"
                     /translation="CMQALDFPWTF"
     J_segment       257..294
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>297
                     /gene="IGKC"
BASE COUNT           72 a           67 c           88 g           70 t
ORIGIN      
        1 acatgggggc ctccatctcc tgtaggtcta gtcagagcct cttggatagt gaggatggaa
       61 acacctattt ggaatggtac ctgcagaagc caggccagtc tccacaactc ttgatttatg
      121 aagtttccga ccgggcctct ggagtcccag acaggttcag tggcagtggg tcagacactg
      181 atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat tactgcatgc
      241 aagctctgga ctttccgtgg acgttcggcc aagggaccaa ggtggaagtc aaacgag
//
LOCUS       KCVT01003807             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25069:8270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003807
VERSION     KCVT01003807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25069:8270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81332.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          119 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003808             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21869:20255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003808
VERSION     KCVT01003808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21869:20255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81333.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggaatg gcgcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003809             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18700:8147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003809
VERSION     KCVT01003809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18700:8147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81334.1"
                     /translation="CLQFKTYPNSF"
     J_segment       385..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           95 a          118 c          108 g          102 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct cagctcctca
      241 tctatgctgc atccagtttg gccggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt ctctctcacc atcaccagcc tgcagcctga agattttgca acttatttct
      361 gtctgcagtt taaaacttac ccgaacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003810             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17916:2304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003810
VERSION     KCVT01003810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17916:2304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..387
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81335.1"
                     /translation="CLQSKNSPWSF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           96 a          116 c          116 g          100 t
ORIGIN      
        1 acatggggag cctctagttc agctctcaga aatggggtcc tgggctcctt tcctgtggat
       61 cctcctgctc tgtgctccag gctgcactgg ggacattgtg ctgacccagt ctccagcctc
      121 tttggccgtg tctccagggc agagggccac cttcacctgc agagccagtg ggagtgtcag
      181 tgcctttgga ataagcctca ttcactggta tcagcagaaa ccaggacaac ctcctaaact
      241 cctgatttat caagcaagca ataaggagac tggggtccca gccaggttca gcggcagtgg
      301 gtctgggacc gatttcaccc tcacaattaa tcctgtggaa cctgacgatg ctgcagatta
      361 ttactgtctg cagagtaaga attctccgtg gtcgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01003811             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5756:9327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003811
VERSION     KCVT01003811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5756:9327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81336.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003812             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10063:10261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003812
VERSION     KCVT01003812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10063:10261"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81337.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcgtgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc acattggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003813             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8453:20311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003813
VERSION     KCVT01003813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8453:20311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81338.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          114 c          109 g           96 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtctactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactttcacc atcaacagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003814             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10494:9672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003814
VERSION     KCVT01003814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10494:9672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81339.1"
                     /translation="CQQGYSFPFTF"
     J_segment       386..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           95 a          123 c          108 g           99 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgtaggaga cacagtcacg atcacttgcc aggcgagtca
      181 aggcattggc agtagtttaa gctggtatca gcagaaacca gggaaagccc ctaacctcct
      241 gatctttagg gcatccagtt tgcaaagtgg gattccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcagcag cctccagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatagtt tccccttcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01003815             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7607:14345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003815
VERSION     KCVT01003815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7607:14345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..455
                     /note="immunoglobulin light chain variable region"
     V_region        116..455
     V_segment       116..417
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <395..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81340.1"
                     /translation="CMQALEFPLTF"
     J_segment       418..455
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>458
                     /gene="IGKC"
BASE COUNT          101 a          123 c          127 g          107 t
ORIGIN      
        1 acatgggaac gcagagtaca tgggggatca cgactcctca ggtcaccttc tcacaatgag
       61 gctccctgct cagctcctgg gactgctaat gctctggctc cctggatcca atggggacat
      121 tgtgatgacc cagactccgc tctccctgcc cgtcatcctt ggagagccgg cctccctatc
      181 ctgcacgtct agtcagagcc tcttggatag tgaggatgga aacacctatt tggattggta
      241 cctgcagaag ccaggccagt ctccacagct cttgatttat gaggtttcca accgggcctc
      301 tggagtccca gacaggttca gtggcagtgg gtcagacact gatttcacac tgaaaatcag
      361 cagagtggag gctgaggatg ttggggttta ttactgcatg caagctctag agtttccgct
      421 cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01003816             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17439:6228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003816
VERSION     KCVT01003816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17439:6228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81341.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat caccagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01003817             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14016:13435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003817
VERSION     KCVT01003817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14016:13435"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81342.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           94 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003818             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20288:12879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003818
VERSION     KCVT01003818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20288:12879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81343.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003819             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14586:16770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003819
VERSION     KCVT01003819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14586:16770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..399
                     /note="immunoglobulin light chain variable region"
     V_region        78..399
     V_segment       78..361
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81344.1"
                     /translation="CQQYDSDPFTF"
     J_segment       364..399
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>402
                     /gene="IGKC"
BASE COUNT           97 a          110 c          104 g           91 t
ORIGIN      
        1 acatgggcag catggacatg agggtccccg ctcagctcct aggactcctg ctgctctgtc
       61 tcccaggtgc caaatgtgac atccagatga cccagtctcc atcctccctg tctgcatctg
      121 taggagacag agtcaccatc acttgtcggg cgagtcaggg cattcgcagt tatttagcgt
      181 ggtatcagca gaaaccaggg aaagccccga agcccttgat ctattacgcg tccactttgg
      241 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca
      301 tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagtat gacagtgacc
      361 cgttcacttt cggtggaggg accaaggtag agatcaaacg ag
//
LOCUS       KCVT01003820             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11184:14720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003820
VERSION     KCVT01003820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11184:14720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81345.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcgatgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01003821             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15351:15248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003821
VERSION     KCVT01003821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15351:15248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81346.1"
                     /translation="CMQALEFPWTF"
     J_segment       407..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           98 a          121 c          121 g          106 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gattggtacc tgcagaagcc
      241 aggccagtct ccacacctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagag tttccttgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01003822             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18872:14051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003822
VERSION     KCVT01003822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18872:14051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81347.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattatgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01003823             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:5797:4331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003823
VERSION     KCVT01003823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5797:4331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81348.1"
                     /translation="CQQYNSLPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          117 c          106 g          103 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gagattcaga tgacccagtc
      121 tccatcctcc ctgtctgcct ctgtcggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagt gtttatttaa attggtatca gcagaaaccg gggcaagccc ctaaactcct
      241 gatttatttt gcatcccgtt tggagaatgg ggtcccatca aggttcagcg gctctggatc
      301 tgggacagaa ttcagtctca ccatcagcag cctgcaacct gaagattctg cagcttattt
      361 ctgtcagcag tataatagtt taccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01003824             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13703:6434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003824
VERSION     KCVT01003824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13703:6434"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..297
                     /note="immunoglobulin light chain variable region"
     V_region        143..297
     V_segment       143..259
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81349.1"
                     /translation="CMQALEFPLTF"
     J_segment       260..297
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           66 a           81 c           84 g           69 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgagatg acccagactc
      121 cactctccct gcccgtcacc cttggagtcc cagacaggtt cagtggcagt gggtcagaca
      181 ctgatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca
      241 tgcaagctct agagtttccg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003825             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24548:7054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003825
VERSION     KCVT01003825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24548:7054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81350.1"
                     /translation="CMQSIKDPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          101 a          120 c          111 g          107 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tctagtgggg atattgtgat gacccagacc
      121 ccactctcgg tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctcc atagtaatgg agacacctat ttacattggt accttcagag gtcaggccag
      241 tctccacggc tcctgatcta taaagtaacc aatcggctac ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 attggtgttt atttctgcat gcaaagtata aaagatccat tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01003826             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5616:17428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003826
VERSION     KCVT01003826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5616:17428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..427
                     /note="immunoglobulin light chain variable region"
     V_region        93..427
     V_segment       93..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81351.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g           95 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg ggtgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgtc
      181 cacatcaatg gaaacacata cttgagttgg tatcagcaga acccaggcca acctccaagg
      241 cgcctaattt atgaggtttc tatccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agtagagtgg aggctgagga tgttggactt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01003827             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:10949:6150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003827
VERSION     KCVT01003827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10949:6150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81352.1"
                     /translation="CQQYNSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtcaattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003828             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18048:5233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003828
VERSION     KCVT01003828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18048:5233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81353.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacta gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003829             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5416:10786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003829
VERSION     KCVT01003829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5416:10786"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81354.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          103 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctt ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gtctgaagat tttgcaactt attactgtca
      361 acaacataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003830             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:9422:6084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003830
VERSION     KCVT01003830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9422:6084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..365
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81355.1"
                     /translation="CLQGYIIPYNF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          110 c          109 g           99 t
ORIGIN      
        1 acatggggca gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cttccctgtc tgcatcggta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcgattt tttaagttgg tatcagcaga aaccaggaaa acctcctaag cgcctgattt
      241 atgctgcatc cagtttggaa agtggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcggct tattattgtc
      361 tacagggtta tattatcccg tacaattttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003831             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16984:18499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003831
VERSION     KCVT01003831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16984:18499"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..298
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81356.1"
                     /translation="CQQYNSIPYSF"
     J_segment       307..344
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           93 a           86 c           85 g           83 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gctgacgcag tctccatcct ccctgtctgc
       61 atctgtagga gacagagtca ccatcacttg ccgggcgagt cagggcatta acatttattt
      121 aagttggtat cagcagaaac cagggaaagc ccctaagccc ctgatctatt atgcatccag
      181 tttggaaaca ggggtaccat caaggttcag tgggagtgga tctgggacag attatactct
      241 caccatcagc agtctgcagc ctgaagatat tgcaacatat tactgtcaac agtataattc
      301 tatcccgtac agttttggcc aggggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01003832             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7966:17753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003832
VERSION     KCVT01003832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7966:17753"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81357.1"
                     /translation="CQQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          113 a          108 c          103 g           99 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tgggactcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtat ttatttaaat tggtatcaac aaaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcaac atcaacagcc tgcaacctga agattttgca agttattact
      361 gtcaacagta taatagttta ccgtacactt ttggccacgg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003833             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14070:13484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003833
VERSION     KCVT01003833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14070:13484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81358.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacaac
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003834             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:15090:6358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003834
VERSION     KCVT01003834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15090:6358"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81359.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcattccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003835             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21294:16696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003835
VERSION     KCVT01003835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21294:16696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..440
                     /note="immunoglobulin light chain variable region"
     V_region        104..440
     V_segment       104..402
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81360.1"
                     /translation="CLQDIQFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           91 a          123 c          122 g          107 t
ORIGIN      
        1 acatgggggg actgatcagg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctgggg ctgctggtgc tctggctccc tgggaccagt ggggatattg tgttgactca
      121 gactccagtc tccctgtccg tcacccctgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc cttcaaacta atggaaacac ctatttgttt tggtacctgc agaagccagg
      241 ccagtctcca caactcctga tctacttggg ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag gcactgattt cacactgaaa atcagccggg tggaggctga
      361 agatgttggg gtttattact gcttgcaaga tatacagttt ccgctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01003836             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19851:7386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003836
VERSION     KCVT01003836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19851:7386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81361.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          116 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01003837             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20492:2775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003837
VERSION     KCVT01003837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20492:2775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81362.1"
                     /translation="CQQHADSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          118 c          110 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcaactgg ttggcctggt atcagcagag accagggaaa gcccctaagg tcctgatcta
      241 taggacatcc aatttggaaa caggggtccc atcaaggttc agtggaaccg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgct gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003838             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10023:4555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003838
VERSION     KCVT01003838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10023:4555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81363.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          113 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcccttgat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003839             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22445:18155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003839
VERSION     KCVT01003839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22445:18155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..414
                     /note="immunoglobulin light chain variable region"
     V_region        101..414
     V_segment       101..385
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81364.1"
                     /translation="CLQYSESPLSF"
     J_segment       390..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>425
                     /gene="IGKC"
BASE COUNT           99 a          117 c          111 g           98 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgcc gggcgagtca
      181 gactattcgc agttggttaa actggtttca acagaagtca ggaaaagccc ctaaactcct
      241 gatctatagg gcgtccattt tacaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcaacct gaagattttg cgacttactt
      361 ctgtctacag tatagtgaga gccctctctc tttcggcggg gggaccaagg tggacattag
      421 acgag
//
LOCUS       KCVT01003840             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19798:13863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003840
VERSION     KCVT01003840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19798:13863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81365.1"
                     /translation="CIQGSHLPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          118 c          115 g          100 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cgggtccagt ggggatattg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acaatcggcc tccatttcct gcaggtctag tcaaagcctt
      181 gtccacagtg atgggaatac ctacttgaat tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctat tttatcaggt ctctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgatgga
      361 atttattact gcatacaagg ttcacacctt ccgtacagtt ttggccaggg gaccgaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01003841             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5440:11436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003841
VERSION     KCVT01003841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5440:11436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81366.1"
                     /translation="CQQYNSLPWTF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          106 a          110 c          112 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcagttat ttaaattggt atcaacagaa accggggaaa gcccctaaag tcctgatgta
      241 ttacacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcacg ctcaccatca gcagcctgca acctgaggat tttgcaacct attactgtca
      361 gcagtataat agtttaccgt ggacgttcgg ccaagggacc aaggtggata tcaagcgag
//
LOCUS       KCVT01003842             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19637:9991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003842
VERSION     KCVT01003842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19637:9991"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81367.1"
                     /translation="CQQHNAYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          116 c          106 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcagctgtag gaaacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat gcttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003843             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16952:6586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003843
VERSION     KCVT01003843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16952:6586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81368.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac cctcggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggag tttattactg catgcaagct ctagaatttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003844             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:25990:8830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003844
VERSION     KCVT01003844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25990:8830"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81369.1"
                     /translation="CQQHNGYPPTF"
     J_segment       381..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          107 a          119 c          103 g           89 t
ORIGIN      
        1 acatgggaga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag tcagggcatt
      181 acgaatgatt tagcctggta tcaacagaaa ccaggtaaag ccccgaagcc cctgatctat
      241 tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gatttcactc tcaccatcag caccctgcag cctgaagatt ttgcaactta ttattgtcaa
      361 cagcataatg gataccctcc gacgttcggc caagggacca gggtggaaat caaacgag
//
LOCUS       KCVT01003845             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11586:4095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003845
VERSION     KCVT01003845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11586:4095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81370.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttc ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003846             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13584:18440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003846
VERSION     KCVT01003846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13584:18440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81371.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggca gacccagtca ggacacagct ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003847             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13150:12883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003847
VERSION     KCVT01003847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13150:12883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81372.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgacgtct ccacccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003848             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9194:3643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003848
VERSION     KCVT01003848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9194:3643"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81373.1"
                     /translation="CQQYNSSPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          114 c          102 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccg agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtagcccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003849             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10379:10048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003849
VERSION     KCVT01003849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10379:10048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81374.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          117 c          110 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 aggatattaa cacctggttg gcctggtatc aacagaagcc agggaaagcc cctaaggtcc
      241 tgatctatag gacatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcaaca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003850             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17108:16637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003850
VERSION     KCVT01003850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17108:16637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81375.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagag atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003851             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15941:6980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003851
VERSION     KCVT01003851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15941:6980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81376.1"
                     /translation="CQQYNSLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          109 c          108 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gatatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagttcctg
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattat
      361 tgtcaacagt ataatagttt accgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003852             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20153:5612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003852
VERSION     KCVT01003852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20153:5612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81377.1"
                     /translation="CLQGYNTPYNF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          112 c          110 g           94 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagttgacc cagtctccat
      121 cttccctgtc tgcatcggta ggagacagag tcaccatcac ctgccgggca agtcaggaca
      181 ttagcgatta tttaagttgg tatcagcaga aaccaggaaa agctcctaag cgcctgatct
      241 atgctgtgtc cagtttggaa ggtggggtcc catcaagatt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga tcttgcgact tattactgtc
      361 tacagggtta taataccccg tacaattttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01003853             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:3399:15644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003853
VERSION     KCVT01003853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:3399:15644"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81378.1"
                     /translation="CLHYNSDPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          109 a          108 c          108 g          103 t
ORIGIN      
        1 acatgggggt agaagttaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatct tccctgtctg catctgtaag agacagagtc accttcactt gcagggcaag
      181 tcagggcatt acaacttttt taaattggtg tcagcagaaa tcaggaaaaa ctcctaagcg
      241 cctgatctgt gttgaataca gtttggaaag tggggtccca tcaaggttca gtggcagtgg
      301 atctgggaca ggtttcactc tcaccatcag cagcctgcag cctgaagatt ttacaactta
      361 ttcctgtctt cattataaca gtgacccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01003854             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9011:3402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003854
VERSION     KCVT01003854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9011:3402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81379.1"
                     /translation="CQQYNSFPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          115 c          107 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacgtgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cacttgaccc agtctccatc
      121 ctccctgtct gcttctctag gagacagagt caccctctct tgccgggcaa gtcagggcgt
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaacc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agttttcctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003855             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15886:12797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003855
VERSION     KCVT01003855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15886:12797"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81380.1"
                     /translation="CQQHNTYPLTF"
     J_segment       390..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          118 c          105 g           94 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 aggacattag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatgtatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaagttatt
      361 actgtcaaca gcataatact tacccattga ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01003856             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20786:6246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003856
VERSION     KCVT01003856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20786:6246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81381.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          109 c          102 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcaattat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatgtaaac catttggaaa gtggggtccc atcaacgttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctcca acctgaagat tttgcaactt attactgtca
      361 acaatataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003857             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10206:10163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003857
VERSION     KCVT01003857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10206:10163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81382.1"
                     /translation="CQQHADSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          119 c          105 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataattgg ttggcctggt atcaacagaa accaggaaaa gcccctaacc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgct gattcccctc ggacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003858             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7248:3520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003858
VERSION     KCVT01003858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7248:3520"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81383.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggataga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003859             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15011:2227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003859
VERSION     KCVT01003859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15011:2227"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81384.1"
                     /translation="CMQALDFPYSF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          115 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgtactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt ttgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctaatttcac actgaaaatc agcagtgtgg aggctgagga
      361 tgttggggtc tattactgca tgcaagctct agactttcct tacagttttg gccaggggac
      421 cacagtggag attaaacgag
//
LOCUS       KCVT01003860             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19204:11226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003860
VERSION     KCVT01003860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19204:11226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81385.1"
                     /translation="CQQYNSLPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          110 c          106 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgtcag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagtttt ttaaattggt atcagcagaa accggggaaa gcccctaatc tcctgatcta
      241 ttatgcaaac cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataat agtttacctc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003861             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13172:19142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003861
VERSION     KCVT01003861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13172:19142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81386.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacg catggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggc ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003862             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10013:12145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003862
VERSION     KCVT01003862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10013:12145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..364
                     /note="immunoglobulin light chain variable region"
     V_region        87..364
     V_segment       87..317
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81387.1"
                     /translation="CQQHNGYPPTF"
     J_segment       330..364
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           97 a          100 c           95 g           75 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccagga gacacagtca ccatcacttg tcgggcaagt
      121 cagggcatta cgaatgattt agcctggtat caacagaaac caggtaaagc cccgaagccc
      181 ctgatctatt acgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      301 tattgtcaac agcataatgg ataccctccg acgttcggcc aagggaccag ggtggaaatc
      361 aaacgag
//
LOCUS       KCVT01003863             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21500:12276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003863
VERSION     KCVT01003863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21500:12276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81388.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct acttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tggagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003864             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17361:9698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003864
VERSION     KCVT01003864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17361:9698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81389.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          108 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt ccctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003865             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11223:7000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003865
VERSION     KCVT01003865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11223:7000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..375
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81390.1"
                     /translation="CQQGNTSPWTF"
     J_segment       384..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctacatct ataggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcac ttatttaaat tggtatcagc agaaaccggg gaaagcccct actctcctga
      241 tcttttatac aaacattttg gcaggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatacttct ccttggacct tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01003866             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17077:13440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003866
VERSION     KCVT01003866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17077:13440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81391.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccagtgg ggacattgtg ttgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 atagcctctt ggatggtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003867             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11686:6378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003867
VERSION     KCVT01003867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11686:6378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81392.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac aatgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003868             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9598:17672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003868
VERSION     KCVT01003868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9598:17672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81393.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgtt gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcat
      181 agcctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003869             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14854:5417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003869
VERSION     KCVT01003869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14854:5417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81394.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc atcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaaaatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003870             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12495:14484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003870
VERSION     KCVT01003870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12495:14484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81395.1"
                     /translation="CMQTLEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           92 a          119 c          123 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc ggtggggaca ttgtgatgac ccaggctcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggatg gtgaggatgg aaacacctat ttggattggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaaactcta gagtttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01003871             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20473:9257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003871
VERSION     KCVT01003871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20473:9257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81396.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          123 c          110 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01003872             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21668:11887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003872
VERSION     KCVT01003872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21668:11887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81397.1"
                     /translation="CQQYYTLCTF"
     J_segment       385..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          113 c          104 g          101 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg cccagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtcac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagtagt tttttaaatt ggtatcaaca gaagccgggg aaagccccta aggtcctcat
      241 ctattctgca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagttccct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagtat tatactttat gcacttttgg ccaggggacc acagtggaga tcaaacgag
//
LOCUS       KCVT01003873             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11801:14248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003873
VERSION     KCVT01003873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11801:14248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..257
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <235..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81398.1"
                     /translation="CMQALEFPWTF"
     J_segment       258..295
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>298
                     /gene="IGKC"
BASE COUNT           73 a           68 c           87 g           70 t
ORIGIN      
        1 acatgggcgg cctccatctc ctgcaggtct agtcagagcc tcttggatag tgaggatgga
       61 aacacctatt tggaatggta cctacagagg ccaggccagt ctccacagct cttaatttat
      121 gaggtttcct accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact
      181 gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta ttactgcatg
      241 caagctctag agtttccgtg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003874             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24527:13940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003874
VERSION     KCVT01003874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24527:13940"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81399.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aggccaggcc
      241 agtctgtaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003875             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9426:12574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003875
VERSION     KCVT01003875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9426:12574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81400.1"
                     /translation="CLQYKSFPYTF"
     J_segment       389..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c           99 g           98 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg tgggagacac tgtcaccatc acttgccgga caagtcaagg
      181 tattaccaat tatttacatt ggtttcagca gaaaccaggg agagccccta agctcctgat
      241 ctatgaaaca tccagtttga caagtggggt cccatcaagg ttcagcggca gtgcatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tctacagtat aaaagtttcc cgtacacctt tggccagggg accaaactgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003876             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22546:3974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003876
VERSION     KCVT01003876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22546:3974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81401.1"
                     /translation="CQQHDNSPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          118 c          111 g           88 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctctc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggtg
      181 ttagcgactg gttggcctgg tatcaacaga gaccagggaa agcccctaaa ctcctgatct
      241 atagggcgtc caatttggat acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgctaca tattactgtc
      361 aacagcatga taattcccct ccgacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003877             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:21479:14174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003877
VERSION     KCVT01003877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21479:14174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81402.1"
                     /translation="CQQYNNLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          111 c          103 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcaattat ttaaattggt atcaacagaa accggggaaa gcccctaaac tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca acctgaggat tttgcaactt attcctgtca
      361 acagtataat aatttaccgt ggacgttcgg ccaagggacc aaggtggata tcaaacgag
//
LOCUS       KCVT01003878             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13982:12318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003878
VERSION     KCVT01003878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13982:12318"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81403.1"
                     /translation="CLQYRSYPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          110 c          104 g           96 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 tagcagttat ttaaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataga agttacccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01003879             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24891:3801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003879
VERSION     KCVT01003879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24891:3801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..389
                     /note="immunoglobulin light chain variable region"
     V_region        56..389
     V_segment       56..352
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81404.1"
                     /translation="CMQALEFPLTF"
     J_segment       353..389
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>392
                     /gene="IGKC"
BASE COUNT           83 a          100 c          116 g           93 t
ORIGIN      
        1 acatgggctc ctgggactgc taatgctctg gctccctgga tccagcgggg acgtagtgat
       61 gacccagact ccactctccc tgtccgtcac ccttggagag tcggcctcca tctcctgcag
      121 gtctagtcag agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca
      181 gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt
      241 cccagacagg ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt
      301 ggaggctggg gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt
      361 cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003880             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18433:4992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003880
VERSION     KCVT01003880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18433:4992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..348
                     /note="immunoglobulin light chain variable region"
     V_region        27..348
     V_segment       27..311
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81405.1"
                     /translation="CQQNSNWPLTF"
     J_segment       312..348
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           85 a          101 c           94 g           71 t
ORIGIN      
        1 acatggggct cccagatacc accggagaaa tagtgatgac gcagtctcca gccaccctgt
       61 ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt gtcagcagca
      121 gcttagcctg gtaccaacaa aaacctgggc aggctcccag gctcctcatc tatggtgcat
      181 ccagcagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg acagacttca
      241 ctctcaccat caccagcctg gagcctgaag atgttgcagt ctatttttgt cagcagaata
      301 gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003881             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13029:7565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003881
VERSION     KCVT01003881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13029:7565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81406.1"
                     /translation="CQQYNSLPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          110 c          112 g           99 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattg agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcagggcgtt aacgtttatt taaattggta tcaacagaaa ccggggaaag cccctaagcc
      241 cctgatcttt tatgcaaacc gtttggaacg tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaagtta
      361 ttattgtcaa cagtataata gtttaccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01003882             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16259:19792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003882
VERSION     KCVT01003882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16259:19792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81407.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          116 c          109 g           88 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagga
      181 tattaacaac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aggtcctgat
      241 ctatagggca tccattttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003883             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:9599:15945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003883
VERSION     KCVT01003883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9599:15945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81408.1"
                     /translation="CMQSLEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctggccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcta gagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaatc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01003884             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:15339:4164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003884
VERSION     KCVT01003884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15339:4164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81409.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgccctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003885             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19912:19703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003885
VERSION     KCVT01003885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19912:19703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81410.1"
                     /translation="CQQHDNSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          118 c          104 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat aattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003886             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6999:7576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003886
VERSION     KCVT01003886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6999:7576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..414
                     /note="immunoglobulin light chain variable region"
     V_region        94..414
     V_segment       94..362
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81411.1"
                     /translation="CLQGDSAPLTF"
     J_segment       377..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          102 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctccttctgc tctggctccc aggtgccaga agtgacatcc agatgaccca gtctccatct
      121 tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 aacgattatt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg cctgatctat
      241 gctgcatcca gtttacaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tattgtctac
      361 agggtgattc tgccccgctc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01003887             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14434:16470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003887
VERSION     KCVT01003887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14434:16470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..299
                     /note="immunoglobulin light chain variable region"
     V_region        8..299
     V_segment       8..261
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81412.1"
                     /translation="CQQYNSLPYIF"
     J_segment       262..299
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>302
                     /gene="IGKC"
BASE COUNT           85 a           69 c           73 g           75 t
ORIGIN      
        1 acatgggctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
       61 cattagcgtt tttttaaatt ggtatcagca gaaaccgggg aaagccccta aacccctgat
      121 ctattatgca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      181 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      241 tcaacagtat aatagtttac cgtacatttt tggccagggg accaaagtgg agatcaaacg
      301 ag
//
LOCUS       KCVT01003888             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22159:5739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003888
VERSION     KCVT01003888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22159:5739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81413.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          125 c          112 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt acatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003889             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10052:10034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003889
VERSION     KCVT01003889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10052:10034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81414.1"
                     /translation="CLHYNSDPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          108 c          105 g          100 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatctgtaa gagacagagt caccttcact tgcagggcaa gtcagggcat
      181 tacaactttt ttaaattggt gtcagcagaa atcaggaaaa actcctaagc gcctgatctg
      241 tgttgaatac agtttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 aggtttcact ctcaccatca gcagcctgca gcctgaagat tttacaactt attcctgtct
      361 tcattataac agtgacccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003890             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24858:6721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003890
VERSION     KCVT01003890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24858:6721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81415.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtggg gatcaaacga g
//
LOCUS       KCVT01003891             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:25528:12583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003891
VERSION     KCVT01003891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25528:12583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81416.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggagtttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003892             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21061:5416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003892
VERSION     KCVT01003892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21061:5416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81417.1"
                     /translation="CQQYNNLPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          112 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg cccccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taataattta cctctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003893             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11308:5010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003893
VERSION     KCVT01003893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11308:5010"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81418.1"
                     /translation="CQQYDSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          114 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggc gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003894             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7358:10497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003894
VERSION     KCVT01003894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7358:10497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81419.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          121 c          123 g          103 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccctgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga agatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctggagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01003895             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15273:8473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003895
VERSION     KCVT01003895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15273:8473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81420.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttagcgagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca actcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003896             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22212:3972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003896
VERSION     KCVT01003896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22212:3972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81421.1"
                     /translation="CQQGYSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          118 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gcaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattggcaa tactttaaat tggtatcaac agaaaccggg gaaagcccct acactcctga
      241 tctatagggc atccggtttg caaagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttat ccgtacagtt ttggtcaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01003897             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:22567:11840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003897
VERSION     KCVT01003897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22567:11840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81422.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccct ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003898             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13943:2250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003898
VERSION     KCVT01003898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13943:2250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81423.1"
                     /translation="CQQYNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          118 c          107 g           93 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca actgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataataatt attctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003899             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19892:13244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003899
VERSION     KCVT01003899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19892:13244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81424.1"
                     /translation="CQQYDSDPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcttggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctatttcg catccacttt ggaaagtggc gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003900             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:20568:18150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003900
VERSION     KCVT01003900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20568:18150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..457
                     /note="immunoglobulin light chain variable region"
     V_region        143..457
     V_segment       143..420
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <403..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81425.1"
                     /translation="CQQDYNYSF"
     J_segment       425..457
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>460
                     /gene="IGKC"
BASE COUNT          107 a          120 c          126 g          107 t
ORIGIN      
        1 acatggggct gccctgaaga cttttttgta gcctggtcac accctgtgca ggagtcagtc
       61 tcagacagga cacagcatgg acatgagggt ccccgtgcag ctcctggggc tcctgttgct
      121 ctggctccaa ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
      181 atctgtagga gacagaatca cagtcacttg ccgggcgagt caaggcatta agaaggagtt
      241 aggtggtatc agtagaaacc agggaaagtc ccaacactcc tggtctctgc tgcctccact
      301 ttgcagacgg gggtctcatc tcggttcagt ggctgtggat ctgggacaga tttcactcac
      361 accgtcagca gcctgcagcc tgaagatgtt gcaactaatt actgtcaaca ggattataat
      421 tactctttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003901             544 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11690:20224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003901
VERSION     KCVT01003901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 544)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11690:20224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    220..541
                     /note="immunoglobulin light chain variable region"
     V_region        220..541
     V_segment       220..499
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <481..>513
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81426.1"
                     /translation="CQQYDSDSLTF"
     J_segment       504..541
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        542..>544
                     /gene="IGKC"
BASE COUNT          136 a          138 c          134 g          136 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtaagg aagggaacat tagaagttta cctaagccag
      121 tgagctcagt actgcctgcc ttttcaggga agttctctta ctacatgatt aattatctgg
      181 acatttgttt ttatgtttcc aatctcaggt gccaaatgtg acatccagat gacccagtct
      241 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      301 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      361 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      421 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      481 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      541 cgag
//
LOCUS       KCVT01003902             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6439:7583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003902
VERSION     KCVT01003902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6439:7583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81427.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          118 c          122 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca cccttagaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaggccagg
      241 ccagtctcca cagctcttaa tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003903             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14401:8132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003903
VERSION     KCVT01003903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14401:8132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81428.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacactt atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01003904             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14343:14705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003904
VERSION     KCVT01003904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14343:14705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81429.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003905             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21939:20425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003905
VERSION     KCVT01003905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21939:20425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..366
                     /note="immunoglobulin light chain variable region"
     V_region        89..366
     V_segment       89..328
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81430.1"
                     /translation="CQQYDSDPFTF"
     J_segment       331..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           93 a           97 c          101 g           78 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gagacagagt caccatcact tgtcgggcga
      121 gtcagggcgt tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc
      181 ccttgatcta ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      301 attactgtca acagtatgac agtgacccgt tcactttcgg tggagggacc aagatagaga
      361 tcaaacgag
//
LOCUS       KCVT01003906             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:27329:14380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003906
VERSION     KCVT01003906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:27329:14380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81431.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          118 c          103 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gcccagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01003907             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14361:4381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003907
VERSION     KCVT01003907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14361:4381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81432.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          117 c          120 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc atacgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gtagagtgga ggctgaggat
      361 gttgggattt attactgcat gcaagctcta gagtttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01003908             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:25470:14105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003908
VERSION     KCVT01003908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25470:14105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..247
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81433.1"
                     /translation="CQQGYNTPWTF"
     J_segment       248..285
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           79 a           72 c           77 g           60 t
ORIGIN      
        1 acatgggagg agacaaagtc accatcactt gccgagtcag tcagggtatt agcaggtggt
       61 tagcctggta tcagcagaaa ccagggaaag cccctagact cctgatctat aaggcgtcca
      121 ctttggcaag tggggtccca tcaaccttca gcggcagtgg atctgggacg gattacactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttattgtcaa cagggttaca
      241 ataccccgtg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003909             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14641:2425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003909
VERSION     KCVT01003909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14641:2425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81434.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          117 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcccggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003910             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:21980:11298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003910
VERSION     KCVT01003910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21980:11298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81435.1"
                     /translation="CYQHSRGWAF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           97 a          122 c          116 g           83 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaaa ttatattgac acagtctcca
      121 gccaccctgt ctttggcacc aggggaaaga gccactctct cctgcagggc cagtgagaat
      181 gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag gctcctcgtc
      241 cacagtgcgt ccagcagggc cactgacatc ccagacaggt tcagtggcag tgggtctcgg
      301 acagagttca ccctcaccat cagcagtctg gagcctgaag atgttggagt ctattactgc
      361 tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01003911             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15001:17544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003911
VERSION     KCVT01003911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15001:17544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81436.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          107 c          107 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003912             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:6556:6356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003912
VERSION     KCVT01003912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6556:6356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81437.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggtacagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003913             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15531:21938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003913
VERSION     KCVT01003913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15531:21938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81438.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          122 c          110 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacgact cgtgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata aatttcacac tggaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01003914             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:27741:12349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003914
VERSION     KCVT01003914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:27741:12349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81439.1"
                     /translation="CMQSLEIPPTF"
     J_segment       409..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          108 t
ORIGIN      
        1 acatggggtg attgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg gggatggaaa cacctatttg gattggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca atctctagag attcctccca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01003915             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:25480:16302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003915
VERSION     KCVT01003915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25480:16302"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81440.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          121 c          108 g           90 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacagccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccacgg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003916             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:26781:10446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003916
VERSION     KCVT01003916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:26781:10446"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81441.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgctaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003917             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19707:10187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003917
VERSION     KCVT01003917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19707:10187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..384
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81442.1"
                     /translation="CQHGYGIQLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          116 c          114 g           96 t
ORIGIN      
        1 acatgggggg gagtcagtcc cagtcaggac acagcatgga catgagggcc cccactcagc
       61 tcctggggtt cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgca tctgtgggag acagagtcac catctcttgc caggcgagtc
      181 aggacattag caatgattta gcctggtatc agcagaaacc gggaaaagcc cctaggctcc
      241 tgatgtataa ggcatccgct ttgcagattg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcaaca gcctgcagcc tgaagatttt gcaacttact
      361 actgtcaaca tggttatggt atccagctca ctttcggtgg agggaccaag gtggacatca
      421 aacgag
//
LOCUS       KCVT01003918             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14557:3912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003918
VERSION     KCVT01003918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14557:3912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81443.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003919             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:15105:16575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003919
VERSION     KCVT01003919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15105:16575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..403
                     /note="immunoglobulin light chain variable region"
     V_region        82..403
     V_segment       82..365
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81444.1"
                     /translation="CQQYNSLPYSF"
     J_segment       366..403
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT          100 a          104 c          105 g           97 t
ORIGIN      
        1 acatggggac acagcatgga catgagggtc cccgctcagc tcctggggct cctgctgctc
       61 tggctcccag gtgccagatg tgacattgag atgacccagt ctccatcctc cctgtctgct
      121 tctgtaggag acagagtcac catcacttgc cgggcaagtc agggcgttaa cgtttattta
      181 aattggtatc agcagaaacc ggggaaagcc cctaagcccc tgatctttta tgcaaaccgt
      241 ttggaacgtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga attcactctc
      301 accatcagca gcctgcaacc tgaagatttt gcaagttatt attgtcaaca gtataatagt
      361 ttaccgtaca gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01003920             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15979:5140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003920
VERSION     KCVT01003920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15979:5140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81445.1"
                     /translation="CQQVYSNPAF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          101 a          111 c          108 g           97 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccaggtgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataggaa tttagcgtgg tatcagcaga gaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc cagattgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcaacctac agcctgaaga ttctgcaatt tattactgtc
      361 aacaggttta tagtaacccg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01003921             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18947:9726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003921
VERSION     KCVT01003921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18947:9726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81446.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagac
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01003922             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14458:15310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003922
VERSION     KCVT01003922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14458:15310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81447.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gttggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003923             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9069:5287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003923
VERSION     KCVT01003923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9069:5287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81448.1"
                     /translation="CQQGYNTPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          116 c          119 g           91 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcg tccctgtctg catctgtagg agacaaagtc accatcactt gccgagccag
      181 tcaggatatt agcagctggt tagcctggta tcagctgaag ccggggaaag cccctaaact
      241 cttgatctat aaggcgtcca gtttggcaag aggggtccca tcgaggttca gcggcagtgg
      301 atctgggacg gattacactc tcaccatcag cagcctgcag cctgaagatt ttgcatctta
      361 ttattgtcaa cagggttaca ataccccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01003924             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:27502:11276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003924
VERSION     KCVT01003924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:27502:11276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    168..290
                     /note="immunoglobulin light chain variable region"
     V_region        168..290
     V_segment       168..250
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <227..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81449.1"
                     /translation="CQQHNSYPPWTF"
     J_segment       253..290
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>293
                     /gene="IGKC"
BASE COUNT           71 a           90 c           67 g           65 t
ORIGIN      
        1 acatgggaat cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cacatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg tgggagacac agtcaccatc tcttgtcgga cagatttcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tatcactgtc aacaacataa
      241 tagttaccct ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01003925             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14295:19074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003925
VERSION     KCVT01003925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14295:19074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81450.1"
                     /translation="CIQGLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgacgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atacaaggtc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003926             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13394:5901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003926
VERSION     KCVT01003926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13394:5901"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81451.1"
                     /translation="CLQTKNSPWTF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca atggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcat ctgcagagcc agtgagagtg
      181 tcagtgtctt tggaataaac ctcattcact ggtatcagca gaaaccagga caacctccta
      241 aacccctgat ttaccaagca tccaataaag aaactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaagctgac gatgctgcag
      361 attattactg tctgcagact aagaattctc cgtggacgtt tggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01003927             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14460:13329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003927
VERSION     KCVT01003927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14460:13329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81452.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatt acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01003928             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16139:13616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003928
VERSION     KCVT01003928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16139:13616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81453.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          119 c          125 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01003929             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15264:18022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003929
VERSION     KCVT01003929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15264:18022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81454.1"
                     /translation="CQQHNTYPTTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          119 c          104 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagtctggt atcagcagaa accagggaaa gccccgaagc ccctgatgta
      241 ttacgcatcc aatttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccta ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003930             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12331:3842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003930
VERSION     KCVT01003930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12331:3842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81455.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaaggag
//
LOCUS       KCVT01003931             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10020:14822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003931
VERSION     KCVT01003931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10020:14822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..310
                     /note="immunoglobulin light chain variable region"
     V_region        8..310
     V_segment       8..267
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81456.1"
                     /translation="CQQGYSYPWTF"
     J_segment       273..310
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>313
                     /gene="IGKC"
BASE COUNT           78 a           83 c           80 g           72 t
ORIGIN      
        1 acatgggctc cctcctccct gtccgcatct gtgggagacg cagtcacgat cacttgccag
       61 gcgagtcaag gcattggcaa taacttaaat tggtttcagc agaaaccagg gaaagcccct
      121 aaactcctga tctataagac atccagtttg caaagtggga ttccctctcg gttcagcggc
      181 agtggatctg ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc
      241 acttattact gtcaacaggg ttatagttac ccgtggacgt tcggccaagg ggccaaggtg
      301 gagatcaaac gag
//
LOCUS       KCVT01003932             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15171:11491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003932
VERSION     KCVT01003932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15171:11491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81457.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          113 c          112 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgga acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003933             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21594:6400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003933
VERSION     KCVT01003933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21594:6400"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81458.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggttcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003934             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:8668:9936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003934
VERSION     KCVT01003934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8668:9936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81459.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          123 c          115 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcccttgat ccagtgggga cattgtgatg acccagaatc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01003935             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19205:5220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003935
VERSION     KCVT01003935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19205:5220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81460.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagcttg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct gggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggc acctgcagag gccaggccag
      241 tctccacagc tcttgattta tgaagtttcc tatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagttccctt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003936             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:27598:9068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003936
VERSION     KCVT01003936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:27598:9068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81461.1"
                     /translation="CLQFKTFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          117 c          107 g          103 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atctcttgtc gggcaagtca
      181 gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc ctaagctcct
      241 catctatgct gcatccactt tggccggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagac ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tttaaaactt tcccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01003937             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12942:11613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003937
VERSION     KCVT01003937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12942:11613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81462.1"
                     /translation="CLQGYIDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          113 c          111 g           99 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtcggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg gcttattact
      361 gtctacaggg ttatattgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01003938             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22758:7725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003938
VERSION     KCVT01003938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22758:7725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81463.1"
                     /translation="CQHSFDTPYTF"
     J_segment       389..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          119 c          110 g           96 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg cctctgctca
       61 gctcctaggg ctcctgctgc tctggctccc aggcgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagggcaag
      181 tgcgaacgtt aacaactatt tacattggta tcagcagaaa ccagggaaag tccctgagct
      241 cctgatctat gctgcatcgt ctttgcaaag tggggtccca tcaaggttca gcggcagtgg
      301 gtctgggaca gatttcaccc tcaccatcag cagcctgcag cctgaagatg ttgcaactta
      361 ttactgtcag cacagttttg atacccccta cacttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01003939             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13394:20270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003939
VERSION     KCVT01003939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13394:20270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81464.1"
                     /translation="CLQGYIDPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          113 c          112 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtcggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattga cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003940             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14049:9941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003940
VERSION     KCVT01003940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14049:9941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..374
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81465.1"
                     /translation="SMHDYGWPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          112 c          118 g           92 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtctccatct cctgccaagc cagagcagat
      181 gtacatggtg aaatatcttg gatccggata aaccttgaac aaagacttga accccattta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagaccggt tcatcagcaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 atgcatgact atgggtggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01003941             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18825:22714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003941
VERSION     KCVT01003941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18825:22714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81466.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          111 g          111 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aagctccctg ctcagctcct
       61 ggggctgcta atgctctggc tctctggttc cagtggggat gttgtgatga cccagactcc
      121 attctccctg tccgttagcc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttgaat agtgaagacg gaaacaccta tttggattgg tacctgcaga ggccgggcca
      241 gtctccacag cccttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttgggatt tatatctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01003942             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10780:16515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003942
VERSION     KCVT01003942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10780:16515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81467.1"
                     /translation="CQQYNTDPPTF"
     J_segment       387..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          126 c          103 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcccccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagca gtcatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattaca catccatttt ggaaagtggg gtcccatcaa ggttccgcgg cagtggatct
      301 gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacactga ccctcccact ttcggccccg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003943             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17789:15756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003943
VERSION     KCVT01003943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17789:15756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..289
                     /note="immunoglobulin light chain variable region"
     V_region        15..289
     V_segment       15..251
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81468.1"
                     /translation="CQQYDSDPFTF"
     J_segment       254..289
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>292
                     /gene="IGKC"
BASE COUNT           75 a           72 c           80 g           65 t
ORIGIN      
        1 acatgggggg agtcagaccc agtctccatc acttgtcggg cgagtcaggg cattcgcagt
       61 tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat ctattacgcg
      121 tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc
      181 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagtat
      241 gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg ag
//
LOCUS       KCVT01003944             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16720:18489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003944
VERSION     KCVT01003944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16720:18489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..422
                     /note="immunoglobulin light chain variable region"
     V_region        103..422
     V_segment       103..387
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81469.1"
                     /translation="CQQHNSYPRTF"
     J_segment       389..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>427
                     /gene="IGKC"
BASE COUNT          106 a          117 c          112 g           92 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtaccagat gtgacatcca gatgacccag
      121 tctccatctt ccttgtctgc atctgtagga gacagagtca ccatcacttg ccaagccagt
      181 cagggtattg gcaactggtt agcctggtat cggcagaaac cagggaaagc ccctaagctc
      241 ctgatctatg ctgcatccag tttacaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcagc agcataatag ttatcctcgg acgttcggcc aagggaccaa ggtggaaatc
      421 aagcgag
//
LOCUS       KCVT01003945             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18537:5617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003945
VERSION     KCVT01003945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18537:5617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..388
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81470.1"
                     /translation="CQKYISSPFTF"
     J_segment       389..426
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           98 a          132 c          106 g           93 t
ORIGIN      
        1 acatggggga gctgctcagt taggacccag agagaaccat ggaaatccca gctcagcttc
       61 tcttcctcct gctactgtgg ctcccagtct caggtaccac cggacaactt atattgactc
      121 agtctccagc caccctgtct ctgtctccag gggaaagagc caccctctcc tgcagggcca
      181 gtcagagtgt tggcagcagc ttagcctggt accagcagaa acctgggcag gcccccaggc
      241 tcctcctcta tggtgcatcc agcagggcca ctggcatccc agacaggttc agtggcagtg
      301 ggtctgggac agagttcact ctcaccatca gcagcctgga gcctgaagat tttgcagtat
      361 attactgtca gaaatatatt agctccccat tcactttcgg ccccgggacc aaactggata
      421 tcaaacgag
//
LOCUS       KCVT01003946             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5829:9077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003946
VERSION     KCVT01003946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5829:9077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81471.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaccgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggaaatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct ctagagtttc cttggacgtt cggccagggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003947             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:5319:8742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003947
VERSION     KCVT01003947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:5319:8742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81472.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          103 a          111 c          104 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtat gcatctgtag gagacactgt caccatcact tgccgggcaa gtcatggttt
      181 tagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tccttatctc
      241 tgctgcatcc agtttggaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaagcgag
//
LOCUS       KCVT01003948             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16007:8168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003948
VERSION     KCVT01003948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16007:8168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..364
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81473.1"
                     /translation="CQQGYYTPFTF"
     J_segment       379..414
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT           96 a          119 c          107 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatctct tgccgagcca gtcagggtat
      181 tagcagctgg ttagcctggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taaggcgtcc agtttggcaa gtggggtccc atcaaggttc agcggcagtg gatttgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgctactt atttttgtca
      361 acagggttac tataccccat tcactttcgg ccccgggacc aaactggata tcaatcgag
//
LOCUS       KCVT01003949             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8665:7781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003949
VERSION     KCVT01003949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8665:7781"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81474.1"
                     /translation="CQQYDSDPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagtc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgctca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01003950             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:4950:13380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003950
VERSION     KCVT01003950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:4950:13380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..439
                     /note="immunoglobulin light chain variable region"
     V_region        101..439
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81475.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          116 g          108 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 accacagtgg agattaaacg ag
//
LOCUS       KCVT01003951             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19134:6231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003951
VERSION     KCVT01003951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19134:6231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81476.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003952             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21853:15581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003952
VERSION     KCVT01003952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21853:15581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81477.1"
                     /translation="CQQNDNWARTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          120 c          118 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag acaccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagaggcac cctctcctgt agggccagtc
      181 agagtgtcag cagcagttta gcctggtacc agcagaaacc tggacaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatgataac tgggctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01003953             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14559:18823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003953
VERSION     KCVT01003953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14559:18823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81478.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          124 c          112 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg tatcccagac aggttcagtg tcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003954             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13914:7924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003954
VERSION     KCVT01003954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13914:7924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81479.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          115 c          108 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc tgtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcaggatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc attttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003955             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18247:4850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003955
VERSION     KCVT01003955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18247:4850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81480.1"
                     /translation="CIQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtct cagacaggtt
      301 cagtggcagt gggtctgaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca ttcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01003956             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12859:3760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003956
VERSION     KCVT01003956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12859:3760"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81481.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003957             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:4715:13785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003957
VERSION     KCVT01003957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4715:13785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81482.1"
                     /translation="CMQALEFPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           96 a          117 c          119 g          105 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccat acgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagt agagtggagg ctgaggatgt
      361 tgggatttat tactgcatgc aagctctaga gtttcctctc actttcggcg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01003958             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24339:10604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003958
VERSION     KCVT01003958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24339:10604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81483.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          117 c          126 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tgtcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003959             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19967:7440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003959
VERSION     KCVT01003959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19967:7440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81484.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcat ccttggagag ccggcctcca tatcctgcac gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattattg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003960             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24287:13930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003960
VERSION     KCVT01003960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24287:13930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81485.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003961             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19116:8420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003961
VERSION     KCVT01003961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19116:8420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81486.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          118 c          104 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg aatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01003962             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:21559:3553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003962
VERSION     KCVT01003962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21559:3553"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81487.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcgggggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003963             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20346:8381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003963
VERSION     KCVT01003963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20346:8381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81488.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctcccggtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003964             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17797:18059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003964
VERSION     KCVT01003964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17797:18059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81489.1"
                     /translation="CQQYNSLPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          112 c          112 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggggacag agtcaccatc acttgccggg caagtcagga
      181 cattagtagt tttttaaatt ggtatcagca gaaaccgggg aaagcccctc agctcctgat
      241 ctactatgca aaccgtttgg agagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcga cttatcactg
      361 tcaacagtat aatagtttac cgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003965             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12163:17856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003965
VERSION     KCVT01003965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12163:17856"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81490.1"
                     /translation="CMQGLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          118 c          126 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccgctctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgag gttggagaca cctatttgga gtggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tgtccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag gtctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01003966             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19023:17679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003966
VERSION     KCVT01003966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19023:17679"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81491.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          118 c          108 g           86 t
ORIGIN      
        1 acatgggggg cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagccacga
      181 tataaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcagca tcagcagcct gcagcctgaa gatttcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01003967             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14825:8192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003967
VERSION     KCVT01003967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14825:8192"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81492.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttttgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accagggtgg aaatcaaacg ag
//
LOCUS       KCVT01003968             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16118:17466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003968
VERSION     KCVT01003968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16118:17466"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81493.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatgtggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagcc cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003969             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21097:18498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003969
VERSION     KCVT01003969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21097:18498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81494.1"
                     /translation="CQQYSSLVAF"
     J_segment       385..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          107 c          113 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccggatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccca aaggtcctga
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tacaacctga ggattttgca acttattact
      361 gtcaacagta tagtagttta gtcgctttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01003970             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:3661:13352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003970
VERSION     KCVT01003970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3661:13352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81495.1"
                     /translation="CLQYKTYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          105 a          113 c          103 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa acttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01003971             562 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20883:13978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003971
VERSION     KCVT01003971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 562)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20883:13978"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    238..559
                     /note="immunoglobulin light chain variable region"
     V_region        238..559
     V_segment       238..521
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <499..>531
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81496.1"
                     /translation="CQQHDNAPWTF"
     J_segment       522..559
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        560..>562
                     /gene="IGKC"
BASE COUNT          136 a          164 c          147 g          115 t
ORIGIN      
        1 acatgggggc ccctgtgctg agttactgag atgagccagc cctgcagctg tgcccagcca
       61 gccccatccc ctgatgattt gcatgttccc agagcacagc cccctgccct gaagacttat
      121 taatagactg gtcacaccct gtgcaggagt cagtctcaga caggacacag catggacacg
      181 agggtccccg ctcagctcct ggggctcctg ttgctctggc tcccaggtgc cagatgtgac
      241 atccagatga cccagtctcc atcctccctg tctgcatctg taggagacag agtcaccatc
      301 acttgcagag ccagtcagag tattaacgac tggttggcct ggtatcaaca gagaccaggg
      361 aaggccccta agctcctgat ctatagggca tccaatttgg aaacaggggt cccatcaagg
      421 ttcagtggaa gtggatctgg gacagatttc actctcagca tcagcagcct gcagcctgaa
      481 gatatcgcaa catattactg tcagcagcat gacaatgccc cgtggacgtt cggccaaggg
      541 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01003972             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18846:10151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003972
VERSION     KCVT01003972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18846:10151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81497.1"
                     /translation="CMQGLEFPITF"
     J_segment       404..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          124 c          119 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgatgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cgctgatttc acactgacaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc caatcacttt cggccccggg
      421 tccaaactgg agatcaaacg ag
//
LOCUS       KCVT01003973             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10374:13708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003973
VERSION     KCVT01003973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10374:13708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81498.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcaacagaa accagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003974             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5728:7272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003974
VERSION     KCVT01003974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5728:7272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81499.1"
                     /translation="CQQGYSYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccctc
      121 ctccctgtcc gcatctgtgg gagacgcagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataac ttaaattggt ttcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttacccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01003975             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20354:4306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003975
VERSION     KCVT01003975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20354:4306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81500.1"
                     /translation="CQQGDSYPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          112 c          114 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgtcccagtc
      121 tccttcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaga gattatttaa attggtatca gcagcaaccg gggaaagccc ctaaactcct
      241 gatgtattat gcaaacagtc tggcaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcagtctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag ggtgacagtt atcctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01003976             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12667:3488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003976
VERSION     KCVT01003976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12667:3488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81501.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           94 t
ORIGIN      
        1 atgggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01003977             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10306:10633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003977
VERSION     KCVT01003977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10306:10633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81502.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aagattcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacctatt
      361 actgtcaaca gtatgacagt gatccgttca ctttcggtgg ggggaccaag gtagacatca
      421 aacgag
//
LOCUS       KCVT01003978             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:28443:13757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003978
VERSION     KCVT01003978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:28443:13757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81503.1"
                     /translation="CLQYKSFPYTF"
     J_segment       390..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c           99 g           98 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtattaccaa ttatttacat tggtttcagc agaaaccagg gagagcccct aagctcctga
      241 tctatgaaac atccagtttg acaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagtttc ccgtacacct ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01003979             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:22762:5181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003979
VERSION     KCVT01003979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22762:5181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81504.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          102 a          118 c          114 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccaccagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 tcgag
//
LOCUS       KCVT01003980             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19999:9938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003980
VERSION     KCVT01003980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19999:9938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81505.1"
                     /translation="CQQVYSNPAF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          112 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccaggtg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag gaatttagcg tggtatcagc agagaccagg gaaagcccct aagctcctca
      241 tctatgctgc atccaggttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcaacc tacagcctga agattctgca atttattact
      361 gtcaacaggt ttatagtaac ccggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01003981             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14328:20174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003981
VERSION     KCVT01003981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14328:20174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..329
                     /note="immunoglobulin light chain variable region"
     V_region        8..329
     V_segment       8..287
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81506.1"
                     /translation="CQQYDSDSLTF"
     J_segment       292..329
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>332
                     /gene="IGKC"
BASE COUNT           85 a           86 c           85 g           76 t
ORIGIN      
        1 acatggggac atccagatga cccagtctcc atcctccctg tctgcatctg taggagacag
       61 agtcaccatc acttgtcggg cgactcagga cattcgcagt tatttagcgt ggtatcagca
      121 gaaaccaggg aaagccccga agcccttgat ctattacgcg tccactttgg aaagtggggt
      181 cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct
      241 gcagcctgaa gattttgcaa cttattactg tcaacagtat gacagtgatt cgctcacttt
      301 cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003982             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24219:10910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003982
VERSION     KCVT01003982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24219:10910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81507.1"
                     /translation="CQQHDNSPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          119 c          113 g           89 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctctctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gggtgttagc gactggttgg cctggtatca acagagacca gggaaagccc ctaaactcct
      241 gatctatagg gcgtccaatt tggatacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg ctacatatta
      361 ctgtcaacag catgataatt cccctccgac gttcggccaa gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01003983             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18984:8290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003983
VERSION     KCVT01003983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18984:8290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81508.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01003984             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17496:4253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003984
VERSION     KCVT01003984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17496:4253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81509.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacagtctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003985             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:9488:15331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003985
VERSION     KCVT01003985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9488:15331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81510.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          127 c          121 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01003986             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24811:9406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003986
VERSION     KCVT01003986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24811:9406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..378
                     /note="immunoglobulin light chain variable region"
     V_region        57..378
     V_segment       57..341
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81511.1"
                     /translation="CQQNSNWPLTF"
     J_segment       342..378
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>381
                     /gene="IGKC"
BASE COUNT           91 a          113 c           97 g           80 t
ORIGIN      
        1 acatgggagc acagcttctc ttcctcctgc tgctctggct cccagatacc accggagaaa
       61 tagtgatgac gcagtctcca gccaccctgt ctttgtctcc aggagaaaga gccaccctct
      121 cctgcagggc cagtcagagt gtcagcaaca gcttagcctg gtaccaacaa aaacctgggc
      181 agcctcccag gctcctcatc tatggtgcat ccagcagggc cactggcatc ccagacaggt
      241 tcagaggcag tgggtctggg acagacttca ctctcaccat caccagcctg gagcctgaag
      301 atgttgcagt ttattattgt cagcagaata gtaactggcc tctcactttc ggtggaggga
      361 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003987             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15169:14774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003987
VERSION     KCVT01003987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15169:14774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81512.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgtgat gacccagact
      121 ccactctccc tggccgtcac tcttggagag ccgacctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 atcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01003988             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12867:22784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003988
VERSION     KCVT01003988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12867:22784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81513.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          116 g          111 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggatatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcatggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01003989             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17310:9680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003989
VERSION     KCVT01003989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17310:9680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81514.1"
                     /translation="CQQYDSFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c           97 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgttg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaactggt atcagcagaa accgggaaaa gcccccaaac tcctgatcta
      241 ttatacaaat cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acaatatgat agttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01003990             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24959:18288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003990
VERSION     KCVT01003990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24959:18288"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81515.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          117 c          104 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctacagcct gaggattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01003991             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:21694:14868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003991
VERSION     KCVT01003991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21694:14868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..417
                     /note="immunoglobulin light chain variable region"
     V_region        100..417
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81516.1"
                     /translation="CQQGYSYHPTF"
     J_segment       387..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>424
                     /gene="IGKC"
BASE COUNT           94 a          120 c          110 g          100 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acttccttat gacgcagtct
      121 ccttcctccc tgtccgcatc tgtaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 gccattggca ctaatttaaa ttggtatcag cagagaccag gaaaagcccc taaactcctg
      241 atctataggg cttccggttt gcagagtggg actccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcagtctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta ccatcccact ttcggcggag ggaccaaggt ggagatccaa
      421 cgag
//
LOCUS       KCVT01003992             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14175:9548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003992
VERSION     KCVT01003992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14175:9548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81517.1"
                     /translation="CIQPLDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattgctgc attcaacctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01003993             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18204:19316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003993
VERSION     KCVT01003993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18204:19316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..395
                     /note="immunoglobulin light chain variable region"
     V_region        74..395
     V_segment       74..357
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81518.1"
                     /translation="CQQYNSDPYTF"
     J_segment       358..395
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>398
                     /gene="IGKC"
BASE COUNT           97 a          105 c          104 g           92 t
ORIGIN      
        1 acatgggatg gacatgaggg tccccgctca gctcctagga ctcctgctgc tctgtctccc
       61 aggtgccaaa tgtgacatcc aggtgaccca gtctccatcc tccctgtctg catctgtagg
      121 agacagagtc accatcactt gtcgggcgag tcagggcatt agaagttatt tagcgtggta
      181 tcagctgaga ccagggaaag ccccgaaggc cttaatctat tacgcgacca ttttggaaag
      241 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      301 cagcctgcag cctgaggatt ttgcaactta tttctgtcaa cagtataaca gtgacccgta
      361 cacttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01003994             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18826:21150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003994
VERSION     KCVT01003994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18826:21150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81519.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ctatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01003995             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12568:19117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003995
VERSION     KCVT01003995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12568:19117"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..300
                     /note="immunoglobulin light chain variable region"
     V_region        8..300
     V_segment       8..266
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <244..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81520.1"
                     /translation="CMQYTHMPLTF"
     J_segment       267..300
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>307
                     /gene="IGKC"
BASE COUNT           76 a           73 c           88 g           70 t
ORIGIN      
        1 acatgggctg gacagccggc ctccatctcc tgcaggtcta gtcagagcct cttggacagt
       61 gaagatggaa acacctattt ggattggtac ctacaaaagc cgggccagtc gccacagccc
      121 ttgatttatg aggtttccaa tcgggcctct ggagtccctg acaggttcag tggtagtggg
      181 tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt tgggatttat
      241 tactgcatgc aatatacaca catgccgctc actttcggcg gagggaccaa ggtggagatc
      301 gaacgag
//
LOCUS       KCVT01003996             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24516:7875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003996
VERSION     KCVT01003996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24516:7875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81521.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaaatg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01003997             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:29000:14240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003997
VERSION     KCVT01003997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:29000:14240"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81522.1"
                     /translation="CQKYSSPPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          122 c          116 g           89 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtatcaccg gacaagttat cttgactcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagaatgttg gcagcaggtt agcctggtac caacagaaac ctgggcaggc ccccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcaccccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccgtcagt agcctggagc ctgaagattt tgcagtgtat
      361 tactgtcaga agtatagtag tcccccgtgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01003998             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14879:16796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003998
VERSION     KCVT01003998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14879:16796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81523.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          117 c           97 g           96 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacactggt ttcagcagaa accagggaga gcccctaaac tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01003999             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9476:16156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01003999
VERSION     KCVT01003999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9476:16156"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81524.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004000             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22392:7116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004000
VERSION     KCVT01004000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22392:7116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81525.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt tttttactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaagttgga aatcaaacga g
//
LOCUS       KCVT01004001             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12878:19665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004001
VERSION     KCVT01004001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12878:19665"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..314
                     /note="immunoglobulin light chain variable region"
     V_region        7..314
     V_segment       7..277
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81526.1"
                     /translation="CQQDFDWPPTF"
     J_segment       280..314
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>317
                     /gene="IGKC"
BASE COUNT           72 a           95 c           84 g           66 t
ORIGIN      
        1 acatgggcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
       61 cagggccagt cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc
      121 tcccaagctc ctcctctatg gtgcatccac cagggcctcc ggcatcccag gcaggttcag
      181 tgccagtggg tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt
      241 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      301 ggtggaaatc aaacgag
//
LOCUS       KCVT01004002             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14858:3454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004002
VERSION     KCVT01004002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14858:3454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81527.1"
                     /translation="CQQYNTLPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          117 c          105 g           97 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gagattcaga tgacccagtc
      121 tccatcctcc ctgtctgcct ctgtcggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc aattatttaa attggtatca gcagagaccg gggaaagccc ctaaactcct
      241 gatctattat gcatcccgtt tggagaatgg ggtcccatca aagttcagcg gcagtggatc
      301 tgggacagaa ttcagtctca ccatcagtag cctgcaacct gaagattttg cagcttatta
      361 ctgtcagcag tataatacct taccattcac tttcggcccc gggaccaaac tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004003             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9935:19403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004003
VERSION     KCVT01004003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9935:19403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..327
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81528.1"
                     /translation="CQQYNSDPFTF"
     J_segment       328..365
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           95 a          100 c           87 g           86 t
ORIGIN      
        1 acatggggga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagta accatcactt gtcgggcgag
      121 tcaggacata agaagttatt tagcgtggta tcagcagaaa ccaggcaaag ccccgaagcc
      181 cttgatctat tacgcatccg ttttggaaag tggggtccca tcaaggttca gtggcagtgg
      241 atctgggaca gaattcactc tcaccatcac cagtctgcag cctgaggatt ttgcaactta
      301 ttactgtcaa cagtataaca gtgacccatt cactttcggc cccgggacca aactggatac
      361 caaacgag
//
LOCUS       KCVT01004004             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:12666:4354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004004
VERSION     KCVT01004004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12666:4354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81529.1"
                     /translation="CQQYDSDSLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          117 c          111 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      181 tcaggacatt cgcagttatt tagcgtggta tcaacagaaa ccagggaaag ccccgaggcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01004005             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:27937:9460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004005
VERSION     KCVT01004005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:27937:9460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81530.1"
                     /translation="CLQGYSAPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          119 c          106 g           96 t
ORIGIN      
        1 acatggggca gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cttccctgtc tgcttcggta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcgatta tttaagttgg tatcagcaga aaccaggaaa aactcctcag cgcctgatct
      241 atgctgcgtc cagtttggaa ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcagtc tattactgtc
      361 tacagggtta tagtgcccca ttcactttcg gccccgggac caaactcgat atcaaacgag
//
LOCUS       KCVT01004006             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:12738:15870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004006
VERSION     KCVT01004006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12738:15870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81531.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcagacgag
//
LOCUS       KCVT01004007             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20503:8457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004007
VERSION     KCVT01004007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20503:8457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81532.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004008             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24154:12089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004008
VERSION     KCVT01004008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24154:12089"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..413
                     /note="immunoglobulin light chain variable region"
     V_region        99..413
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81533.1"
                     /translation="CQQYNTLPLTF"
     J_segment       383..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cactcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct gagctcctga
      241 tctattatgc aaaccgtttg gaaactgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttattact
      361 gtcaacagta taatacttta ccgctcactt tcggcggagg gaccaaggtg gaggtcagac
      421 gag
//
LOCUS       KCVT01004009             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:7261:4310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004009
VERSION     KCVT01004009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:7261:4310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81534.1"
                     /translation="CQQYDSDPRTF"
     J_segment       377..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           99 a          113 c          112 g           90 t
ORIGIN      
        1 atgggatcaa cgcagagtac atgggggaca tgagggtccc cgctcagctc ctaggactcc
       61 tgctgctctg tctcccaggc gccaaatgtg acatccagat gacccagtct ccatcctccc
      121 tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca
      181 gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg
      241 cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagagt
      301 tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt
      361 atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01004010             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18368:4370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004010
VERSION     KCVT01004010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18368:4370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81535.1"
                     /translation="CLQSKNSPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgtcttt ggaataaacc tcattcactg gtatcagcag aaaccaggac accctcctaa
      241 acccctgatt taccaagcat ccaatagaga cactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgacg atgctgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggacgttt ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01004011             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:8639:11710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004011
VERSION     KCVT01004011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8639:11710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81536.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cattgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004012             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12067:13912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004012
VERSION     KCVT01004012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12067:13912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81537.1"
                     /translation="CMQGTQLPYSF"
     J_segment       275..312
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           70 a           77 c           93 g           75 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tggggctact ggtgctctgg ctccctggga ccagtggaga tattgtgatg acccagactc
      121 cacagctctt gatctatttg ggttccaaac gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc aggcactgat ttcacactga aaatcagtcg ggtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa ggtacacagc ttccgtacag ttttggccag gggaccaaag
      301 tggagatcaa acgag
//
LOCUS       KCVT01004013             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18092:9103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004013
VERSION     KCVT01004013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18092:9103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81538.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          120 c          108 g           89 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacc aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacaa cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004014             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15289:10627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004014
VERSION     KCVT01004014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15289:10627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..335
                     /note="immunoglobulin light chain variable region"
     V_region        14..335
     V_segment       14..295
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <275..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81539.1"
                     /translation="CLQESNWSYSF"
     J_segment       298..335
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>338
                     /gene="IGKC"
BASE COUNT           80 a           93 c           98 g           67 t
ORIGIN      
        1 acatgggacc ggagaaatag tggtgacaca gtctccagcc accctgtctt tgtctccagg
       61 ggaaagagcc accctctcct gcagggccag tcagagtgtc aaaagcaggt tagcctggta
      121 ccagcagaaa cctgggcaag ctcccaggct cctcatgtat gatgcgtcca gcagggccac
      181 tggcatccca gacaggttca ctggcagcgg gtctgggcca gagttcactc tcaccatcag
      241 cagcctggag cccgaagatg ttgcggttta tttctgtctt caggagagta actggtcgta
      301 cagctttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01004015             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25814:12784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004015
VERSION     KCVT01004015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25814:12784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81540.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccaggcaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004016             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:8205:18136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004016
VERSION     KCVT01004016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8205:18136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81541.1"
                     /translation="CQQYNSLPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          109 c          111 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgca tctctggggg acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cagatattta aattggtatc agcagaaacc ggggaaagcc cctaagttcc
      241 tgatctatta tgtaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 attgtcaaca gtataatagt ttaccgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004017             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11676:8982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004017
VERSION     KCVT01004017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11676:8982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81542.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          126 c          117 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggcggagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01004018             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20327:13557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004018
VERSION     KCVT01004018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20327:13557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81543.1"
                     /translation="CQQYFSSPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           94 a          128 c          109 g           93 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagctc cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01004019             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18533:17313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004019
VERSION     KCVT01004019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18533:17313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81544.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt ttctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagccaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004020             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15610:20696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004020
VERSION     KCVT01004020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15610:20696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..363
                     /note="immunoglobulin light chain variable region"
     V_region        45..363
     V_segment       45..328
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81545.1"
                     /translation="CQQHNSYPLTF"
     J_segment       330..363
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>369
                     /gene="IGKC"
BASE COUNT           92 a          103 c           92 g           82 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc
       61 agtctccatc ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa
      121 gtcagggcat taccaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc
      181 ccctgatcta ttacgcatcc aatttggaaa ctggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      301 attactgtca acagcataat agttacccac tcactttcgg cggagggacc aaggtggaga
      361 tcagacgag
//
LOCUS       KCVT01004021             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15126:10811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004021
VERSION     KCVT01004021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15126:10811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81546.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          111 g          111 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aagctccctg ctcagctcct
       61 ggggctgcta atgctctggc tctctggttc cagtggggat gttgtgatga cccagactcc
      121 attctccctg tccgttagcc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttgaat agtgaagacg gaaacaccta tttggattgg tacctgcaga ggccgggcca
      241 gtctccacag cccttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttgggatt tatatctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01004022             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9365:3078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004022
VERSION     KCVT01004022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9365:3078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81547.1"
                     /translation="CQHSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          107 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacgcagtct
      121 ccaccctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgcg
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagtccc tgagctcctg
      241 atctatgcta catcgtcttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcaccctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcata gttatgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004023             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12488:12412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004023
VERSION     KCVT01004023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12488:12412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81548.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcatctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01004024             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:20855:17368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004024
VERSION     KCVT01004024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20855:17368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81549.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          113 c           99 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagctt ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccagttat ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgaaacatcc actttggtaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcatctt attactgtct
      361 acagtataaa agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004025             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15664:17462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004025
VERSION     KCVT01004025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15664:17462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81550.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          126 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggccacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01004026             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23153:14304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004026
VERSION     KCVT01004026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23153:14304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81551.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          114 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcag ctgagaccag ggaaagcccc gaaggcctta
      241 atctattacg cgaccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg acgattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004027             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23783:17374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004027
VERSION     KCVT01004027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23783:17374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81552.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004028             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11844:4104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004028
VERSION     KCVT01004028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11844:4104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..358
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81553.1"
                     /translation="SMHDYGWPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           98 a          115 c          116 g           92 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtgtccatct cctgccaagc cagaccagat
      181 gtacatggtg aaataccttg gatccggata aaccttgaac aaagacttga acccctttta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagcccggt tcatcaccaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 atgcatgact atgggtggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 a
//
LOCUS       KCVT01004029             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:26499:13049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004029
VERSION     KCVT01004029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26499:13049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81554.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004030             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:9048:14839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004030
VERSION     KCVT01004030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9048:14839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81555.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          105 a          124 c          120 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagtgt agcctggtac cagcaaaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01004031             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14608:12985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004031
VERSION     KCVT01004031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14608:12985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..318
                     /note="immunoglobulin light chain variable region"
     V_region        8..318
     V_segment       8..276
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81556.1"
                     /translation="CQQYDSDSLTF"
     J_segment       281..318
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           82 a           83 c           83 g           73 t
ORIGIN      
        1 acatggggac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
       61 cttgtcgggc gagtcagggc attcgcagtt atttagcgtg gtatcagcag aaaccaggga
      121 aagccccgaa gcccttgatc tattacgcgt ccactttgga aagtggggtc ccatcaagat
      181 tcagcggcag tggatctggg acagaattca ctctcaccat cagcagcctg cagcctgaag
      241 attttgcaac ttattactgt caacagtatg acagtgactc gctcactttc ggtggaggga
      301 ccaaggtaga gatcaaacga g
//
LOCUS       KCVT01004032             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15239:17670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004032
VERSION     KCVT01004032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15239:17670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81557.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgtg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatcttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004033             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14216:8620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004033
VERSION     KCVT01004033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14216:8620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81558.1"
                     /translation="CLQYKSFPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          111 a          116 c           96 g           97 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccatcac ttgccggaca agtcaaggta
      181 ttaccaatta tttacattgg tttcaacaga aaccagggaa agcccctaaa ctcctgatct
      241 atgaaacatc cagtttgaca agtggggtcc catcaaggtt cagcggcagc gcatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtataa aagtttcccg tacacttttg gccaggggac caaactggag atcaaacgag
//
LOCUS       KCVT01004034             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21154:17002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004034
VERSION     KCVT01004034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21154:17002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81559.1"
                     /translation="CQHSYDTPYTF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          116 c          105 g           96 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgcgaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agtccctgag ctcctgatct
      241 atgctgcatc gtctttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac cctcaccatc agtagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtta tgataccccc tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004035             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16712:5003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004035
VERSION     KCVT01004035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16712:5003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81560.1"
                     /translation="CQQGNGLPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          110 c          109 g          101 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcagttgc cgggcaagtc
      181 aggccattag cagttattta tattggtatc agcagaaacc ggggaaagcc cctaaacttc
      241 tgatttataa ggcaaatctt ttggaagatg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc actatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtcaaca gggtaatggt ttaccattca ctttcggccc cgggaccaaa gtggatatca
      421 aacgag
//
LOCUS       KCVT01004036             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6470:16722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004036
VERSION     KCVT01004036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6470:16722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81561.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttgggatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004037             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23851:4952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004037
VERSION     KCVT01004037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23851:4952"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81562.1"
                     /translation="CMQALEFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctca tgctctggct ccctgtatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagt
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcggtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgatgat
      361 gttggggttt attactgcat gcaagctcta gagtttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004038             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6782:5345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004038
VERSION     KCVT01004038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6782:5345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81563.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct ctcagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004039             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12277:20773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004039
VERSION     KCVT01004039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12277:20773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..442
                     /note="immunoglobulin light chain variable region"
     V_region        123..442
     V_segment       123..402
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81564.1"
                     /translation="CQQYDSDTRTF"
     J_segment       410..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>447
                     /gene="IGKC"
BASE COUNT          108 a          122 c          121 g           96 t
ORIGIN      
        1 acatggggga ggctaggcac gcttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca ggtgccaaat
      121 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      181 ccatcacttg tcgggcgagt cagggcattc gcagttattt agcgtggtat cagcagaaac
      241 cagggaaagc cccgaagccc ttgatctatt acgcgtccac tttggaaagt ggggtcccat
      301 caaggttcag cggcagtgga tctgggacag aattcactct caccatcagc agcctgcagc
      361 ctgaagattt tgcaacttat tactgtcaac agtatgacag tgacacgcgc actttcggtg
      421 gagggaccaa ggtggagatc aatcgag
//
LOCUS       KCVT01004040             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4071:19071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004040
VERSION     KCVT01004040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4071:19071"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81565.1"
                     /translation="CQQDYSWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g           88 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tgtcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcatcttag cctggtacca ccagaaacct gggcaggctc ccaagtccct
      241 catctatggt gcaaccagta gggccaccgg catcccagac aggttcagtg gcattgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gcgtttatta
      361 ctgtcagcag gattatagct ggccactcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004041             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:6554:15470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004041
VERSION     KCVT01004041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6554:15470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..273
                     /note="immunoglobulin light chain variable region"
     V_region        1..273
     V_segment       1..236
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <213..>245
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81566.1"
                     /translation="CQQHDDSPRTF"
     J_segment       238..273
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        274..>276
                     /gene="IGKC"
BASE COUNT           82 a           70 c           68 g           56 t
ORIGIN      
        1 acatgggcac catcacttgc agagccagtc aggatattaa cacctggttg gcctggtatc
       61 aacagaagcc agggaaagcc cctaaggtcc tgatctatag gacatccaat ttggaaacag
      121 gggtcccatc aaggttcagt ggaagtggat ctgggacaga tttcactctc accatcaaca
      181 gcctgcagcc tgaagatatc gcaacatatt actgtcaaca gcatgatgat tcccctcgga
      241 cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004042             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13214:11892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004042
VERSION     KCVT01004042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13214:11892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81567.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004043             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5393:8669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004043
VERSION     KCVT01004043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5393:8669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81568.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          100 a          120 c          118 g          105 t
ORIGIN      
        1 acatggggat gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccattggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggttcctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004044             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14578:13158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004044
VERSION     KCVT01004044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14578:13158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81569.1"
                     /translation="CQQHNTYPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagtaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aaacccctga
      241 tcttttacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taatacttac ccgtacactt ttggccaggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004045             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13033:12840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004045
VERSION     KCVT01004045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13033:12840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81570.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          117 c          107 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacgtc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgcacagcca gtcacgatat
      181 taataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004046             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11342:14431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004046
VERSION     KCVT01004046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11342:14431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81571.1"
                     /translation="CQQGYTYLYSF"
     J_segment       384..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          115 c          107 g          101 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgttggaga cacagtcacc atcacttgcc aggcgagtca
      181 agccattgcc aataatttaa attggtatca gcagaaacca ggaaaagccc ctaaagtcct
      241 gatctatagg gcatccagtt tgcaaagtgg gtttccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcagcag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatactt acttgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004047             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13650:14936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004047
VERSION     KCVT01004047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13650:14936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81572.1"
                     /translation="CQQGKSNPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          112 c          111 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 atcctccctg tctgcatccg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagtgat tctttaaatt ggtatcaaca gaaaccgggg aaagccccta agctcctgat
      241 cttttatgca aacagtttgg caagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagtagcct gcagcctgaa gattttgcga cttattactg
      361 tcaacagggt aaaagtaatc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004048             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8791:15151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004048
VERSION     KCVT01004048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8791:15151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81573.1"
                     /translation="CLQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc ttgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004049             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:27151:9175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004049
VERSION     KCVT01004049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:27151:9175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81574.1"
                     /translation="CQQYDNDPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          117 c          109 g           92 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc aacagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca atatgacaat gacccgctca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01004050             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14126:10604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004050
VERSION     KCVT01004050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14126:10604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81575.1"
                     /translation="CLQFKTFPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          117 c          105 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga tatccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct aagctcctca
      241 tctatgctgc atccactttg gccggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagactt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagtt taaaactttc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004051             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24825:4784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004051
VERSION     KCVT01004051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24825:4784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81576.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          116 c          105 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggtcg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004052             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10428:9153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004052
VERSION     KCVT01004052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10428:9153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81577.1"
                     /translation="CQQHADSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          118 c          112 g           89 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggtattagca actggttggc ctggtatcaa cagagaccag ggaaagcccc taaggtcctg
      241 atttatagga catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aaccggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc tacatattac
      361 tgtcaacagc atgctgattc ccctcggacg ttcggccaag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004053             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14902:4582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004053
VERSION     KCVT01004053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14902:4582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81578.1"
                     /translation="CMQALDFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttttgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactaatttc acactgaaaa tcagcagtgt ggaggctgag
      361 gatgttgggg tctattactg catgcaagct ctagactttc cttacagttt tggccagggg
      421 accacagtgg agattaaacg ag
//
LOCUS       KCVT01004054             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22805:10695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004054
VERSION     KCVT01004054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22805:10695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81579.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tttagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc cccgacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004055             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11781:9713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004055
VERSION     KCVT01004055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11781:9713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81580.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctac agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004056             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10668:11737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004056
VERSION     KCVT01004056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10668:11737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..414
                     /note="immunoglobulin light chain variable region"
     V_region        101..414
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81581.1"
                     /translation="CLQGDSTPFTF"
     J_segment       391..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>425
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g           95 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaaccg ggaaaagctc ctaagcgcct
      241 aatctatgct gcatccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtctacag ggtgatagta ccccgttcac ttttggccag gggaccaaag tggacgtcaa
      421 acgag
//
LOCUS       KCVT01004057             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19987:12585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004057
VERSION     KCVT01004057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19987:12585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81582.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccagtttgg aaagtggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttactactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01004058             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16100:7454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004058
VERSION     KCVT01004058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16100:7454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81583.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004059             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19680:17985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004059
VERSION     KCVT01004059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19680:17985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81584.1"
                     /translation="CQQHDNMPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          114 c          116 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtgggag acagagtcac catcacttgc agggccagtc
      181 agggtattag caactggttg gcctggtatc aacagaaacc agggaaagcc cctaagctcc
      241 tgatctatag ggcatggaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ccgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgataat atgccgctca ctttcggtgg agggaccaag gtggacatca
      421 aacgag
//
LOCUS       KCVT01004060             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14469:11436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004060
VERSION     KCVT01004060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14469:11436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81585.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          104 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgattta
      241 tagggcatcc agtttgcaaa gtgggtttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004061             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5171:17515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004061
VERSION     KCVT01004061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5171:17515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81586.1"
                     /translation="CMQSLEIPPSF"
     J_segment       407..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acgcagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccacccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattactgc atgcaatctc tagagattcc tcccagtttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004062             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12306:16655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004062
VERSION     KCVT01004062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12306:16655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81587.1"
                     /translation="CIQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggat tggtacctgc agaggccggg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag ccccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcattcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004063             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:6484:4815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004063
VERSION     KCVT01004063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6484:4815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81588.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           99 a          116 c          117 g          100 t
ORIGIN      
        1 acatgggggt gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga caacctccta
      241 aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac gatggtgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01004064             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23237:19811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004064
VERSION     KCVT01004064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23237:19811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    179..290
                     /note="immunoglobulin light chain variable region"
     V_region        179..290
     V_segment       179..253
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <230..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81589.1"
                     /translation="CQQHNGYPPTF"
     J_segment       256..290
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>293
                     /gene="IGKC"
BASE COUNT           70 a           94 c           72 g           57 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccat gcctgcgaag tcacccatca gggcctgagc tcgcccgtca ccaagagctt
      181 cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt gtcaacagca
      241 taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac gag
//
LOCUS       KCVT01004065             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21971:18366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004065
VERSION     KCVT01004065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21971:18366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81590.1"
                     /translation="CQQYTSFPLTF"
     J_segment       387..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcact atcacttgcc gggcaagtga
      181 ggacgttagc agtcatttaa attggtatca acagaaaccg gggaaagccc ctaagctcct
      241 gatctatttt gcaaaccgtt tggaaagtgg ggtcccatca aggatcagcg gcagtggatc
      301 tgggacagaa ttcagtctca ccatcagcag cctgcaagct gaggactttg caacttatca
      361 ctgtcaacag tacactagtt tccccctcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01004066             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19679:3950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004066
VERSION     KCVT01004066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19679:3950"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..464
                     /note="immunoglobulin light chain variable region"
     V_region        143..464
     V_segment       143..426
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>436
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81591.1"
                     /translation="CQQYDSDPFTF"
     J_segment       429..464
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        465..>467
                     /gene="IGKC"
BASE COUNT          114 a          128 c          121 g          104 t
ORIGIN      
        1 acatggggct gccctgaaga cttattaata ggctaggcac gcttcatgca ggagtcagac
       61 ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctaggac tcctgctgct
      121 ctgtctccca ggtgccaaat gtgacatcca gatgacccag tctccatcct ccctgtctgc
      181 atctgtagga gacagagtca ccatcacttg tcgggcgagt cagggcattc gcagttattt
      241 ggcgtggtat caccagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac
      301 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      361 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      421 tgacccgttc actttcggtg gagggaccaa ggtagagatc aaacgag
//
LOCUS       KCVT01004067             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16000:18880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004067
VERSION     KCVT01004067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16000:18880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..270
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81592.1"
                     /translation="CQQRNTYPYMCSF"
     J_segment       280..314
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>317
                     /gene="IGKC"
BASE COUNT           83 a           79 c           81 g           74 t
ORIGIN      
        1 acatgggcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc
       61 aagtcaggac attagcagtt atttagcctg gtatcagcag aaaccaggga aagcccctag
      121 gctcctgatc tataaggcgt ccagtttgca aagtggggtc ccatcaaggt tcagcggcag
      181 tggatctggg acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcagt
      241 ttattactgt caacagcgta atacttaccc gtacatgtgc agttttggcc aggggaccaa
      301 agtggagatc aaacgag
//
LOCUS       KCVT01004068             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20934:6431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004068
VERSION     KCVT01004068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20934:6431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81593.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          119 c          117 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac tctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcgtttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga cttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004069             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25813:13763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004069
VERSION     KCVT01004069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25813:13763"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81594.1"
                     /translation="CMQVTQLLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          117 c          113 g           97 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca accggcctcc atctcctgca ggtctagtca aagccttcta
      181 cacactgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg agactgagga tgttggagtt
      361 tattactgca tgcaagttac acagcttctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01004070             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13331:2945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004070
VERSION     KCVT01004070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13331:2945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81595.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004071             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14641:6768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004071
VERSION     KCVT01004071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14641:6768"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81596.1"
                     /translation="CQQYDSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          114 c          112 g           95 t
ORIGIN      
        1 acatgggagg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004072             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22748:12940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004072
VERSION     KCVT01004072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22748:12940"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81597.1"
                     /translation="CQQNSNWPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          122 c          114 g           84 t
ORIGIN      
        1 acaggggact gctcagttag gacccagagg gaaccatgga agccccagca cagcttctct
       61 tcctcctgct gctctggctc ccagatacca ccggagaaat agtgatgacg cagtctccag
      121 gcaccctgtc tttgtctcca ggagaaagag ccaccctctc ctgcagggcc agtcagagtg
      181 tcagcagcag cgtagcctgg taccagcaga aacctgggca ggctcccaga ctcctcatct
      241 atggtgcatc caacagggcc actggcatcc cagacaggtt cagtggcagt gggtctggga
      301 cagagttcac tctcaccatc agcagcctgg agcctgaaga tgttgcactt tattattgtc
      361 agcagaatag taactggcct ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004073             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12964:13363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004073
VERSION     KCVT01004073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12964:13363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..406
                     /note="immunoglobulin light chain variable region"
     V_region        85..406
     V_segment       85..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81598.1"
                     /translation="CQQHNTYPYTF"
     J_segment       369..406
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>409
                     /gene="IGKC"
BASE COUNT          101 a          113 c          104 g           91 t
ORIGIN      
        1 acatggggag gacacagcat ggacatgagg gtccccgctc agctcctggg gctcctgctg
       61 ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc ctccctgtct
      121 gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat tagtaatgat
      181 ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt ttacgcatcc
      241 aatttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac agatttcact
      301 ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca acagcataat
      361 acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004074             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20413:13509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004074
VERSION     KCVT01004074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20413:13509"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81599.1"
                     /translation="CIQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atacaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004075             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13414:18004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004075
VERSION     KCVT01004075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13414:18004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81600.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatctaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004076             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24413:11161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004076
VERSION     KCVT01004076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24413:11161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81601.1"
                     /translation="CQQDYSWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          120 c          119 g           87 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttgtcttcc tcctgctact ctggatccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcatctt agcctggtac caccagaaac ctgggcaggc tcccaagtcc
      241 ctcatctatg gtgcaaccag tagggccacc ggcatcccag acaggttcag tggcagtggg
      301 tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt tggcgtttat
      361 tactgtcagc aggattatag ctggccactc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01004077             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:5867:13236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004077
VERSION     KCVT01004077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:5867:13236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81602.1"
                     /translation="CLQGDSTPFTF"
     J_segment       389..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          101 a          115 c          112 g           95 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gggtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccggg aaaagctcct aagcgcctaa
      241 tctatgctgc atccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg tgatagtacc ccgttcactt ttggccaggg gaccaaagtg gacgtcaaac
      421 gag
//
LOCUS       KCVT01004078             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20229:8833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004078
VERSION     KCVT01004078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20229:8833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    31..352
                     /note="immunoglobulin light chain variable region"
     V_region        31..352
     V_segment       31..314
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <292..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81603.1"
                     /translation="CLQGYSPPFTF"
     J_segment       315..352
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>355
                     /gene="IGKC"
BASE COUNT           90 a           94 c           85 g           86 t
ORIGIN      
        1 acatggggtc caatctcagg tgccagatgt gacatccaga tgacccagtc tccatcttcc
       61 ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca ggacattagc
      121 gattatttaa gttggtatca gcagaaacca ggaaaaactc ctgagcgcct gatctatgct
      181 gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa
      241 ttcactctca ccatcagcag cctgcagcct gaagattttg cacgttattt ctgtctacag
      301 ggttatagtc ccccattcac tttcggcccc gggaccaaac tggatttcaa acgag
//
LOCUS       KCVT01004079             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24471:16762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004079
VERSION     KCVT01004079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24471:16762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81604.1"
                     /translation="CQQGHDYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          106 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc caaatgacgc agtctccatc
      121 ctccctgtcc acatctgtag gagacacagt cacgatcact tgccggtcga gtctaggcat
      181 tggcaaattt ttaaattggt atcagcaaaa accagggaaa gcccccaaac tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gtagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcat gattacccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004080             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17958:3057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004080
VERSION     KCVT01004080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17958:3057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81605.1"
                     /translation="CQQGYSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          118 c          106 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgcag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcaatact ttaaatttgt atcaacagaa accggggaaa gcccctacac tcctgatcta
      241 tagggcatcc ggtttgcaaa gtgggactcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttatccgt acagttttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01004081             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8785:13557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004081
VERSION     KCVT01004081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8785:13557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..400
                     /note="immunoglobulin light chain variable region"
     V_region        82..400
     V_segment       82..362
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81606.1"
                     /translation="CQQHDNSPWTF"
     J_segment       363..400
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>403
                     /gene="IGKC"
BASE COUNT          102 a          112 c          105 g           84 t
ORIGIN      
        1 acatggggac acagcatgga cacgagggtc cccgctcagc tcctggggct cctgttgctc
       61 tggctcccag gtgccagatg tgacatccag atgacccagt ctccatcctc cctgtctgca
      121 tctgtaggag acagagtcac catcacttgc agagccagtc agagtattaa cgactggttg
      181 gcctggtatc aacagagacc agggaaggcc cctaagctcc tgatctatag ggcatccaat
      241 ttggaaacag gggtcccatc aaggttcagt ggaagtggat ctgggacaga tttcactctc
      301 accatcagca gcctgcagcc tgatatcgca acatattact gtcaacagca tgataattcc
      361 ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004082             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20931:17332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004082
VERSION     KCVT01004082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20931:17332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81607.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004083             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22130:8131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004083
VERSION     KCVT01004083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22130:8131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..254
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81608.1"
                     /translation="CQQHDNSPRTF"
     J_segment       256..291
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>294
                     /gene="IGKC"
BASE COUNT           87 a           75 c           72 g           60 t
ORIGIN      
        1 acatgggatc tgtaggagac agagtcacca tcacttgcac agccagccac gatataaata
       61 tctggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg atctataggg
      121 catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct gggacagatt
      181 tcaccctcac catcagcagc ctgcagcctg aagatttcgc aacatattac tgtcaacagc
      241 atgataattc ccctcggacg ttcggccaag ggaccaaggt ggaagtcaaa cgag
//
LOCUS       KCVT01004084             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16505:4971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004084
VERSION     KCVT01004084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16505:4971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81609.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01004085             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7250:17387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004085
VERSION     KCVT01004085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7250:17387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..404
                     /note="immunoglobulin light chain variable region"
     V_region        102..404
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81610.1"
                     /translation="CQKYSSSPFTF"
     J_segment       386..404
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           87 a          120 c          107 g           90 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttatt ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccagactcc
      241 tcgtctatgg tgcatccagg agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagaa gtatagtagt tccccattca ctttcggccc cggg
//
LOCUS       KCVT01004086             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22060:10142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004086
VERSION     KCVT01004086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22060:10142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81611.1"
                     /translation="CQQYFSSPFTF"
     J_segment       385..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT           95 a          128 c          111 g           91 t
ORIGIN      
        1 acatggggga gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacg ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagagctggt agcagcttag cctggtacca gcagaaacct gggcaggccc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcaccctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagcag tattttagct ccccattcac tttcggcccc gggaccaaac tggatatcag
      421 acgag
//
LOCUS       KCVT01004087             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21103:9687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004087
VERSION     KCVT01004087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21103:9687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..351
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81612.1"
                     /translation="CQQYNSDSLTF"
     J_segment       356..393
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           94 a          103 c          107 g           92 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag
       61 gtgccaaatg tgacatccag atgacccagt ctccatcctc cctgtctgca tcggcaggag
      121 acagagtcac cattaattgt cgggcgagtc aggacattag tagttattta gcgtggtatc
      181 ggcagaggcc agggaaagcc ccggagccct tgatctatta cgcatccgtt ttggaaagtg
      241 gggtcccatc aagattcagc ggcagtggat ctgggacaga tttcactctc accatcagca
      301 gcctgcagcc tgaagatttt ggaacttatt actgtcaaca gtataacagt gactcgctca
      361 ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01004088             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13188:10043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004088
VERSION     KCVT01004088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13188:10043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81613.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagtcttcct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggc
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004089             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14910:14098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004089
VERSION     KCVT01004089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14910:14098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81614.1"
                     /translation="CIQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cattcaagct ctagagtttc cgtggacttt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004090             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15304:15648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004090
VERSION     KCVT01004090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15304:15648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81615.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaagcga g
//
LOCUS       KCVT01004091             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13303:3816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004091
VERSION     KCVT01004091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13303:3816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81616.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          119 c          106 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004092             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8469:9008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004092
VERSION     KCVT01004092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8469:9008"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81617.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct actcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004093             509 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12658:4374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004093
VERSION     KCVT01004093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 509)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12658:4374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..503
                     /note="immunoglobulin light chain variable region"
     V_region        185..503
     V_segment       185..469
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <446..>478
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81618.1"
                     /translation="CQQDYNWPPTF"
     J_segment       472..503
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        504..>509
                     /gene="IGKC"
BASE COUNT          130 a          139 c          133 g          107 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag gtgaggggaa catgaggtgg ttttgcacat
      121 cagtgaaaac tcctgccacc tctgctcagc aagaaatata attaaaattc aatataccac
      181 cggagaagtt gtgatgacgc agtctccggc caccctgtct ttgtctccag gggaaagagc
      241 caccctgtcc tgcagggcca gtcagagtgt tggcagcacc ttaacctggt accaacacaa
      301 acctgggcag gctcccaagc tcctcatcta tggtgcatcc agcagggcca ccggcatccc
      361 agacaggttc agtgccagtg ggtctggaac agagtttact ctcaccatca gcagcctgga
      421 gcctgaagat gttggaattt attactgtca gcaggattat aactggcctc cgacgttcgg
      481 ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01004094             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6643:23487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004094
VERSION     KCVT01004094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6643:23487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81619.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          118 c          106 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagtctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004095             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:15988:7581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004095
VERSION     KCVT01004095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15988:7581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81620.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          125 c          117 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gctgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01004096             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6481:12829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004096
VERSION     KCVT01004096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6481:12829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81621.1"
                     /translation="CMQPLEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ttccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cttatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004097             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13719:20017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004097
VERSION     KCVT01004097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13719:20017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81622.1"
                     /translation="CQQYNSDPYSF"
     J_segment       348..385
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           97 a          100 c          100 g           91 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaat
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcaggacatt aggaattatt tagcgtggta tcagcagaaa
      181 ccagggaaag ccccgaaggc cttgatctat tacacatcca ttttggaaaa tggggtccca
      241 tcaaggttca gcggcggtgg atctgggaca gaattcagtc tcaccatcag cagcctgcag
      301 gctgaggatt ttgcaactta ttactgtcaa cagtataata gtgacccgta cagttttggc
      361 caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01004098             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:23063:17641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004098
VERSION     KCVT01004098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:23063:17641"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81623.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcatc cttggagagc cggcctccat atcctgcacg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004099             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10130:16755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004099
VERSION     KCVT01004099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10130:16755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..366
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81624.1"
                     /translation="SMHDYGWPTTF"
     J_segment       376..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT           99 a          110 c          114 g           90 t
ORIGIN      
        1 acatggggga gcaccgcctg ccagcatgtt cttgggagtt caggtgcagc tcctctggag
       61 cctggctttc tggagggcag tgagtggaga catcatcctg aaccagacgc cagcatccct
      121 gactgcacct ccaggagaga cagtctccat ctcctgccaa gccagagcag atgtacatgg
      181 tgaaatatct tggatccgga taaaccttga acaaagactt gaaccccatt tatctcatgt
      241 cactaccttg gccccaggtg tcgcagaccg gttcatcagc aaggggagtg gcaccagtta
      301 tgttttcagc atcagtgacc tgcagcctgg ggactctggg gactattact ccatgcatga
      361 ctatgggtgg ccaaccactt tcggtggagg gaccaaggtg gagatcaaac gaa
//
LOCUS       KCVT01004100             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19021:8621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004100
VERSION     KCVT01004100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19021:8621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81625.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           92 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gtctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004101             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19286:9215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004101
VERSION     KCVT01004101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19286:9215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81626.1"
                     /translation="CQQSYRYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ttggtatcaa cagaaaccag ggaaagcccc taaactcctg
      241 atatatcttg catccacttt gcagagtggg gtcccatcag ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagatgctgc aacttattac
      361 tgtcagcaga gttatcgtta tccgctcact ttcggtggag ggacccaggt ggaaatcaat
      421 cgag
//
LOCUS       KCVT01004102             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15810:19930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004102
VERSION     KCVT01004102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15810:19930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81627.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tggagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004103             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13033:10860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004103
VERSION     KCVT01004103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13033:10860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..426
                     /note="immunoglobulin light chain variable region"
     V_region        90..426
     V_segment       90..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81628.1"
                     /translation="CGQGTHLPWTF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           99 a          119 c          117 g           94 t
ORIGIN      
        1 acatggggat caggactcct cagttcacca tgaggctccc tgctcagctc ctggggctgc
       61 tattgctctg cgtccccgga tccagtgggg atgttgtgat gactcagtct ccactctccc
      121 tgtccatcac ccctggacag ccggcctcca tctcctgcag gtctagtcaa agccttgtac
      181 acatcaatgg aaacacatac ttgagttggt atcagcagaa cccaggccaa cctccaaggc
      241 gcctaattta tgaggtttct aaccgggact ctggggtccc agacagattc agcggcagtg
      301 gggcagggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttgggcttt
      361 attactgcgg gcaaggtaca caccttccgt ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01004104             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:24068:16896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004104
VERSION     KCVT01004104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24068:16896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..308
                     /note="immunoglobulin light chain variable region"
     V_region        8..308
     V_segment       8..273
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81629.1"
                     /translation="CQQHNSYPRTF"
     J_segment       275..308
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>313
                     /gene="IGKC"
BASE COUNT           81 a           81 c           79 g           72 t
ORIGIN      
        1 acatgggctc catcttcctt gtctgcatct gtaggagaca gagtcaccat cacttgccaa
       61 gccagtcagg gtattggcaa ctggttagcc tggtatcggc agaaaccagg gaaagcccct
      121 aagctcctga tctatgctgc atccagttta caaagtgggg tcccatcaag gttcagcggc
      181 agtggatctg ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca
      241 acttattact gtcagcagca taatagttat cctcggacgt tcggccaagg gaccaaggtg
      301 gaaatcaagc gag
//
LOCUS       KCVT01004105             543 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:9413:15995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004105
VERSION     KCVT01004105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 543)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 543)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..543
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9413:15995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    219..540
                     /note="immunoglobulin light chain variable region"
     V_region        219..540
     V_segment       219..502
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <480..>512
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81630.1"
                     /translation="CQQYNSDPFTF"
     J_segment       503..540
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        541..>543
                     /gene="IGKC"
BASE COUNT          141 a          138 c          127 g          137 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtaagga agggaacatt agaagtttac ctaagccagt
      121 gagctcagta ctgcctgcct tttcagggag gttctcttac tacatgatta attatttgga
      181 catttgtttt tatgtttcca atctcaggtg ccaaatgtga catccagatg acccagtctc
      241 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      301 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      361 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      421 ggacagaatt cactctcacc atcagcagtc tgcagcctga agactttgca acttattact
      481 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      541 gag
//
LOCUS       KCVT01004106             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11001:14315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004106
VERSION     KCVT01004106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11001:14315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..358
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81631.1"
                     /translation="STHDSGGPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           96 a          115 c          119 g           91 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtctccatct cctgccaagc cagagcagat
      181 gtacatggtg aaatgtcttg gatccggata aaccttgaac aaagacttga acccctttta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagcccggt tcatcagcaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 acgcatgact ctggggggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 a
//
LOCUS       KCVT01004107             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18470:5909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004107
VERSION     KCVT01004107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18470:5909"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81632.1"
                     /translation="CQHSYDTPYTF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          119 c          104 g           95 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg acaagtgcga
      181 acgttaacaa ctatttacat tggtatcagc agaaacccgg gaaagcccct gagctcctga
      241 tctatgctgc atccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatgttgca acttattact
      361 gtcagcatag ttatgatacc ccctacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004108             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19136:9765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004108
VERSION     KCVT01004108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19136:9765"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81633.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaaccccct
      241 gatctattac gcatccaatt tgggaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg taacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004109             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11643:17134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004109
VERSION     KCVT01004109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11643:17134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81634.1"
                     /translation="CMQSLEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgctggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctaatttcac actgagaatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004110             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16337:4852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004110
VERSION     KCVT01004110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16337:4852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81635.1"
                     /translation="CQQHDNSPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          116 c          112 g           87 t
ORIGIN      
        1 acatgggggg tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgataattcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004111             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5385:9316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004111
VERSION     KCVT01004111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5385:9316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..445
                     /note="immunoglobulin light chain variable region"
     V_region        106..445
     V_segment       106..408
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <385..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81636.1"
                     /translation="CMQALEFPRTF"
     J_segment       410..445
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT           99 a          122 c          124 g          103 t
ORIGIN      
        1 acatggggac tgactgatca cgactcctca ggtcaccttc tcacaatgag gctccctgct
       61 cagctcctgg gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc
      121 cagactccac ttttcctggc cgtcaccctt ggagagccgg cctccatctc ctgcaggtct
      181 agtcagagcc tcttggctag tgaggatgga aacacttatt tggactggta cctacagggg
      241 ccaggccaga ctccccagct cttgatttat gaggtttcca accgggcctc tggagtccca
      301 gacagggtca gaggcagtgg gtcagacact gagttcacac tgaaaatcag cagagtggag
      361 gctgaggatc ttgggattta ttactgcatg caagctctag agtttcctcg gacgttcggc
      421 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01004112             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16112:9365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004112
VERSION     KCVT01004112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16112:9365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81637.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca cttttggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004113             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15169:8986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004113
VERSION     KCVT01004113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15169:8986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81638.1"
                     /translation="CLQYKSYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          111 c          100 g          101 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatcac ttgccggaca agtcaggata
      181 ttcacattta tttgaattgg tttcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 ctgctgcatc cagtttggaa agtgggttcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctac agcctgaaga ttttgcaact tattattgtc
      361 tacagtataa aagttacccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004114             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18869:16627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004114
VERSION     KCVT01004114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18869:16627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81639.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcatccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004115             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15453:3640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004115
VERSION     KCVT01004115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15453:3640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81640.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc tgcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004116             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19586:16992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004116
VERSION     KCVT01004116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19586:16992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81641.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          110 c          104 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcaattat gtaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaacgttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctcca acctgaagat tttgcaactt attactgtca
      361 acaatataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004117             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21348:16852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004117
VERSION     KCVT01004117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21348:16852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..415
                     /note="immunoglobulin light chain variable region"
     V_region        96..415
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81642.1"
                     /translation="CQQYNSLPYTF"
     J_segment       383..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>420
                     /gene="IGKC"
BASE COUNT          107 a          113 c          103 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttgccaattt tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 attatgcaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc aacagcctac accctgaaga ttttgcaact tattactgtc
      361 aacagtataa tagtttacct tacactttcg gcggagggac caagatggag atcaaccgag
//
LOCUS       KCVT01004118             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19031:8108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004118
VERSION     KCVT01004118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19031:8108"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81643.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac accgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004119             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17264:11200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004119
VERSION     KCVT01004119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17264:11200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81644.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          121 c          117 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctactcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004120             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11483:3602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004120
VERSION     KCVT01004120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11483:3602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81645.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggact ggtacctgca gaagccgggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga ctctgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004121             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11346:2324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004121
VERSION     KCVT01004121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11346:2324"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81646.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctga ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004122             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17203:13876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004122
VERSION     KCVT01004122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17203:13876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81647.1"
                     /translation="CQQSYDTPYTF"
     J_segment       386..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          119 c          107 g           95 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtcc
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagccc ctgagctcct
      241 gatctatgct gcatccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggggcagat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttattt
      361 ctgtcagcaa agttatgata ccccctacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004123             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17227:13996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004123
VERSION     KCVT01004123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17227:13996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81648.1"
                     /translation="CQQYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 gcagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01004124             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24408:17291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004124
VERSION     KCVT01004124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24408:17291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81649.1"
                     /translation="CMQAREFPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004125             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18376:7335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004125
VERSION     KCVT01004125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18376:7335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81650.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacact tacttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004126             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11794:18630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004126
VERSION     KCVT01004126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11794:18630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81651.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          124 c          117 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgataa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cattcacctt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01004127             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23630:11721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004127
VERSION     KCVT01004127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23630:11721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81652.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          119 c          106 g           88 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcggacaa gtcagggcat
      181 taccaatgat ttagcctggt atcagcagag accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01004128             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:21907:6094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004128
VERSION     KCVT01004128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21907:6094"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81653.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccagtttg gaaagtgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01004129             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13233:8341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004129
VERSION     KCVT01004129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13233:8341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81654.1"
                     /translation="CQKYSSFPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          123 c          110 g           94 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaacaccgg acaagttata ttgactcagt
      121 ctccagccac tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggaaggcc cccagactcc
      241 tcatctatgg tgcctccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagaa gtatagtagt ttcccattca ctttcggccc cgggaccaaa ctggatgtca
      421 aacgag
//
LOCUS       KCVT01004130             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:6789:17355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004130
VERSION     KCVT01004130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6789:17355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81655.1"
                     /translation="CQQYNSLPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          109 c          108 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtcccca ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccatg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 catcaactat tatttaaatt ggtatcagca gatgccgggg aaagccccta aggtcctgat
      241 ctattataca aatcgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004131             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:27420:12188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004131
VERSION     KCVT01004131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:27420:12188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81656.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          116 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcttccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004132             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:2787:11631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004132
VERSION     KCVT01004132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:2787:11631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81657.1"
                     /translation="CQQHNSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          111 c          106 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtaccag atgtgacatc cagatgaccc agtctccatc
      121 ttccttgtct gcatctgtag gagacagagt cataatcaat tgccaagcca gtcaggatat
      181 tagcaactgg ttagcctggt atcagcagaa accagggaaa gcccccaagg tcctgatcta
      241 tgatgcatcc agtttgtata gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccataa gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 gcagcataat agttaccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004133             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8491:7885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004133
VERSION     KCVT01004133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8491:7885"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81658.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          124 c          111 g           86 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcttagcctg gtaccaacaa aaacctgggc aggctcccag gctcctcatc
      241 tatggtgcat ccagcagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagacttca ctctcaccat caccagcctg gagcctgaag atgttgcagt ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01004134             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23437:13869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004134
VERSION     KCVT01004134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23437:13869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81659.1"
                     /translation="CLQGYNTPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           95 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccagt tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacctgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gtgtccagtt tggaaggtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagatcttg cgacttatta
      361 ctgtctacag ggttataata ccccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004135             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18773:16079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004135
VERSION     KCVT01004135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18773:16079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81660.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g           93 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctcc gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcagcaga acccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01004136             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15793:17534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004136
VERSION     KCVT01004136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15793:17534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81661.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          126 c          111 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc aacagcttag cctggtacca acaaaaacct gggcagcctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagag gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccacgg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004137             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20484:11797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004137
VERSION     KCVT01004137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20484:11797"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81662.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          119 c          123 g          106 t
ORIGIN      
        1 atggggtgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attctgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc ccgacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004138             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23139:20060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004138
VERSION     KCVT01004138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23139:20060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81663.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          120 c          115 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgagcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004139             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23585:9265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004139
VERSION     KCVT01004139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23585:9265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81664.1"
                     /translation="CQQYNNDPPTF"
     J_segment       387..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          123 c          104 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattggca gtcatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacaatga ccctcccact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01004140             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16213:16794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004140
VERSION     KCVT01004140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16213:16794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81665.1"
                     /translation="CQQYNSLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          108 a          111 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatagttta cctcggacgt tcggccaagg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01004141             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19644:17860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004141
VERSION     KCVT01004141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19644:17860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81666.1"
                     /translation="CQQYDKSPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          119 c          117 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagggtc accatcactt gcagagccag
      181 tcagggtatc agcaactggt tggcctgtta tcaacagaaa ccagggagag cccctaacct
      241 cctgatgtat agggcgtcca atttgcaagg aggggtccca tcaaggttca gaggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaggatg tcgctacata
      361 ttactgtcaa cagtatgata agtcccctcc gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01004142             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14557:9163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004142
VERSION     KCVT01004142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14557:9163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81667.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          119 c          116 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccaggga aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004143             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14284:4878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004143
VERSION     KCVT01004143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14284:4878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81668.1"
                     /translation="CQQYDSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          112 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaactggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004144             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15204:10501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004144
VERSION     KCVT01004144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15204:10501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..267
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <249..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81669.1"
                     /translation="CQQYDSDSLTF"
     J_segment       272..309
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>312
                     /gene="IGKC"
BASE COUNT           79 a           79 c           81 g           73 t
ORIGIN      
        1 acatgggtcc atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg
       61 cgactcagga cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga
      121 agcccttgat ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca
      181 gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa
      241 cttattactg tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg
      301 agatcaaacg ag
//
LOCUS       KCVT01004145             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4891:9017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004145
VERSION     KCVT01004145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4891:9017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81670.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctatggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004146             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7462:19714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004146
VERSION     KCVT01004146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7462:19714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81671.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gtctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004147             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18775:6800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004147
VERSION     KCVT01004147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18775:6800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81672.1"
                     /translation="CQENDNWPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          115 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagtcac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagttta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatca tgcatccacc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagga gaacgataac tggcctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004148             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10465:11389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004148
VERSION     KCVT01004148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10465:11389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81673.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004149             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15866:15554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004149
VERSION     KCVT01004149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15866:15554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81674.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           91 t
ORIGIN      
        1 actggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004150             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11384:19776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004150
VERSION     KCVT01004150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11384:19776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81675.1"
                     /translation="CMQALDFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgcctggc tccctggatc tagtggggac attgtaatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cggtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004151             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18885:4529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004151
VERSION     KCVT01004151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18885:4529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..437
                     /note="immunoglobulin light chain variable region"
     V_region        102..437
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81676.1"
                     /translation="CMQYTHMPLTF"
     J_segment       404..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>444
                     /gene="IGKC"
BASE COUNT           99 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaagctc cctgctcagc
       61 tcctggggct gctaatgctc tggctctctg gatccagtgg ggatattgtg ttgagccaga
      121 ctccactctc cctgtccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggacagtgaa gatggaaaca cctatttgga ttggtacctg caaaagccgg
      241 gccagtcgcc acagcccttg atttatgagg tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaat atacacacat gccgctcact ttcggcggag
      421 ggaccaaggt ggagatcgaa cgag
//
LOCUS       KCVT01004152             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6947:10006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004152
VERSION     KCVT01004152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6947:10006"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81677.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagttcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01004153             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:6256:16346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004153
VERSION     KCVT01004153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:6256:16346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81678.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          114 c          109 g           96 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg actatttaag ttggtatcag cagaaaccag gaaaaactcc taagcgcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggctct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agtttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004154             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17262:5345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004154
VERSION     KCVT01004154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17262:5345"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81679.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gatgctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004155             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15828:13304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004155
VERSION     KCVT01004155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15828:13304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81680.1"
                     /translation="CQQYNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          117 c          105 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataat aattattctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004156             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18913:6163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004156
VERSION     KCVT01004156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18913:6163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81681.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtact gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004157             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12941:17445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004157
VERSION     KCVT01004157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12941:17445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81682.1"
                     /translation="CQQYDSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          115 c          112 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtcg gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa actagggaaa gtcccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004158             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:15790:7068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004158
VERSION     KCVT01004158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15790:7068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81683.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaaac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004159             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14811:20610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004159
VERSION     KCVT01004159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14811:20610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81684.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ctaagcgggc ctctggagtc cccgacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004160             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19671:2569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004160
VERSION     KCVT01004160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19671:2569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81685.1"
                     /translation="CQQHNTYPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagtaa tgatttagcc tggtatcaga agaaaccagg gaaagccccg aagcccctga
      241 tcttttacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcaacc tgcagcctga agattttgca acttattact
      361 gtcaacaaca taatacttac ccgtacactt ttggcccggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004161             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17166:11835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004161
VERSION     KCVT01004161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17166:11835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81686.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactt
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004162             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18371:16397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004162
VERSION     KCVT01004162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18371:16397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81687.1"
                     /translation="CQQYNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taataattat tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004163             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22016:7309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004163
VERSION     KCVT01004163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22016:7309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81688.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga ccctgtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgtaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01004164             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14176:12461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004164
VERSION     KCVT01004164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14176:12461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81689.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          120 c          106 g           92 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc atctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca acataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004165             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15123:12396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004165
VERSION     KCVT01004165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15123:12396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81690.1"
                     /translation="CQQYDGLPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacaaagt caccatcact tgccatgcca gtcagggtat
      181 taggagttgg ttagcctggt atcagcagaa accagggaaa gcccctaagc ccctgatcta
      241 tgctgcatcc actttacaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgat ggtctccctc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004166             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20557:17606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004166
VERSION     KCVT01004166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20557:17606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81691.1"
                     /translation="CQHGYGIQLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          116 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagtcccag tcaggacaca gcatggacat gagggccccc actcagctcc
       61 tggggttcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca gagtcaccat ctcttgccag gcgagtcagg
      181 acattagcaa tgatttagcc tggtatcagc agaaaccggg aaaagcccct aggctcctga
      241 tgtataaggc atccgctttg cagattgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcaacagcc tgcagcctga agattttgca acttactact
      361 gtcaacatgg ttatggtatc cagctcactt tcggtggagg gaccaaggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01004167             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16359:17828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004167
VERSION     KCVT01004167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16359:17828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81692.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaagatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004168             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23007:15323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004168
VERSION     KCVT01004168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23007:15323"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81693.1"
                     /translation="CQQYNSLPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          111 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagca attatttaaa ttggtatcag gagaaaccgg ggaaagcccc taagcccctg
      241 atctattata caaatcgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaagctg aggattttgc aacttattac
      361 tgtcaacagt ataattcttt accgtggacg ttcggccaag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01004169             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:6384:14069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004169
VERSION     KCVT01004169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6384:14069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..322
                     /note="immunoglobulin light chain variable region"
     V_region        123..322
     V_segment       123..284
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81694.1"
                     /translation="CMQALEFPWTF"
     J_segment       285..322
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           72 a           85 c           89 g           79 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctcatgctc tggctccctg tatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      181 aggttcagtg gcggtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      241 gatgatgttg gggtttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa
      301 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01004170             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9222:14673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004170
VERSION     KCVT01004170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9222:14673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..432
                     /note="immunoglobulin light chain variable region"
     V_region        96..432
     V_segment       96..394
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81695.1"
                     /translation="CVQAIAFPYSF"
     J_segment       395..432
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          102 t
ORIGIN      
        1 acatggggga ggactcctca gttcaccttc tcacaatgag gctccctgct cagttcctgg
       61 ggctgctgat gctctggctc cctgaatcca gtggggatat tgtgatgacc cagactccac
      121 tctccctgtc catcacccct ggagagccgg cctccatctc ctgcaggtct agtcagagcc
      181 tcctgcatag taatggaaac acctatttcc actggtacct gcagaagcca ggccagtctc
      241 cgcagctcct gatttatggg ggttccaaca gagcctctgg agtcccagac aggttcagtg
      301 gcagtgggtc aggcactgat ttcacactga aaatcagcaa ggtggaggcg gaggatgttg
      361 gggtttatta ctgcgtgcaa gctatagcgt ttccgtacag ttttggccag gggaccaaag
      421 tggagatcaa acgag
//
LOCUS       KCVT01004171             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17405:15437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004171
VERSION     KCVT01004171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17405:15437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81696.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004172             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23796:8820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004172
VERSION     KCVT01004172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23796:8820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81697.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattatg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004173             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20261:12882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004173
VERSION     KCVT01004173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20261:12882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81698.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004174             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12771:10603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004174
VERSION     KCVT01004174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12771:10603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81699.1"
                     /translation="CIQALQTPYSF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          118 c          120 g          106 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcac cttgtcacaa tgaggctccc tgctcagctc
       61 ctggggctgc taatgctctg ggtctctgcc tccagtggag atatcgtgat gacccagact
      121 ccactctcgc tgcccgtcac ccttggagag ccagcctcca tctcctgcag gtctagtcag
      181 agccttctga atagtaatgg atacaactat ttgagttggt acctgcagag gccaggccag
      241 tctccacatc ttctgatcta ttatggttct agtcgggcct ccggggtccc cgacaggttc
      301 agtggcagtg ggtcaggcac agattttaca ctgaaaatca gcagggtgga ggctgaggac
      361 gtaggggttt attactgcat tcaagctcta caaaccccgt acagttttgg ccaggggacc
      421 agagtggaga tcaaacgag
//
LOCUS       KCVT01004175             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10610:15560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004175
VERSION     KCVT01004175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10610:15560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81700.1"
                     /translation="CMQGLEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 gctcttggat agtgaggatg aaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcca ttcactttcg gccccgggac
      421 caagctggaa atcaaacgag
//
LOCUS       KCVT01004176             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15563:10647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004176
VERSION     KCVT01004176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15563:10647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..420
                     /note="immunoglobulin light chain variable region"
     V_region        95..420
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81701.1"
                     /translation="CQQRNNYPYMYDF"
     J_segment       391..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          103 a          113 c          110 g           99 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagttgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcaa gtcaggacat
      181 tggcagttat ttggcctggt atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 taaggcgtcc agtttgcaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca ggctgaagat tttgcagttt attactgtca
      361 acagcgtaat aattacccgt acatgtacga ttttggccag gggaccaaag tggagatcaa
      421 gcgag
//
LOCUS       KCVT01004177             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16269:21299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004177
VERSION     KCVT01004177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16269:21299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81702.1"
                     /translation="CMQGLEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          117 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tccagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 acgttggggt ttattactgc atgcaaggtc tagagtttcc attcactttc ggccccggga
      421 ccaagctgga aatcaaacga g
//
LOCUS       KCVT01004178             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:26616:19377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004178
VERSION     KCVT01004178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26616:19377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81703.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc cgctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004179             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16047:11525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004179
VERSION     KCVT01004179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16047:11525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81704.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          117 c          119 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaagctcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcagtctc accatcagta gtctggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004180             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18225:10894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004180
VERSION     KCVT01004180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18225:10894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81705.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccggga ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004181             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11277:7046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004181
VERSION     KCVT01004181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11277:7046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81706.1"
                     /translation="CMQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          118 c          122 g          110 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttgggg agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatgttgag gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtct gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gttttatttc tgcatgcaaa gtctggagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004182             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18998:19111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004182
VERSION     KCVT01004182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18998:19111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81707.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          126 c          111 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa ggtaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004183             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8262:14543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004183
VERSION     KCVT01004183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8262:14543"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81708.1"
                     /translation="CQQHNTYPYTF"
     J_segment       384..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          105 a          119 c          106 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatactta cccgtacact tttggccagg ggaccaaggt ggagatcata
      421 cgag
//
LOCUS       KCVT01004184             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:9590:12759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004184
VERSION     KCVT01004184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9590:12759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81709.1"
                     /translation="CMQALEFPWTF"
     J_segment       407..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           97 a          121 c          123 g          105 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccctgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gattggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctggag tttccttgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004185             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19332:16051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004185
VERSION     KCVT01004185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19332:16051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81710.1"
                     /translation="CQQYNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat
      181 taccaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagtataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01004186             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12727:14936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004186
VERSION     KCVT01004186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12727:14936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81711.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004187             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13757:13675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004187
VERSION     KCVT01004187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13757:13675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81712.1"
                     /translation="CVQAIVFPYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           93 a          119 c          120 g          102 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgtcc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggaaaca cctatttcca ctggtacctg cagaagccag gccagtctcc
      241 gcagcccctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcaag ctatagtgtt tccgtacagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01004188             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18142:15283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004188
VERSION     KCVT01004188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18142:15283"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81713.1"
                     /translation="CEQYNSLPYTF"
     J_segment       269..306
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           89 a           74 c           71 g           75 t
ORIGIN      
        1 acatgggatc ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa
       61 gtcaggacgt taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc
      121 tcctgatcta ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg
      181 gatctgggac agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt
      241 attactgtga acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga
      301 tcaaacgag
//
LOCUS       KCVT01004189             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19512:5051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004189
VERSION     KCVT01004189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19512:5051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81714.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004190             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19137:11078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004190
VERSION     KCVT01004190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19137:11078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81715.1"
                     /translation="CQHSFRTPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          117 c          109 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcaat gtcacttgca gggctagtga
      181 gagcgttagc accaaattac attggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcgtccactt tacaaagtgg ggtcccatca aggttcagcg gcagtggttc
      301 tggaacacat ttcactctca ccatcagcag cctgcagcct gaagatgtcg caacttttta
      361 ctgtcagcat agttttcgta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004191             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8236:4267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004191
VERSION     KCVT01004191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8236:4267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81716.1"
                     /translation="CMQALEFPRTF"
     J_segment       402..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          123 c          122 g           97 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg gccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggct agagaggatg gaaacaccta tttggactgg tacctgcaga ggccaggcca
      241 gactccccag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacagggt
      301 cagaggcagt gggtcagaca ctgagttcac actgaaaatc agcagagtgg aggctgagga
      361 tcttgggatt tattactgca tgcaagctct agagtttcct cggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004192             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13379:10991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004192
VERSION     KCVT01004192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13379:10991"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..319
                     /note="immunoglobulin light chain variable region"
     V_region        8..319
     V_segment       8..276
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81717.1"
                     /translation="CQQGYSYPYSF"
     J_segment       282..319
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           82 a           87 c           78 g           75 t
ORIGIN      
        1 acatgggtga cgcagtctcc atcctccctg tccgcatctg caggagacac agtcaccatc
       61 acttgccagg cgagtcaagg cattggcaat actttaaatt ggtatcaaca gaaaccgggg
      121 aaagccccta cactcctgat ctatagggca tccggtttgc aaaatgggac tccctctcgg
      181 ttcagcggca gtggatctgg gacggatttc actctcacca tcagcagcct gcagcctgaa
      241 gattttgcca cttattactg tcaacagggt tatagttatc cgtacagttt tggccagggg
      301 accaaactgg agatcaaacg ag
//
LOCUS       KCVT01004193             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12715:11527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004193
VERSION     KCVT01004193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12715:11527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81718.1"
                     /translation="CMQSLDFPLTF"
     J_segment       404..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtt atgacccaga
      121 ctccattctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccaggca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggagactg
      361 aggatgttgg ggtttattac tgcatgcagt ctctagattt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaat cgag
//
LOCUS       KCVT01004194             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11235:17658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004194
VERSION     KCVT01004194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11235:17658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81719.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accaggaaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004195             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:12645:3444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004195
VERSION     KCVT01004195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12645:3444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81720.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggtc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004196             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12238:17385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004196
VERSION     KCVT01004196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12238:17385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..406
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81721.1"
                     /translation="CQQYNSDPYSF"
     J_segment       407..444
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          114 a          116 c          119 g           98 t
ORIGIN      
        1 acatggggga ggctaggcac gcttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca ggtgccaatt
      121 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      181 ccatcacttg tcgggcgagt caggacatta ggaattattt agcgtggtat cagcagaaac
      241 cagggaaagc cccgaaggcc ttgatctatt acacatccat tttggaaaat ggggtcccat
      301 caaggttcag cggcggtgga tctgggacag aattcagtct caccatcagc agcctgcagg
      361 ctgaggattt tgcaacttat tactgtcaac agtataacag tgacccgtac agttttggcc
      421 aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01004197             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:5965:10757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004197
VERSION     KCVT01004197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5965:10757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81722.1"
                     /translation="CMQTLEFPLTF"
     J_segment       276..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           80 c           89 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagtctc
      121 cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa actctagagt ttcctctcac tttcggcgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01004198             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18900:16478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004198
VERSION     KCVT01004198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18900:16478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81723.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          121 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgcttt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004199             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14508:3722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004199
VERSION     KCVT01004199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14508:3722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-82"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81724.1"
                     /translation="CMQGTHLPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          126 c          118 g          102 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctggggct gttagtgctc tggctccctg ggtccactgg cgacactgtg atgacacaga
      121 ccccactctc cctgcccgtc acccctggag agccggcctc catctcctgt aggtctagtc
      181 agagcctcct acatagaaat ggatacacct atttgtactg gtacctgcag aggccgggcc
      241 agtctccaca gctcctgatg tattttgttt caaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactacgaat cagcagggtg gaggctgagg
      361 atattgggat ttattattgc atgcaaggta cacaccttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004200             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:13380:16789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004200
VERSION     KCVT01004200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13380:16789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..270
                     /note="immunoglobulin light chain variable region"
     V_region        7..270
     V_segment       7..234
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <213..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81725.1"
                     /translation="CMQGTQLLTF"
     J_segment       235..270
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>273
                     /gene="IGKC"
BASE COUNT           77 a           60 c           77 g           59 t
ORIGIN      
        1 acatggggtc tagtcaaagc cttctacaca ctgatgggaa aacctacttg aattggtatc
       61 agcagaagcc aggccaacct ccaaggcgcc taatttatca ggtttctaac cgggactctg
      121 gggtcccaga cagattcagc ggcagtgggg cagggacaga tttcacactg aaaatcagca
      181 gagtggagac tgaggatgtt ggagtttatt actgcatgca aggtacacag cttctcactt
      241 tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004201             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13660:3095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004201
VERSION     KCVT01004201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13660:3095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81726.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcgtcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004202             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23700:12523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004202
VERSION     KCVT01004202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23700:12523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..382
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81727.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       388..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g          101 t
ORIGIN      
        1 acatggggag ttagacccag tctggacgca gcatggacat cagggtcctc gctcagcttc
       61 tcgggctcct gctgctctgg ctcccaggtg ccagatgtga cactcagttg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg acaagtcagg
      181 acattagcag ttatttagcc tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctataaggc gtccagtttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaggctga agattttgca gtttattact
      361 gtcaacagcg tattggttac ccgtacatgt acagttttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01004203             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9958:4719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004203
VERSION     KCVT01004203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9958:4719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81728.1"
                     /translation="YMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactac atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004204             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:25753:18656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004204
VERSION     KCVT01004204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25753:18656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81729.1"
                     /translation="CLQYKTFPYTF"
     J_segment       387..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          118 c          100 g           97 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggggacactg tcaccatcac ttgccggaca agtcaaggta
      181 ttaccaatta tttacattgg tttcagcaga aaccagggag agcccctaag ctcctgatct
      241 atgagacatc cagtttgaca agtggggtcc catcaaggtt cagcggcagt gcatctggga
      301 cagaattcac tctcaccatc accagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtataa aactttcccg tacacctttg gccaggggac cagactggag atcaaacgag
//
LOCUS       KCVT01004205             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17664:13846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004205
VERSION     KCVT01004205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17664:13846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..445
                     /note="immunoglobulin light chain variable region"
     V_region        106..445
     V_segment       106..407
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81730.1"
                     /translation="CQQYYGSPYSF"
     J_segment       408..445
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT          110 a          114 c          117 g          107 t
ORIGIN      
        1 acatggggac aacaggcagg caggggcagc aagatggtgt cacagaccca agtcttcatt
       61 tccctgttgc tctggatctc tgtgtccatt gcaggtgcct ctggggacat tgtgatgacc
      121 cagtctccgg actccctggc tgtgtctctg ggagagaaaa ttaccatcaa ctgcaagtcc
      181 agccagagtc tttcatacat ctccaacaat aagaaatact tagcctggta ccagcagaaa
      241 ccaggacagg ctcctaagct gctcatttac tgggcatcta cccgggagtc cggtgtccct
      301 aaccgattca gtggcagtgg atctgggtca gatttcactc tcaccatcag tgacctgcag
      361 gctgaagatg tggcagttta ttactgtcag cagtattatg gcagtccgta cagttttggc
      421 caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01004206             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23546:12224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004206
VERSION     KCVT01004206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23546:12224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81731.1"
                     /translation="CMQPLEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactgtc cctgcccgtc acccttggag agccggcctc catctcctgt gggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004207             377 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9780:14638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004207
VERSION     KCVT01004207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 377)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9780:14638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    199..374
                     /note="immunoglobulin light chain variable region"
     V_region        199..374
     V_segment       199..332
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <314..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81732.1"
                     /translation="CQQYNSDSLTF"
     J_segment       337..374
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        375..>377
                     /gene="IGKC"
BASE COUNT           92 a           82 c          122 g           81 t
ORIGIN      
        1 acatggggcc gctgcggtga gccttgaagc ctagggcgtg ggcccgggtg gagccgccgc
       61 aggtgcagat cttggtggta gtagcaaata ttcaaacgag aactttgaag gccgaagtgg
      121 agaagggttc catgtgaaca gcagttgaac atgggtcagt cggtcctgag agatgggcga
      181 gcgccgttcc gaagggactt acgcatccgt tttggaaagt ggggtcccat caagattcag
      241 cggtagtgga tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt
      301 tggaacttat tactgtcaac agtataacag tgactcgctc actttcggtg gagggaccaa
      361 ggtggagatc aaacgag
//
LOCUS       KCVT01004208             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23200:8992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004208
VERSION     KCVT01004208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23200:8992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..401
                     /note="immunoglobulin light chain variable region"
     V_region        110..401
     V_segment       110..363
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81733.1"
                     /translation="CMQPLEFPWTF"
     J_segment       364..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           96 a          103 c          111 g           94 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 catctcctgc aggtctagtc agagcctcct ggatagtgag gatggaaaca cctatttgga
      181 atggtaccta cagaagccag gccagtctcc acagctcttg atttatgagg tttccaaccg
      241 ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa
      301 aatcagcaga gtggaggctg aggatattgg ggtttattac tgcatgcaac ctctagagtt
      361 tccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004209             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17262:11684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004209
VERSION     KCVT01004209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17262:11684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81734.1"
                     /translation="CQQHDNAPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          116 c          113 g           86 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagag
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaggccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtgtatctgg
      301 gacagatttc actctcagca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcagcagcat gacaatgccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004210             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13222:20589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004210
VERSION     KCVT01004210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13222:20589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..365
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81735.1"
                     /translation="CLQGDTAPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          114 c          112 g           93 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cttccctgtc tgcatcggca ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttaacgatta tttaagttgg tatcagcaga aaccaggaaa acctcctaag cgcctgattt
      241 atgctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcagct tattactgtc
      361 tacagggtga tactgccccg ttcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004211             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12138:4828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004211
VERSION     KCVT01004211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12138:4828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81736.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004212             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22104:4391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004212
VERSION     KCVT01004212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22104:4391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81737.1"
                     /translation="CMQYRHIPFTF"
     J_segment       312..349
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           85 a           89 c           93 g           85 t
ORIGIN      
        1 acatgggggg atgttgtgat gacccagact ccattctccc tgtccgttag ccctggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttga atagtgaaga cggaaacacc
      121 tatttggatt ggtacctgca gaggccgggc cagtctccac agcccttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa ttaacagagt ggaggctgag gatgttggga tttatatctg catgcaatat
      301 agacacattc cattcacttt cggccccggg accaaactgg atatcaaacg ag
//
LOCUS       KCVT01004213             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15583:13012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004213
VERSION     KCVT01004213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15583:13012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81738.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          125 c          112 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgatgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004214             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18963:12437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004214
VERSION     KCVT01004214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18963:12437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81739.1"
                     /translation="CQQHNTYPLTF"
     J_segment       390..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          117 c          104 g           95 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 aggacattag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatgtatta cgcatccaat ttggaaaatg gggtcccatc aaggttcagt ggtagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaagttatt
      361 actgtcaaca gcataatact tacccattga ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01004215             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16123:17048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004215
VERSION     KCVT01004215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16123:17048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81740.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccattgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004216             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:8697:5943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004216
VERSION     KCVT01004216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8697:5943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81741.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc atcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004217             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6607:13543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004217
VERSION     KCVT01004217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6607:13543"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81742.1"
                     /translation="CLQGYIDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          113 c          113 g           99 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtcggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttgcaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 actgtctaca gggttatatt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004218             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4316:14392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004218
VERSION     KCVT01004218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4316:14392"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81743.1"
                     /translation="CEQYNSLPYTF"
     J_segment       367..404
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT          107 a          108 c           97 g           95 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tcctgctgct
       61 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct ccctgtctgc
      121 ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacatta acatttattt
      181 aaattggtat caccagaaac cggggaaagc ccctaagctc ctgatctatt atacaaaccg
      241 tttggaaact ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcaac ctgaagattt tgcaacttat tactgtgaac aatacaatag
      361 tttaccgtac acttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01004219             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15135:7046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004219
VERSION     KCVT01004219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15135:7046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81744.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag agagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004220             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11636:10341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004220
VERSION     KCVT01004220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11636:10341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81745.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtgtcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004221             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13263:18968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004221
VERSION     KCVT01004221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13263:18968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81746.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccaggct
      121 ccactctccc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004222             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18394:13384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004222
VERSION     KCVT01004222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18394:13384"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81747.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          102 a          127 c          120 g           87 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 ctgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct
      241 cccagactcc tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt
      301 ggcagtgggt ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt
      361 gcactttatt attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01004223             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14136:12975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004223
VERSION     KCVT01004223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14136:12975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..406
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81748.1"
                     /translation="CQQHDDSPRTF"
     J_segment       408..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          115 a          124 c          117 g           90 t
ORIGIN      
        1 acatggggag actggtcaca ccctgtgcag gagtcagtct cagacaggac acagcatgga
       61 cacgagggtc cccgctcagc tcctggggct cctgttgctc tggctcccag gtgccagatg
      121 tgacatccag ctgacccagt ctccaccctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgc agagccagtc aggatattaa caactggttg gcctggtatc aacagaaacc
      241 agggaaagcc cctaaggtcc tgatctatag ggcatccaat ttggaaacag gggtcccatc
      301 aaggttcagt ggaagtggat ctgggacaga tttcactctc accatcagca gcctgcagcc
      361 tgaagatatc gcaacatatt actgtcaaca gcatgatgat tcgcctcgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004224             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11698:13162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004224
VERSION     KCVT01004224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11698:13162"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..384
                     /note="immunoglobulin light chain variable region"
     V_region        64..384
     V_segment       64..348
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81749.1"
                     /translation="CLQYKTYPLTF"
     J_segment       349..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>388
                     /gene="IGKC"
BASE COUNT           91 a          107 c           94 g           96 t
ORIGIN      
        1 acatgggggg cccccgctca tctcctaggg ctcttgctgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgactca gtctccatct tccctgtctg catctgtagg agacactgtc
      121 accatcactt gccgggcaag tcagggtatt agcacttatt taagttactt tcagcagaaa
      181 ccagggaaag cccctagact cctgatctat gctgcatcca gtttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gatttcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta tcactgtcta cagtataaaa cttaccctct cactttcggc
      361 ggggggacca aggtggagat caaaagag
//
LOCUS       KCVT01004225             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7206:12231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004225
VERSION     KCVT01004225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7206:12231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81750.1"
                     /translation="CQQDLDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          127 c          112 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagcctc cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacagacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gttttctctc accatcagca gcctggagcc tgaagatgtt gcaatttatt
      361 actgtcagca ggatttggac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgat
//
LOCUS       KCVT01004226             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16969:7813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004226
VERSION     KCVT01004226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16969:7813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81751.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccccggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tcgagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004227             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16610:8247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004227
VERSION     KCVT01004227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16610:8247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81752.1"
                     /translation="CMQGLEFPITF"
     J_segment       402..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          102 a          120 c          111 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg agtctgaaga
      361 tgttgggatt tattattgca tgcaaggtct agagtttcca atcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01004228             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23915:14491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004228
VERSION     KCVT01004228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23915:14491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81753.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          116 c          103 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaactat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt ctctctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01004229             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:15018:10600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004229
VERSION     KCVT01004229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15018:10600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81754.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          127 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 ctctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgctttca cactgcaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004230             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23555:13892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004230
VERSION     KCVT01004230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23555:13892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81755.1"
                     /translation="CHQYNNLPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          114 c          103 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgc aaatcgtttg gaaactgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacccga agattttgca acttattact
      361 gtcaccagta taataattta ccactcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004231             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:23229:6542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004231
VERSION     KCVT01004231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23229:6542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..398
                     /note="immunoglobulin light chain variable region"
     V_region        80..398
     V_segment       80..364
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81756.1"
                     /translation="CQQYNRLPRTF"
     J_segment       366..398
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>404
                     /gene="IGKC"
BASE COUNT           99 a          108 c          105 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag ggcattagtc aatatttaaa
      181 ttggtatcag cagaaagcgg ggaaagcccc taggctcctc atctattatg taaaccgtct
      241 ggaaactggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaacctg aggattttgc aacttattac tgtcagcagt ataatcgttt
      361 acctcggacg ttcggccaag ggaccaaggt ggaaatcaga cgag
//
LOCUS       KCVT01004232             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5313:11829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004232
VERSION     KCVT01004232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5313:11829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..301
                     /note="immunoglobulin light chain variable region"
     V_region        7..301
     V_segment       7..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <241..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81757.1"
                     /translation="CMQALEFPWTF"
     J_segment       265..301
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>304
                     /gene="IGKC"
BASE COUNT           73 a           69 c           91 g           71 t
ORIGIN      
        1 acatggggag agccggcctc catctcctgc aggtctagtc agagcctctt ggatagtgag
       61 gatggaaaca cctatttgga ttggtacctg cagaagccag gccagtctcc acagctcttg
      121 atttatgagg tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca
      181 gacactgatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg ggtttattac
      241 tgcatgcaag ctctggagtt tccttggacg ttcggccaag ggaccaaggt ggaaatcaaa
      301 cgag
//
LOCUS       KCVT01004233             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12242:3986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004233
VERSION     KCVT01004233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12242:3986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81758.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          119 c          106 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgttggag acacagtcac catcacttgt cgggcaagtc
      181 aggacattac gaatgattta gcctggtatc aacagaaacc aagtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004234             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11095:7989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004234
VERSION     KCVT01004234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11095:7989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81759.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004235             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6802:15595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004235
VERSION     KCVT01004235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6802:15595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81760.1"
                     /translation="CMQGLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          126 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggtt ggagacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtgt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004236             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16430:9468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004236
VERSION     KCVT01004236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16430:9468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81761.1"
                     /translation="CQQHNTYPLTF"
     J_segment       389..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          118 c          105 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 ggacattagt aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatgtattac gcatccaatt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caagttatta
      361 ctgtcaacag cataatactt acccattgac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01004237             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21859:17048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004237
VERSION     KCVT01004237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21859:17048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..328
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81762.1"
                     /translation="CQQYNSLPYSF"
     J_segment       329..366
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           92 a           91 c           95 g           91 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc
       61 agtctccatc ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa
      121 gtcagggcgt taacgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc
      181 ccctgatctt ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt
      301 attattgtca acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga
      361 tcaaacgag
//
LOCUS       KCVT01004238             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16323:5594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004238
VERSION     KCVT01004238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16323:5594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81763.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggcgagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaagcga g
//
LOCUS       KCVT01004239             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23335:9127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004239
VERSION     KCVT01004239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23335:9127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81764.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          126 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggtgcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004240             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13830:17734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004240
VERSION     KCVT01004240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13830:17734"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..363
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81765.1"
                     /translation="CLQGDTAPFTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          100 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctccttctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatct
      121 tccctgtctg catcggcagg agacagagtc accatcactt gccgggcaag tcagggcatt
      181 aacgattatt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg cctgatttat
      241 gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcagctta ttactgtcta
      361 cagggtgata ctgccccgtt cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01004241             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16519:9452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004241
VERSION     KCVT01004241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16519:9452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..406
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81766.1"
                     /translation="CQQYDSDPFTF"
     J_segment       409..444
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          109 a          122 c          119 g           97 t
ORIGIN      
        1 acatggggga ggctaggcac gcttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca ggtgccaaat
      121 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      181 ccatcacttg tcgggcgagt cagggcattc gcagttattt agcgtggtat cagcagaaac
      241 cagggaaagc cccgaagccc ttgatctatt acgcgtccac tttggaaagt ggggtcccat
      301 caaggttcag cggcagtgga tctgggacag aattcactct caccatcagc agcctgcagc
      361 ctgaagattt tgcaacttat tactgtcaac agtatgacag tgacccgttc actttcggtg
      421 gagggaccaa ggtagagatc aaacgag
//
LOCUS       KCVT01004242             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11243:13883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004242
VERSION     KCVT01004242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11243:13883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81767.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          123 c          123 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01004243             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13762:2605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004243
VERSION     KCVT01004243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13762:2605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..435
                     /note="immunoglobulin light chain variable region"
     V_region        100..435
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81768.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>442
                     /gene="IGKC"
BASE COUNT           95 a          123 c          119 g          105 t
ORIGIN      
        1 atggggactg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgta tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgcgga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccagggg
      421 accaaggtgg aaatcgaacg ag
//
LOCUS       KCVT01004244             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21054:8196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004244
VERSION     KCVT01004244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21054:8196"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..367
                     /note="immunoglobulin light chain variable region"
     V_region        87..367
     V_segment       87..327
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81769.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       335..367
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           99 a           90 c           92 g           89 t
ORIGIN      
        1 acatggggaa gtcagaacca ctcaggacac aggatggaca tgacggtccc cgcttatctc
       61 ctggggctcc ttctgctctg gctcccagga gacaaagtca ccatcacttg cagggcaagt
      121 caggacattg gtaattattt aaattggtat cagcagaaac caggaaaagc tcctaaggtc
      181 ctgatctatg gtgtatccaa tttacaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag atcttactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      301 tattgtcaac cgtttaaaag ttacctttcg gtccctttcg gcggagggac caaggtggag
      361 atcaaacgag
//
LOCUS       KCVT01004245             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11417:2757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004245
VERSION     KCVT01004245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11417:2757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81770.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catgtatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004246             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10341:11303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004246
VERSION     KCVT01004246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10341:11303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81771.1"
                     /translation="CQQYNSLPLSF"
     J_segment       388..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          112 c          104 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccaaatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gcaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttttttaaat tggtatcagc agaaaccggg gaaagcccct aagatcctga
      241 tctactatgg aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcaacctga ggattttgga gtttattatt
      361 gtcaacaata taatagttta ccactctctt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004247             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:5590:8195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004247
VERSION     KCVT01004247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5590:8195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..423
                     /note="immunoglobulin light chain variable region"
     V_region        96..423
     V_segment       96..373
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81772.1"
                     /translation="CQHRNRKPYMNTF"
     J_segment       392..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          115 c          108 g           97 t
ORIGIN      
        1 acatggggga gacccagtct ggacgcagca tggacatcag ggtcctcgct cagcttctcg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagttgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tctccatcac ttgtcgggca agtcagggca
      181 ttagcactga tttagcctgg tatcagcaga aaccagggaa agcccctaac ctcctgatct
      241 ataaggcgtc cagtttgcaa aatggggtcc catcaaggtt cagtggcact ggatctgaga
      301 cagaattcac actcgccatc agcagcctgc agcctgaaga ttttgtagtt tattactgtc
      361 aacaccgtaa tagaaagccg tacatgaaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004248             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8658:6302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004248
VERSION     KCVT01004248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8658:6302"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81773.1"
                     /translation="CQQGYGFPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          120 c          104 g          103 t
ORIGIN      
        1 acatggggag tcagtcagtc tcagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctccttgggc tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacgcag
      121 tctccatcct ccctgtccgc atctgtagga gacacagtcg cgatcacttg cctggcgagt
      181 caaggcattg gcaataattt aaattggtat cagcagaaac cagggaaagc ccctaaactc
      241 ctgatctata cggcatccaa tttacatggt gggattccct ctcggttcag cggcagtgga
      301 tctgggacgg atttcactct caccatcaac agcctgcagc ctgaagattt tgccacttat
      361 tactgtcaac agggttatgg ttttccattc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01004249             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13526:13970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004249
VERSION     KCVT01004249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13526:13970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81774.1"
                     /translation="CLQYNSSPLTF"
     J_segment       269..306
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           80 a           81 c           78 g           70 t
ORIGIN      
        1 acatgggatc ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcga
       61 gtcagactat tagcagctgg ttagactggt atcagcagaa accagggaaa gcccctaacc
      121 tcctgatctt taaggcatcc agtttgcaaa gtggggtccc ctcaaggttc agcggcagtg
      181 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      241 attattgtct acagtacaat agtagcccgc tcactttcgg cggagggacc aaggtggaga
      301 tcaaacgag
//
LOCUS       KCVT01004250             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25354:14817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004250
VERSION     KCVT01004250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25354:14817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81775.1"
                     /translation="CQQDYSWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          120 c          118 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tgtcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcatcttag cctggtacca ccagaaacct gggcaggctc ccaagtccct
      241 catctatggt gcaaccagta gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gcgtttatta
      361 ctgtcagcag gattatagct ggccactcac tttcggcgga gggaccaagg tggggatcaa
      421 acgag
//
LOCUS       KCVT01004251             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12016:18359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004251
VERSION     KCVT01004251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12016:18359"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..446
                     /note="immunoglobulin light chain variable region"
     V_region        104..446
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81776.1"
                     /translation="CMQALEFPPFTF"
     J_segment       409..446
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>449
                     /gene="IGKC"
BASE COUNT           96 a          127 c          118 g          108 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 ggctccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggacagtg aggatggaaa cacctatttg gaatggttcc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aacatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt attgcatgca agctctagag tttcctccat tcactttcgg
      421 ccccgggacc aaactggaaa tcaaacgag
//
LOCUS       KCVT01004252             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12360:21521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004252
VERSION     KCVT01004252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12360:21521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81777.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          117 g          105 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctggag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004253             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10082:19564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004253
VERSION     KCVT01004253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10082:19564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81778.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          118 c          107 g           90 t
ORIGIN      
        1 atgggggagt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004254             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10366:6613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004254
VERSION     KCVT01004254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10366:6613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81779.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          119 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg gccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctctagag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004255             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8752:10197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004255
VERSION     KCVT01004255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8752:10197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81780.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004256             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13800:8272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004256
VERSION     KCVT01004256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13800:8272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81781.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004257             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22012:11216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004257
VERSION     KCVT01004257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22012:11216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..426
                     /note="immunoglobulin light chain variable region"
     V_region        90..426
     V_segment       90..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81782.1"
                     /translation="CMQGTHLPFTF"
     J_segment       389..426
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           99 a          119 c          109 g          102 t
ORIGIN      
        1 acatggggat caggactcct cagttcacca tgaggctccc tgctcagctc ctggggctgc
       61 tattgctctg cgtccccgga tccagtgggg atgttgtgat gactcagtct ccactctccc
      121 tgtctatcac tcttggacaa ccggcctcca tttcctgcag gtctagtcac acccttgtac
      181 acagtgatgg gaaaacctac ttgaattggt atcagcagaa gccaggccaa cctccaaggc
      241 gcctaattta tcaggtttct aaccgggact ctggggtccc agacagattc agcggcagtg
      301 gggcagggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttggagttt
      361 attactgcat gcaaggtaca caccttccat tcactttcgg ccccgggacc aaactggata
      421 tcaaacgag
//
LOCUS       KCVT01004258             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9742:13003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004258
VERSION     KCVT01004258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9742:13003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81783.1"
                     /translation="CMQALDFPWTF"
     J_segment       398..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          102 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaagatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga ctttccttgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01004259             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14474:13422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004259
VERSION     KCVT01004259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14474:13422"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81784.1"
                     /translation="CQQGYSFPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           95 a          123 c          106 g          100 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca gtagtttaag ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctttaggg catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctccagcctg aagatttttc cacttattac
      361 tgtcaacagg gttatagttt ccccttcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01004260             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21776:8278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004260
VERSION     KCVT01004260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21776:8278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    24..310
                     /note="immunoglobulin light chain variable region"
     V_region        24..310
     V_segment       24..273
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81785.1"
                     /translation="CMQTLEFPLTF"
     J_segment       274..310
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>313
                     /gene="IGKC"
BASE COUNT           75 a           73 c           90 g           75 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc atctcctgca ggtctagtca gagcctcttg
       61 gatggtgagg atggaaacac ctatttggat tggtacctgc agaagccagg ccagtctcca
      121 cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag gttcagtggc
      181 agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      241 gtttattact gcatgcaaac tctagagttt cctctcactt tcggcggagg gaccaaggtg
      301 gagatcaaac gag
//
LOCUS       KCVT01004261             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:4118:20196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004261
VERSION     KCVT01004261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:4118:20196"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81786.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          122 c          110 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgctctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01004262             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10765:7362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004262
VERSION     KCVT01004262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10765:7362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81787.1"
                     /translation="CMQALEFPWTF"
     J_segment       398..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          103 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccagt
      121 ctccctgccc gtcaccctgg gagagccggc ctccatctcc tgccggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggcac ctgcagaggc caggccagtc
      241 tccacagctc ttgatttatg aggtttccta tcgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggtatttat tactgcatgc aagctctaga gtttccttgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01004263             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11013:13844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004263
VERSION     KCVT01004263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11013:13844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81788.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctctct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004264             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15286:8094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004264
VERSION     KCVT01004264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15286:8094"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81789.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccatcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004265             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:23812:18003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004265
VERSION     KCVT01004265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23812:18003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..355
                     /note="immunoglobulin light chain variable region"
     V_region        16..355
     V_segment       16..317
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <295..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81790.1"
                     /translation="CMQYRHIPFTF"
     J_segment       318..355
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>358
                     /gene="IGKC"
BASE COUNT           86 a           91 c           95 g           86 t
ORIGIN      
        1 acatgggcca gtggggatgt tgtgatgacc cagactccat tctccctgtc cgttagccct
       61 ggagagccgg cctccatctc ctgcaggtct agtcagagcc tcttgaatag tgaagacgga
      121 aacacctatt tggattggta cctgcagagg ccgggccagt ctccacagcc cttgatttat
      181 gaggtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact
      241 gatttcacac tgaaaattaa cagagtggag gctgaggatg ttgggattta tatctgcatg
      301 caatatagac acattccatt cactttcggc cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01004266             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19988:15085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004266
VERSION     KCVT01004266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19988:15085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81791.1"
                     /translation="CQQGYTYLYSF"
     J_segment       379..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          117 c          103 g           98 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgtt ggagacacag tcaccatcac ttgccaggcg agtcaggcca
      181 ttgccaataa tttaaattgg tatcagcaga aaccaggaaa agcccctaaa gtcctaatct
      241 ataaggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcgccctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tacttacctg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004267             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19819:10320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004267
VERSION     KCVT01004267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19819:10320"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81792.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          109 c          109 g           99 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attgagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cgttaacgtt tatttaaatt ggtatcaaca gaaaccgggg aaagccccta agcccctgat
      241 cttttatgca aaccgtttgg aacgtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa gttattattg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004268             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21259:4218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004268
VERSION     KCVT01004268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21259:4218"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81793.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtac tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagagacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004269             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:24414:13311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004269
VERSION     KCVT01004269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24414:13311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81794.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcaacagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004270             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8065:4928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004270
VERSION     KCVT01004270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8065:4928"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81795.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          115 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttccc cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gtctggagcc tgaagatgtt gcactttatt
      361 actgtcaaca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004271             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10252:18406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004271
VERSION     KCVT01004271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10252:18406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81796.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          118 c          104 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgtt ggagacacag tcaccatcac ttgtcgggca agtcaggaca
      181 ttacgaatga tttagcctgg tatcaacaga aaccaagtaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01004272             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:24035:11938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004272
VERSION     KCVT01004272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24035:11938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81797.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagttcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004273             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7607:2562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004273
VERSION     KCVT01004273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7607:2562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81798.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004274             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:25404:7759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004274
VERSION     KCVT01004274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25404:7759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81799.1"
                     /translation="CQQYDKSPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          117 g           86 t
ORIGIN      
        1 atggggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gggtcaccat cacttgcaga gccagtcagg
      181 gtatcagcaa ctggttggcc tggtatcaac agaaaccagg gagagcccct aacctcctga
      241 tgtatagggc gtccaatttg caaggagggg tcccatcaag gttcagagga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga ggatgtcgct acatattact
      361 gtcaacagta tgataagtcc cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004275             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22742:16133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004275
VERSION     KCVT01004275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22742:16133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81800.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcgaccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004276             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23053:12189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004276
VERSION     KCVT01004276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23053:12189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81801.1"
                     /translation="CMQSLEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ctccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaga atcagtagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaatc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004277             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10156:4311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004277
VERSION     KCVT01004277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10156:4311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81802.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgagattt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcacagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004278             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14922:13178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004278
VERSION     KCVT01004278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14922:13178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..414
                     /note="immunoglobulin light chain variable region"
     V_region        97..414
     V_segment       97..380
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81803.1"
                     /translation="CLQGYSAPFTF"
     J_segment       381..414
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>421
                     /gene="IGKC"
BASE COUNT          100 a          119 c          105 g           97 t
ORIGIN      
        1 actgggagtc agaaccactc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctccttc tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcttccctgt ctgcttcggt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 attagcgatt atttaagttg gtatcagcag aaaccaggaa aaactcctca gcgcctgatc
      241 tatgctgcat ccagtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcagc ttattactgt
      361 ctacagggtt atagtgcccc attcactttc ggccccggga ccaaactgga tatccaacga
      421 g
//
LOCUS       KCVT01004279             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:24777:8486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004279
VERSION     KCVT01004279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:24777:8486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..245
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81804.1"
                     /translation="CQQYDSDSLTF"
     J_segment       250..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           77 a           69 c           79 g           65 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgtcgggcg actcaggaca ttcgcagtta
       61 tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc
      121 cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtatga
      241 cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004280             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8561:13850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004280
VERSION     KCVT01004280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8561:13850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81805.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaggctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004281             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22462:15889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004281
VERSION     KCVT01004281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22462:15889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81806.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          112 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg cccccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcgt ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004282             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24739:9101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004282
VERSION     KCVT01004282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24739:9101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81807.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct cagttcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaataccta tttggaatgg caccggcaga tgccagggca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctgacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004283             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5034:13462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004283
VERSION     KCVT01004283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5034:13462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81808.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgtgc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01004284             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6733:16209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004284
VERSION     KCVT01004284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6733:16209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81809.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004285             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16935:18783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004285
VERSION     KCVT01004285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16935:18783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81810.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcaaca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004286             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18780:6476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004286
VERSION     KCVT01004286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18780:6476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..417
                     /note="immunoglobulin light chain variable region"
     V_region        104..417
     V_segment       104..388
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81811.1"
                     /translation="CLQYSESPLSF"
     J_segment       393..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>428
                     /gene="IGKC"
BASE COUNT          100 a          118 c          112 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacacagtc accatcactt gccgggcgag
      181 tcagactatt cgcagttggt taaactggtt tcaacagaag tcaggaaaag cccctaaact
      241 cctgatctat agggcgtcca ttttacaaag tggagtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcaa cctgaagatt ttgcgactta
      361 cttctgtcta cagtatagtg agagccctct ctctttcggc ggggggacca aggtggacat
      421 tagacgag
//
LOCUS       KCVT01004287             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20772:3134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004287
VERSION     KCVT01004287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20772:3134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..366
                     /note="immunoglobulin light chain variable region"
     V_region        45..366
     V_segment       45..328
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81812.1"
                     /translation="CEQYNSLPYTF"
     J_segment       329..366
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           99 a           94 c           87 g           89 t
ORIGIN      
        1 acatgggggg gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc
       61 agtctccatc ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa
      121 gtcaggacat taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc
      181 tcctgatcta ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt
      301 attactgtga acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga
      361 tcaaacgag
//
LOCUS       KCVT01004288             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:26555:8265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004288
VERSION     KCVT01004288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26555:8265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..367
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81813.1"
                     /translation="CQQHESYPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          123 c          102 g           88 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcacgacat
      181 tagcgattct ttagcctggt atcagcacaa accaggaaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttgaaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaacct attactgtca
      361 acagcatgaa tcttacccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004289             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9268:8827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004289
VERSION     KCVT01004289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9268:8827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81814.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag gtcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004290             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14236:3340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004290
VERSION     KCVT01004290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14236:3340"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81815.1"
                     /translation="CQQYNSLPYIF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          109 c          106 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcat catcacttgc cgggcaagtc
      181 aggacattaa cgtttattta aattggtatc agcagaaacc ggggaaagcc cctaaacccc
      241 tgatctatta tagaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtcaaca gtataatagt ttaccgtaca tttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004291             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15096:13748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004291
VERSION     KCVT01004291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15096:13748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81816.1"
                     /translation="CLQGDSTPFTF"
     J_segment       389..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          102 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccggg aaaagctcct aagcgcctaa
      241 tctatgctgc atccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg tgatagtacc ccgttcactt ttggccaggg gaccaaagtg gacgtcaaac
      421 gag
//
LOCUS       KCVT01004292             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15860:21336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004292
VERSION     KCVT01004292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15860:21336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..351
                     /note="immunoglobulin light chain variable region"
     V_region        12..351
     V_segment       12..313
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <291..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81817.1"
                     /translation="CMQARDFPFTF"
     J_segment       314..351
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>354
                     /gene="IGKC"
BASE COUNT           79 a           94 c          101 g           80 t
ORIGIN      
        1 acatgggggg ggacattgtg atgacccaga ctccactctc cctgcccgtc acccttggag
       61 agccggcctc catctcctgc aggtctagtc agagcctctt cgatagtgag gaaggaaaca
      121 cctatttgga gtggtacctg cagaggccag gccagtctcc acaggtcttg atttatgggg
      181 tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt
      241 tcacactgag aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaag
      301 ctcgagactt tccattcact ttcggccccg ggaccaaact ggacatcaaa cgag
//
LOCUS       KCVT01004293             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8022:8164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004293
VERSION     KCVT01004293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8022:8164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..413
                     /note="immunoglobulin light chain variable region"
     V_region        94..413
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81818.1"
                     /translation="CLQFKSYPNSF"
     J_segment       380..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>418
                     /gene="IGKC"
BASE COUNT          100 a          115 c          105 g           98 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcagggtatt
      181 agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctaagct cctcatctat
      241 gctgcatcca ctttggccgg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtttaaaa gttacccgaa cagttttggc caggggacca aagtggagat caagcgag
//
LOCUS       KCVT01004294             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14241:14876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004294
VERSION     KCVT01004294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14241:14876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81819.1"
                     /translation="CQQHDNSPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          116 c          113 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 agagtattaa cgactggttg gcctggtatc aacagagacc agggaaggcc cctaagctcc
      241 tgatctatag ggcatcccat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagct tgaagatatc gcaacatatt
      361 actgtcaaca gcatgataat tccccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004295             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15431:6491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004295
VERSION     KCVT01004295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15431:6491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81820.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           94 a          117 c          120 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtaga tcaaacgag
//
LOCUS       KCVT01004296             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20411:15244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004296
VERSION     KCVT01004296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20411:15244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81821.1"
                     /translation="CMQALDFPLTF"
     J_segment       276..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           82 c           89 g           75 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gcggatgttg
      241 gggtttatta ctgcatgcaa gctctagact ttcccctcac tttcggcgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01004297             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13706:10826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004297
VERSION     KCVT01004297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13706:10826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81822.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004298             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:11040:17334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004298
VERSION     KCVT01004298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11040:17334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..409
                     /note="immunoglobulin light chain variable region"
     V_region        95..409
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81823.1"
                     /translation="CQQYNTLPLTF"
     J_segment       379..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacact cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcagcagaa accggggaaa gcccctgagc tcctgatcta
      241 ttatgcaaac cgtttggaaa ctggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgaggac tttgcaactt attactgtca
      361 acagtataat actttaccgc tcactttcgg cggagggacc aaggtggagg tcagacgag
//
LOCUS       KCVT01004299             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:24994:13523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004299
VERSION     KCVT01004299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24994:13523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81824.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          117 g          110 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggttagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004300             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:9288:9825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004300
VERSION     KCVT01004300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:9288:9825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81825.1"
                     /translation="CQQYDSFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          115 c           99 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaactggt atcagcagaa accggggaaa gcccctaaac tcctgatcta
      241 ttatacaaat cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtatgat agttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01004301             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15638:10421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004301
VERSION     KCVT01004301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15638:10421"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81826.1"
                     /translation="CLQGDTAPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gcaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattaacga ttatttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca gcttattact
      361 gtctacaggg tgatactgcc ccgttcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004302             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16445:9587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004302
VERSION     KCVT01004302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16445:9587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81827.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attccctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004303             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15949:4958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004303
VERSION     KCVT01004303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15949:4958"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..390
                     /gene="IGKV1-61"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81828.1"
                     /translation="CQQGQTYPLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          105 a          126 c          117 g           98 t
ORIGIN      
        1 acatggggag gctggtcaca ccctgtgcag gagtcagtct cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tccttgggct cctgctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacgcagt ctccatcctc cctgtccgca tctgtaggag acacagtcac
      181 catcacgtgc caggcgagtc aaggcattga caataattta aattggtatc aactgaaacc
      241 agggaaagcc cctaaactcc tgatcgacag ggcatccagt ttgcaaagtg ggattccctc
      301 tcggttcagt ggcagaggat ctgggacgga tttcgctctc accatcacca gcctgcagcc
      361 tgaggatttt gccacttatt tttgtcaaca aggtcagact tacccgctca ctttcggcgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01004304             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5567:18766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004304
VERSION     KCVT01004304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5567:18766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81829.1"
                     /translation="CQQYNDVLFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          128 c          115 g           93 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggatccca gataccgccg cagaaattgt
      121 aatgacgcag tctccagcca ccctgtcttt gtctccagga gaaacagcca ccctctcctg
      181 ccgggccagt gagagtgttg ccaactactt agcctggtac cagcagaaac ctggccaggc
      241 tcccaggctc cttatccatg gtgcatattt cagggccgct ggcatcccag acaggttcag
      301 tggcagcggg tctaggacag agttcactct caccattagc agcctggagc ctgaagatgt
      361 tggagtttat cactgtcagc agtataatga cgtgctattc actttcggcc ccgggacgaa
      421 actggacatc aaacgag
//
LOCUS       KCVT01004305             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:3733:8783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004305
VERSION     KCVT01004305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3733:8783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81830.1"
                     /translation="CMQYRHIPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          100 a          120 c          114 g          111 t
ORIGIN      
        1 acatgggtga ctgatcacga ctcctcaggt caccttctca caatgaagct ccctgctcag
       61 ctcctggggc tgctaatgct ctggctctct ggttccagtg gggatgttgt gatgacccag
      121 actccattct ccctgtccgt tagccctgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tgaatagtga agacggaaac acctatttgg attggtacct gcagaggccg
      241 ggccagtctc cacagccctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaattaacag agtggaggct
      361 gaggatgttg ggatttatat ctgcatgcaa tatagacaca ttccattcac tttcggcccc
      421 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01004306             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11250:9362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004306
VERSION     KCVT01004306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11250:9362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..374
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81831.1"
                     /translation="CQQDFDWPPPF"
     J_segment       379..411
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           98 a          123 c          106 g           87 t
ORIGIN      
        1 acatggggag ttaggaccca gagggaacca tggaagctcc agcacagctt ctcttcctcc
       61 tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct ccagccaccc
      121 tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag agtgttggca
      181 acaccttaac ctggtaccag cacaaacctg ggcaggctcc caaactcctc ctctatggtg
      241 catccaccag ggccaccggc atcccagaca ggttcaatgc cagtgggtct ggaacagagt
      301 tttctctcac catcagcagc ctggagcctg aagatgttgg aatttattat tgtcagcagg
      361 attttgactg gcctccgccg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004307             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13378:14552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004307
VERSION     KCVT01004307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13378:14552"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81832.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004308             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23072:4652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004308
VERSION     KCVT01004308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23072:4652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81833.1"
                     /translation="CQQHDNMPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          114 c          113 g           86 t
ORIGIN      
        1 acatggggag tcgcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tagggcatgg aatctggaaa caggggtccc atcaaggttc agtggaagtg gatccgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat aatatgccgc tcactttcgg tggagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01004309             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10294:19061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004309
VERSION     KCVT01004309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10294:19061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81834.1"
                     /translation="CMQALQTPRTF"
     J_segment       400..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          119 c          114 g          103 t
ORIGIN      
        1 acatgggaga tcagaactgc tcagttcacc ttctcaagat gaagttccat gctcagctcc
       61 tgggactgtt aatgctctgg gtctctgaat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gcccgtgacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctaca tagtaatgga aacacctatt tgtattggta cctgcagaag ccagggcagc
      241 ctcctcggct cctaatctat agagtttcca cccggttctc tggagtgcca gacaggttca
      301 gtggcagtgg atcaggcaca gacttcacac tgaaaatcag ccgcgtggag gctgaggatg
      361 tcggggttta ttactgcatg caagctttac agactcctcg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01004310             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18503:4426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004310
VERSION     KCVT01004310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18503:4426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81835.1"
                     /translation="CMQSLEFPWTF"
     J_segment       402..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           91 a          117 c          124 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttgtttctgc atgcaaagtc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaagcga g
//
LOCUS       KCVT01004311             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6682:10517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004311
VERSION     KCVT01004311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6682:10517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81836.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          125 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccgca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004312             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:23377:15034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004312
VERSION     KCVT01004312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23377:15034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81837.1"
                     /translation="CQQGYSYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          118 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agtatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgcaggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattggca atactttaaa ttggtatcaa cagaaaccgg ggaaagcccc tacactcctg
      241 atctataggg catccggttt gcaaagtggg actccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta tccgtacagt tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004313             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:7340:10529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004313
VERSION     KCVT01004313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7340:10529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..414
                     /note="immunoglobulin light chain variable region"
     V_region        101..414
     V_segment       101..379
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81838.1"
                     /translation="CQQGHSYPWTF"
     J_segment       385..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>425
                     /gene="IGKC"
BASE COUNT           99 a          117 c          113 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgtaggaga cacagtcacg atcacttgcc agtcgagtct
      181 aggcattggc aaatttttaa attggtatca gcagaaacca gggaaagccc ccaaactcct
      241 gatctatagg gcatccagtt tgcaaactgg gattccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcagcag cctgcagcct gaagattttg ccgcttatta
      361 ctgtcaacag ggtcatagtt acccgtggac gttcggccaa gggaccaagg tggagatgaa
      421 acgag
//
LOCUS       KCVT01004314             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7857:18574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004314
VERSION     KCVT01004314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7857:18574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81839.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          126 c          117 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaacggga catcaaacga g
//
LOCUS       KCVT01004315             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12752:11806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004315
VERSION     KCVT01004315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12752:11806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81840.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01004316             541 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7441:13931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004316
VERSION     KCVT01004316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 541)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7441:13931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    217..538
                     /note="immunoglobulin light chain variable region"
     V_region        217..538
     V_segment       217..500
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <478..>510
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81841.1"
                     /translation="CQQYNSLPLTF"
     J_segment       501..538
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        539..>541
                     /gene="IGKC"
BASE COUNT          136 a          130 c          136 g          139 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtaagga aggagacact agcagtttac ttagctcagt
      121 gtgctcacta ctgctgtgct attccgggaa agtctgctgc aacatgatta attgtgtgga
      181 catttatttt tgtttccaat ttcaggtgcc agatgtgaca ttcagatgac ccagtctcca
      241 tcctccctgt ctgcatctct gggggacaga gtcaccatca cttgccgggc aagtcaggac
      301 attagcagat atttaaattg gtatcagcag aaaccgggga aagcccctaa gttcctgatc
      361 tattatgtaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      421 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattattgt
      481 caacagtata atagtttacc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      541 g
//
LOCUS       KCVT01004317             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12356:17371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004317
VERSION     KCVT01004317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12356:17371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81842.1"
                     /translation="CQQYNSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          115 c          113 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatcg gcaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattagcag ttatttagcg tggtatcggc agaggccagg gaaagccccg gagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004318             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9029:3562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004318
VERSION     KCVT01004318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9029:3562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81843.1"
                     /translation="CQQYNTLPFTF"
     J_segment       307..344
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           91 a           93 c           79 g           84 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgagattca gatgacccag tctccatcct ccctgtctgc
       61 ctctgtcgga gacagagtca ccatcacttg ccgggcaagt caggacatta gcaattattt
      121 aaattggtat cagcagagac cggggaaagc ccctaaactc ctgatctatt atgcatcccg
      181 tttggagaat ggggtcccat caaagttcag cggcagtgga tctgggacag aattcagtct
      241 caccatcagt agcctgcaac ctgaagattt tgcagcttat tactgtcagc agtataatac
      301 cttaccattc actttcggcc ccgggaccaa actggaaatc aaacgag
//
LOCUS       KCVT01004319             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11450:6903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004319
VERSION     KCVT01004319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11450:6903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81844.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcacc cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004320             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11821:13243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004320
VERSION     KCVT01004320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11821:13243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81845.1"
                     /translation="CQQGHNTPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          115 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgtatg tgtaggagac aaagtcacca tcactttccg agccagtcag
      181 ggtattagca gctggttagc ctggtatcag cagaaaccag gggaagcccc taagctcctg
      241 atctataagg cgtccagtct ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagtctg aagattttgc aacttattat
      361 tgtcaacagg gtcacaatac cccgtacagt tttggccagg ggaccaaagt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01004321             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16521:9681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004321
VERSION     KCVT01004321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16521:9681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..372
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81846.1"
                     /translation="CQQGYSYPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           98 a          118 c          107 g           95 t
ORIGIN      
        1 acatgggggt ctcagtcagg acacagcatg gacatgaggg tccccgctca gctccttggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgacgca gtctccatcc
      121 tccctgtccg catctgcagg agacacagtc accatcactt gccaggcgag tcaaggcatt
      181 ggcaatactt taaattggta tcaacagaaa ccggggaaag cccctacact cctgatctat
      241 agggcatccg gtttgcaaag tgggactccc tctcggttca gcggcagtgg atctgggacg
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgccactta ttactgtcaa
      361 cagggttata gttatccgta cagttttggc caggggacca aactggagat caaacgag
//
LOCUS       KCVT01004322             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4644:13929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004322
VERSION     KCVT01004322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4644:13929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81847.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           86 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtctatttt
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004323             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18318:12310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004323
VERSION     KCVT01004323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18318:12310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81848.1"
                     /translation="CQQYNSGPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          118 c          102 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag ccaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgc cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtgg cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01004324             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15812:7061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004324
VERSION     KCVT01004324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15812:7061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..436
                     /note="immunoglobulin light chain variable region"
     V_region        101..436
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81849.1"
                     /translation="CMQALEFPRTF"
     J_segment       405..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>443
                     /gene="IGKC"
BASE COUNT           95 a          123 c          120 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgt atccagtggt gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgcgg atggaaacac ctatttggac tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ctccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtggctcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 agatgttggg atttattact gcatgcaagc tctagagttt cctcggacgt tcggccaggg
      421 gaccaaggtg gaaatcgaac gag
//
LOCUS       KCVT01004325             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5033:15996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004325
VERSION     KCVT01004325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5033:15996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81850.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004326             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7509:9168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004326
VERSION     KCVT01004326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7509:9168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81851.1"
                     /translation="CQQYNSLPFTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          104 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagctgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcgagacat
      181 tatcagttat ttaaattggt tccggcagaa accggggaaa gcccctcaac tcctgatctt
      241 ttatacagac cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctcca acctgaagat cttgcaaatt attactgtca
      361 acagtataat agtttaccct tcactttcgg cggagggacc aaggtggaga tcaaaggag
//
LOCUS       KCVT01004327             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:5865:4952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004327
VERSION     KCVT01004327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:5865:4952"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..364
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81852.1"
                     /translation="CQQHDDSPRTF"
     J_segment       366..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          104 a          112 c          103 g           85 t
ORIGIN      
        1 acatggggac agcatggaca cgagggtccc cgctcagctc ctggggctcc tgttgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtcacca tcacttgcac agccagtcag ggtattaata actggttggc
      181 ctggtatcaa cagaaaccag gaaaagcccc taaactcctg atctataggg catccaattt
      241 ggaaacaggg gtcccatcga ggttcggtgg aagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagatatcgc aacatattac tgtcaacagc atgatgattc
      361 ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004328             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13086:15322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004328
VERSION     KCVT01004328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13086:15322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81853.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          112 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004329             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8166:14494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004329
VERSION     KCVT01004329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8166:14494"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81854.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          107 c          110 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgtatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttttttaaa ttggtatcag cagaaaccgg ggaaagcccc taaggtcctg
      241 atctattatg caaaccgttt ggaaagaggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagtagc ctgcaacctg aggattttgc aacttattac
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004330             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:21623:19348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004330
VERSION     KCVT01004330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21623:19348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81855.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccagacc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004331             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22569:7057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004331
VERSION     KCVT01004331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22569:7057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81856.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 ccccttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004332             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:26244:8694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004332
VERSION     KCVT01004332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26244:8694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81857.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          123 c          116 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tgaaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cattcacttt cggccccggg
      421 accaagctgg aaatcaaacg ag
//
LOCUS       KCVT01004333             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15937:13896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004333
VERSION     KCVT01004333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15937:13896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81858.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcttccct gtctacatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01004334             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11029:9916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004334
VERSION     KCVT01004334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11029:9916"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81859.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          111 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 tatcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acgttaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004335             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:12988:13281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004335
VERSION     KCVT01004335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12988:13281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81860.1"
                     /translation="CIQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atacaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004336             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19122:7652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004336
VERSION     KCVT01004336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19122:7652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81861.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          125 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tgttgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gcccttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004337             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:7577:7118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004337
VERSION     KCVT01004337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7577:7118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81862.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          114 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac accgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004338             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:5546:10570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004338
VERSION     KCVT01004338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5546:10570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81863.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          110 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctcg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct ataggagaca gagtcaccat cacttgccgg gcaagtcggg
      181 acattagcag ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tcttttatgg aaaccgtttg gaaactgggg tcccatcaag gttcagcggc agtggatatg
      301 ggacagaatt cagtctcgcc atcagcagcc tgcaacctga agattttgct acttattact
      361 gtcaacagta taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004339             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9908:12900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004339
VERSION     KCVT01004339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9908:12900"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81864.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          111 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc atcacaaacc tgggcaggct cccaagctcc
      241 tcctctttgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004340             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19954:9388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004340
VERSION     KCVT01004340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19954:9388"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..448
                     /note="immunoglobulin light chain variable region"
     V_region        109..448
     V_segment       109..411
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <388..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81865.1"
                     /translation="CMQALEFPLTF"
     J_segment       412..448
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>451
                     /gene="IGKC"
BASE COUNT           94 a          123 c          124 g          110 t
ORIGIN      
        1 acatgggttg ccttgactga tcacgactcc tcaggtcacc ttctcacaat gaggctccct
       61 gctcagctcc tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg
      121 acccagactc cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg
      181 tctagtcaga gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag
      241 aagccaggcc agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc
      301 cccgacaggt tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg
      361 gaggctgagg atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc
      421 ggcggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004341             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6047:15264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004341
VERSION     KCVT01004341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6047:15264"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..387
                     /note="immunoglobulin light chain variable region"
     V_region        66..387
     V_segment       66..348
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <327..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81866.1"
                     /translation="CQQGYSFPFTF"
     J_segment       351..387
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>390
                     /gene="IGKC"
BASE COUNT           85 a          115 c           97 g           93 t
ORIGIN      
        1 acatggggag ggtccccgct cagctccttg ggctcctgct gctctggctc ccaggtgcca
       61 gatgtgacat ccagatgacg cagtctccat cctccctgtc cgcatctgta ggagacacag
      121 tcacgatcac ttgccaggcg agtcaaggca ttggcagtag tttaagctgg tatcagcaga
      181 aaccagggaa agcccctaac ctcctgatct ttagggcatc cagtttgcaa agtgggattc
      241 cctctcggtt cagcggcagt ggatctggga cggatttcac tctcaccatc agcagcctcc
      301 agcctgaaga ttttgccact tattactgtc aacagggtta tagtttcccc ttcactttcg
      361 gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01004342             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12235:7018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004342
VERSION     KCVT01004342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12235:7018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81867.1"
                     /translation="CQQYNSEPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          111 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtgga gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga gccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004343             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19838:8423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004343
VERSION     KCVT01004343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19838:8423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81868.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01004344             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22639:14622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004344
VERSION     KCVT01004344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22639:14622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..386
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81869.1"
                     /translation="CQHGYGIQLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          116 c          114 g           97 t
ORIGIN      
        1 acatgggggt aggagtcagt cccagtcagg acacagcatg gacatgaggg cccccactca
       61 gctcctgggg ttcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg catctgtggg agacagagtc accatctctt gccaggcgag
      181 tcaggacatt agcaatgatt tagcctggta tcagcagaaa ccgggaaaag cccctaggct
      241 cctgatgtat aaggcatccg ctttgcagat tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcaa cagcctgcag cctgaagatt ttgcaactta
      361 ctactgtcaa catggttatg gtatccagct cactttcggt ggagggacca aggtggacat
      421 caaacgag
//
LOCUS       KCVT01004345             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24664:19564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004345
VERSION     KCVT01004345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24664:19564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81870.1"
                     /translation="CLQDIQLPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           86 a          124 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattgtgat gactcagact
      121 ccactctccc tgtccgtcgc ccctggagag ccggcctcca tctcctgcag gtctagccag
      181 agcctcctgc ataggaatgg atacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacagc tcctgatcta tttgggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgcaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgctt acaagatata cagcttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01004346             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6008:12163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004346
VERSION     KCVT01004346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6008:12163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..376
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81871.1"
                     /translation="CQQVYSPAFSF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          118 c          106 g          103 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ctgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gatatccaga tgacccagtc
      121 tccatctgcc ttgtctgcat ctgtaggaga cagagtcacc atctcttgcc gggcaagtca
      181 gaacatttat agttatttag cgtggtatca gcagaatcca gggaaagccc ctaagctcct
      241 gatctatgct acatccagac tgcaaagtgg gattccctct cggttcagcg gcagtggatc
      301 tgggacagac ttcagtctca ccatcagtag cctgcagcct gaagattctg caacctatta
      361 ctgtcaacag gtttatagtc ctgcattctc tttcggcccc gggaccaaac tggacatcaa
      421 acgag
//
LOCUS       KCVT01004347             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8486:14247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004347
VERSION     KCVT01004347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8486:14247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81872.1"
                     /translation="CQQYDSDSLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          117 c          112 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      181 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01004348             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17956:15813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004348
VERSION     KCVT01004348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17956:15813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..322
                     /note="immunoglobulin light chain variable region"
     V_region        123..322
     V_segment       123..285
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81873.1"
                     /translation="CMQALEFPLTF"
     J_segment       286..322
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           70 a           87 c           90 g           78 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattctg atgacccaga
      121 ctccactctc cacagctctt gatttatgag gtttccaagc gggcctctgg agtccccgac
      181 aggttcagtg gcagtgggtc aggcactgat ttcacactga aaatcagcag agtggaggct
      241 gaggatgttg gggtttatca ctgcatgcaa gctctagagt ttcctctcac tttcggcgga
      301 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01004349             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11371:6579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004349
VERSION     KCVT01004349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11371:6579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81874.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          124 c          116 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagacacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagtc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004350             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18810:18355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004350
VERSION     KCVT01004350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18810:18355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..365
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <348..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81875.1"
                     /translation="CQQGYSYPYSF"
     J_segment       371..408
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>411
                     /gene="IGKC"
BASE COUNT           97 a          116 c          105 g           93 t
ORIGIN      
        1 acatggggtc aggacacagc atggacatga gggtccccgc tcagctcctt gggctcctgc
       61 tgctctggct cccaggtgcc agatgtgaca tccagatgac gcagtctcca tcctccctgt
      121 ccgcatctgc aggagacaca gtcaccatca cttgccaggc gagtcaaggc attggcaata
      181 ctttaaattg gtatcaacag aaaccgggga aagcccctac actcctgatc tatagggcat
      241 ccggtttgca aagtgggact ccctctcggt tcagcggcag tggatctggg acggatttca
      301 ctctcaccat cagcagcctg cagcctgaag attttgccac ttattactgt caacagggtt
      361 atagttatcc gtacagtttt ggccagggga ccaaactgga gatcaaacga g
//
LOCUS       KCVT01004351             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25970:10999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004351
VERSION     KCVT01004351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25970:10999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81876.1"
                     /translation="CMQALEFPYTF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctcctca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttacactttt ggccagggga
      421 ccacagtgga gatcaaacga g
//
LOCUS       KCVT01004352             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:10138:3112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004352
VERSION     KCVT01004352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10138:3112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81877.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggata tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004353             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17142:6444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004353
VERSION     KCVT01004353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17142:6444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..362
                     /note="immunoglobulin light chain variable region"
     V_region        82..362
     V_segment       82..322
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81878.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       330..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           97 a           89 c           91 g           88 t
ORIGIN      
        1 acatggggag aaccactcag gacacaggat ggacatgacg gtccccgctt atctcctggg
       61 gctccttctg ctctggctcc caggagacaa agtcaccatc acttgcaggg caagtcagga
      121 cattggtaat tatttaaatt ggtatcagca gaaaccagga aaagctccta aggtcctgat
      181 ctatggtgta tccaatttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagatctt actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      301 tcaaccgttt aaaagttacc tttcggtccc tttcggcgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01004354             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:8345:15670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004354
VERSION     KCVT01004354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8345:15670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81879.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          109 c          106 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct ccttctgtcg gagacagagt caccatcact tgccgggcaa gtcaggtcat
      181 taggagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagac tttggaactt attactgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004355             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22272:8069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004355
VERSION     KCVT01004355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22272:8069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81880.1"
                     /translation="CMQALDFPYSF"
     J_segment       276..312
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           80 c           86 g           80 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagtctc
      121 cacagctctt gatttttgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactaat ttcacactga aaatcagcag tgtggaggct gaggatgttg
      241 gggtctatta ctgcatgcaa gctctagact ttccttacag ttttggccag gggaccacag
      301 tggagattaa acgag
//
LOCUS       KCVT01004356             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9737:15194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004356
VERSION     KCVT01004356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9737:15194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81881.1"
                     /translation="CQQYTSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          120 c          104 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtgaggacgt
      181 tagcagtcat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctaatcta
      241 ttttgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgaggac tttgcaactt atcactgtca
      361 acagtacact agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01004357             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10451:15741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004357
VERSION     KCVT01004357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10451:15741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81882.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          125 c          111 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc aacagcttag cctggtacca acaaaaacct gggcagcctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagag gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004358             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24692:19696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004358
VERSION     KCVT01004358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24692:19696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81883.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004359             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8939:4064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004359
VERSION     KCVT01004359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8939:4064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81884.1"
                     /translation="CQQHDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aagattcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaatctatt
      361 actgtcaaca gcatgacagt gatccgttca ctttcggtgg ggggaccaag gtagacatca
      421 aacgag
//
LOCUS       KCVT01004360             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9335:12075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004360
VERSION     KCVT01004360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9335:12075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81885.1"
                     /translation="CQQYNSLPYIF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          111 c          107 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gtttttttaa attggtatca gcagaaaccg gggaaagccc ctaaacccct
      241 gatctattat gcaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ctgtcaacag tataatagtt taccgtacat ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004361             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10421:14307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004361
VERSION     KCVT01004361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10421:14307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81886.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ttgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004362             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22868:13434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004362
VERSION     KCVT01004362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22868:13434"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..282
                     /note="immunoglobulin light chain variable region"
     V_region        6..282
     V_segment       6..235
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81887.1"
                     /translation="CQQHNGYPPTF"
     J_segment       248..282
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>285
                     /gene="IGKC"
BASE COUNT           82 a           72 c           70 g           61 t
ORIGIN      
        1 acatgggaga cacagtcacc atcacttgtc gggcaagtca ggacattacg aatgatttag
       61 cctggtatca acagaaacca ggtaaagccc cgaagcccct gatctattac gcatccaatt
      121 tggagagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagat ttcactctca
      181 ccatcagcag cctgcagcct gaagattttg caacttatta ttgtcaacag cataatggat
      241 accctccgac gttcggccaa gggaccaggg tggaaatcaa acgag
//
LOCUS       KCVT01004363             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11696:12724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004363
VERSION     KCVT01004363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11696:12724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..307
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81888.1"
                     /translation="CQQGDSYPRTF"
     J_segment       309..344
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           91 a           88 c           88 g           80 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgtcccag tctccttcct ccctgtctgc
       61 atctgtggga gacagagtca ccatcacttg ccgggcaagt caggacatta gagattattt
      121 aaattggtat cagcagcaac cggggaaagc ccctaaactc ctgatgtatt atgcaaacag
      181 tctggcaagt ggagtcccat caaggttcag cggcagtgga tctgggacag aattcagtct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agggtgacag
      301 ttatcctcgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01004364             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:28493:10203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004364
VERSION     KCVT01004364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:28493:10203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81889.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           98 a          122 c          111 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgctg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga tacacctatt tgcattggta tttgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tggaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01004365             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14331:6221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004365
VERSION     KCVT01004365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14331:6221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81890.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004366             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14568:17437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004366
VERSION     KCVT01004366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14568:17437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81891.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          125 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004367             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16790:7748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004367
VERSION     KCVT01004367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16790:7748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..275
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81892.1"
                     /translation="CLQFKTFPYSF"
     J_segment       276..313
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           75 a           83 c           76 g           82 t
ORIGIN      
        1 acatgggagt ctccatcttc cctgtctgca tctgtaggag acactgtcac catctcttgc
       61 cgggcaagtc agggtattag cagttcttta agttggtttc agcagaaacc agggaaagcc
      121 cctaagctcc tcatctatgc tgcatccact ttggccggtg gggtcccatc aaggttcagc
      181 ggcagtggat ctgggacaga cttcactctc accatcagca gcctgcagcc tgaagatttt
      241 gcaacttatt actgtctaca gtttaaaact ttcccgtaca gttttggcca ggggaccaaa
      301 gtggagatca aacgag
//
LOCUS       KCVT01004368             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18117:13772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004368
VERSION     KCVT01004368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18117:13772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..407
                     /note="immunoglobulin light chain variable region"
     V_region        102..407
     V_segment       102..370
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81893.1"
                     /translation="CQQNSNWPLTF"
     J_segment       371..407
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>410
                     /gene="IGKC"
BASE COUNT           99 a          118 c          111 g           82 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcaga aacctgggca ggctcccaga ctcctcatct atggtgcatc
      241 caacagggcc actggcatcc cagacaggtt cagtggcagt gggtctggga cagagttcac
      301 tctcaccatc agcagcctgg agcctgaaga tgttgcactt tattattgtc agcagaatag
      361 taactggcct ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004369             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14759:13718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004369
VERSION     KCVT01004369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14759:13718"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..241
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81894.1"
                     /translation="CQQYNSEPRTF"
     J_segment       249..283
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           76 a           70 c           79 g           61 t
ORIGIN      
        1 acatggggag acagagtcac catcacttgt cgggcgagtc agggcattcg cagttattta
       61 gcgtggtatc agcagaaacc agggaaaccc ccgaagccct tgatctatta cgcgtccact
      121 ttggaaagtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga attcactctc
      181 accatcagca gcctgcagcc tgaagatttt gcaacttatt actgtcaaca gtataacagt
      241 gagccgcgca ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01004370             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16048:4349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004370
VERSION     KCVT01004370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16048:4349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81895.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgt cggtctagtc
      181 agagcctctt ggctagtgag gatggaaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acaactcttg atttatgaag tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa gatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tccgctcact ttcggcggcg
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004371             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:9835:17166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004371
VERSION     KCVT01004371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9835:17166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81896.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgtt aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004372             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7829:13609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004372
VERSION     KCVT01004372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7829:13609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81897.1"
                     /translation="CMQGTQLLTF"
     J_segment       392..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          101 a          118 c          114 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acaaccggcc tccatctcct gcaggtctag tcaaagcctt
      181 ctacacactg atgggaaaac ctacttgaat tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatcaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggagactga ggatgttgga
      361 gtttattact gcatgcaagg tacacagctt ctcactttcg gtggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01004373             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9261:15971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004373
VERSION     KCVT01004373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9261:15971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..373
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81898.1"
                     /translation="CQQYYSFPITF"
     J_segment       387..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT          100 a          113 c          114 g           98 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggatcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattaac acctggttaa tttggtatca gcagaaacca gggaaagccc ctaaggccct
      241 gatctataag gcatccagtt tgcaaggtgg ggtcccttcc aggttcagcg gcagtggatc
      301 tggggcagac ttcactctca ccatcaccaa cctgcagcct gaagattttg gaatttatta
      361 ctgtcaacaa tattatagtt ttccgatcac tttcggtggg gggaccaagg tggagatcag
      421 gcgag
//
LOCUS       KCVT01004374             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:8860:7653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004374
VERSION     KCVT01004374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8860:7653"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81899.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           91 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004375             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:4697:8699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004375
VERSION     KCVT01004375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4697:8699"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81900.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccacacggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggagactgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004376             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13486:8722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004376
VERSION     KCVT01004376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13486:8722"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81901.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc acttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tgcagatcaa
      421 acgag
//
LOCUS       KCVT01004377             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23926:2835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004377
VERSION     KCVT01004377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23926:2835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81902.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004378             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7763:12206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004378
VERSION     KCVT01004378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7763:12206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81903.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          123 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004379             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10307:14102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004379
VERSION     KCVT01004379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10307:14102"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81904.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc atggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004380             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21811:6826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004380
VERSION     KCVT01004380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21811:6826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81905.1"
                     /translation="CMQALDFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          116 c          124 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatct agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgtaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccagggcag
      241 tctccacaac tcttgattta tgaggtttcc gaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctctg gactttccgt ggacgttcgg ccaagggacc
      421 aaggtggaag tcaaacgag
//
LOCUS       KCVT01004381             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15095:18068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004381
VERSION     KCVT01004381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15095:18068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81906.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagctac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004382             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17873:3919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004382
VERSION     KCVT01004382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17873:3919"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81907.1"
                     /translation="CQQDNSIPITF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          112 c          103 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccattact tgccgggcaa gtcagggcat
      181 tagtaattat ttaaattggt atcagcagaa accggggaaa gccccaaagg tcctgatcta
      241 ttatgtagac agtttgtcaa gtggggtccc atcaaggttc accggcagcg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgctactt attactgtca
      361 acaggataat agtattccaa tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01004383             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9127:13901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004383
VERSION     KCVT01004383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9127:13901"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81908.1"
                     /translation="CMQPREFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc gagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga catcaaacga g
//
LOCUS       KCVT01004384             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22048:14589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004384
VERSION     KCVT01004384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22048:14589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81909.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004385             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18900:13396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004385
VERSION     KCVT01004385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18900:13396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81910.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          102 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga tgattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01004386             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17603:17807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004386
VERSION     KCVT01004386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17603:17807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..415
                     /note="immunoglobulin light chain variable region"
     V_region        96..415
     V_segment       96..374
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81911.1"
                     /translation="CQQSYRYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>420
                     /gene="IGKC"
BASE COUNT          101 a          116 c          107 g           96 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgagaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agcccctaaa ctcctgatgt
      241 atcttgcatc cactttgcag agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcgccatc agcagcctgc agcctgaaga tgctgcaact tattactgtc
      361 agcagagtta tcgttatccg ctcactttcg gtggagggac ccaggtggaa atcaatcgag
//
LOCUS       KCVT01004387             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19084:11506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004387
VERSION     KCVT01004387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19084:11506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81912.1"
                     /translation="CQQYNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          109 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gtataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004388             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:13355:15788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004388
VERSION     KCVT01004388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13355:15788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81913.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaagcga g
//
LOCUS       KCVT01004389             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20380:18104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004389
VERSION     KCVT01004389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20380:18104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81914.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggggagt cggcctccat ctcctgcagg tctagccaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004390             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:7233:6550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004390
VERSION     KCVT01004390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7233:6550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81915.1"
                     /translation="CQQYNSDPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          112 c          111 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccaggtgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttagaagtta tttagcgtgg tatcagctga gaccagggaa agccccgaag gccttaatct
      241 attacgcgac cattttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgagga ttttgcaact tatttctgtc
      361 aacagtataa cagtgacccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004391             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16744:13974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004391
VERSION     KCVT01004391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16744:13974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81916.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          112 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004392             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12969:7818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004392
VERSION     KCVT01004392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12969:7818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81917.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          125 c          114 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcaacagct tagcctggta ccaacaaaaa cctgggcagc ctcccaggct
      241 cctcatctat ggtgcatcca gcagggccac tggcatccca gacaggttca gaggcagtgg
      301 gtctgggaca gacttcactc tcaccatcac cagcctggag cctgaagatg ttgcagttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01004393             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19892:5309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004393
VERSION     KCVT01004393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19892:5309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81918.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          120 c          106 g           91 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagcat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004394             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:5674:9363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004394
VERSION     KCVT01004394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5674:9363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81919.1"
                     /translation="CQQYNTLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          113 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cgttcagatg acccagtctc
      121 catcctacct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacgt ttatttaaat tggtatcacc agaaaccggg gaaagcccct aacctcctga
      241 tctattatgc aaaccgtttg gaaaatgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgcg acttattact
      361 gtcaacagta taatacttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004395             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9352:19957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004395
VERSION     KCVT01004395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9352:19957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81920.1"
                     /translation="CQQYNSDWRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          115 c          113 g           92 t
ORIGIN      
        1 acatggggag agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg actggcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004396             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:7316:8276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004396
VERSION     KCVT01004396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7316:8276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81921.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          121 c          120 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cggtggggac attgtgatga cccaggctcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaactct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004397             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10425:6676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004397
VERSION     KCVT01004397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10425:6676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81922.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          127 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agcgaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004398             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22825:11072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004398
VERSION     KCVT01004398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22825:11072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81923.1"
                     /translation="CLQGDTAPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggcaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcattaac gattatttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg acagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggtgatactg ccccgttcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004399             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:23011:8165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004399
VERSION     KCVT01004399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23011:8165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81924.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          127 c          109 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc aacacaaacc tgggcaggct cccaaactcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004400             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:4462:16147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004400
VERSION     KCVT01004400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:4462:16147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81925.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          126 c          112 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca atggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004401             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11509:3689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004401
VERSION     KCVT01004401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11509:3689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81926.1"
                     /translation="CIQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cattcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004402             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16459:18253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004402
VERSION     KCVT01004402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16459:18253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81927.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          110 g           95 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctaatcta
      241 tgctgcatct agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagttt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004403             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7699:4997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004403
VERSION     KCVT01004403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7699:4997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81928.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          114 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaaccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004404             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18522:11136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004404
VERSION     KCVT01004404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18522:11136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..409
                     /note="immunoglobulin light chain variable region"
     V_region        126..409
     V_segment       126..372
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81929.1"
                     /translation="CMQGLEFPRTF"
     J_segment       374..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           94 a          109 c          110 g           99 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtggtg acattgtgat gacccagact
      121 ccactctcca tctcctgcag atctagtcag agtctcttgg atagtgcgga tggaaacacc
      181 tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtc
      241 tccgaccggg cctctggagt cccacacagg ttcactggca gtggctcaga cactgatttc
      301 acactaaaga tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaaggt
      361 ctagagtttc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004405             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:24111:15312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004405
VERSION     KCVT01004405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24111:15312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81930.1"
                     /translation="CMQALEFPYTF"
     J_segment       399..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          106 t
ORIGIN      
        1 acatggggga cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc cagagtccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagaccc
      181 tcttggatag tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt
      241 ctcctcaact cttgatttat gaggtttcct accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcaa cagagtggag gctgaggatg
      361 ttggggttta ttactgcatg caagctctag agtttcctta cacttttggc caggggacca
      421 cagtggagat caaacgag
//
LOCUS       KCVT01004406             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20360:14867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004406
VERSION     KCVT01004406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20360:14867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81931.1"
                     /translation="CYQYTGGYTF"
     J_segment       382..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           95 a          128 c          110 g           85 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagag ggaaccatgg aagccccagc tcggcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaag ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccactctct cctgcagggc cagtcagagt
      181 gttagcaact acttagcctg gtaccagcag aaacctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccagcagggc cactggcatc ccagacagat tcagtggcag cgggtctggg
      301 acagagttca ccctcaccat cagcggccta gagcctgaag atgttggagt ttatcactgc
      361 tatcagtata ccggcggata cactttcggc cccgggacca aactggagat caaacgag
//
LOCUS       KCVT01004407             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19049:13506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004407
VERSION     KCVT01004407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19049:13506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81932.1"
                     /translation="CMQGTHLPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          119 c          115 g          100 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatctagt ggggatgttg tgatgactca gtctcccctc
      121 tccctgccca tcacccctgg acaaccggcc tccatctcct gcaggtctag ttacagcctt
      181 atacacagtg atgggacaac ctacttgaat tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatcaggt ttctaaccgg gactctgggg tcccagtcag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttgga
      361 gtttattact gcatgcaagg tacacacctt ccgtacagtt ttggccaggg gaccaaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01004408             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6366:10801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004408
VERSION     KCVT01004408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6366:10801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81933.1"
                     /translation="CQQGYTYPFTF"
     J_segment       386..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          122 c          106 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgctc ctgtaggaga cacagtcacg atcacttgcc aggcgagtca
      181 aggcattggc agaaatttaa attggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gctctatagg gcatccagtt tgcaaagtgg gattccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcagcag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatactt accctttcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01004409             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20878:12180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004409
VERSION     KCVT01004409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20878:12180"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81934.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          102 a          109 c          108 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatatct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagag accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004410             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23235:16214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004410
VERSION     KCVT01004410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23235:16214"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    17..294
                     /note="immunoglobulin light chain variable region"
     V_region        17..294
     V_segment       17..257
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <234..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81935.1"
                     /translation="CMQGLEFPWTF"
     J_segment       258..294
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>297
                     /gene="IGKC"
BASE COUNT           72 a           63 c           92 g           70 t
ORIGIN      
        1 acatggggga tcacgactcc tgcaggtcta gtcagagtct cttggatagt gaggttggag
       61 acacctattt ggagtggtac ctgcagaagc caggccagtc tccacagctc ttgatttatg
      121 aggtgtccaa ccgggcctct ggagtcccag acaggttcag tggcagtggg tcagacactg
      181 atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat tactgcatgc
      241 aaggtctaga gtttccttgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01004411             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16803:18358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004411
VERSION     KCVT01004411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16803:18358"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..286
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81936.1"
                     /translation="CQQYNSDPFTF"
     J_segment       287..324
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>327
                     /gene="IGKC"
BASE COUNT           88 a           86 c           78 g           75 t
ORIGIN      
        1 acatgggcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtaa
       61 ccatcacttg tcgggcgagt caggacataa gaagttattt agcgtggtat cagcagaaac
      121 caggcaaagc cccgaagccc ttgatctatt acgcatccgt tttggaaagt ggggtcccat
      181 caaggttcag tggcagtgga tctgggacag aattcactct caccatcagc agtctgcagc
      241 ctgaggattt tgcaacttat tactgtcaac agtataacag tgacccattc actttcggcc
      301 ccgggaccaa actggatacc aaacgag
//
LOCUS       KCVT01004412             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14628:10480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004412
VERSION     KCVT01004412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14628:10480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..405
                     /note="immunoglobulin light chain variable region"
     V_region        66..405
     V_segment       66..368
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <345..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81937.1"
                     /translation="CMQALEFPLTF"
     J_segment       369..405
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT           89 a          109 c          112 g           98 t
ORIGIN      
        1 acatggggag gctccctgct cagctcctgg gactgctaat gctctggctc cctggatcca
       61 ctggggacat tgtgctgacc cagactccac tctccctgcc cgtcaccctt ggagagccgg
      121 cctccatctc ctgcaggtct agtcagaacc tcttggatag tgaggatgga aacacctatt
      181 tggaatggta cctgcagaag ccaggccagt ctccacagct cttgatttat gaggtttcca
      241 atcgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact gatttcacac
      301 tgaaaatcag cagagtggag cctgaggatg ttggggttta ttactgcatg caagctctag
      361 aatttcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01004413             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22057:17441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004413
VERSION     KCVT01004413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22057:17441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81938.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          125 c          121 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01004414             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20018:18047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004414
VERSION     KCVT01004414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20018:18047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81939.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccagtttgg aaagtggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01004415             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21626:6712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004415
VERSION     KCVT01004415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21626:6712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81940.1"
                     /translation="CQQYNSLPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          109 c          107 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtta ttatttaaat tggtatcaac agaaaccggg gaaagcccct aaggtcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga gattttgcaa gttattactg
      361 tcaacaatat aatagtttac cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004416             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23829:5110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004416
VERSION     KCVT01004416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23829:5110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..377
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81941.1"
                     /translation="CYQHSRGWAF"
     J_segment       378..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT           98 a          121 c          114 g           83 t
ORIGIN      
        1 acatggggtg ctaggttagt acccagaagg aaccatggaa gccccagctc agcttctctg
       61 ccttctgcta ctctggctcc caggtaccac cggacaaatt atattgacac agtctccagc
      121 caccctgtct ttggcaccag gggaaagagc cactctctcc tgcagggcca gtgagaatgt
      181 tggcagctac ttagcctggt accagcagaa ccctgggcag gctcccaggc tcctcgtcca
      241 cagtgcgtcc agcagggcca ctaacatccc agacaggttc agtggcagtg ggtctcggac
      301 agagttcacc ctcaccatca gcagtctgga gcctgaagat gttggagtct attactgcta
      361 tcaacatagc agggggtggg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004417             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:24695:11808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004417
VERSION     KCVT01004417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24695:11808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81942.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 caaaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004418             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18013:3490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004418
VERSION     KCVT01004418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18013:3490"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81943.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccccggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004419             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:6840:14410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004419
VERSION     KCVT01004419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:6840:14410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..426
                     /note="immunoglobulin light chain variable region"
     V_region        90..426
     V_segment       90..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81944.1"
                     /translation="CMQGTHLPYSF"
     J_segment       389..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           97 a          118 c          117 g           97 t
ORIGIN      
        1 acatggggat caggactcct cagttcacca tgaggctccc tgctcagctc ctggggctgc
       61 tattgctctg cgtccccggg tccagtgggg atgttgtgat gactcagtct ccactctccc
      121 tgcccatcac ccctggacaa ccggcctcca tttcctgcag gtctagtcaa agccttgtac
      181 acagtgatgg gaatacctac ttgaattggt atcagcagaa gccaggccaa cctcccaggc
      241 gcctaattta tctggtttct aaccgggact ctggggtccc agacagattc agcggcagcg
      301 gggcagggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttggagttt
      361 attactgcat gcaaggaaca caccttccgt acagttttgg ccaggggacc gaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01004420             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17105:6305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004420
VERSION     KCVT01004420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17105:6305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81945.1"
                     /translation="CLQGYNIPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          110 c          112 g           98 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccagt tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gtgtccagtt tggaaggtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtctacag ggttataata tcccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004421             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19301:19948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004421
VERSION     KCVT01004421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19301:19948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81946.1"
                     /translation="CTQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc acgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004422             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18543:15346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004422
VERSION     KCVT01004422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18543:15346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..258
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <236..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81947.1"
                     /translation="CLQSKNSPWSF"
     J_segment       259..296
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>299
                     /gene="IGKC"
BASE COUNT           83 a           74 c           80 g           62 t
ORIGIN      
        1 acatgggggg cagagggcca ccatcacctg cagagccagt gagagtgtca gtgcctttgg
       61 aataagcctc attcactggt atcaacagaa accaggacaa cctcctaaac tcctgattta
      121 ccaagcaatc aataaggaga ctggggtccc agccaggttc agcggcagtg ggtctgggac
      181 cgatttcacc ctcacaatta atcctgtgga acctgacgat ggtgcagatt attactgtct
      241 gcagagtaag aattctccgt ggtcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004423             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17617:13784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004423
VERSION     KCVT01004423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17617:13784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81948.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgcta ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004424             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15182:10159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004424
VERSION     KCVT01004424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15182:10159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81949.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          118 c          108 g           90 t
ORIGIN      
        1 acatggggag agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatgtattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004425             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11268:3498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004425
VERSION     KCVT01004425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11268:3498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81950.1"
                     /translation="CMQSLDIPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagcctggcc
      241 agtctccaca gcttttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagacattcc gtggacgttc ggcccaggga
      421 ccaaggtgga aatcaaagga g
//
LOCUS       KCVT01004426             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:25738:15202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004426
VERSION     KCVT01004426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25738:15202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    163..308
                     /note="immunoglobulin light chain variable region"
     V_region        163..308
     V_segment       163..272
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81951.1"
                     /translation="CMQSLDFPLTF"
     J_segment       273..308
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>313
                     /gene="IGKC"
BASE COUNT           66 a           88 c           85 g           74 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctccagacag gttcagtggc
      181 agtgggtcag acacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      241 gtttattact gcatgcagtc tctagatttt ccgctcacct tcggtggagg gaccaaggtg
      301 gagatcaatc gag
//
LOCUS       KCVT01004427             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12454:15357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004427
VERSION     KCVT01004427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12454:15357"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..253
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81952.1"
                     /translation="CQQYDSDPFTF"
     J_segment       256..291
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>294
                     /gene="IGKC"
BASE COUNT           77 a           70 c           81 g           66 t
ORIGIN      
        1 acatgggatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca
       61 gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg
      121 cgtccacttt ggaaagtggg gtcccgtcaa ggttcagcgg cagtggatct gggacagaat
      181 tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt
      241 atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa cgag
//
LOCUS       KCVT01004428             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14075:10530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004428
VERSION     KCVT01004428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14075:10530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..394
                     /note="immunoglobulin light chain variable region"
     V_region        58..394
     V_segment       58..356
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81953.1"
                     /translation="CMQSIKDPFTF"
     J_segment       357..394
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           93 a          108 c          101 g           95 t
ORIGIN      
        1 acatgggctg ctcagctcct cgggctgttg atgctctggg tccctggatc cagtggggat
       61 attgtgatga cccagacccc actctcggtg cccgtcaccc ctggagagcc ggcctccatc
      121 tcctgcaggt ctagtcaaag ccttctccat agtaatggag acacctattt acattggtac
      181 cttcagaggt caggccagtc tccacggctc ctgatctata aagtaaccaa tcggctacct
      241 ggggtcccag acaggttcag tggcagtggg tcaggcacag atttcacact gaaaatcagc
      301 agggtggagc ctgaggatat tggtgtttat ttctgcatgc aaagtataaa agatccattc
      361 actttcggcc ccgggaccaa actggatatc aaacaag
//
LOCUS       KCVT01004429             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5839:11488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004429
VERSION     KCVT01004429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5839:11488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81954.1"
                     /translation="CQQYNSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          112 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tagcagttat ttagcgtggt atcggcagag gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgactcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004430             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:6626:6033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004430
VERSION     KCVT01004430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6626:6033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81955.1"
                     /translation="CLQSKNSPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          102 a          114 c          115 g          100 t
ORIGIN      
        1 atggggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcgtc tgcagagcca gtgagagtgt
      181 caatgtcttt ggaataaacc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 acccctgatt taccaagcat ccaataaaga aactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgacg atgctgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggacgttt ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01004431             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8398:16913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004431
VERSION     KCVT01004431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8398:16913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81956.1"
                     /translation="CQQYNSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          113 c          106 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc agaaaccagg aaaagccccg aaggccttga
      241 tctattacgc atccatttta gaaagtgcgg taccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc ttcagtctga cgattttgca acttattact
      361 gtcaacagta taacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004432             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:14986:8574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004432
VERSION     KCVT01004432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14986:8574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81957.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004433             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:2274:15665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004433
VERSION     KCVT01004433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:2274:15665"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81958.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004434             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8735:10430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004434
VERSION     KCVT01004434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8735:10430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81959.1"
                     /translation="CIQGLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          118 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgacgat ggaaatacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcacac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atacaaggtc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004435             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11666:18997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004435
VERSION     KCVT01004435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11666:18997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81960.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          122 c          117 g           87 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca ccagcagctt agcctggtat cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01004436             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21207:22482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004436
VERSION     KCVT01004436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21207:22482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81961.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          123 c          120 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accggtcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01004437             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22016:16946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004437
VERSION     KCVT01004437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22016:16946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81962.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttggag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004438             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11165:15949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004438
VERSION     KCVT01004438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11165:15949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81963.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          117 c          108 g           86 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccaggtgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcaggata
      181 ttaacacctg gttggcctgg tatcaacaga agccagggaa agcccctaag gtcctgatct
      241 ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc aacagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004439             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13851:14774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004439
VERSION     KCVT01004439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13851:14774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81964.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          113 a          118 c          103 g           88 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcacga
      181 tattaacaac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aggtcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggttctgg
      301 gacagatttc actctcacca tcaacaacct gcagcctgaa gatatcgcaa catattactg
      361 tcaacaacat gatgattccc ctcggacctt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004440             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:6761:19704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004440
VERSION     KCVT01004440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6761:19704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81965.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          115 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004441             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12700:12101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004441
VERSION     KCVT01004441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12700:12101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81966.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcgag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004442             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16688:3002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004442
VERSION     KCVT01004442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16688:3002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81967.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aagtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01004443             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20196:8700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004443
VERSION     KCVT01004443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20196:8700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81968.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca ttgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004444             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20750:18093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004444
VERSION     KCVT01004444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20750:18093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..372
                     /note="immunoglobulin light chain variable region"
     V_region        90..372
     V_segment       90..334
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <312..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81969.1"
                     /translation="CMQALEFPWTF"
     J_segment       335..372
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>375
                     /gene="IGKC"
BASE COUNT           85 a           93 c          105 g           92 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccatgtcctg caggtctagt cagagtctct
      121 tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca ggccagtctc
      181 cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg
      241 gcggtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gatgatgttg
      301 gggtttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa gggaccaagg
      361 tggaaatcaa acgag
//
LOCUS       KCVT01004445             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20678:19933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004445
VERSION     KCVT01004445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20678:19933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..329
                     /note="immunoglobulin light chain variable region"
     V_region        8..329
     V_segment       8..291
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81970.1"
                     /translation="CMQDIQLPLTF"
     J_segment       292..329
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>332
                     /gene="IGKC"
BASE COUNT           74 a           93 c           89 g           76 t
ORIGIN      
        1 acatgggcag actccactct ccctgcccgt cacccctgga gagccggcct ccatctcctg
       61 caggtctagt cagagcctcc tgcatagtaa tggatacacc tatttgtttt ggtacctgca
      121 gaagccaggc cagtctccac aactcctgat ctacttgggt tccaaccggg cctctggagt
      181 cccagacagg ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagccgggt
      241 ggaggctgaa gatgttgggg tttattactg catgcaagat atacagcttc cgctcacttt
      301 cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004446             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11350:18327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004446
VERSION     KCVT01004446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11350:18327"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81971.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004447             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12872:7609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004447
VERSION     KCVT01004447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12872:7609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81972.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          114 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004448             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10947:9869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004448
VERSION     KCVT01004448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10947:9869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81973.1"
                     /translation="CMQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           90 a          124 c          121 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacaact cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaagatg
      361 ttggggttta ttactgcatg caagatatac agcttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01004449             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16224:8102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004449
VERSION     KCVT01004449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16224:8102"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81974.1"
                     /translation="CQQYNSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          114 c          105 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc agaaaccagg aaaagccccg aaggccttga
      241 tctattacgc atccatttta gaaagtgcgg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga cgattttgca acttattact
      361 gtcaacaata taacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004450             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11853:16436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004450
VERSION     KCVT01004450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11853:16436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81975.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagaac cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004451             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10516:12279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004451
VERSION     KCVT01004451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10516:12279"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81976.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004452             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:7966:9863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004452
VERSION     KCVT01004452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:7966:9863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..423
                     /note="immunoglobulin light chain variable region"
     V_region        87..423
     V_segment       87..385
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81977.1"
                     /translation="CGQGTHLPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           93 a          118 c          120 g           95 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccatga ggctccctgc tcagctcctg gggctgctat
       61 tgctctgcgt ccccggatcc agtggggatg ttgtgctgac tcagtctcca ctctccctgc
      121 ccatcacccc tggacagccg gcctccatct cctgcaggtc tagtcaaagc cttgtatata
      181 gcactggaaa cacatacttg agttggtatc aacagaagcc aggccaacct ccgaggcgcc
      241 taatttatga ggtttcttac cgggactctg gggtcccaga cagattcagc ggcagtgggg
      301 cagggacaga tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggggtttatt
      361 actgcgggca aggtacacac cttccgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004453             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17186:15780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004453
VERSION     KCVT01004453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17186:15780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..327
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81978.1"
                     /translation="CQHSYGTPFTF"
     J_segment       330..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           92 a           98 c           91 g           87 t
ORIGIN      
        1 acatgggggg ctcctgctgc tctggctccc aggcgccaga tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtaggacaag
      121 tcagaacgtt aacaactatt tacattggta tcagcagaaa ccagggaaag cccctaggct
      181 cctgatctat gctgcgtcca atttgcaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gatttcactt tcaccatcac cagcctgcaa cctgaagatg ttgcaactta
      301 ttactgtcag catagttatg gtaccccgtt cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01004454             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22160:17616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004454
VERSION     KCVT01004454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22160:17616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..384
                     /note="immunoglobulin light chain variable region"
     V_region        63..384
     V_segment       63..342
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81979.1"
                     /translation="CQQYDSDSLTF"
     J_segment       347..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           92 a          107 c           98 g           90 t
ORIGIN      
        1 acatgggggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca ggtgccaaat
       61 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      121 ccatcacttg tcgggcgact caggacattc gcagttattt agcgtggtat cagcagaaac
      181 cagggaaagc cccgaagccc ttgatctatt acgcgtccac tttggaaagt ggggtcccat
      241 caaggttcag cggcagtgga tctgggacag aattcactct caccatcagc agcctgcagc
      301 ctgaagattt tgcaacttat tactgtcaac agtatgacag tgattcgctc actttcggtg
      361 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01004455             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:9827:10022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004455
VERSION     KCVT01004455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9827:10022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81980.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaataccta tttggaatgg caccggcaga tgccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctgacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004456             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10474:4205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004456
VERSION     KCVT01004456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10474:4205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81981.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat acagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcgcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004457             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7582:10424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004457
VERSION     KCVT01004457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7582:10424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..424
                     /note="immunoglobulin light chain variable region"
     V_region        96..424
     V_segment       96..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81982.1"
                     /translation="CLQSRNSYSF"
     J_segment       390..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>429
                     /gene="IGKC"
BASE COUNT           99 a          112 c          112 g          106 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggcttca atggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcgatttctt tggaataaac ctcattcact ggtatcagca gaaaccggga caacctccta
      241 aactcctgat ttaccaagaa ttcaataaag acactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttattcctgt ggaagctgac gatgctgcac
      361 attattattg tctgcagagt aggaattctt acagttttgg ccaggggacc aaagtggaga
      421 tcaagcgag
//
LOCUS       KCVT01004458             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22679:9472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004458
VERSION     KCVT01004458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22679:9472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81983.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          107 c          108 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc agtctccatc
      121 ctccctgttt gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcaacagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004459             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22540:11105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004459
VERSION     KCVT01004459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22540:11105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..246
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81984.1"
                     /translation="CLQGYSPPWTF"
     J_segment       247..282
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>287
                     /gene="IGKC"
BASE COUNT           76 a           70 c           77 g           64 t
ORIGIN      
        1 acatggggga gacagagtca ccatcccttg ccgggcaagt catgacatta gcgattattt
       61 aagttggtat cagcagaaac caggaaaacc tcctaagcgc ctgatctatg ctgcatccag
      121 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag agttcagtct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtctac agggttatag
      241 tcccccgtgg acgttcggcc aagggaccaa ggtggaaatc aaccgag
//
LOCUS       KCVT01004460             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14816:13028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004460
VERSION     KCVT01004460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14816:13028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81985.1"
                     /translation="CMQDIQLPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           90 a          124 c          122 g          103 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattgtgat gactcagact
      121 ccactctccc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc atagtaatgg atacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacaac tcctgatcta cttgggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaagat
      361 gttggggttt attactgcat gcaagatata cagcttccgc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01004461             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12678:6136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004461
VERSION     KCVT01004461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12678:6136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..377
                     /note="immunoglobulin light chain variable region"
     V_region        95..377
     V_segment       95..340
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <317..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81986.1"
                     /translation="CMQALEFPLTF"
     J_segment       341..377
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>380
                     /gene="IGKC"
BASE COUNT           83 a           99 c          107 g           91 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccactcac cctgtccatc tcctgcaggt ctagtcagag
      121 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga ggccaggcca
      181 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      241 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgggga
      301 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      361 caaggtggag atcaaacgag
//
LOCUS       KCVT01004462             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10945:17612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004462
VERSION     KCVT01004462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10945:17612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81987.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          115 c          113 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctccccggt gccaagtgtg acatccagat gacccagtct
      121 ccatcctcct tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagacaccag gaaaagcccc gaagcctttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggattt
      301 gggacggaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004463             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:8772:3758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004463
VERSION     KCVT01004463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8772:3758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81988.1"
                     /translation="CMQGLEFPITF"
     J_segment       405..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          124 c          118 g          105 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaagctcttg gatactgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgatgt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acgctgattt cacactgcga atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagg tctagagttt ccaatcactt tcggccccgg
      421 gaccaaactg gagatcaaac gag
//
LOCUS       KCVT01004464             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22121:16490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004464
VERSION     KCVT01004464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22121:16490"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..312
                     /note="immunoglobulin light chain variable region"
     V_region        152..312
     V_segment       152..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81989.1"
                     /translation="CMQALDFPWTF"
     J_segment       275..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           67 a           86 c           91 g           71 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctggact ttccgtggac gttcggccaa gggaccaagg
      301 tggaagtcaa acgag
//
LOCUS       KCVT01004465             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22250:12348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004465
VERSION     KCVT01004465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22250:12348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81990.1"
                     /translation="CQQYDSDLFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatttg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggttctgg
      301 gacagaattc actctcacca tcaacagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc tgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004466             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5260:19551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004466
VERSION     KCVT01004466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5260:19551"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81991.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          112 c          105 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcagt tgccgggcaa gtcagggtat
      181 tgacagttct ttacattggt ttcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tgctgcatcc agtttggcaa gtggggtccc atcaaggttc agcggcagtg gatctgggcc
      301 agatttcact ctcattatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtacaaa agtttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004467             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22486:10069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004467
VERSION     KCVT01004467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22486:10069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81992.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagtc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004468             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:3078:11120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004468
VERSION     KCVT01004468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3078:11120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..416
                     /note="immunoglobulin light chain variable region"
     V_region        93..416
     V_segment       93..376
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81993.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>423
                     /gene="IGKC"
BASE COUNT           99 a          115 c          110 g           99 t
ORIGIN      
        1 atggggagac ccagtctgga cgcagcatgg acatcagggt cctcgctcag cttctcgggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacattca gttgacccag tctccatcct
      121 ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcaagt caggacattg
      181 gcaattattt agcctggtat cagcagaaac cagggaaagc ccctaacctc ctgatctata
      241 aggcgtccag tttacaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcagc ctgaagattt tgcagtttat tactgtcaac
      361 agcgtaatag ttacccgtac atgtgcagtt ttggcccggg gaccaaagtg gagatccgac
      421 gag
//
LOCUS       KCVT01004469             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:13060:10381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004469
VERSION     KCVT01004469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13060:10381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81994.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           93 a          121 c          120 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag tcggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgagctt tccagccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgagaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01004470             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18731:18597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004470
VERSION     KCVT01004470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18731:18597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..259
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81995.1"
                     /translation="CMQPLEFPWTF"
     J_segment       260..297
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           73 a           70 c           87 g           70 t
ORIGIN      
        1 acatggggcc ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg
       61 gaaacactta tttggaatgg tacctgcaga agccaggcca gtctccacag ctcttgattt
      121 atgaggtttc caaccgggcc tctggagccc cagacaggtt cagtggcagt gggtcagaca
      181 ctgatttcac actgaaaatc agcagagtgg aggctgagga tgttgtggtt tattactgca
      241 tgcaacctct agagtttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004471             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16802:5986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004471
VERSION     KCVT01004471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16802:5986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81996.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccctc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcggcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004472             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17799:6816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004472
VERSION     KCVT01004472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17799:6816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81997.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gatccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01004473             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17815:3097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004473
VERSION     KCVT01004473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17815:3097"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81998.1"
                     /translation="CMQSLEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          117 c          124 g          106 t
ORIGIN      
        1 acatgggggg gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctggccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcta gagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaatc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004474             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8735:17934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004474
VERSION     KCVT01004474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8735:17934"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV81999.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgaaga tggaaatacc tatttggaat ggcaccggca gatgccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc actctgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004475             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19813:13355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004475
VERSION     KCVT01004475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19813:13355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82000.1"
                     /translation="CQQGYSYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccctc
      121 ctccctgtcc gcatctgtgg gagacgcagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataac ttaaattggt ttcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttacccgt ggacgttcgg ccaaggggcc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004476             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15837:12981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004476
VERSION     KCVT01004476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15837:12981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..424
                     /note="immunoglobulin light chain variable region"
     V_region        104..424
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82001.1"
                     /translation="CLQYKSYPFTF"
     J_segment       388..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>428
                     /gene="IGKC"
BASE COUNT          107 a          114 c          105 g          102 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcttgctgc tctggctccc aggtgccaga tgtgacatcc aactgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag
      181 tcagggtatt agtagttatt taaattggtt tcagcagaaa acagggaagg cccctaagct
      241 cctgatctat gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atttgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtataaaa gttacccatt cactttcggc cccgggacca aactggacat
      421 caaaggag
//
LOCUS       KCVT01004477             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:6829:23561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004477
VERSION     KCVT01004477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6829:23561"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82002.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgtatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004478             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12392:12226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004478
VERSION     KCVT01004478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12392:12226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82003.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          120 c          110 g           89 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagagacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004479             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6235:12757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004479
VERSION     KCVT01004479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6235:12757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82004.1"
                     /translation="CQQHDNSPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          119 c          114 g           89 t
ORIGIN      
        1 acatgggggg gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctctctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 agggtgttag cgactggttg gcctggtatc aacagagacc agggaaagcc cctaaactcc
      241 tgatctatag ggcgtccaat ttggatacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gctacatatt
      361 actgtcaaca gcatgataat tcccctccga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004480             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19540:20438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004480
VERSION     KCVT01004480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19540:20438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82005.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctacag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004481             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6913:7869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004481
VERSION     KCVT01004481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6913:7869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82006.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaagctgga aatcaaacga g
//
LOCUS       KCVT01004482             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19159:15364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004482
VERSION     KCVT01004482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19159:15364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82007.1"
                     /translation="CMQALEFPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          123 c          116 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgataatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttccat tcaccttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01004483             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15222:18365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004483
VERSION     KCVT01004483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15222:18365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82008.1"
                     /translation="CMQSLEFPWTF"
     J_segment       406..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          110 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttggg gagccggcct ccatctcctg taggtctagt
      181 cagagcctct tggatgttga ggatggaaac acctatttgg actggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc tgacactgat ttcacactga aaatcagtag agtggaggct
      361 gaggatgttg ggttttattt ctgcatgcaa agtctggagt ttccttggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01004484             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13223:7852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004484
VERSION     KCVT01004484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13223:7852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82009.1"
                     /translation="CLQTLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat cagcagagtg gaggctgagg
      361 attttggggt ttattactgc ttacaaactc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004485             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21545:14709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004485
VERSION     KCVT01004485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21545:14709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82010.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004486             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:14831:2066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004486
VERSION     KCVT01004486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14831:2066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82011.1"
                     /translation="CQQYHSLPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          111 c          108 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggtattagta gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taacctcctg
      241 atctattata caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctacagcctg aagattttgc aaattatttc
      361 tgtcaacagt atcatagtct accgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004487             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16802:12034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004487
VERSION     KCVT01004487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16802:12034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82012.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggctc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004488             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:26547:14227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004488
VERSION     KCVT01004488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26547:14227"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..444
                     /note="immunoglobulin light chain variable region"
     V_region        117..444
     V_segment       117..400
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82013.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       406..444
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          106 a          118 c          117 g          106 t
ORIGIN      
        1 acatgggggg ttacacttcg tgcaggagtt agacccagtc tggacgcagc atggacatca
       61 gggtcctcgc tcagcttctc gggctcctgc tgctctggct cccaggtgcc agatgtgaca
      121 ctcagttgac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
      181 cttgtcggac aagtcaggac attagcagtt atttagcctg gtatcagcag aaaccaggga
      241 aagcccctaa cctcctgatc tataaggcgt ccagtttgca aagtggggtc ccatcaaggt
      301 tcagcggcag tggatctggg acagaattca ctctcaccat cagcagcctg caggctgaag
      361 attttgcagt ttattactgt caacagcgta ttggttaccc gtacatgtac agttttggcc
      421 aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01004489             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6521:13008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004489
VERSION     KCVT01004489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6521:13008"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82014.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          124 c          113 g           84 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac agattcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccaccagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004490             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11308:14614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004490
VERSION     KCVT01004490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11308:14614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..392
                     /note="immunoglobulin light chain variable region"
     V_region        72..392
     V_segment       72..355
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82015.1"
                     /translation="CQQYNTLPLTF"
     J_segment       359..392
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>396
                     /gene="IGKC"
BASE COUNT           99 a          100 c          103 g           94 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag
       61 gtgccagatg tgacattcag atgacccagt ctccatcctc cctgtctgca tctgtaggag
      121 acagagtcac catcacttgc cgggcaagtc agggcattag tagttattta aattggtatc
      181 agcagaaacc ggggaaagcc cctaaggtcc tgatctatta tacaaaccgt ttggaaagtg
      241 gggtcccatc aaggttcagt ggcagtggat ctgggacaga gttcactctc accatcagca
      301 gcctgcaacc tgaggatttt gcaacttatt actgtcaaca gtataatact ttaccgttga
      361 cgttcggcca agggaccaag gtggaaatca aaggag
//
LOCUS       KCVT01004491             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7685:16014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004491
VERSION     KCVT01004491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7685:16014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..425
                     /note="immunoglobulin light chain variable region"
     V_region        86..425
     V_segment       86..387
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82016.1"
                     /translation="CMQALEFPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           93 a          113 c          120 g          102 t
ORIGIN      
        1 acatggggga ggtcaccttc tcacaatgag gctccctgct cagctcctgg gactgctcat
       61 gctctggctc cctgtatcca gtggggacat tgtgatgacc cagactccac tctccctgcc
      121 cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagtc tcttggatag
      181 tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt ctccacagct
      241 cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca gtggcggtgg
      301 gtcagacact gatttcacac tgaaaatcag cagagtggag gctgatgatg ttggggttta
      361 ttactgcatg caagctctag agtttccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01004492             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19981:11891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004492
VERSION     KCVT01004492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19981:11891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..375
                     /note="immunoglobulin light chain variable region"
     V_region        100..375
     V_segment       100..337
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82017.1"
                     /translation="CQQYNSDPRTF"
     J_segment       341..375
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>378
                     /gene="IGKC"
BASE COUNT           92 a          105 c          100 g           81 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcag cagcctgcag cctgaagatt
      301 ttgcaactta ttactgtcaa cagtataaca gtgacccgcg cactttcggt ggagggacca
      361 aggtggagat caaacgag
//
LOCUS       KCVT01004493             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18319:17232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004493
VERSION     KCVT01004493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18319:17232"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82018.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          117 c          106 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gtcaggatat
      181 taatacctgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004494             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21711:16560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004494
VERSION     KCVT01004494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21711:16560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..387
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82019.1"
                     /translation="CLQSKNSPWSF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          115 c          115 g           99 t
ORIGIN      
        1 acatggggag cctctagttc agctctcaga aatggggtcc tgggctcctt tcctgtggat
       61 cctcctgctc tgtgctccag gctgcagtgg ggacattgtg ctgacccagt ctccagcctc
      121 tttggccgtg tctccagggc agagggccac catcacctgc agagccagtg agagtgtcag
      181 tgcctttgga ataagcctca ttcactggta tcaacagaaa ccaggacaac ctcctaaact
      241 cctgatttac caagcaatca ataaggagac tggggtccca gccaggttca gcggcagtgg
      301 gtctgggacc gatttcaccc tcacaattaa tcctgtggaa cctgacgatg gtgcagatta
      361 ttactgtctg cagagtaaga attctccgtg gtcgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01004495             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9881:20462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004495
VERSION     KCVT01004495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9881:20462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82020.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          117 c          125 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tgtcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004496             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14786:14588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004496
VERSION     KCVT01004496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14786:14588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82021.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagat
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ttatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc attgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004497             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14525:8070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004497
VERSION     KCVT01004497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14525:8070"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..408
                     /note="immunoglobulin light chain variable region"
     V_region        125..408
     V_segment       125..370
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <348..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82022.1"
                     /translation="CMQALEFPYSF"
     J_segment       371..408
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>411
                     /gene="IGKC"
BASE COUNT           93 a          105 c          113 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccat ctcctgcagg tctagtcaga gcctcatgga tagtggggat gtaaacacct
      181 atttggaatg gtacctgcag aagccaggcc agtctccaca tctcttgatt tatgaggttt
      241 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac acggatttca
      301 cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaagctc
      361 tagagtttcc gtacagtttt ggccagggga ccagagtgga gatcaaacga g
//
LOCUS       KCVT01004498             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5257:10965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004498
VERSION     KCVT01004498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5257:10965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82023.1"
                     /translation="CQQYNSLPWTF"
     J_segment       364..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          102 a          105 c          104 g           93 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag ggcattagca attatttaaa
      181 ttggtatcag gagaaaccgg ggaaagcccc taagcccctg atctattata caaatcgttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaagctg aggattttgc aacttattac tgtcaacagt ataattcttt
      361 accgtggacg ttcggccaag ggaccaaggt ggacatcaaa cgag
//
LOCUS       KCVT01004499             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11076:20633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004499
VERSION     KCVT01004499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11076:20633"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82024.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          114 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcaccctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004500             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11311:8158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004500
VERSION     KCVT01004500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11311:8158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    49..370
                     /note="immunoglobulin light chain variable region"
     V_region        49..370
     V_segment       49..331
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <310..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82025.1"
                     /translation="CQHGYGIQLTF"
     J_segment       333..370
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>373
                     /gene="IGKC"
BASE COUNT           87 a           99 c           97 g           90 t
ORIGIN      
        1 acatgggtcc tggggttcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg
       61 acccagtctc catcctccct gtctgcatct gtgggagaca gagtcaccat ctcttgccag
      121 gcgagtcagg acattagcaa tgatttagcc tggtatcagc agaaaccggg aaaagcccct
      181 aggctcctga tgtataaggc atccgctttg cagattgggg tcccatcaag gttcagcggc
      241 agtggatctg ggacagattt cactctcacc atcaacagcc tgcagcctga agattttgca
      301 acttactact gtcaacatgg ttatggtatc cagctcactt tcggtggagg gaccaaggtg
      361 gacatcaaac gag
//
LOCUS       KCVT01004501             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14660:14627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004501
VERSION     KCVT01004501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14660:14627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82026.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          122 c          115 g           85 t
ORIGIN      
        1 acatggggga ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcagc agcgtagcct ggtaccagca gaaacctggg caggctccca gactcctcat
      241 gtatggtgca tccaacaggg ccactggcat cccagacagg ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gatgttgcac tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004502             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11410:8204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004502
VERSION     KCVT01004502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11410:8204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82027.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc acagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004503             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12449:5173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004503
VERSION     KCVT01004503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12449:5173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..374
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82028.1"
                     /translation="CLQGYNIPYNF"
     J_segment       389..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          106 a          110 c          114 g           99 t
ORIGIN      
        1 acatgggggg taggagtcag aaccactcag gacacagcat ggacatgagg gtccccgctc
       61 agctcctggg gctccttctg ctctggctcc caggtgccag atgtgacatc cagttgaccc
      121 agtctccatc ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa
      181 gtcaggacat tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc
      241 gcctgatcta tgctgtgtcc agtttggaag gtggggtccc atcaagattc agcggcagtg
      301 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt
      361 attactgtct acagggttat aatatcccgt acaattttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01004504             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22132:8458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004504
VERSION     KCVT01004504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22132:8458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..312
                     /note="immunoglobulin light chain variable region"
     V_region        152..312
     V_segment       152..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82029.1"
                     /translation="CMQPLEFPWTF"
     J_segment       275..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           68 a           88 c           89 g           70 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa cctctcgagt ttccgtggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01004505             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10017:4963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004505
VERSION     KCVT01004505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10017:4963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82030.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          105 t
ORIGIN      
        1 acagggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004506             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11700:18428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004506
VERSION     KCVT01004506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11700:18428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82031.1"
                     /translation="CIQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat actgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtctgaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca ttcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004507             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20242:10221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004507
VERSION     KCVT01004507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20242:10221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82032.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004508             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16042:3869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004508
VERSION     KCVT01004508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16042:3869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82033.1"
                     /translation="CQQDYHWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gacatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcaccttaa cctggtacca ccagaagcct gggcaggctc ccaagctcct
      241 catctatggt ccatccatca gggccagcgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagaa tttactctca ccatcagcag cctggagact gaagatgttg gagtttatta
      361 ctgtcagcag gattatcact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004509             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21078:13438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004509
VERSION     KCVT01004509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21078:13438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82034.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004510             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11392:14499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004510
VERSION     KCVT01004510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11392:14499"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82035.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagttggga cattgtgctg acccagactc
      121 cactctccct gcccgtcagc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004511             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:21095:13768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004511
VERSION     KCVT01004511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21095:13768"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82036.1"
                     /translation="CQQRNGYPYMISF"
     J_segment       393..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          103 a          113 c          113 g          101 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acattcagtt gatacagtct
      121 ccatcctccc tgtctgcgtc tgtaggagac agagtcacca tcacttgtcg ggcaagtcag
      181 gacattagca gttatttagc ctggtatcag cataaaccag ggaaagcccc taagctcctg
      241 atctataggg cgtccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttac agcttattac
      361 tgtcaacagc ggaatggtta cccctacatg atcagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01004512             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10667:6992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004512
VERSION     KCVT01004512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10667:6992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..394
                     /note="immunoglobulin light chain variable region"
     V_region        73..394
     V_segment       73..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82037.1"
                     /translation="CQQHNGYPPTF"
     J_segment       360..394
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           97 a          111 c          103 g           86 t
ORIGIN      
        1 acatgggggg acatgagggt ccccgctcag ctcctggggc tcctgctgct ctggctccca
       61 ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga
      121 gacacagtca ccatcacttg tcgggcaagt cagggcatta cgaatgattt agcctggtat
      181 cagcagaaac cagggaaagc cccgaagccc ctgatctatt acgcatccaa tttggaaagt
      241 ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct caccatcagc
      301 agcctgcagc ctgaagattt tgcaacttat tattgtcaac agcataatgg ataccctccg
      361 acgttcggcc aagggaccag ggtggaaatc aaacgag
//
LOCUS       KCVT01004513             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15273:13487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004513
VERSION     KCVT01004513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15273:13487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82038.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          116 c          101 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagac tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01004514             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9151:7038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004514
VERSION     KCVT01004514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9151:7038"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82039.1"
                     /translation="CQQYFSSPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           95 a          128 c          108 g           93 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg actcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagctc cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01004515             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7233:12460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004515
VERSION     KCVT01004515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7233:12460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82040.1"
                     /translation="CQQGYSYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taatttaaat tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctctaaggc atccagtttg caaagtggga ttccctctcg gctcagcggc agtggatctg
      301 gggcggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttactact
      361 gtcaacaggg ttatagttac ccgtggacat tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004516             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25468:13267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004516
VERSION     KCVT01004516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25468:13267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82041.1"
                     /translation="CQQGYTYLYSF"
     J_segment       379..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          114 c          105 g          100 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgtt ggagacacag tcaccatcac ttgccaggcg agtcaagcca
      181 ttgccaataa tttaaattgg tatcagcaga aaccaggaaa agcccctaaa gtcctgatct
      241 atagggcatc cagtttgcaa agtgggtttc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tacttacttg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004517             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21775:3983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004517
VERSION     KCVT01004517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21775:3983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82042.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc cccgacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtaga gatcaaacga g
//
LOCUS       KCVT01004518             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18257:6575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004518
VERSION     KCVT01004518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18257:6575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..455
                     /note="immunoglobulin light chain variable region"
     V_region        122..455
     V_segment       122..417
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <395..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82043.1"
                     /translation="CLQSKNSPWTF"
     J_segment       418..455
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>458
                     /gene="IGKC"
BASE COUNT          109 a          121 c          124 g          104 t
ORIGIN      
        1 acatggggaa aggcagcttg tcaggggccc tgaggagcag cctctagttc agctctcaga
       61 aatggggtcc tgggctcctt tcctgtggat cctcctgctc tgtgctccag gctgcaatgg
      121 ggacattgtg ctgacccagt ctccagcctc tttggccgtg tctccagggc agagggccac
      181 catcacctgc agagccagtg agagtgtcag tgtctttgga ataaacctca ttcactggta
      241 tcagcagaaa ccaggacaac ctcctaaacc cctgatttac caagcatcca ataaagaaac
      301 tggggtccca gccaggttca gcggcagtgg gtctgggacc gatttcaccc tcacaattaa
      361 tcctgtggaa gctgacgatg ctgcagatta ttattgtctg cagagtaaga attctccgtg
      421 gacgtttggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01004519             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16507:8737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004519
VERSION     KCVT01004519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16507:8737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82044.1"
                     /translation="CQQGYSFPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           95 a          122 c          106 g          100 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcag tagtttaagc tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctttagggc atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagtc tccagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagtttc cccttcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004520             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14438:6423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004520
VERSION     KCVT01004520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14438:6423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82045.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           98 a          119 c          123 g          106 t
ORIGIN      
        1 acatgggggg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gagtccactc tccctgtccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga gatttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca cagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagag tttccgctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01004521             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:8647:12779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004521
VERSION     KCVT01004521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8647:12779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82046.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          123 c          115 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaagtgga aatcaaacga g
//
LOCUS       KCVT01004522             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18993:5152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004522
VERSION     KCVT01004522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18993:5152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82047.1"
                     /translation="CQQYNSVPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccgtg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaagcaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcat cttattactg
      361 tcaacagtat aacagtgtcc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004523             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:15242:15236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004523
VERSION     KCVT01004523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15242:15236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82048.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc ctcggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaagctc tggaatttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004524             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9666:3920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004524
VERSION     KCVT01004524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9666:3920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82049.1"
                     /translation="CMQSLELPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          117 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcgtcca tctcctgtag gtctagtcag
      181 agcctcgtgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagcttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01004525             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:27560:12714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004525
VERSION     KCVT01004525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:27560:12714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82050.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggggtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004526             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22079:3964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004526
VERSION     KCVT01004526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22079:3964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82051.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          109 c          104 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgtcgg gcaagtcagg
      181 acattaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatag aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004527             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12012:14497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004527
VERSION     KCVT01004527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12012:14497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82052.1"
                     /translation="CQQYNSDWRTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          114 c          112 g           91 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgactgg cgcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004528             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20656:8721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004528
VERSION     KCVT01004528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20656:8721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82053.1"
                     /translation="CMQVLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggaa cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gcacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagttc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004529             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20824:3245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004529
VERSION     KCVT01004529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20824:3245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82054.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004530             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18622:17418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004530
VERSION     KCVT01004530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18622:17418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82055.1"
                     /translation="CQQGSSFPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          107 a          116 c          105 g           99 t
ORIGIN      
        1 acatgggggg catgagcaaa actgacaagt caaggcagga agatgttgtc tccatcacaa
       61 ctcattgggt ttctgctgct ctgggttcca gcctccaaga gtgaaattgt gctgactcag
      121 tctccagcct ttcggtctgt gactctaaag gagaaagtca ccatcacctg ccaggccagt
      181 cagggcattg atagtgcctt acactggtac cagcagaaac cggatcagtc tccaaagctc
      241 ctcatcaagt atgcttccca gtccatctca ggggccccct caaggttcag tggcagtgga
      301 tctgggacag atttcaccct caccatcaat agcctggaag ctgaagatgc tgcgacgtat
      361 tactgtcagc agggtagtag tttcccattc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01004531             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14778:12209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004531
VERSION     KCVT01004531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14778:12209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82056.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtcaagtc
      181 agagcctctt ggatagtgag gatgaaaaca cctatttgga atggtacgtg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccatccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa catcagcaga gtggaggctg
      361 aggatcttgg ggtttattac tgcatgcaag ctctagagtt tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01004532             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:19773:14937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004532
VERSION     KCVT01004532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19773:14937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82057.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agagccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcgtccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgcagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggagg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004533             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8782:16057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004533
VERSION     KCVT01004533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8782:16057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82058.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          117 c          105 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gtcaggatat
      181 taataccttg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004534             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24590:6338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004534
VERSION     KCVT01004534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24590:6338"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..313
                     /note="immunoglobulin light chain variable region"
     V_region        114..313
     V_segment       114..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82059.1"
                     /translation="CMQYRHIPFTF"
     J_segment       276..313
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           73 a           81 c           82 g           80 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagtct
      121 ccacagccct tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt
      181 ggcagtgggt cagacactga tttcacactg aaaattaaca gagtggaggc tgaggatgtt
      241 gggatttata tctgcatgca atatagacac attccattca ctttcggccc cgggaccaaa
      301 ctggatatca aacgag
//
LOCUS       KCVT01004535             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17175:14465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004535
VERSION     KCVT01004535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17175:14465"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..415
                     /note="immunoglobulin light chain variable region"
     V_region        101..415
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82060.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>425
                     /gene="IGKC"
BASE COUNT          106 a          117 c          107 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcggtggatc
      301 tgggacagag ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacaa tatgacagtg acccattcac tttcggcccc gggaccaaac tggattccaa
      421 acgag
//
LOCUS       KCVT01004536             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9307:14867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004536
VERSION     KCVT01004536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9307:14867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82061.1"
                     /translation="CQQGYSYPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          120 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg atgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcacg
      181 gcattggcaa taatttaaat tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctatacggc atccaggtta caaggtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcggcc tgcagcctga agatcttgcc acttattact
      361 gtcaacaggg ttatagttac ccattcactt tcggtcccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004537             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18862:4687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004537
VERSION     KCVT01004537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18862:4687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..404
                     /note="immunoglobulin light chain variable region"
     V_region        99..404
     V_segment       99..367
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82062.1"
                     /translation="CQQNSNWPLTF"
     J_segment       368..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           98 a          118 c          109 g           82 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcagaaac ctgggcaggc tcccagactc ctcatctatg gtgcatccaa
      241 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcactct
      301 caccatcagc agcctggagc ctgaagatgt tgcactttat tattgtcagc agaatagtaa
      361 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01004538             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19602:17377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004538
VERSION     KCVT01004538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19602:17377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..394
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82063.1"
                     /translation="CMQSLDLPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          127 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgcaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagaccttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004539             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:26782:15896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004539
VERSION     KCVT01004539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26782:15896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82064.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          121 c          111 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagggg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01004540             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14955:12741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004540
VERSION     KCVT01004540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14955:12741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82065.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggtc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004541             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14538:13189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004541
VERSION     KCVT01004541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14538:13189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82066.1"
                     /translation="CQQYNSLPYSF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          106 a          110 c          113 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggcccca ggtgccagat gtgacattga gatgacccag
      121 tctccatcct ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt
      181 cagggcgtta acgtttattt aaattggtat cagcagaaac cggggaaagc ccctaagccc
      241 ctgatctttt atgcaaaccg tttggaacgt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcaac ctgaagattt tgcaagttat
      361 tattgtcaac agtataatag tttaccgtac agttttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01004542             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22065:6246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004542
VERSION     KCVT01004542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22065:6246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82067.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca aaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004543             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14708:3432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004543
VERSION     KCVT01004543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14708:3432"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82068.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcaaca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004544             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:7751:17544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004544
VERSION     KCVT01004544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:7751:17544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82069.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagtc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004545             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16014:7655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004545
VERSION     KCVT01004545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16014:7655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82070.1"
                     /translation="CQQYNSDTRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          114 g           93 t
ORIGIN      
        1 atggggagga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggagattggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagt ataacagtga cacgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004546             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15798:8792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004546
VERSION     KCVT01004546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15798:8792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82071.1"
                     /translation="CQQHADSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          120 c          111 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggtattagca actggttggc ctggtatcaa cagagaccag ggaaagcccc taaggtcctg
      241 atctatacga catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aaccggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc aacgtattac
      361 tgtcaacagc atgctgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004547             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23688:10273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004547
VERSION     KCVT01004547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23688:10273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82072.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          119 c          104 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctctag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01004548             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12591:21501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004548
VERSION     KCVT01004548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12591:21501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82073.1"
                     /translation="CMQALEFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct tagagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctacagag gccaggccag
      241 tctccacagc tcttaattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004549             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14083:5003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004549
VERSION     KCVT01004549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14083:5003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82074.1"
                     /translation="CLQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttagcagagt ggaggctgag
      361 gatgttgggg tttattactg cttgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004550             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4804:17013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004550
VERSION     KCVT01004550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4804:17013"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82075.1"
                     /translation="CQQDFDWPPPF"
     J_segment       402..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          128 c          115 g           91 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc
      241 tcccaaactc ctcctctatg gtgcatccac cagggccacc ggcatcccag acaggttcaa
      301 tgccagtggg tctggaacag agttttctct caccatcagc agcctggagc ctgaagatgt
      361 tggaatttat tattgtcagc aggattttga ctggcctccg ccgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01004551             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12282:16522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004551
VERSION     KCVT01004551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12282:16522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82076.1"
                     /translation="CLQYKTYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          110 c          106 g           99 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcttctgta ggagacactg tcaccatcac ttgccgggca agtcagggta
      181 ttgctggtta tttaaattgg tttcagaaga aaccagggaa agcccctaag ctcctgatcc
      241 aagctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtataa aacttatccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004552             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24288:10007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004552
VERSION     KCVT01004552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24288:10007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82077.1"
                     /translation="CMQPLDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcag ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaacct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004553             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:12743:13119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004553
VERSION     KCVT01004553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12743:13119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..393
                     /note="immunoglobulin light chain variable region"
     V_region        111..393
     V_segment       111..355
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82078.1"
                     /translation="CGQGTHLPWTF"
     J_segment       356..393
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           95 a          102 c          112 g           87 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gcctccatct
      121 cctgcaggtc tagtcaaagc cttgtacaca tcaatggaaa cacatacttg agttggtatc
      181 agcagaaccc aggccaacct ccaaggcgcc taatttatga ggtttctaac cgggactctg
      241 gggtcccaga cagattcagc ggcagtgggg cagggacaga tttcacactg aaaatcagca
      301 gagtggaggc tgaggatgtt gggctttatt actgcgggca aggtacacac cttccgtgga
      361 cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004554             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10644:4074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004554
VERSION     KCVT01004554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10644:4074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82079.1"
                     /translation="CLQYKSFPYTF"
     J_segment       390..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          116 c          100 g           97 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgccaccat cacttgccgg acaagtcaag
      181 gtataaccaa ttatttacat tggtttcagc agaaaccagg gagagcccct aagctcctga
      241 tctatgaaac atcgagtttg acaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggacagaatt cactctcact atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagtttc ccgtacacct ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01004555             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10766:4690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004555
VERSION     KCVT01004555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10766:4690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..247
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82080.1"
                     /translation="CQQYDSDSLTF"
     J_segment       252..289
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>292
                     /gene="IGKC"
BASE COUNT           75 a           71 c           81 g           65 t
ORIGIN      
        1 acatgggctg taggagacag agtcaccatc acttgtcggg cgactcagga cattcgcagt
       61 tatttagcgt ggtatcagca gagaccaggg aaagccccga ggcccttgat ctattacgcg
      121 tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc
      181 actctcacca tcagcagcct gcagcctgaa gattttgcaa cctattactg tcaacagtat
      241 gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004556             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16392:6585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004556
VERSION     KCVT01004556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16392:6585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    214..368
                     /note="immunoglobulin light chain variable region"
     V_region        214..368
     V_segment       214..330
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82081.1"
                     /translation="CMQALDFPFTF"
     J_segment       331..368
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           83 a          107 c           94 g           87 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 ccccctccct gcccgtcacc cttggagagg cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttcga tactgaagaa ggaaacacct atttggagtc ccagacaggt tcagtggcag
      241 tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggact
      301 ttattactgc atgcaggctc tagactttcc attcactttc ggccccggga ccaaactgga
      361 tatcaaacga g
//
LOCUS       KCVT01004557             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15770:7256
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004557
VERSION     KCVT01004557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15770:7256"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82082.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcaatggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004558             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22580:18406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004558
VERSION     KCVT01004558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22580:18406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82083.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          104 g          101 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtag ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattttgc aaaccgtttg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggactgaatt cactctcacc atcagcagcc tgcaccctga tgattttgca acttattact
      361 gtcaacaata taatagttta ccgtggacgt tcggcctagg gaccaaggtc gatatcaaac
      421 gag
//
LOCUS       KCVT01004559             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:5875:22418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004559
VERSION     KCVT01004559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5875:22418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82084.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          125 c          111 g           85 t
ORIGIN      
        1 acatggggga ggaactactc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004560             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:2293:14949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004560
VERSION     KCVT01004560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:2293:14949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82085.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcgggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004561             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9816:11685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004561
VERSION     KCVT01004561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9816:11685"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82086.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          124 c          117 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccgctctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgataa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cattcacctt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01004562             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22132:8019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004562
VERSION     KCVT01004562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22132:8019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82087.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc ttagagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttaattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtgggagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004563             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:21622:11380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004563
VERSION     KCVT01004563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21622:11380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82088.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc ttgagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004564             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18414:9148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004564
VERSION     KCVT01004564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18414:9148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82089.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          127 c          112 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcaacttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgc catcccatcc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggaggtcaa
      421 acgag
//
LOCUS       KCVT01004565             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20076:5434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004565
VERSION     KCVT01004565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20076:5434"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82090.1"
                     /translation="CQQHNFYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          120 c          108 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag cagaaaccag ggagagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac cgtcagcagc ctgcagcccg aagattttgc aatttattac
      361 tgtcaacagc ataattttta ccctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004566             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11985:12303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004566
VERSION     KCVT01004566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11985:12303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82091.1"
                     /translation="CMQSLEIPPTF"
     J_segment       406..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgggg atggaaacac ctatttggat tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaatc tctagagatt cctcccactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004567             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20283:8489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004567
VERSION     KCVT01004567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20283:8489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82092.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttttcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01004568             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6731:7382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004568
VERSION     KCVT01004568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6731:7382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82093.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          112 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca gaatcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttgaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tgtattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca gcttattact
      361 gtcaacaata taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004569             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8156:10008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004569
VERSION     KCVT01004569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8156:10008"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82094.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          105 t
ORIGIN      
        1 acagggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttttgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01004570             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14189:15803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004570
VERSION     KCVT01004570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14189:15803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82095.1"
                     /translation="CEQYNSLPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          110 a          111 c          102 g           98 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagt atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 gttaacattt atttaaattg gtatcaccag aaaccgggga aagcccctaa gctcctgatc
      241 tattatacaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattactgt
      361 gaacaataca atagtttacc gtacactttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01004571             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:3640:10081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004571
VERSION     KCVT01004571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3640:10081"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..386
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82096.1"
                     /translation="CQHGYGVPWTL"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          119 c          112 g           94 t
ORIGIN      
        1 acatgggggt aggagtcagt cccagtcagg acacagcatg gacatgaggg cccccactca
       61 gctcctgggg ttcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gccaggcgag
      181 tcaggccatc ggtaataatt tagtctggta tcagcagaaa ccggggaaag cccctaacct
      241 cctgatctat aaggcatcca ctttgcaaag tggggtccca tctaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcaa cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcag catggttatg gtgtcccgtg gacgctcggc caagggacca agatggaaat
      421 caaacgag
//
LOCUS       KCVT01004572             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14537:21703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004572
VERSION     KCVT01004572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14537:21703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82097.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004573             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5072:15881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004573
VERSION     KCVT01004573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5072:15881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82098.1"
                     /translation="CQQYNSLPYIF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          110 c          104 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aacccctgat
      241 ctattataga aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtacatttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004574             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12989:5046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004574
VERSION     KCVT01004574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12989:5046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82099.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          110 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004575             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22434:9485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004575
VERSION     KCVT01004575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22434:9485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..394
                     /note="immunoglobulin light chain variable region"
     V_region        113..394
     V_segment       113..356
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <334..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82100.1"
                     /translation="CMQSLEFPLTF"
     J_segment       357..394
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>397
                     /gene="IGKC"
BASE COUNT           90 a           99 c          111 g           97 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccatctcc
      121 tgcaggtcta gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac
      181 ctgcagaagc caggccagtc tccacagctc ttgatttatg aggtctccaa ccgggcctct
      241 ggagtcccag acaggttcag tggcagtggg tcagacacta atttcacact gagaatcagt
      301 agagtggagg ctgaggatgt tggggtttat tactgcatgc aatctctaga gtttccgctc
      361 actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01004576             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17703:10046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004576
VERSION     KCVT01004576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17703:10046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82101.1"
                     /translation="CQQDYSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          119 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcatctta gcctggtacc accagaaacc tgggcaggct cccaagtccc
      241 tcatctatgg tgcaaccagt agggccaccg gcatcccaga caggttaggt ggcagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggcgtttatt
      361 actgtcagca ggattatagc tggccactca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004577             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14600:13752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004577
VERSION     KCVT01004577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14600:13752"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82102.1"
                     /translation="CLQGYITPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          112 c          112 g          100 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttgcaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 attgtctaca gggttatatt accccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004578             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9361:11537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004578
VERSION     KCVT01004578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9361:11537"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82103.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatgggggt tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004579             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19901:17986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004579
VERSION     KCVT01004579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19901:17986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82104.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004580             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11727:12084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004580
VERSION     KCVT01004580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11727:12084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..294
                     /note="immunoglobulin light chain variable region"
     V_region        7..294
     V_segment       7..254
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82105.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       264..294
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>301
                     /gene="IGKC"
BASE COUNT           81 a           73 c           78 g           69 t
ORIGIN      
        1 acatgggcat ctgtaggaga cagagtcacc atcacttgtc gggcaagtca ggacattggc
       61 aattatttag cctggtatca gcagaaacca gggaaagccc ctaacctcct gatctataag
      121 gcgtccagtt tacaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa
      181 ttcactctca ccatcagcag cctgcagcct gaagattttg cagtttatta ctgtcaacag
      241 cgtaatagtt acccgtacat gtgcagtttt ggcccgggga ccaaagtgga gatccgacga
      301 g
//
LOCUS       KCVT01004581             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17203:3082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004581
VERSION     KCVT01004581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17203:3082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82106.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcaactc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004582             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:9253:5646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004582
VERSION     KCVT01004582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9253:5646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82107.1"
                     /translation="CQQYDSLPYSF"
     J_segment       384..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          105 a          109 c          111 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 cttcctccct gtctgcgtct gtaggagaca cagtcaccat tacttgccgg gcaagtcagg
      181 gcattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agcggatctg
      301 ggacagaatt cactctcacc atcagtggcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta tgatagttta ccatacagtt ttggccaggg gaccaaagtg gagatcagac
      421 gag
//
LOCUS       KCVT01004583             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23619:5564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004583
VERSION     KCVT01004583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23619:5564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82108.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          114 c          110 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa tttactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcactcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004584             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25598:17848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004584
VERSION     KCVT01004584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25598:17848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..429
                     /note="immunoglobulin light chain variable region"
     V_region        98..429
     V_segment       98..393
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82109.1"
                     /translation="CLQSKNSPWTF"
     J_segment       394..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>434
                     /gene="IGKC"
BASE COUNT           99 a          116 c          117 g          102 t
ORIGIN      
        1 acatggggag gagcagcctc tagttcagct ctcagaaatg gggtcctggg ctcctttcct
       61 gtggatcctc ctgctctgtg ctccaggctg caatggggac attgtgctga cccagtctcc
      121 agcctctttg gccgtgtctc cagggcagag ggccaccatc acctgcagag ccagtgagag
      181 tgtcagtttg tttggaatca gcctcattca ctggtatcag cagaaaccag gacaacctcc
      241 taaactcctg atttaccaag cattcaacac agagactggg gtcccagtca ggttcagcgg
      301 cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaacctg atgatgctgc
      361 agattattac tgtctgcaga gtaagaattc tccgtggacg ttcggccaag ggaccaaggt
      421 ggaaatcaag cgag
//
LOCUS       KCVT01004585             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22071:6927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004585
VERSION     KCVT01004585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22071:6927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82110.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccagtttgg aaagtggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc actctcacca tcagcggcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01004586             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:24000:15643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004586
VERSION     KCVT01004586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24000:15643"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82111.1"
                     /translation="CIQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atccaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004587             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19463:2810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004587
VERSION     KCVT01004587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19463:2810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82112.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca gagctcttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg ctttattact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004588             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21221:17352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004588
VERSION     KCVT01004588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21221:17352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82113.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004589             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:9937:13773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004589
VERSION     KCVT01004589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9937:13773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82114.1"
                     /translation="CMQDIQLPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           90 a          124 c          122 g          103 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattgtgat gactcagact
      121 ccactctccc tggccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc atactaatgg atacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacaac tcctgatcta cttgggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaagat
      361 gttggggttt attactgcat gcaagatata cagcttccgc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01004590             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14006:20491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004590
VERSION     KCVT01004590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14006:20491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82115.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggcaaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004591             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:10435:17702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004591
VERSION     KCVT01004591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10435:17702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82116.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccacc agggccaccg gcatcccgga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004592             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5824:11859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004592
VERSION     KCVT01004592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5824:11859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82117.1"
                     /translation="CLQGYYSPYNF"
     J_segment       383..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT           99 a          115 c          111 g           98 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcctcg gtaggagaca gagtcaccat cacttgccgg gcaagtcggg
      181 acattagcga ttatttaagt tggtatcagc agaaaccagg agaagctcct aagcgcctga
      241 tctatgctgc atccagtttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacactatt cactctcacc atcagcagcc tgcagcctga agattttgca gcttattact
      361 gtctgcaggg ttattattcc ccgtacaatt ttggccaggg gaccaaagtg gagatcaagc
      421 gag
//
LOCUS       KCVT01004593             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21577:15522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004593
VERSION     KCVT01004593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21577:15522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82118.1"
                     /translation="CMQSTKDPLTF"
     J_segment       399..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          124 c          109 g          103 t
ORIGIN      
        1 acatggggat caggactcct cagttcatct tctcacgatg agactccctg ctcagctcct
       61 cgggctgttg atgctctggg tccctgaatc cagtggggat attgtgatga cccagactcc
      121 actgtcgctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 ccttctgcat actaatggat acacctattt gcattggtac ctgcagaagc caggccagtc
      241 tccacggctc ctgatctata aagttaccaa tcgggaatct ggggtcccag acaggttcac
      301 cggcagtggg tcaggcacag atttcacact gaaaatcagc agggtggagc ctgaggatgt
      361 tggtgtttat tactgcatgc aaagtacaaa agatcccctc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01004594             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17714:10338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004594
VERSION     KCVT01004594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17714:10338"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..279
                     /note="immunoglobulin light chain variable region"
     V_region        7..279
     V_segment       7..242
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <219..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82119.1"
                     /translation="CMQALEFPLTF"
     J_segment       243..279
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>282
                     /gene="IGKC"
BASE COUNT           71 a           60 c           84 g           67 t
ORIGIN      
        1 acatgggcag gtctagtcag agcctcttgg atagtgagga tggaaacacc tatttggaat
       61 ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaaccggg
      121 cctctggagt cccagacagg atcagtggca gtgggtcaga cactgatttc acactgaaaa
      181 tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct ctagagtttc
      241 ctctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004595             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:25863:12118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004595
VERSION     KCVT01004595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25863:12118"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82120.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004596             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18860:20550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004596
VERSION     KCVT01004596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18860:20550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82121.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          119 c          128 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcgc ccttggagag ccggcctcca tctcctgtgg gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaggccaggc
      241 cagtctccac agctgttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gcgggccaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatttctg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aattcaaacg ag
//
LOCUS       KCVT01004597             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8860:18543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004597
VERSION     KCVT01004597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8860:18543"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82122.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggttccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtcg gtctagtcag
      181 agcctcttgg ctagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaagtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004598             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18974:3074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004598
VERSION     KCVT01004598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18974:3074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82123.1"
                     /translation="CQQYNSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          113 c          113 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tagcagttat ttagcgtggt atcggcagag gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaag gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttggaactt attactgtca
      361 acagtataac agtgactcgc tcactttcgg tggagggacc aaggtggata tcaaacgag
//
LOCUS       KCVT01004599             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13496:14122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004599
VERSION     KCVT01004599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13496:14122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..426
                     /note="immunoglobulin light chain variable region"
     V_region        90..426
     V_segment       90..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82124.1"
                     /translation="CGQGTHLPLTF"
     J_segment       389..426
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g           94 t
ORIGIN      
        1 acatggggat caggactcct cagttcacca tgaggctccc tgctcagctc ctggggctgc
       61 tattgctctg cgtccccgga tccagtgggg atgttgtgat gactcagtct ccactctccc
      121 tgcccatcac ccctggacag ccggcctcca tctcctgcag gtccagtcaa agccttgtat
      181 acatcactgg aaacacatac ttgagttggt atcagcagaa gccaggccaa cctccaaggc
      241 gcctaattta tgaggtttct aaccgggact ctggggtccc agacagattc agcggcagtg
      301 gggcggggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttgggattt
      361 attactgcgg gcaaggtaca caccttccgc tcactttcgg cggagggacc aaggtggaga
      421 tcaaacgag
//
LOCUS       KCVT01004600             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21608:5421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004600
VERSION     KCVT01004600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21608:5421"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82125.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004601             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18249:7172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004601
VERSION     KCVT01004601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18249:7172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    170..341
                     /note="immunoglobulin light chain variable region"
     V_region        170..341
     V_segment       170..304
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82126.1"
                     /translation="CQQYNSLPVTF"
     J_segment       306..341
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           78 a           95 c           94 g           77 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caaaccgttt
      181 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagagt tcactctcac
      241 catcagcagc ctgcagcctg aagattttgc gacttattac tgtcaacagt ataatagttt
      301 acctgtcact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01004602             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10459:4452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004602
VERSION     KCVT01004602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10459:4452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82127.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagtcc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004603             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17876:8047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004603
VERSION     KCVT01004603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17876:8047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82128.1"
                     /translation="CQQYNSEPRTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          117 c          114 g           91 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaaccc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gagccgcgca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004604             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:7412:3272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004604
VERSION     KCVT01004604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7412:3272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82129.1"
                     /translation="CQQYYSTPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          105 a          111 c          123 g          102 t
ORIGIN      
        1 acatggggga gctacaacag gcaggcaggg gcagcaagat ggtgtcacag acccaagtct
       61 tcatttccct gttgctctgg atctctggtg tctgtgggga cattgtgatg acccagtcgc
      121 cagactccct ggctgtgtct ctgggagaga gggtcaccat caactgcaag tccagccaga
      181 gtcttttacg cgtctccaac aataggaact acttagcctg gtatcagcag aaaccagggc
      241 aggctcctaa attgctcatt tactgggcat ctacccggga attcgggatc cctaaccgat
      301 tcagtggcag tggatctggg tcagatttca ctctcaccat cagtggcctg caggctgaag
      361 atgtggcagt gtattactgt cagcagtatt atagcactcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004605             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17980:8051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004605
VERSION     KCVT01004605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17980:8051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82130.1"
                     /translation="CQQYDSDSLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          118 c          111 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tcccccctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      181 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01004606             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20831:16167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004606
VERSION     KCVT01004606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20831:16167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82131.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccgaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004607             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23260:13250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004607
VERSION     KCVT01004607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23260:13250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82132.1"
                     /translation="CQQSYRYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          109 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ctggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atgtatcttg catccacttt gcagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagatgctgc aacttattac
      361 tgtcagcaga gttatcgtta tccgctcact ttcggtggag ggacccaggt ggaaatcaat
      421 cgag
//
LOCUS       KCVT01004608             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17630:6989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004608
VERSION     KCVT01004608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17630:6989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82133.1"
                     /translation="CQQSYRYPLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatgtatctt acatccactt tgcagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctcg ccatcagcag cctgcagcct gaagatgctg caacttatta
      361 ctgtcagcag agttatcgtt atccgctcac tttcggtgga gggacccagg tggaaatcaa
      421 tcgag
//
LOCUS       KCVT01004609             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14435:9468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004609
VERSION     KCVT01004609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14435:9468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82134.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggtagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01004610             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17438:14238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004610
VERSION     KCVT01004610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17438:14238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82135.1"
                     /translation="CQQYTSFPLTF"
     J_segment       384..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          101 a          122 c          107 g           92 t
ORIGIN      
        1 actggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtgagga
      181 cgttagcagt catttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctgat
      241 ctattttgca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcaacctgag gactttgcaa cctatcactg
      361 tcaacagtac actagtttcc ccctcacttt cggccccggg accaaactgg atatcaagcg
      421 ag
//
LOCUS       KCVT01004611             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10094:13024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004611
VERSION     KCVT01004611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10094:13024"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82136.1"
                     /translation="CQQHNTYPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          118 c          104 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 acattagtaa tgatttagcc tggtatcagc agaaaccagg gaaagcccca aagcccctga
      241 tcttttacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taatacttac ccgtacactt ttggccaggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004612             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19505:14320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004612
VERSION     KCVT01004612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19505:14320"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82137.1"
                     /translation="CIQSLEFPWTF"
     J_segment       348..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           85 a           99 c          108 g           95 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccac cggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccttctcc tgtaggtcta
      121 gtcacagcct cttggatagt gaggatggaa atatccattt ggattggtat ctgcagaagc
      181 caggccagtc tccacacctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggtttag tggcagtggg tcagacactg atttcacact gaaaatcagc agggtggagg
      301 ctgaggatgt tggggtttac tactgcatac aatctctaga gtttccttgg acgttcggcc
      361 aggggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01004613             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20041:19132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004613
VERSION     KCVT01004613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20041:19132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82138.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          118 c          118 g           95 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcact atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcagcaga acccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01004614             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14730:4847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004614
VERSION     KCVT01004614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14730:4847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82139.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 cccaagtgga gatcaaacga g
//
LOCUS       KCVT01004615             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20973:15860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004615
VERSION     KCVT01004615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20973:15860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..322
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82140.1"
                     /translation="CMQALEFPLTF"
     J_segment       323..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           84 a           91 c          101 g           86 t
ORIGIN      
        1 acatggggga tccactgggg acattgtgct gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag aacctcttgg atagtgagga
      121 tggaaacacc tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat
      181 ttatgaggtt tccaatcggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct ctagaatttc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      361 ag
//
LOCUS       KCVT01004616             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:1900:13568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004616
VERSION     KCVT01004616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:1900:13568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82141.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004617             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:11783:9086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004617
VERSION     KCVT01004617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11783:9086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82142.1"
                     /translation="CMQARDFPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           92 a          124 c          120 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctgggtcc attggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttcgata gtgaggaagg aaacacctat ttggagtggt acctgcagag gccaggccag
      241 tctccacagg tcttgattta tggggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgagaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcga gactttccat tcactttcgg ccccgggacc
      421 aaactggaca tcaaacgag
//
LOCUS       KCVT01004618             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10925:10817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004618
VERSION     KCVT01004618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10925:10817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82143.1"
                     /translation="CGQGTHLPLTF"
     J_segment       394..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g           97 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgctgactc agtctccact
      121 ctccctgccc atcacccctg gacagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tgtatatagc actggaaaca catacttgag ttggtatcaa cagaagccag gccaacctcc
      241 gaggcgccta atttatgagg tttcttaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 ggtttattac tgcgggcaag gtacacacct tccgctcact ttcggcggag ggaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01004619             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7174:9006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004619
VERSION     KCVT01004619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7174:9006"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82144.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagaa actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004620             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13268:8445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004620
VERSION     KCVT01004620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13268:8445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82145.1"
                     /translation="CMQSLDFPLTF"
     J_segment       404..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           96 a          122 c          119 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtt atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcagt ctctagattt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaat cgag
//
LOCUS       KCVT01004621             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14498:20334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004621
VERSION     KCVT01004621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14498:20334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82146.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccactgggga cattgtgatg acgcagactc
      121 catactccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc tcagacagat
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggttga gatcaaacga g
//
LOCUS       KCVT01004622             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18839:18911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004622
VERSION     KCVT01004622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18839:18911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82147.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          118 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004623             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12547:10504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004623
VERSION     KCVT01004623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12547:10504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82148.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcatgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tgtggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004624             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5034:8877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004624
VERSION     KCVT01004624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5034:8877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82149.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          124 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaacgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccgc agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004625             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8811:2647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004625
VERSION     KCVT01004625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8811:2647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82150.1"
                     /translation="CLQYKSFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          114 c          102 g          101 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtgggaga cactgtcacc atcacttgcc ggacaagtca
      181 aggtattacc aattatttac attggtttca gcagaaacca gggaaagccc ctaagctcct
      241 gatctatgaa acatccagtt tggtcagtgg ggtcccatca aggttcagcg gcagtgcatc
      301 tgggacagaa ttcactctca ccatcagcag cctacagcct gaagattttg catcttatta
      361 ctgtctacag tataaaagtt tcccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004626             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15303:8884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004626
VERSION     KCVT01004626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15303:8884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..300
                     /note="immunoglobulin light chain variable region"
     V_region        8..300
     V_segment       8..266
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <244..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82151.1"
                     /translation="CMQYTHMPLTF"
     J_segment       267..300
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>307
                     /gene="IGKC"
BASE COUNT           76 a           74 c           88 g           69 t
ORIGIN      
        1 acatgggctg gacagccggc ctccatctcc tgcaggtcta gtcagagcct cttggacagt
       61 gaagatggaa acacctattt ggattggtac ctacaaaagc cgggccagtc gccacagccc
      121 ttgatttatg aggtttccaa tcgggcctct ggagtccctg acaggttcag tggcagtggg
      181 tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt tgggatttat
      241 tactgcatgc aatatacaca catgccgctc actttcggcg gagggaccaa ggtggagatc
      301 gaacgag
//
LOCUS       KCVT01004627             356 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23981:24099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004627
VERSION     KCVT01004627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 356)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23981:24099"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..351
                     /note="immunoglobulin light chain variable region"
     V_region        14..351
     V_segment       14..316
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <293..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82152.1"
                     /translation="CMQALEFPFTF"
     J_segment       318..351
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>356
                     /gene="IGKC"
BASE COUNT           78 a           90 c          102 g           86 t
ORIGIN      
        1 acatgggact ggggacattg ttatgaccca gactccactc tccctgcccg tcacccttgg
       61 agagccggcc tccatctcct gcaggtctag tcagagcctc tttgatattg aggaggggac
      121 cacctatttg gaatggtacc tgcagaggcc tggccagtct ccacagctct tgatttatga
      181 ggtttccaac cgggcctctg gagtcccaga caggttcagt ggcagtgggt cagacactga
      241 tttcacactg aaaatcaaca gagtggaggc tgaggatggt ggggtttatt actgcatgca
      301 agctctagag tttcctttca ctttcggcgg agggaccaag gtggagatca agcgag
//
LOCUS       KCVT01004628             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7973:4336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004628
VERSION     KCVT01004628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7973:4336"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..424
                     /note="immunoglobulin light chain variable region"
     V_region        85..424
     V_segment       85..387
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82153.1"
                     /translation="CIQSLEFPWTF"
     J_segment       388..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           92 a          113 c          116 g          106 t
ORIGIN      
        1 acatggggag gtcaccttct cacaatgagg ctccctgctc agctcctggg actgctaatg
       61 ctctggctcc ctggatccac tggggacatt gtgatgaccc agactccact ctccctgccc
      121 gtcacccttg gagagccggc ctccttctcc tgtaggtcta gtcacagcct cttggatagt
      181 gaggatggaa atatccattt ggattggtat ctgcagaagc caggccagtc tccacacctc
      241 ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggtttag tggcagtggg
      301 tcagacactg atttcacact gaaaatcagc agggtggagg ctgaggatgt tggggtttac
      361 tactgcatac agtctctaga gtttccttgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01004629             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:8784:15875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004629
VERSION     KCVT01004629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8784:15875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82154.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc tggcctcctt ctcctgcagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaacatct atttggattg gtacctgcag aggccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004630             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13178:3964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004630
VERSION     KCVT01004630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13178:3964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82155.1"
                     /translation="CQQYDSDPYSF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           94 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcttgg acatgagggt ccccgctcag
       61 ctcctaggac tcctgctgct ctgtctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgagt
      181 cagggcatta gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaagccc
      241 ttgatctatt tcgcatccac tttggaaagt ggcgtcccat caaggttcag cggcagtgga
      301 tctgggacag agttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcaac agtatgacag tgacccgtac agttttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01004631             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18133:4503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004631
VERSION     KCVT01004631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18133:4503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82156.1"
                     /translation="CMQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          117 c          123 g          109 t
ORIGIN      
        1 gcatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttatttctgc atgcaaagtc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004632             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25210:9417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004632
VERSION     KCVT01004632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25210:9417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..300
                     /note="immunoglobulin light chain variable region"
     V_region        6..300
     V_segment       6..263
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <240..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82157.1"
                     /translation="CMQALEFPPTF"
     J_segment       266..300
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>303
                     /gene="IGKC"
BASE COUNT           74 a           71 c           86 g           72 t
ORIGIN      
        1 acatgggaga gccggcctcc atctcctgca ggtctagtca gagcctcttg gatagtgggg
       61 atggaaacac ctatttggaa tggtacctac agaagccagg ccagtctcca caactcttga
      121 tttatgaggt ttccaaccgg gcctctggag tcccagacag gttcagtggc agtgggtcag
      181 acactgattt cacactgaaa atcaaccgag tggaggctga ggatgttggg ttttattatt
      241 gcatgcaagc tctagagttt cctcccactt tcggcggagg gaccaaggtg gagatcaaac
      301 gag
//
LOCUS       KCVT01004633             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21170:12894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004633
VERSION     KCVT01004633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21170:12894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82158.1"
                     /translation="CLQYRSYPYNF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          112 c          108 g           97 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag
      181 tcaggatatt agcagttatt taaattggtt tcagaagaaa ccagggaaag cccctaagct
      241 cctgatccaa gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtatagaa gttacccgta caattttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01004634             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17291:12710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004634
VERSION     KCVT01004634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17291:12710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82159.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          119 c          112 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atctcttgcc gggcgagtca
      181 ggacattcgc agttatttag cgtggtatca gcagagacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004635             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:3685:15296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004635
VERSION     KCVT01004635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3685:15296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..395
                     /note="immunoglobulin light chain variable region"
     V_region        74..395
     V_segment       74..357
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82160.1"
                     /translation="CEQYNSLPYTF"
     J_segment       358..395
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>398
                     /gene="IGKC"
BASE COUNT          104 a          104 c           95 g           95 t
ORIGIN      
        1 acatgggatg gacatgaggg tccccgctca gctcctgggg ctcctgctgc tctggctccc
       61 aggtgccaga tgtgacattc agatgaccca gtctccatcc tccctgtctg cttctgtagg
      121 agacagagtc accatcactt gccgggcaag tcaggacatt aacatttatt taaattggta
      181 tcaccagaaa ccggggaaag cccctaagct cctgatctat tatacaaacc gtttggaaag
      241 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      301 cagcctgcaa cctgaagatt ttgcaactta ttactgtgaa caatacaata gtttaccgta
      361 cacttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01004636             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12421:17211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004636
VERSION     KCVT01004636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12421:17211"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82161.1"
                     /translation="CQQYNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattaccaat gatttagcct ggtatcagca gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagtat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004637             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:3052:11304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004637
VERSION     KCVT01004637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:3052:11304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82162.1"
                     /translation="CMQALDFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          102 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagtct
      181 cttggatagt gaggatggaa acacttactt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccga ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga ctttccgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01004638             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24459:12817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004638
VERSION     KCVT01004638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24459:12817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82163.1"
                     /translation="CQQGYRYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtgggagaca cagtcacgat cacttgccag gcgagtcaag
      181 acattgacat taatttaaat tactatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atcccgtttg caaagtggga ttccctctcg attcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatcgttac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004639             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:5929:7351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004639
VERSION     KCVT01004639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:5929:7351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82164.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctccc catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01004640             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24359:4886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004640
VERSION     KCVT01004640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24359:4886"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82165.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          113 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgagga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004641             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:27288:11401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004641
VERSION     KCVT01004641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:27288:11401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..369
                     /note="immunoglobulin light chain variable region"
     V_region        110..369
     V_segment       110..331
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <309..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82166.1"
                     /translation="CMQPLEFPWTF"
     J_segment       332..369
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>372
                     /gene="IGKC"
BASE COUNT           88 a           89 c          105 g           90 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ttagtgggga cattgtgatg accctcttgg
      121 atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc cagtctccac
      181 agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca
      241 gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg
      301 tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg accaaggtgg
      361 aaatcaaacg ag
//
LOCUS       KCVT01004642             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22538:14570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004642
VERSION     KCVT01004642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22538:14570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82167.1"
                     /translation="CMQSLEFPFTF"
     J_segment       403..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          128 c          112 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagga ccggcctcca tctcctgcag gtcaagtcag
      181 agcctcttgg atagtgagga tgaaaacacc tatttggaat ggtacatgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaca tcagcagagt ggagcctgag
      361 gatcttgggg tttactactg catgcaatct ctagagtttc ccttcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01004643             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9487:17420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004643
VERSION     KCVT01004643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9487:17420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82168.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          120 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggttac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgaaga tggaaacacc tatttggagt ggtatctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01004644             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14878:12271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004644
VERSION     KCVT01004644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14878:12271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82169.1"
                     /translation="CLQYKSFPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          105 g          102 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatgggca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccgtcttccc tgtctgcatc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gctattgaca gttatttaaa ttggtttcag cagaaaccag ggaaagcccc taaactcctg
      241 atctattctg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcaccagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaagttt cccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004645             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15656:11551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004645
VERSION     KCVT01004645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15656:11551"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82170.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          109 c          110 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004646             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16263:3765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004646
VERSION     KCVT01004646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16263:3765"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82171.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccacttttcc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg ctagtgagga tggaaacact tatttggact ggtacctaca gaggccaggc
      241 cagactcccc agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 gtcagaggca gtgggtcaga cactgagttc acactgaaaa tcagcagagt ggaggctgag
      361 gatcttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004647             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12696:3942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004647
VERSION     KCVT01004647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12696:3942"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82172.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          126 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcgcc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcgt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01004648             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23777:12850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004648
VERSION     KCVT01004648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23777:12850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82173.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga ttcagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag tcggcctccg tctcctgcag gtctagtcag
      181 agcctcttcg atagtgagga aggaaacacc tttttggagt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtg tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaagtgg aaatcaaacg ag
//
LOCUS       KCVT01004649             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21563:2890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004649
VERSION     KCVT01004649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21563:2890"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82174.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctctctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004650             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15630:14393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004650
VERSION     KCVT01004650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15630:14393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82175.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          113 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004651             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:15499:21082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004651
VERSION     KCVT01004651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15499:21082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..400
                     /note="immunoglobulin light chain variable region"
     V_region        123..400
     V_segment       123..358
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82176.1"
                     /translation="CQQYDSDSLTF"
     J_segment       363..400
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>403
                     /gene="IGKC"
BASE COUNT          103 a          104 c          108 g           88 t
ORIGIN      
        1 acatggggga agacttatta ataggctagg cacgcttcat gcaggagtca gacccagtca
       61 ggacacagca tggacatgag ggtccccgct cagctcctag gactcctgct gctctgtctc
      121 ccaggagaca gagtcaccat cacttgtcgg gcgactcagg acattcgcag ttatttagcg
      181 tggtatcagc agaaaccagg gaaagccccg aagcccttga tctattacgc gtccactttg
      241 gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc
      301 atcagcagcc tgcagcctga agattttgca acttattact gtcaacagta tgacagtgat
      361 tcgctcactt tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004652             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11642:8157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004652
VERSION     KCVT01004652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11642:8157"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82177.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004653             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:26349:8971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004653
VERSION     KCVT01004653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26349:8971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82178.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg ggggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004654             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21901:18897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004654
VERSION     KCVT01004654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21901:18897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82179.1"
                     /translation="CQHSYGFSYSF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          113 c          105 g          101 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgttggagac agactcacca tcacttgcag ggctagtgag
      181 aacgttaaca actatttgca ttggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg catccacttt gcaaagtgga gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcat catcagcagc ctgcagcctg aagatattgc aacttattac
      361 tgtcagcata gttatggttt ctcatacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004655             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18296:8526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004655
VERSION     KCVT01004655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18296:8526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82180.1"
                     /translation="CMQSLDFPLTF"
     J_segment       404..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtt atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggagactg
      361 aggatgttgg ggtttattac tgcatgcagt ctctagattt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaat cgag
//
LOCUS       KCVT01004656             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18648:3857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004656
VERSION     KCVT01004656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18648:3857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82181.1"
                     /translation="CQQHNGNPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           89 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggaaa ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004657             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19514:16931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004657
VERSION     KCVT01004657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19514:16931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82182.1"
                     /translation="CQQYTNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga caaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga gagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatagt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag tatactaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004658             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10133:15491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004658
VERSION     KCVT01004658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10133:15491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82183.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          114 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcaa aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcaaagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004659             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18731:11270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004659
VERSION     KCVT01004659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18731:11270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82184.1"
                     /translation="CQQDFDWPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          127 c          114 g           88 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ctccagcaca
       61 gcttctcttc ctcctgctac tctggatccc agataccacc ggagaagttg tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg ggaaagaccc accctctcct gcagggccag
      181 tcagagtgtt ggcaacacct taacctggta ccagcacaaa cctgggcagg ctcccaagct
      241 cctcctctat ggtgcatcca ccagggcctc cggcatccca ggcaggttca gtgccagtgg
      301 gtctggaaca gagtttactc tcaccatcag cagcctggag cctgaagatg ttggaattta
      361 ttactgtcag caggattttg actggcctcc gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01004660             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18392:14965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004660
VERSION     KCVT01004660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18392:14965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82185.1"
                     /translation="CMQSLEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           93 a          117 c          123 g          110 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttgggga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatgttgagg atggaaacac ctatttggac tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa atcagtagag tggaggctga
      361 ggatgttggg ttttatttct gcatgcaaag tctggagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004661             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20357:19112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004661
VERSION     KCVT01004661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20357:19112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..396
                     /note="immunoglobulin light chain variable region"
     V_region        75..396
     V_segment       75..358
                     /gene="IGKV1-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <336..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82186.1"
                     /translation="CQKCDTVPWTF"
     J_segment       359..396
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>399
                     /gene="IGKC"
BASE COUNT           94 a          106 c          102 g           97 t
ORIGIN      
        1 acatggggat ggacatgagg gcttcagctc agctcctggg actcctgttg ctctggctcc
       61 caggtgccag atgtgccatc cagatgaccc agtctccatc ctccctgtct gcatctgtag
      121 gagacaaagt caccatcact tgccgggcga gtcagagcgt tggtaatagt ttagcctggt
      181 atcagcagaa accagggaaa gttcctaagc tcctgatcta tgctgcatcc actttagaat
      241 cagacgtccc atctcgattc agcggcagtg gatctgggac atatttcact ctcaccatca
      301 gcagtctgtt acctgaggat gttgcgactt attactgtca aaagtgtgac actgtcccgt
      361 ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004662             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23748:8445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004662
VERSION     KCVT01004662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23748:8445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82187.1"
                     /translation="CQQYNSLPYIF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          112 a          110 c          107 g           98 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag
      121 tctccatcct ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt
      181 caggacatta acgtttattt aaattggtat cagcagaaac cggggaaagc ccctaaaccc
      241 ctgatctatt atagaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat
      361 tactgtcaac agtataatag tttaccgtac atttttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01004663             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18244:6014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004663
VERSION     KCVT01004663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18244:6014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82188.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          124 c          120 g          103 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagcggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga accggcctcc atctcctgca ggtctagtca
      181 gagcctcttc gatagtgagg aaggaaccac ctttttggaa tggtacctgc agaggccagg
      241 ccagtctcca cacctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag ttgaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccacggtg gaaatcaaac gag
//
LOCUS       KCVT01004664             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18065:14306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004664
VERSION     KCVT01004664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18065:14306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82189.1"
                     /translation="CQHGYGIPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagtccca gtcaggacac agcatggaca tgagggcccc cactcagctc
       61 ctggggttcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccaatct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcca ggcgagtcag
      181 gccattagta ataatttagt ctggtatcag cagcaaccgg ggaaagcccc taagctcctg
      241 atctataagg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcagcatg gttatggtat cccgtggacg ttcggccaag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004665             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19340:13717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004665
VERSION     KCVT01004665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19340:13717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..409
                     /note="immunoglobulin light chain variable region"
     V_region        95..409
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82190.1"
                     /translation="CQQYNTLPLTF"
     J_segment       379..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctgactcc caggtgccag atgtgacact cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcagcagaa accggggaaa gcccctgagc tcctgatcta
      241 ttatgcaaac cgtttggaaa ctggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgaggac tttgcaactt attactgtca
      361 acagtataat actttaccgc tcactttcgg cggagggacc aaggtggagg tcagacgag
//
LOCUS       KCVT01004666             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15267:4107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004666
VERSION     KCVT01004666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15267:4107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82191.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcaa gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004667             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20152:12455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004667
VERSION     KCVT01004667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20152:12455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82192.1"
                     /translation="CLQYKSYPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          115 c          105 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacaacat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagtagttct ttacattggt ttcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcactg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgctactt attactgtct
      361 acagtataaa agttacccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004668             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14196:19123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004668
VERSION     KCVT01004668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14196:19123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..423
                     /note="immunoglobulin light chain variable region"
     V_region        105..423
     V_segment       105..389
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82193.1"
                     /translation="CQQYNSLPRTF"
     J_segment       391..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>429
                     /gene="IGKC"
BASE COUNT          109 a          111 c          113 g           96 t
ORIGIN      
        1 acatggggag gaggagtcag acccagtcag gacacagcat ggacatgagg gtccccgctc
       61 agctcctggg gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc
      121 agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa
      181 gtcagggcat tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaagg
      241 tcctcatcta ttatgttaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg
      301 gatctgggac agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt
      361 attactgtca acagtataat agtttacctc ggacgttcgg ccaagggacc aaggtggaaa
      421 tcagacgag
//
LOCUS       KCVT01004669             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:5157:14566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004669
VERSION     KCVT01004669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:5157:14566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82194.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatgtca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcaccttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01004670             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21054:5138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004670
VERSION     KCVT01004670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21054:5138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82195.1"
                     /translation="CQQYHSLPWTF"
     J_segment       384..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>424
                     /gene="IGKC"
BASE COUNT          106 a          113 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagta gttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taacctcctg
      241 atctattata caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc aacttattac
      361 tgtcaacagt atcacagttt accgtggacg ttcggccaag ggaccaaggt ggatgtcaaa
      421 cgag
//
LOCUS       KCVT01004671             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14092:12517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004671
VERSION     KCVT01004671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14092:12517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82196.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          128 c          111 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacagacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcgctg ccagtgggtc
      301 tggaacagac tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004672             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23709:11216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004672
VERSION     KCVT01004672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23709:11216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82197.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgacgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggatcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctaactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004673             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10538:18817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004673
VERSION     KCVT01004673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10538:18817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82198.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01004674             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22189:3509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004674
VERSION     KCVT01004674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22189:3509"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82199.1"
                     /translation="CLQYYTIPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          103 g          100 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatct gcaggagaca gagtcaccat cacttgcagg gcaagtcagg
      181 gcattaggac tcatttaaat tggtatcagc agaaaccagg aaaaggtcct aagcgcctga
      241 tctatgctgc atccagtttg gagagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttatttct
      361 gtctacagta ttatactatc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004675             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25958:15326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004675
VERSION     KCVT01004675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25958:15326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..420
                     /note="immunoglobulin light chain variable region"
     V_region        104..420
     V_segment       104..388
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82200.1"
                     /translation="CQQDYSWPLTF"
     J_segment       389..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>428
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g           90 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ctccagcaca
       61 gcttctcttc ctcctgctac tctggatccc agataccacc ggagaagtag taatgacgca
      121 gtctccagcc accctgtctt tgtctccagg ggaacgagcc accctctcct gcagggccag
      181 tcagagtatt ggcagcacct tagcctggta ccagcagaaa cctgggcagg ctcccaagct
      241 cctcatcttt ggtgcatcca gcagggccac cgacatccca gacaggttca gtggcagtgg
      301 gtctggaaca gaatttactc tcaccatcag cagcctggag tctgtagatg ttggagttta
      361 ttactgtcag caggattata gctggcctct cactttcggc ggagggacca aggtggagat
      421 gagacgag
//
LOCUS       KCVT01004676             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22955:7829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004676
VERSION     KCVT01004676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22955:7829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82201.1"
                     /translation="CQQHDNSPPTF"
     J_segment       392..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          105 a          120 c          115 g           89 t
ORIGIN      
        1 acatgggggg caggagtcag tctcagacag gacacagcat ggacacgagg gtccccgctc
       61 agctcctggg gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc
      121 agtctccatc ctccctctct gcatctgtag gagacagagt caccatcact tgcagagcca
      181 gtcagggtgt tagcgactgg ttggcctggt atcaacagag accagggaaa gcccctaaac
      241 tcctgatcta tagggcgtcc aatttggata caggggtccc atcaaggttc agtggaagtg
      301 gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat atcgctacat
      361 attactgtca acagcatgat aattcccctc cgacgttcgg ccaagggacc aaggtggaga
      421 tcaaacgag
//
LOCUS       KCVT01004677             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13054:18229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004677
VERSION     KCVT01004677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13054:18229"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82202.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          116 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctcctt gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttgaagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgctggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004678             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20706:9352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004678
VERSION     KCVT01004678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20706:9352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82203.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccagggca
      241 gtctccacaa ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggactttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01004679             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9226:8972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004679
VERSION     KCVT01004679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9226:8972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82204.1"
                     /translation="CQQDYTWPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          121 c          115 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga tatcaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcaccttaa cctggtatca gcagaaacct gggcaggctc ccaagctcct
      241 catctatcgt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gagtttatta
      361 ctgtcagcag gattatacct ggccgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004680             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16788:9664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004680
VERSION     KCVT01004680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16788:9664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82205.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctactgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004681             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12105:11644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004681
VERSION     KCVT01004681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12105:11644"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82206.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          123 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcagc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004682             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12186:9337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004682
VERSION     KCVT01004682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12186:9337"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82207.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 accctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004683             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17344:7149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004683
VERSION     KCVT01004683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17344:7149"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82208.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctttcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004684             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18032:15770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004684
VERSION     KCVT01004684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18032:15770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82209.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004685             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22090:5339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004685
VERSION     KCVT01004685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22090:5339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82210.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          123 c          114 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcaacag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004686             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12865:14912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004686
VERSION     KCVT01004686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12865:14912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82211.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatacggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004687             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20203:10514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004687
VERSION     KCVT01004687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20203:10514"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82212.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          117 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcgtttatgg tgcatccacc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagac tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004688             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22327:15226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004688
VERSION     KCVT01004688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22327:15226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82213.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagtgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004689             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16781:18873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004689
VERSION     KCVT01004689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16781:18873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82214.1"
                     /translation="CLQGYSPPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          117 c          110 g           97 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gaaaaagccc tgagcgcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa ggttcggcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aggttatttc
      361 tgtctacagg gttatagtcc cccattcact ttcggccccg ggaccaaact ggatttcaaa
      421 cgag
//
LOCUS       KCVT01004690             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:26828:19240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004690
VERSION     KCVT01004690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26828:19240"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82215.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          118 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctgttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagaatgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa ttcaaacgag
//
LOCUS       KCVT01004691             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21358:15688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004691
VERSION     KCVT01004691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21358:15688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82216.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          100 a          125 c          112 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca tcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccagcgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 gcgag
//
LOCUS       KCVT01004692             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:23686:9592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004692
VERSION     KCVT01004692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:23686:9592"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82217.1"
                     /translation="CQQGNSIPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          113 c          105 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gttggagaca gagtcaccat tacttgccgg gcaagtcagg
      181 acattagcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccca aaggtcctga
      241 tctattatgc agacagtttg tcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtatt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004693             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:21922:12818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004693
VERSION     KCVT01004693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21922:12818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82218.1"
                     /translation="CQQGNSNPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcatatg tcccagtctc
      121 cgtcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct gaactcctga
      241 tcttttatac aaacactttg gcaagtgggg tcccatcacg gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtaat ccgttcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004694             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16626:9847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004694
VERSION     KCVT01004694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16626:9847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82219.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg atccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004695             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19149:11787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004695
VERSION     KCVT01004695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19149:11787"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82220.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01004696             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14168:18324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004696
VERSION     KCVT01004696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14168:18324"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82221.1"
                     /translation="CQQYDSDPFSF"
     J_segment       378..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          100 a          111 c          108 g           94 t
ORIGIN      
        1 acatggggag tcaggacaca gcatggacat gagggtcccc gctcagctcc taggactcct
       61 gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc catcctccct
      121 gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg gcattcgcag
      181 ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga tctattacgc
      241 gtccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcagcctga agattttgca acttattact gtcaacagta
      361 tgacagtgac ccgttctctt tcggtggagg gaccaaggta gagatcaaac gag
//
LOCUS       KCVT01004697             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24750:11120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004697
VERSION     KCVT01004697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24750:11120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..366
                     /note="immunoglobulin light chain variable region"
     V_region        89..366
     V_segment       89..324
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82222.1"
                     /translation="CQQYDSDSLTF"
     J_segment       329..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           93 a           96 c          100 g           80 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gagacagagt caccatcact tgtcgggcga
      121 ctcaggacat tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc
      181 ccttgatcta ttacgcgtcc attttggaaa gtggggtccc atcaaggttc agcggcagtg
      241 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      301 attactgtca acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01004698             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18577:13252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004698
VERSION     KCVT01004698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18577:13252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82223.1"
                     /translation="CQQHDDSPRTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          109 a          118 c          106 g           88 t
ORIGIN      
        1 acatggggtc agtctcagac aggacacagc atggacacga gggtccccgc tcagctcctg
       61 gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcacagc cagtcaggat
      181 attaatacct ggttggcctg gtatcaacag aaaccaggaa aagcccctaa actcctgatc
      241 tatagggcat ccaatttgga aacaggggtc ccatcgaggt tcggtggaag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg cagcctgaag atatcgcaac atattactgt
      361 caacagcatg atgattcccc tcggacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01004699             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6612:10199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004699
VERSION     KCVT01004699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6612:10199"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82224.1"
                     /translation="CQQHDNSPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          115 c          113 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgataatt ccccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004700             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:4418:14959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004700
VERSION     KCVT01004700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4418:14959"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82225.1"
                     /translation="CQHGYGIQLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          116 c          113 g           96 t
ORIGIN      
        1 acatgggggg agtcagtccc agtcaggaca cagcatggac atgagggccc ccactcagct
       61 cctggggttc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cagagtcacc atctcttgcc aggcgagtca
      181 ggacattagc aatgatttag cctggtatca gcagaaaccg ggaaaagccc ctaggctcct
      241 gatgtataag gcatccgctt tgcagattgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcaacag cctgcagcct gaagattttg caacttacta
      361 ctgtcaacat ggttatggta tccagctcac tttcggtgga gggaccaagg tggacatcaa
      421 acgag
//
LOCUS       KCVT01004701             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22027:11455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004701
VERSION     KCVT01004701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22027:11455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82226.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacccgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004702             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23083:5085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004702
VERSION     KCVT01004702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23083:5085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82227.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca ggtcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttt ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004703             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14552:11711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004703
VERSION     KCVT01004703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14552:11711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82228.1"
                     /translation="CGQGTHLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          125 c          115 g           94 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 atacacacca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggc
      361 gtttattact gcgggcaagg tacacacctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01004704             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12559:3585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004704
VERSION     KCVT01004704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12559:3585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82229.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccagccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004705             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22855:11598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004705
VERSION     KCVT01004705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22855:11598"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..383
                     /note="immunoglobulin light chain variable region"
     V_region        64..383
     V_segment       64..347
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82230.1"
                     /translation="CLQFKSYPNSF"
     J_segment       350..383
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>388
                     /gene="IGKC"
BASE COUNT           88 a          108 c           97 g           95 t
ORIGIN      
        1 acatgggggg cccccgctca tctcctaggg ctcctgctgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgactca gtctccatct tccctgtctg catctgtagg agacactgtc
      121 accatcactt gccgggcaag tcagggtatt agcagttctt taagttggtt tcagcagaaa
      181 ccagggaaag cccctaagct cctcatctat gctgcatcca ctttggccgg tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcaactta ttactgtcta cagtttaaaa gttacccgaa cagttttggc
      361 caggggacca aagtggagat caagcgag
//
LOCUS       KCVT01004706             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13907:9698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004706
VERSION     KCVT01004706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13907:9698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82231.1"
                     /translation="CQRYSYSTWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          121 c          111 g           91 t
ORIGIN      
        1 acatgggaga gctgctcagt taggacccag agagaaccat ggaaatccca gctcagcttc
       61 tcttcctcct gctactgtgg ctcccaggta ccaccggaca agttatattg actcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 atattggcag cagcttagtt tggtaccagc agaaacctgg gcaggccccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtgcc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agattttgca gtgtattact
      361 gtcagaggta tagttactcc acgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004707             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11521:9715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004707
VERSION     KCVT01004707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11521:9715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82232.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggagcctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004708             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12932:2529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004708
VERSION     KCVT01004708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12932:2529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82233.1"
                     /translation="CIQALEFPWTF"
     J_segment       282..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           74 a           82 c           87 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccac aactcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcaacagagt ggaggctgag
      241 gatgttgggg tttattactg cattcaagct ctagagtttc cgtggacgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004709             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19126:2586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004709
VERSION     KCVT01004709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19126:2586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82234.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          109 c          112 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattgagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcgttaacg tttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagcccctg
      241 atcttttatg caaaccgttt ggaacgtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aagttattat
      361 tgtcaacagt ataatagttt gccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004710             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16596:8634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004710
VERSION     KCVT01004710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16596:8634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82235.1"
                     /translation="CQQHDNSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          120 c          107 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagccac
      181 gatataaata tctggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct
      301 gggacagatt tcaccctcac catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgataattc ccctcggacg ttcggccaag ggaccaaggt ggaagtcaaa
      421 cgag
//
LOCUS       KCVT01004711             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16419:9205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004711
VERSION     KCVT01004711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16419:9205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82236.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cataagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga ggcccctgat
      241 gtattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagcat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004712             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9634:23864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004712
VERSION     KCVT01004712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9634:23864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82237.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 atggggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt ttgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 cagggtggaa atcaaacgag
//
LOCUS       KCVT01004713             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16441:4235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004713
VERSION     KCVT01004713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16441:4235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..265
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82238.1"
                     /translation="CIQSLEFPWTF"
     J_segment       266..302
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           72 a           68 c           89 g           76 t
ORIGIN      
        1 acatggggga gagccggcct ccttctcctg taggtctagt cacagcctct tggatagtga
       61 ggatggaaat atccatttgg attggtatct gcagaagcca ggccagtctc cacacctctt
      121 gatttatgag gtttccaacc gggcctctgg agtcccagac aggtttagtg gcagtgggtc
      181 agacactgat ttcacactga aaatcagcag ggtggaggct gaggatgttg gggtttacta
      241 ctgcatacaa tctctagagt ttccttggac gttcggccag gggaccaagg tggaaatcaa
      301 acgag
//
LOCUS       KCVT01004714             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16918:12384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004714
VERSION     KCVT01004714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16918:12384"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82239.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc agtttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgt tggagggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01004715             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19934:4504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004715
VERSION     KCVT01004715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19934:4504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82240.1"
                     /translation="CQQYFSSPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           91 a          130 c          110 g           93 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttctgtt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttggc ctggtaccac cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagcagt attttagctc cccattcact ttcggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01004716             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18179:19403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004716
VERSION     KCVT01004716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18179:19403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82241.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagaatc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01004717             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:28094:17460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004717
VERSION     KCVT01004717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:28094:17460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82242.1"
                     /translation="CMQYRHIPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          100 a          120 c          115 g          110 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaagct ccctgctcag
       61 ctcctggggc tgctaatgct ctggctctct ggttccagtg gggatgttgt gatgacccag
      121 actccattct ccctgtccgt tagccctgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tgaatagtga agacggaaac acctatttgg attggtacct gcagaggccg
      241 ggccagtctc cacagccctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaattaacag agtggaggct
      361 gaggatgttg ggatttatat ctgcatgcaa tatagacaca ttccattcac tttcggcccc
      421 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01004718             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13478:14558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004718
VERSION     KCVT01004718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13478:14558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    151..352
                     /note="immunoglobulin light chain variable region"
     V_region        151..352
     V_segment       151..314
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <292..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82243.1"
                     /translation="CMQALQTPYSF"
     J_segment       315..352
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>355
                     /gene="IGKC"
BASE COUNT           72 a           96 c          102 g           85 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accttgtcac aatgaggctc cctgctcagc
       61 tcctggggct gctaatgctc tgggtctctg cctccagtgg agatgtcgtg atgacccaga
      121 ctccactctc gctgcccgtc acccttggag ggccagtctc cacatcttct gatctattat
      181 ggttctagtc gggcctccgg ggtccccggc aggttcagtg gcagtgggtc aggcacagat
      241 tttacactga aaatcagcag ggtggaggct gaggacgtag gggtttatta ctgcatgcaa
      301 gctctacaaa ctccgtacag ttttggccag gggaccagag tggagatcaa acgag
//
LOCUS       KCVT01004719             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12354:15389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004719
VERSION     KCVT01004719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12354:15389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82244.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcggcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004720             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23231:9612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004720
VERSION     KCVT01004720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23231:9612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82245.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccctg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaaga ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cctattactg
      361 tcaacagtat gacagtgatc cgttcacttt cggtgggggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01004721             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9655:19683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004721
VERSION     KCVT01004721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9655:19683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82246.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcaaca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004722             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13440:18065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004722
VERSION     KCVT01004722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13440:18065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..383
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82247.1"
                     /translation="CQQGHSYPWTF"
     J_segment       384..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT           99 a          116 c          111 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag tcgagtctag
      181 gcattggcaa atttttaaat tggtatcagc agaaaccagg gaaagccccc aaactcctga
      241 tctatagggc atccagtttg caaactggga ttccctctcg gttcagtggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc gcttattact
      361 gtcaacaggg tcatagttac ccgtggacgt tcggccaagg gaccaaggtg gagatgaaac
      421 gag
//
LOCUS       KCVT01004723             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11944:14957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004723
VERSION     KCVT01004723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11944:14957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82248.1"
                     /translation="CQQGYSYPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          116 c          114 g           96 t
ORIGIN      
        1 acatggggga ggagtcagtc tcagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctccttgggc tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacgcag
      121 tctccctcct ccctgtccgc atctgtagga gacgcagtca cgatcacttg ccaggcgagt
      181 caaggcattg gcaataattt aaattggttt cagcagaaac cagggaaagc ccctaaactc
      241 ctgatctata agacatccag tttgcaaagt gggattccct ctcggttcag cggcagtgga
      301 tctgggacgg atttcactct caccatcagc agcctgcagc ctgaagattt tgccacttat
      361 tactgtcaac agggttatag ttacccgtgg acgttcggcc aaggggccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01004724             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13343:6475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004724
VERSION     KCVT01004724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13343:6475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82249.1"
                     /translation="CHQYDISPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          115 c           99 g           99 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagcat ggacatgagg gtccccactc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga gtcagggcat
      181 taacaattat ttaaattggt atcagcagaa accagggaaa gcccctaagc ccctgatctt
      241 ttatgcatcc actttggaag ccggggtacc atcaaggttc agtggaagtg gatctgggac
      301 agattatact ctcaccatca tcagtctgca gcctgaagat attgcaacat attactgtca
      361 tcagtatgat atttccccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01004725             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23723:20359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004725
VERSION     KCVT01004725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23723:20359"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..323
                     /note="immunoglobulin light chain variable region"
     V_region        6..323
     V_segment       6..285
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <263..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82250.1"
                     /translation="CMQALEFPWTF"
     J_segment       286..323
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>326
                     /gene="IGKC"
BASE COUNT           75 a           79 c           95 g           77 t
ORIGIN      
        1 atgggcactc tccctgcccg tcacccttgg agagccggcc tccatgtcct gcaggtctag
       61 tcagagtctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      121 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      181 caggttcagt ggcggtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      241 tgatgatgtt ggggtttatt actgcatgca agctctagag tttccgtgga cgttcggcca
      301 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01004726             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22137:15826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004726
VERSION     KCVT01004726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22137:15826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82251.1"
                     /translation="CMQAREFPFTF"
     J_segment       406..443
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           99 a          127 c          117 g          103 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gattccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttcgatagtg aggaggggaa cacctatttg gaatggtacc tacagaagcc
      241 aggccagtct ccacaactct tgatttatga ggtctccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgct ggggtttatt actgcatgca agctcgagag tttccattca ctttcggccc
      421 cgggaccaaa ctggacatca aacgag
//
LOCUS       KCVT01004727             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20396:6458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004727
VERSION     KCVT01004727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20396:6458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82252.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          112 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagctgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acaatataac agtgacccgt acacttttgg ccaggggacc aaagtagaga tcaaacgag
//
LOCUS       KCVT01004728             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11040:14896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004728
VERSION     KCVT01004728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11040:14896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..460
                     /note="immunoglobulin light chain variable region"
     V_region        142..460
     V_segment       142..425
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <403..>435
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82253.1"
                     /translation="CQHYISSPFTF"
     J_segment       426..460
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>466
                     /gene="IGKC"
BASE COUNT          106 a          140 c          120 g          100 t
ORIGIN      
        1 acatggggag tccagagccc atatcaatgc ctgggtcaga gctctggaga agagctgctc
       61 agttaggacc cagagagaac catggaaatc ccagctcagc ttctcttcct cctgctactg
      121 tggctcccag gtaccaccgg acaagttata ttgactcagt ctccagccac cctgtctttg
      181 tctccagggg agagagccac cctctcctgc agggccagtc agagtgttgg cagcagctta
      241 gcctggtacc agcagaaacc tgggcaggcc cccaggctcc tcatctatgg tacatccagc
      301 agggccactg gcatcccaga caggttcagt ggcagtgggt ctgggacaga gttcactctc
      361 accatcagca gcctggagcc tgaagatttt gcagtgtatt actgtcagca ctatattagc
      421 tccccattca ctttcggccc cgggaccaaa ctggatatca gacgag
//
LOCUS       KCVT01004729             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:3874:17886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004729
VERSION     KCVT01004729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3874:17886"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82254.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          122 c          117 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agaacctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggagcctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagaatt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01004730             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7476:20391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004730
VERSION     KCVT01004730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7476:20391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..412
                     /note="immunoglobulin light chain variable region"
     V_region        98..412
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82255.1"
                     /translation="CQQYNTLPLTF"
     J_segment       382..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>422
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g           94 t
ORIGIN      
        1 acatggggga gagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac actcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacatt tatttaaatt ggtatcagca gaaaccgggg aaagcccctg agctcctgat
      241 ctattatgca aaccgtttgg aaactggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcaacctgag gactttgcaa cttattactg
      361 tcaacagtat aatactttac cgctcacttt cggcggaggg accaaggtgg aggtcagacg
      421 ag
//
LOCUS       KCVT01004731             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:26916:11920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004731
VERSION     KCVT01004731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26916:11920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82256.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01004732             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22272:9500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004732
VERSION     KCVT01004732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22272:9500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82257.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaac ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004733             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12097:15342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004733
VERSION     KCVT01004733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12097:15342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82258.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          120 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004734             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13892:5000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004734
VERSION     KCVT01004734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13892:5000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..411
                     /note="immunoglobulin light chain variable region"
     V_region        102..411
     V_segment       102..380
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82259.1"
                     /translation="CQQGNSF"
     J_segment       381..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           98 a          112 c          112 g           92 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag ctgtcccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggccattgg taattattta aattggtatc agcagacacc ggggaaagcc cctaagcccc
      241 tgatctatcg tgcaaccggt ttgtcaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga ttttactctc accatcaaca gcctgcagcc tgaagattct gcaacatttt
      361 actgtcaaca gggtaatagt ttcggcggag ggacaaaggt ggcgatcaaa cgag
//
LOCUS       KCVT01004735             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17820:24847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004735
VERSION     KCVT01004735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17820:24847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82260.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgtgtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004736             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:23693:12075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004736
VERSION     KCVT01004736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23693:12075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..400
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82261.1"
                     /translation="CQQYDSDPRTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          106 a          123 c          119 g           93 t
ORIGIN      
        1 acatggggag gcacgcttca tgcaggagtc agacccagtc aggacacagc atggacatga
       61 gggtccccgc tcagctccta ggactcctgc tgctctgtct cccaggcgcc aaatgtgaca
      121 tccagatgac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
      181 cttgtcgggc gagtcagggc attcgcagtt atttagcgtg gtatcagcag aaaccaggga
      241 aagccccgaa gcccttgatc tattacgcgt ccactttgga aagtggggtc ccatcaaggt
      301 tcagcggcag tggatctggg acagagttca ctctcaccat cagcagcctg cagcctgaag
      361 attttgcaac ttattactgt caacagtatg acagtgaccc gcgcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004737             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:25591:20257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004737
VERSION     KCVT01004737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25591:20257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..437
                     /note="immunoglobulin light chain variable region"
     V_region        116..437
     V_segment       116..400
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82262.1"
                     /translation="CQQNSNWPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          127 c          123 g           90 t
ORIGIN      
        1 acatgggggt cagagctctg gggaggaact gctcagttag gacccagagg gaaccatgga
       61 agccccagca cagcttctct tcctcctgct gctctggctc ccagatacca ccggagaaat
      121 agtgttgacg cagtctccag ccaccctgtc tttgtctcca ggagaaagag ccaccctctc
      181 ctgtggggcc agtcagagtg tcagcagcag cttagcctgg taccagcaga aacctgggca
      241 ggctcccaga ctcctcatct atggtgcatc caacagggcc actggcatcc caggcaggtt
      301 ccgtggcagt gggtctggga cagagttcac tctcaccatc agcagcctgg agcctgaaga
      361 tgttgcactt tattattgtc agcagaacag taactggcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004738             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19824:14177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004738
VERSION     KCVT01004738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19824:14177"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82263.1"
                     /translation="CEQYNSLPYTF"
     J_segment       307..344
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           96 a           89 c           78 g           84 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct ccctgtctgc
       61 ttctgtggga gacagagtca ccatcacttg ccgggcaagt caggacatta acatttattt
      121 aaattggtat caccagaaac cggggaaagc ccctaagctc ctgatctatt atacaaaccg
      181 tttggaaact ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcagc agcctgcaac ctgaagattt tgcaacttat tactgtgaac aatacaatag
      301 tttaccgtac acttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01004739             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23422:17902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004739
VERSION     KCVT01004739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23422:17902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82264.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctttgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcaaca gaatagtaac tggcctctca ctttcggtgg agggaccgag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004740             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15700:16405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004740
VERSION     KCVT01004740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15700:16405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82265.1"
                     /translation="CLQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc ctgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004741             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10615:11373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004741
VERSION     KCVT01004741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10615:11373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..373
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82266.1"
                     /translation="CQQGYYTPFTF"
     J_segment       388..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT           98 a          121 c          111 g           98 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgcccga tgtgacatcc agatgaccca
      121 gtctccatcg tccctgtctg catctgtagg agacaaagtc accatctctt gccgagccag
      181 tcagggtatt agcagctggt tagcctggta tcagcagaaa ccagggaaag cccctaaact
      241 cctgatctat aaggcgtcca gtttggcaag tggggtccca tcaaggttca gcggcagtgg
      301 atttgggacg gattacactc tcaccatcag cagcctgcag cctgaagatt ttgctactta
      361 tttttgtcaa cagggttact ataccccatt cactttcggc cccgggacca aactggatat
      421 caatcgag
//
LOCUS       KCVT01004742             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24594:13448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004742
VERSION     KCVT01004742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24594:13448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82267.1"
                     /translation="CMQGTHLPYSF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          121 c          114 g           96 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccactggg gatgttgtca tgactcagtc tccactctcc
      121 ctggccatca cccctggaca accggcctcc atctcctgca ggtctagtta cggccttata
      181 cacagtgatg ggaaaaccta cttgaattgg tatcaccaga agccaggcca acctccaagg
      241 cgcctaatct atcaggtttc taaccgggac tctggggtcc cactcagatt cagcggcagt
      301 ggggcgggga cagatttcac actggaaatc agcagagtgg aggctgaaga tgttggaaat
      361 tattactgca tgcaaggtac acaccttccg tacagttttg gccaggggac cgaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01004743             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18748:14149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004743
VERSION     KCVT01004743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18748:14149"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..355
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82268.1"
                     /translation="SMHDSGGPTTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           95 a          114 c          117 g           92 t
ORIGIN      
        1 acatgggggc tctgagcacc gcctgccagc atgttcttgg gagttcaggt gcagctcctc
       61 tggagcctgg ctttctggag ggcagtgagt ggagacatca tcctgaacca gacgccagca
      121 tccctgactg cacctccagg agagacagtc tccatctcct gccaagccag agcagatgta
      181 catggtgaaa tgtcttggat ccggataaac cttgaacaaa gacttgaacc ccttttatct
      241 catgtcacta ccttggcccc aggtgtcgca gcccggttca tcagcaaggg gagtggcacc
      301 agttatgttt tcagcatcag tgacctgcag cctggggact ctggggacta ttactccatg
      361 catgactctg gggggccaac cactttcggt ggagggacca aggtggagat caaacgaa
//
LOCUS       KCVT01004744             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13901:16541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004744
VERSION     KCVT01004744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13901:16541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82269.1"
                     /translation="CQQYSGLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          113 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag gtatttaaat tggtatcagc agaaaccggg gaaagcccct aagctgctaa
      241 tcttttatgc aaaccgtttg gaaagtgcgg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tggaagccga agatactgca acttattact
      361 gtcagcagta tagtggttta ccgctcactt tcggcggagg gaccaaggtg gagaacaaac
      421 gag
//
LOCUS       KCVT01004745             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8720:17207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004745
VERSION     KCVT01004745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8720:17207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..368
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82270.1"
                     /translation="CQQGYYTPFTF"
     J_segment       383..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT           97 a          121 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg cccgatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat ctcttgccga gccagtcagg
      181 gtattagcag ctggttagcc tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctataaggc gtccagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgct acttattatt
      361 gtcaacaggg ttactatacc ccattcactt tcggccccgg gaccaaactg gatatcaatc
      421 gag
//
LOCUS       KCVT01004746             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17453:8152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004746
VERSION     KCVT01004746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17453:8152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82271.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gtttactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004747             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18931:17623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004747
VERSION     KCVT01004747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18931:17623"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82272.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          117 c          124 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatgtggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004748             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24949:15496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004748
VERSION     KCVT01004748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24949:15496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..331
                     /note="immunoglobulin light chain variable region"
     V_region        10..331
     V_segment       10..289
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82273.1"
                     /translation="CQQYDSDSLTF"
     J_segment       294..331
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           85 a           86 c           86 g           77 t
ORIGIN      
        1 acatggggtg acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac
       61 agagtcacca tcacttgtcg ggcgactcag gacattcgca gttatttagc gtggtatcag
      121 cagaaaccag ggaaagcccc gaagcccttg atctattacg cgtccacttt ggaaagtggg
      181 gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc
      241 ctgcagcctg aagattttgc aacttattac tgtcaacagt atgacagtga ttcgctcact
      301 ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01004749             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13056:16451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004749
VERSION     KCVT01004749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13056:16451"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82274.1"
                     /translation="CMQDIQLPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           84 a          124 c          123 g          106 t
ORIGIN      
        1 catgggggat caggactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 ggggctgctg gtgctctggc tccctgggac cagtggggat attgtgctga ctcagactcc
      121 actctccctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctgcat agtaatggat acacctattt gttttggtac ctgcagaggc caggccagtc
      241 tccacaactt ctggtctatt tgggttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcaggcactg atttcacact gcaaatcagc cgggtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagatataca gcttcctctc actttcggcg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01004750             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13674:2949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004750
VERSION     KCVT01004750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13674:2949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82275.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          121 c          115 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cattggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg ttcctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004751             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13830:9884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004751
VERSION     KCVT01004751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13830:9884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82276.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcttggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctatttcgc atccactttg gaaagtggcg tccgatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004752             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18500:8257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004752
VERSION     KCVT01004752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18500:8257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82277.1"
                     /translation="CLQYKSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          116 c          107 g          100 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg cccgatgtga catccagatg actcagtctc
      121 catcttccct gtctgcttct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 gtcttagcag ttctttacat tggtttcaac acaaaccagg gaaagcccct aggctcctga
      241 tctatgctgc atccagtttg gcaggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagaagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagttac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004753             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9295:8778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004753
VERSION     KCVT01004753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9295:8778"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82278.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgtag tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01004754             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:11198:19026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004754
VERSION     KCVT01004754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11198:19026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82279.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcattccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004755             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21549:13821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004755
VERSION     KCVT01004755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21549:13821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..294
                     /note="immunoglobulin light chain variable region"
     V_region        9..294
     V_segment       9..257
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82280.1"
                     /translation="CQQHDDSPRTF"
     J_segment       259..294
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>297
                     /gene="IGKC"
BASE COUNT           88 a           72 c           75 g           62 t
ORIGIN      
        1 acatgggggc atctgtagga gacagagtca ccatcacttg cacagccagt caggatatta
       61 ataactggtt ggcctggtat caacagaaac caggaaaagc ccctaaactc ctgatctata
      121 gggcatccaa tttggaaaca ggggtcccat cgaggttcgg tggaagtgga tctgggacag
      181 atttcactct caccattagc agcctgcagc ctgaagatat cgcaacatat tactgtcaac
      241 agcatgatga ttcccctcgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01004756             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14311:15674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004756
VERSION     KCVT01004756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14311:15674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82281.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cactggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004757             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12884:6454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004757
VERSION     KCVT01004757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12884:6454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..467
                     /note="immunoglobulin light chain variable region"
     V_region        128..467
     V_segment       128..429
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <407..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82282.1"
                     /translation="CMQPLEFPWTF"
     J_segment       430..467
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>470
                     /gene="IGKC"
BASE COUNT          108 a          128 c          123 g          111 t
ORIGIN      
        1 acatggggac aagcttagca ctaaccttgc cttgactgat cacgactcct caggtcacct
       61 tctcacaatg aggctccctg ctcagctcct gggactgcta atgctctggc tccctggatc
      121 cagtggggac attgtgatga cccagactcc actctccctg tccgtcaccc ttggagagcc
      181 ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg gaaacaccta
      241 tttggaatgg tacctacaga agccaggcca gtctccacag ctcttgattt atgaagtttc
      301 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac
      361 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca tgcaacctct
      421 agagtttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004758             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:27122:9919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004758
VERSION     KCVT01004758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:27122:9919"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82283.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004759             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7944:11082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004759
VERSION     KCVT01004759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7944:11082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82284.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01004760             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23859:18237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004760
VERSION     KCVT01004760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23859:18237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82285.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc aagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004761             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18418:5877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004761
VERSION     KCVT01004761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18418:5877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..433
                     /note="immunoglobulin light chain variable region"
     V_region        98..433
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82286.1"
                     /translation="CMQALEFPRTF"
     J_segment       402..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>440
                     /gene="IGKC"
BASE COUNT           95 a          124 c          117 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgtatc cagtggtgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgcggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt ggctcagaca ctgatttcac actgaaaatc agcagagtgg aggctgaaga
      361 tgttcggatt tattactgca tgcaagctct agagtttcct cggacgttcg gccaggggac
      421 caaggtggaa atcgaacgag
//
LOCUS       KCVT01004762             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10184:4493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004762
VERSION     KCVT01004762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10184:4493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82287.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004763             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18020:11235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004763
VERSION     KCVT01004763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18020:11235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82288.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          122 c          119 g           87 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg ctcccaggct
      241 cctcatcttt ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcagttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01004764             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22049:17548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004764
VERSION     KCVT01004764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22049:17548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82289.1"
                     /translation="CQQGYSFPLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           93 a          119 c          109 g           99 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagttgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcgccatcac ttgccaggcg agtcagggca
      181 ttgccaataa tttatattgg tatcagcaga aaccagggaa agcccctaga ctcctcatct
      241 ataggtcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcag tctcaccatc agcagcctgc agcctgaaga tttcgcctct tattactgtc
      361 aacagggtta tagtttcccg ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004765             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10462:5889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004765
VERSION     KCVT01004765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10462:5889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82290.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctttgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcgtctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01004766             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20124:11380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004766
VERSION     KCVT01004766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20124:11380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82291.1"
                     /translation="CQQHDNSPPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagtctc agacagggca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccttcctcc ctgtctgcat ctataggcga cagagtcacc atcacttgca gagccagtca
      181 gggtattagc gactggttgg cctggtatca acagaaacca gggaaagccc ctaaactcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcaggct gaagatttcg caacatattt
      361 ctgtcaacag catgataatt cccctcccac tttcggtgga gggactaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004767             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18245:9932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004767
VERSION     KCVT01004767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18245:9932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82292.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          111 c           99 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccggacaa gtcaggatat
      181 tcacatttat ttgaattggt ttcagcagaa accagggaaa gcccctaaac tcctgatctc
      241 tgctgcatcc agtttggaaa gtgggttccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcaactt attattgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01004768             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8576:3348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004768
VERSION     KCVT01004768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8576:3348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82293.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004769             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9477:11748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004769
VERSION     KCVT01004769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9477:11748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82294.1"
                     /translation="CQQYYSTPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          104 a          112 c          122 g          101 t
ORIGIN      
        1 acatgggggc tacaacaggc aggcaggggc agcaagatgg tgtcacagac ccaagtcttc
       61 atttccctgt tgctctggat ctctggtgcc tgtggggaca ttgtgatgac ccagtcgcca
      121 gactccctgg ctgtgtctct gggagagagg gtcaccatca actgcaagtc cagccagagt
      181 cttttacgcg tctccaacaa taggaactac ttagcctggt atcagcagaa accagggcag
      241 gctcctaaat tgctcattta ctgggcatct acccgggaat tcgggatccc taaccgattc
      301 agtggcagtg gatctgggtc agatttcact ctcaccatca gtggcctgca ggctgaagat
      361 gtggcagtgt attactgtca gcagtattat agcactccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004770             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6831:4138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004770
VERSION     KCVT01004770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6831:4138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82295.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004771             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23069:12792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004771
VERSION     KCVT01004771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23069:12792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82296.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004772             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21524:5248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004772
VERSION     KCVT01004772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21524:5248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..445
                     /note="immunoglobulin light chain variable region"
     V_region        103..445
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82297.1"
                     /translation="CMQALEFPPFTF"
     J_segment       408..445
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT           96 a          127 c          117 g          108 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cgcccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatactga ggatggaaac acctatttgg aatggtacct gcagaggcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gcgtttatta ttgcatgcaa gctctagagt ttcctccatt cactttcggc
      421 cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01004773             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9284:17036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004773
VERSION     KCVT01004773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9284:17036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82298.1"
                     /translation="CQQYDSDPLTF"
     J_segment       378..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           92 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag tcccgaagcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtatgaca gtgacccgct cactttcggt ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01004774             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:29317:13209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004774
VERSION     KCVT01004774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:29317:13209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82299.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg tatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004775             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9421:7658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004775
VERSION     KCVT01004775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9421:7658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82300.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcgacagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004776             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:26957:11842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004776
VERSION     KCVT01004776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26957:11842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82301.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggctc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004777             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12170:20032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004777
VERSION     KCVT01004777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12170:20032"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82302.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004778             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13353:19584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004778
VERSION     KCVT01004778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13353:19584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82303.1"
                     /translation="CLQGYSPPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattta cgattattta agttggtatc agcagaaacc aggaaaagct cctaagcgcc
      241 tgatctatgc tgcatccagt ttgcaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtctaca gggttatagt cccccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004779             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23672:18376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004779
VERSION     KCVT01004779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23672:18376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82304.1"
                     /translation="CQQYNTLPLTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          109 a          109 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatacttta ccattgacgt tcggccaagg gaccaaggtg gaaatcaaag
      421 gag
//
LOCUS       KCVT01004780             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19794:16884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004780
VERSION     KCVT01004780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19794:16884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82305.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          122 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtaccaacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcagacga g
//
LOCUS       KCVT01004781             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:5084:8389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004781
VERSION     KCVT01004781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5084:8389"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82306.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 tttcgcatcc actttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gccgcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc aaagtggaca tcaaacgag
//
LOCUS       KCVT01004782             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20100:1984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004782
VERSION     KCVT01004782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20100:1984"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82307.1"
                     /translation="CLQYKGYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          116 c          108 g           99 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgccc gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcttctgta ggagacactg tcaccatcac ttgccgggca agtcagggtc
      181 ttagcagttc tttacattgg tttcaacaca aaccagggaa agcccctagg ctcctgatct
      241 atgctgcatc cagtttggca ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagagttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtataa aggttacccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004783             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22120:6579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004783
VERSION     KCVT01004783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22120:6579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82308.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           99 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttagag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaggccag
      241 gccagtctcc acagctctta atttatgagg tttcctaccg ggcctctgga gtcccagaga
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaag cgag
//
LOCUS       KCVT01004784             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20989:16010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004784
VERSION     KCVT01004784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20989:16010"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82309.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatattg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggtcagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004785             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:28298:9051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004785
VERSION     KCVT01004785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:28298:9051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82310.1"
                     /translation="CMQALQTPRTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          103 a          118 c          115 g          103 t
ORIGIN      
        1 acatggggag atcagaactg ctcagttcac cttctcaaga tgaagttcca tgctcagctc
       61 ctgggactgt taatgctctg ggtctctgaa tccagtgggg atattgtgat gacccagact
      121 ccactctccc tgcccgtgac ccctggggag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctac atagtaatgg aaatacctat ttgtattggt acctgcagaa gccagggcag
      241 cctccacggc tcctaatcta tacagtttcc acccggttct ctggagtgcc agacaggttc
      301 agtggcagtg gatcaggcac agacttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gtcgggattt attactgcat gcaagcttta cagactcctc ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004786             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9841:16149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004786
VERSION     KCVT01004786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9841:16149"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82311.1"
                     /translation="CYQHSRGWAF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           96 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggga gctgctaggt tagtacccag aaggaaccat ggaagcccca gctcagcttc
       61 tctgccttct gctactctgg ctcccaggca ccaccggaca agttatgttg acacagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccactct ctcctgcagg gccagtgaga
      181 atgttggcat ctacttagcc tggtaccagc agaaccctgg gcaggctccc aggctcctca
      241 tccacagtgc gtccagcagg gccactgaca tcccagacag gttcagtggc agtgggtctc
      301 ggacagagtt caccctcacc atcagcagcc tggagcctga agatgttgga gtctattact
      361 gctatcaaca tagcaggggg tgggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004787             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8560:3608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004787
VERSION     KCVT01004787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8560:3608"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82312.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acagggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004788             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14263:21732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004788
VERSION     KCVT01004788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14263:21732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82313.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          126 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttggtt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cgctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004789             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15044:6712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004789
VERSION     KCVT01004789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15044:6712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82314.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          118 c          117 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgtatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004790             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18919:5626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004790
VERSION     KCVT01004790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18919:5626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82315.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          116 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagtcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004791             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9495:9172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004791
VERSION     KCVT01004791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9495:9172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..404
                     /note="immunoglobulin light chain variable region"
     V_region        102..404
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82316.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..404
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           86 a          123 c          105 g           90 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cggg
//
LOCUS       KCVT01004792             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12064:18549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004792
VERSION     KCVT01004792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12064:18549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82317.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat tcagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01004793             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22132:15125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004793
VERSION     KCVT01004793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22132:15125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82318.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccggggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004794             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:24417:14497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004794
VERSION     KCVT01004794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24417:14497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82319.1"
                     /translation="CMQGTHLPFTF"
     J_segment       390..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          118 c          110 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtctatca ctcttggaca accggcctcc atttcctgca ggtctagtca cacctttgta
      181 cacagtgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggagtt
      361 tattactgca tgcaaggtac acaccttcca ttcactttcg gccccgggac caaactggat
      421 atcaaacgag
//
LOCUS       KCVT01004795             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5365:10842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004795
VERSION     KCVT01004795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5365:10842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..375
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82320.1"
                     /translation="CQQVYSSPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          114 c          108 g          104 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtct
      121 ccatctgcct tgtctgcatc tgtgggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata gttatttagc gtggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg tatccagatt gcaaagtggg gttccctctc ggttcagcgg cagtggaact
      301 gggacagatt tcactctcag catcagcagc ctacagcctg aagattctgc cggttattac
      361 tgtcaacagg tttatagtag tccattcact ttcggccccg ggaccaaact ggctatcaaa
      421 cgag
//
LOCUS       KCVT01004796             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18871:10750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004796
VERSION     KCVT01004796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18871:10750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82321.1"
                     /translation="CQQYNSEPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          112 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agcgtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga gccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004797             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11829:9988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004797
VERSION     KCVT01004797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11829:9988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82322.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01004798             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:9936:8047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004798
VERSION     KCVT01004798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9936:8047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82323.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc acagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004799             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19746:9939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004799
VERSION     KCVT01004799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19746:9939"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..246
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82324.1"
                     /translation="CLQGYITPYSF"
     J_segment       247..284
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           76 a           67 c           76 g           68 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg ccgggcaagt caggacatta gcgatttttt
       61 aagttggtat cagcagaaac caggaaaacc tcctaagcgc ctgatttatg ctgcatccag
      121 tttgcaaagt ggggtcccgt caaggttcag cggcagtgga tctgggacag aattcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcggcttat tactgtctac agggttatat
      241 taccccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01004800             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6126:12832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004800
VERSION     KCVT01004800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6126:12832"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82325.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg cgtccgcttt ggaaagtggg gtcccatcaa gggtcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01004801             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15777:13095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004801
VERSION     KCVT01004801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15777:13095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82326.1"
                     /translation="CQQGYSYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          118 c          108 g           95 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgca ggagacacag tcaccatcac ttgccaggcg agtcaaggca
      181 ttggcaatac tttaaattgg tatcaacaga aaccggggaa agcccctaca ctcctgatct
      241 atagggcatc cggtttgcaa agtgggactc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttatccg tacagttttg gccaggggac caaactggag atcaaacgag
//
LOCUS       KCVT01004802             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7720:17756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004802
VERSION     KCVT01004802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7720:17756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82327.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtagaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004803             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20854:22396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004803
VERSION     KCVT01004803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20854:22396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..435
                     /note="immunoglobulin light chain variable region"
     V_region        100..435
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82328.1"
                     /translation="CMQYTHMPLTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>442
                     /gene="IGKC"
BASE COUNT           99 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctgga tccagtgggg atactgtgat gacccagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg acagtgaaga tggaaacacc tatttggatt ggtacctgca aaagccgggc
      241 cagtcgccac agcccttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaatat acacacatgc cgctcacttt cggcggaggg
      421 accaaggtgg agatcgaacg ag
//
LOCUS       KCVT01004804             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12882:2595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004804
VERSION     KCVT01004804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12882:2595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82329.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgttgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004805             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14475:14315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004805
VERSION     KCVT01004805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14475:14315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82330.1"
                     /translation="FEQYNSLPYTF"
     J_segment       307..344
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           96 a           88 c           78 g           85 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct ccctgtctgc
       61 ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacgtta acatttattt
      121 aaattggtat caccagaaac cggggaaagc ccctaagctc ctgatctatt atacaaaccg
      181 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcagc agcctgcaac ctgaagattt tgcaacttat tactttgaac aatacaatag
      301 tttaccgtac acttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01004806             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21370:2797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004806
VERSION     KCVT01004806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21370:2797"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82331.1"
                     /translation="CQQYDSDSLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaagat tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgactc gctcactttc ggtggaggga ccaaggtaga gatcaaacga
      421 g
//
LOCUS       KCVT01004807             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:8871:3178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004807
VERSION     KCVT01004807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8871:3178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..362
                     /note="immunoglobulin light chain variable region"
     V_region        82..362
     V_segment       82..322
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82332.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       330..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           98 a           88 c           93 g           86 t
ORIGIN      
        1 acatggggag aaccactcag gacacaggat ggacatgacg gtccccgctt atctcctggg
       61 gctccttctg ctctggctcc caggagacaa agtcaccatc acttgcaggg caagtcagga
      121 cattggtaat tatttaaatt ggtatcagca gaaaccagga aaagctccta aggtccggat
      181 ctatggtgta tccaatttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagatctt actctcacca tcagcagcct gcagcctgaa gattttgcaa cgtattattg
      301 tcaaacgttt aaaagttacc tttcggtccc tttcggcgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01004808             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18860:4628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004808
VERSION     KCVT01004808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18860:4628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82333.1"
                     /translation="CMQSLDFPLTF"
     J_segment       404..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccaatgg ggacattgtt atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgaa gatggaaaca cctatttgga gtggtatctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcagt ctctagattt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaat cgag
//
LOCUS       KCVT01004809             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8234:8012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004809
VERSION     KCVT01004809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8234:8012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82334.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          120 c          124 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004810             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18510:8445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004810
VERSION     KCVT01004810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18510:8445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82335.1"
                     /translation="CQQYNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          120 c          108 g           89 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca gcttattatt
      361 gtcaacagta taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004811             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18198:11463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004811
VERSION     KCVT01004811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18198:11463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    34..319
                     /note="immunoglobulin light chain variable region"
     V_region        34..319
     V_segment       34..281
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82336.1"
                     /translation="CLQSKNSPWSF"
     J_segment       282..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           88 a           82 c           84 g           68 t
ORIGIN      
        1 acatggggag gagcagcctc tagttcagct ctccagaggg ccaccatcac ctgcagagcc
       61 agtgagagtg tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga
      121 caacctccta aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg
      181 ttcagcggca gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac
      241 gatggtgcag attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004812             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12826:15347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004812
VERSION     KCVT01004812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12826:15347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..411
                     /note="immunoglobulin light chain variable region"
     V_region        98..411
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82337.1"
                     /translation="CQQGHSYPWTF"
     J_segment       382..411
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>422
                     /gene="IGKC"
BASE COUNT           98 a          117 c          111 g           96 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcacgatc acttgccagt cgagtctagg
      181 cattggcaaa tttttaaatt ggtatcagca gaaaccaggg aaagccccca aactcctgat
      241 ctatagggca tccagtttgc aaactgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgccg cttattactg
      361 tcaacagggt catagttacc cgtggacgtt cggccaaggg accaaggtgg agatgaaacg
      421 ag
//
LOCUS       KCVT01004813             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17645:17140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004813
VERSION     KCVT01004813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17645:17140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82338.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          120 c          105 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaaca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004814             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18408:22201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004814
VERSION     KCVT01004814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18408:22201"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..290
                     /note="immunoglobulin light chain variable region"
     V_region        16..290
     V_segment       16..248
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82339.1"
                     /translation="CQQYDSDSLTF"
     J_segment       253..290
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>293
                     /gene="IGKC"
BASE COUNT           77 a           72 c           79 g           65 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaccat cacttgtcgg gcgactcagg acattcgcag
       61 ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga tctattacgc
      121 gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      181 cactctcacc atcagcagcc tgcagcctga agattttgca acttattact gtcaacagta
      241 tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004815             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17886:12248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004815
VERSION     KCVT01004815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17886:12248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82340.1"
                     /translation="CQQYNTLPLSF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          111 c          106 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagta attatttaaa ttggtatcaa cagaaaccgg ggaaagcccc taaactcctg
      241 atctattatg caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcgc catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt ataatacttt acctctcagt ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004816             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5887:8298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004816
VERSION     KCVT01004816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5887:8298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82341.1"
                     /translation="CQQYSSYPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          118 c          107 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggatcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acaaagtcac catcacttgc cgagccagtc
      181 agggtattag cagcttgtta gcctggtatc agcagaaacc agggaaagcc cctaagtccc
      241 tgatctataa ggcatccagt ttgcaaagtg gggtcccttc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc agcatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatagtagt tacccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01004817             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17002:10444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004817
VERSION     KCVT01004817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17002:10444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82342.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctgtatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01004818             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18520:16806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004818
VERSION     KCVT01004818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18520:16806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82343.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatactctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004819             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:8771:6478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004819
VERSION     KCVT01004819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8771:6478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82344.1"
                     /translation="CMQPLEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          122 c          119 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg aatccagtgg ggacattgtg atgacccaga
      121 gtccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatactgag gatggaaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattcc tgcatgcaac ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004820             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9279:4844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004820
VERSION     KCVT01004820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9279:4844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82345.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          116 c          110 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattaacaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaggtcctga
      241 tctatagggc atccattttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004821             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22034:18117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004821
VERSION     KCVT01004821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22034:18117"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82346.1"
                     /translation="CQQYNSLPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          105 g          101 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatgt cgaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttatttct
      361 gtcaacagta taatagttta ccattcactt tcggccccgg gaccaaactg gatctcaaac
      421 gag
//
LOCUS       KCVT01004822             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12023:10171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004822
VERSION     KCVT01004822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12023:10171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82347.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          124 c          118 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagaacc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggaag gaaccacctt tttggaatgg tacctgcaga ggccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagttg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 cacggtggaa atcaaacgag
//
LOCUS       KCVT01004823             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14492:17247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004823
VERSION     KCVT01004823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14492:17247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82348.1"
                     /translation="CQQHNNYSPTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccac
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttagcaatga tttagcctgg tatcaactga aaccagggaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagcataa taattactct cccactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004824             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:25149:15009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004824
VERSION     KCVT01004824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25149:15009"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82349.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagac ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004825             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11515:8213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004825
VERSION     KCVT01004825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11515:8213"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..368
                     /note="immunoglobulin light chain variable region"
     V_region        91..368
     V_segment       91..330
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82350.1"
                     /translation="CQQYDSDPRTF"
     J_segment       334..368
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           92 a          100 c          103 g           76 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggagacaga gtcaccatca cttgtcgggc
      121 gagtcagggc attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa
      181 gcccttgatc tattacgcgt ccactttgga aactggggtc ccatcaaggt tcagcggcag
      241 tggatctggg acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac
      301 ttattactgt caacagtatg acagtgaccc gcgcactttc ggtggaggga ccaaggtgga
      361 gatcaaacga g
//
LOCUS       KCVT01004826             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:10282:11093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004826
VERSION     KCVT01004826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10282:11093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..401
                     /note="immunoglobulin light chain variable region"
     V_region        110..401
     V_segment       110..363
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82351.1"
                     /translation="CMQSLELPFTF"
     J_segment       364..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           91 a          107 c          108 g           98 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 catctcctgc aggtctagtc agagcctcgt ggatagtgag gatggaaaca cctatttgga
      181 atggttcctg cagaggccag gccagtctcc acagctcttg atttatgacg tttccaaccg
      241 ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgag
      301 aatcagcaga gtggaggctg aggatgttgg gatttattac tgcatgcaat ctctagagct
      361 tccattcact ttcggccccg ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01004827             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14036:6636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004827
VERSION     KCVT01004827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14036:6636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82352.1"
                     /translation="CQQGHSYPWTF"
     J_segment       379..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          110 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccagtcga gtctaggcat
      181 tggcaaattt ttaaattggt atcagcagaa accagggaaa gcccccaaac tcctgatcta
      241 tagggcatcc agtttgcaaa ctgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccgctt actactgtca
      361 acagggtcat agttacccgt ggacgttcgg ccaagggacc aaggtggaga tgaaacgag
//
LOCUS       KCVT01004828             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17159:3378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004828
VERSION     KCVT01004828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17159:3378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..348
                     /note="immunoglobulin light chain variable region"
     V_region        9..348
     V_segment       9..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82353.1"
                     /translation="CMQALEFPWTF"
     J_segment       312..348
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           81 a           88 c          100 g           82 t
ORIGIN      
        1 acatggggga cattgtgatg acccagactc cagtctccct gcccgtcacc ctgggagagc
       61 cggcctccat ctcctgccgg tctagtcaga gcctcttgga tagtgaggat ggaaacacct
      121 atttggaatg gcacctgcag aggccaggcc agtctccaca gctcttgatt tatgaggttt
      181 cctatcgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      241 cactgaaaat cagcagagtg gaggctgagg atgttggtat ttattactgc atgcaagctc
      301 tagagtttcc ttggacgttc ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004829             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20558:14399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004829
VERSION     KCVT01004829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20558:14399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82354.1"
                     /translation="CQRYSYSTWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          120 c          115 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttggt ttggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtatattac
      361 tgtcagaggt atagttactc cacgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004830             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18292:11925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004830
VERSION     KCVT01004830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18292:11925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82355.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac attgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004831             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17973:3701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004831
VERSION     KCVT01004831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17973:3701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82356.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aagccaggcc
      241 agtctccaca gcttttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004832             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14602:13737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004832
VERSION     KCVT01004832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14602:13737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    171..325
                     /note="immunoglobulin light chain variable region"
     V_region        171..325
     V_segment       171..284
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <267..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82357.1"
                     /translation="CQQSYRYPLTF"
     J_segment       290..325
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>330
                     /gene="IGKC"
BASE COUNT           71 a           93 c           92 g           74 t
ORIGIN      
        1 atggggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg agtggggtcc
      181 catcaaggtt cagcggcagt ggatctggga cagatttcac tctcgccatc agcagcctgc
      241 agcctgaaga tgctgcaact tattactgtc agcagagtta tcgttatccg ctcactttcg
      301 gtggagggac ccaggtggaa atcaatcgag
//
LOCUS       KCVT01004833             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:24620:12043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004833
VERSION     KCVT01004833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24620:12043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    30..351
                     /note="immunoglobulin light chain variable region"
     V_region        30..351
     V_segment       30..314
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82358.1"
                     /translation="CQQYDSFPLSF"
     J_segment       319..351
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>354
                     /gene="IGKC"
BASE COUNT           94 a           91 c           85 g           84 t
ORIGIN      
        1 acatggggga gtcagaccca gccagatgtg acagccagat gacccagtct ccatcctccc
       61 tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag gacatttata
      121 cttttttaaa ttggtatcaa cagagaccgg ggaaagcccc taacctcctg atctattttg
      181 caaaccgttt ggaaagaggg gtcccagcaa ggttcagcgg cagtggatct gggacagaat
      241 tcactctcac catcagcagc ctccaacctg aagattttgc aacttattac tgtcaacaat
      301 atgatagttt tcctctctct ttcggcggag ggaccaaggt ggagagcaaa cgag
//
LOCUS       KCVT01004834             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24711:7025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004834
VERSION     KCVT01004834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24711:7025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..320
                     /note="immunoglobulin light chain variable region"
     V_region        121..320
     V_segment       121..283
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <260..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82359.1"
                     /translation="CMQALEFPWTF"
     J_segment       284..320
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>323
                     /gene="IGKC"
BASE COUNT           73 a           81 c           88 g           81 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctcca cagctcttga tttatgaggt ttcctatcgg gcctctggag tcccagacag
      181 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      241 ggatgttggt atttattact gcatgcaagc tctagagttt ccttggacgt tcggccaagg
      301 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004835             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8713:5987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004835
VERSION     KCVT01004835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8713:5987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82360.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          113 a          112 c          102 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctcagctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004836             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12638:6429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004836
VERSION     KCVT01004836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12638:6429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..250
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82361.1"
                     /translation="CQQHNGYPPTF"
     J_segment       263..297
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           85 a           75 c           74 g           66 t
ORIGIN      
        1 acatggggtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
       61 ttacgaatga tttagcctgg tatcaacaga aaccaggtaa agccccgaag cccctgatct
      121 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      181 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      241 aacaacataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01004837             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19376:10537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004837
VERSION     KCVT01004837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19376:10537"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82362.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004838             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18324:8565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004838
VERSION     KCVT01004838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18324:8565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82363.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          117 c          107 g           87 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagga
      181 tattaacacc tggttggcct ggtatcaaca gaagccaggg aaagccccta aggtcctgat
      241 ctataggaca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcaacagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01004839             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15720:12559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004839
VERSION     KCVT01004839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15720:12559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82364.1"
                     /translation="CMQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct acccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tacaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004840             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12285:9368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004840
VERSION     KCVT01004840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12285:9368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82365.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           99 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtcaagt
      181 cagagcctcc tggatagtga ggatggaaac acctatttgc actggtactt gaagaagcca
      241 ggccagtctc cacagctctt aatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01004841             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:8695:9122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004841
VERSION     KCVT01004841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8695:9122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82366.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt gccagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004842             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19510:11747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004842
VERSION     KCVT01004842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19510:11747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82367.1"
                     /translation="CQQHDNAPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          115 c          114 g           84 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagagta
      181 ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcagcatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 agcagcatga caatgccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004843             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15924:15368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004843
VERSION     KCVT01004843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15924:15368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82368.1"
                     /translation="CQHSYGTPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          114 c          106 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtag gacaagtcag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taggctcctg
      241 atctatgctg cgtccaattt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactttcac catcaccagc ctgcaacctg aagatgttgc aacttattac
      361 tgtcagcata gttatggtac cccgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004844             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14423:18725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004844
VERSION     KCVT01004844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14423:18725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..237
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82369.1"
                     /translation="CMQDIQLPLTF"
     J_segment       238..274
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>277
                     /gene="IGKC"
BASE COUNT           64 a           66 c           79 g           68 t
ORIGIN      
        1 acatgggggt ctagtcagag cctcctgcat agtaatggat acacctattt gttttggtac
       61 ctgcagaagc caggccagtc tccacaactc ctgatctatt tgggttccaa ccgggcctct
      121 ggagtcccag acaggttcag tggcagtggg tcaggcactg atttcacact gcaaatcagc
      181 cgggtggagg ctgaggatgt tggggtttat tactgcatgc aagatataca gcttcctctc
      241 actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01004845             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18826:6602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004845
VERSION     KCVT01004845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18826:6602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82370.1"
                     /translation="CMQSLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          121 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acatcgtgct gacccagact
      121 cctctctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc ccctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004846             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:8069:12572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004846
VERSION     KCVT01004846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8069:12572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..398
                     /note="immunoglobulin light chain variable region"
     V_region        77..398
     V_segment       77..361
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82371.1"
                     /translation="CQQNSNWPLTF"
     J_segment       362..398
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>401
                     /gene="IGKC"
BASE COUNT           95 a          118 c          106 g           82 t
ORIGIN      
        1 acatggggag ggaaccatgg aagccccagc acagcttctc ttcctcctgc tgctctggct
       61 cccagatacc accggagaaa tagtgatgac gcagtctcca gccaccctgt ctttgtctcc
      121 aggagaaaga gccaccctct cctgcagggc cagtcagagt gtcagcagca gcttagcctg
      181 gtaccaacaa aaacctgggc aggctcccag gctcctcatc tatggtgcat ccagcagggc
      241 cactggcatc ccagacaggt tcagtggcag tgggtctggg acagacttca ctctcaccat
      301 caccagcctg gagcctgaag atgttgcagt ttattattgt cagcagaata gtaactggcc
      361 tctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004847             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18676:14474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004847
VERSION     KCVT01004847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18676:14474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82372.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          126 c          121 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaag ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcaac agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01004848             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13307:20594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004848
VERSION     KCVT01004848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13307:20594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82373.1"
                     /translation="CQQDFDWPPAF"
     J_segment       391..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccgg cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004849             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12346:5645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004849
VERSION     KCVT01004849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12346:5645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    151..311
                     /note="immunoglobulin light chain variable region"
     V_region        151..311
     V_segment       151..273
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <251..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82374.1"
                     /translation="CMQALDFPWTF"
     J_segment       274..311
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>314
                     /gene="IGKC"
BASE COUNT           69 a           88 c           84 g           73 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cattggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctctgga gtcccagaca ggttcagtgg
      181 cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      241 gatttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag ggaccaaggt
      301 ggaaatcaaa cgag
//
LOCUS       KCVT01004850             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18279:7947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004850
VERSION     KCVT01004850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18279:7947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..402
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82375.1"
                     /translation="CQQYDSDSLTF"
     J_segment       407..444
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          109 a          122 c          117 g           99 t
ORIGIN      
        1 acatggggga ggctaggcac gcttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca ggtgccaaat
      121 gtgacatcca gatgacccag tccccatcct ccctgtctgc atctgtagga gacagagtca
      181 ccatcacttg tcgggcgact caggacattc gcagttattt agcgtggtat cagcagaaac
      241 cagggaaagc cccgaagccc ttgatctttt acgcgtccac tttggaaaat ggggtcccat
      301 caaggttcag cggcagtgga tctgggacag aattcactct caccattagc agcctgcagc
      361 ctgaagattt tgcaacttat tactgtcaac agtatgacag tgattcgctc actttcggtg
      421 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01004851             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14199:11618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004851
VERSION     KCVT01004851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14199:11618"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82376.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ctcgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01004852             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15439:4659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004852
VERSION     KCVT01004852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15439:4659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82377.1"
                     /translation="CLQGYSAPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          116 c          108 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcttcggtag gagacagagt caccatcatt tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa actcctcagc gcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcggtg ggtctgggac
      301 agaattcact ctcaccgtca gcagcctgct gtctgaagat tttgcagctt attactgtct
      361 ccagggttat agtgccccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01004853             379 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4249:10509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004853
VERSION     KCVT01004853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 379)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4249:10509"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    55..376
                     /note="immunoglobulin light chain variable region"
     V_region        55..376
     V_segment       55..338
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <316..>348
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82378.1"
                     /translation="CQQYNSLPFSF"
     J_segment       345..376
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        377..>379
                     /gene="IGKC"
BASE COUNT           97 a           94 c           99 g           89 t
ORIGIN      
        1 acatgggggg caggagtcag acccagtcag ctctggctcc caggtgccag atgtgacatt
       61 cagatgaccc agtctccatc ctccctgtct gcatctgtag gggacagagt caccatcact
      121 tgccgggcaa gtcaggacat tagtagtttt ttaaattggt atcagcagaa accggggaaa
      181 gcccctcagc tcctgatcta ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc
      241 agcggcagtg gatctgggac agaattcact ctcaccatca gcagcctgca acctgaggat
      301 tttgcaactt atcactgtca acagtataat agtttaccgt tcagtttcgg tggagggacc
      361 aaggtggaga tcaaacgag
//
LOCUS       KCVT01004854             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:23751:5156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004854
VERSION     KCVT01004854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23751:5156"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82379.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcttcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaaaccaggc
      241 cagtctccac gactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004855             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12642:19260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004855
VERSION     KCVT01004855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12642:19260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82380.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaata agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004856             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5268:13901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004856
VERSION     KCVT01004856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5268:13901"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82381.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          123 c          115 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattttg atgacccaga
      121 ctccactctc cctgcccgtc agccttggag agccggcctc catgtcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ctggtacctg caaaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaaa gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01004857             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:7403:7727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004857
VERSION     KCVT01004857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7403:7727"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82382.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gtatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004858             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17925:17448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004858
VERSION     KCVT01004858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17925:17448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82383.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          117 c          123 g          109 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacttgc agaaggcagg
      241 ccagtctcca cagctcttga tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag ccactgattt caaactgaac atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004859             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:5354:22601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004859
VERSION     KCVT01004859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:5354:22601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82384.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc caagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01004860             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14281:11200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004860
VERSION     KCVT01004860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14281:11200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..436
                     /note="immunoglobulin light chain variable region"
     V_region        103..436
     V_segment       103..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82385.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           92 a          117 c          126 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agcggggacg tagtgatgac ccagactcca
      121 ctctccctgt ccgtcaccct tggagagtcg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggatg gtgaggatgg aaacacctac ttggaatggt atttgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aagcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gcagagtgga ggctggggat
      361 gttggggttt atcactgcat gcaagctcta gagtttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01004861             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14600:15119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004861
VERSION     KCVT01004861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14600:15119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82386.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004862             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20972:9616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004862
VERSION     KCVT01004862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20972:9616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82387.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          125 c          111 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga cagtgaggat gaaaacacgt atttggaatg gtacgtgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat caacagagtg gaggctgagg
      361 atcttggaat ttattactgc atgcaagctc tagaatttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01004863             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12120:11915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004863
VERSION     KCVT01004863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12120:11915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82388.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          119 c          128 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cctctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acgtagtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag tcggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctggg
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004864             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15370:16996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004864
VERSION     KCVT01004864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15370:16996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..297
                     /note="immunoglobulin light chain variable region"
     V_region        87..297
     V_segment       87..260
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82389.1"
                     /translation="CQQDFGWPPTF"
     J_segment       263..297
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           73 a           81 c           83 g           63 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga aacctgggca gactcacaaa ctcctcattt
      121 atggtgcatc cagcagggcc accggcatcc cagacaggtt cagtggcagt gggtctggaa
      181 cagagttcac tctcaccatc agtagtccgg agcctgagga tgttggagtt tattactgtc
      241 agcaggattt tggctggcct ccgacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004865             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18122:21243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004865
VERSION     KCVT01004865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18122:21243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82390.1"
                     /translation="CLQGDTAPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggcaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gtgatactgc cccgttcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgaa
//
LOCUS       KCVT01004866             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:3733:16164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004866
VERSION     KCVT01004866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3733:16164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82391.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttgggt agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004867             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23936:6744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004867
VERSION     KCVT01004867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23936:6744"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82392.1"
                     /translation="CQQGYSYPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccaggcg agtcaagcca
      181 ttggcaataa tttaaattgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 ctaaggcatc cagtttgcaa agtgggattc cctctcggct cagcggcagt ggatctgggg
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tactactgtc
      361 aacagggtta tagttacccg tggacattcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004868             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15199:8376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004868
VERSION     KCVT01004868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15199:8376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82393.1"
                     /translation="CMQALEFLWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttct gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004869             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13034:21377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004869
VERSION     KCVT01004869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13034:21377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82394.1"
                     /translation="CMQSLDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcaca cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gcttttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggtag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagactttcc gtggacgttc ggcccaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004870             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5888:16715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004870
VERSION     KCVT01004870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5888:16715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82395.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          108 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccacagtg gagattaaac gag
//
LOCUS       KCVT01004871             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7079:13271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004871
VERSION     KCVT01004871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7079:13271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82396.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          117 c          116 g          108 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgaatc cagtggggac attgtgatga cgcagactcc
      121 atactccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctactcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtct cagacaggtt
      301 cagtggcaat gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggttgag atcaaacgag
//
LOCUS       KCVT01004872             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16856:12614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004872
VERSION     KCVT01004872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16856:12614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82397.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          116 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggtctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtgggag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004873             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20791:5270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004873
VERSION     KCVT01004873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20791:5270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82398.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          117 g          111 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggtc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004874             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:22567:9664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004874
VERSION     KCVT01004874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22567:9664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82399.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          124 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggaaatcaaa cgag
//
LOCUS       KCVT01004875             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:18600:17305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004875
VERSION     KCVT01004875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18600:17305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..442
                     /note="immunoglobulin light chain variable region"
     V_region        122..442
     V_segment       122..404
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82400.1"
                     /translation="YQQYSDFLLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          103 a          130 c          117 g           95 t
ORIGIN      
        1 acatgggtca acgcagagta catgggggag gaactgctca gttaggaccc agagggaacc
       61 atggaagccc cagcacagct tctcttcctc ctgctgctct ggatcccaga taccgccgga
      121 aaaattgtca tgacgcagtc tccagccacc ctgtctttgt ctccagggga aacagccacc
      181 ctctcctgca gggccagtga gagtgttggc accttcttag cctggtacca acagaaacct
      241 gggcaggctc ccaagctcct tgtccatagt gctttcttca gggcccctgg catcccagac
      301 aggttcagtg gcagcgggtc taggacagag ttcactctca ccatcaacac cctggagcct
      361 gaagatgttg gagtttatca ctatcagcag tatagtgact tcctgctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01004876             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12818:16146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004876
VERSION     KCVT01004876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12818:16146"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..439
                     /note="immunoglobulin light chain variable region"
     V_region        137..439
     V_segment       137..420
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <398..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82401.1"
                     /translation="CQKYSSSPFTF"
     J_segment       421..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           96 a          129 c          117 g           97 t
ORIGIN      
        1 acatggggag agcccatatc aatgcctggg tcagagctct ggagaagagc tgctcagtta
       61 ggacccagag agaaccatgg aaatcccagc tcagcttctc ttcctcctgc tactgtggct
      121 cccaggtacc accggacaag ttattttgac tcagtctcca gccaccctgt ctttgtctcc
      181 aggggaaaga gccaccctct cctgcagggc cagtcagagt gttggcagca gcttagcctg
      241 gtaccagcag aaacctgggc aggcccccag actcctcgtc tatggtgcat ccaggagggc
      301 cactggcatc ccagacaggt tcagtggcag tgggtctggg acagagttca ctctcaccat
      361 cagcagcctg gagcctgaag attttgcagt gtattactgt cagaagtata gtagttcccc
      421 attcactttc ggccccggg
//
LOCUS       KCVT01004877             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8387:9547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004877
VERSION     KCVT01004877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8387:9547"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82402.1"
                     /translation="CLQFKTYPNSF"
     J_segment       382..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          117 c          106 g          100 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatctc ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctcag ctcctcatct
      241 atgctgcatc cagtttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc accagcctgc agcctgaaga ttttgcaact tatttctgtc
      361 tgcagtttaa aacttacccg aacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004878             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17412:13323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004878
VERSION     KCVT01004878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17412:13323"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82403.1"
                     /translation="CQQYNSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          112 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aaggccttga
      241 tctattacgc gtccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004879             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10052:9732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004879
VERSION     KCVT01004879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10052:9732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82404.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagtctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004880             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:9895:11521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004880
VERSION     KCVT01004880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9895:11521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..351
                     /note="immunoglobulin light chain variable region"
     V_region        12..351
     V_segment       12..313
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <291..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82405.1"
                     /translation="CMQPLEFPWTF"
     J_segment       314..351
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>354
                     /gene="IGKC"
BASE COUNT           83 a           87 c          101 g           83 t
ORIGIN      
        1 acatgggtgg ggacattgtg atgacccaga ttccactctc cctgcccgtc acccttggag
       61 agccggcctc catctcctgc aggtctagtc agagcctctt ggatagtgag gatggaaaca
      121 cttatttgga atggtacctg cagaagccag gccagtctcc acagctcttg atttatgagg
      181 tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt
      241 tcacactgaa aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaac
      301 ctctagagtt tccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01004881             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11514:13328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004881
VERSION     KCVT01004881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11514:13328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82406.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       389..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g          102 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acactcagtt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg gacaagtcag
      181 gacattagca gttatttagc ctggtatcag cagaaaccag gtaaagcccc taacctcctg
      241 atctataagg cgtccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaggctg aagattttgc agtttattac
      361 tgtcaacagc gtattggtta cccgtacatg tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01004882             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13907:13670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004882
VERSION     KCVT01004882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13907:13670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82407.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004883             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24037:20313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004883
VERSION     KCVT01004883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24037:20313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82408.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           91 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004884             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:24934:17836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004884
VERSION     KCVT01004884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24934:17836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82409.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004885             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19665:4599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004885
VERSION     KCVT01004885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19665:4599"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82410.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc ttagagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttaattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004886             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14465:20136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004886
VERSION     KCVT01004886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14465:20136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82411.1"
                     /translation="CVQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cgttcaagct ctagagtttc cgtggacttt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004887             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19107:8426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004887
VERSION     KCVT01004887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19107:8426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82412.1"
                     /translation="CQQGYSFPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           95 a          123 c          106 g           99 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcag tagtttaagc tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctttagggc atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tccagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagtttc cccttcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004888             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20691:11503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004888
VERSION     KCVT01004888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20691:11503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82413.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtctcc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gtttttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactggaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004889             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13225:15632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004889
VERSION     KCVT01004889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13225:15632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82414.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          125 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcggtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004890             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:22195:8913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004890
VERSION     KCVT01004890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22195:8913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82415.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          107 a          118 c          107 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagctgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gtcaggatat
      181 taatacctgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaagcgag
//
LOCUS       KCVT01004891             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16527:11468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004891
VERSION     KCVT01004891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16527:11468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82416.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactgtcc ctgcccgtca cccttggaga gccggcctcc atctcctgtg ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01004892             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11348:6866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004892
VERSION     KCVT01004892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11348:6866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82417.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           93 a          120 c          127 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accctctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacgtagtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agtcggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttccaagcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 gggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01004893             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17891:13351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004893
VERSION     KCVT01004893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17891:13351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82418.1"
                     /translation="CQQGYSYPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          120 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tataggagac acagtcacca tcacttgcca ggcgagtcaa
      181 ggcattgaca ataatttaaa ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atctttgggg catccacttt ccaaagtggg actccctcgc ggttcagcgg cagtgaatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttatttc
      361 tgtcaacagg gttatagtta ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01004894             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11621:2582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004894
VERSION     KCVT01004894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11621:2582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82419.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggtctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004895             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:7790:7622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004895
VERSION     KCVT01004895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:7790:7622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82420.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004896             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9905:2785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004896
VERSION     KCVT01004896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9905:2785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82421.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          116 c          101 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggaaaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc ttccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004897             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8115:10235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004897
VERSION     KCVT01004897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8115:10235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82422.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcatccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004898             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12414:6576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004898
VERSION     KCVT01004898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12414:6576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82423.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          117 c          107 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccgtc
      121 ttccctgtct gcttctctag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagcagttct ttacattggt ttcaacacaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc agagtggaga tcaaacgag
//
LOCUS       KCVT01004899             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12209:2637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004899
VERSION     KCVT01004899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12209:2637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82424.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004900             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18565:19617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004900
VERSION     KCVT01004900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18565:19617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82425.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004901             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13310:11269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004901
VERSION     KCVT01004901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13310:11269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82426.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004902             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20143:10847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004902
VERSION     KCVT01004902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20143:10847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82427.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004903             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:27317:18769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004903
VERSION     KCVT01004903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:27317:18769"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82428.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcccgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004904             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20534:9224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004904
VERSION     KCVT01004904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20534:9224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82429.1"
                     /translation="CLQYKSYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          116 c          108 g           99 t
ORIGIN      
        1 acatggggca gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgccc gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcttctgta ggagacactg tcaccatcac ttgccgggca agtcagggtc
      181 ttagtagctc tttacattgg tttcagcaga aaccagggaa agcccctagg ctcctgatct
      241 atgctgcatc cactttggca ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagagttcac tctcaccatc agcagcctgc agcctgaaga tattggtact tattactgtc
      361 tacagtataa aagttacccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004905             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13534:17383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004905
VERSION     KCVT01004905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13534:17383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82430.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcggc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctctcgga tggtgaggat ggaaacacct acttagaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga tatcaaacga g
//
LOCUS       KCVT01004906             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16683:4032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004906
VERSION     KCVT01004906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16683:4032"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82431.1"
                     /translation="CLQGYSAPFTF"
     J_segment       383..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          102 a          118 c          106 g           97 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcttcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccagg aaaaactcct cagcgcctga
      241 tctatgctgc atccagtttg gagagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gcacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca gcttattact
      361 gtctacaggg ttatagtgcc ccattcactt tcggccccgg gaccaaactg gatatcaaaa
      421 gag
//
LOCUS       KCVT01004907             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25539:10339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004907
VERSION     KCVT01004907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25539:10339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82432.1"
                     /translation="CQQYNSLPYSF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          104 a          109 c          109 g           99 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttgagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcaccatca cttgccgggc aagtcagggc
      181 gttaacgttt atttaaattg gtatcagcag aaaccgggga aagcccctaa gcccctgatc
      241 ttttatgcaa accgtttgga acgtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaag ttattattgt
      361 caacagtata atagtttacc gtacagtttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01004908             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12976:9960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004908
VERSION     KCVT01004908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12976:9960"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82433.1"
                     /translation="CLQFKTYPNSF"
     J_segment       387..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           97 a          118 c          108 g          102 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atctcttgcc gggcaagtca
      181 gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc ctcagctcct
      241 catctatgct gcatccagtt tggccggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttctctctca ccatcaccag cctgcagcct gaagattttg caacttattt
      361 ctgtctgcag tttaaaactt acccgaacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01004909             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16377:6172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004909
VERSION     KCVT01004909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16377:6172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82434.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          124 c          112 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcatcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004910             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11703:9961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004910
VERSION     KCVT01004910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11703:9961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82435.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          122 c          119 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattctgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgaaga tggaaacacc tatttgcact ggtacctgaa gaagccaggc
      241 cagtctccac agctcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004911             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15030:5012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004911
VERSION     KCVT01004911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15030:5012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..441
                     /note="immunoglobulin light chain variable region"
     V_region        104..441
     V_segment       104..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82436.1"
                     /translation="CMQSLDFPLTF"
     J_segment       406..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>446
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          108 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg ttatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ctggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacacaga tttcacactg aaaatcacca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca gtctctagat tttccgctca ctttcggtgg
      421 agggaccaag gtggagatca atcgag
//
LOCUS       KCVT01004912             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11359:10065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004912
VERSION     KCVT01004912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11359:10065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82437.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttacgaatga tttagcctgg tatcaacaga aaccagataa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01004913             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12612:5407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004913
VERSION     KCVT01004913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12612:5407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..428
                     /note="immunoglobulin light chain variable region"
     V_region        107..428
     V_segment       107..390
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82438.1"
                     /translation="CLQYKSFPYSF"
     J_segment       391..428
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          108 a          116 c          103 g          104 t
ORIGIN      
        1 acatggggct tgcaggagtc agacacagtc aggacacagc ttggacatga gggcccccgc
       61 tcatctccta gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac
      121 tcagtctcca tcttccctgt ctgcatctgt gggagacact gtcaccatca cttgccggac
      181 aagtcaaggt attaccagtt atttacattg gtttcagcag aaaccaggga aagcccctaa
      241 gctcctgatc tatgaaacat ccactttggt aagtggggtc ccatcaaggt tcagcggcag
      301 tgcatctggg acagaattca ctctcaccat cagcagccta cagcctgaag attttgcatc
      361 ttattactgt ctacagtata aaagtttccc gtacagtttt ggccagggga ccaaagtgga
      421 gatcaaacga g
//
LOCUS       KCVT01004914             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12184:12432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004914
VERSION     KCVT01004914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12184:12432"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82439.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccatacggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004915             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20179:9372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004915
VERSION     KCVT01004915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20179:9372"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82440.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtcaagtca
      181 gagcctcctg gatagtgagg atggaaacac ctatttgcac tggtacttga agaagccagg
      241 ccagtctcca caggtcttaa tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004916             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22784:5742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004916
VERSION     KCVT01004916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22784:5742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82441.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctt tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004917             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10458:10458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004917
VERSION     KCVT01004917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10458:10458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82442.1"
                     /translation="CLQYKSYPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          114 c           99 g          103 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gttattatca attatttaaa ttggtttcag cagaaaccag ggaaagcccc taagctcctg
      241 atttatgctg catccagatt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaagtta cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01004918             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14615:10959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004918
VERSION     KCVT01004918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14615:10959"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82443.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004919             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21297:13485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004919
VERSION     KCVT01004919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21297:13485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..402
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82444.1"
                     /translation="CMQNTEDPTF"
     J_segment       403..433
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>439
                     /gene="IGKC"
BASE COUNT          101 a          120 c          113 g          105 t
ORIGIN      
        1 acagggggga ctgatcagga ctcctcagtt catcttctca cgatgagact ccctgctcag
       61 ctcctcgggc tgttgatgct ctgggtccct gggtccagtg gggatattgt gatgacccag
      121 actccactct cgctgcccgt cacccctgga gagccggcct ccatctcctg caggtctagt
      181 caaagccttc tgcatagtaa tggaaacacc tatttgcatt ggtacctgca gaagccaggc
      241 cagtctccac gtctcctgat ctataaagtt accaatcggg aatctggggt cccagacagg
      301 ttcagtggca gtgggtcagg cacagatttc acactgaaaa tcagcagggt ggagcctgaa
      361 gatgttggtg tttattattg catgcaaaat acagaagatc ccactttcgg ccccgggacc
      421 aaactggata tcatacgag
//
LOCUS       KCVT01004920             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11366:12379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004920
VERSION     KCVT01004920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11366:12379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..311
                     /note="immunoglobulin light chain variable region"
     V_region        8..311
     V_segment       8..273
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <251..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82445.1"
                     /translation="CMQALEFPWTF"
     J_segment       274..311
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>314
                     /gene="IGKC"
BASE COUNT           78 a           72 c           91 g           73 t
ORIGIN      
        1 acatggggtc acccttggag agccggcctc catctcctgc aggtctagtc agagtctctt
       61 ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag gccagtctcc
      121 acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca ggttcagtgg
      181 cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      241 ggtttattac tgcatgcaag ctctagaatt tccgtggacg ttcggccaag ggaccaaggt
      301 ggaaatcaaa cgag
//
LOCUS       KCVT01004921             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22342:9487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004921
VERSION     KCVT01004921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22342:9487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82446.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          125 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gatgctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01004922             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21086:17896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004922
VERSION     KCVT01004922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21086:17896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82447.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          116 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcac cagcagctta gcctggtatc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga taggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004923             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23121:10811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004923
VERSION     KCVT01004923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23121:10811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82448.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004924             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:26202:5495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004924
VERSION     KCVT01004924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:26202:5495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82449.1"
                     /translation="CQHYNSSPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          116 c          104 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgaccgagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaagcc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga atacactctc accatcagca gtctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca ctataacagt agcccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01004925             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:25239:16587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004925
VERSION     KCVT01004925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25239:16587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82450.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacctgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01004926             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19136:3449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004926
VERSION     KCVT01004926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19136:3449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..247
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <225..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82451.1"
                     /translation="CQQVYTNPAF"
     J_segment       250..282
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>285
                     /gene="IGKC"
BASE COUNT           79 a           71 c           70 g           65 t
ORIGIN      
        1 acatgggagg agacagagtc accatctctt gccgggcaag tcagaacatt tataggaatt
       61 tagcgtggta tcagcagaaa ccagggaaag cccctaaact cctgatctat gctgcatcca
      121 gattgcacag tgggtttccc tctcggttca gcggcagtgg atctgggaca gatttcactc
      181 tcaccatcag caacctacag cctgaagatt ctgcagttta ttactgtcaa caggtttata
      241 ctaacccggc gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01004927             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22018:13740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004927
VERSION     KCVT01004927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22018:13740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..372
                     /note="immunoglobulin light chain variable region"
     V_region        36..372
     V_segment       36..334
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82452.1"
                     /translation="CMQSIKDPFTF"
     J_segment       335..372
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>375
                     /gene="IGKC"
BASE COUNT           91 a          100 c           96 g           88 t
ORIGIN      
        1 acatggggat gctctgggtc cctggatcca gtggggatat tgtgatgacc cagaccccac
       61 tctcggtgcc cgtcacccct ggagagccgg cctccatctc ctgcaggtct agtcaaagcc
      121 ttctccatag taatggagac acctatttac attggtacct tcagaggtca ggccagtctc
      181 cacggctcct gatctataaa gtaaccaatc ggctacctgg ggtcccagac aggttcagtg
      241 gcagtgggtc aggcacagat ttcacactga aaatcagcag ggtggagcct gaggatattg
      301 gtgtttattt ctgcatgcaa agtataaaag atccattcac tttcggcccc gggaccaaac
      361 tggatatcaa acgag
//
LOCUS       KCVT01004928             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10028:14751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004928
VERSION     KCVT01004928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10028:14751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..399
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82453.1"
                     /translation="CMQGIQLPPTF"
     J_segment       402..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           86 a          126 c          125 g          102 t
ORIGIN      
        1 acatgggggg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctg
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtcaagtcag
      181 agcctccaac ttggtaatgg atacacttat ctgttttggt acctgcagaa gccgggccag
      241 tctccacagc tcctgatcta tttgctttcc ggccgggcct ctggagtccc tgacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgcat gcaaggtata cagcttcctc cgacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004929             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17144:20124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004929
VERSION     KCVT01004929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17144:20124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82454.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcaacagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc gctttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004930             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4620:7727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004930
VERSION     KCVT01004930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4620:7727"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82455.1"
                     /translation="CQQGNSRPPTF"
     J_segment       386..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          113 c          108 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gaagtgacat tcagatgtcc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaccaatta tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 tttatgcaga cagtttggca agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagggaaa tagtcgtcct cccacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004931             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16112:9305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004931
VERSION     KCVT01004931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16112:9305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82456.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc ctgcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01004932             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7062:10675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004932
VERSION     KCVT01004932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7062:10675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..285
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82457.1"
                     /translation="CQQHDDSPRTF"
     J_segment       287..322
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           93 a           85 c           79 g           68 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc
       61 atcacttgca gagccagtca ggatattaac acctggttgg cctggtatca acagaagcca
      121 gggaaagccc ctaaggtcct gatctatagg acatccaatt tggaaacagg ggtcccatca
      181 aggttcagtg gaagtggatc tgggacagat ttcactctca ccatcaacag cctgcagcct
      241 gaagatatcg caacatatta ctgtcaacag catgatgatt cccctcggac gttcggccaa
      301 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01004933             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:20128:13884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004933
VERSION     KCVT01004933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20128:13884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82458.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          109 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccat gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcatcaacta ttatttaaat tggtatcagc agatgccggg gaaagcccct aaggtcctga
      241 tctattatac aaatcgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004934             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:4584:12599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004934
VERSION     KCVT01004934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4584:12599"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82459.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatctca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004935             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:10252:4501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004935
VERSION     KCVT01004935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10252:4501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82460.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggt ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004936             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24689:5210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004936
VERSION     KCVT01004936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24689:5210"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82461.1"
                     /translation="CLQYNSSPLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacatagca tggacatgag ggtccctgct cagttcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgccgggcg agtcagacta
      181 ttagcagctg gttagactgg tatcagcaga aaccagggaa agcccctaac ctcctgatct
      241 ttaaggcatc cagtttgcaa agtggggtcc cctcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 tacagtacaa tagtagcccg ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01004937             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21596:2515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004937
VERSION     KCVT01004937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21596:2515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82462.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01004938             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10677:8330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004938
VERSION     KCVT01004938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10677:8330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..312
                     /note="immunoglobulin light chain variable region"
     V_region        152..312
     V_segment       152..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82463.1"
                     /translation="CLQPLEFPWTF"
     J_segment       275..312
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           68 a           87 c           89 g           71 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcttgcaa cctctagagt ttccgtggac gttcggccaa gggaccaagg
      301 tggaaatcaa acgag
//
LOCUS       KCVT01004939             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7762:14063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004939
VERSION     KCVT01004939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7762:14063"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82464.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          124 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cacttataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccagactgga tgtcaaacga g
//
LOCUS       KCVT01004940             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16382:6246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004940
VERSION     KCVT01004940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16382:6246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82465.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          117 c          107 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcagacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt ccctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01004941             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13307:17029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004941
VERSION     KCVT01004941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13307:17029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..376
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82466.1"
                     /translation="CQQSYRYPLTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          101 a          116 c          108 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgagaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 gtatcttgcg tccactttac agagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcgcca tcagcagcct gcagcctgaa gatgctgcaa cttattactg
      361 tcagcagagt tatcgttatc cgctcacttt cggtggaggg acccaggtgg aaatcaatcg
      421 ag
//
LOCUS       KCVT01004942             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14020:15001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004942
VERSION     KCVT01004942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14020:15001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82467.1"
                     /translation="CLQYNTYPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          116 c           95 g          105 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 gtattagcaa ttctttagat tggtttcagc agaaaccagg gaaagtccct aaactcctga
      241 tctatactac atccattttg gtaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca acttattact
      361 gtctacagta taacacttac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004943             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13711:13710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004943
VERSION     KCVT01004943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13711:13710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    167..321
                     /note="immunoglobulin light chain variable region"
     V_region        167..321
     V_segment       167..280
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <263..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82468.1"
                     /translation="CQQSYRYPLTF"
     J_segment       286..321
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>326
                     /gene="IGKC"
BASE COUNT           71 a           93 c           89 g           73 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcaggagtg gggtcccatc
      181 aaggttcagc ggcagtggat ctgggacaga tttcactctc gccatcagca gcctgcagcc
      241 tgaagatgct gcaacttatt actgtcagca gagttatcgt tatccgctca ctttcggtgg
      301 agggacccag gtggaaatca atcgag
//
LOCUS       KCVT01004944             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21161:10792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004944
VERSION     KCVT01004944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21161:10792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82469.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          123 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004945             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:2200:15638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004945
VERSION     KCVT01004945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:2200:15638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82470.1"
                     /translation="CQQYTSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          121 c          106 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 acgttagcag tcatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttatcact
      361 gtcaacagta cactagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01004946             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15620:7317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004946
VERSION     KCVT01004946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15620:7317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82471.1"
                     /translation="CQQYNSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          114 c          108 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcgagtc
      181 agggcattag aagttattta gcgtggtatc agcagaaacc aggaaaagcc ccgaaggcct
      241 tgatctatta cgcatccatt ttagaaagtg cggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagtc tgacgatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01004947             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6881:11479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004947
VERSION     KCVT01004947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6881:11479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82472.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          118 c          111 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004948             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5602:13808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004948
VERSION     KCVT01004948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5602:13808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82473.1"
                     /translation="CMQGLEFPPTF"
     J_segment       403..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          124 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggcgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggtgatg gaaacaccta tttggaatgg ttcctccaga ggccaggcca
      241 gtctccacac ctcttgattt atggggcttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggtct agagtttcct ccgacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01004949             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:25176:20541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004949
VERSION     KCVT01004949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25176:20541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82474.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004950             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23450:20628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004950
VERSION     KCVT01004950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23450:20628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..375
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82475.1"
                     /translation="CQQYNSIPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          111 c          108 g           97 t
ORIGIN      
        1 acatggggca gtcagtccca gtcaggacac agcatggaca tgagggtccc cactcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagct gacgcagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcgagtcag
      181 ggcattaaca tttatttaag ttggtatcag cagaaaccag ggaaagcccc taagcccctg
      241 atctattatg catccagttt ggaaacaggg gtaccatcaa ggttcagtgg gagtggatct
      301 gggacagatt atactctcac catcagcagt ctgcagcctg aagatattgc aacatattac
      361 tgtcaacagt ataattctat cccgtacagt tttggccagg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004951             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11677:16144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004951
VERSION     KCVT01004951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11677:16144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82476.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtgggggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004952             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19321:19237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004952
VERSION     KCVT01004952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19321:19237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82477.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          101 a          116 c          115 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcaacag aaaccaggac aacctcctaa
      241 actcctgatt taccaagcaa tcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctagg accgatttca ccctcacaat taatcctgtg gaacctgacg atggtgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01004953             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12686:15201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004953
VERSION     KCVT01004953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12686:15201"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82478.1"
                     /translation="CIQSLEFPWTF"
     J_segment       406..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          110 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccactg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccttctcctg taggtctagt
      181 cacagcctct tggatagtga ggatggaaat atccatttgg attggtatct gcagaagcca
      241 ggccagtctc cacacctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggtttagtg gcagtgggtc agacactgat ttcacactga aaatcagcag ggtggaggct
      361 gaggatgttg gggtttacta ctgcatacag tctctagagt ttccttggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01004954             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12360:10701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004954
VERSION     KCVT01004954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12360:10701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82479.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          119 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattcctgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004955             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10418:14044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004955
VERSION     KCVT01004955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10418:14044"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82480.1"
                     /translation="CVQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aggccaggcc
      241 agtccccaca actcttgact tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc gttcaagctc tagagtttcc gtggactttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01004956             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20144:8324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004956
VERSION     KCVT01004956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20144:8324"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82481.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          116 c          108 g           87 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcaggata
      181 ttaacaactg gttggcctgg tatcaacaga aaccagggaa agcccctaag gtcctgatct
      241 atagggcatc cattttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01004957             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23837:6300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004957
VERSION     KCVT01004957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23837:6300"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82482.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          118 c          109 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagcc
      181 acgatataaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaagctcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc agcatcagca gcctgcagcc tgaagatttc gcaacatatt
      361 tctgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01004958             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20476:6542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004958
VERSION     KCVT01004958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20476:6542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82483.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctttgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01004959             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12988:10483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004959
VERSION     KCVT01004959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12988:10483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82484.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccgctgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggagcctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01004960             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:23036:18172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004960
VERSION     KCVT01004960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23036:18172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82485.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          122 c          117 g          106 t
ORIGIN      
        1 acatggggac gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggagcctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004961             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24292:10710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004961
VERSION     KCVT01004961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24292:10710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82486.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004962             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:7558:18974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004962
VERSION     KCVT01004962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7558:18974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    136..457
                     /note="immunoglobulin light chain variable region"
     V_region        136..457
     V_segment       136..419
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <397..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82487.1"
                     /translation="CQQYDSDPFTF"
     J_segment       422..457
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>460
                     /gene="IGKC"
BASE COUNT          114 a          124 c          119 g          103 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtttccaatc
      121 tcaggtgcca aatgtgacat ccagatgacc cagtctccat cctccctgtc tgcatctgta
      181 ggagacagag tcaccatcac ttgtcgggcg agtcagggca ttcgcagtta tttagcgtgg
      241 tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc cactttggaa
      301 agtggggtcc catcaaggtt cagcggcagt ggatatggga cagaattcac tctcatcatc
      361 agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtatga cagtgacccg
      421 ttcactttcg gtggagggac caaggtagaa atcaaacgag
//
LOCUS       KCVT01004963             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21798:14600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004963
VERSION     KCVT01004963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21798:14600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82488.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aaaccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01004964             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12315:3887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004964
VERSION     KCVT01004964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12315:3887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82489.1"
                     /translation="CQQYHSLPLTF"
     J_segment       380..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          103 g           98 t
ORIGIN      
        1 acatgggcag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacagttat ttaaattggt atcagcagaa accggggaaa gcccctcaac tcctgatcta
      241 ttattcaaac cgtttggaaa cgggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccatca tcagcctgca acctgaagat tttgtaactt attactgtca
      361 acagtatcat agtttacctc tcactttcgg cggagggacc aaggtggaga tcagacgag
//
LOCUS       KCVT01004965             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9931:18427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004965
VERSION     KCVT01004965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9931:18427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82490.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgcg tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01004966             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12308:11472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004966
VERSION     KCVT01004966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12308:11472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82491.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          113 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004967             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17817:11675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004967
VERSION     KCVT01004967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17817:11675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82492.1"
                     /translation="CQMYINSPFTF"
     J_segment       390..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          101 a          126 c          109 g           94 t
ORIGIN      
        1 acatggggga gagaagagct gctcagttag gacccagaga gaaccatgga aatcccagct
       61 cagcttctct tcctcctgct actgtggctc ccaggcacca ccggacaagt tatattgact
      121 cagtctccag ccaccctgtc tttgtctcca ggggaaagag ccaccctctc ctgcagggcc
      181 agtcagagtg ttggtagcag cttagcctgg taccagcaga aacctgggca ggcccccagg
      241 ctcctcatct atggtgcatc cagcagggcc actggcatcc cagacaggtt cagtggcagt
      301 gggtctggga cagagttcac tctcagtatc cgcagcctgg aacctgaaga ttttgcagta
      361 tattactgtc agatgtatat taactcccca ttcactttcg gccccgggac caaactggat
      421 atcaaacgag
//
LOCUS       KCVT01004968             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:29307:11614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004968
VERSION     KCVT01004968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:29307:11614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82493.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           92 t
ORIGIN      
        1 acatgggggg tcatacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01004969             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:22794:8741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004969
VERSION     KCVT01004969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22794:8741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82494.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          109 c          111 g           98 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctctggggga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agatatttaa attggtatca gcagaaaccg gggaaagccc ctaagttcct
      241 gatctattat gtaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ttgtcaacag tataatagtt taccgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004970             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5982:11151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004970
VERSION     KCVT01004970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5982:11151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82495.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          114 c          111 g           94 t
ORIGIN      
        1 acatggggag aaccactcag gtcacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggcag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004971             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11827:4593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004971
VERSION     KCVT01004971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11827:4593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82496.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004972             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14734:20297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004972
VERSION     KCVT01004972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14734:20297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82497.1"
                     /translation="CMQALEFPWTF"
     J_segment       282..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           73 a           81 c           91 g           77 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      181 ttcagtggga gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      241 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01004973             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14399:9005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004973
VERSION     KCVT01004973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14399:9005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82498.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tattgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcatgg atagtgggga tgtaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac atctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacggatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtacagttt tggccagggg
      421 accagagtgg agatcaaacg ag
//
LOCUS       KCVT01004974             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23514:6310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004974
VERSION     KCVT01004974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23514:6310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82499.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004975             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19137:7637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004975
VERSION     KCVT01004975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19137:7637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..384
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82500.1"
                     /translation="CQQRNSYPYMFSF"
     J_segment       394..428
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          102 a          112 c          112 g          105 t
ORIGIN      
        1 acatgggggg agttagaccc agtctggacg cagcatggac atcagggtcc tcgctcagct
       61 tctcgggctc ctgctgctct ggctcccagg tgccagatgt gacattcagt tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcact atcacttgtc gggcaagtca
      181 ggacattggt agttttttag cctggtatca acagaaacca gggaaagccc ctgacctcct
      241 gatctataag gcgtccagtt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagtttatta
      361 ctgtcaacaa cgtaatagtt acccgtacat gttcagtttt ggccagggga ccaaagtgga
      421 gatcaaacga g
//
LOCUS       KCVT01004976             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19547:2559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004976
VERSION     KCVT01004976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19547:2559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82501.1"
                     /translation="CFQDKQLPVTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           90 a          121 c          120 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtaatg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttgggattta ttactgcttc caagataaac agcttcctgt cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01004977             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22035:11526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004977
VERSION     KCVT01004977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22035:11526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82502.1"
                     /translation="CQQHNTYPYTF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          110 a          118 c          107 g           92 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggagccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacacagtca ccatcacttg tcgggcaagt
      181 caggacatta gtaatgattt agcctggtat cagcagaaac cagggaaagc cccaaagccc
      241 ctgatctttt acgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcaac agcataatac ttacccgtac acttttggcc aggggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01004978             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22522:11257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004978
VERSION     KCVT01004978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22522:11257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82503.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          118 c          106 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgaa actttttatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01004979             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16347:5166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004979
VERSION     KCVT01004979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16347:5166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82504.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          123 c          116 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtatca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcggtg gcagtgggtc
      301 tgagacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004980             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:8251:16869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004980
VERSION     KCVT01004980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8251:16869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82505.1"
                     /translation="CLQYKSFPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          113 c           99 g          101 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccttcac ttgccggaca agtcaaggta
      181 ttaccaatta tttacattgg tttcagcaca aaccagggaa agcccctaag ctcctgatct
      241 atgaaacatc cagtttggta agtggggtcc catcaaggtt cagcggcagt gcatctggga
      301 cagaattcac tctcaccatc agcagcctac agcctgaaga ttttgcatct tattactgtc
      361 tacagtataa aagtttcccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01004981             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23092:8705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004981
VERSION     KCVT01004981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23092:8705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82506.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          117 c          113 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacccgtt cactttcggt ggagggacca aggtagagat
      421 caaacgag
//
LOCUS       KCVT01004982             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21174:13790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004982
VERSION     KCVT01004982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21174:13790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82507.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004983             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20973:12385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004983
VERSION     KCVT01004983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20973:12385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82508.1"
                     /translation="CMQAREFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          117 c          124 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca ctcttggaga gccggcctcc atctcctgca tgtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatgtggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tcgagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01004984             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10716:19254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004984
VERSION     KCVT01004984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10716:19254"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..393
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82509.1"
                     /translation="CLQSKNSPWSF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          101 a          116 c          118 g           99 t
ORIGIN      
        1 acatggggag gagcagcctc tagttcagct ctcagaaatg gggtcctggg ctcctttcct
       61 gtggatcctc ctgctctgtg ctccaggctg cagtggggac attgtgctga cccagtctcc
      121 agcctctttg gccgtgtctc cagggcagag ggccaccatc acctgcagag ccagtgagag
      181 tgtcagtgcc tttggaataa gcctcattca ctggtatcaa cagaaaccag gacaacctcc
      241 taaactcctg atttaccaag caatcaataa ggagactggg gtcccagcca ggttcagcgg
      301 cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaacctg acgatggtgc
      361 agattattac tgtctgcaga gtaagaattc tccgtggtcg ttcggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01004985             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14643:2005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004985
VERSION     KCVT01004985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14643:2005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..298
                     /note="immunoglobulin light chain variable region"
     V_region        8..298
     V_segment       8..260
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <238..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82510.1"
                     /translation="CQQYDSLPYSF"
     J_segment       262..298
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        299..>301
                     /gene="IGKC"
BASE COUNT           85 a           66 c           75 g           75 t
ORIGIN      
        1 acatgggtgt ctgcgtctgt aggagacaca gtcaccattc cttgccgggc aagtcagggc
       61 attagcaatt atttaaattg gtatcagcag aaaccgggga aagcccctaa ggtcctgatc
      121 tattatacaa atcgtttgga aagtggggtc ccatcaaggt tcagcggcag cggatctgga
      181 acagaattca ctctcaccat cagtggccta cagcctgagg attttgcaac ttattactgt
      241 caacagtatg atagtttacc atacagtttt ggccagggga ccaaagttga gatcaaacga
      301 g
//
LOCUS       KCVT01004986             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:3619:17237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004986
VERSION     KCVT01004986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3619:17237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82511.1"
                     /translation="CQQYDKSPPTF"
     J_segment       381..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          117 c          113 g           85 t
ORIGIN      
        1 acatgggagt ctcagacagg acacagcatg gacacgaggg tccccgctca gctcctgggg
       61 ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagggtc accatcactt gcagagccag tcagggtatc
      181 agcaactggt tggcctggta tcaacagaaa ccagggagag cccctaacct cctgatgtat
      241 agggcgtcca atttgcaagg aggggtccca tcaaggttca gaggaagtgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaggatg tcgctacata ttactgtcaa
      361 cagtatgata agtcccctcc gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01004987             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14106:11471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004987
VERSION     KCVT01004987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14106:11471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82512.1"
                     /translation="CQQYNSLPLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          107 c          107 g           99 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga ggttctccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 attagcagat atttaaattg gtatcagcag aaaccgggga aagcccctaa gttcctgatc
      241 tattatgtaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcaac ttattattgt
      361 caacagtata acagtttacc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01004988             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17336:15204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004988
VERSION     KCVT01004988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17336:15204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82513.1"
                     /translation="CQQYNNLPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          113 a          113 c          108 g           93 t
ORIGIN      
        1 acatggggca ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacactca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg ccgggcaagt
      181 caggacatta aaatttattt gaactggtat cagcagaaac cggggaaagc ccctaacctc
      241 ctgatctatt atggaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tcagggacag aattcactct caccatcagc agcctgcaac ctgaggattt tgcatcttat
      361 tactgtcaac agtataataa tttaccgtgg acattcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01004989             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9939:11331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004989
VERSION     KCVT01004989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9939:11331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    49..370
                     /note="immunoglobulin light chain variable region"
     V_region        49..370
     V_segment       49..318
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <310..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82514.1"
                     /translation="CLQGDTAPFTF"
     J_segment       335..370
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>373
                     /gene="IGKC"
BASE COUNT           88 a           98 c           98 g           89 t
ORIGIN      
        1 acatgggtcc tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg
       61 acccagtctc catcttccct gtctgcatcg gcaggagaca gagtcaccat cacttgccgg
      121 gcaagtcagg gcattaacga ttatttaagt tggtatcagc agaaaccagg aaaacctcct
      181 aagcgcctga tttatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggt
      241 agtggatctg ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca
      301 gcttattact gtctacaggg tgatactgcc ccgttcactt tcggcggagg gaccaaggtg
      361 gagatcaaac gag
//
LOCUS       KCVT01004990             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10126:4987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004990
VERSION     KCVT01004990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10126:4987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82515.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt acaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01004991             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7841:19498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004991
VERSION     KCVT01004991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7841:19498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82516.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          118 c          112 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcactggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttattt
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01004992             379 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11923:19775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004992
VERSION     KCVT01004992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 379)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11923:19775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    55..376
                     /note="immunoglobulin light chain variable region"
     V_region        55..376
     V_segment       55..333
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>348
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82517.1"
                     /translation="CQQHDSYPLTF"
     J_segment       340..376
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        377..>379
                     /gene="IGKC"
BASE COUNT           95 a          108 c           94 g           82 t
ORIGIN      
        1 acatggggag gagtcagaac cactcagctc agctggctcc caggtgccag atgcgacatc
       61 cagatgaccc agtctccatc ctccctgtct gcatctgtag gagacacagt caccatcact
      121 tgtcgggcaa gtcaggacat tggtgaatct ttagcctggt atcagcagaa accagggaaa
      181 gccccgaagc ccctgatctt ttacgcatcc aatttggcaa gtggggtccc atcaaggttc
      241 agcggcagtg gatctgggac agccttcact ctcaccgtca gcagcctgca gcctgaagat
      301 tttgcaattt atacctgtca acaacatgat agttatcccc tcactttcgg cggagggacc
      361 aaggtggaca tcaaacgag
//
LOCUS       KCVT01004993             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10720:13143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004993
VERSION     KCVT01004993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10720:13143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82518.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcgtc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01004994             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10011:11109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004994
VERSION     KCVT01004994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10011:11109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82519.1"
                     /translation="CQQYDSDTRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          112 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacacgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01004995             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7254:13068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004995
VERSION     KCVT01004995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7254:13068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82520.1"
                     /translation="CMQALEFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           99 a          117 c          120 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tagagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctacagag gccaggccag
      241 tctccacagc tcttaattta tgaggtttcc taccgggcct ctggagtccc agagaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gaatttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01004996             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22119:21750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004996
VERSION     KCVT01004996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22119:21750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82521.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag gtaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01004997             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:11491:10925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004997
VERSION     KCVT01004997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11491:10925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82522.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc gctttggaaa gtggggtccc atcaagggtc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01004998             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15339:16307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004998
VERSION     KCVT01004998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15339:16307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82523.1"
                     /translation="CMQALEFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          125 c          115 g          106 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaggctcttg gatagtgagg atgaaagcac ctacttggaa tggtaccttc agaagccagg
      241 ccagtctcca cagttcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctggagttt ccattcactt tcggccccgg
      421 gaccaaactg gaaatcaaac gag
//
LOCUS       KCVT01004999             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13422:11484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01004999
VERSION     KCVT01004999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13422:11484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82524.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          117 c          123 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacttgca gaaggcaggc
      241 cagtctccac agctcatgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc aaactgaaca tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005000             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:28301:10441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005000
VERSION     KCVT01005000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:28301:10441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82525.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag tagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005001             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18533:3207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005001
VERSION     KCVT01005001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18533:3207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82526.1"
                     /translation="CQQYHNSPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          114 c          113 g           90 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acagccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggcattagca acaggttggc ctggtatcaa cagaaatcag ggaaagcccc taagctcttg
      241 atctctgggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggattt
      301 gggacagatt tcactctcat catcagcagc ctgcaggctg aagacatcgc aacatattac
      361 tgtcaacagt atcataattc cccgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005002             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12485:8266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005002
VERSION     KCVT01005002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12485:8266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82527.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005003             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12348:11466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005003
VERSION     KCVT01005003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12348:11466"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82528.1"
                     /translation="CQQYDSFPLTF"
     J_segment       387..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          117 c          110 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtgggaga cagagtcacc atcacttgcc gggctagtca
      181 ggacattagt aattttttaa attggtatca gcagaaaccg gggaaagccc ctaagctcct
      241 gatctattat ggaaaccgtt tgggaagcgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaggattttg cgacttatca
      361 ttgtcagcag tatgatagtt tccccctcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01005004             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19878:7033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005004
VERSION     KCVT01005004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19878:7033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82529.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          119 c          126 g          104 t
ORIGIN      
        1 acatgggggc tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005005             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14743:17377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005005
VERSION     KCVT01005005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14743:17377"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82530.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaagga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005006             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21191:11333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005006
VERSION     KCVT01005006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21191:11333"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..243
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <220..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82531.1"
                     /translation="CMQGLEFPRTF"
     J_segment       245..280
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>283
                     /gene="IGKC"
BASE COUNT           71 a           62 c           85 g           65 t
ORIGIN      
        1 acatggggca gatctagtca gagtctcttg gatagtgcgg atggaaacac ctatttggaa
       61 tggtacctgc agaagccagg ccagtctcca cagctcttga tttatgaggt ctccgaccgg
      121 gcctctggag tcccagacag gttcagtggc agtggctcag acactgattt cacactaaag
      181 atcagcagag tggaggctga ggatgttggg gtttattact gcatgcaagg tctagagttt
      241 cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005007             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16850:17017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005007
VERSION     KCVT01005007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16850:17017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..364
                     /note="immunoglobulin light chain variable region"
     V_region        87..364
     V_segment       87..322
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82532.1"
                     /translation="CQQYDSDSLTF"
     J_segment       327..364
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           92 a           97 c           99 g           79 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccagga gacagagtca ccatcacttg tcgggcgact
      121 caggacattc gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaggccc
      181 ttgatctatt acgcgtccac tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      301 tactgtcaac aatatgacag tgattcgctc actttcggtg gagggaccaa ggtggagatc
      361 aaacgag
//
LOCUS       KCVT01005008             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13213:19011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005008
VERSION     KCVT01005008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13213:19011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82533.1"
                     /translation="CYQHSRGWAF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           96 a          125 c          113 g           84 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccctctgc tactctggct cccaggtacc accggacaac ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccactctct cctgtagggc cagtgagaat
      181 gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccaccagggc cactgacatc ccagacaggt tcagtggcag tgggtctcgg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttggagt ctattactgc
      361 tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01005009             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:6293:20682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005009
VERSION     KCVT01005009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6293:20682"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82534.1"
                     /translation="CQQGYTTPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          112 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattagca gctggttagc ctggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atctataagg cgtccagttt ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcaacagc ctgcagcctg aagattttac aacttattat
      361 tgtcaacagg gttacactac ccctctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005010             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10862:19383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005010
VERSION     KCVT01005010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10862:19383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82535.1"
                     /translation="CQQGYSYPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          118 c          107 g           96 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgca ggagacacag tcaccatcac ttgccaggcg agtcaaggca
      181 ttggcaatac tttaaattgg tatcaacaga aaccggggaa agtccctaca ctcctgatct
      241 atagggcatc cggtttgcaa agtgggactc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttatccg tacagttttg gccaggggac caaactggag atcaaacgag
//
LOCUS       KCVT01005011             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20401:13005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005011
VERSION     KCVT01005011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20401:13005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82536.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggag aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccag cacaaacctg ggcaggctcc caagctcctc
      241 ctctatggtg catccaccag ggcctccggc atcccaggca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005012             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10879:4098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005012
VERSION     KCVT01005012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10879:4098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82537.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggtg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005013             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10717:10557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005013
VERSION     KCVT01005013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10717:10557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82538.1"
                     /translation="CQQGNSRPPTF"
     J_segment       386..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          112 c          109 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gaagtgacat tcagatgtcc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaccaatta tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 tttatgcaga cagtttggca agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcag tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagggaaa tagtcgtcct cccacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01005014             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:21789:7745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005014
VERSION     KCVT01005014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21789:7745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82539.1"
                     /translation="CQQGYSYPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          117 c          108 g           92 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaataat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgatctc
      241 taaggcatcc agtttgcaaa gtgggattcc ctctcggctc agcggcagtg gatctggggc
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt actactgtca
      361 acagggttat agttacccgt ggacattcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005015             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5862:10636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005015
VERSION     KCVT01005015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5862:10636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82540.1"
                     /translation="CLQGYNTPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          109 g           94 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagttgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcacc tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc gcctgatcta
      241 tgctgtgtcc agtttggaag gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat cttgcgactt attactgtct
      361 acagggttat aataccccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005016             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19308:18519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005016
VERSION     KCVT01005016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19308:18519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82541.1"
                     /translation="CQQGYTYLYNF"
     J_segment       382..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          116 c          105 g          101 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccggatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gttggagaca cagtcaccat cacttgccag gcgagtcacg
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctga
      241 tttatagggc atccagtttg caaagtgggt ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ctgtacaatt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005017             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12257:15507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005017
VERSION     KCVT01005017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12257:15507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82542.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          120 c          122 g           86 t
ORIGIN      
        1 acatgggggg ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01005018             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:10141:15307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005018
VERSION     KCVT01005018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10141:15307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..319
                     /note="immunoglobulin light chain variable region"
     V_region        8..319
     V_segment       8..277
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82543.1"
                     /translation="CQQYDSDSLTF"
     J_segment       282..319
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           80 a           83 c           83 g           76 t
ORIGIN      
        1 acatgggtga cccagtctcc atcctccctg tctgcatctg ttggagacag agtcaccatc
       61 acttgtcggg cgactcagga cattcgcagt tatttagcgt ggtatcagca gaaaccaggg
      121 aaagccccga agcccttgat ctattacgcg tccactttgg aaagtggggt cccatcaagg
      181 ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa
      241 gattttgcaa cttattactg tcaacagtat gacagtgatt cgctcacttt cggtggaggg
      301 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005019             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13510:8458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005019
VERSION     KCVT01005019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13510:8458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82544.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgg aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005020             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24631:7616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005020
VERSION     KCVT01005020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24631:7616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82545.1"
                     /translation="CQQGYGFPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          118 c          111 g           94 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcacgatc acttgccagg cgagtcaagg
      181 cattggcaat aatttaaatt ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 ctctaaggca tccagtttgc aaagtgggat tccctctcgg ctcagcggca gtggatctgg
      301 ggcggatttc actctcacca tcggcagcct gcagcctgaa gattttgcca cttactactg
      361 tcaacagggt tatggtttcc cgtggacatt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01005021             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11319:14556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005021
VERSION     KCVT01005021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11319:14556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82546.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005022             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5943:16383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005022
VERSION     KCVT01005022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5943:16383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82547.1"
                     /translation="CMQSLELPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          118 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcgtcca tctcctgtag gtctagtcag
      181 agcctcgtgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagcttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01005023             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18401:11674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005023
VERSION     KCVT01005023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18401:11674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82548.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatcaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggaat ttatttctgc atgcaagctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005024             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22947:17390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005024
VERSION     KCVT01005024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22947:17390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82549.1"
                     /translation="CQQGYNTPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          115 g           88 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattagc aggtggttag cctggtatca gcagaaacca gggaaagccc caagactcct
      241 gatctataag gcgtccactt tggcaagtgg ggtcccatca accttcagcg gcagtggatc
      301 tgggacggat tacactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag ggttacaata ccccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005025             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22360:10069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005025
VERSION     KCVT01005025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22360:10069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82550.1"
                     /translation="CQQYNSLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gatatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagttcctg
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattat
      361 tgtcaacagt ataatagttt accgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005026             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:17712:13515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005026
VERSION     KCVT01005026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17712:13515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82551.1"
                     /translation="CQQYYSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcgcc atcacttgtc gggcgagtca
      181 gggcattagt agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcatccattt tggaaggtga ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tattacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005027             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21170:12921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005027
VERSION     KCVT01005027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21170:12921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82552.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           94 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005028             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:5004:13816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005028
VERSION     KCVT01005028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:5004:13816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82553.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          118 c          100 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaacccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacaata taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gaa
//
LOCUS       KCVT01005029             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23459:7713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005029
VERSION     KCVT01005029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23459:7713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82554.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca cctcttaatt tatgacgttt ccacccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005030             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20784:19654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005030
VERSION     KCVT01005030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20784:19654"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..363
                     /note="immunoglobulin light chain variable region"
     V_region        44..363
     V_segment       44..327
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82555.1"
                     /translation="CQQYDSDPRTF"
     J_segment       331..363
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>368
                     /gene="IGKC"
BASE COUNT           88 a           99 c           97 g           84 t
ORIGIN      
        1 acatggggga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      121 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa cagtatgaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      361 caatcgag
//
LOCUS       KCVT01005031             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20112:10547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005031
VERSION     KCVT01005031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20112:10547"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82556.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccatactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005032             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14263:18112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005032
VERSION     KCVT01005032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14263:18112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..371
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82557.1"
                     /translation="CQQGYNTPWTF"
     J_segment       372..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           98 a          114 c          112 g           88 t
ORIGIN      
        1 catggggagt caggacacag catggacatg agggtccccg ctcagttcct ggggctcctg
       61 ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc atcgtccctg
      121 tctgcatctg taggagacaa agtcaccatc acttgccgag ccagtcaggg tattggcagg
      181 tggttagcct ggtatcagca gaaaccaggg aaagccccta gactcctgat ctataaggcg
      241 tccactttgg caagtggggt cccatcaacc ttcagcggca gtggatctgg gacggattac
      301 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg tcaacagggt
      361 tacaataccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005033             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12607:12456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005033
VERSION     KCVT01005033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12607:12456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..287
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82558.1"
                     /translation="CQQNSNWPLTF"
     J_segment       288..324
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>327
                     /gene="IGKC"
BASE COUNT           76 a           93 c           91 g           67 t
ORIGIN      
        1 acatgggagt gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca
       61 ccctctcctg cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac
      121 ctgggcaggc tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag
      181 gcaggttcag tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc
      241 ctgaagatgt tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg
      301 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005034             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9511:13713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005034
VERSION     KCVT01005034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9511:13713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82559.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcggttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01005035             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21210:10461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005035
VERSION     KCVT01005035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21210:10461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82560.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          121 c          114 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ctagtgggga tattgtgatg acccagactc
      121 cactgtcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga aacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaggttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01005036             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15483:12866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005036
VERSION     KCVT01005036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15483:12866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..402
                     /note="immunoglobulin light chain variable region"
     V_region        111..402
     V_segment       111..365
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <342..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82561.1"
                     /translation="CMQALEFPLTF"
     J_segment       366..402
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>405
                     /gene="IGKC"
BASE COUNT           90 a          101 c          114 g          100 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccatctcctg caggtctagt cagagcctct tggatagtga ggatggaaac acctatttgg
      181 aatggtacct gcagaagcca ggccagtctc cacagctctt gatttatgag gtttcctacc
      241 gggcctctgg agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga
      301 agatcagcag agtggaggct gaggatgttg gggtttatta ctgcatgcaa gctctagagt
      361 ttcctctcac tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01005037             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19848:11867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005037
VERSION     KCVT01005037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19848:11867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82562.1"
                     /translation="CQQYNSGPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          105 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtcttcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agagaccagg caaagccccg aggcccttga
      241 tctattacgc gtccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtggc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01005038             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16613:4159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005038
VERSION     KCVT01005038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16613:4159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82563.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccagt ttggaaagtg gggtcccatc aaggttcagc ggcggtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagacatca
      421 aacgag
//
LOCUS       KCVT01005039             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26797:16412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005039
VERSION     KCVT01005039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26797:16412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..407
                     /note="immunoglobulin light chain variable region"
     V_region        86..407
     V_segment       86..360
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82564.1"
                     /translation="CQQHNNYSPTF"
     J_segment       373..407
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>410
                     /gene="IGKC"
BASE COUNT          107 a          112 c          103 g           88 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccac cctccctgtc
      121 tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca ttagcaatga
      181 tttagtctgg tatcagctga aaccagggaa agccccgaag cccctgatct attacgcatc
      241 caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagatttcac
      301 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagcataa
      361 taattactct cccactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005040             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9858:18058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005040
VERSION     KCVT01005040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9858:18058"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82565.1"
                     /translation="CQQDFDWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           99 a          126 c          114 g           88 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc tcccaagctc
      241 ctcctctatg gtgcatccac cagggcctcc ggcatcccag gcaggttcag tgccagtggg
      301 tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt tggaatttat
      361 tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01005041             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13537:11273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005041
VERSION     KCVT01005041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13537:11273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82566.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcgtagcctg gtaccagcag aaacctgggc aggctcccag actcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01005042             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:25803:13970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005042
VERSION     KCVT01005042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25803:13970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82567.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          116 c          123 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatgtggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctttggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005043             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14381:17961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005043
VERSION     KCVT01005043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14381:17961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..270
                     /note="immunoglobulin light chain variable region"
     V_region        8..270
     V_segment       8..233
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82568.1"
                     /translation="CQQYNNDPPTF"
     J_segment       236..270
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>273
                     /gene="IGKC"
BASE COUNT           73 a           73 c           67 g           60 t
ORIGIN      
        1 acatgggcat cacttgtcgg gcgagtcagg gcattggcag tcatttagcg tggtatcagc
       61 agaaaccagg gaaagccccg aagcccttga tctattacgc atccaatttg gaaagtgggg
      121 tcccatcaag gttcagcggc agtggatctg ggacagactt cactctcacc atcagcagcc
      181 tgcagcctga agattttgca acttattact gtcaacagta taacaatgac cctcccactt
      241 tcggccccgg gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01005044             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11579:9281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005044
VERSION     KCVT01005044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11579:9281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82569.1"
                     /translation="CLQGYIDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          113 c          114 g           99 t
ORIGIN      
        1 acatggggag gggtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtcggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgatttttta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttgcaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcggcttatt
      361 actgtctaca gggttatatt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01005045             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21674:16518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005045
VERSION     KCVT01005045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21674:16518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82570.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          120 c          106 g           92 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttatttctg
      361 tcaacagcat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005046             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15532:12584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005046
VERSION     KCVT01005046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15532:12584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82571.1"
                     /translation="CLQFKSYPNSF"
     J_segment       385..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          101 a          116 c          107 g           99 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct aagctcctca
      241 tctatgctgc atccactttg gccggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagtt taaaagttac ccgaacagtt ttggccaggg gaccaaagtg gagatcaagc
      421 gag
//
LOCUS       KCVT01005047             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18948:18559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005047
VERSION     KCVT01005047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18948:18559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82572.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           87 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccaacaaaaa cctgggcagg ctcccaggct
      241 cctcatctat ggtgcatcca gcagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gacttcactc tcaccatcac catcctggag cctgaagatg ttgcagtcta
      361 tttttgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005048             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7608:15276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005048
VERSION     KCVT01005048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7608:15276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82573.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          115 c          103 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa agcaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01005049             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8350:6127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005049
VERSION     KCVT01005049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8350:6127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82574.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          122 c          121 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgtt ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01005050             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16134:17436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005050
VERSION     KCVT01005050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16134:17436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82575.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          113 g          109 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aagctccctg ctcagctcct
       61 ggggctgcta atgctctggc tctctggttc cagtggggat gttgtgatga cccagactcc
      121 attctccctg tccgttagcc ctggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttgaat agtgaagacg gaaacaccta tttggattgg tacctgcaga ggccgggcca
      241 gtctccacag cccttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatt aacagagtgg aggctgagga
      361 tgttgggatt tatatctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01005051             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9155:12667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005051
VERSION     KCVT01005051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9155:12667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..346
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82576.1"
                     /translation="CMQARDFPFTF"
     J_segment       347..384
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           83 a          104 c          110 g           90 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctgggtccat tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      121 gtcagagcct cttcgatagt gaggaaggaa acacctattt ggagtggtac ctgcagaggc
      181 caggccagtc tccacaggtc ttgatttatg gggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gagaatcagc agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aagctcgaga ctttccattc actttcggcc
      361 ccgggaccaa actggacatc aaacgag
//
LOCUS       KCVT01005052             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19325:11923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005052
VERSION     KCVT01005052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19325:11923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82577.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          108 c          108 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctctgg gggacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005053             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:28305:7747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005053
VERSION     KCVT01005053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:28305:7747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82578.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgccctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01005054             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7531:8868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005054
VERSION     KCVT01005054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7531:8868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82579.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag tctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005055             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20185:6674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005055
VERSION     KCVT01005055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20185:6674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82580.1"
                     /translation="CMQYRHIPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          114 g          111 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaagctccc tgctcagctc
       61 ctggggctgc taatgctctg gctctctggt tccagtgggg atgttgtgat gacccagact
      121 ccattctccc tgtccgttag ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttga atagtgaaga cggaaacacc tatttggatt ggtacctgca gaggccgggc
      241 cagtctccac agcccttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc atactgaaaa ttaacagagt ggaggctgag
      361 gatgttggga tttatatctg catgcaatat agacacattc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01005056             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22161:4848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005056
VERSION     KCVT01005056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22161:4848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82581.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          123 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcgcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005057             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5030:18125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005057
VERSION     KCVT01005057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5030:18125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82582.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacatgt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005058             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:11454:17785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005058
VERSION     KCVT01005058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11454:17785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82583.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          123 c          113 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005059             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25800:6108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005059
VERSION     KCVT01005059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25800:6108"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82584.1"
                     /translation="CQQHNNYSPTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          118 c          106 g           91 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccac
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttagcaatga tttagtctgg tatcagctga aaccagggaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagcataa taattactct cccactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005060             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8730:3939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005060
VERSION     KCVT01005060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8730:3939"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82585.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcagat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01005061             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18475:14605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005061
VERSION     KCVT01005061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18475:14605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82586.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccacagtg gagattaaac gag
//
LOCUS       KCVT01005062             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15954:6781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005062
VERSION     KCVT01005062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15954:6781"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82587.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          117 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg gccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005063             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21757:10904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005063
VERSION     KCVT01005063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21757:10904"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82588.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          123 c          116 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagcg tagcctggta ccagcaaaaa cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca gacagattca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005064             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10548:6405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005064
VERSION     KCVT01005064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10548:6405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82589.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          107 a          118 c          107 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagtcccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01005065             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20785:22616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005065
VERSION     KCVT01005065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20785:22616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82590.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 tactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005066             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9634:20186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005066
VERSION     KCVT01005066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9634:20186"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82591.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          125 c          116 g           86 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccaacaaaaa cctgggcagg ctcccaggct
      241 cctcatctat ggtgcatcca gcagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggaca gacttcactc tcaccatcac cagcctggag cctgaagatg ttgcagtcta
      361 tttttgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005067             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14701:5517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005067
VERSION     KCVT01005067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14701:5517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82592.1"
                     /translation="CQQHNTYPLTF"
     J_segment       388..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          112 a          118 c          103 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccagga gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gacataagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atgtattacg catccaattt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatat
      301 gggacacaat tcactctcac catcagcagc ctgcagcctg aagattttgc aagttattac
      361 tgtcaacagc ataatactta cccattgact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01005068             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19373:17216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005068
VERSION     KCVT01005068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19373:17216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82593.1"
                     /translation="CQHSFRTPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          117 c          110 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc gtcacttgca gggctagtga
      181 gagcgttagc accaaattac attggtatca acagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcgtccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggaacagat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttttta
      361 ctgtcagcat agttttcgta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005069             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7105:4708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005069
VERSION     KCVT01005069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7105:4708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82594.1"
                     /translation="CLQGYITPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          100 a          112 c          108 g           98 t
ORIGIN      
        1 acatgggaga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctccttctgc tctggctccc aggtgccaga tgtgacttcc agatgaccca gtctccatct
      121 tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 agcgattttt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg cctgatttat
      241 gctgcatcca gtttgcaaag tggggtcccg tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcggctta ttactgtcta
      361 cagggttata ttaccccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01005070             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8637:18852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005070
VERSION     KCVT01005070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8637:18852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82595.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          113 c          125 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ctagtgggga tgttgtgatg acccagattc
      121 cactctccct gccagtcatc cctggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gcccttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01005071             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10206:8758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005071
VERSION     KCVT01005071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10206:8758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82596.1"
                     /translation="CMQGLEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcgtgcaga tctagtcaga
      181 gtctcttgga tactgcggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactaaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005072             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13793:20751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005072
VERSION     KCVT01005072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13793:20751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82597.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          115 g          110 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caccggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct agagtttcct tggacgttcg gccaggggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005073             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20506:11535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005073
VERSION     KCVT01005073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20506:11535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82598.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          114 c          104 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cgttagcact tatttaaatt ggtatcagca gaaaccggga aaacccccta agtacctgat
      241 ctattatgca gaccgtttgg aaagtggagt cccatcaaga ttcagcggca gtggatctgg
      301 gacacaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aacagtttac ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005074             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:3748:9472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005074
VERSION     KCVT01005074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:3748:9472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82599.1"
                     /translation="FMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          115 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattacttca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005075             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13870:13823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005075
VERSION     KCVT01005075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13870:13823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82600.1"
                     /translation="CMQALEFPLTS"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcacttcc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005076             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21736:17002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005076
VERSION     KCVT01005076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21736:17002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82601.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005077             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15401:15759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005077
VERSION     KCVT01005077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15401:15759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..391
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82602.1"
                     /translation="CQQHNGYPPTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          112 a          123 c          111 g           95 t
ORIGIN      
        1 acatgggggg tcacacttca tgtaggagtc agaaccactc aggacacagc atggacatga
       61 gggtccccgc tcagctcctg gggctcctgc tgctctggct cccaggtgcc agatgtgaca
      121 tccagatgac ccagtctcca tcctccctgt ctgcatctgt aggagacaca gtcaccatca
      181 cttgtcgggc aagtcagggc attacgaatg atttagcctg gtatcaacag aaaccaggta
      241 aagccccgaa gcccctgatc tattacgcat ccaatttgga aagtggggtc ccatcaaggt
      301 tcagcggcag tggatctggg acagatttca ctctcaccat cagcagcctg cagcctgaag
      361 attttgcaac ttattattgt caacagcata atggataccc tccgacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01005078             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17890:11097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005078
VERSION     KCVT01005078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17890:11097"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82603.1"
                     /translation="CQQHDNAPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          115 c          116 g           86 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca gcatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcagcag catgacaatg ccccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005079             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18795:11387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005079
VERSION     KCVT01005079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18795:11387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82604.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          125 c          117 g          106 t
ORIGIN      
        1 acatgggggc tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgat aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcacc ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01005080             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22629:8310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005080
VERSION     KCVT01005080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22629:8310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82605.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005081             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24926:10094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005081
VERSION     KCVT01005081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24926:10094"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..368
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82606.1"
                     /translation="CQQGHTYPFTF"
     J_segment       378..414
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT           95 a          120 c          105 g           97 t
ORIGIN      
        1 atggggagtc tcagtcagga cacagcatgg acatgagggt ccccgctcag ctccttgggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacgcag tctccatcct
      121 ccctgtccgc atctgtagga gacacagtca cgatcacttg ccaggcgagt caaggcattg
      181 gcaagacttt aagttggtat cagcagaaac cagagaaagc ccctaatctc ctgatctata
      241 gggcatccag tttgcaaggt ggggttccct ctcggttcag cggcagtgga tctgggacgg
      301 atttcactct caccatcagc agcctgcagc ctgaagattt tgccacttat tactgtcaac
      361 agggtcatac ttaccctttc actttcggcc ccgggaccaa actggatatc aaacgag
//
LOCUS       KCVT01005082             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7186:14213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005082
VERSION     KCVT01005082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7186:14213"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82607.1"
                     /translation="CQQHNGNPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          118 c          106 g           88 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggaaaccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01005083             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:8438:7408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005083
VERSION     KCVT01005083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8438:7408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..379
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82608.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          125 c          112 g           86 t
ORIGIN      
        1 acatggggga ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgctga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcagc aacttagcct ggtaccagca gagacctggg cagtctccca gactcctcat
      241 ctatggtgca tccaacaggg ccactggcat cccaggcagg ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gatgttgcac tttattattg
      361 tcagcagaac agtaactggc ctctcacttt cggtggaggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005084             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20414:13529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005084
VERSION     KCVT01005084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20414:13529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82609.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005085             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:25505:9056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005085
VERSION     KCVT01005085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:25505:9056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82610.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattaca catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005086             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4928:17277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005086
VERSION     KCVT01005086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4928:17277"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82611.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005087             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12696:14444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005087
VERSION     KCVT01005087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12696:14444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    136..456
                     /note="immunoglobulin light chain variable region"
     V_region        136..456
     V_segment       136..419
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <396..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82612.1"
                     /translation="CQQNSNWPLTF"
     J_segment       420..456
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>459
                     /gene="IGKC"
BASE COUNT          106 a          136 c          126 g           91 t
ORIGIN      
        1 acatggggag cccatatgaa tgcctgggtc agagctctgg ggaggaactg ctcagttagg
       61 acccagaggg aaccatggaa gccccagcac agcttctctt cctcctgctg ctctggctcc
      121 cagataccac cggacaaata gtgctgacgc agtctccagc caccctgtcc ttgtctccag
      181 gagaaagagc caccctctcc tgcagggcca gtcagagtgt cagcagcagc ctagcctggt
      241 accagcagaa acctgggcag gctcccagac tcctcatctt tggtgcatcc aacagggcca
      301 ctggcatccc aggcaggttc agtggcagtg ggtctgggac agagttcact ctcaccatca
      361 gcagcctgga gcctgaagat gttgcacttt attattgtca gcagaacagt aactggcctc
      421 tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005088             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:25498:7219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005088
VERSION     KCVT01005088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25498:7219"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82613.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          118 c          105 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcac
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005089             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17350:11006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005089
VERSION     KCVT01005089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17350:11006"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82614.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagagtcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgagatttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcacagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005090             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23616:3615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005090
VERSION     KCVT01005090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23616:3615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82615.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005091             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9392:11344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005091
VERSION     KCVT01005091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9392:11344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82616.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          122 c          115 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcacc agcagcttag cctggtatca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005092             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7631:11398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005092
VERSION     KCVT01005092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7631:11398"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82617.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagaggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005093             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17730:17736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005093
VERSION     KCVT01005093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17730:17736"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    47..368
                     /note="immunoglobulin light chain variable region"
     V_region        47..368
     V_segment       47..331
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82618.1"
                     /translation="CQQHDDSPRTF"
     J_segment       333..368
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           96 a          100 c           95 g           80 t
ORIGIN      
        1 acatgggggg gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac
       61 ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgcacagc
      121 cagtcagggt attaataact ggttggcctg gtatcaacag aaaccaggaa aagcccctaa
      181 actcctgatc tatagggcat ccaatttgga cacaggggtc ccatcgaggt tcggtggaag
      241 tggatctggg acagatttca ctctcaccat cagcagcctg cagcctgaag atatcgcaac
      301 atattactgt caacagcatg atgattcccc tcggacgttc ggccaaggga ccaaggtgga
      361 aatcaaacga g
//
LOCUS       KCVT01005094             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10693:5799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005094
VERSION     KCVT01005094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10693:5799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82619.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactact aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01005095             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:9666:13036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005095
VERSION     KCVT01005095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9666:13036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82620.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcgttaga agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatttattat gcatccattt tggaaggtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcagcag tataacagtg acccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01005096             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5632:10088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005096
VERSION     KCVT01005096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5632:10088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..383
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82621.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       389..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          103 a          113 c          112 g          102 t
ORIGIN      
        1 acatggggga gttagaccca gtctggacgc agcatggaca tcagggtcct cgctcagctt
       61 ctcgggctcc tgctgctctg gctcccaggt gccagatgtg acactcagtt gacccagtct
      121 ccatcctccc tgtctgtatc tgtaggagac agagtcacca tcacttgtcg gacaagtcag
      181 gacattagca gttatttagc ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctataagg cgtccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaggctg aagattttgc agtttattac
      361 tgtcaacagc gtattggtta cccgtacatg tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01005097             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19534:15844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005097
VERSION     KCVT01005097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19534:15844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..281
                     /note="immunoglobulin light chain variable region"
     V_region        8..281
     V_segment       8..247
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82622.1"
                     /translation="CQQYDSDPYSF"
     J_segment       248..281
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>288
                     /gene="IGKC"
BASE COUNT           78 a           66 c           81 g           63 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gtcgggcgag tcagggcatt aggagttatt
       61 tagcgtggta tcagcagaaa ccagggaaag ccccgaaggc cttgatctat tacacatcca
      121 ttttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag cagcctgcag cctgaggatt ttgcaactta ttactgtcaa cagtatgaca
      241 gtgacccgta cagttttggc caggggacca gagtggagat ccaacgag
//
LOCUS       KCVT01005098             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12157:10561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005098
VERSION     KCVT01005098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12157:10561"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82623.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005099             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15622:13757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005099
VERSION     KCVT01005099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15622:13757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82624.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          117 c          104 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gatgattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01005100             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24687:13055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005100
VERSION     KCVT01005100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24687:13055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82625.1"
                     /translation="CMQALDFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          120 c          123 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagtctct tggatagtga ggatggaaac acttacttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccgacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagact ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01005101             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19207:17767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005101
VERSION     KCVT01005101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19207:17767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82626.1"
                     /translation="CQQHNTYPYTF"
     J_segment       383..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          105 a          119 c          105 g           94 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattactaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tcttttacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taatacttac ccgtacactt ttggccaggg gaccaaggtg gagatcatac
      421 gag
//
LOCUS       KCVT01005102             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19071:13824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005102
VERSION     KCVT01005102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19071:13824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82627.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          113 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01005103             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23840:6684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005103
VERSION     KCVT01005103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23840:6684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..293
                     /note="immunoglobulin light chain variable region"
     V_region        8..293
     V_segment       8..255
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82628.1"
                     /translation="CQQYDSDPFTF"
     J_segment       258..293
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>296
                     /gene="IGKC"
BASE COUNT           77 a           70 c           83 g           66 t
ORIGIN      
        1 acatggggca tctgtaggag acagagtcag catcacttgt cgggcgagtc agggcattcg
       61 cagttattta gcgtggtatc agcagagacc agggaaagcc ccgaagccct tgatctatta
      121 cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga
      181 attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt actgtcaaca
      241 gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagagatca aacgag
//
LOCUS       KCVT01005104             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5313:15109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005104
VERSION     KCVT01005104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5313:15109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..426
                     /note="immunoglobulin light chain variable region"
     V_region        106..426
     V_segment       106..388
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82629.1"
                     /translation="CQQYNSDPYSF"
     J_segment       389..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          112 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggat gcaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctag gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggcg
      181 agtcagggca ttagaagtta tttagcgtgg tatcagcaga aaccaggaaa agccccgaag
      241 gccttgatct attacgcatc cattttagaa agtgcggtcc catcaaggtt cagcggcagt
      301 ggatctggga cagaattcac ctcaccatca gcagcctgca gtctgacgat tttgcaactt
      361 attactgtca acagtataac agtgacccgt acagttttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01005105             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:25148:10605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005105
VERSION     KCVT01005105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25148:10605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..357
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82630.1"
                     /translation="CQQHNGYPPMF"
     J_segment       373..404
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT          100 a          114 c          105 g           88 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tcctgctgct
       61 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
      121 atctgtagga gacacagtca ccatcacttg tcgggcaagt cagggcatta ccaatgattt
      181 agcctggtat cagcagagac cagggaaagc cccgaagccc ctgatctatt acgcatccaa
      241 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct
      301 caccatcagc agcctgcagc ctgaagattt tgcaacttat tattgtcaac agcataatgg
      361 ataccctccg atgttcggcc aagggaccag ggtggaaatc aaacgag
//
LOCUS       KCVT01005106             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:27224:15306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005106
VERSION     KCVT01005106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27224:15306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82631.1"
                     /translation="CQQGDSYPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          113 c          114 g           94 t
ORIGIN      
        1 acatggtggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgtccca
      121 gtctccttcc tccctgtctg catctgtggg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt agagattatt taaattggta tcagcagcaa ccggggaaag cccctaaact
      241 cctgatgtat tatgcaaaca gtctggcaag tggagtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcagtc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagggtgaca gttatcctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01005107             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:23325:12002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005107
VERSION     KCVT01005107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23325:12002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82632.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          114 c          109 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtag gtatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattttgc aaatcgtttg ggaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacctga ggattttgcg acttattatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01005108             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13824:8844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005108
VERSION     KCVT01005108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13824:8844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82633.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005109             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:27120:10170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005109
VERSION     KCVT01005109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:27120:10170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82634.1"
                     /translation="CQKYISSPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          130 c          105 g           91 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caacttatat tgactcagtc
      121 tccagccacc ctgtctctgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccaggctcct
      241 cctctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtatatta
      361 ctgtcagaaa tatattagct ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01005110             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17283:10988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005110
VERSION     KCVT01005110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17283:10988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82635.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          123 c          112 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac agattcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005111             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17938:10847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005111
VERSION     KCVT01005111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17938:10847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82636.1"
                     /translation="CLQGDTTPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          113 g           96 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atctatgctg catccagttt ggagagcggg gtcccatcaa ggttcagcgg cagtggattt
      301 gggacagaat tcactctcac tattagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gtgatactac cccattcact ttcggcgggg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005112             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7792:7059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005112
VERSION     KCVT01005112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7792:7059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82637.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          123 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgaaga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005113             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10924:17677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005113
VERSION     KCVT01005113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10924:17677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82638.1"
                     /translation="CMQALQTPYTF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgcct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcacc cttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgaa tagtaatgga tacaactatt tgagttggta ccttcagaag ccaggccagt
      241 ctccacatct gctgatctat tatggctcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgacaatcag cagggtggag gctgaggacg
      361 tagggattta ttactgcatg caagctctac aaactccgta cacttttggc caggggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01005114             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14743:7806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005114
VERSION     KCVT01005114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14743:7806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..350
                     /note="immunoglobulin light chain variable region"
     V_region        11..350
     V_segment       11..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <290..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82639.1"
                     /translation="CMQALEFPLTF"
     J_segment       313..350
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>353
                     /gene="IGKC"
BASE COUNT           82 a           87 c          101 g           83 t
ORIGIN      
        1 acatgggggg gacattgtga tgacccagag tccactctcc ctgtccgtca cccttggaga
       61 gccggcctcc atctcctgca ggtctagtca gagcctcttg gatagtgagg atggaaacac
      121 ctatttggaa tggtacctgc agaagccagg ccagtctcca cagctcttga tttatgagat
      181 ttccaaccgg gcctctggag tcccagacag gttcagtggc agtgggtcag acactgattt
      241 cacactgaaa atcagcacag tggaggctga ggatgttggg gtttattact gcatgcaagc
      301 tctagagttt ccgctcactt tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005115             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22509:6169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005115
VERSION     KCVT01005115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22509:6169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..364
                     /note="immunoglobulin light chain variable region"
     V_region        44..364
     V_segment       44..327
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82640.1"
                     /translation="CLQYKSYPFTF"
     J_segment       328..364
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>368
                     /gene="IGKC"
BASE COUNT           91 a           95 c           88 g           94 t
ORIGIN      
        1 acatgggggg ctcttgctgc tctggctccc aggtgccaga tgtgacatcc aactgactca
       61 gtctccatct tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag
      121 tcagggtatt agtagttatt taaattggtt tcagcagaaa acagggaagg cccctaagct
      181 cctgatctat gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atttgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcta cagtataaaa gttacccatt cactttcggc cccgggacca aactggacat
      361 caaaggag
//
LOCUS       KCVT01005116             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13525:15147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005116
VERSION     KCVT01005116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13525:15147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82641.1"
                     /translation="CQQGSPFPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          112 c          107 g           96 t
ORIGIN      
        1 acatggggat gagcaaaact gacaagtcaa ggcaggaaga tgttgtctcc atcacaactc
       61 attgggtttc tgctgctctg ggttccagcc tccaagggtg aaattgtgct gactcagtct
      121 ccagcctttc ggtctgtgac tctaaaggag aaagtcacca tcacctgcca ggccagtcag
      181 aacattggta ctagcttaca ctggtaccag cagaaaccgg atcagtctcc aaagctcctc
      241 atcaagtatg cttcccagtc catctcaggg gtcccctcaa ggttcagtgg cagtggatct
      301 gggacagatt tcaccctcac catcaatagc ctggaagctg aagatgctgc gacgtattac
      361 tgtcagcagg gaagtccttt cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005117             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9355:5309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005117
VERSION     KCVT01005117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9355:5309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82642.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acctattact
      361 gtcaacagta tgacagtgat ccgttcactt tcggtggggg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01005118             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20960:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005118
VERSION     KCVT01005118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20960:7995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..330
                     /note="immunoglobulin light chain variable region"
     V_region        8..330
     V_segment       8..293
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <270..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82643.1"
                     /translation="CMQALEFPLTF"
     J_segment       294..330
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>333
                     /gene="IGKC"
BASE COUNT           74 a           83 c           95 g           81 t
ORIGIN      
        1 acatggggac tccactctcc ctgcccgtca ctcttggaga gccggcctcc atctcctgca
       61 ggtctagtca gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc
      121 agaagccagg ccagtctcca cagctcttga tttatgaggt ttcctaccgg gcctctggag
      181 tcccagacag gttcagtggc agtgggtcag acactgattt cacactgaag atcagcagag
      241 tggaggctga ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt
      301 tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005119             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9134:8984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005119
VERSION     KCVT01005119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9134:8984"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82644.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          117 c          107 g           87 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcacagcc agccacgata
      181 taaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcgaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcagcatc agcagcctgc agcctgaaga tttcgcaaca tatttctgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01005120             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12906:6776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005120
VERSION     KCVT01005120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12906:6776"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82645.1"
                     /translation="CLQSKNSPWSF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          116 c          115 g          100 t
ORIGIN      
        1 acatgggggc agcctctagt tcagctctca gaaatggggt cctggtctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggctgcagt ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accatcacct gcagagccag tgagagtgtc
      181 agtgcctttg gaataagcct cattcactgg tatcaacaga aaccaggaca acctcctaaa
      241 ctcctgattt accaagcaat caataaggag actggggtcc cagccaggtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aacctgacga tggtgcagat
      361 tattactgtc tgcagagtaa gaattctccg tggtcgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01005121             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5588:8252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005121
VERSION     KCVT01005121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5588:8252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82646.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa gtgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttaatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005122             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7334:15795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005122
VERSION     KCVT01005122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7334:15795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..395
                     /note="immunoglobulin light chain variable region"
     V_region        101..395
     V_segment       101..357
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82647.1"
                     /translation="CQQYNSDPFTF"
     J_segment       358..395
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>398
                     /gene="IGKC"
BASE COUNT          105 a          109 c           95 g           89 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaact atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatcagttt tggaaagtgg atctgggaca gaattcactc tcaccatcag
      301 cagtctgcag cctgaggatt ttgcaactta ttactgtcaa cagtataaca gtgacccatt
      361 cactttcggc cccgggacca aactggatac caaacgag
//
LOCUS       KCVT01005123             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13453:3852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005123
VERSION     KCVT01005123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13453:3852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..381
                     /note="immunoglobulin light chain variable region"
     V_region        143..381
     V_segment       143..344
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <321..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82648.1"
                     /translation="CMQGLEFPWTF"
     J_segment       345..381
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>384
                     /gene="IGKC"
BASE COUNT           84 a          103 c          108 g           89 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagaca cctatttgga gtggtacctg cagaagccag
      181 gccagtctcc acagctcttg atttatgagg tgtccaaccg ggcctctgga gtcccagaca
      241 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      301 aggatgttgg ggtttattac tgcatgcaag gtctagagtt tccttggacg ttcggccaag
      361 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005124             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14541:12835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005124
VERSION     KCVT01005124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14541:12835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82649.1"
                     /translation="CMQALEFPYSF"
     J_segment       276..312
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           72 a           80 c           87 g           76 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cacaactctt gatttatgac gtttccagcc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctagagt ttccctacag ttttggccag gggaccaaag
      301 tggagatcaa acgag
//
LOCUS       KCVT01005125             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5663:3927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005125
VERSION     KCVT01005125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5663:3927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82650.1"
                     /translation="CQQYNNLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          111 c          106 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacctt cagaagaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctcatcta
      241 ttatgtgaat cgtttggaaa gtggggtccc atcaaggttc agcgacagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat aatttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01005126             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7623:23274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005126
VERSION     KCVT01005126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7623:23274"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82651.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagat actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01005127             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20393:4127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005127
VERSION     KCVT01005127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20393:4127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82652.1"
                     /translation="CQQHDNMPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          115 c          116 g           87 t
ORIGIN      
        1 acatgggggg agtcagtcgc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgca gagccagtca
      181 gggtattagc aactggttgg cctggtatca acagaaacca gggaaagccc ctaagctcct
      241 gatctatagg gcatggaatc tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 cgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg caacatatta
      361 ctgtcaacag catgataata tgccgctcac tttcggtgga gggaccaagg tggacatcaa
      421 acgag
//
LOCUS       KCVT01005128             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:5532:10066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005128
VERSION     KCVT01005128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5532:10066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82653.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          121 c          118 g           94 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcccgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01005129             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14693:10496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005129
VERSION     KCVT01005129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14693:10496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..389
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82654.1"
                     /translation="CMQALEFPLTF"
     J_segment       390..426
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           88 a          117 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ttggagtggc acctgcagaa gccaggccag tctctacagc
      241 tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc agtggcagtg
      301 ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat gttggggttt
      361 atttctgcat gcaggctcta gagtttcctc tcactttcgg cggagggacc aaggtggaga
      421 tcaaacgag
//
LOCUS       KCVT01005130             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22545:7000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005130
VERSION     KCVT01005130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22545:7000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82655.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg ttcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005131             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15429:17065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005131
VERSION     KCVT01005131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15429:17065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82656.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggca gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01005132             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18831:6755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005132
VERSION     KCVT01005132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18831:6755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82657.1"
                     /translation="CMQGLEFPPTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          123 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggcga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtggtgat ggaaacacct atttggaatg gttcctccag aggccaggcc
      241 agtctccaca cctcttgatt tatggggctt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc tccgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005133             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21935:13329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005133
VERSION     KCVT01005133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21935:13329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82658.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccagc agaaacctgg gcaggctccc aggctcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca gtttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005134             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22311:12596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005134
VERSION     KCVT01005134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22311:12596"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82659.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005135             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13015:7332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005135
VERSION     KCVT01005135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13015:7332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82660.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          115 c          103 g           96 t
ORIGIN      
        1 acatggggag tcagacctag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaactat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01005136             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15544:9320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005136
VERSION     KCVT01005136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15544:9320"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..390
                     /note="immunoglobulin light chain variable region"
     V_region        81..390
     V_segment       81..364
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82661.1"
                     /translation="CQQYDTDPFTF"
     J_segment       367..390
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>392
                     /gene="IGKC"
BASE COUNT           91 a          109 c          103 g           89 t
ORIGIN      
        1 acatggggga cagcatggac atgagggtcc ccgctcagct cctaggactc ctgctgctct
       61 gtctcccagg tgccaaatgt gacatccaga tgacccagtc tccatcctcc ctgtctgcat
      121 ctgtaggaga cagagtcacc atcacttgtc gggcgagtca gggcattcgc agttatttag
      181 cgtggtatca gcagaaaccg gggaaagccc cgaagccctt gatctattac gcgtccactt
      241 tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca
      301 ccatcagcag cctgcagcct gaagattttg caacttatta ctgtcaacag tatgacactg
      361 acccgttcac tttcggtgga gggaccaagg ag
//
LOCUS       KCVT01005137             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21318:6538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005137
VERSION     KCVT01005137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21318:6538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82662.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          119 c          117 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgccttg gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatccctga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggattttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005138             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:21513:14023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005138
VERSION     KCVT01005138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21513:14023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82663.1"
                     /translation="CQQYNSLPLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          108 c          109 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctctg ggggacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcagata tttaaattgg tatcagcaga aaccggggaa agcccctaag ttcctgatct
      241 attatgtaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcaact tattattgtc
      361 aacagtataa tagtttaccg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005139             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19860:9359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005139
VERSION     KCVT01005139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19860:9359"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    47..368
                     /note="immunoglobulin light chain variable region"
     V_region        47..368
     V_segment       47..331
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82664.1"
                     /translation="CQQGNSNPLTF"
     J_segment       332..368
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           92 a           90 c          100 g           89 t
ORIGIN      
        1 acatgggggg gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgtc
       61 ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgccgggc
      121 aagtcagggc attagtagtt atttaaattg gtatcagcag agaccgggga aagcccctaa
      181 gctcctgatc tattatgcaa agagtttggc aagtggggtc ccatcaaggt tcagcggcag
      241 tggatctggg acagaattca ctctcacaat cagtagcctg cagcctgaag attttgcaac
      301 ttattactgt caacagggta atagtaatcc tctcactttc ggcggaggga ccaaggtgga
      361 gatcaaacga g
//
LOCUS       KCVT01005140             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12557:8840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005140
VERSION     KCVT01005140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12557:8840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..382
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82665.1"
                     /translation="CYQYTGGYTF"
     J_segment       383..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           92 a          127 c          112 g           88 t
ORIGIN      
        1 acatgggggg ctgctaggtt agtacccaga gggaaccatg gaagccccag ctcggcttct
       61 ctgccttctg ctactctggc tcccaggtac caccggacaa gttatattga cacagtctcc
      121 agccaccctg tctttgtctc caggggagag agccactctc tcctgcaggg ccagtcagag
      181 tgttagtact tacttagcct ggtaccagca gaaacctggg caggctccca ggctcctcat
      241 ccacagtgcg tccagcaggg ccactggcat cccagacagg ttcagtggca gcgggtctgg
      301 gacagagttc accctcacca tcagcagcct ggagcctgaa gatgttggag tttatcactg
      361 ctatcagtat accggcggat acactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01005141             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9074:11050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005141
VERSION     KCVT01005141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9074:11050"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82666.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtggggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggggtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01005142             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16616:13426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005142
VERSION     KCVT01005142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16616:13426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82667.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccaaca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005143             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10035:9397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005143
VERSION     KCVT01005143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10035:9397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82668.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaagtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggactttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01005144             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24036:17987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005144
VERSION     KCVT01005144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24036:17987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82669.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          124 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgttctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactgtccc tgcccgtcac ccttggagag ccggcctcca tctcctgtgg gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005145             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22140:12513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005145
VERSION     KCVT01005145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22140:12513"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82670.1"
                     /translation="CQQGYSFPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           96 a          120 c          106 g          101 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcag tagtttaagt tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctttagggc atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcatc atcagcagcc tccagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagtttc cccttcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01005146             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:8588:20771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005146
VERSION     KCVT01005146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8588:20771"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..249
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82671.1"
                     /translation="CQHSFRTPYSF"
     J_segment       250..287
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           77 a           70 c           76 g           67 t
ORIGIN      
        1 acatggggta ggagacagag tcaatgtcac ttgcagggct agtgagagcg ttagcaccaa
       61 attacattgg tatcagcaga aaccagggaa agcccctaag ctcctgatct ttgctgcgtc
      121 cactttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggaa cagatttcac
      181 tctcaccatc agcagcctgc agcctgaaga tgtcgcaact ttttactgtc agcatagttt
      241 tcgtaccccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01005147             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24222:2239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005147
VERSION     KCVT01005147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24222:2239"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82672.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005148             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16664:11242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005148
VERSION     KCVT01005148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16664:11242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82673.1"
                     /translation="CYQHSRGWAF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           96 a          123 c          115 g           84 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaag ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccactctct cctgcagggc cagtgagaat
      181 gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccagcagggc cactgacatc ccagacaggt tcagtggcag tgggtctcgg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttggagt ctattactgc
      361 tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01005149             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16281:12125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005149
VERSION     KCVT01005149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16281:12125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..374
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82674.1"
                     /translation="CQQHDDSPRTF"
     J_segment       376..411
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT          108 a          113 c          108 g           85 t
ORIGIN      
        1 acatggggga gacaggacac agcatggaca cgagggtccc cgctcagctc ctggggctcc
       61 tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc
      121 tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag gatattaaca
      181 actggttggc ctggtatcaa cagaaaccag ggaaagcccc taaggtcctg atctataggg
      241 catccatttt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct gggacagatt
      301 tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac tgtcaacagc
      361 atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005150             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24308:17204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005150
VERSION     KCVT01005150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24308:17204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82675.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc actcaccttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01005151             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12134:15951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005151
VERSION     KCVT01005151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12134:15951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82676.1"
                     /translation="CHQGNNIPGTF"
     J_segment       391..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          110 a          114 c          106 g           99 t
ORIGIN      
        1 acatggggac gtttagcctg tgacagggct cagctaacat aatggatttt caggctcaaa
       61 ttttcatctt ccttctgctc agtgtcacag tgtccaatgg agaaattgtg ctgacccagt
      121 ctccaacctc catggctgtc tcccaaggag aaagagtcac catctcctgc acggccagct
      181 caagtgtaag cactagctac ttgcactggt accaacagaa gccaggattc cctccaaggc
      241 ttcttgtcta tagaacatca agtctggctt ctggggtccc agccaggttc agtggcagcg
      301 gttctgggac ctcttacacg ctcacaatca gcagcatgga ggctgaagat gctgcaaact
      361 attactgtca ccaggggaat aacattccgg ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01005152             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11288:17988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005152
VERSION     KCVT01005152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11288:17988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82677.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          125 c          116 g           85 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005153             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:6047:7652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005153
VERSION     KCVT01005153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6047:7652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..309
                     /note="immunoglobulin light chain variable region"
     V_region        110..309
     V_segment       110..273
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <251..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82678.1"
                     /translation="CMQSLDFPLTF"
     J_segment       274..309
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>314
                     /gene="IGKC"
BASE COUNT           67 a           78 c           89 g           80 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg gccagtctcc
      121 acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca ggttcagtgg
      181 cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      241 ggtttattac tgcatgcagt ctctagattt tccgctcact ttcggtggag ggaccaaggt
      301 ggagatcaat cgag
//
LOCUS       KCVT01005154             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15634:12911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005154
VERSION     KCVT01005154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15634:12911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82679.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctatgactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcgtc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01005155             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17734:6440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005155
VERSION     KCVT01005155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17734:6440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82680.1"
                     /translation="CQQYNSLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          108 c          108 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gatatttaaa ttggtatcaa cagaaaccgg ggaaagcccc taagttcctg
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattat
      361 tgtcaacagt ataatagttt accgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005156             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18245:13056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005156
VERSION     KCVT01005156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18245:13056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82681.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005157             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19681:15899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005157
VERSION     KCVT01005157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19681:15899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82682.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tgtctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005158             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13940:14285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005158
VERSION     KCVT01005158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13940:14285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..285
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82683.1"
                     /translation="CQQYDSFPLTF"
     J_segment       288..323
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>326
                     /gene="IGKC"
BASE COUNT           82 a           83 c           80 g           81 t
ORIGIN      
        1 acatgggcag atgacccagt ctccatcctc cctgtctgct tctgtgggag acagagtcac
       61 catcacttgc cgggcaagtc aggacattag taggtattta aattggtatc agcagaaacc
      121 ggggaaagcc cctaaggtcc tgatctattt tgcaaatcgt ttgggaagtg gggtcccatc
      181 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcaaca gcctgcaacc
      241 tgaggatttt gcgacttatt attgtcagca gtatgatagt ttccccctca ctttcggccc
      301 cgggaccaaa ctggatatca aacgag
//
LOCUS       KCVT01005159             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24315:19945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005159
VERSION     KCVT01005159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24315:19945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82684.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat cttctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005160             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:24025:11413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005160
VERSION     KCVT01005160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24025:11413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82685.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          117 c          111 g           88 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcaggatatt aacaactggt tggcctggta tcaacaaaaa ccagggaaag cccctaaggt
      241 cctgatctat agggcatcca ttttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01005161             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:9257:12550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005161
VERSION     KCVT01005161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9257:12550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82686.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agagccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005162             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22614:8040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005162
VERSION     KCVT01005162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22614:8040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82687.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcgttcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaactgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg actcgctcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01005163             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10807:6708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005163
VERSION     KCVT01005163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10807:6708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82688.1"
                     /translation="CQQHADSPRTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>420
                     /gene="IGKC"
BASE COUNT          106 a          117 c          111 g           86 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggta
      181 ttagcaactg gttggcctgg tatcaacaga gaccagggaa agcccctaag gtcctgatct
      241 ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaacc ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tttcgcaaca tattactgtc
      361 aacagcatgc tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaaggag
//
LOCUS       KCVT01005164             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14831:15857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005164
VERSION     KCVT01005164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14831:15857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82689.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          123 c          117 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gacatcaaac gag
//
LOCUS       KCVT01005165             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18094:6962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005165
VERSION     KCVT01005165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18094:6962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82690.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg ctccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005166             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:8304:20790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005166
VERSION     KCVT01005166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8304:20790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..425
                     /note="immunoglobulin light chain variable region"
     V_region        86..425
     V_segment       86..388
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82691.1"
                     /translation="CMQALEFPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           94 a          116 c          114 g          104 t
ORIGIN      
        1 acatgggtca ggtcaccttc tcacaatgag gctccctgct cagctcctgg gactgctaat
       61 gctctggctc cctggatcca ctggggacat tgtgctgacc cagactccac tctccctgcc
      121 cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagaacc tcttggatag
      181 tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt ctccacagct
      241 cttgatttat gaggtttcca atcgggcctc tggagtccca gacaggttca gtggcagtgg
      301 gtcagacact gatttcacac tgaaaatcag cagagtggag cctgaggatg ttggggttta
      361 ttactgcatg caagctctag aatttcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005167             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14941:20761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005167
VERSION     KCVT01005167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14941:20761"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82692.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          125 c          110 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacgtgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat caacagagtg gaggctgagg
      361 atcttggaat ttattactgc atgcaagctc tagaatttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005168             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18442:13865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005168
VERSION     KCVT01005168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18442:13865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82693.1"
                     /translation="CLQYRSYPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          111 c          107 g           97 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 ggatattagc agttatttaa attggtttca gaagaaacca gggaaagccc ctaagctcct
      241 gatccaagct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tatagaagtt acccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005169             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16142:9335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005169
VERSION     KCVT01005169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16142:9335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    48..369
                     /note="immunoglobulin light chain variable region"
     V_region        48..369
     V_segment       48..331
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82694.1"
                     /translation="CEQYNSLPYTF"
     J_segment       332..369
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>372
                     /gene="IGKC"
BASE COUNT          103 a           94 c           87 g           88 t
ORIGIN      
        1 acatggggag gagtcagact cagctctggc tcccaggtgc cagatgtgac attcagatga
       61 cccagtctcc atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg
      121 caagtcagga cattaacgtt tatttaaatt ggtatcacca gaaaccgggg aaagccccta
      181 agctcctgat ctattataca aaccgtttgg aaactggggt cccatcaagg ttcagcggca
      241 gtggatctgg gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa
      301 cttattactg tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg
      361 agatcaaacg ag
//
LOCUS       KCVT01005170             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14110:9110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005170
VERSION     KCVT01005170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14110:9110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82695.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          120 c          107 g           88 t
ORIGIN      
        1 acatggggca gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttaccaatga tttagcctgg tatcagcaga gaccagggaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01005171             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16943:7627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005171
VERSION     KCVT01005171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16943:7627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    148..359
                     /note="immunoglobulin light chain variable region"
     V_region        148..359
     V_segment       148..321
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82696.1"
                     /translation="CQQHDNSPWTF"
     J_segment       322..359
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           92 a          101 c           96 g           73 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagaccaggg aaggccccta agctcctgat
      181 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      241 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      301 tcaacagcat gataattccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      361 ag
//
LOCUS       KCVT01005172             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16837:12052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005172
VERSION     KCVT01005172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16837:12052"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82697.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggatt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005173             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5169:8522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005173
VERSION     KCVT01005173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5169:8522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82698.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005174             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19000:14588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005174
VERSION     KCVT01005174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19000:14588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82699.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagtcggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01005175             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20977:8783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005175
VERSION     KCVT01005175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20977:8783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82700.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          118 c          104 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcac ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01005176             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10615:9774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005176
VERSION     KCVT01005176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10615:9774"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82701.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcttccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttttttaaa ttggtatcag cagaaaccgg ggaaagcccc taaggccctg
      241 atctattatg caaaccggtt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaatctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt agagatcaaa
      421 cgag
//
LOCUS       KCVT01005177             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21535:17346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005177
VERSION     KCVT01005177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21535:17346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..416
                     /note="immunoglobulin light chain variable region"
     V_region        101..416
     V_segment       101..379
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82702.1"
                     /translation="CQQDFDWPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          125 c          112 g           84 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctccgg gggaaagagc caccctctcc tgcagggcca gtcagagtgt
      181 tggcaacacc ttaacctggt accagcacaa acctgggcag gctcccaagc tcctcctcta
      241 tggtgcatcc accagggcct ccggcatccc aggcaggttc agtgccagtg ggtctggaac
      301 agagtttact ctcaccatca gcagcctgga gcctgaagat gttggaattt attactgtca
      361 gcaggatttt gactggcctc cgacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005178             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22008:13409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005178
VERSION     KCVT01005178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22008:13409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..381
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82703.1"
                     /translation="CQQVYSNPAF"
     J_segment       384..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          111 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggccctg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgat atccaggtga cccagtctcc
      121 atctgccttg tctgcatctg taggagacag agtcaccatc tcttgccggg caagtcagaa
      181 catttatagg aatttagcgt ggtatcagca gaaaccaggg aaagccccta agctcctgat
      241 ctttgctgca tccagattgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcaacct acagcctgaa gattctgcaa tttattactg
      361 tcaacaggtt tatagtaacc cggcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005179             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8290:17939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005179
VERSION     KCVT01005179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8290:17939"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82704.1"
                     /translation="CMQSLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccagac
      241 cagtctctag agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005180             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:3412:8046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005180
VERSION     KCVT01005180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3412:8046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82705.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005181             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19570:10790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005181
VERSION     KCVT01005181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19570:10790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82706.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          125 c          121 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctttg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01005182             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13729:13762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005182
VERSION     KCVT01005182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13729:13762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82707.1"
                     /translation="CQQDFDWPPTF"
     J_segment       272..306
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           71 a           91 c           83 g           64 t
ORIGIN      
        1 acatgggagc caccctgtct ttgtctccag gggaaagagc caccctctcc tgcagggcca
       61 gtcagagtgt tggcaacacc ttaacctggt accagcacaa acctgggcag gctcccaagc
      121 tcctcctcta tggtgcatcc accagggcct ccggcatccc aggcaggttc agtgccagtg
      181 ggtctggaac agagtttact ctcaccatca gcagcctgga gcctgaagat gttggaattt
      241 attactgtca gcaggatttt gactggcctc cgacgttcgg ccaagggacc aaggtggaaa
      301 tcaaacgag
//
LOCUS       KCVT01005183             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13839:19431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005183
VERSION     KCVT01005183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13839:19431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82708.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          127 c          110 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccggt gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca ccacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005184             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17315:10523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005184
VERSION     KCVT01005184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17315:10523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82709.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccga agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005185             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20172:21917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005185
VERSION     KCVT01005185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20172:21917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82710.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacctgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005186             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23138:7767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005186
VERSION     KCVT01005186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23138:7767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82711.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005187             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11915:15884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005187
VERSION     KCVT01005187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11915:15884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82712.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          123 c          115 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005188             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13192:4204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005188
VERSION     KCVT01005188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13192:4204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82713.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          118 c          104 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gcccctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005189             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6679:5808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005189
VERSION     KCVT01005189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6679:5808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82714.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttcttacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01005190             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10520:8653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005190
VERSION     KCVT01005190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10520:8653"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82715.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caatggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg ttcctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005191             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4373:16024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005191
VERSION     KCVT01005191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4373:16024"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82716.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaactagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005192             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:22015:14204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005192
VERSION     KCVT01005192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22015:14204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82717.1"
                     /translation="CQQHDNSPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          113 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 gagtattaac gactggttgg cctggtatca acagagacca gggaaggccc ctaagctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgataatt ccccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005193             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9611:11190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005193
VERSION     KCVT01005193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9611:11190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82718.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          118 c          124 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atctagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 gcagtctcca caactcttga tttatgaggt ttccgaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctggacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaagtcaaac gag
//
LOCUS       KCVT01005194             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10514:12349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005194
VERSION     KCVT01005194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10514:12349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82719.1"
                     /translation="CQQYDSDSLSF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          114 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tggagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcagtt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005195             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12363:9685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005195
VERSION     KCVT01005195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12363:9685"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82720.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          112 c          102 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acgttaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005196             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22255:8724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005196
VERSION     KCVT01005196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22255:8724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82721.1"
                     /translation="CMQARDFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          125 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccattgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttcg atagtgagga aggaaacacc tatttggagt ggtacctgca gaggccaggc
      241 cagtctccac aggtcttgat ttatggggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgagaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagactttc cattcacttt cggccccggg
      421 accaaactgg acatcaaacg ag
//
LOCUS       KCVT01005197             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11623:6503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005197
VERSION     KCVT01005197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11623:6503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82722.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          125 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcgcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgacaat cagcagagtg gaggctgagg
      361 atgttggggt gtattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaagcga g
//
LOCUS       KCVT01005198             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7767:16423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005198
VERSION     KCVT01005198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7767:16423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82723.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc tctgcccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgaa gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005199             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7976:6021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005199
VERSION     KCVT01005199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7976:6021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82724.1"
                     /translation="CQQHDNFPYIF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          116 c          105 g           93 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 acatattagc gactggttgg cctggtatca acagaaacca gggaaagccc ctaagctcct
      241 gatctatcgg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag ctttcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgataatt tcccgtacat ttttgaccag gggaccaaac tggagatcaa
      421 acgag
//
LOCUS       KCVT01005200             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23201:18074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005200
VERSION     KCVT01005200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23201:18074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..358
                     /note="immunoglobulin light chain variable region"
     V_region        45..358
     V_segment       45..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <298..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82725.1"
                     /translation="CMQAREFPLTF"
     J_segment       322..358
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>361
                     /gene="IGKC"
BASE COUNT           82 a           91 c          102 g           86 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccgtcact
       61 cttggagagc cggcctccat ctcctgcatg tctagtcaga gcctcttgga tagtgaggat
      121 ggaaacacct atgtggaatg gtacctgcag aagccaggcc agtctccaca gctcttgatt
      181 tatgaggttt cctaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac
      241 actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc
      301 atgcaagctc gagagtttcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      361 g
//
LOCUS       KCVT01005201             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25015:5610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005201
VERSION     KCVT01005201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25015:5610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82726.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          120 c          110 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggttgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01005202             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22294:7943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005202
VERSION     KCVT01005202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22294:7943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82727.1"
                     /translation="CLQGYNTPYNF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          112 c          111 g           95 t
ORIGIN      
        1 atgggggagt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagttga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acctgccggg caagtcagga
      181 cattagcgat tatttaagtt ggtatcagca gaaaccagga aaagctccta agcgcctgat
      241 ctatgctgtg tccagtttgg aaggtggggt cccatcaaga ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gatcttgcga cttattactg
      361 tctacagggt tataataccc cgtacaattt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005203             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:25619:13531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005203
VERSION     KCVT01005203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:25619:13531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82728.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaagccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005204             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9042:19355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005204
VERSION     KCVT01005204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9042:19355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82729.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          122 c          121 g          102 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ctggagagcc ggcctccgtc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tctggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgacttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgta tgcaagcact ggagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005205             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19143:10488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005205
VERSION     KCVT01005205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19143:10488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82730.1"
                     /translation="CQHSYVTPYTF"
     J_segment       385..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          105 a          121 c          103 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agcgtcacca tcacttgcag ggcaagtgcg
      181 aacgttaaca actatttaca ttggtatcag cagagaccag ggaaagcccc tgagctcctg
      241 atccatgctg catccacttt gcaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 ggaacagatt tcactctcac catcaacaac ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcata gttatgtaac cccctacact tttggccagg ggaccaaagt ggagatcaca
      421 cgag
//
LOCUS       KCVT01005206             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21276:8589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005206
VERSION     KCVT01005206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21276:8589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82731.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          114 g          113 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcatag
      181 cctcttggat agtgaggatg gatatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005207             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24390:19959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005207
VERSION     KCVT01005207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24390:19959"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..327
                     /note="immunoglobulin light chain variable region"
     V_region        8..327
     V_segment       8..289
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <267..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82732.1"
                     /translation="CQQYNSLPLTF"
     J_segment       290..327
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>330
                     /gene="IGKC"
BASE COUNT           90 a           79 c           80 g           81 t
ORIGIN      
        1 acatgggcat tcagatgacc cagtctccat cctccctgtc tgcatctctg ggggacagag
       61 tcaccatcac ttgccgggca agtcaggaca ttagcagata tttaaattgg tatcagcaga
      121 aaccggggaa agcccctaag ttcctgatct attatgtaaa ccgtttggaa agtggggtcc
      181 catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc
      241 aacctgaaga ttttgcaact tattattgtc aacagtataa tagtttaccg ctcactttcg
      301 gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005208             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14005:15510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005208
VERSION     KCVT01005208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14005:15510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82733.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005209             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12359:5203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005209
VERSION     KCVT01005209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12359:5203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82734.1"
                     /translation="CQQYNNLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          114 c          106 g          100 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctttaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agttttttga attggtatca gcagaaaccg gggaaagccc ctaacctcct
      241 gatctatttt gcaaaccgtt tggagagtgg ggtcccatca aggttcagcg gcagtgggtc
      301 tgggacaaga ttcactctca ccatcagcag cctccaacct gaagattttg caacttatta
      361 ctgtcaacag tataataatt taccgtacac ttttggccag gggaccaaag ttgagatcaa
      421 acgag
//
LOCUS       KCVT01005210             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22046:7913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005210
VERSION     KCVT01005210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22046:7913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82735.1"
                     /translation="CMQALDFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          122 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tgcagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgcg
      361 gatgttgggg tttattactg catgcaagct ctagactttc ccctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005211             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16581:18383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005211
VERSION     KCVT01005211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16581:18383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82736.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          100 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggcag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cgggggacca aggtggagat caaacgag
//
LOCUS       KCVT01005212             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9913:16002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005212
VERSION     KCVT01005212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9913:16002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82737.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctattttga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttttgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01005213             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21062:12919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005213
VERSION     KCVT01005213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21062:12919"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82738.1"
                     /translation="CQQHDDSPRTF"
     J_segment       391..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          112 a          118 c          112 g           87 t
ORIGIN      
        1 acatgggggg caggagtcag tctcagacag gacacagcat ggacacgagg gtccccgctc
       61 agctcctggg gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc
      121 agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca
      181 gtcaggatat taacacctgg ttggcctggt atcaacagaa gccagggaaa gcccctaagg
      241 tcctgatcta taggacatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg
      301 gatctgggac agatttcact ctcaccatca acagcctgca gcctgaagat atcgcaacat
      361 attactgtca acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01005214             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8565:11354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005214
VERSION     KCVT01005214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8565:11354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82739.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacgggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01005215             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17459:11088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005215
VERSION     KCVT01005215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17459:11088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82740.1"
                     /translation="CQQYNSDPRTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          117 c          108 g           90 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaac ccccgaagcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataaca gtgacccgcg cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01005216             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21940:15418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005216
VERSION     KCVT01005216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21940:15418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..427
                     /note="immunoglobulin light chain variable region"
     V_region        96..427
     V_segment       96..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82741.1"
                     /translation="CGQGTYLLTF"
     J_segment       392..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           92 a          119 c          121 g           98 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cgagtccagt gggggtgttg ttatgactca gtttccgctc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtgcacacca atggatacac atacttgagt tggtatcacc agaggccagg ccaacctcca
      241 aggcgcctca tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacatacctt ctcactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01005217             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12509:18814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005217
VERSION     KCVT01005217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12509:18814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82742.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgt agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005218             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12255:10368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005218
VERSION     KCVT01005218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12255:10368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82743.1"
                     /translation="CMQGIEYPYSF"
     J_segment       405..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          124 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tcttgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggcaacacct atttggagtg gtaccagcag aagccaggcc
      241 agcctccaca gcccttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaaggta tagagtatcc gtatagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01005219             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:7603:15767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005219
VERSION     KCVT01005219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7603:15767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82744.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatgtatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01005220             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17271:15357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005220
VERSION     KCVT01005220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17271:15357"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82745.1"
                     /translation="CQQYDGDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          116 c          112 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgttggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacggtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005221             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19704:8158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005221
VERSION     KCVT01005221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19704:8158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82746.1"
                     /translation="CQQYESDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          114 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgaaagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005222             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19927:12328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005222
VERSION     KCVT01005222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19927:12328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82747.1"
                     /translation="CLQGDTSPFSF"
     J_segment       390..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          114 c          113 g           97 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagccag
      181 gacattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atctatgctg catccagttt ggagagtggg gtcccatcta ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg aggattttgc aacttattac
      361 tgtctacagg gtgatacttc cccgtttagt ttcggcggag ggacccaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005223             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:15726:20681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005223
VERSION     KCVT01005223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15726:20681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82748.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          118 c          111 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tccgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gagaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cctattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005224             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:3868:14244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005224
VERSION     KCVT01005224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3868:14244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..424
                     /note="immunoglobulin light chain variable region"
     V_region        85..424
     V_segment       85..386
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82749.1"
                     /translation="CMQGLEFPITF"
     J_segment       389..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           93 a          117 c          116 g          101 t
ORIGIN      
        1 acatggggag gtcaccttct cacaatgagg ctccctgctc agctcctggg actgctaatg
       61 ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact ctccctgccc
      121 gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct cttggatact
      181 gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc tccacagctc
      241 ttgatttatg atgtttccaa ccgggcctct ggagtcccag acaggttcag tggcagtggg
      301 tcagacgctg atttcacact gagaatcagc agagtggagg ctgaggatgt tggggtttat
      361 tactgcatgc aaggtctaga gtttccaatc actttcggcc ccgggaccaa actggagatc
      421 aaacgag
//
LOCUS       KCVT01005225             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21674:5137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005225
VERSION     KCVT01005225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21674:5137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82750.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat tcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccgt ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct ttttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtgt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaagtgga aatcaaacga g
//
LOCUS       KCVT01005226             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15458:15713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005226
VERSION     KCVT01005226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15458:15713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82751.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005227             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10474:19816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005227
VERSION     KCVT01005227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10474:19816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82752.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          115 c           98 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt ctccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacattc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01005228             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10213:19762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005228
VERSION     KCVT01005228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10213:19762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..388
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82753.1"
                     /translation="CQQGYSYPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          112 a          106 c          105 g          111 t
ORIGIN      
        1 acatggggag tgtgcactgt actgtctgac tcttgaggta aatcctctga taacatgatt
       61 aactgtaaga atatttgttt ttttgtttcc aacctcaggt gccagatgtg acatccagat
      121 gacgcagtct ccatcctccc tgtccgcatc tgtgggagac acagtcacga tcacttgcca
      181 ggcgagtcaa ggcattggca ataatttaaa ttggtatcag cagaaaccag ggaaagcccc
      241 taaagtcctg atctctaagg catccagttt gcaaagtggg attccctctc ggctcagcgg
      301 cagtggatct ggggcggatt tcactctcac catcagcagc ctgcagcctg aagattttgc
      361 cacttactac tgtcaacagg gttatagtta cccgtggaca ttcggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01005229             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22367:9278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005229
VERSION     KCVT01005229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22367:9278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82754.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgtgga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005230             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:27646:7603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005230
VERSION     KCVT01005230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:27646:7603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82755.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggttcc atcaaggttc agcggcactg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atttctgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005231             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12040:4047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005231
VERSION     KCVT01005231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12040:4047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82756.1"
                     /translation="CQQYNSLPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctcctt ctgtcggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggtcattagg agttatttaa attggtatca gcagaaaccg gggaaagccc ctaaactcct
      241 gatctattat gtaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtgtatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagactttg gaacttatta
      361 ctgtcaacag tataatagtt taccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005232             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10547:3765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005232
VERSION     KCVT01005232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10547:3765"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82757.1"
                     /translation="CQQYFSSPFTF"
     J_segment       386..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           95 a          126 c          112 g           93 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaagttata ttgactcagt
      121 ctccagccac gctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg tagcagctta gcctggtacc agcggaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtgtatt
      361 actgtcagca gtattttagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 gacgag
//
LOCUS       KCVT01005233             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13217:3828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005233
VERSION     KCVT01005233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13217:3828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..372
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82758.1"
                     /translation="CQQYYSFPITF"
     J_segment       386..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          100 a          113 c          113 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gatcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattaaca cctggttaat ttggtatcag cagaaaccag ggaaagcccc taaggccctg
      241 atctataagg catccagttt gcaaggtggg gtcccttcca ggttcagcgg cagtggatct
      301 ggggcagact tcactctcac catcaccaac ctgcagcctg aagattttgg aatttattac
      361 tgtcaacaat attatagttt tccgatcact ttcggtgggg ggaccaaggt ggagatcagg
      421 cgag
//
LOCUS       KCVT01005234             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:8759:17860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005234
VERSION     KCVT01005234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8759:17860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..405
                     /note="immunoglobulin light chain variable region"
     V_region        103..405
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82759.1"
                     /translation="CQKYSSSPFTF"
     J_segment       387..405
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           88 a          120 c          107 g           90 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat tttgactcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc ccccagactc
      241 ctcgtctatg gtgcatccag gagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt tgcagtgtat
      361 tactgtcaga agtatagtag ttccccattc actttcggcc ccggg
//
LOCUS       KCVT01005235             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10837:7331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005235
VERSION     KCVT01005235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10837:7331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82760.1"
                     /translation="CLQYRSFPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          105 g           98 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtgggaga cactgtcacc atcacttgcc ggacaagtca
      181 aggtatcagc aattatttac attggtttca gcagaaacca gggaaagccc ctaagctcct
      241 gatctatgct gcatccagtc tggcaagtgg ggtcccatca aggttcagcg gcagtgcatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttattc
      361 ctgtctacag tatagaagtt tcccgtacag ttttggccag gggaccaaac tggagatcaa
      421 acgag
//
LOCUS       KCVT01005236             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:24420:8557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005236
VERSION     KCVT01005236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24420:8557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82761.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca caaaccaggc
      241 cagtctccag agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggc tttattactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg aggtcaaacg ag
//
LOCUS       KCVT01005237             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11637:5635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005237
VERSION     KCVT01005237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11637:5635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82762.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          111 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggaacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005238             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19616:11091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005238
VERSION     KCVT01005238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19616:11091"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82763.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           92 a          120 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccgca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcgcaggga
      421 ccaaggtgga gatcagacga g
//
LOCUS       KCVT01005239             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21150:5303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005239
VERSION     KCVT01005239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21150:5303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    37..358
                     /note="immunoglobulin light chain variable region"
     V_region        37..358
     V_segment       37..321
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82764.1"
                     /translation="CQQNSNWPLTF"
     J_segment       322..358
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>361
                     /gene="IGKC"
BASE COUNT           86 a          101 c          101 g           73 t
ORIGIN      
        1 acatgggggc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
       61 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      121 gtcagcagca gcgtagcctg gtaccagcag aaacctgggc aggctcccag actcctcatg
      181 tatggtgcat ccaacagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      241 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      301 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      361 g
//
LOCUS       KCVT01005240             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19215:4459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005240
VERSION     KCVT01005240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19215:4459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82765.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          118 c          106 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtctcc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005241             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13861:6669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005241
VERSION     KCVT01005241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13861:6669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82766.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgaag atggaaatac ctatttggaa tggcaccggc agatgccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cactctgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctgacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005242             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12742:10373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005242
VERSION     KCVT01005242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12742:10373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82767.1"
                     /translation="CQQYNSDPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          113 c          108 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcgagtc
      181 agggcattag aagttattta gcgtggtatc agcagaaacc aggaaaagcc ccgaaggcct
      241 tgatctatta cgcatccatt ttagaaagtg cggtaccatc aaggttcagc ggcagtggat
      301 ctgggacaga gttcactctc accatcagca gccttcagtc tgacgatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01005243             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16472:20865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005243
VERSION     KCVT01005243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16472:20865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82768.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           96 a          126 c          113 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaaactcc
      241 ttgtccatag tgcattcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005244             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14866:11932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005244
VERSION     KCVT01005244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14866:11932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82769.1"
                     /translation="CMQYIHMPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaagctcc ctgctcagct
       61 cctggggctg ctaatgctct ggctctctgg gtccagtggg gatattgtga tgacccagac
      121 tccactctcc ctgtccgtca cccctggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgaag atggaaacac ctatttggat tggtacctgc agaagccggg
      241 ccagtctcca cagcccttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      301 gttcaatggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctgg
      361 ggatgttggg gtttattact gcatgcaata tatacacatg cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005245             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:23330:16252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005245
VERSION     KCVT01005245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23330:16252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82770.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg acatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005246             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13777:8653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005246
VERSION     KCVT01005246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13777:8653"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82771.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          117 c          122 g          107 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcactct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaagatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01005247             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15059:5386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005247
VERSION     KCVT01005247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15059:5386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82772.1"
                     /translation="CQQNSNWPLTF"
     J_segment       379..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           99 a          121 c          114 g           84 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ccccagcaca gcttctcttc
       61 ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca gtctccagcc
      121 accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag tcagagtgtc
      181 agcagcagcg tagcctggta ccagcagaaa cctgggcagg ctcccagact cctcatgtat
      241 ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg gtctgggaca
      301 gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta ttattgtcag
      361 cagaatagta actggcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01005248             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12051:11558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005248
VERSION     KCVT01005248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12051:11558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82773.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005249             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11240:11600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005249
VERSION     KCVT01005249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11240:11600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82774.1"
                     /translation="CQQGDSYPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          112 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 cttcctccct gtctgcatct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagaga ttatttaaat tggtatcagc agcaaccggg gaaagcccct aaactcctga
      241 tgtattatgc aaacagtctg gcaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg tgacagttat cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005250             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18904:15188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005250
VERSION     KCVT01005250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18904:15188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82775.1"
                     /translation="CMQALEFPLTF"
     J_segment       409..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           98 a          120 c          123 g          105 t
ORIGIN      
        1 acatgggggg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gtaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa tacctatttg gaatggcacc ggcagatgcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagag tttcctctga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01005251             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:24331:15367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005251
VERSION     KCVT01005251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:24331:15367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82776.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          110 c          108 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattgaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcgttaac gtttatttaa attggtatca acagaaaccg gggaaagccc ctaagcccct
      241 gatcttttat gcaaaccgtt tggaacgtgg ggtcccatca aggttcagcg gcagtggatc
      301 tcaacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aagttattat
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005252             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11331:20663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005252
VERSION     KCVT01005252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11331:20663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82777.1"
                     /translation="CLQGDTSPFSF"
     J_segment       388..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          114 c          112 g           97 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagccagga
      181 cattaacgat tatttaagtt ggtatcagca gaaaccagga aaacctccta agcgcctgat
      241 ctatgctgca tccagtttgg agagtggggt cccatctagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagtctgag gattttgcaa cttattactg
      361 tctacagggt gatacttccc cgtttagttt cggcggaggg acccaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005253             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12523:15559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005253
VERSION     KCVT01005253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12523:15559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82778.1"
                     /translation="CQQHDNMPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          115 c          115 g           87 t
ORIGIN      
        1 acatggggga gtcagtcgca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac agagtcacca tcacttgcag agccagtcag
      181 ggtattagca actggttggc ctggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctataggg catggaatct ggaaacaggg gtcccatcaa ggttcagtgg aagtggatcc
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgataatat gccgctcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01005254             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10335:11207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005254
VERSION     KCVT01005254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10335:11207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82779.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          117 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctctctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagccta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005255             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8118:13374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005255
VERSION     KCVT01005255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8118:13374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82780.1"
                     /translation="CLQFKTYPNSF"
     J_segment       380..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           99 a          115 c          104 g          100 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatttctt gccgggcaag tcagggtatt
      181 agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctaagct cctcatctat
      241 gctgcatcca gtttggccgg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcac cagcctgcag cctgaagatt ttgcaactta ttactgtctg
      361 cagtttaaaa cttacccgaa cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01005256             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14121:16222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005256
VERSION     KCVT01005256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14121:16222"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82781.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctactgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005257             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19097:6573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005257
VERSION     KCVT01005257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19097:6573"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82782.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01005258             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13033:21932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005258
VERSION     KCVT01005258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13033:21932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82783.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccttggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005259             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:11183:10084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005259
VERSION     KCVT01005259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11183:10084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82784.1"
                     /translation="CMQYIHMPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctgggt ccagtgggga tattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggattg gtacctgcag aagccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaagcgggc ccctggagtc ccagacaggt
      301 tcaatggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttgggat ttattactgc atgcaataca tacacatgcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005260             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10030:16120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005260
VERSION     KCVT01005260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10030:16120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82785.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          108 c          110 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtttc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005261             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:23359:6301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005261
VERSION     KCVT01005261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23359:6301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82786.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt ttctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005262             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19498:24290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005262
VERSION     KCVT01005262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19498:24290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82787.1"
                     /translation="CLQGDTAPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gcaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattaacga ttatttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca gcttattact
      361 gtctacaggg tgatactgcc ccgttcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005263             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14191:10840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005263
VERSION     KCVT01005263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14191:10840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82788.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgtatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005264             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15749:21670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005264
VERSION     KCVT01005264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15749:21670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82789.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          124 c          122 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccaggca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01005265             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:4332:11254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005265
VERSION     KCVT01005265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4332:11254"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82790.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          119 c          118 g          109 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaatac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccacagtg gagattaaac gag
//
LOCUS       KCVT01005266             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9930:17020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005266
VERSION     KCVT01005266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9930:17020"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82791.1"
                     /translation="CQQHNTYPLTF"
     J_segment       394..427
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          109 a          118 c          107 g           96 t
ORIGIN      
        1 acatggggaa cgcagagtac atgggactca ggacacagca tggacatgag ggtccccgtt
       61 cagctcctgg ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca
      181 agtcaggaca ttagtaatga tttagcctgg tatcagcaga aaccagggaa agccccgaag
      241 cccctgatgt attacgcatc caatttggaa agtggggtcc cctcaaggtt cagtggcagt
      301 ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaagt
      361 tattactgtc aacagcataa tacttatcca ttgactttcg gccccgggac caaactggac
      421 atcaaacgag
//
LOCUS       KCVT01005267             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16436:17349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005267
VERSION     KCVT01005267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16436:17349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82792.1"
                     /translation="CQQYNSLPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          109 c          110 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattag ttattattta aattggtatc aacagaaacc ggggaaagcc cctaaggtcc
      241 tgatctatta cacaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaggatttt gcaagttatt
      361 actgtcaaca atataatagt ttaccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005268             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22731:17588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005268
VERSION     KCVT01005268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22731:17588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82793.1"
                     /translation="CMQGLEFPPTF"
     J_segment       407..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          125 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg cgacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggt gatggaaaca cctatttgga atggttcctc cagaggccag
      241 gccagtctcc acacctcttg atttatgggg cttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag gtctagagtt tcctccgacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005269             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13251:4734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005269
VERSION     KCVT01005269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13251:4734"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..386
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82794.1"
                     /translation="CQQRNSYPYIYSF"
     J_segment       394..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          104 a          115 c          114 g          100 t
ORIGIN      
        1 acatggggca ggagttagac ccagtctgga cgcagcatgg acatcagggt cctcgctcag
       61 cttctcgggc tcctgctgct ctggctccca ggtgccagat gtgacattca gttgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcaagt
      181 cagggcatta gcagttattt agcctggtat cagcagaaac cagggaaagc ccctaagctc
      241 ctgatctata aggcgtccag tttgcagagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ccgaagattt tgcagtttat
      361 tactgtcaac agcgtaatag ttacccgtac atatacagtt ttggccaggg gaccaaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01005270             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22045:18957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005270
VERSION     KCVT01005270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22045:18957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82795.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cccaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01005271             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:27658:11824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005271
VERSION     KCVT01005271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:27658:11824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..329
                     /note="immunoglobulin light chain variable region"
     V_region        6..329
     V_segment       6..291
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82796.1"
                     /translation="CMQALDFPLTF"
     J_segment       293..329
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>332
                     /gene="IGKC"
BASE COUNT           75 a           87 c           93 g           77 t
ORIGIN      
        1 atgggagact ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag
       61 gtctagtcag agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca
      121 gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt
      181 cccagacagg ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt
      241 ggaggctgcg gatgttgggg tttattactg catgcaagct ctagactttc ccctcacttt
      301 cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005272             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10738:7727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005272
VERSION     KCVT01005272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10738:7727"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..368
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82797.1"
                     /translation="CQQGYYTPFTF"
     J_segment       383..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT           97 a          121 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg cccgatgtga catccagatg acccagtctc
      121 catcgtccct gtctgcatct gtaggagaca aagtcaccat ctcttgccga accagtcagg
      181 gtattagcag ctggttagcc tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctataaggc gtccagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgct acttattatt
      361 gtcaacaggg ttactatacc ccattcactt tcggccccgg gaccaaactg gatatcaatc
      421 gag
//
LOCUS       KCVT01005273             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:3330:9599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005273
VERSION     KCVT01005273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3330:9599"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82798.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          116 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacgtgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005274             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20822:10001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005274
VERSION     KCVT01005274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20822:10001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82799.1"
                     /translation="CMQSLELPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          127 c          113 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caatggggac attctgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcgtggat agtgaggatg ggaacaccta tttggaatgg ttcctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgacgtttc cacccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaatctct agagcttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01005275             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13923:9714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005275
VERSION     KCVT01005275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13923:9714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..387
                     /note="immunoglobulin light chain variable region"
     V_region        66..387
     V_segment       66..349
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82800.1"
                     /translation="CQQYNSLPYSF"
     J_segment       350..387
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>390
                     /gene="IGKC"
BASE COUNT           94 a          100 c          101 g           95 t
ORIGIN      
        1 acatggggag ggtccccgct cagctcctgg ggctcctgct gctctggctc ccaggtgcca
       61 gatgtgacat tgagatgacc cagtctccat cctccctgtc tgcttctgta ggagacagag
      121 tcaccatcac ttgccgggca agtcagggcg ttaacgttta tttaaattgg tatcagcaga
      181 aaccggggaa agcccctaag cccctgatct tttatgcaaa ccgtttggaa cgtggggtcc
      241 catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc
      301 aacctgaaga ttttgcaagt tattattgtc aacagtataa tagtttaccg tacagttttg
      361 gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01005276             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10723:9463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005276
VERSION     KCVT01005276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10723:9463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82801.1"
                     /translation="CMEALEFPYSF"
     J_segment       405..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacatcgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatgttgag gatggaaaca cctatttgga atggcacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatggaag ctctagaatt tccctacagt tttggccagg
      421 ggaccaaact ggagatcaag cgag
//
LOCUS       KCVT01005277             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12903:5266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005277
VERSION     KCVT01005277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12903:5266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82802.1"
                     /translation="CLQYKSYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          107 a          114 c          103 g           99 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 atattagcac ttatttaaat tggtttcagc agaaaccagg gaaagcccct agactcctga
      241 tctatgctgc atccagtttg gaaagtgggg tcccctcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga agattttgca acttatcact
      361 gtctacagta taaaagttac cctctcactt tcggcggagg gaccaaggtg gagatcaaaa
      421 gag
//
LOCUS       KCVT01005278             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:5043:6480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005278
VERSION     KCVT01005278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:5043:6480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82803.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgagtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005279             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10678:15109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005279
VERSION     KCVT01005279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10678:15109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..428
                     /note="immunoglobulin light chain variable region"
     V_region        92..428
     V_segment       92..390
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82804.1"
                     /translation="CMQGTHLPFTF"
     J_segment       391..428
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          119 c          110 g          103 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg ggatgttgtg atgactcagt ctccactctc
      121 cctgtctatc actcttggac aaccggcctc catttcctgc aggtctagtc acacccttgt
      181 acacagtgat gggaaaacct acttgaattg gtatcagcag aagccaggcc aacctccaag
      241 gcgcctaatt tatcaggttt ctaaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gaggctgagg atgttggagt
      361 ttattactgc atgcaaggta cacaccttcc attcactttc ggccccggga ccaaactgga
      421 tatcaaacga g
//
LOCUS       KCVT01005280             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16319:18918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005280
VERSION     KCVT01005280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16319:18918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82805.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctaa agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005281             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12758:21145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005281
VERSION     KCVT01005281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12758:21145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..246
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82806.1"
                     /translation="CQKYSSFPFTF"
     J_segment       247..284
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           68 a           79 c           80 g           60 t
ORIGIN      
        1 acatgggggg gaaagagcca ccctctcctg cagggccagt cagagtgttg gcagcagctt
       61 agcctggtac cagcagaaaa ttgggcgggc ccccaggctc ctcatctatg gtgcatccaa
      121 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag acttcactct
      181 caccatcagc agcctggagc ctgaagattt tgcagtgtat tactgtcaga agtatagtag
      241 tttcccattc actttcggcc ccgggaccaa actggatatc aaacgag
//
LOCUS       KCVT01005282             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:27170:14172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005282
VERSION     KCVT01005282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:27170:14172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82807.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcggagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005283             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17794:14810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005283
VERSION     KCVT01005283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17794:14810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82808.1"
                     /translation="CLQTKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcagca gaaaccagga caacctccta
      241 aactcctggt ttatcaagca accaataggg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gcccgatttc accctcacaa ttaatcctgt ggaacctgac gatgctgcta
      361 attattactg tctgcagact aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01005284             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17657:14088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005284
VERSION     KCVT01005284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17657:14088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82809.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          123 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ttccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag gctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005285             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6967:4494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005285
VERSION     KCVT01005285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6967:4494"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82810.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005286             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10647:15437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005286
VERSION     KCVT01005286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10647:15437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82811.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggt agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01005287             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:24196:8873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005287
VERSION     KCVT01005287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24196:8873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82812.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag caaaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcacc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005288             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:19886:15761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005288
VERSION     KCVT01005288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19886:15761"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82813.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagtcac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005289             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:3538:14104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005289
VERSION     KCVT01005289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3538:14104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..372
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82814.1"
                     /translation="CQQYYSFPITF"
     J_segment       386..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          100 a          114 c          113 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gatcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattaaca cctggttaat ttggtatcag cagaaaccag ggaaagcccc taaggccctg
      241 atctataagg catccagttt gcaaggtggg gtcccttcca ggttcagcgg cagcggatct
      301 ggggcagact tcactctcac catcaccaac ctgcagcctg aagattttgg aatttattac
      361 tgtcaacaat attatagttt tccgatcact ttcggtgggg ggaccaaggt ggagatcagg
      421 cgag
//
LOCUS       KCVT01005290             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:14620:3146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005290
VERSION     KCVT01005290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14620:3146"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82815.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          117 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgat
//
LOCUS       KCVT01005291             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:7393:2296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005291
VERSION     KCVT01005291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7393:2296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82816.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ccctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005292             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16203:14310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005292
VERSION     KCVT01005292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16203:14310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82817.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          120 c          110 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcatttc caatgattta gcctggtatc agcagagacc agggaaagcc ccgaagcccc
      241 tgatctttta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005293             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15010:17471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005293
VERSION     KCVT01005293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15010:17471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82818.1"
                     /translation="CQQHDNSPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          110 a          117 c          114 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcagagtatt aacgactggt tggcctggta tcaacagaga ccagggaagg cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgata attccccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01005294             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13587:6168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005294
VERSION     KCVT01005294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13587:6168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82819.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          118 c          109 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagtca
      181 ggatattaat acctggttgg cctggtatca acagaaacca ggaaaagccc ctaaactcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcggtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005295             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23409:6290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005295
VERSION     KCVT01005295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23409:6290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..402
                     /note="immunoglobulin light chain variable region"
     V_region        82..402
     V_segment       82..365
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82820.1"
                     /translation="CQQYNTLPLTF"
     J_segment       369..402
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>406
                     /gene="IGKC"
BASE COUNT          103 a          104 c          104 g           95 t
ORIGIN      
        1 acatggggac acagcatgga catgagggtc cccgctcagc tcctggggct cctgctgctc
       61 tggctcccag gtgccagatg tgacattcag atgacccagt ctccatcctc cctgtctgca
      121 tctgtaggag acagagtcac catcacttgc cgggcaagtc agggcattag tagttattta
      181 aattggtatc agcagaaacc ggggaaagcc cctaaggtcc tcatctatta tacaaaccgt
      241 ttggaaagtg gggtcccatc aaggttcagt ggcagtggat ctgggacaga gttcactctc
      301 accatcagca gcctgcaacc tgaggatttt gcaacttatt actgtcaaca gtataatact
      361 ttaccgttga cgttcggcca agggaccaag gtggaaatca aaggag
//
LOCUS       KCVT01005296             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16912:11478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005296
VERSION     KCVT01005296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16912:11478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..390
                     /note="immunoglobulin light chain variable region"
     V_region        57..390
     V_segment       57..352
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <330..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82821.1"
                     /translation="CLQSKNSPWSF"
     J_segment       353..390
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>393
                     /gene="IGKC"
BASE COUNT           92 a          106 c          105 g           90 t
ORIGIN      
        1 acatgggggc tcctttcctg tggatcctcc tgctctgtgc tccaggctgc agtggggaca
       61 ttgtgctgac ccagtctcca gcctctttgg ccgtgtctcc agggcagagg gccaccatca
      121 cctgcagagc cagtgagagt gtcagtgcct ttggaataag cctcattcac tggtatcaac
      181 agaaaccagg acaacctcct aaactcctga tttaccaagc aatcaataag gagactgggg
      241 tcccagccag gttcagcggc agtgggtctg ggaccgattt caccctcaca attaatcctg
      301 tggaacctga cgatggtgca gattattact gtctgcagag taagaattct ccgtggtcgt
      361 tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005297             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13713:13789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005297
VERSION     KCVT01005297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13713:13789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82822.1"
                     /translation="CMQALDFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           94 a          121 c          121 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatgc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgcggat
      361 gttggggttt attactgcat gcaagctcta gactttcccc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01005298             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:6893:4385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005298
VERSION     KCVT01005298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6893:4385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82823.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctactgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005299             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21538:12754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005299
VERSION     KCVT01005299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21538:12754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82824.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccaggcac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctattg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005300             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:4879:12398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005300
VERSION     KCVT01005300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4879:12398"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82825.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca caccgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005301             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15858:12510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005301
VERSION     KCVT01005301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15858:12510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82826.1"
                     /translation="CQHSFDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          117 c          108 g           96 t
ORIGIN      
        1 atgggggagt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagtccctg agctcctgat
      241 ctatgctgca tcgtctttgc aaagtggggt cccatcaagg ttcagcggca gtgggtctgg
      301 gacagatttc accctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcacagt tttgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005302             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:11082:14637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005302
VERSION     KCVT01005302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11082:14637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82827.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01005303             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9496:12179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005303
VERSION     KCVT01005303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9496:12179"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82828.1"
                     /translation="CQQYNRLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          109 a          111 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatagatta cctcggacgt tcggccaagg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01005304             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19603:15588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005304
VERSION     KCVT01005304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19603:15588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..400
                     /note="immunoglobulin light chain variable region"
     V_region        113..400
     V_segment       113..363
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82829.1"
                     /translation="CQQDFGWPPTF"
     J_segment       366..400
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>403
                     /gene="IGKC"
BASE COUNT           95 a          110 c          112 g           86 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagactgttg gcagactcac aaactcctca tttatggtgc atccagcagg
      241 gccaccggca tcccagacag gttcagtggc agtgggtctg gaacagagtt cactctcacc
      301 atcagtagtc cggagcctga ggatgttgga gtttattact gtcagcagga ttttggctgg
      361 cctccgacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005305             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8894:3800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005305
VERSION     KCVT01005305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8894:3800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82830.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          125 c          110 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcaa cagcttagcc tggtaccaac aaaaacctgg gcagcctccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagaggc agtgggtctg
      301 ggacagactt cactctcacc atcaccagcc tggagcctga agatgttgca gtttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005306             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13873:16914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005306
VERSION     KCVT01005306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13873:16914"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82831.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005307             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6172:15483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005307
VERSION     KCVT01005307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6172:15483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82832.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagaac cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005308             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6684:2986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005308
VERSION     KCVT01005308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6684:2986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82833.1"
                     /translation="CQQYKSLPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          115 c          105 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaccagt tttttaaatt ggtatcagca gaaaccgggg aaggccccta agctcctgat
      241 ctattttgaa aatcgtctgg aaagtggggt cccgtcaagg ttcggcggca gtggatcagg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aaaagtttac cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01005309             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:9519:14093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005309
VERSION     KCVT01005309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9519:14093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82834.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005310             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18365:17376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005310
VERSION     KCVT01005310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18365:17376"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82835.1"
                     /translation="CMQALEFPYTF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagagt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 accctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctcctc aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcaacagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttacacttt tggccagggg
      421 accacagtgg agatcaaacg ag
//
LOCUS       KCVT01005311             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15744:14980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005311
VERSION     KCVT01005311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15744:14980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82836.1"
                     /translation="CQQYHSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tagcagttat ttagcgtggt atcggcagaa gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctaca gcctgaagat tttgcaactt attactgtca
      361 acagtatcac agtgactcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005312             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14077:13666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005312
VERSION     KCVT01005312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14077:13666"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82837.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          118 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005313             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16200:20583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005313
VERSION     KCVT01005313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16200:20583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82838.1"
                     /translation="CQQYTSFPLTF"
     J_segment       385..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          102 a          122 c          107 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 acgttagcag tcatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattttgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acctatcact
      361 gtcaacagta cactagtttc cccctcactt tcggccccgg gaccaaactg gatatcaagc
      421 gag
//
LOCUS       KCVT01005314             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21465:2284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005314
VERSION     KCVT01005314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21465:2284"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82839.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa actagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005315             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19846:4381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005315
VERSION     KCVT01005315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19846:4381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82840.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          123 c          115 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagtca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005316             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10681:4086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005316
VERSION     KCVT01005316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10681:4086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82841.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           93 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag tctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag ccttcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005317             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20612:11472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005317
VERSION     KCVT01005317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20612:11472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82842.1"
                     /translation="CQHSFRTPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          118 c          111 g           97 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg cctctgctca
       61 gctcctaggg ctcctgctgc tctggctccc aggcgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accgtcactt gcagggctag
      181 tgagagcgtt agcaccaaat tacattggta tcaacagaaa ccagggaaag cccctaagct
      241 cctgatcttt gctgcgtcca ctttgcaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctggaaca gatttcactc tcaccatcag cagcctgcag cctgaagatg ttgcaacttt
      361 ttactgtcag catagttttc gtaccccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01005318             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20878:9293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005318
VERSION     KCVT01005318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20878:9293"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82843.1"
                     /translation="CQQVYGNPIFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          113 c          104 g          104 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagtaat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcg aaattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcagctt attactgtca
      361 acaggtttat ggtaatccta tattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01005319             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20055:19220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005319
VERSION     KCVT01005319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20055:19220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82844.1"
                     /translation="CMQALEFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          100 t
ORIGIN      
        1 acatgggcac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatggt gaggatggaa acacctattt ggagtggcac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatct
      361 tggggtttat tactgcatgc aagctctaga gtttccgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01005320             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15962:18673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005320
VERSION     KCVT01005320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15962:18673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82845.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 cgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005321             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20818:15726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005321
VERSION     KCVT01005321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20818:15726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82846.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tttcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005322             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18837:11816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005322
VERSION     KCVT01005322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18837:11816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    53..392
                     /note="immunoglobulin light chain variable region"
     V_region        53..392
     V_segment       53..355
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82847.1"
                     /translation="CMQALEFPLTF"
     J_segment       356..392
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>395
                     /gene="IGKC"
BASE COUNT           87 a          102 c          112 g           94 t
ORIGIN      
        1 acatgggcag ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt
       61 gatgacccag actccactct ccctgcccgt cacccttgga gagccggtct ccatctcctg
      121 caggtctagt cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct
      181 gcacaaacca ggccagtctc cagagctctt gatttatgag gtttccaagc gggcctctgg
      241 agtcccagac aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag
      301 agtggaggct gaggatgttg ggctttatta ctgcatgcaa gctctagagt ttcctctcac
      361 tttcggcgga gggaccaagg tggaggtcaa acgag
//
LOCUS       KCVT01005323             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13410:16319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005323
VERSION     KCVT01005323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13410:16319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82848.1"
                     /translation="CLQYNSAPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          113 c          107 g           96 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtcag
      181 gacattagga attctttaaa ttggtttcag cagaaaccag gaaaagctcc taagcgcctg
      241 atctatgatg catccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagtat tcactctcag tatcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataacagtgc ccctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005324             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9010:4612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005324
VERSION     KCVT01005324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9010:4612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..379
                     /note="immunoglobulin light chain variable region"
     V_region        111..379
     V_segment       111..342
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82849.1"
                     /translation="CQQGDSYPRTF"
     J_segment       344..379
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>382
                     /gene="IGKC"
BASE COUNT          100 a           99 c          102 g           81 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtcaccatc
      121 acttgccggg caagtcagga cattagagat tatttaaatt ggtatcagca gcaaccgggg
      181 aaagccccta aactcctgat gtattatgca aacagtctgg caagtggagt cccatcaagg
      241 ttcagcggca gtggatctgg gacagaattc agtctcacca tcagcagcct gcagcctgaa
      301 gattttgcaa cttattactg tcaacagggt gacagttatc ctcggacgtt cggccaaggg
      361 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005325             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16506:18820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005325
VERSION     KCVT01005325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16506:18820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82850.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          125 c          108 g           86 t
ORIGIN      
        1 acatggggaa ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcaac agcttagcct ggtaccaaca aaaacctggg cagcctccca ggctcctcat
      241 ctatggttca tccagcaggg ccactggcat cccagacagg ttcagaggca gtgggtctgg
      301 gacagacttc actctcacca tcaccagcct ggagcctgaa gatgttgcag tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005326             377 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12871:12764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005326
VERSION     KCVT01005326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 377)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12871:12764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..374
                     /note="immunoglobulin light chain variable region"
     V_region        42..374
     V_segment       42..337
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <314..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82851.1"
                     /translation="CMQALEFPLTF"
     J_segment       338..374
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        375..>377
                     /gene="IGKC"
BASE COUNT           88 a          100 c          100 g           89 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaca ctgatgaccc agactccact
       61 ctccctgccc gtcactcttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      121 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaaac caggccagtc
      181 tccacgactc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      241 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      301 tggggtttat tactgcatgc aagctctaga gtttcctctc actttcggtg gagggaccaa
      361 ggtggagatc aaacgag
//
LOCUS       KCVT01005327             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18262:18198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005327
VERSION     KCVT01005327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18262:18198"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82852.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          109 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcacggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcttccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttttttaaa ttggtatcag cagaaaccgg ggaaagcccc taaggccctg
      241 atctattatg caaaccggtt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaatctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt agagatcaaa
      421 cgag
//
LOCUS       KCVT01005328             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23028:15788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005328
VERSION     KCVT01005328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23028:15788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82853.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccatg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01005329             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25383:15093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005329
VERSION     KCVT01005329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25383:15093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82854.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt cgggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005330             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21073:11759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005330
VERSION     KCVT01005330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21073:11759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82855.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttggcg tggtatcacc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01005331             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10748:17375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005331
VERSION     KCVT01005331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10748:17375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82856.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctagagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005332             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14965:13107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005332
VERSION     KCVT01005332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14965:13107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82857.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggc tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005333             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19839:10614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005333
VERSION     KCVT01005333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19839:10614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82858.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005334             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13903:13154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005334
VERSION     KCVT01005334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13903:13154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82859.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          103 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtaccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005335             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6178:11122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005335
VERSION     KCVT01005335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6178:11122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82860.1"
                     /translation="CQQVYTNPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          113 c          103 g          105 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccctg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgaa atccagatga cccagtctcc
      121 atctgccttg tctgcatctg taggagacag agtcaccatc tcttgccggg caagtcagaa
      181 catttatagt tatttagggt ggtatcagca gaaaccaggg aaagccccta agctcctgat
      241 ctatgctgta tccagattgc aaagtggaat tccctctcgg ttcagcggca gtggatccgg
      301 gacagatttc actctcacca ttagcagcct gcagcctgaa gattctgcag tttattactg
      361 tcaacaggtt tatactaatc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01005336             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22273:5794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005336
VERSION     KCVT01005336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22273:5794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82861.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 accctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttt acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005337             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:17052:13073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005337
VERSION     KCVT01005337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17052:13073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82862.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           92 t
ORIGIN      
        1 acagggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tatcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005338             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:2926:13456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005338
VERSION     KCVT01005338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:2926:13456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82863.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagtagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005339             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:14846:2136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005339
VERSION     KCVT01005339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14846:2136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82864.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          119 c          107 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacaa cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005340             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:7702:21559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005340
VERSION     KCVT01005340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7702:21559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82865.1"
                     /translation="CQQGYSYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          115 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtgggagaca cagtcacgat ctcttgccag gcgagtcaag
      181 gcattgacaa taatttaaat tggtttcagc agacaccagg gaaagcccct aaactcctga
      241 tttataaggc atccagtttg gaaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcaccc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005341             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10570:10679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005341
VERSION     KCVT01005341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10570:10679"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82866.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005342             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16540:18359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005342
VERSION     KCVT01005342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16540:18359"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82867.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcat cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005343             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14396:17125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005343
VERSION     KCVT01005343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14396:17125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82868.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005344             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:5287:18460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005344
VERSION     KCVT01005344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5287:18460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82869.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tttcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcggtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005345             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22078:10546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005345
VERSION     KCVT01005345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22078:10546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..382
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82870.1"
                     /translation="CQQRNSYPYMYSF"
     J_segment       388..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          104 a          113 c          111 g          101 t
ORIGIN      
        1 acatggggag ttagacccag tctggacgca gcatggacat cagggtcctc gctcagcttc
       61 tcgggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagttg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcaagtcagg
      181 acattagcag ttctttagcc tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctataaggc gtccagtttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaggctga agattttgca gtttattact
      361 gtcaacagcg taatagttac ccatacatgt acagttttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01005346             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9370:14343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005346
VERSION     KCVT01005346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9370:14343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82871.1"
                     /translation="CLQYKNFPLSF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          111 c          104 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat gggcatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag gtgtgacatc cagatgactc agtctccgtc
      121 ttccctgtct gcatctctag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 taacagttat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tggtgcatcc agtttggaaa gtgaggtccc attaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atttctgtct
      361 acagtataaa aatttcccgc tctctttcgg cggagggacc agggtggaca tcaaacgag
//
LOCUS       KCVT01005347             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22087:14820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005347
VERSION     KCVT01005347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22087:14820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..442
                     /note="immunoglobulin light chain variable region"
     V_region        100..442
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82872.1"
                     /translation="CMQALEFPPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          123 c          117 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagaat
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattattg catgcaagct ctagagtttc ctccattcac tttcggcccc
      421 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01005348             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22175:8884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005348
VERSION     KCVT01005348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22175:8884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..319
                     /note="immunoglobulin light chain variable region"
     V_region        8..319
     V_segment       8..281
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82873.1"
                     /translation="CLQSKNSPWTF"
     J_segment       282..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           87 a           82 c           83 g           70 t
ORIGIN      
        1 acatgggcag cctctttggc cgtgtctcca gggcagaggg ccaccatcgt ctgcagagcc
       61 agtgagagtg tcaatgtctt tggaataaac ctcattcact ggtatcagca gaaaccagga
      121 caacctccta aacccctgat ttaccaagca tccaataaag aaactggggt cccagccagg
      181 ttcagcggca gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaagctgac
      241 gatgctgcag attattactg tctgcagagt aagaattctc cgtggacgtt tggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005349             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:21836:10484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005349
VERSION     KCVT01005349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21836:10484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82874.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgtagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005350             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21158:13777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005350
VERSION     KCVT01005350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21158:13777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82875.1"
                     /translation="CQQYNTLPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          109 c          109 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cagatattta aattggtatc agcagaaacc ggggaaagcc cctaagttcc
      241 tgatctatta tgtaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 attgtcaaca gtataatact ttaccgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005351             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14452:11427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005351
VERSION     KCVT01005351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14452:11427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..442
                     /note="immunoglobulin light chain variable region"
     V_region        121..442
     V_segment       121..405
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82876.1"
                     /translation="CQQDFGWPPTF"
     J_segment       408..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          109 a          122 c          124 g           90 t
ORIGIN      
        1 acatgggaag cacgcagagt acatggggag gaactgctca gttaggaccc agagggaacc
       61 atggaagctc cagcacagct tctcttcctc ctgctactct ggatcccaga tatcaccgga
      121 gaaatagtga tgacgcagtc tccagccatt ctgtctttgt ctccagggga aagagccacc
      181 ctctcctgca gggccagtca gactgttggc agcgccttag cctggtacca gcagaaacct
      241 gggcagacgc acaaactcct cattaatggt gcatccagca gggccaccgg catcccagac
      301 aggttcagtg gcagtgggtc tggaacagag ttcactctca ccatcagtag tccggagcct
      361 gaggatgttg gagtttatta ctgtcagcag gattttggct ggcctccgac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01005352             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9142:9095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005352
VERSION     KCVT01005352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9142:9095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82877.1"
                     /translation="CQQYDSDLFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          113 c          111 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatttgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacctg ttcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005353             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14332:13298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005353
VERSION     KCVT01005353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14332:13298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..327
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82878.1"
                     /translation="CLQGYITPYSF"
     J_segment       328..365
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           94 a           89 c           96 g           89 t
ORIGIN      
        1 acatggggtg gtatcaacgc aagagtacat gggtgccaga tgtgacttcc agatgaccca
       61 gtctccatct tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag
      121 tcaggacatt agcgattttt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg
      181 cctgatttat gctgcatcca gtttgcaaag tggggtcccg tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcggctta
      301 ttactgtcta cagggttata ttaccccgta cagttttggc caggggacca aagtggagat
      361 caaacgag
//
LOCUS       KCVT01005354             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13293:10169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005354
VERSION     KCVT01005354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13293:10169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82879.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagtcccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005355             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19990:3863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005355
VERSION     KCVT01005355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19990:3863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..261
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82880.1"
                     /translation="CQQYDSDSLSF"
     J_segment       266..303
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>306
                     /gene="IGKC"
BASE COUNT           78 a           74 c           83 g           71 t
ORIGIN      
        1 acatgggctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
       61 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      121 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      181 ctgggacaga attcactctc accatcagca gcctggagcc tgaagatttt gcaacttatt
      241 actgtcaaca gtatgacagt gattcgctca gtttcggtgg agggaccaag gtggagatca
      301 aacgag
//
LOCUS       KCVT01005356             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21675:14814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005356
VERSION     KCVT01005356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21675:14814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82881.1"
                     /translation="CMQALEFPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tgttgggttt tattattgca tgcaagctct agagtttcct cccactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005357             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20317:14066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005357
VERSION     KCVT01005357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20317:14066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..408
                     /note="immunoglobulin light chain variable region"
     V_region        125..408
     V_segment       125..371
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <348..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82882.1"
                     /translation="CMQALEFPLTF"
     J_segment       374..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>411
                     /gene="IGKC"
BASE COUNT           93 a          105 c          112 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccat ctcctgtagg tctagtcaga gcctcttgga tagtgaagat ggaaatacct
      181 atttggaatg gcaccggcag atgccaggcc agtctccaca gctcttgatt tatgaggttt
      241 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      301 ctctgaaaat ctgcagagtg gaggctgagg atgttggggt ttattactgc atgcaagctc
      361 tagagtttcc tctgacgttc ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005358             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21821:14957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005358
VERSION     KCVT01005358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21821:14957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82883.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          122 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacatct atttggactg gtacctgcag aggccaggcc
      241 agtctcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgaattca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005359             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9039:11999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005359
VERSION     KCVT01005359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9039:11999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82884.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          118 c          125 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagcggggac gtagtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagtc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgggga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005360             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:28273:14884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005360
VERSION     KCVT01005360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:28273:14884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82885.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005361             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15956:16556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005361
VERSION     KCVT01005361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15956:16556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82886.1"
                     /translation="CQQGYSYPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          119 c          109 g           93 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 gccattggca ataatttaaa ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atctctaagg catccagttt gcaaagtggg attccctctc ggctcagcgg cagtggatct
      301 ggggcggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttactac
      361 tgtcaacagg gttatagtta cccgtggaca ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005362             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20710:18766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005362
VERSION     KCVT01005362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20710:18766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82887.1"
                     /translation="CQQHDNSPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          118 c          110 g           90 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagct tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctctc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggtg
      181 ttagcgactg gttggcctgg tatcaacaga gaccagggaa agcccctaaa ctcctgatct
      241 atagggcgtc caatttggat acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcttgc agcctgaaga tatcgctaca tattactgtc
      361 aacagcatga taattcccct ccgacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005363             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:25100:15095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005363
VERSION     KCVT01005363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25100:15095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82888.1"
                     /translation="CQQYNSDLFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          113 c          110 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatttg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccattttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc tgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005364             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19075:3995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005364
VERSION     KCVT01005364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19075:3995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82889.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          118 c          108 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga cgtccagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca gagtcaccat cacttgcaca gccagtcacg
      181 atattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005365             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13608:8233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005365
VERSION     KCVT01005365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13608:8233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82890.1"
                     /translation="CQQYNSLPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          107 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccgtcaag gttcagtggc agtgcatctg
      301 ggacagaatt cgctctcacc atcagcagcc tgcaacctga agattttgct acttatcact
      361 gtcaacagta taatagttta cctctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005366             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20429:16640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005366
VERSION     KCVT01005366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20429:16640"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82891.1"
                     /translation="CLQGDTAPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          115 c          114 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggcaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcattaac gattatttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggtgatactg ccccgttcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005367             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17793:14457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005367
VERSION     KCVT01005367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17793:14457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82892.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacta tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01005368             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17445:19237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005368
VERSION     KCVT01005368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17445:19237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..317
                     /note="immunoglobulin light chain variable region"
     V_region        1..317
     V_segment       1..298
                     /gene="IGKV2-82"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <276..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82893.1"
                     /translation="CMQGAQFPLTF"
     J_segment       301..317
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           70 a           89 c           83 g           75 t
ORIGIN      
        1 acatggggat gacacagact ccactctccc tgcccgtcac ccctggagag ccggcctcca
       61 tctcctgcag gtctagtcag agcctcccgc acaaagatgg aaacacatat ttgtattggt
      121 acctgcagag gccgggccag tctccacagc tcctgatata ttttgcttca taccgggcct
      181 ctggagtccc agacaggttc agtggaagtg ggtcgggcac tgatttcaca ctacgaatca
      241 gtagggtgga agctgaggat attggagttt atttttgcat gcaaggagca cagtttccac
      301 tcactttcgg ccccggg
//
LOCUS       KCVT01005369             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11829:22018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005369
VERSION     KCVT01005369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11829:22018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82894.1"
                     /translation="CQQYNSLPLTF"
     J_segment       377..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          105 a          108 c          107 g           97 t
ORIGIN      
        1 acatggggac ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctggggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct
      121 ccctgtctgc atctctgggg gacagagtca ccatcacttg ccgggcaagt caggacatta
      181 gcagatattt aaattggtat cagcagaaac cggggaaagc ccctaagttc ctgatctatt
      241 atgtaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat tattgtcaac
      361 agtataatag tttaccgctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005370             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24736:14407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005370
VERSION     KCVT01005370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24736:14407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82895.1"
                     /translation="CQHSHGSPITF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          114 c          109 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggat atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgtttac aactatttac attggtatca gcagaaacca gggaaagccc ctaaggtcct
      241 gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggactgat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005371             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:27432:14120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005371
VERSION     KCVT01005371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:27432:14120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82896.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc catggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005372             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20858:16582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005372
VERSION     KCVT01005372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20858:16582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82897.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          125 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005373             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8789:15852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005373
VERSION     KCVT01005373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8789:15852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82898.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          125 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt cccttggacg ttcggccaag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005374             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24857:14326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005374
VERSION     KCVT01005374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24857:14326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82899.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggaca cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005375             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14055:18779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005375
VERSION     KCVT01005375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14055:18779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82900.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          124 c          118 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggac ttattactgc atccaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005376             272 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:27440:7368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005376
VERSION     KCVT01005376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 272)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:27440:7368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..231
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <209..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82901.1"
                     /translation="CMQSLEFPLTF"
     J_segment       232..269
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>272
                     /gene="IGKC"
BASE COUNT           68 a           58 c           81 g           65 t
ORIGIN      
        1 acatgggcag agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca
       61 gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt
      121 cccagacagg ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt
      181 ggaggctgag gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt
      241 cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005377             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:6681:16404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005377
VERSION     KCVT01005377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6681:16404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82902.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcac ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005378             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20114:4571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005378
VERSION     KCVT01005378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20114:4571"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82903.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcatc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005379             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14310:17291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005379
VERSION     KCVT01005379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14310:17291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82904.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          116 c          108 g           89 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagtcag
      181 gatattaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcggtgg aagtggatct
      301 gggacagatt tcactctcac cattagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005380             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12336:22017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005380
VERSION     KCVT01005380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12336:22017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..372
                     /note="immunoglobulin light chain variable region"
     V_region        79..372
     V_segment       79..334
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82905.1"
                     /translation="CLQSKNSPWSF"
     J_segment       335..372
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>375
                     /gene="IGKC"
BASE COUNT           93 a           98 c          100 g           84 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccagggcaga gggccaccat cacctgcaga gccagtgaga
      121 gtgtcagtgc ctttggaata agcctcattc actggtatca acagaaacca ggacaacctc
      181 ctaaactcct gatttaccaa gcaatcaata aggagactgg ggtcccagcc aggttcagcg
      241 gcagtgggtc tgggaccgat ttcaccctca caattaatcc tgtggaacct gacgatggtg
      301 cagattatta ctgtctgcag agtaagaatt ctccgtggtc gttcggccaa gggaccaagg
      361 tggaaatcaa acgag
//
LOCUS       KCVT01005381             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11505:17150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005381
VERSION     KCVT01005381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11505:17150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82906.1"
                     /translation="CQQHDNAPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          116 c          114 g           85 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagag
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaggccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcagca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcagcagcat gacaatgccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01005382             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10925:16194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005382
VERSION     KCVT01005382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10925:16194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..411
                     /note="immunoglobulin light chain variable region"
     V_region        95..411
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82907.1"
                     /translation="CQQYHSLPLTF"
     J_segment       380..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>419
                     /gene="IGKC"
BASE COUNT          100 a          117 c          106 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgttg gagacagagt caccgtcact tgccgggcaa gtcaggacat
      181 cagcacttat ttaaattggt atcagcagaa accggggaaa gcccctaacc tcctgatctt
      241 ttattcaaac cgtttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat cttgcaactt attactgtca
      361 acagtatcac agtttacctc tcactttcgg cggagggacc aaggtggaga tgacacgag
//
LOCUS       KCVT01005383             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12328:17386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005383
VERSION     KCVT01005383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12328:17386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82908.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacc aatgatttag cctggtatca acagagacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tgaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagt ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005384             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10461:14209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005384
VERSION     KCVT01005384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10461:14209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82909.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtccct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgccggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggtatt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005385             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19561:18145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005385
VERSION     KCVT01005385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19561:18145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..412
                     /note="immunoglobulin light chain variable region"
     V_region        94..412
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82910.1"
                     /translation="CQQHNSYPLTF"
     J_segment       379..412
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>418
                     /gene="IGKC"
BASE COUNT          104 a          120 c          105 g           89 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag tcagggcatt
      181 accaatgatt tagcctggta tcagcagaaa ccagggaaag ccccgaagcc cctgatctat
      241 tacgcatcca atttggaaac tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagcataata gttacccact cactttcggc ggagggacca aggtggagat cagacgag
//
LOCUS       KCVT01005386             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11645:13892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005386
VERSION     KCVT01005386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11645:13892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82911.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttt ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005387             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12088:7486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005387
VERSION     KCVT01005387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12088:7486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82912.1"
                     /translation="CLQGDTSPFTF"
     J_segment       388..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaacg attatttaag ttggtatcac cagaaaccag gaaaacctcc taagcgcctg
      241 atctatgctg catccagttt ggagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac cattagcagc ctgcagtctg aagattttgc aacttattac
      361 tgtctacagg gtgatacttc cccgtttact ttcggcggag ggacccaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005388             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9056:15371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005388
VERSION     KCVT01005388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9056:15371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82913.1"
                     /translation="CQHSHGSPITF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgtttac aactatttac attggtatca gccgaaacca gggaaagccc ctaaggtcct
      241 gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggactgat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005389             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14176:5674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005389
VERSION     KCVT01005389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14176:5674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82914.1"
                     /translation="CQQYDSFPLTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>421
                     /gene="IGKC"
BASE COUNT           99 a          112 c          113 g           97 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca ttcagatgac ccagtctcct
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 attagcagtt atttaaattg gtatcagcag aaaccgggga aagcccctaa ggtcctgatc
      241 tattttgcaa accgtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg gaacctgagg attttgccac ttatcactgt
      361 caacagtatg atagtttccc gctcactttc ggtgggggga ccaaggtgga gatcagacga
      421 g
//
LOCUS       KCVT01005390             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14725:13299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005390
VERSION     KCVT01005390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14725:13299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..378
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82915.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          125 c          111 g           86 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgctgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca acttagcctg gtaccagcag agacctgggc agtctcccag actcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccaggcaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      361 cagcagaaca gtaactggcc tctcactttc ggtggaggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01005391             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9362:19238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005391
VERSION     KCVT01005391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9362:19238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82916.1"
                     /translation="CQHSYGTPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          113 c          105 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtaggacaa gtcagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcgtcc aatttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ttcaccatca ccagcctgca acctgaagat gttgcaactt attactgtca
      361 gcatagttat ggtaccccgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005392             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:3609:11522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005392
VERSION     KCVT01005392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3609:11522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82917.1"
                     /translation="CLQYKSYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          115 c          107 g          101 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gcccgatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcttc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 ggtcttagca gttctttaca ttggtttcaa cacaaaccag ggaaagcccc taggctcctg
      241 atctatgctg catccagttt ggcaggtggg gtcccattaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagaagc ctacagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaagtta cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005393             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15871:7759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005393
VERSION     KCVT01005393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15871:7759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82918.1"
                     /translation="CIQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acaactcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtct gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcattcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005394             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11587:11373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005394
VERSION     KCVT01005394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11587:11373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82919.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          118 c          111 g           90 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtccgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005395             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13128:4441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005395
VERSION     KCVT01005395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13128:4441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82920.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag taatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca acataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005396             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20878:3402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005396
VERSION     KCVT01005396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20878:3402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82921.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          117 c          123 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggga gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005397             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:21551:13866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005397
VERSION     KCVT01005397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21551:13866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82922.1"
                     /translation="CMQSLDFPLSF"
     J_segment       406..437
                     /gene="IGKJ5-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctctccttc ggccaaggga
      421 cacgactgga gattaaatga g
//
LOCUS       KCVT01005398             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23981:13158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005398
VERSION     KCVT01005398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23981:13158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82923.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggaggc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01005399             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10950:4271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005399
VERSION     KCVT01005399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10950:4271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82924.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagtttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcaacag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005400             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9355:8313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005400
VERSION     KCVT01005400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9355:8313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82925.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatgggggg tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005401             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13725:18123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005401
VERSION     KCVT01005401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13725:18123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82926.1"
                     /translation="CQQYDSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          113 c          107 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcaattat ttaaattggt atcaggagaa accggggaaa gcccctaagc ccctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagta gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt actactgtca
      361 acagtatgat tctttaccgt ggacgttcgg ccaagggacc aaggtggaca tcaaacgag
//
LOCUS       KCVT01005402             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21257:8941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005402
VERSION     KCVT01005402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21257:8941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82927.1"
                     /translation="CQQVYSNPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          111 c          107 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgaaatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt catcatctct tgccgggcaa gtcagaacat
      181 ttatagtcat ttagcgtggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 tgctgcatcc agattgcaaa gtgggcttcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctggaattt attactgtca
      361 acaagtttat agcaatccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005403             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:26119:11325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005403
VERSION     KCVT01005403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:26119:11325"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..393
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82928.1"
                     /translation="CLQHKSFPYTF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          113 a          122 c           98 g          101 t
ORIGIN      
        1 acatggggct tcttgcagga gtcagacaca gtcaggacac agcatggaca tgagggcccc
       61 cgctcatctc ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat
      121 gactcagtct ccatcttccc tgtctgcatc tgtgggagac actgtcacca tcacttgccg
      181 gacaagtcaa ggtattacca attatttaca ttggtttcaa cagaaaccag ggaaagcccc
      241 taaactcctg atctatgaaa catccagttt gacaagtggg gtcccatcaa ggttcagcgg
      301 cagcgcatct gggacagaat tcactctcac catcagcagc ctgcaccctg aagattttgc
      361 aacttattac tgtctacagc ataaaagttt cccgtacact tttggccagg ggaccaaact
      421 ggagatcaaa cgag
//
LOCUS       KCVT01005404             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7573:17854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005404
VERSION     KCVT01005404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7573:17854"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..441
                     /note="immunoglobulin light chain variable region"
     V_region        120..441
     V_segment       120..403
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82929.1"
                     /translation="CQQYDSFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          111 a          123 c          106 g          104 t
ORIGIN      
        1 acatgggggc tggacagact tcatgcagga gtcagaccca gtcaggacac agcatggaca
       61 tgagggtccc cgctcagctc ctggggctcc tgctgctctg gctcccaggt gccagatgtg
      121 acattcagat gacccagtct ccatcctccc tgtctgcttc tgtaggagac agagtcacca
      181 tcacttgccg ggcaagtcag gacattagca gttatttaaa ctggtatcag cagaaaccgg
      241 ggaaagcccc ttacctcctg atctattata caaatcgttt ggaaactggg gtcccatcaa
      301 ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc ctccaacctg
      361 aagattttgc aacttattac tgtcaacagt atgatagttt tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01005405             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17592:11221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005405
VERSION     KCVT01005405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17592:11221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82930.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcagact cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005406             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20315:6944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005406
VERSION     KCVT01005406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20315:6944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82931.1"
                     /translation="CQQVYSSPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          114 c          106 g          105 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccagatg acccagtctc
      121 catctgcctt gtctgcatct gtgggagaca gattcaccat ctcttgccgg gcaagtcaga
      181 acatttatag ttatttagcg tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatgctgt atccagattg caaagtgggg ttccctctcg gttcagcggc agtggaactg
      301 ggacagattt cactctcagc atcagcagcc tacagcctga agattctgcc ggttattact
      361 gtcaacaggt ttatagtagt ccattcactt tcggccccgg gaccaaactg gctatcaaac
      421 gag
//
LOCUS       KCVT01005407             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9424:7374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005407
VERSION     KCVT01005407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9424:7374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82932.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          119 c          106 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccagatg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005408             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22291:9779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005408
VERSION     KCVT01005408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22291:9779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82933.1"
                     /translation="CQQYNSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          113 c          112 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005409             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20434:7063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005409
VERSION     KCVT01005409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20434:7063"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82934.1"
                     /translation="CMQALDFPYSF"
     J_segment       406..442
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          108 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg agtggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttttgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag tgtggaggct
      361 gaggatgttg gggtctatta ctgcatgcaa gctctagact ttccttacag ttttggccag
      421 gggaccaaag tggagattaa acgag
//
LOCUS       KCVT01005410             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8105:4666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005410
VERSION     KCVT01005410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8105:4666"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82935.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          127 c          112 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggaggac cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacatgcag aagccaggcc
      241 agtctccaca tctcttgatt tatggggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat cagcagagtg gagtctgagg
      361 atcttggggt ttactactgc atgcaagctc tagagtttcc cttcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005411             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13959:15938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005411
VERSION     KCVT01005411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13959:15938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82936.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agagccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005412             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10719:4855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005412
VERSION     KCVT01005412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10719:4855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82937.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          120 c          105 g           89 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ttggttggcc tggtatcaac agaaaccagg aaaagcccct aacctcctga
      241 tctatagggc atccaatttg gaaacagtgg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005413             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17766:10570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005413
VERSION     KCVT01005413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17766:10570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..332
                     /note="immunoglobulin light chain variable region"
     V_region        11..332
     V_segment       11..288
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <272..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82938.1"
                     /translation="SMHDYGWPTTF"
     J_segment       298..332
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>335
                     /gene="IGKC"
BASE COUNT           88 a           90 c           86 g           71 t
ORIGIN      
        1 acatggggga gacatcatcc tgaaccagac gccagcatcc ctgactgcac ctccaggaga
       61 gacagtctcc atctcctgcc aagccagagc agatgtacat ggtgaaatat cttggatccg
      121 gataaacctt gaacaaagac ttgaacccca tttatctcat gtcactacct tggccccagg
      181 tgtcgcagac cggttcatca gcaaggggag tggcaccagt tatgttttca gcatcagtga
      241 cctgcagcct ggggactctg gggactatta ctccatgcat gactatgggt ggccaaccac
      301 tttcggtgga gggaccaagg tggagatcaa acgaa
//
LOCUS       KCVT01005414             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21648:24356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005414
VERSION     KCVT01005414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21648:24356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82939.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005415             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12925:10655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005415
VERSION     KCVT01005415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12925:10655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..424
                     /note="immunoglobulin light chain variable region"
     V_region        85..424
     V_segment       85..386
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82940.1"
                     /translation="CMQALEFPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           95 a          118 c          112 g          102 t
ORIGIN      
        1 acatggggag gtcacctcct cacaatgagg ctccctgctc agctcctggg actgctaatg
       61 ctctggctcc ctggatccac tggggacatt gtgatgaccc agactccact ctccctgccc
      121 gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct cttggatagt
      181 gaggatgaaa acacctattt ggaatggtac ctgcagaagc caggccagtc tccacagctc
      241 ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag tggcagtggg
      301 tcagacactg atttcacact gaaaatcagt agagtggagg ctgaggatgt tggggtttat
      361 tactgcatgc aagctctaga gtttccattc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01005416             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11428:13833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005416
VERSION     KCVT01005416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11428:13833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82941.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgta tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005417             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:9086:13334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005417
VERSION     KCVT01005417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9086:13334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82942.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          107 c          109 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgtaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005418             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20219:5779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005418
VERSION     KCVT01005418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20219:5779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82943.1"
                     /translation="CMQAPEFPWTF"
     J_segment       348..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           86 a           99 c          112 g           90 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccagt ctccctgccc gtcaccctgg gagagccggc ctccatctcc tgccggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggcac ctgcagaggc
      181 caggccagtc tccacagctc ttgatttatg aggtttccta tcgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tggtatttat tactgcatgc aagctccaga gtttccttgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01005419             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20211:3745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005419
VERSION     KCVT01005419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20211:3745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82944.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgttg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005420             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10620:12929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005420
VERSION     KCVT01005420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10620:12929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..425
                     /note="immunoglobulin light chain variable region"
     V_region        102..425
     V_segment       102..385
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82945.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       395..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>432
                     /gene="IGKC"
BASE COUNT          101 a          116 c          114 g          101 t
ORIGIN      
        1 acatgggggg gagttagacc cagtctggac gcagcatgga catcagggtc ctcgctcagc
       61 ttctcgggct cctgctgctc tggctcccag gtgccagatg tgacattcag ttgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcaagtc
      181 aggacattgg caattattta gcctggtatc agcagaaacc agggaaagcc cctaacctcc
      241 tgatctataa ggcgtccagt ttacaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcagtttatt
      361 actgtcaaca gcgtaatagt tacccgtaca tgtgcagttt tggcccgggg accaaagtgg
      421 agatccgacg ag
//
LOCUS       KCVT01005421             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17620:17494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005421
VERSION     KCVT01005421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17620:17494"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..422
                     /note="immunoglobulin light chain variable region"
     V_region        99..422
     V_segment       99..382
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82946.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       392..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>429
                     /gene="IGKC"
BASE COUNT          101 a          116 c          111 g          101 t
ORIGIN      
        1 acatggggag ttagacccag tctggacgca gcatggacat cagggtcctc gctcagcttc
       61 tcgggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagttg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcaagtcagg
      181 acattggcaa ttatttagcc tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctataaggc gtccagttta caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca gtttattact
      361 gtcaacagcg taatagttac ccgtacatgt gcagttttgg cccggggacc aaagtggaga
      421 tccgacgag
//
LOCUS       KCVT01005422             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13162:11271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005422
VERSION     KCVT01005422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13162:11271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82947.1"
                     /translation="CQQYNDVLFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          112 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc cgggccagtg
      181 agagtgttgg caactactta ccctggtacc agcagaaacc tggccaggct cccaagctcc
      241 ttgtccatgg tgcatacttc agggccgctg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga attcactctc accattagca gcctggagcc tgaggatgtt ggagtttatc
      361 actgtcagca gtataatgac gtcctattca ctttcggccc cgggacgaaa gtggacatca
      421 aacgag
//
LOCUS       KCVT01005423             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14401:14478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005423
VERSION     KCVT01005423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14401:14478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82948.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcgctctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005424             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20558:15316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005424
VERSION     KCVT01005424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20558:15316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82949.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctacat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005425             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20228:15865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005425
VERSION     KCVT01005425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20228:15865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82950.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          118 c          108 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc ctcgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005426             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21085:12800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005426
VERSION     KCVT01005426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21085:12800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82951.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggacatcaa
      421 acgag
//
LOCUS       KCVT01005427             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19622:8834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005427
VERSION     KCVT01005427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19622:8834"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82952.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcgct cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gtctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc gctcactttc ggcggaggga
      421 ccaaggtgga gctcaaacga g
//
LOCUS       KCVT01005428             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22994:20424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005428
VERSION     KCVT01005428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22994:20424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82953.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc acagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005429             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16511:3012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005429
VERSION     KCVT01005429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16511:3012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82954.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           85 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005430             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14051:5362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005430
VERSION     KCVT01005430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14051:5362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82955.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          117 c          124 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactgtccc tgcccgtcac ccttggagag ccggcctcca tctcctgtgg gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg actctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005431             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14637:3431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005431
VERSION     KCVT01005431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14637:3431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82956.1"
                     /translation="CQQVYGNPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          117 c          108 g          101 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtct
      121 ccatctgcct tgtctgcatc tgggggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata gttatttagc gtggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatggta catccagatt gcaaagcggg attccctctc ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattctgc cgcttattac
      361 tgtcaacagg tttatggtaa cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01005432             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12990:10521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005432
VERSION     KCVT01005432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12990:10521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82957.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagt cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005433             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14779:13309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005433
VERSION     KCVT01005433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14779:13309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..400
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82958.1"
                     /translation="CMQDIQLPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          124 c          119 g          105 t
ORIGIN      
        1 acatgggact gatcaggact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctggggctg ctggtgctct ggctccctgg gaccagtggg gatattgtga tgactcagac
      121 tccactctcc ctgtccgtca cccctggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctccag catagaaatg gatacaccta tttgttttgg tacctacaga agccaggcca
      241 gtctccacaa ctcctgatct atttgggttc caaccgggcc tctggagtcc cagacaggtt
      301 cagcggcagt gggtcaggca ctgatttcac attgcaaatc agccgggtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagatat acagcttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005434             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:25816:6054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005434
VERSION     KCVT01005434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25816:6054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..457
                     /note="immunoglobulin light chain variable region"
     V_region        118..457
     V_segment       118..419
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <397..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82959.1"
                     /translation="CMQALEFPLTF"
     J_segment       420..457
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>460
                     /gene="IGKC"
BASE COUNT          104 a          124 c          127 g          105 t
ORIGIN      
        1 acatggggca acgcagagta catgggggat cacgactcct caggtcacct tctcacaatg
       61 aggctccctg ctcagctcct gggactgcta atgctctggc tccctggatc cagtggggac
      121 attgtgatga cccagactcc actctccctg cccgtcaccc ttggagagcc ggcctccatc
      181 tcctgcaggt caagtcagag cctcctggat agtgaggatg gaaacaccta tttgcactgg
      241 tacttgaaga agccaggcca gtctccacag ctcttaattt atgaggtttc caaccgggcc
      301 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      361 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct agagtttccg
      421 ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005435             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15595:9215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005435
VERSION     KCVT01005435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15595:9215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82960.1"
                     /translation="CQHSYGTPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          114 c          106 g           99 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtag gacaagtcag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taggctcctg
      241 atctatgctg cgtccaattt gcaaagtgtg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactttcac catcaccagc ctgcaacctg aagatgttgc aacttattac
      361 tgtcagcata gttatggtac cccgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005436             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22560:10028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005436
VERSION     KCVT01005436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22560:10028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82961.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          125 c          114 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtactg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcttagcc tggtaccagc agagacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccaggcag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa cagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005437             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25885:19031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005437
VERSION     KCVT01005437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25885:19031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82962.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggaatc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005438             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:24588:16920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005438
VERSION     KCVT01005438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24588:16920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82963.1"
                     /translation="CMQAREFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          126 c          117 g          101 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttcg atagtgagga ggggaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtc tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgctgggg tttattactg catgcaagct cgagagtttc cattcacttt cggccccggg
      421 accaaactgg acatcaaacg ag
//
LOCUS       KCVT01005439             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13773:5864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005439
VERSION     KCVT01005439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13773:5864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82964.1"
                     /translation="CIQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          110 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cttctcctgt aggtctagtc
      181 acagcctctt ggatagtgag gatggaaata tccatttgga ttggtatctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggtttagtgg cagtgggtca gacactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttactac tgcatacagt ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005440             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9405:17627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005440
VERSION     KCVT01005440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9405:17627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82965.1"
                     /translation="CQQGSPFPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          112 c          108 g           95 t
ORIGIN      
        1 acatggggat gagcaaaact gacaagtcaa ggcaggaaga tgttgtctcc atcacaactc
       61 attgggtttc tgctgctctg ggttccagcc tccaagggtg aaattgtgct gactcagtct
      121 ccagcctttc ggtctgtgac tctaaaggag aaagtcacca tcacctgcca ggccggtcag
      181 agcattggta atagcttaca ctggtaccag cagaaaccgg atcagtctcc aaagctcctc
      241 atcaaatatg cttcccagtc catctcaggg gtcccctcaa ggttcagtgg cagtggatct
      301 gggacagatt tcaccctcac catcaacagc ctggaagctg aagatgctgc gacgtattac
      361 tgtcagcagg gaagtccttt cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005441             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10440:17450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005441
VERSION     KCVT01005441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10440:17450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82966.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aggcccttga
      241 tctattccgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc cgtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005442             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14246:17579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005442
VERSION     KCVT01005442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14246:17579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82967.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcatc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005443             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9011:7680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005443
VERSION     KCVT01005443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9011:7680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82968.1"
                     /translation="CQQYNSEPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          113 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagag gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg agccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005444             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8242:10454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005444
VERSION     KCVT01005444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8242:10454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    71..348
                     /note="immunoglobulin light chain variable region"
     V_region        71..348
     V_segment       71..306
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82969.1"
                     /translation="CQQYDSDSLTF"
     J_segment       311..348
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           89 a           92 c           93 g           77 t
ORIGIN      
        1 acatgggagg acacagcatg gacatgaggg tccccgctca gctcctagga ctcctgctgc
       61 tctgtctccc aggagacaga gtcaccatca cttgtcgggc gactcaggac attcgcagtt
      121 atttagcgtg gtatcagcag aaaccaggga aagccccgag gcccttgatc tattacgcgt
      181 ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctgga acagaattca
      241 ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt caacaatatg
      301 acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005445             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18106:3448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005445
VERSION     KCVT01005445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18106:3448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82970.1"
                     /translation="CEQYNSLPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          111 a          112 c          101 g           96 t
ORIGIN      
        1 acatggggca gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttaacattta tttaaattgg tatcaccaga aaccggggaa agcccctaag ctcctgatct
      241 attatacaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcaact tattactgtg
      361 aacaatacaa tagtttaccg tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01005446             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18985:8373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005446
VERSION     KCVT01005446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18985:8373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82971.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          119 c          106 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaat tcaaacgag
//
LOCUS       KCVT01005447             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17962:6878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005447
VERSION     KCVT01005447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17962:6878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82972.1"
                     /translation="CLQGYIIPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          110 c          111 g          100 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt ggaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattat
      361 tgtctacagg gttatattat cccgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005448             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:23010:19957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005448
VERSION     KCVT01005448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23010:19957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82973.1"
                     /translation="CQQHNTYPLTF"
     J_segment       387..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          102 g           95 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 acattagtaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tgtattacgc atccaatttg gaaaatgggg tcccatcaag gttcagtggt agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca agttattact
      361 gtcaacagca taatacttac ccattgactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01005449             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:24354:10265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005449
VERSION     KCVT01005449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24354:10265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82974.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tgctggggat ggatacacct atttggattg gcacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005450             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10840:7555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005450
VERSION     KCVT01005450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10840:7555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82975.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac gctgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga gatcaaacga g
//
LOCUS       KCVT01005451             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16998:17420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005451
VERSION     KCVT01005451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16998:17420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..415
                     /note="immunoglobulin light chain variable region"
     V_region        96..415
     V_segment       96..380
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82976.1"
                     /translation="CQQHNSYPRTF"
     J_segment       382..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>420
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           92 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtacca gatgtgacat ccagatgacc cagtctccat
      121 cttccttgtc tgcatctgta ggagacagag tcaccatcac tttccaagcc agtcagggta
      181 ttggcaactg gttagcctgg tatcggcaga aaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc cagtttacaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 agcagcataa tagttatcct cggacgttcg gccaagggac caaggtggaa atcaagcgag
//
LOCUS       KCVT01005452             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11383:15066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005452
VERSION     KCVT01005452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11383:15066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..377
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82977.1"
                     /translation="CQQHDDSPRTF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          108 a          117 c          106 g           86 t
ORIGIN      
        1 atggggagtc tcagacagga cacagcatgg acacgagggt ccccgctcag ctcctggggc
       61 tcctgttgct ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct
      121 ccctgtctgc atctgtagga gacagagtca ccatcacttg cacagccagc cacgatataa
      181 ataactggtt ggcctggtat caacagaaac caggaaaagc ccctaagctc ctgatctata
      241 gggcatccaa tttggaaaca ggggtcccat cgaggttcag tggaagtgga tctgggacag
      301 atttcactct caccatcagc agcctgcagc ctgaagattt cgcaacatat tactgtcaac
      361 agcatgatga ttcccctcgg acgttcggcc aagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005453             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18942:5846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005453
VERSION     KCVT01005453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18942:5846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82978.1"
                     /translation="CLQGYITPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          112 c          112 g          100 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacttccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tgcaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ttgtctacag ggttatatta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005454             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11667:7863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005454
VERSION     KCVT01005454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11667:7863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82979.1"
                     /translation="CQQYNSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          114 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagca gttatttagc gtggtatcgg cagaagccag ggaaggcccc ggagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga ctcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005455             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15278:19408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005455
VERSION     KCVT01005455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15278:19408"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82980.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctacagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005456             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8162:10620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005456
VERSION     KCVT01005456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8162:10620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82981.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005457             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24437:15824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005457
VERSION     KCVT01005457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24437:15824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82982.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005458             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:27954:10938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005458
VERSION     KCVT01005458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:27954:10938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82983.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005459             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14718:13385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005459
VERSION     KCVT01005459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14718:13385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82984.1"
                     /translation="CMQGTHLPFTF"
     J_segment       393..430
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          120 c          110 g          103 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcta tcactcttgg acaaccggcc tccatttcct gcaggtctag tcacaccctt
      181 gtacacagtg atgggaaaac ctacttgaat tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatcaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttgga
      361 gtttattact gcatgcaagg tacacacctt ccattcactt tcggccccgg gaccaaactg
      421 gatatcaaac gag
//
LOCUS       KCVT01005460             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22905:10752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005460
VERSION     KCVT01005460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22905:10752"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82985.1"
                     /translation="CQQYDSFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          116 c          100 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatac aaatcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatagtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01005461             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19766:4278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005461
VERSION     KCVT01005461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19766:4278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..240
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82986.1"
                     /translation="CQQHNNYSPTF"
     J_segment       253..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           81 a           71 c           75 g           63 t
ORIGIN      
        1 acatggggta ggagacacag tcaccatcac ttgtcgggca agtcagggca taagcaatga
       61 tttagcctgg tatcagctga aaccagggaa agccccgagg cccctgatgt attacgcatc
      121 caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagatttcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagcataa
      241 taattactct cccactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005462             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15427:10503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005462
VERSION     KCVT01005462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15427:10503"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82987.1"
                     /translation="CQQGNSNPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          111 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtttc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tatactatgg aaaaagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaccagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtaat cctctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005463             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12476:20147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005463
VERSION     KCVT01005463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12476:20147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..277
                     /note="immunoglobulin light chain variable region"
     V_region        9..277
     V_segment       9..239
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82988.1"
                     /translation="CQQYNSYPLTF"
     J_segment       240..277
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           74 a           71 c           69 g           66 t
ORIGIN      
        1 acatgggcag tcaccatcac ttgtcgggca agtcaggaca ttagcagtta tttagcctgg
       61 tatcagcaga aaccagggag agcccctaag cgcctgatct atgctgcatc ctctttgcaa
      121 agtggggtcc catcaagctt cagcggcagt ggatctggga cagatttcac tctcaccatc
      181 agcagcctac agcctgaaga ttttgcaact tattactgtc aacagtataa tagttatccg
      241 ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005464             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13284:7675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005464
VERSION     KCVT01005464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13284:7675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82989.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtagagatca
      421 gacgag
//
LOCUS       KCVT01005465             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20774:11040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005465
VERSION     KCVT01005465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20774:11040"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82990.1"
                     /translation="CQQYNSDPRTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          120 c          113 g           89 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cctgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ctactgtcaa caatataaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005466             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13362:14962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005466
VERSION     KCVT01005466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13362:14962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82991.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccatttt ggaaagtggg gtcccatcaa ggttcagcgc cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005467             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13292:16669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005467
VERSION     KCVT01005467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13292:16669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82992.1"
                     /translation="CQQYSDFLLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           94 a          123 c          114 g           91 t
ORIGIN      
        1 atggggggaa ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctgga tcccagatac cgccggagaa attgtaatga cgcagtctcc
      121 agccaccctg tctttgtctc caggggaaac agccaccctc tcctgcaggg ccagtgagag
      181 tgttggcacc ttcgtagcct ggtaccaaca gaaacctggg caggctccca ggctccttgt
      241 ccatagtgca ttcttcaggg ccactggcat cccagacagg ttcagtggca gcgggtctag
      301 gacagagttc actctcacca ttaacaccct ggagcctgag gatgttggac tttatcactg
      361 tcagcagtat agtgacttcc tgctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005468             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6792:7923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005468
VERSION     KCVT01005468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6792:7923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..422
                     /note="immunoglobulin light chain variable region"
     V_region        83..422
     V_segment       83..384
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82993.1"
                     /translation="CMQALDFPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           93 a          121 c          110 g          101 t
ORIGIN      
        1 acatgggggt caccttctca caatgaggct ccctgctcag ctcctgggac tgctaatgct
       61 ctggctccct ggatccagtg gggacattgt gatgacccag actcccccct ccctgcccgt
      121 cacccttgga gaggcggcct ccatctcctg taggtctagt cagagcctct tcgatactga
      181 agaaggaaac acctatttgg agtggtacct gcagaggcca ggccagactc cacagctctt
      241 gatttatcag gtttccaatc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      301 agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg gactttatta
      361 ctgcatgcag gctctagact ttccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01005469             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21918:9837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005469
VERSION     KCVT01005469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21918:9837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..399
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82994.1"
                     /translation="CLQDIQLPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           88 a          123 c          122 g          107 t
ORIGIN      
        1 acatgggggt gatcaggact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctggggctg ctggtgctct ggctccctgg gaccagtggg gatattatga tgactcagac
      121 tccactctcc ctgtccgtca cccctggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcctg cataggaatg ggtacaccta tttgttttgg tacctgcaga agccaggcca
      241 gtctccacag ctcctgatct atttcggttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtgccagt gggtcaggca ctgatttcac actgaaaatc agccgggtgg aggctgagga
      361 tgttggggtt tattactgct tgcaagatat acaacttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005470             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19191:12265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005470
VERSION     KCVT01005470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19191:12265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82995.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct acccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005471             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13712:10868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005471
VERSION     KCVT01005471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13712:10868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82996.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          109 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc gaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005472             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6722:15708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005472
VERSION     KCVT01005472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6722:15708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82997.1"
                     /translation="CLQYNSSPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacat agcatggaca tgagggtccc tgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgccg ggcgagtcag
      181 actattagca gctggttaga ctggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctttaagg catccagttt gcaaagtggg gtcccctcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtctacagt acaatagtag cccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005473             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15295:17821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005473
VERSION     KCVT01005473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15295:17821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..363
                     /note="immunoglobulin light chain variable region"
     V_region        86..363
     V_segment       86..325
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82998.1"
                     /translation="CQQYNSDPRTF"
     J_segment       329..363
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT           91 a           99 c           99 g           77 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggag acagagtcac catcacttgt cgggcgagtc
      121 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      181 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcactggat
      241 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      301 tctgtcaaca gtataacagt gacccgcgca ctttcggtgg agggaccaag gtggagatca
      361 aacgag
//
LOCUS       KCVT01005474             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15552:10499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005474
VERSION     KCVT01005474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15552:10499"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV82999.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>423
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattaggag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aaggccttga
      241 tctattacac atccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttattact
      361 gtcaacagta tgacagtgac ccgtacagtt ttggccaggg gaccagagtg gagatccaac
      421 gag
//
LOCUS       KCVT01005475             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23155:12875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005475
VERSION     KCVT01005475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23155:12875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..238
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83000.1"
                     /translation="CMQDIQLPLTF"
     J_segment       239..275
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>278
                     /gene="IGKC"
BASE COUNT           63 a           65 c           81 g           69 t
ORIGIN      
        1 acatgggagg tctagtcaga gcctcctgca tagtaatgga tacacctatt tgttttggta
       61 cctgcagagg ccaggccagt ctccacaact tctggtctat ttgggttcca accgggcctc
      121 tggagtccca gacaggttca gtggcagtgg gtcaggcact gatttcacac tgcaaatcag
      181 ccgggtggag gctgaggatg ttggggttta ttactgcatg caagatatac agcttcctct
      241 cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01005476             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21605:10534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005476
VERSION     KCVT01005476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21605:10534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83001.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          117 g          109 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacagtctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005477             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17933:18331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005477
VERSION     KCVT01005477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17933:18331"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83002.1"
                     /translation="CQQDFDWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          128 c          117 g           89 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc
      241 tcccaagctc ctcctctatg gtgcatccac cagggccacc ggcatcccag acaggttcag
      301 tgccagtggg tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt
      361 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01005478             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19133:20319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005478
VERSION     KCVT01005478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19133:20319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83003.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          119 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggtgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggactgg tacctgcaga agccgggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagact ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005479             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10742:15868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005479
VERSION     KCVT01005479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10742:15868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83004.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          109 a          118 c          106 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca acagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaga tcagacgag
//
LOCUS       KCVT01005480             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10568:11652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005480
VERSION     KCVT01005480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10568:11652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83005.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgcgg acattgtgat gacccagact
      121 ccactctccc tggccgtcac tcttggagag ccggcctcca tttcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 atcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005481             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14155:15470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005481
VERSION     KCVT01005481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14155:15470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..316
                     /note="immunoglobulin light chain variable region"
     V_region        8..316
     V_segment       8..270
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83006.1"
                     /translation="CQQYYSFPITF"
     J_segment       284..316
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        317..>322
                     /gene="IGKC"
BASE COUNT           79 a           82 c           82 g           79 t
ORIGIN      
        1 acatgggtga cccagtctcc atcctccctg tctgcatctg tgggagacaa agtcaccatc
       61 acttgccgag ccagtcaggg tattaacacc tggttaattt ggtatcagca gaaaccaggg
      121 aaagccccta aggccctgat ctataaggca tccagtttgc aaggtggggt cccttccagg
      181 ttcagcggca gtggatctgg ggcagacttc actctcacca tcaccaacct gcagcctgaa
      241 gattttggaa tttattactg tcaacaatat tatagttttc cgatcacttt cggtgggggg
      301 accaaggtgg agatcaggcg ag
//
LOCUS       KCVT01005482             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18722:10654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005482
VERSION     KCVT01005482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18722:10654"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83007.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccattgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005483             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9029:3251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005483
VERSION     KCVT01005483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9029:3251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83008.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcaccttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01005484             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6530:5039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005484
VERSION     KCVT01005484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6530:5039"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..403
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83009.1"
                     /translation="CLQSKNSPWSF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          101 a          119 c          124 g          100 t
ORIGIN      
        1 acatgggggg gggccctgag gagcagcctc tagttcagct ctcagaaatg gggtcctggg
       61 ctcctttcct gtggatcctc ctgctctgtg ctccaggctg cagtggggac attgtgctga
      121 cccagtctcc agcctctttg gccgtgtctc cagggcagag ggccaccatc acctgcagag
      181 ccagtgagag tgtcagtgcc tttggaataa gcctcattca ctggtatcaa cagaaaccag
      241 gacaacctcc taaactcctg atttaccaag caatcaataa ggagactggg gtcccagcca
      301 ggttcagcgg cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaacctg
      361 acgatggtgc agattattac tgtctgcaga gtaagaattc tccgtggtcg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005485             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:8474:15076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005485
VERSION     KCVT01005485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:8474:15076"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83010.1"
                     /translation="CMQPLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggaa ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaacctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005486             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15861:18566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005486
VERSION     KCVT01005486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15861:18566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..285
                     /note="immunoglobulin light chain variable region"
     V_region        5..285
     V_segment       5..247
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83011.1"
                     /translation="CLQGYITPYSF"
     J_segment       248..285
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           77 a           66 c           76 g           69 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gccgggcaag tcaggacatt agcgattttt
       61 taagttggta tcagcagaaa ccaggaaaac ctcctaagcg cctgatttat gctgcatcca
      121 gtttgcaaag tggggtcccg tcaaggttca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcggctta ttattgtcta cagggttata
      241 ttaccccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01005487             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16037:9966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005487
VERSION     KCVT01005487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16037:9966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83012.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005488             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22671:8951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005488
VERSION     KCVT01005488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22671:8951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83013.1"
                     /translation="CQQYNSDPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          110 a          118 c          110 g           90 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcaggacatt accagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatgtat tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtataaca gtgaccctcc gacgttcggc caagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005489             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22443:13932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005489
VERSION     KCVT01005489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22443:13932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83014.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          125 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag gggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01005490             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6275:6697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005490
VERSION     KCVT01005490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6275:6697"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83015.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcaacagaa gccagggaaa gccccgaagc ccttgatcta
      241 ttatgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005491             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22334:18665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005491
VERSION     KCVT01005491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22334:18665"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..431
                     /note="immunoglobulin light chain variable region"
     V_region        113..431
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83016.1"
                     /translation="CQQYFSSPFTF"
     J_segment       397..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>437
                     /gene="IGKC"
BASE COUNT           97 a          128 c          115 g           97 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaacg gacaagttat
      121 attgactcag tctccagcca gcctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggactg agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgctgtgtat tactgtcagc agtattttag ctccccattc actttcggcc ccgggaccaa
      421 actggatatc agacgag
//
LOCUS       KCVT01005492             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:7452:7462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005492
VERSION     KCVT01005492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7452:7462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83017.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          125 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005493             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24803:12142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005493
VERSION     KCVT01005493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24803:12142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83018.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg acatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01005494             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19106:16866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005494
VERSION     KCVT01005494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19106:16866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83019.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtatacatca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctcatcgg gactctgggg tcccagacag attcagcggc
      301 agtgggacag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01005495             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9683:5102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005495
VERSION     KCVT01005495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9683:5102"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83020.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcgg aagccaggcc
      241 agtctccaca gctcctcatt tatgaggttt ccaaccgggc ctctggagtc ccagagaggt
      301 tcagtggcag tgggtcagac actgaattca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgt atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatgaaacga g
//
LOCUS       KCVT01005496             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:27894:11088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005496
VERSION     KCVT01005496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:27894:11088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..418
                     /note="immunoglobulin light chain variable region"
     V_region        98..418
     V_segment       98..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83021.1"
                     /translation="CLQYKSYPFTF"
     J_segment       382..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>422
                     /gene="IGKC"
BASE COUNT          106 a          114 c          100 g          102 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcttg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg caggagacac tgtcaccatc acttgccggg caagtcagaa
      181 tattggcacc tatttaaatt ggtttcagca gaaaccaggg aaagccccta agctcctgat
      241 ctatgctgca tctagtctgg aaagtggggt cccatcaagg ttcagcggca gtggatttgg
      301 gacagaattc actctcatca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tctacagtat aaaagttatc cattcacctt cggccccggg accaaactgg atatcaaagg
      421 ag
//
LOCUS       KCVT01005497             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10081:9847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005497
VERSION     KCVT01005497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10081:9847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83022.1"
                     /translation="CQQHDNSPPTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggga gtctcagaca gggcacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctcctt
      121 cctccctgtc tgcatctata ggcgacagag tcaccatcac ttgcagagcc agtcagggta
      181 ttagcgactg gttggcctgg tatcaacaga aaccagggaa agcccctaaa ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc aggctgaaga tttcgcaaca tatttctgtc
      361 aacagcatga taattcccct cccactttcg gtggagggac taaggtggag atcaaacgag
//
LOCUS       KCVT01005498             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22858:14603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005498
VERSION     KCVT01005498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22858:14603"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..256
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <234..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83023.1"
                     /translation="CMQPLEFPWTF"
     J_segment       257..294
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>297
                     /gene="IGKC"
BASE COUNT           73 a           67 c           87 g           70 t
ORIGIN      
        1 acatgggggc ctccatctcc tgcaggtcta gtcagagcct cttggatagt gaggatggaa
       61 acacttattt ggaatggtac ctgcagaagc caggccagtc tccacagctc ttgatttatg
      121 aggtttccaa ccgggcctct ggagtcccag acaggttcag tggcagtggg tcagacactg
      181 atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat tactgcatgc
      241 aacctctaga gtttccgtgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01005499             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22772:17482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005499
VERSION     KCVT01005499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22772:17482"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83024.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct gggagagccg gcctccatct cctgccggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggc acctgcagag gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc tatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggtattt attactgcat gcaagctcta gagtttcctt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005500             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19220:4375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005500
VERSION     KCVT01005500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19220:4375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83025.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct acatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01005501             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11863:19925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005501
VERSION     KCVT01005501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11863:19925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83026.1"
                     /translation="CQQYNSDLFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tttgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccatt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gacctgttca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005502             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22078:15728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005502
VERSION     KCVT01005502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22078:15728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..444
                     /note="immunoglobulin light chain variable region"
     V_region        102..444
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83027.1"
                     /translation="CMQALEFPPFTF"
     J_segment       407..444
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT           98 a          125 c          117 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattat tgcatgcaag ctctagagtt tcctccattc actttcggcc
      421 ccgggaccaa actggagatc aaacgag
//
LOCUS       KCVT01005503             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15513:15082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005503
VERSION     KCVT01005503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15513:15082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83028.1"
                     /translation="CMQALGFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagggtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005504             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14687:16931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005504
VERSION     KCVT01005504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14687:16931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83029.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          117 c          124 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc agcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctgttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aattcaaacg ag
//
LOCUS       KCVT01005505             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17455:16716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005505
VERSION     KCVT01005505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17455:16716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..440
                     /note="immunoglobulin light chain variable region"
     V_region        104..440
     V_segment       104..403
                     /gene="IGKV2-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83030.1"
                     /translation="CMQALQTPRTF"
     J_segment       405..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          104 a          118 c          118 g          103 t
ORIGIN      
        1 acatggggag acagatcaga actgctcagt tcaccttctc aagatgaagt tccatgctca
       61 gctcctggga ctgttaatgc tctgggtctc tgaatccagt ggggatattg tgatgaccca
      121 gactccactc tccctgcccg tgacccctgg ggagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ctacatagta atggaaatac ctatttgtat tggtacctgc agaagccagg
      241 gcagcctcca cggctcctaa tctatagagt ttccacccgg ttctctggag tgccagacag
      301 gttcagtggc agtggatcag gcacagactt cacactgaaa atcagccggg tggaggctga
      361 ggatgtcggg gtttattact gcatgcaagc tttacagact cctcggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005506             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17695:21084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005506
VERSION     KCVT01005506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17695:21084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83031.1"
                     /translation="CLQFKSYPNSF"
     J_segment       381..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          105 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccactc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa agttacccga acagttttgg ccaggggacc aaagtggaga tcaagcgag
//
LOCUS       KCVT01005507             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16929:13528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005507
VERSION     KCVT01005507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16929:13528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83032.1"
                     /translation="CQQYNNSPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           98 t
ORIGIN      
        1 acatggggga gtcagtccca ttcaggacac agcatggaca tgagggtccc cactcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtctgcatc tgtgggagac agagtcacca tcacttgccg ggcgagtcag
      181 gacattgaca gttatttgag ttggtatcag cagaaaccag ggaaagcccc taagcccctg
      241 atctattata catccagttt gcaatcaggg gtaccgtcaa ggttcagtgg aagtcgatct
      301 gggacagatt atagtctcac catcagcagt ctgcagcctg aagattttgc aacatattac
      361 tgtcaacagt ataataattc cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005508             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10564:14487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005508
VERSION     KCVT01005508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10564:14487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83033.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          118 c          103 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcaccagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01005509             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23712:19044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005509
VERSION     KCVT01005509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23712:19044"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83034.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005510             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13435:8457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005510
VERSION     KCVT01005510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13435:8457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83035.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          118 c          108 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagccac
      181 gatataaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct
      301 gggacagatt tcactctcag catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005511             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13699:18220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005511
VERSION     KCVT01005511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13699:18220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83036.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          117 c          111 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaagca ggtaaagccc cgaagcccct
      241 gatctattac gcatcgaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005512             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9308:13385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005512
VERSION     KCVT01005512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9308:13385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83037.1"
                     /translation="CQQYNSLPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          108 c          108 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaga tatttaaatt ggtatcagca gaaaccgggg aaagccccta agttcctgat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattattg
      361 tcaacagtat aatagtttac cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005513             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9686:4810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005513
VERSION     KCVT01005513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9686:4810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83038.1"
                     /translation="CGQGTHLPWTF"
     J_segment       269..306
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           82 a           79 c           87 g           61 t
ORIGIN      
        1 acatgggcac ccctggacag ccggcctcca tctcctgcag gtctagtcaa agccttgtac
       61 acatcaatgg aaacacatac ttgagttggt atcagcagaa cccaggccaa cctccaaggc
      121 gcctaattta tgaggtttct aaccgggact ctggggtccc agacagattc agcggcagtg
      181 gggcagggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttgggcttt
      241 attactgcgg gcaaggtaca caccttccgt ggacgttcgg ccaagggacc aaggtggaaa
      301 tcaaacgag
//
LOCUS       KCVT01005514             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5013:10801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005514
VERSION     KCVT01005514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5013:10801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83039.1"
                     /translation="CQQGYSPPCSF"
     J_segment       387..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          115 c          118 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattggca gctggttagc ctggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctataagg cgtccagttt ggcaagtggg gtcccatcta ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagcctg aagattttgc aatttattat
      361 tgtcaacagg gttacagtcc cccgtgcagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005515             254 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12000:2292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005515
VERSION     KCVT01005515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 254)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12000:2292"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..251
                     /note="immunoglobulin light chain variable region"
     V_region        7..251
     V_segment       7..209
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83040.1"
                     /translation="CQQYDSDSLTF"
     J_segment       214..251
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>254
                     /gene="IGKC"
BASE COUNT           67 a           60 c           68 g           59 t
ORIGIN      
        1 atgggctcag gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc
       61 gaagcccttg atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg
      121 cagtggatct gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc
      181 aacttattac tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt
      241 ggagatcaaa cgag
//
LOCUS       KCVT01005516             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21713:8124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005516
VERSION     KCVT01005516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21713:8124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83041.1"
                     /translation="CLQFKTFPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          118 c          104 g          101 t
ORIGIN      
        1 acatggggca gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatctc ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctaag ctcctcatct
      241 atgctgcatc cactttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagacttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 tacagtttaa aactttcccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01005517             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:6478:13917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005517
VERSION     KCVT01005517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:6478:13917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83042.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005518             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26838:13962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005518
VERSION     KCVT01005518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26838:13962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83043.1"
                     /translation="CQQYNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          118 c          106 g           93 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aataattatt ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005519             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14183:8807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005519
VERSION     KCVT01005519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14183:8807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83044.1"
                     /translation="CQQYNSFPFIF"
     J_segment       385..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          112 c          103 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 ttacaattat ttaaattggt atcagcagaa accggggaaa gcccctaaac tgctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctggaac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaacct attactgtca
      361 gcagtataat agtttcccgt tcatttttgg ccaggggacc acagtggaca tcaaacgag
//
LOCUS       KCVT01005520             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14709:5822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005520
VERSION     KCVT01005520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14709:5822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..303
                     /note="immunoglobulin light chain variable region"
     V_region        20..303
     V_segment       20..265
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <243..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83045.1"
                     /translation="CMQALDFPWTF"
     J_segment       266..303
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>306
                     /gene="IGKC"
BASE COUNT           75 a           68 c           91 g           72 t
ORIGIN      
        1 acatggggac tgatcacgac tccatctcct gtaggtctag tcagagcctc ttggatagtg
       61 aggatggaaa cacctatttg gaatggtacc tgcagaagcc agggcagtct ccacaactct
      121 tgatttatga ggtttccgac cgggcctctg gagtcccaga caggttcagt ggcagtgggt
      181 cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggggtttatt
      241 actgcatgca agctctggac tttccgtgga cgttcggcca agggaccaag gtggaagtca
      301 aacgag
//
LOCUS       KCVT01005521             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18232:9446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005521
VERSION     KCVT01005521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18232:9446"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..375
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <353..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83046.1"
                     /translation="CLQFKTFPYSF"
     J_segment       376..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT           96 a          117 c          102 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag acactgtcac catctcttgc cgggcaagtc agggtattag
      181 cagttcttta agttggtttc agcagaaacc agggaaagcc cctaagctcc tcatctatgc
      241 tgcatccact ttggccggtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga
      301 cttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt actgtctaca
      361 gtttaaaact ttcccgtaca gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01005522             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21862:12541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005522
VERSION     KCVT01005522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21862:12541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..429
                     /note="immunoglobulin light chain variable region"
     V_region        94..429
     V_segment       94..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83047.1"
                     /translation="CGQGTHLPWTF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          100 a          120 c          116 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcat ggacagattt cacactgaaa atcagcagag tggaggctga gatgttgggc
      361 tttattactg cgggcaaggt acacaccttc cgtggacgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01005523             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11225:10185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005523
VERSION     KCVT01005523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11225:10185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83048.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga caaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca acagaaacct gggcaggctc ccagactcct
      241 catctttggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005524             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12305:15806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005524
VERSION     KCVT01005524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12305:15806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83049.1"
                     /translation="CQQYNSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          111 c          114 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatcg gcaggagaca gagtcaccat taattgtcgg gcgagtcagg
      181 acattagtag ttatttagcg tggtatcggc agaggccagg gaaagccccg gagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgga acttattact
      361 gtcaacagta taacagtgac tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005525             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9357:20307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005525
VERSION     KCVT01005525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9357:20307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83050.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          101 a          123 c          112 g           85 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcgtagcctg gtaccagcaa aaacctgggc aggctcccag actcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01005526             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18183:15226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005526
VERSION     KCVT01005526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18183:15226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83051.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          125 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005527             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8849:18417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005527
VERSION     KCVT01005527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8849:18417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83052.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005528             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16649:4029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005528
VERSION     KCVT01005528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16649:4029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83053.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctttgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005529             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13194:15252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005529
VERSION     KCVT01005529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13194:15252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83054.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          111 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagg cattgatcta
      241 ttacgcgtcc actttggaaa atggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc agggtggaga tcaaacgag
//
LOCUS       KCVT01005530             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13469:3519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005530
VERSION     KCVT01005530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13469:3519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83055.1"
                     /translation="CQHSYDTPYTF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          116 c          110 g           96 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagtg tcaccatcac ttgcagggca agtgcgagcg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggag agtccctgag ctcctgatct
      241 atgctgcatc gtctttgcaa ggtggggtcc catcaaggtt cagcggcggt ggatctggga
      301 cagatttcac cctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtta tgataccccc tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01005531             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12772:11704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005531
VERSION     KCVT01005531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12772:11704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83056.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          120 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005532             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7134:8205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005532
VERSION     KCVT01005532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7134:8205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83057.1"
                     /translation="CQQYNSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          111 c          109 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtca attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005533             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18308:3091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005533
VERSION     KCVT01005533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18308:3091"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83058.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          115 c          101 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01005534             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8715:11014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005534
VERSION     KCVT01005534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8715:11014"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83059.1"
                     /translation="CQQGDGLPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          112 c          107 g          102 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcagttgccg ggcaagtcag
      181 gccattagca gttatttata ttggtatcag cagaaaccgg ggaaaccccc taaacttctg
      241 atttataagg catatctttt ggaagatggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac tatcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagg gtgatggttt accattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01005535             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6078:8184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005535
VERSION     KCVT01005535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6078:8184"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83060.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tgctgaggat ggaaacacct acttggaatg gtatttacag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaagctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005536             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18253:15893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005536
VERSION     KCVT01005536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18253:15893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83061.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgt agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005537             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13836:16977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005537
VERSION     KCVT01005537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13836:16977"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..247
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83062.1"
                     /translation="CQQNSNWPLTF"
     J_segment       248..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           72 a           76 c           82 g           57 t
ORIGIN      
        1 acatggggga gaaagagcca ccctctcctg cagggccagt cagagtgtca gcagcagtgt
       61 agcctggtac cagcaaaaac ctgggcaggc tcccagactc ctcatctatg gtgcatccaa
      121 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcactct
      181 caccatcagc agcctggagc ctgaagatgt tgcactttat tattgtcagc agaatagtaa
      241 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005538             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19531:12470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005538
VERSION     KCVT01005538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19531:12470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83063.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          122 c          118 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatgtatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01005539             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13100:20243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005539
VERSION     KCVT01005539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13100:20243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83064.1"
                     /translation="CQQYDSDLFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          113 c          111 g           95 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatttgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgacct gttcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01005540             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18478:9470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005540
VERSION     KCVT01005540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18478:9470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..390
                     /note="immunoglobulin light chain variable region"
     V_region        69..390
     V_segment       69..343
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <330..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83065.1"
                     /translation="CQQHNGYPPTF"
     J_segment       356..390
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>393
                     /gene="IGKC"
BASE COUNT           96 a          112 c           99 g           86 t
ORIGIN      
        1 acatgggcat gagggtcccc gctcagctcc tggggctcct gctgctctgg ctcccaggtg
       61 ccagatgtga catccagatg acccagtctc catcctccct gtctgcatct gtaggagaca
      121 cagtcaccat cacttgtcgg gcaagtcagg gcattaccaa tgatttagcc tggtatcagc
      181 agaaaccagg gaaagccccg aagcccctga tctattacgc atccaatttg gaaagtgggg
      241 tcccatcaag gttcagcggc agtggatctg ggacagattt cactctcacc atcagcagcc
      301 tgcagcctga agattttgca acttattatt gtcaacagca taatggatac cctccgacgt
      361 tcggccaagg gaccagggtg gaaatcaaac gag
//
LOCUS       KCVT01005541             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15970:9344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005541
VERSION     KCVT01005541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15970:9344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83066.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          124 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttgttactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaagctgga aatcaaacga g
//
LOCUS       KCVT01005542             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:27044:10101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005542
VERSION     KCVT01005542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27044:10101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83067.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagcc
      181 agagtgttgg cagcacctta acctggtacc accagaagcc tgggcaggct cccaagctcc
      241 tcatctatgg tccttccatc cgggccagcg gcatcccaga caggtttagt ggcagtgggt
      301 ctggaacaga atttactctc accatcagca gcctggagac tgaagatgtt ggagtttatt
      361 actgtcagca ggattatcac tggcctccga cgttcggcca agggaccaag gtggaattca
      421 aacgag
//
LOCUS       KCVT01005543             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20701:12171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005543
VERSION     KCVT01005543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20701:12171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83068.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          118 c          101 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaacccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacaata taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01005544             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10060:9708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005544
VERSION     KCVT01005544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10060:9708"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83069.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005545             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:27789:14823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005545
VERSION     KCVT01005545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:27789:14823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83070.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcgcc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005546             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12740:16504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005546
VERSION     KCVT01005546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12740:16504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83071.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          123 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atctggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaagcac tggagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005547             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20419:7622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005547
VERSION     KCVT01005547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20419:7622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83072.1"
                     /translation="CQHSYGTPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          114 c          107 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtag gacaagtcag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taggctcctg
      241 atctatgctg cgtccaattt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactttcac catcaccagc ctgcaacctg aagatgttgc aacttattac
      361 tgtcagcata gttatggtac cccgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005548             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16624:11621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005548
VERSION     KCVT01005548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16624:11621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..390
                     /note="immunoglobulin light chain variable region"
     V_region        127..390
     V_segment       127..348
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <330..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83073.1"
                     /translation="CQQYDSDSLTF"
     J_segment       353..390
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>393
                     /gene="IGKC"
BASE COUNT           97 a          109 c          101 g           86 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagcctc
      121 catcctccat cacttgtcgg gcgactcagg acattcgcag ttatttagcg tggtatcagc
      181 agaaaccagg gaaagccccg aagcccttga tctattacgc gtccactttg gaaagtgggg
      241 tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc atcagcagcc
      301 tgcagcctga agattttgca acttattact gtcaacagta tgacagtgat tcgctcactt
      361 tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005549             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19201:9670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005549
VERSION     KCVT01005549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19201:9670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83074.1"
                     /translation="CQQYNSDPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          118 c          104 g           94 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaaccc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca atataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      421 aacgag
//
LOCUS       KCVT01005550             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13480:9850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005550
VERSION     KCVT01005550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13480:9850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..242
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83075.1"
                     /translation="CQQYDSDSLTF"
     J_segment       247..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           75 a           69 c           76 g           64 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg tcgggcgact caggacattc gcagttattt
       61 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac
      121 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      241 tgattcgctc actttcggtg gagggaccaa ggtggagatc aaac
//
LOCUS       KCVT01005551             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:26566:19813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005551
VERSION     KCVT01005551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26566:19813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83076.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgccctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005552             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6428:12611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005552
VERSION     KCVT01005552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6428:12611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83077.1"
                     /translation="CQQGYGLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          118 c          105 g           93 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagcat ggacatgagg gcccccactc agctcctggg
       61 gttcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctatag gagacagagt caccatcact tgccaggcga atcaggacat
      181 taacaatatt ttagcctggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 tgaggcatcc actttacaaa gtggggtccc atcacggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 gcaaggttat ggtctcccgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01005553             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21975:15329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005553
VERSION     KCVT01005553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21975:15329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83078.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          119 c          127 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ctctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005554             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:27989:8129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005554
VERSION     KCVT01005554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27989:8129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..375
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83079.1"
                     /translation="CLQYKSYPFTF"
     J_segment       376..413
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          105 a          112 c           96 g          103 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggttat
      181 tatcaattat ttaaattggt ttcagaaacc agggaaagcc cctaagctcc tgatttatgc
      241 tgcatccaga ttggaaagtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga
      301 tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt actgtctaca
      361 gtataaaagt tacccattca ctttcggccc cgggaccaaa ctggatatca aacgag
//
LOCUS       KCVT01005555             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9492:16920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005555
VERSION     KCVT01005555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9492:16920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83080.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          106 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gtccctgagc tcctgatcta
      241 tgctgcatcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005556             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12815:9264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005556
VERSION     KCVT01005556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12815:9264"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83081.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc tagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccagggca
      241 gtctccacaa ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct ggactttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01005557             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19211:20570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005557
VERSION     KCVT01005557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19211:20570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..446
                     /note="immunoglobulin light chain variable region"
     V_region        128..446
     V_segment       128..411
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <389..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83082.1"
                     /translation="CQHYFSSPFTF"
     J_segment       412..446
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>452
                     /gene="IGKC"
BASE COUNT          102 a          135 c          116 g           99 t
ORIGIN      
        1 acatggggat caatgcctgg gtcagagctc tggagaagag ctgctcagtt aggacccaga
       61 gagaaccatg gaaatcccag ctcagcttct cttcctcctg ctactgtggc tcccaggtac
      121 caccggacaa gttatattga ctcagtctcc agccaccctg tctttgtctc caggggaaag
      181 agccaccctc tcctgcaggg ccagtcagag tgttggcagc agcttagcct ggtaccagca
      241 gaaacctggg caggccccca ggctcctcat ctatggtgca tccaacaggg ccactggcat
      301 cccagacagg ttcagtggca gtgggtctgg gacagagttc actctcacca tcagcagcct
      361 ggagcctgaa gattttgcag tgtattactg tcagcactat tttagctccc cattcacttt
      421 cggccccggg accaaactgg atatcagacg ag
//
LOCUS       KCVT01005558             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16901:20130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005558
VERSION     KCVT01005558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16901:20130"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83083.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggtcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005559             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20092:13759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005559
VERSION     KCVT01005559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20092:13759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83084.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c          101 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgatgat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01005560             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:2730:14767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005560
VERSION     KCVT01005560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:2730:14767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83085.1"
                     /translation="CQQGYNTPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          114 c          117 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 gatattagca gctggttagc ctggtatcag ctgaagccgg ggaaagcccc taaactcttg
      241 atctataagg cgtccagttt ggcaagaggg gtcccatcga ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagtagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagg gttacaatac cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005561             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19202:12855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005561
VERSION     KCVT01005561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19202:12855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83086.1"
                     /translation="CQQYNSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          114 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005562             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16489:4836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005562
VERSION     KCVT01005562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16489:4836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83087.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgccga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagttccct tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005563             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10392:9591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005563
VERSION     KCVT01005563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10392:9591"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83088.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005564             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:8540:15810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005564
VERSION     KCVT01005564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8540:15810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83089.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggtgaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaactagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005565             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19636:11317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005565
VERSION     KCVT01005565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19636:11317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83090.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          109 c          109 g           99 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attgagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cgttaacgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta agcccctgat
      241 cttttatgca aaccgtttgg aacgtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa gttattattg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005566             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18116:17833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005566
VERSION     KCVT01005566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18116:17833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..273
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83091.1"
                     /translation="CQQYHSFPLTF"
     J_segment       274..307
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>313
                     /gene="IGKC"
BASE COUNT           82 a           76 c           75 g           80 t
ORIGIN      
        1 acatgggctc catcctccct gtctgcttct gtaggggaca gagtcaccat cacttgccgg
       61 gcaagtcagg acattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct
      121 aagctcctga tgtattattc aaaccgtttg gaaagtgggg tcccatcaaa gttcagcggc
      181 ggtggatctg ggacagaatt cactctcacc atcatcaacc tgcaacctga agattttgca
      241 acttattact gtcaacagta tcatagtttt cctctcactt tcggcggagg gaccaaggtg
      301 gagatcagac gag
//
LOCUS       KCVT01005567             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13254:2886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005567
VERSION     KCVT01005567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13254:2886"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83092.1"
                     /translation="CLQFKAYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          117 c          106 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaacc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcagttt attactgtct
      361 gcagtttaaa gcctacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005568             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13672:17652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005568
VERSION     KCVT01005568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13672:17652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83093.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          117 c          105 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005569             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9998:9129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005569
VERSION     KCVT01005569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9998:9129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83094.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          115 c          111 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cagtttggaa agtggggtcc catcaaggtt cagcggcggt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagac atcaaacgag
//
LOCUS       KCVT01005570             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20341:3730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005570
VERSION     KCVT01005570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20341:3730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..362
                     /note="immunoglobulin light chain variable region"
     V_region        85..362
     V_segment       85..320
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <302..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83095.1"
                     /translation="CQQYDSDSLTF"
     J_segment       325..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           91 a           96 c           98 g           80 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggaga cagagtcacc atcacttgtc gggcgactca
      121 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      181 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      241 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      301 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01005571             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25122:10142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005571
VERSION     KCVT01005571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25122:10142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83096.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccatgcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01005572             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9458:20899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005572
VERSION     KCVT01005572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9458:20899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83097.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggcaaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005573             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:14754:15422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005573
VERSION     KCVT01005573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14754:15422"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83098.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          104 a          125 c          113 g           85 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcaacagctt agcctggtac caacaaaaac ctgggcagcc tcccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag aggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01005574             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:27716:13105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005574
VERSION     KCVT01005574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:27716:13105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83099.1"
                     /translation="CQQHDNMPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          115 c          114 g           87 t
ORIGIN      
        1 acatggggag tcagtcgcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattagcaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatagggc atggaatctg gaaacagggg tcccatcaag gttcagtgga agtggatccg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgataatatg ccgctcactt tcggtggagg gaccaaggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01005575             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:23284:14357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005575
VERSION     KCVT01005575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:23284:14357"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83100.1"
                     /translation="CQQYDSDPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01005576             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9673:13962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005576
VERSION     KCVT01005576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9673:13962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83101.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           93 a          122 c          123 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtcg gccactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005577             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18215:15094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005577
VERSION     KCVT01005577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18215:15094"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83102.1"
                     /translation="CLQYKSYPFTF"
     J_segment       388..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          108 a          116 c          101 g          103 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgcagg agacactgtc accatcactt gccgggcaag
      181 tcagggtatt agtacctatt taaattggtt tcagcagaaa ccagggaaag cccctaacct
      241 cctgatctat gctgcatcta gtctggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atttgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta
      361 ttattgtcta cagtataaaa gttatccatt cactttcggc cccgggacca aactggatat
      421 caaacgag
//
LOCUS       KCVT01005578             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:27534:11112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005578
VERSION     KCVT01005578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:27534:11112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83103.1"
                     /translation="CQQYFSSPFTF"
     J_segment       387..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>427
                     /gene="IGKC"
BASE COUNT           95 a          126 c          111 g           95 t
ORIGIN      
        1 acatgggggg aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat attgactcag
      121 tctccagcca cgctgtcttt gtctccaggg gaaagaggca ccctctcctg caggaccagt
      181 cagagtcttg gtagcagctt agcctggtac cagcagaaac ctgggcaggc cccccggctc
      241 ctcatctatg gtgtatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt tgcagtgtat
      361 tactgtcagc agtattttag ctccccattc actttcggcc ccgggaccaa actggatatc
      421 agacgag
//
LOCUS       KCVT01005579             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16696:13313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005579
VERSION     KCVT01005579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16696:13313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83104.1"
                     /translation="CMQYIHMPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctgggt ccagtgggga tattgtgatg acccagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggattg gtacctgcag aagccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcaatggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 attttggggt ttattactgc atgcaatata tacacatgcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005580             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12653:8428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005580
VERSION     KCVT01005580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12653:8428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83105.1"
                     /translation="CQQDYSWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          120 c          118 g           87 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttgtcttcc tcctgctact ctggatccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcatctt agcctggtac caccagaaac ctgggcaggc tcccaagtcc
      241 ctcatctatg gtgcaaccag tagggccacc ggcatcccag acaggttcag tggcagtggg
      301 tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt tggcgtttat
      361 tactgtcagc aggattatag ctggccactc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01005581             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:8487:10371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005581
VERSION     KCVT01005581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8487:10371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83106.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattattttg acccagactc
      121 cactctccct gcccgtcatc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01005582             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12513:11800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005582
VERSION     KCVT01005582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12513:11800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83107.1"
                     /translation="CQQDFDWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          129 c          116 g           90 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gagagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc
      241 tcccaagctc ctcctctttg gtacatccac cagggccacc ggcatcccag acaggttcag
      301 tgccagtggg tctcgaacag agtttactct caccatcagc agcctggagc ctgaagatgt
      361 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01005583             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:15677:13164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005583
VERSION     KCVT01005583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15677:13164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..320
                     /note="immunoglobulin light chain variable region"
     V_region        121..320
     V_segment       121..282
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <260..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83108.1"
                     /translation="CLQDIQLPLTF"
     J_segment       283..320
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>323
                     /gene="IGKC"
BASE COUNT           67 a           85 c           92 g           79 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattatgat gactcagact
      121 ccactctcca cagctcctga tctatttcgg ttccaaccgg gcctctggag tcccagacag
      181 gttcagtgcc agtgggtcag gcactgattt cacactgaaa atcagccggg tggaggctga
      241 ggatgttggg gtttattact gcttgcaaga tatacaactt ccgctcactt tcggtggagg
      301 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005584             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11068:6571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005584
VERSION     KCVT01005584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11068:6571"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83109.1"
                     /translation="CQQYDSLPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          109 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacattca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg ccgggcaagt
      181 cagggcatta gcaattattt aaattggtat caggagaaac cggggaaagc ccctaagccc
      241 ctgatctatt atacaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtaga
      301 tctgggacag aattcactct caccatcagc agcctgcaac ctgaggattt tgcaacttac
      361 tactgtcaac agtatgattc tttaccgtgg acgttcggcc aagggaccaa ggtggacatc
      421 aaacgag
//
LOCUS       KCVT01005585             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9851:11631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005585
VERSION     KCVT01005585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9851:11631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83110.1"
                     /translation="CLQGYTIPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          115 c          107 g           95 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt cccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg gacaagtcag
      181 ggcattagcg attatttaag ttggtatcag cagaaaccag gaaaagctcc taagcgcctg
      241 atccatgctg tatccagttt ggaaagtggg gccccatcaa ggttcagcgg cagtggatct
      301 gaaacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagg gttatactat cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005586             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:24044:4555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005586
VERSION     KCVT01005586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24044:4555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..414
                     /note="immunoglobulin light chain variable region"
     V_region        94..414
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83111.1"
                     /translation="CLQYKSYPFTF"
     J_segment       378..414
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>418
                     /gene="IGKC"
BASE COUNT          106 a          112 c           99 g          101 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcttgctgc tctggctccc aggtgccaga tgtgacatcc aactgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcaggatatt
      181 agtagttatt taaattggtt tcagcagaaa acagggaagg cccctaagct cctgatctat
      241 gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg atttgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtataaaa gttacccatt cactttcggc cccgggacca aactggacat caaaggag
//
LOCUS       KCVT01005587             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19140:2821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005587
VERSION     KCVT01005587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19140:2821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83112.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005588             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12703:7374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005588
VERSION     KCVT01005588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12703:7374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83113.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005589             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19523:10323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005589
VERSION     KCVT01005589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19523:10323"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83114.1"
                     /translation="CQQYDSDSLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gactcaggac
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01005590             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17017:11715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005590
VERSION     KCVT01005590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17017:11715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83115.1"
                     /translation="FMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattacttc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005591             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11216:18731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005591
VERSION     KCVT01005591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11216:18731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83116.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          119 c          106 g           92 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagtct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagcat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005592             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5801:15290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005592
VERSION     KCVT01005592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5801:15290"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83117.1"
                     /translation="CLQGYIIPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          110 c          112 g           99 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagcc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt ggaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattat
      361 tgtctacagg gttatattat cccgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005593             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5641:3499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005593
VERSION     KCVT01005593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5641:3499"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83118.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcgtttatgg tgcatccacc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005594             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22321:6407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005594
VERSION     KCVT01005594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22321:6407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83119.1"
                     /translation="CQQYNSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          114 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005595             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17542:15444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005595
VERSION     KCVT01005595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17542:15444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83120.1"
                     /translation="CQQGYSYPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          117 c          111 g           95 t
ORIGIN      
        1 acatgggagt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 ctcctccctg tccgcatctg tgggagacgc agtcacgatc acttgccagg cgagtcaagg
      181 cattggcaat aacttaaatt ggtttcagca gaaaccaggg aaagccccta aactcctgat
      241 ctataagaca tccagtttgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagttacc cgtggacgtt cggccaaggg gccaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005596             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20246:7926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005596
VERSION     KCVT01005596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20246:7926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83121.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct acccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005597             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18096:13867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005597
VERSION     KCVT01005597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18096:13867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83122.1"
                     /translation="CQQYDSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatt tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggttct
      301 gggacagaat tcactctcac catcaacagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cctgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005598             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16436:12069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005598
VERSION     KCVT01005598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16436:12069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83123.1"
                     /translation="CQQGYRYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          106 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tgacattaat ttaaattact atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc cgtttgcaaa gtggggttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat cgttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005599             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14102:10470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005599
VERSION     KCVT01005599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14102:10470"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83124.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005600             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11616:20378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005600
VERSION     KCVT01005600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11616:20378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83125.1"
                     /translation="CQQGSPFPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          111 c          107 g           96 t
ORIGIN      
        1 acatggggat gagcaaaact gacaagtcaa ggcaggaaga tgttgtctcc atcacaactc
       61 attgggtttc tgctgctctg ggttccagcc tccaagggtg aaattgtgct gactcagtct
      121 ccagcctttc ggtctgtgac tctaaaggag aaagtcacca tcacctgcca ggccagtcag
      181 agcattggta atagcttaca ctggtaccag cagaaaccgg atcagtctcc aaagctcctc
      241 atcaaatatg cttcccagtc catctcaggg gtcccctcaa ggttcagtgg cagtggatct
      301 gggacagatt tcaccctcac catcaatagc ctggaagctg aagatgctgc gacgtattac
      361 tgtcagcagg gaagtccttt cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005601             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11225:13234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005601
VERSION     KCVT01005601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11225:13234"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83126.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa tttactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005602             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8892:15857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005602
VERSION     KCVT01005602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8892:15857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83127.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          113 a          118 c          107 g           88 t
ORIGIN      
        1 acatgggggg gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 acgatattaa caactggttg gcctggtatc aacagaaacc agggaaagcc cctaaggtcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggtt
      301 ctgggacaga tttcactctc accatcaaca acctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca acatgatgat tcccctcgga ccttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005603             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11983:11756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005603
VERSION     KCVT01005603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11983:11756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83128.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgattcca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005604             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:16183:4730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005604
VERSION     KCVT01005604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16183:4730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83129.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctcccc gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc cctgacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005605             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6406:20795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005605
VERSION     KCVT01005605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6406:20795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83130.1"
                     /translation="CQQYTSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccagc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtgaggacgt
      181 tagtagtcat ttaaattggt atcagcggaa accggggaaa gcccctaagc tcctgatcta
      241 ttttgcaaac cgtttggaaa gaggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca ccagcctgca acctgaggac tttgcaactt atcactgtca
      361 acagtacact agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01005606             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11725:11028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005606
VERSION     KCVT01005606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11725:11028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..331
                     /note="immunoglobulin light chain variable region"
     V_region        131..331
     V_segment       131..293
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83131.1"
                     /translation="CMQALEFPFTF"
     J_segment       294..331
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           73 a           93 c           85 g           83 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga
      181 gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga
      241 gtggaggctg aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcact
      301 ttcggccccg ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01005607             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15741:14431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005607
VERSION     KCVT01005607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15741:14431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83132.1"
                     /translation="CQQYNTLPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          116 c          102 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgagatt cagatgaccc agtctccatc
      121 ctccctgtct gcctctgtcg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcaattat ttaaattggt atcagcagag accggggaaa gcccctaaac tcctgatcta
      241 ttatgcatcc cgtttggaga atggggtccc atcaaagttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gtagcctgca acctgaagat tttgcagctt attactgtca
      361 gcagtataat accttaccat tcactttcgg ccccgggacc aaactggaaa tcaaacgag
//
LOCUS       KCVT01005608             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5546:16573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005608
VERSION     KCVT01005608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5546:16573"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83133.1"
                     /translation="CIQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005609             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23764:8457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005609
VERSION     KCVT01005609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23764:8457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83134.1"
                     /translation="CQQYDDYPWTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          101 a          116 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaagagaca aagtcaccat cacttgccgt gccagtcagg
      181 gtattagtag tcggttagtc tggtatcagc agaaaccagg gaaagcccct aagcccctga
      241 tgtatgctgc ttccagttta cacagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgatgattac ccgtggacgt tcggccaagg gaccaaggtg gaaatcaagc
      421 gag
//
LOCUS       KCVT01005610             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21849:12269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005610
VERSION     KCVT01005610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21849:12269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83135.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          122 c          113 g          102 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctaca tagtaatgga tacacgtatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta ctactgtatg cagagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01005611             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21656:9702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005611
VERSION     KCVT01005611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21656:9702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83136.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt tcaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005612             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20374:13924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005612
VERSION     KCVT01005612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20374:13924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83137.1"
                     /translation="CQHSFRTPYSF"
     J_segment       367..404
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           97 a          112 c          105 g           93 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggc ctctgctcag ctcctagggc tcctgctgct
       61 ctggctccca ggcgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
      121 atctgtagga gacagagtca atgtcacttg cagggctagt gagagcgtta gcaccaaatt
      181 acattggtat cagcagaaac cagggaaagc ccctaagctc ctgatctttg ctgcgtccac
      241 tttgcaaagt ggggtcccat caaggttcag cggcagtgga tctggaacag atttcactct
      301 caccatcagc agcctgcagc ctgaagatgt cgcaactttt tactgtcagc atagttttcg
      361 taccccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01005613             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14361:22325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005613
VERSION     KCVT01005613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14361:22325"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83138.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 caccctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005614             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11021:3900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005614
VERSION     KCVT01005614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11021:3900"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83139.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005615             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17348:5491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005615
VERSION     KCVT01005615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17348:5491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83140.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggggagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacgt atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005616             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8937:12835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005616
VERSION     KCVT01005616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8937:12835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83141.1"
                     /translation="WQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attggcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005617             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5557:11809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005617
VERSION     KCVT01005617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5557:11809"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83142.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005618             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20854:20614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005618
VERSION     KCVT01005618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20854:20614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83143.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc ttagagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttaattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005619             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11819:8270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005619
VERSION     KCVT01005619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11819:8270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83144.1"
                     /translation="CIQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          111 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cttctcctgt aggtctagtc
      181 acagcctctt ggatagtgag gatggaaata tccatttgga ttggtatctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggtttagtgg cagtgggtca gacactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttactac tgcatacaat ctcttgagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005620             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16536:16700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005620
VERSION     KCVT01005620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16536:16700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..246
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83145.1"
                     /translation="CQQGDSYPRTF"
     J_segment       248..283
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           84 a           66 c           75 g           61 t
ORIGIN      
        1 acatggggag acagagtcac catcacttgc cgggcaagtc aggacattag agattattta
       61 aattggtatc agcagcaacc ggggaaagcc cctaaactcc tgatgtatta tgcaaacagt
      121 ctggcaagtg gagtcccatc aaggttcagc ggcagtggat ctgggacaga attcagtctc
      181 accatcagca gcctgcagcc tgaagatttt gcaacttatt actgtcaaca gggtgacagt
      241 tatcctcgga cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01005621             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22862:17360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005621
VERSION     KCVT01005621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22862:17360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..430
                     /note="immunoglobulin light chain variable region"
     V_region        98..430
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83146.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          121 g          101 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtac cagacaggtt
      301 cagtggcagt gggtcagaca ctgctttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 cagggtggaa cccaaacgag
//
LOCUS       KCVT01005622             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23487:16444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005622
VERSION     KCVT01005622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23487:16444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83147.1"
                     /translation="CQQYNSFPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          115 c          106 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacgtgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cacttgaccc agtctccatc
      121 ctccctgtct gcttctctag gagacagagt caccctctct tgccgggcaa gtcagggcgt
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaacc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agttttcctc tcactttcgg cggagggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005623             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17655:6364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005623
VERSION     KCVT01005623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17655:6364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..405
                     /note="immunoglobulin light chain variable region"
     V_region        84..405
     V_segment       84..367
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83148.1"
                     /translation="CQQYDSDPFTF"
     J_segment       370..405
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT          100 a          111 c          106 g           91 t
ORIGIN      
        1 acatgggagg acacagcatg gacatgaggg tccccgctca gctcctagga ctcctgctgc
       61 tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc tccctgtctg
      121 catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt cgcagttatt
      181 tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat tacgcgtcca
      241 ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc
      301 tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa cagtatgaca
      361 gtgacccgtt cactttcggt ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01005624             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14004:9246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005624
VERSION     KCVT01005624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14004:9246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83149.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          114 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggtag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005625             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13076:16889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005625
VERSION     KCVT01005625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13076:16889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83150.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          106 g           90 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagtcagg
      181 gtattaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aaactcctta
      241 tctatagggc atccaattta gaaacagggg tcccatcgag gttcggtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatatttct
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005626             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22901:16086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005626
VERSION     KCVT01005626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22901:16086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83151.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag cttggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tctactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005627             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25722:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005627
VERSION     KCVT01005627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25722:10474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..432
                     /note="immunoglobulin light chain variable region"
     V_region        100..432
     V_segment       100..399
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83152.1"
                     /translation="CMQSTKDPRTF"
     J_segment       401..432
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>439
                     /gene="IGKC"
BASE COUNT           99 a          122 c          114 g          104 t
ORIGIN      
        1 acatggggag atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctggc tccagtgggg atattttgat gacccagact
      121 ccactctcgc tgcccgtcac ccctggagag ccggcctcca tctcctgctg gtctagtcaa
      181 agccttcttc acagtactgg aaacacctat ttgcattggt actaccggaa gccaggccag
      241 tctccacgtc tcctgatcta taaagttccc aatcgggagt ctggggtccc agacaggttc
      301 agtgacagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 gttggtgttt attactgcat gcaaagtaca aaagatcccc ggacgttcgg ccaagggacc
      421 aaggtggaaa tctaacgag
//
LOCUS       KCVT01005628             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17854:17895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005628
VERSION     KCVT01005628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17854:17895"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83153.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005629             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16985:12645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005629
VERSION     KCVT01005629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16985:12645"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83154.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          119 c          104 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccac atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01005630             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20819:7707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005630
VERSION     KCVT01005630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20819:7707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83155.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          116 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct tgagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005631             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:16783:8844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005631
VERSION     KCVT01005631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16783:8844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83156.1"
                     /translation="CMQARDFPFTF"
     J_segment       322..359
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           80 a           96 c          103 g           83 t
ORIGIN      
        1 acatgggggg tccattgggg acattgtgat gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttcg atagtgagga
      121 aggaaacacc tatttggagt ggtacctgca gaggccaggc cagtctccac aggtcttgat
      181 ttatggggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgagaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct cgagactttc cattcacttt cggccccggg accaaactgg acatcaaacg
      361 ag
//
LOCUS       KCVT01005632             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:3814:14465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005632
VERSION     KCVT01005632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3814:14465"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..438
                     /note="immunoglobulin light chain variable region"
     V_region        111..438
     V_segment       111..394
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83157.1"
                     /translation="CQQRNTYPYMCSF"
     J_segment       404..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          104 a          117 c          116 g          104 t
ORIGIN      
        1 acatggggac ttcgtgcagg agttagaccc agtctggacg cagcatggac atcagggtcc
       61 tcgctcagct tctcgggctc ctgctgctct ggctcccagg tgccagatgt gacattcagt
      121 tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc
      181 gggcaagtca ggacattagc agttatttag cctggtatca gcagaaacca gggaaagccc
      241 ctaggctcct gatctataag gcgtccagtt tgcaaagtgg ggtcccatca aggttcagcg
      301 gcagtggatc tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg
      361 cagtttatta ctgtcaacag cgtaatactt acccgtacat gtgcagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01005633             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21670:19271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005633
VERSION     KCVT01005633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21670:19271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..377
                     /note="immunoglobulin light chain variable region"
     V_region        112..377
     V_segment       112..347
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83158.1"
                     /translation="CLQGDSTPFTF"
     J_segment       354..377
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>388
                     /gene="IGKC"
BASE COUNT           94 a          104 c          104 g           86 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcactt gccgggcaag tcaggacatt agcgattatt taagttggta tcagcagaaa
      181 ccgggaaaag ctcctaagcg cctaatctat gctgcatcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gagttcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcgactta ttactgtcta cagggtgata gtaccccgtt cacttttggc
      361 caggggacca aagtggacgt caaacgag
//
LOCUS       KCVT01005634             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18210:5739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005634
VERSION     KCVT01005634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18210:5739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83159.1"
                     /translation="CQQYDKLPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          118 c           99 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggccat
      181 tagttatcat ttatattggt atcagcagaa accggggaaa gcccctacac tcctaatcta
      241 ttatggaaac cgtttgcaaa gaggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attcctgtca
      361 acagtatgat aagttaccat tcactttcgg ccccgggacc aaactggaca tcaaacgag
//
LOCUS       KCVT01005635             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:12453:14467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005635
VERSION     KCVT01005635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12453:14467"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83160.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          126 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cgtagtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgggg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005636             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19991:11992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005636
VERSION     KCVT01005636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19991:11992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83161.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          123 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgccg gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggta tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005637             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16801:10564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005637
VERSION     KCVT01005637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16801:10564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83162.1"
                     /translation="CQQHDNSPPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           93 t
ORIGIN      
        1 acatgggggt cagtctcaga cagggcacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 ttcctccctg tctgcatcta taggcgacag agtcaccatc acttgcagag ccagtcaggg
      181 tattagcgac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aactcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcaggctgaa gatttcgcaa catatttctg
      361 tcaacagcat gataattccc ctcccacttt cggtggaggg actaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005638             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19406:19134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005638
VERSION     KCVT01005638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19406:19134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83163.1"
                     /translation="CMQALEFPYSF"
     J_segment       404..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctattgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcat ggatagtggg gatgtaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acatctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacggatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtacagt tttggccagg
      421 ggaccagagt ggagatcaaa cgag
//
LOCUS       KCVT01005639             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14667:4839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005639
VERSION     KCVT01005639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14667:4839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83164.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005640             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13501:10240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005640
VERSION     KCVT01005640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13501:10240"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..358
                     /note="immunoglobulin light chain variable region"
     V_region        45..358
     V_segment       45..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <298..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83165.1"
                     /translation="CMQALEFPWTF"
     J_segment       322..358
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>361
                     /gene="IGKC"
BASE COUNT           83 a           93 c          101 g           84 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccgtcacc
       61 ctgggagagc cggcctccat ctcctgccgg tctagtcaga gcctcttgga tagtgaggat
      121 ggaaacacct atttggaatg gcacctgcag aggccaggcc agtctccaca gctcttgatt
      181 tatgaggttt cctatcgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac
      241 actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggtat ttattactgc
      301 atgcaagctc tagagtttcc ttggacgttc ggccaaggga ccaaggtgga aatcaaacga
      361 g
//
LOCUS       KCVT01005641             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:10289:8286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005641
VERSION     KCVT01005641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10289:8286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83166.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc ctaggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01005642             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11269:9363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005642
VERSION     KCVT01005642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11269:9363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83167.1"
                     /translation="CMQALEFPFTF"
     J_segment       322..359
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           81 a           95 c          100 g           86 t
ORIGIN      
        1 acatggggga tccagtgggg acattgtgat gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga
      121 tggaaacacc tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat
      181 ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acacttataa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct ctagagtttc cattcacctt cggccccggg accagactgg atgtcaaacg
      361 ag
//
LOCUS       KCVT01005643             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12998:2576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005643
VERSION     KCVT01005643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12998:2576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83168.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggga tcactactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01005644             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17226:23474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005644
VERSION     KCVT01005644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17226:23474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83169.1"
                     /translation="CMQSLEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctaatttcac actgataatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005645             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8905:10358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005645
VERSION     KCVT01005645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8905:10358"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83170.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc agtttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01005646             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:3588:11286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005646
VERSION     KCVT01005646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3588:11286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..383
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83171.1"
                     /translation="CQQHNSYPRTF"
     J_segment       385..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          109 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggta ccagatgtga catccagatg acccagtctc
      121 catcttcctt gtctgcatct gtaggagaca gagtcaccat cacttgccaa gccagtcagg
      181 gtattggcaa ctggttagcc tggtatcggc agaaaccagg gaaagcccct aagctcctga
      241 tctatgctgc atccagttta caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcagcagca taatagttat cctcggacgt tcggccaagg gaccaaggtg gaaatcaagc
      421 gag
//
LOCUS       KCVT01005647             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13856:13829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005647
VERSION     KCVT01005647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13856:13829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..274
                     /note="immunoglobulin light chain variable region"
     V_region        5..274
     V_segment       5..236
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <214..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83172.1"
                     /translation="CMQALEFPFTF"
     J_segment       237..274
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>277
                     /gene="IGKC"
BASE COUNT           70 a           62 c           78 g           67 t
ORIGIN      
        1 acatgggcta gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac
       61 ctgcagaagc caggccagtc tccacagctc ttgatttatg aggtttccaa ccgggcctct
      121 ggagtcccag acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc
      181 agagtggagg ctgaggatgt tggggtttat tactgtatgc aagctctaga gtttccattc
      241 accttcggcc ccgggaccaa agtggatatc aaacgag
//
LOCUS       KCVT01005648             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:25733:18168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005648
VERSION     KCVT01005648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25733:18168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83173.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc agtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005649             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21932:11549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005649
VERSION     KCVT01005649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21932:11549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83174.1"
                     /translation="CQQGKSNPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          112 c          114 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgtcccagt
      121 ctccatcctc cctgtctgca tccgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattag tgattcttta aattggtatc aacagaaacc ggggagagcc cctaagctcc
      241 tgatctttta tgcaaacagt ttggcaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagta gcctgcagcc tgaagatttt gcgacttatt
      361 actgtcaaca gggtaaaagt aatcctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005650             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22719:13442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005650
VERSION     KCVT01005650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22719:13442"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83175.1"
                     /translation="CQQYNSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          114 c          109 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcacct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc atccattttg gaaagtgggg tcccagcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005651             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14080:3458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005651
VERSION     KCVT01005651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14080:3458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83176.1"
                     /translation="CQQYNSLPWTF"
     J_segment       385..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          114 c          110 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattacgat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcaccc tcacttgccg ggcaagtcag
      181 gacattagca cttttttaaa ttggtatcaa cagagaccgg ggaaagcccc taagctcctg
      241 atctattatg caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cactggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc aacttattac
      361 tgtcaacagt ataatagttt accttggacg ttcggccagg gggccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005652             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25102:6055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005652
VERSION     KCVT01005652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25102:6055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83177.1"
                     /translation="CMQAREFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          127 c          112 g          103 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtaaggagg ggaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgctggggtt tattactgca tgcaagctcg agagtttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01005653             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23243:15969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005653
VERSION     KCVT01005653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23243:15969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83178.1"
                     /translation="CQQDFDWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           99 a          125 c          114 g           89 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gatatcaccg gagaagttgt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcaacacctt aacctggtac cggcacaatc ctgggcaggc tcccaagctc
      241 ctcctctatg gtgcatccac cagggccacc ggcatcccag acaggttcag tgccagtggg
      301 tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt tggaatttat
      361 tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01005654             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22192:10945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005654
VERSION     KCVT01005654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22192:10945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83179.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          104 a          121 c          110 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 atattagcac ctggttggcc tggtatcaac agagaccagg gaaagcccct aaggtcctga
      241 tctataggac atccaatttg gaaacagggg tcccatccag gttcagtgga accggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gatctcaaag
      421 gag
//
LOCUS       KCVT01005655             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:12501:16577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005655
VERSION     KCVT01005655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12501:16577"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..371
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83180.1"
                     /translation="CQQHNTYPYTF"
     J_segment       372..409
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT          102 a          116 c          103 g           91 t
ORIGIN      
        1 acatgggact caggacacag catggacatg agggtccccg ctcagctcct ggggctcctg
       61 ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc atcctccctg
      121 tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg cactagtaat
      181 gatttagcct ggtatcagca gaaaccaggg aaagccccga agcccctgat cttttacgca
      241 tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc
      301 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagcat
      361 aatacttacc cgtacacttt tggccagggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005656             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13131:11123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005656
VERSION     KCVT01005656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13131:11123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83181.1"
                     /translation="CLQFKTYPNSF"
     J_segment       385..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           97 a          118 c          106 g          102 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct cagctcctca
      241 tctatgctgc atccagtttg gccggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt ctctctcacc atcaccagcc tgcagcctga agattttgca acttatttct
      361 gtctgcagtt taaaacttac ccgaacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005657             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16496:15955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005657
VERSION     KCVT01005657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16496:15955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83182.1"
                     /translation="CLQGDTSPFSF"
     J_segment       389..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          114 c          112 g           97 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagccagg
      181 acattaacga ttatttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tctatgctgc atccagtttg gagagtgggg tcccatctag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga ggattttgca acttattact
      361 gtctacaggg tgatacttcc ccgtttagtt tcggcggagg gacccaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005658             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15232:10813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005658
VERSION     KCVT01005658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15232:10813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..233
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <211..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83183.1"
                     /translation="CMQPLEFPWTF"
     J_segment       234..271
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>274
                     /gene="IGKC"
BASE COUNT           70 a           59 c           82 g           63 t
ORIGIN      
        1 acatggggtc agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg
       61 cagaagccag gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga
      121 gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga
      181 gtggaggctg aggatgttgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg
      241 ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005659             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12830:9676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005659
VERSION     KCVT01005659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12830:9676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83184.1"
                     /translation="CQQYNSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatcggcag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 tagcagttat ttagcgtggt atcggcagaa gccagggaaa gccccggagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaagattc agcggcagtg catctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgactcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005660             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11513:16193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005660
VERSION     KCVT01005660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11513:16193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83185.1"
                     /translation="CQQYNSDWRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac tggcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005661             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12638:15800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005661
VERSION     KCVT01005661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12638:15800"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83186.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          123 c          122 g           97 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagagaggat ggaaacacct atttggactg gtacctgcag aggccaggcc
      241 agactcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgaag
      361 atcttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005662             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:11081:6236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005662
VERSION     KCVT01005662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11081:6236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83187.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtctatttt
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005663             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12674:9619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005663
VERSION     KCVT01005663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12674:9619"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83188.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005664             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14301:17228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005664
VERSION     KCVT01005664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14301:17228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83189.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcttggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctatttcgc atccactttg gaaagtggcg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcaacagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005665             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19177:8641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005665
VERSION     KCVT01005665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19177:8641"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..312
                     /note="immunoglobulin light chain variable region"
     V_region        113..312
     V_segment       113..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83190.1"
                     /translation="CMQALEFPLTF"
     J_segment       276..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           81 c           86 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagtctc
      121 cacagctctt gatttatgag gtttccaatc gggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggagcct gaggatgttg
      241 gggtttatta ctgcatgcaa gctctagaat ttcctctcac tttcggtgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01005666             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20033:12105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005666
VERSION     KCVT01005666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20033:12105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83191.1"
                     /translation="CMQALDFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          108 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca cagctcttga tttttgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactaattt cacactgaaa atcagcagtg tggaggctga
      361 ggatgttggg gtctattact gcatgcaagc tctagacttt ccttacagtt ttggccaggg
      421 gaccacagtg gagattaaac gag
//
LOCUS       KCVT01005667             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9719:19796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005667
VERSION     KCVT01005667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9719:19796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83192.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          101 a          111 c          106 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc cagctgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01005668             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:26100:9065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005668
VERSION     KCVT01005668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26100:9065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83193.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          117 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01005669             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16545:5836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005669
VERSION     KCVT01005669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16545:5836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83194.1"
                     /translation="CMQALEFPWTF"
     J_segment       348..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           88 a           98 c          109 g           92 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgtaggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggattggtac ctgcagaagc
      181 caggccagtc tccacacctc ttgatttatg aagtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttccttgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01005670             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8587:14370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005670
VERSION     KCVT01005670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8587:14370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..437
                     /note="immunoglobulin light chain variable region"
     V_region        113..437
     V_segment       113..397
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83195.1"
                     /translation="CQQYIDLLPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          124 c          122 g           94 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggatccca gataccgccg gagaaattgt
      121 aatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaacagcca ccctctcctg
      181 cagggccagt gagagtgttg gcagctactt agcctggtac cagcagaaac ctgggcaggc
      241 tcccaagctc cttgtccata gtgcatactt cagggccact ggcatcccag acaggttcag
      301 tggcagcggg tctaggacag agttcactct caccattagc agcctggagc ctgaagatgt
      361 tggagtttat cactgtcagc agtatattga cttgcttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01005671             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16009:13231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005671
VERSION     KCVT01005671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16009:13231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..388
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83196.1"
                     /translation="CQLGNRTPPYSF"
     J_segment       392..429
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          104 a          118 c          105 g          105 t
ORIGIN      
        1 acatggggac gtttagcctg tgacagggct cagctaacat aatggatttt caggctcaaa
       61 ttttcatctt ccttctgctc agtgtcacag tgtccaatgg agaaattgtg ctgacccagt
      121 ctccaacatc cttggctgtc tcccagggag agagagtcac catctcctgc acggccagct
      181 caagtgtaag caccagctac tttcactggt accaacaaaa gccaggattc cctccaaggc
      241 ttcttgtctt tagaacatca agtctggctt ctggggtccc agccaggttc agtggcagcg
      301 gttctggggc ctcttccacg ctcacaatca gcaccatgga ggctgaagat gctgcatact
      361 attactgtca actggggaat cgcactccgc cgtacagttt tggccagggg accaaagtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01005672             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18743:18900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005672
VERSION     KCVT01005672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18743:18900"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83197.1"
                     /translation="CLQYKNFPLSF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          112 c          106 g          103 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatgggca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccaggtgtg acatccagat gactcagtct
      121 ccgtcttccc tgtctgcatc tctaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gatattaaca gttatttaaa ttggtttcag cagaaaccag ggaaagcccc taagctcctg
      241 atctatggtg catccagttt ggaaagtgag gtcccattaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttatttc
      361 tgtctacagt ataaaaattt cccgctctct ttcggcggag ggaccagggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01005673             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9411:17859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005673
VERSION     KCVT01005673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9411:17859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83198.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005674             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10393:8191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005674
VERSION     KCVT01005674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10393:8191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83199.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctcca gaagccaggc
      241 cagtctccac atctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccagggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005675             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12906:12634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005675
VERSION     KCVT01005675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12906:12634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..435
                     /note="immunoglobulin light chain variable region"
     V_region        100..435
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83200.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>442
                     /gene="IGKC"
BASE COUNT           95 a          123 c          119 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgta tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgcgga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccagggg
      421 accaaggtgg aaatcgaacg ag
//
LOCUS       KCVT01005676             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21287:17123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005676
VERSION     KCVT01005676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21287:17123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83201.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcgt ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01005677             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:8164:8819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005677
VERSION     KCVT01005677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8164:8819"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83202.1"
                     /translation="CMQSTKDPLTF"
     J_segment       399..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          124 c          106 g          105 t
ORIGIN      
        1 acatggggat caggactcct cagttcatct tctcacgatg agactccctg ctcagctcct
       61 cgggctgttg atgctctggg tccctggatc cagtggcgat attttgctga cccagactcc
      121 actctcgctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 ccttctgcat aataatggat acacctattt acattggtac ctgcagaagc caggccagtc
      241 tccacggctc ctgatctata aagttaccaa tcgagaatct ggggtcccag acaggttcag
      301 cggcagtggg tcaggcatag atttcacact gaaaatcagc agggtggagc ctgaggatgt
      361 tggtgtttat tactgcatgc aaagtacaaa agatcccctc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01005678             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15382:16123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005678
VERSION     KCVT01005678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15382:16123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83203.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          118 c          124 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttcca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cgcagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005679             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10965:9652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005679
VERSION     KCVT01005679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10965:9652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83204.1"
                     /translation="CQQVLTNPAF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          101 a          112 c          106 g           98 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccaggtgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataggaa tttagcgtgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 atgctgcatc cagattgcaa agtgggtttc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcaacctac agcctgaaga ttctgcaatt tattactgtc
      361 aacaggttct tactaacccg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01005680             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24936:16253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005680
VERSION     KCVT01005680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24936:16253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83205.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgctact tattactgtc
      361 aacaatatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005681             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21329:4196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005681
VERSION     KCVT01005681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21329:4196"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83206.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          120 c          107 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca actgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005682             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18623:13348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005682
VERSION     KCVT01005682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18623:13348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83207.1"
                     /translation="CQRYSYSTWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          121 c          116 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg ccaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagcttg gtttggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtatatt
      361 actgtcagag gtatagttac tccacgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005683             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15539:16371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005683
VERSION     KCVT01005683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15539:16371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..270
                     /note="immunoglobulin light chain variable region"
     V_region        8..270
     V_segment       8..228
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83208.1"
                     /translation="CQQYDSDSLTF"
     J_segment       233..270
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>273
                     /gene="IGKC"
BASE COUNT           71 a           66 c           73 g           63 t
ORIGIN      
        1 acatgggcat cacttgtcgg gcgactcagg acattcgcag ttatttagcg tggtatcagc
       61 agaaaccagg gaaagccccg aggcccttga tctattacgc gtccactttg gaaagtgggg
      121 tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc atcagcagcc
      181 tgcagcctga agattttgca acttattact gtcaacaata tgacagtgat tcgctcactt
      241 tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005684             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10003:13712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005684
VERSION     KCVT01005684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10003:13712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83209.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01005685             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15521:4897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005685
VERSION     KCVT01005685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15521:4897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83210.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          116 c          109 g           89 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagtc
      181 aggatattaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaaactcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcggt ggaagtggat
      301 ctgggacaga tttcactctc accattagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005686             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7609:6004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005686
VERSION     KCVT01005686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7609:6004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..394
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83211.1"
                     /translation="CGQGTQLPPTF"
     J_segment       398..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           98 a          123 c          118 g           95 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgatgactc agtctccact
      121 ctccctgccc atcacccctg gacagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tgtacacatc aatggaaaca catacttgag ttggtatcac cagaagccag gccaacctcc
      241 aaggcgccta atttatgagg tttcttaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 ggtttattac tgcgggcaag gtacacagct tcctcccacg ttcggccaag ggaccaaggt
      421 ggacatcaaa cgag
//
LOCUS       KCVT01005687             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20474:5563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005687
VERSION     KCVT01005687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20474:5563"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83212.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005688             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18883:18500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005688
VERSION     KCVT01005688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18883:18500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83213.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc ctcggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005689             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19446:6546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005689
VERSION     KCVT01005689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19446:6546"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83214.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          124 c          114 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatgaaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01005690             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14572:20514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005690
VERSION     KCVT01005690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14572:20514"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83215.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01005691             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8892:14382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005691
VERSION     KCVT01005691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8892:14382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83216.1"
                     /translation="CMQALEFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          125 c          116 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccgctctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgaag tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgat aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcacc ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01005692             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12336:8181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005692
VERSION     KCVT01005692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12336:8181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83217.1"
                     /translation="CLQGYSAPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          118 c          107 g           98 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgct tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgattattta agttggtatc agcagaaacc aggaaaaact cctcagcgcc
      241 tgatctatgc tgcatccagt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcatcttatt
      361 actgtctaca gggttatagt gccccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01005693             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:21058:17308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005693
VERSION     KCVT01005693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21058:17308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..365
                     /note="immunoglobulin light chain variable region"
     V_region        88..365
     V_segment       88..323
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83218.1"
                     /translation="CQQYNSEPRTF"
     J_segment       331..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           92 a           98 c          101 g           77 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagtc accatcactt gtcgggcgag
      121 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaac ccccgaagcc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa cagtataaca gtgagccgcg cactttcggt ggagggacca aggttgagat
      361 caaacgag
//
LOCUS       KCVT01005694             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9616:12595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005694
VERSION     KCVT01005694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9616:12595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..377
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83219.1"
                     /translation="CQHSYGTLTWAF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gggacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taagaactat ttacattggt atcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc actttgcaaa gtggggtccc atcaaggttc accggcagtg gatctggggc
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat ggtaccctca cgtgggcgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01005695             270 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13507:15414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005695
VERSION     KCVT01005695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 270)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13507:15414"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    21..267
                     /note="immunoglobulin light chain variable region"
     V_region        21..267
     V_segment       21..229
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83220.1"
                     /translation="CQQYNSDPFTF"
     J_segment       230..267
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>270
                     /gene="IGKC"
BASE COUNT           77 a           68 c           65 g           60 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca taagaagtta tttagcgtgg tatcagcaga
       61 aaccaggcaa acccccgaag cccttgatct attacgcatc cgttttggaa agtggggtcc
      121 catcaaggtt cagtggcagt ggatctggga cagaattcac tctcaccatc agcagtctgc
      181 agcctgagga ttttgcaact tattactgtc aacaatataa cagtgaccca ttcactttcg
      241 gccccgggac caaactggat accaaacgag
//
LOCUS       KCVT01005696             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19010:15796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005696
VERSION     KCVT01005696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19010:15796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83221.1"
                     /translation="CQQVLTNPAF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          101 a          113 c          105 g           98 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccaggtgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataggaa tttagcgtgg tatcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 atgctgcatc cagattgcaa agtgggtttc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcaacctac agcctgaaga ttctgcaatt tattactgtc
      361 aacaggttct tactaacccg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01005697             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21406:6394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005697
VERSION     KCVT01005697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21406:6394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..372
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83222.1"
                     /translation="CQQYDDYPWTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac aaagtcacca tcacttgcca tgccagtcag
      181 ggtattagta gtcggttagt ctggtatcag cagaaagcag ggaaagcccc taagcccctg
      241 atgtatgatg catccagttt acacagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgatgatta cccgtggacc ttcggccaag ggaccaaggt ggaaatcaag
      421 cgag
//
LOCUS       KCVT01005698             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10299:14682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005698
VERSION     KCVT01005698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10299:14682"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..282
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83223.1"
                     /translation="CMQALEFPLTF"
     J_segment       285..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           72 a           84 c           88 g           78 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtcaga cactgatttc actctgaaaa tcagcagagt ggaggctgag
      241 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      301 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005699             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21860:6026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005699
VERSION     KCVT01005699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21860:6026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83224.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaagttgga aatcaaacga g
//
LOCUS       KCVT01005700             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19337:3814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005700
VERSION     KCVT01005700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19337:3814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83225.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tgtgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005701             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:9363:14190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005701
VERSION     KCVT01005701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9363:14190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83226.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtatc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaat tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005702             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21891:16934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005702
VERSION     KCVT01005702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21891:16934"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83227.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tccagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005703             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:5597:12835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005703
VERSION     KCVT01005703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:5597:12835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83228.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc ttcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacctatta
      361 ctgtcaacag tatgacagtg atccgttcac tttcggtggg gggaccaagg tagacatcaa
      421 acgag
//
LOCUS       KCVT01005704             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:8284:7347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005704
VERSION     KCVT01005704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:8284:7347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..397
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83229.1"
                     /translation="CQQYYSTPWTF"
     J_segment       398..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          104 a          112 c          121 g          101 t
ORIGIN      
        1 acatggggct acaacaggca ggcaggggca gcaagatggt gtcacagacc caagtcttca
       61 tttccctgtt gctctggatc tctggtgcct gtggggacat tgtgatgacc cagtcgccag
      121 actccctggc tgtgtctctg ggagagaggg tcaccatcaa ctgcaagtcc agccagagtc
      181 ttttacgcgt ctccaacaat aggaactact tagcctggta tcagcagaaa ccagggcagg
      241 ctcctaaatt gctcatttac tgggcatcta cccgggaatt cgggatccct aaccgattca
      301 gtggcagtgg atctgggtca gatttcactc tcaccatcag tggcctgcag gctgaagatg
      361 tggcagtgta ttactgtcag cagtattata gcactccgtg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01005705             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:13187:13105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005705
VERSION     KCVT01005705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13187:13105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83230.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005706             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21765:16737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005706
VERSION     KCVT01005706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21765:16737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..397
                     /note="immunoglobulin light chain variable region"
     V_region        76..397
     V_segment       76..359
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83231.1"
                     /translation="CQQGSPFPWTF"
     J_segment       360..397
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>400
                     /gene="IGKC"
BASE COUNT           99 a          107 c          101 g           93 t
ORIGIN      
        1 acatggggca ggaagatgtt gtctccatca caactcattg ggtttctgct gctctgggtt
       61 ccagcctcca agggtgaaat tgtgctgact cagtctccag cctttcggtc tgtgactcta
      121 aaggagaaag tcaccatcac ctgccaggcc agtcagagca ttggtaatag cttacactgg
      181 taccagcaga aaccggatca gtctccaaag ctcctcatca aatatgcttc ccagtccatc
      241 tcaggggtcc cctcaaggtt cagtggcagt ggatctggga cagatttcac cctcaccatc
      301 aatagcctgg aagctgaaga tgctgcgacg tattactgtc agcagggaag tcctttcccg
      361 tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01005707             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17378:12622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005707
VERSION     KCVT01005707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17378:12622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83232.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggccacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005708             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15606:16869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005708
VERSION     KCVT01005708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15606:16869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83233.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaaa caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005709             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17988:17319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005709
VERSION     KCVT01005709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17988:17319"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83234.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtactg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005710             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:12386:13116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005710
VERSION     KCVT01005710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12386:13116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83235.1"
                     /translation="CHQYNNLPLTF"
     J_segment       308..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           94 a           90 c           79 g           84 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct ccctgtctgc
       61 ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacatta acatttattt
      121 aaattggtat cagcagaaac cggggaaagc ccctaagctc ctgatctatt atgcaaatcg
      181 tttggaaact ggggtcccgt caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcaac agcctgcaac ccgaagattt tgcaacttat tactgtcacc agtataataa
      301 tttaccactc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005711             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14152:15544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005711
VERSION     KCVT01005711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14152:15544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83236.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005712             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16734:15728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005712
VERSION     KCVT01005712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16734:15728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83237.1"
                     /translation="CMQSLEIPPTF"
     J_segment       408..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           94 a          122 c          123 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtgg ggatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agccactgat ttcacactga aaatcagcag ggtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa tctctagaga ttcctcccac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01005713             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16596:7653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005713
VERSION     KCVT01005713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16596:7653"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83238.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          109 c          110 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattgagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcgttaacg tttatttaaa ttggtatcaa cagaaaccgg ggaaagcccc taagcccctg
      241 atcttttatg caaaccgttt ggaacgtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aagttattat
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005714             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10728:2509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005714
VERSION     KCVT01005714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10728:2509"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83239.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttcttttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005715             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10663:12164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005715
VERSION     KCVT01005715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10663:12164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83240.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccgggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005716             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18644:20250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005716
VERSION     KCVT01005716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18644:20250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83241.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgcc aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005717             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13493:13226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005717
VERSION     KCVT01005717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13493:13226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83242.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          114 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagat actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005718             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19176:6017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005718
VERSION     KCVT01005718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19176:6017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83243.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          117 c          106 g           90 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttacgaatga tttagcctgg tatcaacaga aaccaggtaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agtctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01005719             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12882:5464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005719
VERSION     KCVT01005719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12882:5464"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83244.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          122 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaagcacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gaccaaacga g
//
LOCUS       KCVT01005720             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13912:8974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005720
VERSION     KCVT01005720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13912:8974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83245.1"
                     /translation="CLQFKTFPYRF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           97 a          119 c          105 g          102 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct aagctcctca
      241 tctatgctgc atccactttg gccggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagactt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagtt taaaactttc ccgtaccgtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005721             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6390:6288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005721
VERSION     KCVT01005721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6390:6288"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83246.1"
                     /translation="CQQYSDFLLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           95 a          124 c          114 g           91 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gatcccagat accgccggag aaattgtaat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa acagccaccc tctcctgcag ggccagtgag
      181 agtgttggca ccttcgtagc ctggtaccaa cagaaacctg ggcaggctcc caggctcctt
      241 gtccatagtg cattcttcag ggccactggc atcccagaca ggttcagtgg cagcgggtct
      301 aggacagagt tcactctcac cattaacacc ctggagcctg aggatgttgg actttatcac
      361 tgtcagcagt atagtgactt cctgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005722             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18430:5393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005722
VERSION     KCVT01005722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18430:5393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..437
                     /note="immunoglobulin light chain variable region"
     V_region        101..437
     V_segment       101..400
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83247.1"
                     /translation="CMQSTKDPRTF"
     J_segment       402..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          103 a          121 c          116 g          100 t
ORIGIN      
        1 acatgggggg gatcaggact cctcagttca tcttctcacg atgagactcc ctgctcagct
       61 cctcgggctg ttgatgctct gggtccctga gtccagtggc gatattgtgc tgacccagac
      121 tccactctcg ctgcccgtca cccctggaga gccggcctcc atctcctgca ggtctagtca
      181 aggtcttctg catagtaatg gaaacaccta tttgcattgg taccaacaga agccaggcca
      241 gtctccacgc ctcctgatct ataaagttac caatcgggaa tctggggtcc cagacaggtt
      301 cagtggcagt gggtcaggca cagatttcac actgacaatc agcagggtgg agcctgagga
      361 tgttggtatt tattactgca tgcaaagtac aaaagatccc cggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005723             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13882:8278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005723
VERSION     KCVT01005723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13882:8278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83248.1"
                     /translation="CVQAIAFPYSF"
     J_segment       393..430
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           92 a          119 c          116 g          106 t
ORIGIN      
        1 acatgggagg actcctcagt tcaccttctc acaatgaggc tccctgctca gttcctgggg
       61 ctgctgatgc tctggctccc tggatccagt ggggatattg tgatgaccca gactcctctc
      121 tccctgtcca tcacccctgg agagccggcc tccatctcct gcaggtctag tcagagcctc
      181 cttcatagta atggaaacac ctattttcac tggtacctgc agaagccagg ccattctccg
      241 cagctcctga tttatggggg ttccaacaga gcctctggag tcccagacag gttcagtggc
      301 agtgggtcag gcactgattt cacactgaaa atcagcaagg tggaggcgga ggatgttggc
      361 gtttattact gcgtgcaagc tatagcgttt ccgtacagtt ttggccaggg gaccaaagtg
      421 gagatcaaac gag
//
LOCUS       KCVT01005724             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:9482:4312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005724
VERSION     KCVT01005724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9482:4312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83249.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005725             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10692:6586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005725
VERSION     KCVT01005725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10692:6586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83250.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005726             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22024:6352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005726
VERSION     KCVT01005726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22024:6352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83251.1"
                     /translation="CQQYNSLPYIF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          102 a          105 c          100 g           97 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgcttc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag gacattagcg tttttttaaa
      181 ttggtatcag cagaaaccgg ggaaagcccc taaacccctg atctattatg caaaccgttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaacctg aagattttgc aacttattac tgtcaacagt ataatagttt
      361 accgtacatt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01005727             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5395:16215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005727
VERSION     KCVT01005727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5395:16215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83252.1"
                     /translation="CQQGYNTPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          117 c          112 g           88 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcagggtat
      181 tagcaggtgg ttagcctggt atcagcagaa accagggaaa gcccctagac tcctgatcta
      241 taaggcgtcc actttggcaa gtggggtccc atcaaccttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagggttac aataccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005728             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15330:20565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005728
VERSION     KCVT01005728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15330:20565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..434
                     /note="immunoglobulin light chain variable region"
     V_region        97..434
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83253.1"
                     /translation="CMQSLDFPLTF"
     J_segment       399..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>439
                     /gene="IGKC"
BASE COUNT           94 a          120 c          120 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgttatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcctggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac agatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcagtctcta gattttccgc tcaccttcgg tggagggacc
      421 aaggtggaga tcaatcgag
//
LOCUS       KCVT01005729             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17824:9206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005729
VERSION     KCVT01005729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17824:9206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83254.1"
                     /translation="CQQGHSYPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          117 c          107 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggcgataat ttatattggt atcaacacaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc agtttacaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggattttgct ctcaccatca gcggcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcat agttacccac tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005730             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17652:13077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005730
VERSION     KCVT01005730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17652:13077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83255.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcttactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005731             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:25655:16963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005731
VERSION     KCVT01005731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25655:16963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83256.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg cgtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005732             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:4995:10737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005732
VERSION     KCVT01005732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:4995:10737"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83257.1"
                     /translation="CMQALEFPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc actggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagg
      181 ctcttggata atgaggatga aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttccat tcactttcgg ccccgggacc
      421 aagctggaaa tcaaacgag
//
LOCUS       KCVT01005733             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:4406:8367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005733
VERSION     KCVT01005733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4406:8367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83258.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005734             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:26774:19472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005734
VERSION     KCVT01005734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26774:19472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83259.1"
                     /translation="CQQYNSLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          109 a          111 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatagttta cctcggacgt tcggccaagg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01005735             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13185:7396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005735
VERSION     KCVT01005735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13185:7396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83260.1"
                     /translation="CQQYNSLPWTF"
     J_segment       406..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          117 a          114 c          116 g           99 t
ORIGIN      
        1 acatggggag gctggacaga cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag gtgccagatg
      121 tgacattcag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgc cgggcaagtc agggcattag ttattattta aattggtatc aacagaaacc
      241 ggggaaagcc cctaaggtcc tgatctatta cacaaaccgt ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc
      361 tgaggatttt gcaagttatt actgtcaaca atataatagt ttaccgtgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01005736             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11273:13380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005736
VERSION     KCVT01005736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11273:13380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83261.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat tttctgtagg gctagtcaga
      181 gcctcttgga tcgtgacgat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagccaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005737             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15501:9215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005737
VERSION     KCVT01005737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15501:9215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83262.1"
                     /translation="CQQGHSYPWTF"
     J_segment       383..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          110 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag tcgagtctag
      181 gcattggcaa atttttaaat tggtatcagc agaaaccagg gaaagccccc aaactcctga
      241 tctatagggc atccagtttg caaactggga ttccctctcg gttcagcgtc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc gcttattact
      361 gtcaacaggg tcatagttac ccgtggacgt tcggccaagg gaccaaggtg gagatgaaac
      421 gag
//
LOCUS       KCVT01005738             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:14210:10440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005738
VERSION     KCVT01005738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14210:10440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83263.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtatc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgct gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005739             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7664:5832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005739
VERSION     KCVT01005739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7664:5832"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83264.1"
                     /translation="CQQYDSDPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          110 c          112 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattaggaat tatttagcgt ggtatcagca gaaaccaggg aaagccccga aggccttgat
      241 ctattacaca tccattttgg aaaatggggt cccatcaagg ttcagcggcg gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcaggctgag gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005740             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22167:12203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005740
VERSION     KCVT01005740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22167:12203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83265.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005741             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24945:13489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005741
VERSION     KCVT01005741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24945:13489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83266.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          122 c          118 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agaacctcct ggatagtgag gatggaaaca cctatttgca ctggtacctg aagaagccag
      241 gccagtctcc acagctctta atttatgaag tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005742             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15899:9328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005742
VERSION     KCVT01005742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15899:9328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83267.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          118 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caatggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaagatg gaaacaccta tttggagtgg tatctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01005743             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17914:19115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005743
VERSION     KCVT01005743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17914:19115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83268.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat caccagagtg gaggctgagg
      361 atgttggggt ttactactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01005744             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17100:13580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005744
VERSION     KCVT01005744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17100:13580"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83269.1"
                     /translation="CQQYSTLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          109 c          111 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacagttat ttaaattggt atcagcagag accggggaaa gcccctaagg tcctgatgta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcgactt attactgtca
      361 acagtatagt actttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005745             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21828:17438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005745
VERSION     KCVT01005745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21828:17438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83270.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          117 c          121 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtgcggaca ttgtgatgac ccagactcca
      121 ctctccctgg ccgtcactct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggatc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01005746             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14205:6447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005746
VERSION     KCVT01005746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14205:6447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83271.1"
                     /translation="CQQYNSLPLSF"
     J_segment       384..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          110 c          102 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccaa atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcaatttt ttaaattggt atcagcagaa accggggaaa gcccctaaga tcctgatcta
      241 ttatggaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca acctgaggat tttggagttt attactgtca
      361 acaatataat agtttaccac tctctttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01005747             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:24415:3062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005747
VERSION     KCVT01005747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24415:3062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83272.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005748             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12927:17820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005748
VERSION     KCVT01005748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12927:17820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83273.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tgtcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgagttt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005749             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:11280:11657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005749
VERSION     KCVT01005749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11280:11657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..444
                     /note="immunoglobulin light chain variable region"
     V_region        105..444
     V_segment       105..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83274.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..444
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT           98 a          123 c          120 g          106 t
ORIGIN      
        1 acatgggggt gactgatcac gactcctcag gtcaccttct cacaatgagg ctccctgctc
       61 agctcctggg actgctaatg ctctggctcc ctggatccaa tggggacatt ctgatgaccc
      121 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      181 gtcagagcct cctggatggt gaagatggaa acacctattt gcactggtac ctgaagaggc
      241 caggccagtc tccacatctc ttaatttatg aggtttccaa ccgggcctct ggagtcccag
      301 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      361 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttccgctc actttcggtg
      421 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005750             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15708:10478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005750
VERSION     KCVT01005750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15708:10478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83275.1"
                     /translation="CQKYSSFPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          125 c          108 g           93 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacatg ggcaggcccc cagactcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagttg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aaggctttgc agtgtattac
      361 tgtcagaagt atagtagttt cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01005751             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19207:16638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005751
VERSION     KCVT01005751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19207:16638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..398
                     /note="immunoglobulin light chain variable region"
     V_region        80..398
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83276.1"
                     /translation="CQQHNGYPPTF"
     J_segment       367..398
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>404
                     /gene="IGKC"
BASE COUNT          100 a          113 c          103 g           88 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattacga atgatttagc
      181 ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg atctattacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattat tgtcaacagc ataatggata
      361 ccctccgacg ttcggccaag ggaccagggt ggaaatcaga cgag
//
LOCUS       KCVT01005752             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13129:6278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005752
VERSION     KCVT01005752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13129:6278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83277.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaagt cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagaatttcc gtggacgttc ggcccaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005753             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11950:11328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005753
VERSION     KCVT01005753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11950:11328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..401
                     /note="immunoglobulin light chain variable region"
     V_region        110..401
     V_segment       110..363
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83278.1"
                     /translation="CMQALEFPLTF"
     J_segment       364..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           92 a          101 c          116 g           95 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 catgtcctgc aggtctagtc agagcctcgt ggctagtgag gatggaaaca cgtatttaga
      181 atggtacctg cagaagccag gccagtctcc acagctcttg atttatgagg tttccaaccg
      241 ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa
      301 aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaag ctctagagtt
      361 tccgctcact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005754             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11688:17312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005754
VERSION     KCVT01005754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11688:17312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83279.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgacg tttccagccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005755             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11321:13237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005755
VERSION     KCVT01005755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11321:13237"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83280.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01005756             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6179:18233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005756
VERSION     KCVT01005756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6179:18233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83281.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca acataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005757             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13820:4081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005757
VERSION     KCVT01005757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13820:4081"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..399
                     /note="immunoglobulin light chain variable region"
     V_region        78..399
     V_segment       78..352
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83282.1"
                     /translation="CQQHNNYSPTF"
     J_segment       365..399
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>402
                     /gene="IGKC"
BASE COUNT           98 a          113 c          102 g           89 t
ORIGIN      
        1 acatggggag catggacatg agggtccccg ctcagctcct ggggctcctg ctgctctggc
       61 tcccaggtgc cagatgtgac atccagatga cccagtctcc accctccctg tctgcatctg
      121 taggagacac agtcaccatc acttgtcggg caagtcaggg cattagcaat gatttagcct
      181 ggtatcagct gaaaccaggg aaagccccga agcccctgat ctattacgca tccaatttgg
      241 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc actctcacca
      301 tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagcat aataattact
      361 ctcccacttt cggcggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005758             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17645:8405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005758
VERSION     KCVT01005758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17645:8405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83283.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          117 c          109 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcactg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atttctgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005759             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20743:7294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005759
VERSION     KCVT01005759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20743:7294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..297
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83284.1"
                     /translation="CQQHNNYSPTF"
     J_segment       310..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           91 a           96 c           82 g           78 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccaccct ccctgtctgc
       61 atctgtagga gacacagtca ccatcacttg tcgggcaagt cagggcatta gcaatgattt
      121 agcctggtat cagctgaaac cagggaaagc cccgaagccc ctgatctatt acgcatccaa
      181 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac aacataataa
      301 ttactctccc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005760             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5690:15018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005760
VERSION     KCVT01005760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5690:15018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..375
                     /note="immunoglobulin light chain variable region"
     V_region        126..375
     V_segment       126..338
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83285.1"
                     /translation="CQQDYHWPPTF"
     J_segment       341..375
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>378
                     /gene="IGKC"
BASE COUNT           92 a          107 c          101 g           78 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccag tcagagtgtt ggcagcacct taacctggta ccaccagaag cctgggcagg
      181 ctcccaagct cctcatctat ggtccttcca tccgggccag cggcatccca gacaggttca
      241 gtggcagtgg gtctggaaca gaatttactc tcaccatcag cagcctggag actgaagatg
      301 ttggagttta tttctgtcag caggattatc actggcctcc gacgttcggc caagggacca
      361 aggtggaaat caaacgag
//
LOCUS       KCVT01005761             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25211:7253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005761
VERSION     KCVT01005761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25211:7253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83286.1"
                     /translation="CQQYNSLPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          112 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggggaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtag ttttttaaat tggtatcagc agaaaccggg gaaagcccct cagctcctga
      241 tctactatgc aaaccgtttg gagagtgggg tcccatcaag gttcagcggc aatggatctg
      301 ggacagaatt cactctcacc atcagcaccc tgcaacctga ggattttgca atttatcact
      361 gtcaacagta taatagttta ccgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005762             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16257:6974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005762
VERSION     KCVT01005762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16257:6974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..401
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83287.1"
                     /translation="CMQSTKDPLTF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          124 c          110 g          106 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc atcttctcac gatgagactc cctgctcagc
       61 tcctcgggct gttgatgctc tgggtccctg gatccagtgg cgatattttg atgacccaga
      121 ctccactctc gctgcccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 aaagccttct gcatagtaat ggatacacct atttgcattg gtacctgcag aagccaggcc
      241 agtctccacg gctcctgatc tataaagtta ccaatcggga atctggggtc ccagacaggt
      301 tcagcggcag tgggtcaggc atagatttca cactgaaaat cagcagggtg gagcctgagg
      361 atgttggtgt ttattactgc atgcaaagta caaaagatcc cctcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005763             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19097:20043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005763
VERSION     KCVT01005763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19097:20043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..358
                     /note="immunoglobulin light chain variable region"
     V_region        87..358
     V_segment       87..326
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83288.1"
                     /translation="CQQYNSDPFTF"
     J_segment       327..358
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>367
                     /gene="IGKC"
BASE COUNT           96 a           98 c           94 g           79 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccagga gacagagtaa ccatcacttg tcgggcgagt
      121 caggacataa gaagttattt agcgtggtat cagcagaaac caggcaaagc cccgaagccc
      181 ttgatctatt acgcatccgt tttggaaagt ggggtcccat caaggttcag tggcagtgga
      241 tctgggacag aattcactct caccatcagc agtctgcaac ctgaggattt tgcaacttat
      301 tactgtcaac agtataacag tgacccattc actttcggcc ccgggaccaa actggatacc
      361 gagcgag
//
LOCUS       KCVT01005764             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17231:13201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005764
VERSION     KCVT01005764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17231:13201"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83289.1"
                     /translation="CQQVLTNPAF"
     J_segment       388..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          113 c          108 g           99 t
ORIGIN      
        1 acatgggggg gagtcagtct cagtcaggac acagcatgga catgagggtc cctgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgatatccag gtgacccagt
      121 ctccatctgc cttgtctgca tctgtaggag acagagtcac catctcttgc cgggcaagtc
      181 agaacattta taggaattta gcgtggtatc agcagaaacc agggaaagcc cctaaactcc
      241 tgatctatgc tgcatccaga ttgcaaagtg ggtttccctc tcggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcaaca acctacagcc tgaagattct gcaatttatt
      361 actgtcaaca ggttcttact aacccggcgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005765             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25246:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005765
VERSION     KCVT01005765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25246:7995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83290.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaggtca
      421 aacgag
//
LOCUS       KCVT01005766             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16885:6614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005766
VERSION     KCVT01005766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16885:6614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83291.1"
                     /translation="CMQVLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagttc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005767             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10836:3627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005767
VERSION     KCVT01005767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10836:3627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..375
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83292.1"
                     /translation="CQQVYSSPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          113 c          108 g          104 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccagat gacccagtct
      121 ccatctgcct tgtctgcatc tgtgggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata gttatttagc gtggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg tatccagatt gcaaagtggg gttccctctc ggttcagcgg cagtggaact
      301 gggacagatt tcactctcag catcagcagc ctacagcctg aagattctgc cggttattac
      361 tgtcaacagg tttatagtag tccattcact ttcggcccgg gaccaaactg gctatcaaac
      421 gag
//
LOCUS       KCVT01005768             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10760:4283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005768
VERSION     KCVT01005768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10760:4283"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83293.1"
                     /translation="CQQYNSEPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacta gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg agccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005769             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:24371:14717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005769
VERSION     KCVT01005769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24371:14717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83294.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagacttc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaca aaccaggcca
      241 gtctccagag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggctt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag gtcaaacgag
//
LOCUS       KCVT01005770             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23678:2879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005770
VERSION     KCVT01005770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23678:2879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83295.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          120 c          109 g           89 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005771             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8984:11077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005771
VERSION     KCVT01005771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8984:11077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83296.1"
                     /translation="CQQYNSLPYIF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          110 c          103 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagt gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgttttt ttaaattggt atcagcagaa accggggaaa gcccctaaac ccctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat agtttaccgt acatttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005772             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13703:17730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005772
VERSION     KCVT01005772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13703:17730"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83297.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          123 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgaag tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt cccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01005773             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22240:23133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005773
VERSION     KCVT01005773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22240:23133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83298.1"
                     /translation="CMQALDFPYSF"
     J_segment       405..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          120 c          117 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acagctcttg atttttgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gaaactaatt tcacactgaa aatcagcagt gtggaggctg
      361 aggatgttgg ggtctattac tgcatgcaag ctctagactt tccttacagt tttggccagg
      421 ggaccacagt ggagattaaa cgag
//
LOCUS       KCVT01005774             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14635:9871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005774
VERSION     KCVT01005774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14635:9871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..331
                     /note="immunoglobulin light chain variable region"
     V_region        12..331
     V_segment       12..295
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83299.1"
                     /translation="CQQYNSDPFTF"
     J_segment       296..331
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>336
                     /gene="IGKC"
BASE COUNT           90 a           87 c           80 g           79 t
ORIGIN      
        1 acatgggatg tgacgtccag atgacccagt ctccatcctc cctgtctgca tctgtaggag
       61 acagagtaac catcacttgt cgggcgagtc aggacataag aagttattta gcgtggtatc
      121 agcagaaacc aggcaaagcc ccgaagccct tgatctatta cgcatccgtt ttggaaagtg
      181 gggtcccatc aaggttcagt ggcagtggat ctgggacaga attcactctc accatcagca
      241 gtctgcagcc tgaagatttt gcaacttatt actgtcaaca gtataacagt gacccattca
      301 ctttcggccc cgggaccaaa ctggatatca accgag
//
LOCUS       KCVT01005775             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10736:14231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005775
VERSION     KCVT01005775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10736:14231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83300.1"
                     /translation="CQHSFRTPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          117 c          107 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcaccg tcacttgcag ggctagtgag
      181 agcgttaaca ccaaattaca ttggtatcaa caaaaaccag ggaaagcccc taagctcctg
      241 atctttgctg cgtccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggaacagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aactttttac
      361 tgtcagcata gttttcgtac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005776             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14232:7647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005776
VERSION     KCVT01005776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14232:7647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83301.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          113 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcgtggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01005777             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24184:9610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005777
VERSION     KCVT01005777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24184:9610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83302.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005778             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9181:16745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005778
VERSION     KCVT01005778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9181:16745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83303.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc acaagccagg
      241 ccagtctcca gagctcttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagat tggaggctga
      361 ggatgttggg ctttattact gtatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gaggtcaaac gag
//
LOCUS       KCVT01005779             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14561:13909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005779
VERSION     KCVT01005779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14561:13909"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83304.1"
                     /translation="CQQGYTYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          117 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 cctcctccct gtccgcatct gtaggagacg cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taatttaaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataagac atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ccgtggacgt tcggccaagg ggccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005780             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13064:13124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005780
VERSION     KCVT01005780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13064:13124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83305.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgacgat ggaaacacct atttggattg gtacctacag aaaccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctcgggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gaggctgagg
      361 atgttggcgt ttattattgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005781             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19615:9680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005781
VERSION     KCVT01005781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19615:9680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83306.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcag ctgagaccag ggaaagcccc gaaggcctta
      241 atctattacg cgaccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aggattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005782             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9537:18810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005782
VERSION     KCVT01005782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9537:18810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83307.1"
                     /translation="CQQHNTSPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c          109 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccattact tgcagagcca gtcaggatat
      181 tagcgactgg ttggcctggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttgcaaa caggggcccc atcaaggttc agtggaggtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcataat acttccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005783             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16729:15672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005783
VERSION     KCVT01005783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16729:15672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83308.1"
                     /translation="CMQTLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccgggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005784             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16695:19358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005784
VERSION     KCVT01005784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16695:19358"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83309.1"
                     /translation="CLQGDTAPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          114 c          114 g           95 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggcaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattaa cgattattta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcattcagt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcagcttatt
      361 actgtctaca gggtgatact gccccgttca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005785             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:26649:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005785
VERSION     KCVT01005785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:26649:10474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83310.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cattgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005786             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22453:16469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005786
VERSION     KCVT01005786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22453:16469"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83311.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaagt ttccaatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005787             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14714:5049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005787
VERSION     KCVT01005787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14714:5049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83312.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggggcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005788             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10455:6935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005788
VERSION     KCVT01005788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10455:6935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83313.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          118 c          119 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagagacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagt agggccaccg gcgtcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005789             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12635:17104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005789
VERSION     KCVT01005789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12635:17104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83314.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          125 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttcca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cgcagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005790             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14861:9097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005790
VERSION     KCVT01005790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14861:9097"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83315.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005791             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16831:12789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005791
VERSION     KCVT01005791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16831:12789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83316.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagcctggt atcaacagag accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01005792             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18228:6962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005792
VERSION     KCVT01005792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18228:6962"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83317.1"
                     /translation="CQQGYNTPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          113 g           88 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcagggtat
      181 tagcagctgg ttagcctggt atcagcagaa accagggaaa gcccctagac tcctgatcta
      241 taaggcgtcc actttggcaa gtggggtccc atcaaccttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcaggctgga gcctgaagat tttgcaactt attattgtca
      361 acagggttac aataccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005793             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22428:19547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005793
VERSION     KCVT01005793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22428:19547"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83318.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagtca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac tcgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01005794             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25534:7746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005794
VERSION     KCVT01005794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25534:7746"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83319.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgacg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005795             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:7191:18686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005795
VERSION     KCVT01005795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7191:18686"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..391
                     /note="immunoglobulin light chain variable region"
     V_region        70..391
     V_segment       70..344
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83320.1"
                     /translation="CQQHNGYPPTF"
     J_segment       357..391
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT           98 a          110 c           98 g           88 t
ORIGIN      
        1 acatgggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg gctcccaggt
       61 gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac
      121 acagtcacca tcacttgtcg ggcaagtcag ggcattacga atgatttagc ctggtatgaa
      181 cagaaaccag gtaaagcccc gaagcccctg atctattacg catccaattt ggaaagtggg
      241 gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac catcagcagc
      301 ctgcagcctg aagattttgc aacttattat tgtcaacagc ataatggata ccctccgacg
      361 ttcggccaag tgaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01005796             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11789:9440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005796
VERSION     KCVT01005796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11789:9440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83321.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005797             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13960:2316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005797
VERSION     KCVT01005797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13960:2316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83322.1"
                     /translation="CQHSYDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          116 c          104 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagcccctg agctcctgat
      241 ttatgttaca tccactttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcatagt tatgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005798             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14216:17148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005798
VERSION     KCVT01005798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14216:17148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..382
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83323.1"
                     /translation="CYQHSRGWAF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          122 c          116 g           84 t
ORIGIN      
        1 acatggggag agctgctagg ttagtaccca gaaggaacca tggaagcccc agctcagctt
       61 ctctgccttc tgctactctg gctcccaggt accaccggac aaattatatt gacacagtct
      121 ccagccaccc tgtctttggc accaggggaa agagccactc tctcctgcag ggccagtgag
      181 aatgttggca gctacttagc ctggtaccag cagaaccctg ggcaggctcc caggctcctc
      241 gtccacagtg cgtccagcag ggccactgac atcccataca ggttcagtgg cagtgggtct
      301 cggacagagt tcaccctcac catcagcagt ctggagcctg aagatgttgg agtctattac
      361 tgctatcaac atagcagggg gtgggcgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01005799             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:3840:17874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005799
VERSION     KCVT01005799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3840:17874"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83324.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcacattc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005800             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12560:5363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005800
VERSION     KCVT01005800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12560:5363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83325.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          104 a          125 c          122 g           87 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag
      121 tgatgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagcg tagcctggta ccagcagaaa cctgggcagg
      241 ctcccagact cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca
      301 gtggcagtgg gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg
      361 ttgcacttta ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01005801             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18885:13224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005801
VERSION     KCVT01005801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18885:13224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83326.1"
                     /translation="CQHGYGIQLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          116 c          112 g           96 t
ORIGIN      
        1 acatggggga gtcagtccca gtcaggacac agcatggaca tgagggcccc cactcagctc
       61 ctggggttcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac agagtcacca tctcttgcca ggcgagtcag
      181 gacattagca atgatttagc ctggtatcag cagaaaccgg gaaaagcccc taggctcctg
      241 atgtataagg catccgcttt gcagattggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcaacagc ctgcagcctg aagattttgc aacttactac
      361 tgtcaacatg gttatggtat ccagctcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01005802             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15917:7430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005802
VERSION     KCVT01005802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15917:7430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..380
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83327.1"
                     /translation="CYQHSRGWAF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g           83 t
ORIGIN      
        1 acatggggag ctgctaggtt agtacccaga aggaaccatg gaagccccag ctcagcttct
       61 ctgccttctg ctactctggc tcccaggtac caccggacaa attatattga cacagtctcc
      121 agccaccctg tctttggcac caggggaaag agccactctc tcctgcaggg ccagtgagaa
      181 tgttggcagc tacttagcct ggtaccagca gaaccctggg caggctccca ggctcctcgt
      241 ccacagtgcg tccagcaggg ccactgacat cccagacagg ttcagtggca gtgggtctcg
      301 gacagagttc accctcacca tcagcagtct ggagcctgaa gatgttggag tctattactg
      361 ctatcaacat agcagggggt gggcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005803             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9688:17094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005803
VERSION     KCVT01005803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9688:17094"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83328.1"
                     /translation="CLQGYITPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          113 c          109 g           99 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg gcttattact
      361 gtctacaggg ttatattacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005804             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24276:6371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005804
VERSION     KCVT01005804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24276:6371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83329.1"
                     /translation="CQQHDNMPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          114 c          116 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc ggtctgcatc tgtgggagac agagtcacca tcacttgcag ggccagtcag
      181 ggtattagca actggttggc ctggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctataggg catggaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatcc
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgataatat gccgctcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01005805             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:23664:10281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005805
VERSION     KCVT01005805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23664:10281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83330.1"
                     /translation="CQQYNSEPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           89 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcccgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgagccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005806             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22009:9689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005806
VERSION     KCVT01005806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22009:9689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83331.1"
                     /translation="CQQYNSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          113 c          106 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagcagaa accaggaaaa gccccgaagg ccttgatcta
      241 ttacgcatcc attttagaga gtgcggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gtctgacgat tttgcaactt attactgtca
      361 acagtataac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005807             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19135:13949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005807
VERSION     KCVT01005807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19135:13949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83332.1"
                     /translation="CQQYNSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatcg gcaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattagcag ttatttagct tggtatcggc agaagccagg gaaagccccg gagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca actttttact
      361 gtcaacagta taacagtgac tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005808             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18545:9687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005808
VERSION     KCVT01005808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18545:9687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..415
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <393..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83333.1"
                     /translation="CLQSKNSPWSF"
     J_segment       416..453
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>456
                     /gene="IGKC"
BASE COUNT          104 a          122 c          127 g          103 t
ORIGIN      
        1 acatggggag gcagcttgtc aggggccctg aggagcagcc tctagttcag ctctcagaaa
       61 tggggtcctg ggctcctttc ctgtggatcc tcctgctctg tgctccaggc tgcagtgggg
      121 acattgtgct gacccagtct ccagcctctt tggccgtgtc tccagggcag agggccacca
      181 tcacctgcag agccagtgag agtgtcagtg cctttggaat aagcctcatt cactggtatc
      241 aacagaaacc aggacaacct cctaaactcc tgatttacca agcaatcaat aaggagactg
      301 gggtcccagc caggttcagc ggcagtgggt ctgggaccga tttcaccctc acaattaatc
      361 ctgtggaacc tgacgatggt gcagattatt actgtctgca gagtaagaat tctccgtggt
      421 cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01005809             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14991:7429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005809
VERSION     KCVT01005809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14991:7429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83334.1"
                     /translation="CQQYNSFPFTF"
     J_segment       386..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          122 c          104 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcagggca cagcatgggc atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacagccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattatc agttatttaa attggtatca acacaaaccg gggaaagccc ctacgctcct
      241 ggtctattat ggaaaccgtt tacacagtgg ggtcccatca cggttcagcg ccagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaggattttg caacttattt
      361 ctgtcaacag tataatagtt tccctttcac tttcggcccc gggaccaaac tggatttcaa
      421 acgag
//
LOCUS       KCVT01005810             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18118:20025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005810
VERSION     KCVT01005810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18118:20025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83335.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          117 c          110 g           90 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattagcaa ctggttggtc tggtatcaac agagaccagg gaaagcccct aaggtcctga
      241 tttataggac atccaatttg gaaacagggg tcccatcaag gttcagtgga accggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgct acatattact
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005811             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:28468:10749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005811
VERSION     KCVT01005811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:28468:10749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83336.1"
                     /translation="CQQYNSDPYSF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          110 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaattgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagga attatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattaca catccatttt ggaaaatggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcagtctcac catcagcagc ctgcaggctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccatacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005812             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20319:2781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005812
VERSION     KCVT01005812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20319:2781"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83337.1"
                     /translation="CQQHNTYPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           92 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcactag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaagcccc
      241 tgatctttta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataatact tacccgtaca cttttggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005813             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14553:7452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005813
VERSION     KCVT01005813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14553:7452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83338.1"
                     /translation="CQHSFRTPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          116 c          109 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaatgtc acttgcaggg ctagtgagag
      181 cgttagcacc aaattacatt ggtatcagca gaaaccaggg aaagccccta agctcctgat
      241 ctttgctgcg tccactttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 aacagatttc actctcacca tcagcagcct gcagcctgaa gatgtcgcaa ctttttactg
      361 tcagcatagt tttcgtaccc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005814             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16508:15387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005814
VERSION     KCVT01005814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16508:15387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83339.1"
                     /translation="CMQALEFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          122 g          103 t
ORIGIN      
        1 acatgggggg gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggag tggcacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgacgt ttccagccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccctacagtt ttggccaggg
      421 gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01005815             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6866:15594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005815
VERSION     KCVT01005815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6866:15594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83340.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          118 c          105 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat aattactctc ccactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005816             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12696:20760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005816
VERSION     KCVT01005816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12696:20760"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83341.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          123 c          112 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc aaaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag attcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005817             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21213:4566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005817
VERSION     KCVT01005817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21213:4566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83342.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          121 c          122 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005818             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11073:9536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005818
VERSION     KCVT01005818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11073:9536"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83343.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          117 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggatatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005819             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13788:10212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005819
VERSION     KCVT01005819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13788:10212"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83344.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          117 g          110 t
ORIGIN      
        1 actgggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct tgagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005820             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16844:16099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005820
VERSION     KCVT01005820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16844:16099"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..396
                     /note="immunoglobulin light chain variable region"
     V_region        75..396
     V_segment       75..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83345.1"
                     /translation="CQQYDSDSLTF"
     J_segment       359..396
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>399
                     /gene="IGKC"
BASE COUNT           96 a          108 c          103 g           92 t
ORIGIN      
        1 acatggggat ggacatgagg gtccccgctc agctcctagg actcctgctg ctctgtctcc
       61 caggtgccaa atgtgacatc cagatgaccc agtctccatc ctccctgtct gcatctgtag
      121 gagacagagt caccatcact tgtcgggcga ctcaggacat tcgcagttat ttagcgtggt
      181 atcagcagaa accagggaaa gccccgaagc ccttgatcta ttacgcgtcc actttggaaa
      241 gtggggtccc atcaaggttc agcggcagtg gatctgggac agaattcact ctcaccatca
      301 gcagcctgca gcctgaagat tttgcaactt attactgtca acagtatgac agtgattcgc
      361 tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005821             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:27149:10801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005821
VERSION     KCVT01005821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27149:10801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83346.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccattttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005822             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:8411:15593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005822
VERSION     KCVT01005822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:8411:15593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83347.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgtttg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005823             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10906:8564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005823
VERSION     KCVT01005823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10906:8564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83348.1"
                     /translation="CMQSLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctctag agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005824             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19873:4379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005824
VERSION     KCVT01005824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19873:4379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83349.1"
                     /translation="CMQGLQTPYTF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          119 c          119 g          106 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcac cttgtcacaa tgaggctccc tgctcagctc
       61 ctggggctgc taatgctctg ggtctctgcc tccagtggag atatcgtgat gacccagact
      121 ccactctcgc tgcccgtcac ccttggagag ccagcctcca tctcctgcag gtctagtcag
      181 agccttctga atagtaatgg atacagctat ttgagttggt acctgcagag gccaggccag
      241 tctccacatc tgctgatcta ttatggctct agtcgggcct ccggggtccc cgacaggttc
      301 agtggcagtg ggtcaggcac agattttaca ctgaaaatca ccagggtgga ggttgacgac
      361 gtaggggttt attactgcat gcaaggtcta caaactccgt acacttttgg ccaggggacc
      421 aaagtggaga tcaaacgag
//
LOCUS       KCVT01005825             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:8911:9751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005825
VERSION     KCVT01005825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8911:9751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83350.1"
                     /translation="CQQYHSTPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          103 a          115 c          122 g           99 t
ORIGIN      
        1 acatgggggc tacaacaggc aggcaggggc agcaagatgg tgtcacagac ccaagtcttc
       61 atttccctgt tgctctggat ctctggtgcc tgtggggaca ttgtgatgac ccagtcgcca
      121 gactccctgg ctgtgtctct gggagagagg gtcaccatca actgcaagtc cagccagagt
      181 cttttacgca tctccaacaa taggaactac ttagcctggt atcagcagaa accagggcag
      241 gctcctaaac tgctcgttta ctgggcatct acccgggaat tcgggatccc taaccgattc
      301 agtggcagtg gatctgggtc agatttcact ctcaccatca ctggcctgca ggctgaagat
      361 gtggcagtgt attactgtca gcagtatcat agcactccgt ggacgttcgg ccaagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01005826             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16366:13390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005826
VERSION     KCVT01005826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16366:13390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83351.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtcaagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttgcact ggtacttgaa gaagccaggc
      241 cagtctccac agctcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005827             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8659:16838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005827
VERSION     KCVT01005827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8659:16838"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    21..342
                     /note="immunoglobulin light chain variable region"
     V_region        21..342
     V_segment       21..300
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <282..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83352.1"
                     /translation="CQQYDSDSLTF"
     J_segment       305..342
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>345
                     /gene="IGKC"
BASE COUNT           90 a           88 c           88 g           79 t
ORIGIN      
        1 acatgggagg tgccaaatgt gacatccaga tgacccagtc tccatcctcc ctgtctgcat
       61 ctgtaggaga cagagtcacc atcacttgtc gggcgactca ggacattcgc agttatttag
      121 cgtggtatca acagaaacca gggaaagccc cgaggccctt gatctattac gcgtccactt
      181 tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca
      241 ccatcagcag cctgcagcct gaagattttg caacttatta ctgtcaacaa tatgacagtg
      301 attcgctcac tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01005828             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19636:20832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005828
VERSION     KCVT01005828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19636:20832"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83353.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          122 c          122 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01005829             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:8361:6659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005829
VERSION     KCVT01005829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8361:6659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83354.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          118 c          108 g           92 t
ORIGIN      
        1 atggggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagtc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005830             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17803:10438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005830
VERSION     KCVT01005830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17803:10438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83355.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcgtccat ctcctgcagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01005831             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19703:10492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005831
VERSION     KCVT01005831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19703:10492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83356.1"
                     /translation="CMQARDFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          125 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cattggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggaag gaaacaccta tttggagtgg tacctgcaga ggccaggcca
      241 gtctccacag gtcttgattt atggggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgagaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agactttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01005832             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12450:7775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005832
VERSION     KCVT01005832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12450:7775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83357.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          117 c          125 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggg
      241 cagtctccac aactcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aagtcaaacg ag
//
LOCUS       KCVT01005833             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22031:10286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005833
VERSION     KCVT01005833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22031:10286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83358.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01005834             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14103:10492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005834
VERSION     KCVT01005834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14103:10492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83359.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          113 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005835             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:5710:17998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005835
VERSION     KCVT01005835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5710:17998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83360.1"
                     /translation="CQQYYSTPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          105 a          113 c          121 g          100 t
ORIGIN      
        1 acatgggggc tacaacaggc aggcaggggc agcaagatgg tgtcacagac ccaagtcttc
       61 atttccctgt tgctctggat ctctggtgcc tgtggggaca ttgtgatgac ccagtcgcca
      121 gactccctgg ctgtgtctct gggagagagg gtcaccatca actgcaagtc cagccagagt
      181 cttttacgca tctccaacaa taggaactac ttagcctggt atcagcagaa accagggcag
      241 gctcctaaac tgctcattta ctgggcatct acccgggaat tcgggatccc taaccgattc
      301 agtggcagtg gatctgggtc agatttcact ctcaccatca gtggcctgca ggctgaagat
      361 gtggcagtgt attactgtca gcagtattat agcactccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005836             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11976:16903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005836
VERSION     KCVT01005836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11976:16903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83361.1"
                     /translation="CMQSLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg agattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg ccagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005837             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21698:13417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005837
VERSION     KCVT01005837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21698:13417"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    214..368
                     /note="immunoglobulin light chain variable region"
     V_region        214..368
     V_segment       214..330
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83362.1"
                     /translation="CMQPLEFPWTF"
     J_segment       331..368
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           79 a          101 c          105 g           86 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccggtctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtc ccagacaggt tcagtggcag
      241 tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt
      301 ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga ccaaggtgga
      361 aatcaaacga g
//
LOCUS       KCVT01005838             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:25625:12268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005838
VERSION     KCVT01005838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25625:12268"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..421
                     /note="immunoglobulin light chain variable region"
     V_region        82..421
     V_segment       82..383
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83363.1"
                     /translation="CMQPLEFPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           92 a          116 c          116 g          100 t
ORIGIN      
        1 acatggggtc accttctcac aatgaggctc cctgctcagc tcctgggact gctaatgctc
       61 tggctccctg gatccagtgg ggacattgtg ctgacccaga ctccactctc cctgcccgtc
      121 acccttggag agccggcctc catctcctgc aggtctagtc agagcctctt ggatagtgag
      181 gatggaaaca cctatttgga atggtacctc cagaagccag gccagtctcc acatctcttg
      241 atttatgagg tttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca
      301 gacactgatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg ggtttattac
      361 tgcatgcaac ctctagagtt tccgtggacg ttcggccagg ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005839             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15530:12672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005839
VERSION     KCVT01005839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15530:12672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..409
                     /note="immunoglobulin light chain variable region"
     V_region        96..409
     V_segment       96..379
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83364.1"
                     /translation="CLQGDCTPFTF"
     J_segment       386..409
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>420
                     /gene="IGKC"
BASE COUNT          100 a          114 c          111 g           95 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cttccctgtc tgcatcggta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcgatta tttaagttgg tatcagcaga aaccgggaaa agctcctaag cgcctaatct
      241 atgctgcatc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagagttcac tctcaccatc agcagcctgc agcctgaaga ttttgcgact tattactgtc
      361 tacagggtga ttgtaccccg ttcacttttg gccaggggac caaagtggac gtcaaacgag
//
LOCUS       KCVT01005840             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24219:9233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005840
VERSION     KCVT01005840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24219:9233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83365.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gtctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005841             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21913:12584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005841
VERSION     KCVT01005841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21913:12584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83366.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgatggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005842             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:25036:14409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005842
VERSION     KCVT01005842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25036:14409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83367.1"
                     /translation="CQQYDSDSLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          121 c          117 g           99 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt attgtcaaca gtatgacagt gattcgctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01005843             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:4664:10531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005843
VERSION     KCVT01005843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4664:10531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83368.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          116 c          111 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 aggatattaa caactggttg gcctggtatc aacagaaacc agggaaagcc cctaaggtcc
      241 tgatctatag ggcatccatt ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005844             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:25503:11637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005844
VERSION     KCVT01005844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25503:11637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83369.1"
                     /translation="CMQALDFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          127 c          114 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 cccccctccc tgcccgtcac ccttggagag gcggcctcca tctcctgtag gtctagtcag
      181 agcctcttcg atactgaaga aggaaacacc tatttggagt ggtacctgca gaggccaggc
      241 cagactccac agctcttgat ttatcaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggac tttattactg catgcaggct ctagactttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01005845             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21751:11684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005845
VERSION     KCVT01005845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21751:11684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83370.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggtcactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005846             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8925:18185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005846
VERSION     KCVT01005846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8925:18185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..415
                     /note="immunoglobulin light chain variable region"
     V_region        76..415
     V_segment       76..377
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83371.1"
                     /translation="CMQALEFPLTF"
     J_segment       378..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           91 a          110 c          116 g          101 t
ORIGIN      
        1 atgggccttc tcacaatgag gctccctgct cagctcctgg gactgctaat gctctggctc
       61 cctggatcca gtggggacat tgtgatgacc cagagtccac tctccctgtc cgtcaccctt
      121 ggagagccgg cctccatctc ctgcaggtct agtcagagcc tcttggatag tgaggatgga
      181 aacacctatt tggaatggta cctgcagaag ccaggccagt ctccacagct cttgatttat
      241 gagatttcca accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact
      301 gatttcacac tgaaaatcag cacagtggag gctgaggatg ttggggttta ttactgcatg
      361 caagctctag agtttccgct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01005847             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20206:14483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005847
VERSION     KCVT01005847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20206:14483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83372.1"
                     /translation="CLQYKSYPLTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>420
                     /gene="IGKC"
BASE COUNT          106 a          112 c          104 g           98 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatcac ttgccgggca agtcaggata
      181 ttagcactta tttaaattgg tttcagcaga aaccagggaa agcccctaga ctcctgatct
      241 atgctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tatcactgtc
      361 tacagtataa aagttaccct ctcactttcg gcggagggac caaggtggag atcaaaagag
//
LOCUS       KCVT01005848             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17064:7945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005848
VERSION     KCVT01005848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17064:7945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..311
                     /note="immunoglobulin light chain variable region"
     V_region        6..311
     V_segment       6..273
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83373.1"
                     /translation="CEQYNSLPYTF"
     J_segment       274..311
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>314
                     /gene="IGKC"
BASE COUNT           90 a           76 c           71 g           77 t
ORIGIN      
        1 atgggagtct ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg
       61 ggcaagtcag gacattaaca tttatttaaa ttggtatcac cagaaaccgg ggaaagcccc
      121 taagctcctg atctattata caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg
      181 cagtggatct gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc
      241 aacttattac tgtgaacaat acaatagttt accgtacact tttggccagg ggaccaaagt
      301 ggagatcaaa cgag
//
LOCUS       KCVT01005849             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18618:10668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005849
VERSION     KCVT01005849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18618:10668"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83374.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacctatta
      361 ctgtcaacag tatgacagtg atccgttcac tttcggtggg gggaccaagg tagacatcaa
      421 acgag
//
LOCUS       KCVT01005850             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17752:10005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005850
VERSION     KCVT01005850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17752:10005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83375.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcgatgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005851             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21138:9676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005851
VERSION     KCVT01005851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21138:9676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83376.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcacca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005852             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8997:16920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005852
VERSION     KCVT01005852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8997:16920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83377.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaacgt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005853             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:26326:4371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005853
VERSION     KCVT01005853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:26326:4371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    59..380
                     /note="immunoglobulin light chain variable region"
     V_region        59..380
     V_segment       59..343
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <320..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83378.1"
                     /translation="CQQDFDWPPTF"
     J_segment       346..380
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>383
                     /gene="IGKC"
BASE COUNT           88 a          116 c           99 g           80 t
ORIGIN      
        1 acatggggca gcacagcttc tcttcctcct gctactctgg atcccagata ccaccggaga
       61 agttgtgatg acgcagtctc cagccaccct gtctttgtct ccaggggaaa gagccaccct
      121 ctcctgcagg gccagtcaga gtgttggcaa caccttaacc tggtaccagc acaaacctgg
      181 gcaggctccc aagctcctcg tctatggtgc atccaccagg gccaccggca tcccagacag
      241 gttcagtgcc agtgggtccg gaacagagtt tactctcacc atcagcagcc tggagcctga
      301 agatgttgga atttattact gtcagcagga ttttgactgg cctccgacgt tcggccaagg
      361 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005854             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20656:3210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005854
VERSION     KCVT01005854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20656:3210"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83379.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          116 c          114 g           93 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01005855             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:25915:4817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005855
VERSION     KCVT01005855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25915:4817"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83380.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca ttttctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccgaccggg cctctggagt cccagccagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005856             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21889:7139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005856
VERSION     KCVT01005856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21889:7139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83381.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggccttcat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005857             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12994:10259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005857
VERSION     KCVT01005857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12994:10259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..411
                     /note="immunoglobulin light chain variable region"
     V_region        101..411
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83382.1"
                     /translation="CLQGDTTPFTF"
     J_segment       391..411
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>425
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           97 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggatattagc gattatttaa gttggtatca gcagaaaccg ggaaaagctc ctaagcgcct
      241 aatctatgct gcctccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgagacagtg ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtctacag ggtgatacta ccccgttcac ttttggccag gggaccaaag tagacgtcaa
      421 acgag
//
LOCUS       KCVT01005858             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14454:7672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005858
VERSION     KCVT01005858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14454:7672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..341
                     /note="immunoglobulin light chain variable region"
     V_region        20..341
     V_segment       20..303
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83383.1"
                     /translation="CQQYDSDPFTF"
     J_segment       306..341
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           88 a           87 c           90 g           79 t
ORIGIN      
        1 acatgggggt gccaaatgtg acatccagat gacccagtct ccatccttcc tgtctgcatc
       61 tgtaggagac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca gttatttagc
      121 gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg cgtccacttt
      181 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      241 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt atgacagtga
      301 cccgttcact ttcggtggag ggaccaaggt agagatcaaa cgag
//
LOCUS       KCVT01005859             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7248:16018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005859
VERSION     KCVT01005859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7248:16018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83384.1"
                     /translation="CQQYNSDWRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          113 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga ctggcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005860             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9171:15882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005860
VERSION     KCVT01005860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9171:15882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83385.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          124 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagtcaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005861             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:16125:10170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005861
VERSION     KCVT01005861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16125:10170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83386.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gtcggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa ataagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005862             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11578:6069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005862
VERSION     KCVT01005862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11578:6069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83387.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgcgc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005863             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11356:2894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005863
VERSION     KCVT01005863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11356:2894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..383
                     /note="immunoglobulin light chain variable region"
     V_region        110..383
     V_segment       110..345
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83388.1"
                     /translation="CHQYNNLPLTF"
     J_segment       347..383
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT          103 a          102 c           95 g           86 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtcac
      121 catcacttgc cgggcaagtc aggacattaa catttattta aattggtatc agcagaaacc
      181 ggggaaagcc cctaagctcc tgatctatta tgcaaatcgt ttggaaactg gggtcccgtc
      241 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcaaca gcctgcaacc
      301 cgaagatttt gcaacttatt actgtcacca gtataataat ttaccactca ctttcggcgg
      361 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01005864             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:6611:9837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005864
VERSION     KCVT01005864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:6611:9837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83389.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aaaccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttattactgc atgcaagctc tagagtttcc tctcactttc ggcgagggac
      421 caaggtggag gtcaaacgag
//
LOCUS       KCVT01005865             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14373:17187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005865
VERSION     KCVT01005865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14373:17187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83390.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atatggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005866             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8547:10491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005866
VERSION     KCVT01005866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8547:10491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83391.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          104 a          124 c          123 g           87 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag
      121 tgatgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagcg tagcctggta ccagcagaaa cctgggcagg
      241 ctcccagact cctcatgtat ggtgcatcca acagggccac tggcatccca gacaggttca
      301 gtggcagtgg gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg
      361 ttgcacttta ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01005867             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12422:18150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005867
VERSION     KCVT01005867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12422:18150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..442
                     /note="immunoglobulin light chain variable region"
     V_region        100..442
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83392.1"
                     /translation="CMQALEFPPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          123 c          116 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagaat
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattattg catgcaagct ctagagtttc ctccattcac tttcggcccc
      421 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01005868             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:24430:10074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005868
VERSION     KCVT01005868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:24430:10074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83393.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          125 c          121 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtttccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc aggctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 agtggagatc aaacgag
//
LOCUS       KCVT01005869             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19411:7352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005869
VERSION     KCVT01005869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19411:7352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83394.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005870             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17976:14563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005870
VERSION     KCVT01005870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17976:14563"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83395.1"
                     /translation="CLQYKSYPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          111 c          106 g           98 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 ggatatttac agttatttga attggtttca gaagaaacca gggaaagccc ctaagctcct
      241 gatccaagct gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcaacag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag tataaaagtt acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01005871             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18442:5602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005871
VERSION     KCVT01005871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18442:5602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83396.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          124 c          111 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg aaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01005872             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:25169:14236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005872
VERSION     KCVT01005872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25169:14236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83397.1"
                     /translation="CQHSHGSPITF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgtttac aactatttac attggtatca gcagaaacca gggaaagccc ctaaggtcct
      241 gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggactgat ttcactctca ccatcagcag cccgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005873             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14261:8620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005873
VERSION     KCVT01005873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14261:8620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83398.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005874             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:28835:13688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005874
VERSION     KCVT01005874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:28835:13688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83399.1"
                     /translation="CQQYNSLPLTF"
     J_segment       387..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          109 a          110 c          110 g           98 t
ORIGIN      
        1 acatgggagg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctcagct ctggctccca ggtgccagat gtgacattca gatgacccag
      121 tctccatcct ccctgtctgc atctctgggg gacagagtca ccatcacttg ccgggcaagt
      181 caggacatta gcagatattt aaattggtat cagcagaaac cggggaaagc ccctaagttc
      241 ctgatctatt atgtaaaccg tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcaac ctgaagattt tgcaacttat
      361 tattgtcaac agtataatag tttaccgctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01005875             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:13752:7939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005875
VERSION     KCVT01005875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13752:7939"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..399
                     /note="immunoglobulin light chain variable region"
     V_region        80..399
     V_segment       80..363
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83400.1"
                     /translation="CLQYKSYPLTF"
     J_segment       364..399
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>403
                     /gene="IGKC"
BASE COUNT           99 a          108 c           99 g           97 t
ORIGIN      
        1 acatggggac agcatggaca tgagggcccc cgctcatctc ctagggctct tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gactcagtct ccatcttccc tgtctgcatc
      121 tgtaggagac actgtcacca tcacttgccg ggcaagtcag ggtattagca cttatttaaa
      181 ttggtttcag cagaaaccag ggaaagcccc tagactcctg atctatgctg catccagttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacaaatt cactctcacc
      301 atcagcagcc tgcagcctga agattttgca gcttatcact gtctacagta taaaagttac
      361 cctctcactt tcggcgaagg gaccaaggtg gagatcaaaa gag
//
LOCUS       KCVT01005876             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18418:9535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005876
VERSION     KCVT01005876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18418:9535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..396
                     /note="immunoglobulin light chain variable region"
     V_region        75..396
     V_segment       75..359
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83401.1"
                     /translation="CQQHDDSPRTF"
     J_segment       361..396
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>399
                     /gene="IGKC"
BASE COUNT          102 a          110 c          102 g           85 t
ORIGIN      
        1 acatgggcat ggacacgagg gtccccgctc agctcctggg gctcctgttg ctctggctcc
       61 caggtgccag atgtgacatc cagatgaccc agtctccatc ctccctgtct gcatctgtag
      121 gagacagagt caccatcact tgcagagcca gtcaggatat taacaactgg ttggcctggt
      181 atcaacagaa accagggaaa gcccctaagg tcctgatcta tagggcatcc attttggaaa
      241 caggggtccc atcaaggttc agtggaagtg gatctgggac agatttcact ctcaccatca
      301 gcagcctgca gcctgaagat atcgcaacat attactgtca acagcatgat gattcccctc
      361 ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005877             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14123:6085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005877
VERSION     KCVT01005877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14123:6085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83402.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cgctctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tccctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005878             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9334:12288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005878
VERSION     KCVT01005878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9334:12288"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83403.1"
                     /translation="CQQYNSLPYIF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          110 a          109 c          102 g           97 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 aacgtttatt taaattggta tcagcagaaa ccggggaaag cccctaaacc cctgatctat
      241 tatagaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataata gtttaccgta catttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01005879             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13191:7824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005879
VERSION     KCVT01005879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13191:7824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83404.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggccttcat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01005880             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12372:8795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005880
VERSION     KCVT01005880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12372:8795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83405.1"
                     /translation="CLQYNSNPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          115 c          106 g           95 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg caggggacag agtcaccatc acttgcaggg caagtcaggg
      181 cattaccact tatttaaatt ggtatcagca taaaccagga aaacctccta agcgcctgat
      241 ctatggtgca tacagtttgg gaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagtagcct gcagcctgaa gattttgcaa cttattactg
      361 tctacagtat aatagtaacc ctccgacgtt cggccaaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005881             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20324:4899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005881
VERSION     KCVT01005881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20324:4899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83406.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005882             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8787:6790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005882
VERSION     KCVT01005882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8787:6790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83407.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          121 c          119 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcctgg atagtgagga tggaaacacc tatttgcact ggtacctgaa gaagccaggc
      241 cagtctccac agctcttaat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005883             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:3115:19285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005883
VERSION     KCVT01005883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3115:19285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..387
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83408.1"
                     /translation="CLQSKNSPWSF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          115 c          114 g           99 t
ORIGIN      
        1 acatggggag cctctagttc agctctcaga aatggggtcc tgggctcctt tcctgtggat
       61 cctcctgctc tgtgctccag gctgcagtgg ggacattgtg ctgacccagt ctccagcctc
      121 tttggccgtg tctccagggc agagggccac catcacctgc agagccagtg agagtgtcag
      181 tgcctttgga ataagcctca ttcactggta tcaacagaaa ccaggacaac ctcctaaact
      241 cctgatttac caagcaatca ataaggagac tggggtccca gccaggttca gcgacagtgg
      301 gtctgggacc gatttcaccc tcacaattaa tcctgtggaa cctgacgatg gtgcagatta
      361 ttactgtctg cagagtaaga attctccgtg gtcgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01005884             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20416:5864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005884
VERSION     KCVT01005884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20416:5864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..425
                     /note="immunoglobulin light chain variable region"
     V_region        86..425
     V_segment       86..388
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83409.1"
                     /translation="CMQSLEIPPTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           92 a          114 c          120 g          102 t
ORIGIN      
        1 acatggggga ggtcaccttc tcacaatgag gctccctgct cagctcctgg gactgctaat
       61 gctctggctc cctggatcca gtggggacat tgtgatgacc cagactccac tctccctgcc
      121 cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagcc tcttggatag
      181 tggggatgga aacacctatt tggattggta cctgcagaag ccaggccagt ctccacagct
      241 cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg
      301 gtcagacact gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta
      361 ttactgcatg caatctctag agattcctcc cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01005885             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10574:19012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005885
VERSION     KCVT01005885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10574:19012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83410.1"
                     /translation="CQRYSYSTWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          120 c          115 g           91 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttgg tttggtacca gcagaaacct gggcaggccc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtatatta
      361 ctgtcagagg tatagttact ccacgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01005886             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:3287:14835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005886
VERSION     KCVT01005886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3287:14835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83411.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          125 c          109 g           85 t
ORIGIN      
        1 acatgggaga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcaa cagcttagcc tggtaccaac aaaaacctgg gcagcctccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagaggc agtgggtctg
      301 ggacagactt cactctcacc atcaccagcc tggagcctga agatgttgca gtttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005887             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19802:11902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005887
VERSION     KCVT01005887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19802:11902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..409
                     /note="immunoglobulin light chain variable region"
     V_region        128..409
     V_segment       128..371
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83412.1"
                     /translation="CMQPLEFPWTF"
     J_segment       372..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           95 a          105 c          113 g           99 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacact
      181 tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt
      241 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      301 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaacct
      361 ctagagtttc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005888             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13033:7741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005888
VERSION     KCVT01005888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13033:7741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83413.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctatggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005889             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20762:18439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005889
VERSION     KCVT01005889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20762:18439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83414.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005890             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19312:19165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005890
VERSION     KCVT01005890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19312:19165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..383
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83415.1"
                     /translation="CQQYDDYPWTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac aaagtcacca tcacttgcca tgccagtcag
      181 ggtattagta gtcggttagt ctggtatcag cagaaaccag ggaaagcccc taagcccctg
      241 atgtatgctg catccagttt acacagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgatgatta cccgtggacg ttcggccaag ggaccaaggt ggaaatcaag
      421 cgag
//
LOCUS       KCVT01005891             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10864:18585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005891
VERSION     KCVT01005891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10864:18585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..382
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83416.1"
                     /translation="CYQHSRGWAF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           97 a          124 c          116 g           84 t
ORIGIN      
        1 acatggggag agctgctagg ttagtaccca gaaggaacca tggaagcccc agctcagctt
       61 ctctgccttc tgctactctg gctcccaggc accaccggac aagttatgtt gacacagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccactc tctcctgcag ggccagtgag
      181 aatgttggca tctacttagc ctggtaccag cagaaccctg ggcaggctcc caggctcctc
      241 atccacagtg cgtccagcag ggccactgac atcccagaca ggttcagtgg cagtgggtct
      301 cggacagagt tcaccctcac catcagcagc ctggagcctg aagatgttgg agtctattac
      361 tgctatcaac atagcagggg gtgggcgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01005892             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:14474:8987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005892
VERSION     KCVT01005892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14474:8987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83417.1"
                     /translation="CQQYDSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          113 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gtcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005893             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9069:14726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005893
VERSION     KCVT01005893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9069:14726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83418.1"
                     /translation="CQKYISSPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          130 c          105 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aacttatatt gactcagtct
      121 ccagccaccc tgtctctgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 ctctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtatattac
      361 tgtcagaaat atattagctc cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01005894             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9241:11699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005894
VERSION     KCVT01005894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9241:11699"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..439
                     /note="immunoglobulin light chain variable region"
     V_region        118..439
     V_segment       118..402
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83419.1"
                     /translation="CQQNSNWPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          104 a          125 c          125 g           88 t
ORIGIN      
        1 acatgggggg gtcagagctc tggggaggaa ctgctcagtt aggacccaga gggaaccatg
       61 gaagccccag cacagcttct cttcctcctg ctgctctggc tcccagatac caccggagaa
      121 atagtgatga cgcagtctcc agccaccctg tctttgtctc caggagaaag agccaccctc
      181 tcctgcaggg ccagtcagag tgtcagcagc agcgtagcct ggtaccagca gaaacctggg
      241 caggctccca gactcctcat gtatggtgca tccaacaggg ccactggcat cccagacagg
      301 ttcagtggca gtgggtctgg gacagagttc actctcacca tcagcagcct ggagcctgaa
      361 gatgttgcac tttattattg tcagcagaat agtaactggc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01005895             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21551:15889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005895
VERSION     KCVT01005895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21551:15889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83420.1"
                     /translation="CQQSYRYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atgtatctta catccacttt gcagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagatgctgc aacttattac
      361 tgtcagcaga gttatcgtta tccgctcact ttcggtggag ggacccaggt ggaaatcaat
      421 cgag
//
LOCUS       KCVT01005896             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:25571:11688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005896
VERSION     KCVT01005896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25571:11688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83421.1"
                     /translation="CHQHNSFPYSF"
     J_segment       387..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          106 a          114 c          113 g           94 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gaaacagtca ccgtcacttg tcgggcaagt
      181 cggggcgtta gtaatgattt agcctggtat cagcagaaac cagggaaagc cccgaggccc
      241 ctgatctatt atgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag atttcactct cacaatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcacc aacataatag tttcccgtac agttttggcc aggggaccaa agtggagatc
      421 aaacgag
//
LOCUS       KCVT01005897             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19569:6423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005897
VERSION     KCVT01005897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19569:6423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83422.1"
                     /translation="CQQYDSDLFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          114 c          111 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatttg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc tgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005898             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8211:11598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005898
VERSION     KCVT01005898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8211:11598"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83423.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          112 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccaggt gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagaa gttatttagc atggtatcaa ctgagaccag ggaaagcccc gaaggcctta
      241 atctattacg cgaccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcttg aggattttgc aacttatttc
      361 tgtcaacagt ataacagtga cccgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005899             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17941:8103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005899
VERSION     KCVT01005899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17941:8103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83424.1"
                     /translation="CQQGNGLPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          108 c          108 g          104 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcgtccctg tctgcttttg taggagacag agtcaccatc agttgccggg caagtcaggc
      181 cattagtagt tctttatatt ggtatcagca gaaaccgggg aaagccccta aacttctgat
      241 ttataaggca tatcttttgg aagatggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacta tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagggt aatggtttac cattcacttt cggccccggg accaaagtgg atgtcaaacg
      421 ag
//
LOCUS       KCVT01005900             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18372:18946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005900
VERSION     KCVT01005900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18372:18946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83425.1"
                     /translation="CQQYNSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          108 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa ttgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcaggacat
      181 taggaattat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttatacatcc attttggaaa atggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca ggctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01005901             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19535:4607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005901
VERSION     KCVT01005901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19535:4607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..328
                     /note="immunoglobulin light chain variable region"
     V_region        142..328
     V_segment       142..291
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83426.1"
                     /translation="CQQDFDWPPTF"
     J_segment       294..328
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>331
                     /gene="IGKC"
BASE COUNT           75 a           94 c           88 g           74 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctcctcctc tatggtgcat ccaccagggc ctccggcatc
      181 ccaggcaggt tcagtgccag tgggtctgga acagagttta ctctcaccat cagcagcctg
      241 gagcctgaag atgttggaat ttattactgt cagcaggatt ttgactggcc tccgacgttc
      301 ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005902             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:25338:12837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005902
VERSION     KCVT01005902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25338:12837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..385
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83427.1"
                     /translation="CQQHNSYPRTF"
     J_segment       387..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          106 a          117 c          110 g           92 t
ORIGIN      
        1 acatgggagg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg taccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ttgtctgcat ctgtaggaga cagagtcacc atcacttgcc aagccagtca
      181 gggtattggc aactggttag cctggtatcg gcagaaacca gggaaagccc ctaagctcct
      241 gatctatgct gcatccagtt tacaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcagcag cataatagtt atcctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 gcgag
//
LOCUS       KCVT01005903             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18112:14652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005903
VERSION     KCVT01005903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18112:14652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..400
                     /note="immunoglobulin light chain variable region"
     V_region        79..400
     V_segment       79..362
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83428.1"
                     /translation="CQQHDNSPWTF"
     J_segment       363..400
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>403
                     /gene="IGKC"
BASE COUNT          103 a          111 c          105 g           84 t
ORIGIN      
        1 acatgggaca gcatggacac gagggtcccc gctcagctcc tggggctcct gttgctctgg
       61 ctcccaggtg ccagatgtga catccagatg acccagtctc catcctccct gtctgcatct
      121 gtaggagaca gagtcaccat cacttgcaga gccagtcaga gtattaacga ctggttggcc
      181 tggtatcaac agagaccagg gaaggcccct aagctcctga tctatagggc atccaatttg
      241 gaaacagggg tcccatcaag gttcagtgga agtggatctg ggacagattt cactctcacc
      301 atcagcagcc tgcagcctga agatatcgca acatattact gtcaacagca tgataattcc
      361 ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01005904             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:22713:17183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005904
VERSION     KCVT01005904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22713:17183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83429.1"
                     /translation="CQQYDNDPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          116 c          108 g           92 t
ORIGIN      
        1 atgggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcaaca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacaatgacc cgctcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01005905             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17340:12621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005905
VERSION     KCVT01005905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17340:12621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83430.1"
                     /translation="CLQFKTYPNSF"
     J_segment       383..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           96 a          117 c          107 g          101 t
ORIGIN      
        1 acatgggggg agacacagtc aggacacagc atggacatga gggcccccgc tcatctccta
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac tcagtctcca
      121 tcttccctgt ctgcatctgt aggagacact gtcaccatct cttgccgggc aagtcagggt
      181 attagcagtt ctttaagttg gtttcagcag aaaccaggga aagcccctca gctcctcatc
      241 tatgctgcat ccagtttggc cggtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattct ctctcaccat caccagcctg cagcctgaag attttgcaac ttatttctgt
      361 ctgcagttta aaacttaccc gaacagtttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01005906             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20251:14963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005906
VERSION     KCVT01005906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20251:14963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83431.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggcttc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaccctcttg gatggtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005907             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8550:7681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005907
VERSION     KCVT01005907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8550:7681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83432.1"
                     /translation="CQQYNTLPLTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          108 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccttcaag gttcagtggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatacttta ccgttgacgt tcggccaagg aaccaaggtg gaaatcaaag
      421 gag
//
LOCUS       KCVT01005908             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11075:13285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005908
VERSION     KCVT01005908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11075:13285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83433.1"
                     /translation="CQEYINSPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          109 g           93 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtgccaccgg acaagttata ttgactcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtggat
      301 ctgggacaga gttcactctc agtatccgca gcctggaacc tgaagatttt gcagtgtatt
      361 actgtcagga gtatattaac tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01005909             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:15807:8651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005909
VERSION     KCVT01005909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:15807:8651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..371
                     /note="immunoglobulin light chain variable region"
     V_region        50..371
     V_segment       50..324
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83434.1"
                     /translation="CQQYNGYPPTF"
     J_segment       337..371
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>374
                     /gene="IGKC"
BASE COUNT           99 a          102 c           92 g           81 t
ORIGIN      
        1 acatggggga gtcagaacca ctcagctctg gctcccaggt gccagatgtg acatccagat
       61 gacccagtct ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg
      121 ggcaagtcag ggcattacca atgatttagc ctggtatcag cagaaaccag ggaaagcccc
      181 gaagcccctg atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg
      241 cagtggatct gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc
      301 aacttattat tgtcaacagt ataatggata ccctccgacg ttcggccaag ggaccagggt
      361 ggaaatcaaa cgag
//
LOCUS       KCVT01005910             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20748:19041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005910
VERSION     KCVT01005910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20748:19041"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83435.1"
                     /translation="CQQYNSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          107 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtagttat ttaaattggt atcaacagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcaacctgca acctgaggat tttgcaagtt attactgtca
      361 acagtataat agtttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005911             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:26038:9497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005911
VERSION     KCVT01005911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26038:9497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83436.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaata gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005912             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24714:7543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005912
VERSION     KCVT01005912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24714:7543"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83437.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005913             509 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22844:10007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005913
VERSION     KCVT01005913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 509)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22844:10007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..506
                     /note="immunoglobulin light chain variable region"
     V_region        185..506
     V_segment       185..468
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <446..>478
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83438.1"
                     /translation="CQQDYSWPLTF"
     J_segment       470..506
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        507..>509
                     /gene="IGKC"
BASE COUNT          129 a          136 c          136 g          108 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag gtgaggggaa catgaggtgg ttttgcacat
      121 cagtgaaaac tcctgccacc tctgctcagc aagaaatata attaaaattc aatataccac
      181 cggagaaata gtgatgacgc agtctccagc caccctgtct ttgtctccag gggaaagagc
      241 caccctctcc tgcagggcca gtcagagtgt tggcagcatc ttagcctggt accaccagaa
      301 acctgggcag gctcccaagt ccctcatcta tggtgcaacc agtagggcca ccggcatccc
      361 agacaggttc agtggcagtg ggtctggaac agagtttact ctcaccatca gcagcctgga
      421 gcctgaagat gttggcgttt attactgtca gcaggattat agctggccac tcactttcgg
      481 cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005914             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:29195:16550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005914
VERSION     KCVT01005914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:29195:16550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83439.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgtgc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005915             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24012:7945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005915
VERSION     KCVT01005915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24012:7945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83440.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          117 g          110 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgatgagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01005916             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23368:10671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005916
VERSION     KCVT01005916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23368:10671"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83441.1"
                     /translation="CQQYDSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          114 c          112 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggttc
      301 tgggacagaa ttcactctca ccatcaacag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005917             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:8807:7975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005917
VERSION     KCVT01005917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:8807:7975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83442.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          105 t
ORIGIN      
        1 actgggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01005918             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11467:15090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005918
VERSION     KCVT01005918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11467:15090"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83443.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01005919             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13513:8056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005919
VERSION     KCVT01005919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13513:8056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83444.1"
                     /translation="CQQVYSNPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          104 g          103 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccagatg acccagtctc
      121 catctgcctt gtctgcatct gtgggagaca gagtcaccgt ctcttgccgg gcaagtcaga
      181 acatttatag ttatttagcg tggtatcagc agaaaccagg gaaagcccct aagctcctca
      241 tctatgctac atccagattg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattctgca gcttattact
      361 gtcaacaggt ttatagtaac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01005920             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21321:6916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005920
VERSION     KCVT01005920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21321:6916"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..429
                     /note="immunoglobulin light chain variable region"
     V_region        108..429
     V_segment       108..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83445.1"
                     /translation="CQNYVRFSYSF"
     J_segment       392..429
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           97 a          123 c          117 g           95 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag tctcaggtac caccggacaa cttatattga
      121 ctcagtctcc agccaccctg tctttgtctc caggggagag agccaccctc tcctgcaggg
      181 ccagtcagag tgttggcagc agcttagcct ggtaccagca gagacctggg caggccccca
      241 ggctcctcat ctatggtgcg tccagcaggg ccactggcat cccagacagg ttcagtggca
      301 gtgggtctgg gacagaattc actctcacca tcagcagcct ggagcctgaa gattttgcag
      361 tgtattactg tcagaactat gttaggttct cgtacagttt tggccagggg accaaagtgg
      421 agatcaaacg ag
//
LOCUS       KCVT01005921             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21639:9912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005921
VERSION     KCVT01005921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21639:9912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83446.1"
                     /translation="CQQYDSLPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          113 c          107 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 tagtagttat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatggaaat cgtttggaag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgacgat tttgcaactt attactgtca
      361 acagtatgat agtttaccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01005922             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20170:8435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005922
VERSION     KCVT01005922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20170:8435"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83447.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          121 g          108 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005923             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:8977:2625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005923
VERSION     KCVT01005923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8977:2625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83448.1"
                     /translation="CQQYNNLPLTF"
     J_segment       386..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          108 a          112 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccagatg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcaa ttatttaaat tggtatcaac agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattcct
      361 gtcaacagta taataattta ccgttgacgt tcggccaagg gaccatggtg gatttcaaac
      421 gag
//
LOCUS       KCVT01005924             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11578:14145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005924
VERSION     KCVT01005924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11578:14145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..382
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83449.1"
                     /translation="CQQHNSYPRTF"
     J_segment       384..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           92 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtac cagatgtgac atccagatga cccagtctcc
      121 atcttccttg tctgcatctg taggagacag agtcaccatc acttgccaag ccagtcaggg
      181 tattggcaac tggttagcct ggtatcggca gaaaccaggg aaagccccta agctcctgat
      241 ctatgctgca tccagtttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcagcagcat aatagttatc ctcggacgtt cggccaaggg accaaggtgg aaatcaagcg
      421 ag
//
LOCUS       KCVT01005925             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:23564:19608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005925
VERSION     KCVT01005925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23564:19608"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83450.1"
                     /translation="CMQYRHIPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          118 c          114 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacatct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttattctgca tgcaatatag acacattcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01005926             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:7141:20272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005926
VERSION     KCVT01005926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:7141:20272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83451.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          120 c          108 g           89 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattaccaat gatttagcct ggtatcagca gagaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01005927             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15303:20347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005927
VERSION     KCVT01005927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15303:20347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83452.1"
                     /translation="CQQGYTYLYSF"
     J_segment       382..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          115 c          105 g          101 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gttggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctga
      241 tttatagggc atccagtttg caaagtgggt ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ctgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005928             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:23287:13775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005928
VERSION     KCVT01005928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23287:13775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83453.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          113 a          118 c          104 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcacg
      181 atattaacaa ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaggtcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggttctg
      301 ggacagattt cactctcacc atcaacaacc tgcagcctga agatatcgca acatattact
      361 gtcaacaaca tgatgattcc cctcggacct tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01005929             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:3954:13342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005929
VERSION     KCVT01005929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3954:13342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83454.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc aacacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005930             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:25439:12386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005930
VERSION     KCVT01005930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25439:12386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..362
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83455.1"
                     /translation="CQQYDSDLFTF"
     J_segment       366..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           93 a          112 c          108 g           91 t
ORIGIN      
        1 acatgggcac agcatggaca tgagggtccc cgctcagctc ctaggactcc tgctgctctg
       61 tctcccaggt gccaaatgtg acatccagat gacccagtct ccatcctccc tgtctgcatt
      121 tgtcggagac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca gttacttagc
      181 gtggtatcag cagagaccag ggaaagcccc gaagcccttg atctactacg cgtccacttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc gacttattac tgtcagcagt atgacagtga
      361 cctgttcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01005931             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:4298:10081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005931
VERSION     KCVT01005931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4298:10081"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83456.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005932             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16780:14214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005932
VERSION     KCVT01005932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16780:14214"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..327
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83457.1"
                     /translation="CQQHDNSPWTF"
     J_segment       328..365
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           96 a           98 c           95 g           79 t
ORIGIN      
        1 acatgggggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      121 tcagagtatt aacgactggt tggcctggta tcaacagaga ccagggaagg cccctaagct
      181 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      241 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      301 ttactgtcaa cagcatgata attccccgtg gacgttcggc caagggacca aggtggaaat
      361 caaacgag
//
LOCUS       KCVT01005933             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12882:20726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005933
VERSION     KCVT01005933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12882:20726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83458.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          111 c          112 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tactgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcatta tcacttgtcg ggcgagtcag
      181 gacattagaa gttatttagc gtggtatcgg cagaagccag ggaaagcccc ggagcccttg
      241 atctattacg catccgtttt ggaaaatggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgg aacttattac
      361 tgtcaacagt atgacagtga ctcactcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005934             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18493:15799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005934
VERSION     KCVT01005934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18493:15799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83459.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          127 c          108 g           87 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtcat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccaa cacaaacctg ggcaggctcc caaactcctc
      241 ctctatggtg catccaccag ggccaccggc atcccagaca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005935             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:23479:14748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005935
VERSION     KCVT01005935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23479:14748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83460.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          119 c          125 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagcggg gacattgtga tgacccagac
      121 tccactctcc ctgtccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatggtgagg atggaaacac ctacttggaa tggtatttcc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaagcgg gcctctggag tcgcagacag
      301 gttcagtggc agtgggtcag gcactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttatcact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005936             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14645:15431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005936
VERSION     KCVT01005936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14645:15431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83461.1"
                     /translation="CMQSLEIPPTF"
     J_segment       350..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           86 a          100 c          109 g           92 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      121 gtcagagcct ctttgacagt gggcatggaa acagctattt ggattggtac ctgcagaagc
      181 caggccagtc tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tgggatttat tactgcatgc aatctctaga gattcctccc actttcggtg
      361 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005937             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14661:15773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005937
VERSION     KCVT01005937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14661:15773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83462.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          107 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005938             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6933:16644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005938
VERSION     KCVT01005938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6933:16644"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83463.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          124 c          112 g           85 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca acagcttagc ctggtaccaa caaaaacctg ggcagcctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagagg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005939             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25835:13338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005939
VERSION     KCVT01005939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25835:13338"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83464.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005940             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14936:16200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005940
VERSION     KCVT01005940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14936:16200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83465.1"
                     /translation="CQQYDSDLFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cctgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01005941             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5190:11926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005941
VERSION     KCVT01005941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5190:11926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..285
                     /note="immunoglobulin light chain variable region"
     V_region        5..285
     V_segment       5..233
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83466.1"
                     /translation="CLQGYNIPYNF"
     J_segment       248..285
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           81 a           64 c           76 g           67 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gccgggcaag tcaggacatt agcgattatt
       61 taagttggta tcagcagaaa ccaggaaaag ctcctaagcg cctgatctat gctgtgtcca
      121 gtttggaagg tggggtccca tcaagattca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcgactta ttactgtcta cagggttata
      241 atatcccgta caattttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01005942             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14989:13942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005942
VERSION     KCVT01005942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14989:13942"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83467.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005943             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21108:15707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005943
VERSION     KCVT01005943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21108:15707"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83468.1"
                     /translation="CQQYTSFPLTF"
     J_segment       384..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          121 c          105 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtgagga
      181 cgttagcagt catttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctaat
      241 ctattttgca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcaacctgag gactttgcaa cttatcactg
      361 tcaacagtac actagtttcc ccctcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01005944             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16499:12618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005944
VERSION     KCVT01005944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16499:12618"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83469.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca ttgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005945             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8313:15447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005945
VERSION     KCVT01005945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8313:15447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83470.1"
                     /translation="CQQNSNRPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaattgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagtagttta gcctggtacc agcagagacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcgtccagc agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc cgaagatgtt gcagtttatt
      361 tttgtcagca gaatagtaat cggccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01005946             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:27520:10921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005946
VERSION     KCVT01005946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:27520:10921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83471.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          119 c          114 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagacat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccaac agggccaccg gcatcccaga caggttcagt ggcagtggct
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggaatttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005947             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19258:15432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005947
VERSION     KCVT01005947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19258:15432"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83472.1"
                     /translation="CIQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          118 g          110 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcct tctcctgtag gtctagtcac
      181 agcctcttgg atagtgagga tggatatatc catttggatt ggtatctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 tttagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagggt ggaggctgag
      361 gatgttgggg tttactactg catacaatct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01005948             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10339:13121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005948
VERSION     KCVT01005948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10339:13121"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83473.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          120 c          109 g           89 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagc ctggtatcag cagagaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005949             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:25329:8334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005949
VERSION     KCVT01005949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25329:8334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83474.1"
                     /translation="CLQSKNSPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          104 a          115 c          113 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcgtc tgcagagcca gtgagagtga
      181 caatgtcttt ggaataaacc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 acccctgatt taccaagcat ccaataaaga aactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgacg atgctgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggacgttt ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01005950             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7485:17639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005950
VERSION     KCVT01005950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7485:17639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83475.1"
                     /translation="CQQHNNYSPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          104 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccacc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcaatgat ttagcctggt atcagctgaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaacataat aattactctc ccactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005951             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24948:22174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005951
VERSION     KCVT01005951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24948:22174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83476.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcact
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005952             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10924:7258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005952
VERSION     KCVT01005952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10924:7258"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83477.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          127 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcaactta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg ccatcccatc caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggaggtca
      421 aacgag
//
LOCUS       KCVT01005953             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24371:17316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005953
VERSION     KCVT01005953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24371:17316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83478.1"
                     /translation="CQKYSNSHAVTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           99 a          125 c          112 g           91 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 actgttggca gcagcttagc ctggtaccag cagaatcctg ggcaggcccc caggctcctc
      241 atctatggta catcccgcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagtctg aagattttgc aatgtattac
      361 tgtcagaaat atagtaactc ccacgcggtc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01005954             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20469:3907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005954
VERSION     KCVT01005954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20469:3907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83479.1"
                     /translation="CMQALEFPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           93 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta atcagagcct
      181 cttggatagt gaggatggaa acacctattt ggagtggcac ctgcagaagc caggccagtc
      241 tctacaactc ttgatttatg aggtttccta ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat ttctgcatgc aggctctaga gtttcctctc actttcggcg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01005955             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12830:3996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005955
VERSION     KCVT01005955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12830:3996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83480.1"
                     /translation="CQQYNSLPLSF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          109 c          106 g          100 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagtgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aactcctgat
      241 ctattatgca aaccgtttag aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacttgaa gattttgcaa cttattactg
      361 tcaacaatat aatagtttac cgctctcttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005956             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19554:19046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005956
VERSION     KCVT01005956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19554:19046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..406
                     /note="immunoglobulin light chain variable region"
     V_region        85..406
     V_segment       85..363
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <346..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83481.1"
                     /translation="CQQGYSYPYSF"
     J_segment       369..406
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>409
                     /gene="IGKC"
BASE COUNT           97 a          115 c          105 g           92 t
ORIGIN      
        1 acatggggag gacacagcat ggacatgagg gtccccgctc agctccttgg gctcctgctg
       61 ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc ctccctgtcc
      121 gcatctgcag gagacacagt caccatcact tgccaggcga gtcaaggcat tggcaatact
      181 ttaaattggt atcaacagaa accggggaaa gcccctacac tcctgatcta tagggcatcc
      241 ggtttgcaaa gtgggactcc ctctcggttc agcggcagtg gatctgggac ggatttcact
      301 ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca acagggttat
      361 agttatccgt acagttttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01005957             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5281:21298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005957
VERSION     KCVT01005957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5281:21298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83482.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          125 c          113 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcagcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005958             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18051:14712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005958
VERSION     KCVT01005958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18051:14712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83483.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          116 c          103 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagtagtct gcagcctgag gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg ataccaaacg
      421 ag
//
LOCUS       KCVT01005959             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17731:8925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005959
VERSION     KCVT01005959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17731:8925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83484.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          116 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggatcacga ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagtcaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01005960             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17957:12108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005960
VERSION     KCVT01005960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17957:12108"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..433
                     /note="immunoglobulin light chain variable region"
     V_region        97..433
     V_segment       97..395
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83485.1"
                     /translation="CLQDIQLPLTF"
     J_segment       396..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT           87 a          122 c          121 g          106 t
ORIGIN      
        1 atgggggatc aggactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 gggctgctgg tgctctggct ccctgggacc agtggggata ttatgatgac tcagactcca
      121 ctctccctgt ccgtcacccc tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcctgcata ggaatgggta cacctatttg ttttggtacc tgcagaagcc aggccagtct
      241 ccacagctcc tgatctattt cggttccaac cgggcctctg gagtcccaga caggttcagt
      301 gccagtgggt caggcactga tttcacactg aaaatcagcc gggtggaggc tgaggatgtt
      361 ggggtttatt actgcttgca agatatacaa cttccgctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01005961             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14572:13190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005961
VERSION     KCVT01005961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14572:13190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83486.1"
                     /translation="CLQGYITPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          112 c          112 g           99 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatca gtaggagaca gagtcgccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcgcc atcagtagcc tgcagcctga agattttgcg gcttattact
      361 gtctacaggg ttatattacc ccgtacagtt ttggccaggg gaccaaagtg gagagcaaac
      421 gag
//
LOCUS       KCVT01005962             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:27746:8062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005962
VERSION     KCVT01005962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:27746:8062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83487.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          109 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcattgacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggttctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005963             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15950:19255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005963
VERSION     KCVT01005963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15950:19255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83488.1"
                     /translation="CQQNNKWPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          122 c          117 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tggacaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gctgtttatt
      361 attgtcagca gaataataag tggcctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005964             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19933:17310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005964
VERSION     KCVT01005964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19933:17310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83489.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          119 c          109 g           91 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc tcttgccggg cgagtcagga
      181 cattcgcagt tatttagcgt ggtatcagca gagaccaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01005965             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:5766:12116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005965
VERSION     KCVT01005965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5766:12116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83490.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtccccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcat tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005966             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25114:9996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005966
VERSION     KCVT01005966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25114:9996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83491.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          120 c          107 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacaac ataatggata ccctccgacg ttcggccaag ggaccaggtt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01005967             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4012:12241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005967
VERSION     KCVT01005967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4012:12241"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83492.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagcgtg gaggctgaag
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005968             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13378:19770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005968
VERSION     KCVT01005968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13378:19770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..401
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83493.1"
                     /translation="CMQDIQLPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           86 a          125 c          122 g          108 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctggggct gctgttgctc tggctccctg ggaccagtgg ggatattgtg ctgactcaga
      121 ctccactctc cctgcccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct gcatagtaat ggatacacct atttgttttg gtacctgcag aggccaggcc
      241 agtctccaca acttctggtc tatttgggtt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgcaaat cagccgggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagata tacagcttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005969             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15040:11159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005969
VERSION     KCVT01005969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15040:11159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..307
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83494.1"
                     /translation="CQQNSNWPLTF"
     J_segment       308..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           86 a           97 c           95 g           69 t
ORIGIN      
        1 acatgggcca gataccaccg gagaaatagt gatgacgcag tctccagcca ccctgtcttt
       61 gtctccagga gaaagagcca ccctctcctg cagggccagt cagagtgtca gcagcagcgt
      121 agcctggtac cagcagaaac ctgggcaggc tcccagactc ctcatctatg gtgcatccaa
      181 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcactct
      241 caccatcagc agcctggagc ctgaagatgt tgcactttat tattgtcagc agaatagtaa
      301 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01005970             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20263:9380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005970
VERSION     KCVT01005970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20263:9380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83495.1"
                     /translation="CQHSYGTLTWAF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggggac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaagg actatttaca ttggtatcag cagaaaccag gaaaagcccc taggctcctg
      241 atctatgctg catctacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggggcagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcata gttatggtac cctcacgtgg gcgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01005971             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20934:18705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005971
VERSION     KCVT01005971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20934:18705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83496.1"
                     /translation="CQQYNSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          114 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagca gttatttagc gtggtatcgg cagaagccag ggaaagcccc ggagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgg aacttattac
      361 tgtcaacagt ataacagtga ctcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005972             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10692:17065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005972
VERSION     KCVT01005972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10692:17065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83497.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggcacc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01005973             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15660:9870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005973
VERSION     KCVT01005973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15660:9870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..276
                     /note="immunoglobulin light chain variable region"
     V_region        7..276
     V_segment       7..239
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83498.1"
                     /translation="CQQNSNWPLTF"
     J_segment       240..276
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           67 a           78 c           77 g           57 t
ORIGIN      
        1 acatgggagc caccctctcc tgcagggcca gtcagagtgt cagcagcagc ttagcctggt
       61 accaacaaaa acctgggcag gctcccaggc tcctcatcta tggtgcatcc agcagggcca
      121 ctggcatccc agacaggttc agtggcagtg ggtctgggac agacttcact ctcaccatca
      181 ccagcctgga gcctgaagat gttgcagttt attattgtca gcagaatagt aactggcctc
      241 tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005974             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20774:17269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005974
VERSION     KCVT01005974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20774:17269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83499.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          109 c          110 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtcg gagacagagt cagcatcact tgccgggcaa gtcagggcat
      181 tagtagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctcatcta
      241 ttatgcaaac cgtttggaga gtggggtccc atcaaggttc agcggcagtg ggtctgggac
      301 agaattcact ctcatcatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005975             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5050:4754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005975
VERSION     KCVT01005975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5050:4754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..365
                     /note="immunoglobulin light chain variable region"
     V_region        42..365
     V_segment       42..327
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83500.1"
                     /translation="CVQALEFPWTF"
     J_segment       328..365
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           83 a           96 c          101 g           88 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccac tctccctgcc
       61 cgtcaccctt ggagagccgg cctccatctc ctgcaggtct agtcagagcc tcttggatag
      121 tgaggatgga aacacctatt tggattggta cctgcagaag ccaggccagt ctccacaact
      181 cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg
      241 gtctgacact gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta
      301 ttactgcgtt caagctctag agtttccgtg gactttcggc caagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01005976             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20697:14959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005976
VERSION     KCVT01005976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20697:14959"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83501.1"
                     /translation="CQQYDSDPFTF"
     J_segment       271..306
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           79 a           76 c           83 g           71 t
ORIGIN      
        1 acatgggatc ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga
       61 gtcagggcat tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg
      121 ccttgatcta ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg
      181 gatctgggac agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      241 attactgtca acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga
      301 tcaaacgag
//
LOCUS       KCVT01005977             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:25737:9877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005977
VERSION     KCVT01005977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25737:9877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83502.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtgcg gacattgtga tgacccagac
      121 tccactctcc ctggccgtca ctcttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gatcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01005978             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15760:7099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005978
VERSION     KCVT01005978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15760:7099"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83503.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005979             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6961:10222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005979
VERSION     KCVT01005979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6961:10222"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..436
                     /note="immunoglobulin light chain variable region"
     V_region        102..436
     V_segment       102..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83504.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          117 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtt atgacccaga
      121 ctccactctc cctgcccgtc acccttgagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat caccagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01005980             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23733:4560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005980
VERSION     KCVT01005980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23733:4560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83505.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg acatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01005981             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11519:21367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005981
VERSION     KCVT01005981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11519:21367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..358
                     /note="immunoglobulin light chain variable region"
     V_region        45..358
     V_segment       45..320
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <298..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83506.1"
                     /translation="CMQPLEFPWTF"
     J_segment       321..358
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>361
                     /gene="IGKC"
BASE COUNT           84 a           92 c          102 g           83 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcccgtcacc
       61 cttggagagc cggcctccat ctcctgtggg tctagtcaga gcctcttgga tagtgaggat
      121 ggaaacacct atttggaatg gtacctgcag aagccaggcc agtctccaca gctcttgatt
      181 tatgaggttt ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac
      241 actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc
      301 atgcaacctc tagagtttcc gtggacgttc ggccaaggga ccaaggtgga aatcaaacga
      361 g
//
LOCUS       KCVT01005982             553 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:13088:4870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005982
VERSION     KCVT01005982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 553)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13088:4870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    226..550
                     /note="immunoglobulin light chain variable region"
     V_region        226..550
     V_segment       226..510
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <487..>522
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83507.1"
                     /translation="CQQYNSYPPWTF"
     J_segment       513..550
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        551..>553
                     /gene="IGKC"
BASE COUNT          136 a          141 c          139 g          137 t
ORIGIN      
        1 acatgggggg aatcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg taaggaagga gaacactagc agtttacaca
      121 gcccagggtt ctgagtactg cttcactatt cagggaaact ctcttacaac atgattaatt
      181 atgaggacat ttgtttttat gtttccaatc tcacgtgcca gatgtgacat tcagatgacc
      241 cagtctccat cctccctgtc tgcatctctg ggagacacag tcaccatcac ttgtcgggca
      301 agtcagggca ttatcagtta tttagcctgg tatcagcaga aaccagggaa agcccctaag
      361 cgcctgatgt atggtacgtc gactttgcaa agtggggtcc catcagggtt cagtggcagt
      421 gggtctggga cagatttcac tctcaccgtc agcagcctgc agcctgaaga ttttgcaact
      481 tatttctgtc aacagtataa tagttaccct ccgtggacgt tcggccaggg gaccaaggtg
      541 gaaatcaaac gag
//
LOCUS       KCVT01005983             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22908:9550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005983
VERSION     KCVT01005983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22908:9550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83508.1"
                     /translation="CQQYNSLPFTF"
     J_segment       384..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          106 a          114 c          102 g          102 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcgcttgccg ggcaagtcag
      181 gacattggct attttttaaa ttggtatcaa cagaaaccgg gaaaagcccc taagctccta
      241 ctctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accattcact tttggccccg ggaccaaact ggatatcaga
      421 cgag
//
LOCUS       KCVT01005984             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20906:9195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005984
VERSION     KCVT01005984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20906:9195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83509.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtttttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaggtca
      421 aacgag
//
LOCUS       KCVT01005985             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18069:6150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005985
VERSION     KCVT01005985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18069:6150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83510.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005986             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:10341:6034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005986
VERSION     KCVT01005986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10341:6034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83511.1"
                     /translation="CQQYNSFPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          113 c          104 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct ataggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattatcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt caccctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagtttt cctcccactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01005987             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:6895:18948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005987
VERSION     KCVT01005987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6895:18948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83512.1"
                     /translation="CVQALEFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          118 c          119 g          105 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccaa tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggattggtac ctgcagaagc caggccagtc
      241 tccacaactc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tctgacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcgttc aagctctaga gtttccgtgg actttcggcc aagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01005988             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6582:7269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005988
VERSION     KCVT01005988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6582:7269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..411
                     /note="immunoglobulin light chain variable region"
     V_region        98..411
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83513.1"
                     /translation="CQQYNNLPLTF"
     J_segment       385..411
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>422
                     /gene="IGKC"
BASE COUNT          106 a          112 c          106 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcgtctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagcaat tatttaaatt ggtatcaaca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattcctg
      361 tcaacagtat aataatttac cgttgacgtt cggccaaggg accatggtgg atttcaaacg
      421 ag
//
LOCUS       KCVT01005989             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25342:20155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005989
VERSION     KCVT01005989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25342:20155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83514.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           90 a          119 c          124 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaatcacct acttggaatg gtttttccag aagccaggac
      241 agtctccgca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttttcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01005990             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:23440:12467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005990
VERSION     KCVT01005990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23440:12467"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83515.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc ggcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01005991             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:21890:11711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005991
VERSION     KCVT01005991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21890:11711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    25..328
                     /note="immunoglobulin light chain variable region"
     V_region        25..328
     V_segment       25..290
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <268..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83516.1"
                     /translation="CMQPLEFPWTF"
     J_segment       291..328
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>331
                     /gene="IGKC"
BASE COUNT           79 a           79 c           97 g           76 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc cttggagagc cggcctccat ctcctgtggg
       61 tctagtcaga gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag
      121 aagccaggcc agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc
      181 ccagacaggt tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg
      241 gaggctgagg atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc
      301 ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01005992             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25496:11214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005992
VERSION     KCVT01005992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25496:11214"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..405
                     /note="immunoglobulin light chain variable region"
     V_region        103..405
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83517.1"
                     /translation="CQKYSSSPFTF"
     J_segment       387..405
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           88 a          119 c          107 g           91 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat tttgactcag
      121 tctccagcca ccctgtcttt gtctctaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc ccccagactc
      241 ctcgtctatg gtgcatccag gagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt tgcagtgtat
      361 tactgtcaga agtatagtag ttccccattc actttcggcc ccggg
//
LOCUS       KCVT01005993             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20465:9102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005993
VERSION     KCVT01005993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20465:9102"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83518.1"
                     /translation="CQQGYNTPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          113 c          115 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcaggatat
      181 tagcagctgg ttagcctggt atcagctgaa gccggggaaa gcccctaaac tcttgatcta
      241 taaggcgtcc agtttggcaa gaggggtccc atcgaggttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagtctgca gcctgaagat tttgcatctt attattgtca
      361 acagggttac aataccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01005994             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7652:10876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005994
VERSION     KCVT01005994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7652:10876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83519.1"
                     /translation="CQQYNSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          112 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtcaattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caactactta
      361 ctgtcaacag tataacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01005995             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5614:10988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005995
VERSION     KCVT01005995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5614:10988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83520.1"
                     /translation="CQQYNSDPYSF"
     J_segment       348..385
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           97 a           99 c          100 g           92 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaat
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagtc
      121 accatcactt gtcgggcgag tcaggacatt aggaattatt tagcgtggta tcagcagaaa
      181 ccagggaaag ccccgaaggc cttgatctat tacacatcca ttttggaaaa tggggtccca
      241 tcaaggttca gcggtggtgg atctgggaca gaattcagtc tcaccatcag cagcctgcag
      301 gctgaggatt ttgcaactta ttactgtcaa cagtataata gtgacccgta cagttttggc
      361 caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01005996             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:8574:15298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005996
VERSION     KCVT01005996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8574:15298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83521.1"
                     /translation="CQQGNSIPLTF"
     J_segment       389..426
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          108 a          115 c          107 g           99 t
ORIGIN      
        1 acatggggac gtttagcctg tgacagggct cagctaacat aatggatttt caggctcaaa
       61 ttttcatctt ccttctgctc agtgtcacag tgtccaatgg agaaattgtg ctgacccagt
      121 ctccaacatc catggctgtc tcccaaggag aaagagtcac catctcctgc acggccagtt
      181 caagtgtaag caccagctac ctgcactggt accaacagaa gccaggattc cctccaaggc
      241 ttcttgtcca tagaacatca agtctggctt ctggggtccc agccaggttc agtggcagcg
      301 gttctgggac ctcttacacg ctcacaatca gcagcatgga ggctgaagat gctgcaaact
      361 attactgtca gcaggggaat agcattccgc tcactttcgg cggagggacc aaggtggaga
      421 tcaaacgag
//
LOCUS       KCVT01005997             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:4463:6550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005997
VERSION     KCVT01005997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4463:6550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83522.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          113 g           91 t
ORIGIN      
        1 acagggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtccgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagagaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacctattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01005998             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:12136:6177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005998
VERSION     KCVT01005998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12136:6177"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83523.1"
                     /translation="CLQYKIYPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          114 c          100 g          103 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgca ggagacactg tcaccatcac ttgccgggca agtcagggtg
      181 ttggtaccta tttaaattgg tttcagcaga aaccagggaa agcccctaac ctcctgatct
      241 atgctgcatc tagtctggaa agtggggtcc catcaaggtt cagcggcagt ggatttggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 tacagtataa aatttatcca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01005999             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20810:11529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01005999
VERSION     KCVT01005999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20810:11529"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83524.1"
                     /translation="CQQYDSDPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          102 a          115 c          108 g           93 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcttg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 agcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 ttcgcatcca ctttggaaag tggcgtccca tcaaggttca gcggcagtgg atctgggaca
      301 gagttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtatgaca gtgacccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01006000             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:25215:9273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006000
VERSION     KCVT01006000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25215:9273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83525.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          101 a          119 c          118 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccaaag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtgacagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006001             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14946:9355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006001
VERSION     KCVT01006001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14946:9355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83526.1"
                     /translation="CQQYNTLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          108 c          106 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat actttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006002             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20040:16195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006002
VERSION     KCVT01006002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20040:16195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83527.1"
                     /translation="CQQGYRYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          106 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tgacattaat ttaaattact atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc cgtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agatacccgt acagttttgg ccaggggacc aaagtggaga tgaaacgag
//
LOCUS       KCVT01006003             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20852:12126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006003
VERSION     KCVT01006003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20852:12126"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83528.1"
                     /translation="CQQYNSLPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          106 a          115 c          102 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct actctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttaccagtta tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 attatgcaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcggcctgc aacctgaaga ttttgcaact tattactgtc
      361 aacagtataa tagtttacca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01006004             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18988:6480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006004
VERSION     KCVT01006004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18988:6480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83529.1"
                     /translation="CLQYKSFPYIF"
     J_segment       385..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          115 c           98 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat ttcgctactt attactgtct
      361 acagtataaa agtttcccgt atatttttgg ccaggggacc aaactggaga ccaaacgag
//
LOCUS       KCVT01006005             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:25850:18407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006005
VERSION     KCVT01006005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25850:18407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83530.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          118 c          127 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tggggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acgtagtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag tcggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctggg
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006006             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14731:19393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006006
VERSION     KCVT01006006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14731:19393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83531.1"
                     /translation="CLQGYNTPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          115 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg actatttaag ttggtatcag cagaaaccag gaaaagctcc taagcgcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggctct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gttataatac cccgtacaat tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006007             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19308:14022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006007
VERSION     KCVT01006007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19308:14022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83532.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006008             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7126:8257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006008
VERSION     KCVT01006008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7126:8257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..403
                     /note="immunoglobulin light chain variable region"
     V_region        101..403
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83533.1"
                     /translation="CQKYSSSPFTF"
     J_segment       385..403
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           87 a          120 c          106 g           90 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttattt tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccagactcct
      241 cgtctatggt gcatccagga gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagaag tatagtagtt ccccattcac tttcggcccc ggg
//
LOCUS       KCVT01006009             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16245:21514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006009
VERSION     KCVT01006009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16245:21514"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83534.1"
                     /translation="CQQGHSYPWTF"
     J_segment       383..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT           99 a          118 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag tcgagtctag
      181 gcattggcaa atttttaaat tggtatcagc agaaaccagg gaaagccccc aaactcctga
      241 tctatagggc atccagtttg caaactggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattc cactctcacc atcagcagcc tgcagcctga agattttgcc gcttattact
      361 gtcaacaggg tcatagttac ccgtggacgt tcggccaagg gaccaaggtg gagatgaaac
      421 gag
//
LOCUS       KCVT01006010             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20060:8567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006010
VERSION     KCVT01006010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20060:8567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..473
                     /note="immunoglobulin light chain variable region"
     V_region        137..473
     V_segment       137..435
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <413..>445
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83535.1"
                     /translation="CGQGTHLPLTF"
     J_segment       436..473
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        474..>476
                     /gene="IGKC"
BASE COUNT          110 a          122 c          142 g          102 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggtaagcgc agaagggaga tgagggagga gaatggggtg
      121 taaaggatcc agtggggatg ttgtgctgac tcagtctcca ctctccctgc ccatcacccc
      181 tggacagccg gcctccatct cctgcaggtc tagtcaaagc cttgtatata gcactggaaa
      241 cacatacttg agttggtatc aacagaagcc aggccaacct ccgaggcgcc taatttatga
      301 ggtttcttac cgggactctg gggtcccaga cagattcagc ggcagtgggg cagggacaga
      361 tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggggtttatt actgcgggca
      421 aggtacacac cttccgctca ctttcggcgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01006011             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23004:8357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006011
VERSION     KCVT01006011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23004:8357"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83536.1"
                     /translation="CMQALDFPLTF"
     J_segment       282..319
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           72 a           84 c           88 g           78 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtaatg acccagactc
      121 cactctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      181 ttcggtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      241 gatgttggga tttattactg catgcaagct ctagactttc cgctcacttt cggcggaggg
      301 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006012             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19915:11225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006012
VERSION     KCVT01006012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19915:11225"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83537.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaacct attactgtca
      361 acagtatgac agtgatccgt tcactttcgg tggggggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01006013             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14866:20453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006013
VERSION     KCVT01006013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14866:20453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83538.1"
                     /translation="CMQGKDFPYSF"
     J_segment       240..277
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           71 a           59 c           86 g           64 t
ORIGIN      
        1 acatgggggt ctagtcagag cctcttggat agtgaggatg gaaacaccta tttggaatgg
       61 tacctgcaga ggccaggcca gtctccacag cccttgattt atggggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      181 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaaggcaa agactttccg
      241 tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01006014             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22992:9929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006014
VERSION     KCVT01006014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22992:9929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83539.1"
                     /translation="CQQYNRFPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          110 c          107 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gccattagta attacttaaa ttggtatcag caaaagccgg ggaaagcccc aaagcccctg
      241 atttattatg taaaccgttt ggaaaatgga gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc aatttattac
      361 tgtcaacaat ataataggtt tcctctcact ttcggtgggg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006015             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18399:8714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006015
VERSION     KCVT01006015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18399:8714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83540.1"
                     /translation="CQQYNNLPYTF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          104 a          112 c          102 g          100 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg cttctttagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 agcagttttt tgaattggta tcagcagaaa ccggggaaag cccctaacct cctgatctat
      241 tttgcaaacc gtttggagag tggggtccca tcaaggttca gcggcagtgg gtctgggaca
      301 agattcactc tcaccatcag cagcctccaa cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataata atttaccgta cacttttggc caggggacca aagttgagat caaacgag
//
LOCUS       KCVT01006016             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:23308:3303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006016
VERSION     KCVT01006016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23308:3303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..415
                     /note="immunoglobulin light chain variable region"
     V_region        102..415
     V_segment       102..380
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83541.1"
                     /translation="CQQGHSYPWTF"
     J_segment       386..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>426
                     /gene="IGKC"
BASE COUNT          100 a          117 c          113 g           96 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tccttgggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacgcagt
      121 ctccatcctc cctgtccgca tctgtaggag acacagtcac gatcacttgc cagtcgagtc
      181 taggcattgg caaattttta aattggtatc agcagaaacc agggaaagcc cccaaactcc
      241 tgatctatag ggcatccagt ttgcaaactg ggattccctc tcggttcagc ggcagtggat
      301 ctgggacgga tttcactctc accatcagca gcctgcagcc tgaagatttt gccgcttatt
      361 actgtcaaca gggtcatagt tacccgtgga cgttcggcca agggaccaag gtggagatga
      421 aacgag
//
LOCUS       KCVT01006017             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13001:12497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006017
VERSION     KCVT01006017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13001:12497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..269
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83542.1"
                     /translation="CQQYNSDPRTF"
     J_segment       273..307
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>310
                     /gene="IGKC"
BASE COUNT           79 a           79 c           83 g           69 t
ORIGIN      
        1 acatgggcat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg
       61 agtcagggca ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag
      121 cccttgatct attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt
      181 ggatctggga cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact
      241 tattactgtc aacagtataa cagtgacccg cgcactttcg gtggagggac caaggtggag
      301 atcaaacgag
//
LOCUS       KCVT01006018             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18875:12286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006018
VERSION     KCVT01006018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18875:12286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..394
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83543.1"
                     /translation="CGQGTHLPLTF"
     J_segment       395..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          100 a          123 c          115 g           96 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccgaatccaa tggggatgtt gtgatgactc agtctccact
      121 ctccctgccc atcacccctg gacagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tctacacatc aatggagaca catacttgag ttggtatcaa cagaagccag gccaacctcc
      241 aaggcgccta atttatgagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggagcctg aggatgttgg
      361 ggtttattac tgcgggcaag gtacacacct tcctctcact ttcggcggag gcaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01006019             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10414:5496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006019
VERSION     KCVT01006019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10414:5496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83544.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          119 c          116 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggaatttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006020             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18901:9968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006020
VERSION     KCVT01006020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18901:9968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83545.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          112 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atccttcctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcga cttattactg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006021             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:16645:13229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006021
VERSION     KCVT01006021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16645:13229"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83546.1"
                     /translation="CQQHNNYSPTF"
     J_segment       367..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          107 a          112 c          100 g           85 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccaccctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattagca atgatttagc
      181 ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg atctattacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacaac ataataatta
      361 ctctcccact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006022             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17175:9403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006022
VERSION     KCVT01006022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17175:9403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83547.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          110 a          118 c          106 g           86 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcacagcc agtcacgata
      181 taaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaag ctcctgatct
      241 acagggcatc caatttggaa acaggggtcc catcgaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcagcatc agcagcctgc agcctgaaga tttcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006023             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:26203:13036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006023
VERSION     KCVT01006023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:26203:13036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83548.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          117 c          101 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa gccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagtctgca gcctgaggat tttgcaactt attactgtca
      361 acagtataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01006024             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19342:19313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006024
VERSION     KCVT01006024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19342:19313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83549.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006025             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4780:18921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006025
VERSION     KCVT01006025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4780:18921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..425
                     /note="immunoglobulin light chain variable region"
     V_region        96..425
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83550.1"
                     /translation="CLQSKNSPWTF"
     J_segment       392..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>432
                     /gene="IGKC"
BASE COUNT           98 a          113 c          117 g          104 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggatgca atggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc actgagagtg
      181 tcagtttgtt tggaataagc ctcattcact ggtatcagca gaaaccggga caacctccta
      241 aactcctgat ttaccaagca ttcaatagag agactggggt cccagtcagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaagctgac gatgctgcag
      361 attatttctg tctgcagagt aagaattctc cgtggacttt cggccaaggg accaaggtgg
      421 aaatcgaacg ag
//
LOCUS       KCVT01006026             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22297:13882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006026
VERSION     KCVT01006026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22297:13882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83551.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006027             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9094:6777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006027
VERSION     KCVT01006027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9094:6777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83552.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaatctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01006028             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18045:6926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006028
VERSION     KCVT01006028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18045:6926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83553.1"
                     /translation="CQQYDSFPLTF"
     J_segment       386..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          117 c          109 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtgggagac agagtcacca tcacttgccg ggctagtcag
      181 gacattagta attttttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattatg gaaaccgttt gggaagcggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc gacttatcat
      361 tgtcagcagt atgatagttt ccccctcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006029             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:2688:13317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006029
VERSION     KCVT01006029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2688:13317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83554.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          117 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgagaatc agcagagtag aggctgagga
      361 tgttggagtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006030             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19453:10557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006030
VERSION     KCVT01006030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19453:10557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83555.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          109 c          109 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcacc tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006031             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7496:12198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006031
VERSION     KCVT01006031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7496:12198"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83556.1"
                     /translation="CQQDFGWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          121 c          121 g           92 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagactgttg gcagcgcctt agcctggtac cagcagaaac ctgggcagac
      241 tcacaaactc ctcatttatg gtgcatccat cagggccacc ggcatcccag acaggttcag
      301 tggcagtggg tctggaacag agttcactct caccatcagt agtccggagc ctgaggatgt
      361 tggagtttat tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006032             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21730:17993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006032
VERSION     KCVT01006032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21730:17993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..318
                     /note="immunoglobulin light chain variable region"
     V_region        8..318
     V_segment       8..280
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83557.1"
                     /translation="CQQYDSDPYSF"
     J_segment       281..318
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           83 a           84 c           81 g           73 t
ORIGIN      
        1 acatggggac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
       61 cttgtcgggc gagtcaggac attagcagtt atttagcgtg gtatcagcag aaaccaggga
      121 aagccccgaa gcccttgatc tatttcgcat ccactttgga aagtggcgtc ccatcaaggt
      181 tcagcggcag tggatctggg acagagttca ctctcaccat cagcagcctg cagcctgaag
      241 attttgcaac ttattactgt caacagtatg acagtgaccc gtacagtttt ggccagggga
      301 ccaaagtgga catcaaacga g
//
LOCUS       KCVT01006033             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21022:13683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006033
VERSION     KCVT01006033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21022:13683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83558.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           85 a          124 c          123 g          105 t
ORIGIN      
        1 catgggggat caggactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 ggggctgctg gtgctctggc tccctgggac cagtggggat attgtgatga ctcagactcc
      121 actctccctg tccgtcgccc ctggagagcc ggcctccatc tcctgcaggt ctagccagag
      181 cctcctgcat aggaatggat acacctattt gttttggtac ctgcagaagc caggccagtc
      241 tccacagctc ctgatctatt tgggttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcaggcactg atttcacact gcaaatcagc cgggtggagg ctgaggatgt
      361 tggggtttat tactgcttac aagatataca gcttcctctc actttcggcg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01006034             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8476:10555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006034
VERSION     KCVT01006034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8476:10555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83559.1"
                     /translation="CMQGTQLLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          117 c          113 g           97 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc cttctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca accggcctcc atctcctgca ggtctagtca aagccttcta
      181 cacactgatg ggaaaaccta cttgaattgg tatcagcaga agccaggcca acctccaagg
      241 cgcctaattt atcaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg agactgagga tgttggagtt
      361 tattactgca tgcaaggtac acagcttctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006035             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:17005:6453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006035
VERSION     KCVT01006035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17005:6453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83560.1"
                     /translation="CQQYNTLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          113 c          102 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacgtt cagatgaccc agtctccatc
      121 ctacctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacgtttat ttaaattggt atcaccaaaa accggggaaa gcccctaacc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc gtcaaggttc agcggcagtg tatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcgactt attactgtca
      361 acagtacaat actttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006036             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:15759:20083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006036
VERSION     KCVT01006036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15759:20083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83561.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          123 c          112 g           85 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag caaaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca gattcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006037             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23416:19079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006037
VERSION     KCVT01006037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23416:19079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83562.1"
                     /translation="CQQYNSLPWTF"
     J_segment       307..344
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           96 a           85 c           84 g           82 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatcct ccctgtctgc
       61 atctgtagga gacagagtca ccatcacttg ccgggcaagt cagggcatta gttattattt
      121 aaattggtat caacagaaac cggggaaagc ccctaaggtc ctgatctatt acacaaaccg
      181 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcagc agcctgcaac ctgaggattt tgcaagttat tactgtcaac aatataatag
      301 tttaccgtgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01006038             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24360:8929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006038
VERSION     KCVT01006038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24360:8929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..366
                     /note="immunoglobulin light chain variable region"
     V_region        87..366
     V_segment       87..329
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83563.1"
                     /translation="CQQDFDWPPTF"
     J_segment       332..366
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           87 a          108 c          100 g           74 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag gggaaagagc caccctctcc tgcagggcca
      121 gtcagagtgt tggcaacacc ttaacctggt accagcacaa acctgggcag gctcccaagc
      181 tcctcctcta tggtgcatcc accagggcct ccggcatccc aggcaggttc agtgccagtg
      241 ggtctggaac agagtttact ctcaccatca gcagcctgga gcctgaagat gttggaattt
      301 attactgtca gcaggatttt gactggcctc cgacgttcgg ccaagggacc aaggtggaaa
      361 tcaaacgag
//
LOCUS       KCVT01006039             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22137:8881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006039
VERSION     KCVT01006039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22137:8881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83564.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          119 c          106 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagtc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006040             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17179:5035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006040
VERSION     KCVT01006040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17179:5035"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83565.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gaaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acatacgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006041             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12522:3306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006041
VERSION     KCVT01006041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12522:3306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..307
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83566.1"
                     /translation="CQQGNSNPLTF"
     J_segment       308..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           93 a           87 c           85 g           82 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgtcccag tttccatcct ccctgtctgc
       61 atctgtagga gacagagtca ccatcacttg ccgggcaagt caggccatta gcagttattt
      121 aaattggtat cagcagaaac cggggaaagc ccctaaactc ctgatatact atggaaaaag
      181 tttggcaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcacc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agggtaatag
      301 taatcctctc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006042             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12279:16997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006042
VERSION     KCVT01006042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12279:16997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..428
                     /note="immunoglobulin light chain variable region"
     V_region        108..428
     V_segment       108..390
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83567.1"
                     /translation="CLQFKTFPYSF"
     J_segment       391..428
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          119 c          109 g          104 t
ORIGIN      
        1 acatgggggt ttgcaggagt cagacacagt caggacacag catggacatg agggcccccg
       61 ctcatctcct agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga
      121 ctcagtctcc atcttccctg tctgcatctg taggagacac tgtcaccatc tcttgccggg
      181 caagtcaggg tattagcagt tctttaagtt ggtttcagca gaaaccaggg aaagccccta
      241 agctcctcat ctatgctgca tccactttgg ccggtggggt cccatcaagg ttcagcggca
      301 gtggatctgg gacagacttc actctcacca tcagcagcct gcagcctgaa gatttgcaac
      361 ttattactgt ctacagttta aaactttccc gtacagtttt ggccagggga ccaaagtgga
      421 gatcaaacga g
//
LOCUS       KCVT01006043             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16344:15308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006043
VERSION     KCVT01006043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16344:15308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83568.1"
                     /translation="CQQYNSLPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          109 c          109 g          100 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattgagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcgttaacg tttatttaaa ttggtatcaa cagaaaccgg ggaaagcccc taagcccctg
      241 atcttttatg caaaccgttt ggaacgtggg gtcccatcaa ggttcagctg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aagttattat
      361 tgtcaacagt ataatagttt accgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006044             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8964:18162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006044
VERSION     KCVT01006044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8964:18162"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83569.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          118 c          108 g           87 t
ORIGIN      
        1 acatgggggg tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006045             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12934:17264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006045
VERSION     KCVT01006045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12934:17264"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83570.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          111 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccacatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatag aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006046             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10703:10813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006046
VERSION     KCVT01006046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10703:10813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83571.1"
                     /translation="CHQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          127 c          110 g           87 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccac cacaaacctg ggcaggctcc caagctcctc
      241 ctctatggtg catccaccag ggccaccggc atcccagaca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcaccagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006047             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22404:7585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006047
VERSION     KCVT01006047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22404:7585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83572.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          102 a          117 c          114 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 tcgag
//
LOCUS       KCVT01006048             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:18709:15721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006048
VERSION     KCVT01006048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18709:15721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..379
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83573.1"
                     /translation="CQQGYGFPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          119 c          105 g          102 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgtaggaga cacagtcgcg atcacttgcc tggcgagtca
      181 aggcattggc aataatttaa attggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatctatacg gcatccaatt tacatggtgg gattccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcaacag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatggtt ttccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01006049             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14827:14599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006049
VERSION     KCVT01006049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14827:14599"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..417
                     /note="immunoglobulin light chain variable region"
     V_region        100..417
     V_segment       100..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83574.1"
                     /translation="CQQYYTLCTF"
     J_segment       386..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          101 a          114 c          105 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gcccagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtca cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttttttaaat tggtatcagc agaagccggg gaaagcccct aaggtcctca
      241 tctattctgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagttccc tgcaacctga agattttgca acttattact
      361 gtcaacagta ttatacctta tgcacttttg gtcaggggac cacagtggag accaaacgag
//
LOCUS       KCVT01006050             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20402:8605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006050
VERSION     KCVT01006050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20402:8605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83575.1"
                     /translation="CYQHTNDYHSF"
     J_segment       383..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           96 a          128 c          109 g           88 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagag ggaaccatgg aagccccagc tcggcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaaa ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc gggggaaaga gccactctct cctgcagggc cagtcagagt
      181 gttagcagct acttagcctg gtaccaccag aaacctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccaatagggc cactggcatc ccagacaggt tcactggcag cgggtctggg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttgggtt ttatcactgc
      361 tatcagcata ccaacgacta ccacagtttt ggccaggggt ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01006051             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22080:19003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006051
VERSION     KCVT01006051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22080:19003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83576.1"
                     /translation="CQQYDSDPFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgaccc gttcactttc ggtggaggga ccaaggtaga gatcaaacga
      421 g
//
LOCUS       KCVT01006052             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22107:5419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006052
VERSION     KCVT01006052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22107:5419"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83577.1"
                     /translation="CQQQDNMPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          112 c          113 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tagggcatgg aatttggaaa caggggtccc atcaaggttc agtggaagtg gatccgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 acagcaagat aatatgccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006053             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8897:17719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006053
VERSION     KCVT01006053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8897:17719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83578.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gaacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006054             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14149:2638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006054
VERSION     KCVT01006054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14149:2638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..429
                     /note="immunoglobulin light chain variable region"
     V_region        93..429
     V_segment       93..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83579.1"
                     /translation="CGQGTHLPWTF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          100 a          120 c          117 g           95 t
ORIGIN      
        1 acatgggact gatcaggact cctcagttca ccatgaggct ccctgctcag ctcctggggc
       61 tgctattgct ctgcgtcccc ggatccagtg gggatgttgt gatgactcag tctccactct
      121 ccctgtccat cacccctgga cagccggcct ccatctcctg caggtctagt caaagccttg
      181 tacacatcaa tggaaacaca tacttgagtt ggtatcagca gaacccaggc caacctccaa
      241 ggcgcctaat ttatgaggtt tctaaccggg actctggggt cccagacaga ttcagcggca
      301 gtggggcagg gacagatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggc
      361 tttattactg cgggcaaggt acacaccttc cgtggacgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01006055             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:5537:14576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006055
VERSION     KCVT01006055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5537:14576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..322
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83580.1"
                     /translation="CMQALEFPWTF"
     J_segment       323..359
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           83 a           91 c          104 g           84 t
ORIGIN      
        1 acatggggga tccagtgggg acattgtgat gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga
      121 tggaaacacc tatttggatt ggtacctgca gaagccaggc cagtctccac acctcttgat
      181 ttatggggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct ctagagtttc cttggacgtt cggccaaggg accaaggtgg aaatcaaacg
      361 ag
//
LOCUS       KCVT01006056             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14175:3154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006056
VERSION     KCVT01006056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14175:3154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83581.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          122 c          115 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac atgttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006057             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16679:5352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006057
VERSION     KCVT01006057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16679:5352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83582.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggagtgg cacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgacgtttc cagccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccc tacagttttg gccaggggac
      421 caaagtggag atcaaacgag
//
LOCUS       KCVT01006058             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14207:19710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006058
VERSION     KCVT01006058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14207:19710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83583.1"
                     /translation="CLQGDSTPFTF"
     J_segment       389..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gaaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ctatttaagt tggtatcagc agaaaccggg aaaagctcct aagcgcctaa
      241 tctatgctgc atccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg tgatagtacc ccgttcactt ttggccaggg gaccaaagtg gacgtcaaac
      421 gag
//
LOCUS       KCVT01006059             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15291:10498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006059
VERSION     KCVT01006059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15291:10498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83584.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          112 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggagaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcaactgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acagtataac agtgacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006060             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23207:7694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006060
VERSION     KCVT01006060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23207:7694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83585.1"
                     /translation="CQQDFGWPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          120 c          118 g           88 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ctccagcaca
       61 gcttctcttc ctcctgctac tctggatccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc attctgtctt tgtctccagg ggaaagagcc accctctcct gcagggccag
      181 tcagactgtt ggcagcgcct tagcctggta ccagcagaaa cctgggcaga ctcacaaact
      241 cctcatttac ggtgcatcca gcagggccac cggcatccca gacaggttca gtggcagtgg
      301 gtctggaaca gaattcactc tcaccatcag tagtccggag cctgaggatg ttggagttta
      361 ttactgtcag caggattttg gctggcctcc gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01006061             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:3969:15715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006061
VERSION     KCVT01006061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3969:15715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..440
                     /note="immunoglobulin light chain variable region"
     V_region        104..440
     V_segment       104..403
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83586.1"
                     /translation="CMQSTKDPLTF"
     J_segment       405..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          101 a          124 c          111 g          107 t
ORIGIN      
        1 acatgggggg actgatcagg actcctcagt tcatcttctc acgatgagac tccctgctca
       61 gctcctcggg ctgttgatgc tctgggtccc tggatccagt ggcgatattt tgatgaccca
      121 gactccactc tcgctgcccg tcacccctgg agagccggcc tccatctcct gtaggtctag
      181 tcaaagcctt ctgcatagta atggatacac ctatttgcat tggtacctgc agaagccagg
      241 ccagtctcca cggctcctga tctataaagt taccaatcgc gaatctgggg tcccagacag
      301 gttcagcggc agtgggtcag gcataaattt cacactggaa atcagcaggg tggagcctga
      361 ggatgttggt gtttattact gcatgcaaag tacaaaagat cccctcactt tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01006062             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18639:6637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006062
VERSION     KCVT01006062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18639:6637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83587.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tattgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcatgg atagtgggga tgtaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccat atctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacggatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtacagttt tggccagggg
      421 accagagtgg agatcaaacg ag
//
LOCUS       KCVT01006063             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:21405:14644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006063
VERSION     KCVT01006063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21405:14644"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83588.1"
                     /translation="YQQYDKSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          117 c          113 g           85 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagggt caccatcact tgcagagcca gtcagggtat
      181 cagcaactgg ttggcctggt atcaacagaa accagggaga gcccctaacc tcctgatgta
      241 tagggcgtcc aatttgcaag gaggggtccc atcaaggttc agaggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaggat gtcgctacat attactatca
      361 acagtatgat aagtcccctc cgacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006064             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:9546:7000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006064
VERSION     KCVT01006064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9546:7000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83589.1"
                     /translation="CLQENNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          121 c          119 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcctccagc agggccactg gcatcccaga cagattcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagaataac tggtcgtaca gctttggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006065             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13969:17736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006065
VERSION     KCVT01006065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13969:17736"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..437
                     /note="immunoglobulin light chain variable region"
     V_region        102..437
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83590.1"
                     /translation="CMQALEFPRTF"
     J_segment       406..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>444
                     /gene="IGKC"
BASE COUNT           96 a          123 c          119 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg tatccagtgg tgacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgcg gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tctccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtggctca gatactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aagatgttgg gatttattac tgcatgcaag ctctagagtt tcctcggacg ttcggccagg
      421 ggaccaaggt ggaaatcgaa cgag
//
LOCUS       KCVT01006066             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21126:4075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006066
VERSION     KCVT01006066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21126:4075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83591.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01006067             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17569:13544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006067
VERSION     KCVT01006067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17569:13544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83592.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          117 c          104 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgtaactt attattgtca
      361 acaacataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01006068             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16048:20270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006068
VERSION     KCVT01006068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16048:20270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83593.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacatccg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006069             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:25438:10371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006069
VERSION     KCVT01006069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25438:10371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83594.1"
                     /translation="CQQYNGFPLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          109 c          111 g           98 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttagtagtta tttaaattgg tatcagcaga aatcggggaa agcccctgaa ctcctgatct
      241 attatgcaga ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tattactgtc
      361 aacaatataa tggttttccg ctcactttcg gtggcgggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006070             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21004:7602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006070
VERSION     KCVT01006070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21004:7602"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..278
                     /note="immunoglobulin light chain variable region"
     V_region        10..278
     V_segment       10..240
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83595.1"
                     /translation="CQQYNSDPFTF"
     J_segment       241..278
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>281
                     /gene="IGKC"
BASE COUNT           79 a           69 c           68 g           65 t
ORIGIN      
        1 acatgggaga gtaaccatca cttgtcgggc gagtcaggac ataagaagtt atttagcgtg
       61 gtatcagcag aaaccaggca aagccccgaa gcccttgatc tattacgcat ccgttttgga
      121 aagtggggtc ccatcaaggt tcagtggcag tggatctggg acagaattca ctctcaccat
      181 cagcagtctg cagcctgatg attttgcaac ttattactgt caacagtata acagtgaccc
      241 attcactttc ggccccggga ccaaactgga taccaaacga g
//
LOCUS       KCVT01006071             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14054:13273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006071
VERSION     KCVT01006071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14054:13273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83596.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          126 c          108 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcttggac agtgaggatg aaaacacgta tttggaatgg tacgtgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaacatc aacagagtgg aggctgagga
      361 tcttggaatt tattactgca tgcaagctct agaatttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01006072             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12220:14078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006072
VERSION     KCVT01006072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12220:14078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83597.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          116 c          111 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 ggatattaac aactggttgg cctggtatca acagaaacca gggaaagccc ctaaggtcct
      241 gatctatagg gcatccattt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006073             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18774:17864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006073
VERSION     KCVT01006073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18774:17864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83598.1"
                     /translation="CMQAREFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          127 c          113 g          103 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggagg ggaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgctggggtt tattactgca tgcaagctcg agagtttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01006074             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19754:10713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006074
VERSION     KCVT01006074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19754:10713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83599.1"
                     /translation="CMQSLEFPLTF"
     J_segment       405..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          122 c          113 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttaatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaaagtc tagagtttcc attgactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006075             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:10985:15894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006075
VERSION     KCVT01006075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10985:15894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..376
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83600.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       384..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          106 c          101 g          104 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca ggatggacat gacggtcccc gcttatctcc
       61 tggggctcct tctgctctgg ctcccagatg tgacatccag atgacccagt ctccatcttc
      121 cctgtctgca tctgtaggag acaaagtcac catcacttgc agggcaagtc aggacattgg
      181 taattattta aattggtatc agcagaaacc aggaaaagct cctaaggtcc tgatctatgg
      241 tgtatccaat ttacaaagtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga
      301 tcttactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt attgtcaacc
      361 gtttaaaagt tacctttcgg tccctttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006076             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16433:3057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006076
VERSION     KCVT01006076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16433:3057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..421
                     /note="immunoglobulin light chain variable region"
     V_region        104..421
     V_segment       104..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83601.1"
                     /translation="CQQGYSYHPTF"
     J_segment       391..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>428
                     /gene="IGKC"
BASE COUNT           95 a          121 c          112 g          100 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctccttggg ctcctgctgc tctggctccc aggtgccaga tgtgacttcc ttatgacgca
      121 gtctccttcc tccctgtccg catctgtagg agacacagtc accatcactt gccaggcgag
      181 tcaagccatt ggcactaatt taaattggta tcagcagaga ccaggaaaag cccctaaact
      241 cctgatctat agggcttccg gtttgcagag tgggactccc tctcggttca gcggcagtgg
      301 atctgggacg gatttcagtc tcaccatcag cagcctgcag cctgaagatt ttgccactta
      361 ttactgtcaa cagggttata gttaccatcc cactttcggc ggagggacca aggtggagat
      421 ccaacgag
//
LOCUS       KCVT01006077             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18402:13026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006077
VERSION     KCVT01006077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18402:13026"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..361
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83602.1"
                     /translation="CQQGYSYPYSF"
     J_segment       367..404
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           96 a          115 c          104 g           92 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctccttgggc tcctgctgct
       61 ctggctccca ggtgccagat gtgacatcca gatgacgcag tctccatcct ccctgtccgc
      121 atctgcagga gacacagtca ccatcacttg ccaggcgagt caaggcattg gcaatacttt
      181 aaattggtat caacagaaac cggggaaagc ccctacactc ctgatctata gggcatccgg
      241 tttgcaaagt gggactccct ctcggttcag cggcagtgga tctgggacgg atttcactct
      301 caccatcagc agcctgcagc ctgaagattt tgccacttat tactgtcaac agggttatag
      361 ttatccgtac agttttggcc aggggaccaa actggagatc aaacgag
//
LOCUS       KCVT01006078             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16392:18549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006078
VERSION     KCVT01006078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16392:18549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83603.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta cttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01006079             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:3277:10806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006079
VERSION     KCVT01006079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:3277:10806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..409
                     /note="immunoglobulin light chain variable region"
     V_region        101..409
     V_segment       101..372
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83604.1"
                     /translation="CQQNSNWPLTF"
     J_segment       373..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           99 a          122 c          109 g           82 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat acaaccggac aaatagtgct gacgcagtct
      121 ccagacaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccaggca gtgggtctgg gacagagttc
      301 actctcacca tcagcagcct ggagcctgaa gatgttgcac tttattattg tcagcagaac
      361 agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006080             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10498:12574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006080
VERSION     KCVT01006080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10498:12574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83605.1"
                     /translation="CLQESNWSYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          120 c          123 g           86 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agatagtacc ggagaaatag tggtgacaca
      121 gtctccagcc accctgtctt tgtctccagg ggaaagagcc accctctcct gcagggccag
      181 tcagagtgtc aaaagcaggt tagcctggta ccagcagaaa cctgggcaag ctcccaggct
      241 cctcatgtat gatgcgtcca gcagggccac tggcatccca gacaggttca ctggcagcgg
      301 gtctgggcca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcggttta
      361 tttctgtctt caggagagta actggtcgta cagctttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01006081             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14149:12783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006081
VERSION     KCVT01006081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14149:12783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83606.1"
                     /translation="CQQYDSDPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          118 c          108 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag cttggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattagcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga accccttgat
      241 ctatttcgca tccactttgg aaagtggcgt cccatcaagg ttcagcggca gtggacctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006082             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11462:22322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006082
VERSION     KCVT01006082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11462:22322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..366
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83607.1"
                     /translation="CLQGDTAPFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          101 a          114 c          113 g           93 t
ORIGIN      
        1 acatgggggg agaaccactc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctccttc tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcttccctgt ctgcatcggc aggagacaga gtcaccatca cttgccgggc aagtcagggc
      181 attaacgatt atttaagttg gtatcagcag aaaccaggaa aacctcctaa gcgcctgatt
      241 tatgctgcat ccagtttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcagc ttattactgt
      361 ctacagggtg atactgcccc gttcactttc ggcggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01006083             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15151:19471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006083
VERSION     KCVT01006083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15151:19471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83608.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           89 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgcgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcctctgtag gagacagtgt caccatcact tgtcgggcga gtcaggacgt
      181 tagaagttat ttggcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacgcatcc attttggaaa ctggggtccc atcaaggttc agcggcagtg gatccgggac
      301 agaattcagt ctcaccatca gcagcctgca gcctgaggac tttgcaacgt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006084             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10764:9248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006084
VERSION     KCVT01006084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10764:9248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83609.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          117 c          110 g           87 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 ggatattaac acctggttgg cctggtatca acagaagcca gggaaagccc ctaaggtcct
      241 gatctatagg acatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcaacag cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006085             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21940:8330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006085
VERSION     KCVT01006085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21940:8330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83610.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01006086             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11995:18884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006086
VERSION     KCVT01006086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11995:18884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83611.1"
                     /translation="CMQALEFPYSF"
     J_segment       404..440
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          121 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggag tggcacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgacgt ttccagccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccctacagtt ttggccaggg
      421 gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01006087             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12983:14069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006087
VERSION     KCVT01006087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12983:14069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83612.1"
                     /translation="CQKYISSPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           96 a          130 c          105 g           91 t
ORIGIN      
        1 acatgggggg ctgctcagtt aggacccaga gagaaccatg gaaatcccag ctcagcttct
       61 cttcctcctg ctactgtggc tcccaggtac caccggacaa cttatattga ctcagtctcc
      121 agccaccctg tctctgtctc caggggaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgttggcagc agcttagcct ggtaccagca gaaacctggg caggccccca ggctcctcct
      241 ctatggtgca tccagcaggg ccactggcat cccagacagg ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gattttgcag tatattactg
      361 tcagaaatat attagctccc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006088             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24727:7270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006088
VERSION     KCVT01006088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24727:7270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83613.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagc
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006089             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:3603:14299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006089
VERSION     KCVT01006089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3603:14299"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83614.1"
                     /translation="CQQHNGYPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          109 a          119 c          109 g           90 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacacagtca ccatcacttg tcgggcaagt
      181 cagggcatta cgaatgattt agcctggtat caacagaaac caggtaaagc cccgaagccc
      241 ctgatctatt acgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tattgtcaac agcataatgg ataccctccg acgttcggcc aagggaccag ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01006090             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18423:12830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006090
VERSION     KCVT01006090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18423:12830"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..424
                     /note="immunoglobulin light chain variable region"
     V_region        104..424
     V_segment       104..386
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83615.1"
                     /translation="CLQYNSSPLTF"
     J_segment       387..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          118 c          113 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acatagcatg gacatgaggg tccctgctca
       61 gttcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacacagtc accatcactt gccgggcgag
      181 tcagactatt agcagctggt tagactggta tcagcagaaa ccagggaaag cccctaacct
      241 cctgatcttt aaggcatcca gtttgcaaag tggggtcccc tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcgc ctgaagattt tgcaacttat
      361 tattgtctac agtacaatag tagcccgctc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006091             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8516:6611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006091
VERSION     KCVT01006091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8516:6611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..438
                     /note="immunoglobulin light chain variable region"
     V_region        103..438
     V_segment       103..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83616.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          114 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cgttgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggatacacct atttggaatg gtacttgcag aggccaggcc
      241 agtctccaca actcttgatt tataaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgct tatcaaacga g
//
LOCUS       KCVT01006092             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:12821:16519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006092
VERSION     KCVT01006092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12821:16519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..408
                     /note="immunoglobulin light chain variable region"
     V_region        99..408
     V_segment       99..381
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83617.1"
                     /translation="CLQGDTTPFTF"
     J_segment       388..408
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>422
                     /gene="IGKC"
BASE COUNT          102 a          118 c          108 g           94 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccggg aaaagctcct aagcgcctaa
      241 tctacctgcc tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctga
      301 gacagtgttc actctcacca tcagcagcct gcagcctgaa gattttgcga cttattactg
      361 tctacagggt gatactaccc cgttcacttt tggccagggg accaaagtag acgtcaaacg
      421 ag
//
LOCUS       KCVT01006093             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10414:16360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006093
VERSION     KCVT01006093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10414:16360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83618.1"
                     /translation="CEQYNSLPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          113 a          112 c          104 g           97 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattaa catttattta aattggtatc accagaaacc ggggaaagcc cctaagctcc
      241 tgatctatta tacaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtgaaca atacaatagt ttaccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006094             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18797:4849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006094
VERSION     KCVT01006094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18797:4849"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83619.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          119 c          119 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaagatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006095             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15980:14122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006095
VERSION     KCVT01006095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15980:14122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83620.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          108 c          106 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa accggggaaa gcccctaagt tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006096             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18746:19526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006096
VERSION     KCVT01006096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18746:19526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83621.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006097             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:22586:11476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006097
VERSION     KCVT01006097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22586:11476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83622.1"
                     /translation="CQQYNSLPYIF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          111 a          109 c          101 g           97 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 aacgtttatt taaattggta tcagcagaaa ccggggaaag cccctaaacc cctgatctat
      241 tatagaaacc gtttggaaag tggggtccca tcaaggttca gcgacagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataata gtttaccgta catttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01006098             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11968:18446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006098
VERSION     KCVT01006098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11968:18446"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..237
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83623.1"
                     /translation="CQQYDSDSLTF"
     J_segment       242..279
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>282
                     /gene="IGKC"
BASE COUNT           72 a           70 c           77 g           63 t
ORIGIN      
        1 acatgggcag agtcaccatc acttgtcggg cgactcagga cattcgcagt tatttagcgt
       61 ggtatcagca gagaccaggg aaagccccga ggcccttgat ctattacgcg tccactttgg
      121 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca
      181 tcagcagcct gcagcctgaa gattttgcaa cctattactg tcaacagtat gacagtgatt
      241 cgctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006099             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8683:16921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006099
VERSION     KCVT01006099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8683:16921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83624.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006100             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:7200:3159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006100
VERSION     KCVT01006100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7200:3159"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83625.1"
                     /translation="CQQYDSDPFTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          104 a          117 c          114 g           92 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctaggac tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgagt
      181 cagggcattc gcagttattt ggcgtggtat caccagaaac cagggaaagc cccgaagccc
      241 ttgatctatt acgcgtccag tctggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcaac agtatgacag tgacccgttc actttcggtg gagggaccaa ggtagagatc
      421 aaacgag
//
LOCUS       KCVT01006101             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15099:17168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006101
VERSION     KCVT01006101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15099:17168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83626.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006102             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8487:15823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006102
VERSION     KCVT01006102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8487:15823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83627.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          119 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagata ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006103             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6974:11790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006103
VERSION     KCVT01006103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6974:11790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83628.1"
                     /translation="CQQNDNWARTF"
     J_segment       399..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          107 a          124 c          120 g           86 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gacaccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 tagggccagt cagagtgtca gcagcagttt agcctggtac cagcagaaac ctggacaggc
      241 tcccaggctc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggc tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcaatttat tattgtcagc agaatgataa ctgggctcgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006104             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6942:10827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006104
VERSION     KCVT01006104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6942:10827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83629.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          120 c          117 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 attctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc caggcaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg agactgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01006105             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19943:5826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006105
VERSION     KCVT01006105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19943:5826"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83630.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcgcgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006106             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22675:17073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006106
VERSION     KCVT01006106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22675:17073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83631.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cggcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006107             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10816:4124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006107
VERSION     KCVT01006107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10816:4124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83632.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacgggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006108             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18481:8205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006108
VERSION     KCVT01006108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18481:8205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83633.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          125 c          116 g           84 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctctctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcctag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catgtatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006109             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7083:15656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006109
VERSION     KCVT01006109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7083:15656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83634.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 tttcgcatcc actttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006110             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13330:15219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006110
VERSION     KCVT01006110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13330:15219"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    39..359
                     /note="immunoglobulin light chain variable region"
     V_region        39..359
     V_segment       39..322
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <300..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83635.1"
                     /translation="CQQLFSHPFTF"
     J_segment       323..359
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>363
                     /gene="IGKC"
BASE COUNT           91 a           96 c           84 g           92 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggag ccagatgtga tatccagatg acccagtctc
       61 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      121 acatttatag ttattttgcg tggtatcagc agaaaccagg gaaagcccct aagctcctga
      181 tctatgctac atccagattg caaagtggga ttccctctcg cttcagcggc agtggatctg
      241 ggacagattt cactctcacc atcagcagcc tgcagcctga agattctgca tcttattact
      301 gtcaacagct ttttagtcac ccattcactt tcggccccgg gaccaaactg gatatcaaag
      361 gag
//
LOCUS       KCVT01006111             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14288:13427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006111
VERSION     KCVT01006111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14288:13427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83636.1"
                     /translation="CHQYNSLPFSF"
     J_segment       386..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          107 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttttttaaat tggtatcagc agataccggg gaaagcccct aaactcctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagagtt cgctctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaccagta taatagttta ccgttcagtt ttgcccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006112             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15016:15294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006112
VERSION     KCVT01006112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15016:15294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83637.1"
                     /translation="CMQGLQTPYTF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgcct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcacc cttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgaa tagtaatgga tacagctatt tgagttggta cctgcagagg ccaggccagt
      241 ctccacatct gctgatctat tatggctcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgaaaatcac cagggtggag gctgacgacg
      361 taggggttta ttactgcatg caaggtctac aaactccgta cacttttggc caggggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01006113             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17758:10683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006113
VERSION     KCVT01006113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17758:10683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83638.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          117 c          122 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacttgca gaaggcaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc aaactgaaca tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006114             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18597:11724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006114
VERSION     KCVT01006114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18597:11724"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83639.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          116 c          115 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 agggtattaa caactggttg gcctggtatc aacagaaacc agggaaagcc cctaaggtcc
      241 tgatctatgg ggcatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006115             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7377:19351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006115
VERSION     KCVT01006115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7377:19351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83640.1"
                     /translation="CQQYDKSPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          118 c          117 g           86 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagggtcac catcacttgc agagccagtc
      181 agggtatcag caactggttg gcctggtatc aacagaaacc agggagagcc cctaacctcc
      241 tgatgtatag ggcgtccaat ttgcaaggag gggtcccatc aaggttcaga ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaggatgtc gctacatatt
      361 actgtcaaca gtatgataag tcccctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006116             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16857:3946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006116
VERSION     KCVT01006116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16857:3946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83641.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          110 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatag aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006117             272 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:11263:18116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006117
VERSION     KCVT01006117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 272)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11263:18116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <209..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83642.1"
                     /translation="CQQHDNSPPTF"
     J_segment       235..269
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>272
                     /gene="IGKC"
BASE COUNT           76 a           65 c           70 g           61 t
ORIGIN      
        1 acatgggatc acttgcagag ccagtcaggg tattagcgac tggttggcct ggtatcaaca
       61 gaaaccaggg aaagccccta aactcctgat ctatagggca tccaatttgg aaacaggggt
      121 cccatcaagg ttcagtggaa gtggatctgg gacagatttc actctcacca tcagcagcct
      181 gcaggctgaa gatttcgcaa catatttctg tcaacagcat gataattccc ctcccacttt
      241 cggtggaggg actaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006118             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15431:3502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006118
VERSION     KCVT01006118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15431:3502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83643.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtt gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006119             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16120:15994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006119
VERSION     KCVT01006119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16120:15994"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83644.1"
                     /translation="CQQYDSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcttggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattagc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctatttc gcatccactt tggaaagtgg cgtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006120             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:2532:10360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006120
VERSION     KCVT01006120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:2532:10360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83645.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          118 c          120 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcatgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tgtggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006121             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13601:20806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006121
VERSION     KCVT01006121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13601:20806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83646.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtgtcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006122             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13907:4478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006122
VERSION     KCVT01006122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13907:4478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83647.1"
                     /translation="CMQGLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          126 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttatcactgc atgcaaggtc tagagtttcc tctcactttc ggcggaggga
      421 ccagggtgga gatcaaacga g
//
LOCUS       KCVT01006123             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17059:10863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006123
VERSION     KCVT01006123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17059:10863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83648.1"
                     /translation="CMQALEFPLTF"
     J_segment       348..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           97 c          109 g           94 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcatgtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc
      181 caggccagtc tccacagctc ttgatttatg aggtttccat acgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagt agagtggagg
      301 ctgaggatgt tgggatttat tactgcatgc aagctctaga gtttcctctc actttcggcg
      361 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006124             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14377:4282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006124
VERSION     KCVT01006124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14377:4282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83649.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          127 c          111 g           88 t
ORIGIN      
        1 acatggcgag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006125             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18673:8670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006125
VERSION     KCVT01006125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18673:8670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83650.1"
                     /translation="CQQYDSDPRTF"
     J_segment       386..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          101 a          117 c          113 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcgttcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaatc
      421 gag
//
LOCUS       KCVT01006126             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:10511:12726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006126
VERSION     KCVT01006126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10511:12726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83651.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          117 c          121 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggta gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006127             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15402:18073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006127
VERSION     KCVT01006127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15402:18073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83652.1"
                     /translation="CQQNSNRPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           97 a          122 c          116 g           88 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aattgtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag tagtttagcc tggtaccagc agagacctgg gcagcctccc aggctcctca
      241 tctatggtgc gtccagcagg gccactggca tcccagacag attcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcccga agatgttgca gtttattttt
      361 gtcagcagaa tagtaatcgg ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006128             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16773:19804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006128
VERSION     KCVT01006128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16773:19804"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83653.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaaaccaggc
      241 cagtctccac gactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006129             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10564:19198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006129
VERSION     KCVT01006129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10564:19198"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83654.1"
                     /translation="CMQALQTPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          117 c          119 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc ttgtcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg gtctctgcct ccagtggaga tatcgtgatg acccagactc
      121 cactctcgct gcccgtcaac tttggagagc cagcctccat ctcctgcagg tctagtcaga
      181 gccttctgaa tagtaacgga tacaactatt tgagttggta cctgcagagg ccaggccagt
      241 ctccacatct tctgatctat tatgcttcta gtcgggcctc cggggtcccc gacaggttca
      301 gtggcagtgg gtcaggcaca gattttacac tgaaaatcag cagggtggag gctgaggacg
      361 taggggttta ttactgcatg caagctctac aaactccgta cagttttggc caggggacca
      421 gagtggagat caaacgag
//
LOCUS       KCVT01006130             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17610:4872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006130
VERSION     KCVT01006130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17610:4872"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83655.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          120 c          107 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006131             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17744:9171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006131
VERSION     KCVT01006131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17744:9171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..320
                     /note="immunoglobulin light chain variable region"
     V_region        121..320
     V_segment       121..283
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <260..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83656.1"
                     /translation="CMQALEFPLTF"
     J_segment       284..320
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>323
                     /gene="IGKC"
BASE COUNT           70 a           85 c           92 g           76 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctcca cagctcttga tttatgaggt ttccaagcgg gcctctggag tcccagacag
      181 gttcagtggc agtgggtcag gcactgattt cacactgaaa atcagcagag tggaggctga
      241 ggatgttggg gtttatcact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      301 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01006132             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14237:20627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006132
VERSION     KCVT01006132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14237:20627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83657.1"
                     /translation="CLQGYSVPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          117 c          107 g           98 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcttcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcgat tatttaagtt ggtatcagca gagaccagga aaaactcctc agcgcctgat
      241 ctatgctgca tccagtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcag cttattactg
      361 tctacagggt tatagtgtcc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006133             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12149:15425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006133
VERSION     KCVT01006133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12149:15425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83658.1"
                     /translation="CQQYDSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          106 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccgggcta gtcaggacat
      181 tagtaatttt ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatggaaac cgtttgggaa gcggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgacgat tttgcgactt atcattgtca
      361 gcagtatgat agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006134             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20801:15612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006134
VERSION     KCVT01006134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20801:15612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83659.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgcgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaag tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaggt cagcagagtg gaggctgagg
      361 atgtcggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006135             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13520:23624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006135
VERSION     KCVT01006135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13520:23624"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83660.1"
                     /translation="CEQYNSLPYTF"
     J_segment       406..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          118 a          115 c          110 g          103 t
ORIGIN      
        1 acatggggag gctggacaga cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag gtgccagatg
      121 tgacattcag atgacccagt ctccatcctc cctgtctgct tctgtaggag acagagtcac
      181 catcacttgc cgggcaagtc aggacattaa catttattta aattggtatc accagaaacc
      241 ggggaaagcc cctaagctcc tgatttatta tacaaatcgt ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc
      361 tgaagatttt gcaacttatt actgtgaaca atacaatagt ttaccgtaca cttttggcca
      421 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01006136             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9366:11270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006136
VERSION     KCVT01006136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9366:11270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83661.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006137             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21540:14022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006137
VERSION     KCVT01006137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21540:14022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83662.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcaacttag cctggtacca gcagagacct gggcagtctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006138             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8631:6474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006138
VERSION     KCVT01006138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8631:6474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83663.1"
                     /translation="CLQDIQLPLTF"
     J_segment       399..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           89 a          123 c          121 g          106 t
ORIGIN      
        1 acatgggagg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctggggctgc tggtgctctg gctccctggg accagtgggg atattatgat gactcagact
      121 ccactctccc tgtccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgc ataggaatgg gtacacctat ttgttttggt acctgcagaa gccaggccag
      241 tctccacagc tcctgatcta tttcggttcc aaccgggcct ctggagtccc agacaggttc
      301 agtgccagtg ggtcaggcac tgatttcaca ctgaaaatca gccgggtgga ggctgaggat
      361 gttggggttt attactgctt gcaagatata caacttccgc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01006139             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:20449:13794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006139
VERSION     KCVT01006139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20449:13794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83664.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          110 c          103 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaat tatttaaatt ggtatcagca gaaaccgggg aaagccccta agctcctgat
      241 ctattatgta aaccatttgg aaagtggggt cccatcaacg ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct ccaacctgaa gattttgcaa cttattactg
      361 tcaacaatat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006140             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13756:14182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006140
VERSION     KCVT01006140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13756:14182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83665.1"
                     /translation="CQQHDNFPYIF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          110 a          115 c          101 g           92 t
ORIGIN      
        1 acatgggagt ctcagacagg acacagcatg gacacgaggg tccccgctca gctcctgggg
       61 ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag tcaacatatt
      181 agcgactggt tggcctggta tcaacagaaa ccagggaaag cccctaagct cctgatctat
      241 cgggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg atctgggaca
      301 gatttcactc tcaccatcag cagctttcag cctgaagata tcgcaacata ttactgtcaa
      361 cagcatgata atttcccgta catttttgac caggggacca aactggagat caaacgag
//
LOCUS       KCVT01006141             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:26390:22072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006141
VERSION     KCVT01006141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26390:22072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83666.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          118 c          107 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01006142             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9282:5107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006142
VERSION     KCVT01006142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9282:5107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83667.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          125 c          117 g           86 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccaacaaaaa cctgggcagg ctcccaggct
      241 cctcatctat ggtgcatcca gcagggccac tggcatccca gacaggttca gtggcagtgg
      301 gtctgggacg gacttcactc tcaccatcac cagcctggag cctgaagatg ttgcagtcta
      361 tttttgtcag cagaatagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01006143             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:5864:6441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006143
VERSION     KCVT01006143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:5864:6441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83668.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          123 c          119 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgta tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgcgga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccagggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006144             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:26174:11696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006144
VERSION     KCVT01006144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26174:11696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83669.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc aacagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006145             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13727:15877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006145
VERSION     KCVT01006145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13727:15877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83670.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          121 c          123 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006146             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15961:17868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006146
VERSION     KCVT01006146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15961:17868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83671.1"
                     /translation="CMQALDFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttttgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagtgt ggaggctgag
      361 gatgttgggg tctattactg catgcaagct ctagactttc cttacagttt tggccagggg
      421 accaaagtgg agattaaacg ag
//
LOCUS       KCVT01006147             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9003:6105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006147
VERSION     KCVT01006147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9003:6105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83672.1"
                     /translation="CQQYNSLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          104 a          111 c          108 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gggacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtcaattt ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat agtttgcctc ggacgttcgg ccaagggacc aaggtggaaa tcagtcgag
//
LOCUS       KCVT01006148             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12113:19260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006148
VERSION     KCVT01006148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12113:19260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83673.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          118 c          127 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acgtagtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag tcggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctggg
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006149             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10521:3437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006149
VERSION     KCVT01006149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10521:3437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83674.1"
                     /translation="CQQYNSYPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          106 g           97 t
ORIGIN      
        1 acatggggga atcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca gttatttagc ctggtatcag cagaaaccag ggaaagcccc taagcgcctg
      241 atctatgctg catccacttt gcaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gtgacagatt tcactctcac catcagcagc ctacagcctg aagattttgc aacttattac
      361 tgtcaacagt ataatagtta tccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006150             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11409:19311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006150
VERSION     KCVT01006150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11409:19311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83675.1"
                     /translation="CQQGYSYPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccct
      121 cctccctgtc cgcatctgta ggagacgcag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcaataa tttaaattgg tttcagcaga aaccagggaa agcccctaaa ctcctgatct
      241 ataagacatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttacccg tggacgttcg gccaaggggc caaggtggag atcaaacgag
//
LOCUS       KCVT01006151             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:25668:4280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006151
VERSION     KCVT01006151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25668:4280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..379
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83676.1"
                     /translation="CQQGYSYPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          120 c          107 g           95 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctataggaga cacagtcacc atcacttgcc aggcgagtca
      181 aggcattgac aataatttaa attggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatctttggg gcatccactt tccaaagtgg gactccctcg cggttcagcg gcagtgaatc
      301 tgggacggat ttcactctca ccatcagcag cctgcagcct gaagattttg ccacttattt
      361 ctgtcaacag ggttatagtt accctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006152             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:5031:12144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006152
VERSION     KCVT01006152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:5031:12144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83677.1"
                     /translation="CQQYDSDSLSF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          114 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctggagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcag tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006153             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13379:5878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006153
VERSION     KCVT01006153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13379:5878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83678.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          123 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagc caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006154             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10222:8833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006154
VERSION     KCVT01006154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10222:8833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83679.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          105 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgatttt tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttgggattt attactgcat gcaagctcta gagtttcctt ggacgttcgg ccaagggacc
      421 agggtggaaa tcaaacgag
//
LOCUS       KCVT01006155             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14006:13572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006155
VERSION     KCVT01006155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14006:13572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83680.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006156             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9278:8667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006156
VERSION     KCVT01006156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9278:8667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83681.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01006157             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14684:5676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006157
VERSION     KCVT01006157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14684:5676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83682.1"
                     /translation="FQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tttcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01006158             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:11131:3981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006158
VERSION     KCVT01006158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11131:3981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83683.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttggcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006159             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5359:8917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006159
VERSION     KCVT01006159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5359:8917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..348
                     /note="immunoglobulin light chain variable region"
     V_region        9..348
     V_segment       9..310
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83684.1"
                     /translation="CMQALEFPYSF"
     J_segment       312..348
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           82 a           90 c           98 g           81 t
ORIGIN      
        1 acatggggga cattgtgatg acccagactc cactctccct gcccgtcacc cttggagagc
       61 cggcctccat ctcctgcagg tctagtcaga gcctcttgga tagtgaggat ggaaacacct
      121 atttggagtg gcacctgcag aagccaggcc agtctccaca actcttgatt tatgacgttt
      181 ccagccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      241 cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaagctc
      301 tagagtttcc ctacagtttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006160             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10949:7835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006160
VERSION     KCVT01006160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10949:7835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83685.1"
                     /translation="CQQDFDWPPTF"
     J_segment       272..306
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>309
                     /gene="IGKC"
BASE COUNT           70 a           91 c           84 g           64 t
ORIGIN      
        1 acatgggagc caccctgtct ttgtctccag gggaaagagc caccctctcc tgcagggcca
       61 gtcagagtgt tggcaacacc ttaacctggt accagcacaa acctgggcag gctcccaagc
      121 tcctcctcta tggtgcatcc accagggcct ccggcatccc aggcaggttc agtgccagtg
      181 ggtctggaac agagtttact ctcaccatca gcagcctgga gcctgaagat gttggaattt
      241 attactgtca gcaggatttt gactggcctc cgacgttcgg ccaagggacc aaggtggaga
      301 tcaaacgag
//
LOCUS       KCVT01006161             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21952:15015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006161
VERSION     KCVT01006161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21952:15015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83686.1"
                     /translation="CQQGNSNPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          111 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtttcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggc
      181 cattagcagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aactcctgat
      241 atactatgga aaaagtttgg caagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcaccagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagggt aatagtaatc ctctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006162             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6676:14450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006162
VERSION     KCVT01006162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6676:14450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83687.1"
                     /translation="CMQSLELPFTF"
     J_segment       265..302
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           72 a           72 c           88 g           73 t
ORIGIN      
        1 acatggggga gagccggcgt ccatctcctg taggtctagt cagagcctcg tggatagtga
       61 ggatggaaac acctatttgg aatggttcct gcagaggcca ggccagtctc cacagctctt
      121 gatttatgac gtttccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      181 agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg gggtttatta
      241 ctgcatgcaa tctctagagc ttccattcac tttcggcccg gggaccaaac tggatatcaa
      301 acgag
//
LOCUS       KCVT01006163             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11435:16530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006163
VERSION     KCVT01006163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11435:16530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83688.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gagactgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006164             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11360:3715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006164
VERSION     KCVT01006164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11360:3715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83689.1"
                     /translation="CLQYKTYPFTF"
     J_segment       386..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          105 g          101 t
ORIGIN      
        1 acatgggggg gagtcagaca cagtcaggac acagcatgga catgagggcc cccgctcatc
       61 tcctagggct cttgctgctc tggctcccag gtgccagatg tgacatccag atgactcagt
      121 ctccatcttc cctgtctgca tctgcaggag acactgtcac catcacttgc cgggcaagtc
      181 agggtattgg gacctattta aattggtttc agcagaaacc agggaaagcc cctaagctcc
      241 tgatctatgc tgcatctagt ctggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ttgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtctaca gtataaaact tatccattca ccttcggccc cgggaccaaa ctggatatca
      421 aaggag
//
LOCUS       KCVT01006165             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:4775:14675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006165
VERSION     KCVT01006165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4775:14675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83690.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          121 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaca aaccaggcca
      241 gtctccagag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggctt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag gtcaaacgag
//
LOCUS       KCVT01006166             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22243:13407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006166
VERSION     KCVT01006166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22243:13407"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..386
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83691.1"
                     /translation="CQQHNSYPRTF"
     J_segment       388..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT          106 a          117 c          111 g           92 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtaccagatg tgacatccag atgacccagt
      121 ctccatcttc cttgtctgca tctgtaggag acagagtcac catcacttgc caagccagtc
      181 agggtattgg caactggtta gcctggtatc ggcagaaacc agggaaagcc cctaagctcc
      241 tgatctatgc tgcatccagt ttacaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcagca gcataatagt tatcctcgga cgttcggcca agggaccaag gtggaaatca
      421 agcgag
//
LOCUS       KCVT01006167             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10904:14539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006167
VERSION     KCVT01006167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10904:14539"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83692.1"
                     /translation="CQQGYRYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          115 c          108 g           99 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acgcagtctc
      121 catcctccct gtccgcatct gtgggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattgacat taatttaaat tactatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atcccgtttg gaaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatcgttac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006168             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6075:3092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006168
VERSION     KCVT01006168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6075:3092"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83693.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          125 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggtt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01006169             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11147:11079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006169
VERSION     KCVT01006169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11147:11079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83694.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          124 c          112 g           86 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006170             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17494:14267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006170
VERSION     KCVT01006170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17494:14267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83695.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           94 a          123 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01006171             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9826:8695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006171
VERSION     KCVT01006171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9826:8695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83696.1"
                     /translation="CQQYNSDWRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          114 g           92 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg actggcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006172             359 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23109:18634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006172
VERSION     KCVT01006172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23109:18634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..356
                     /note="immunoglobulin light chain variable region"
     V_region        110..356
     V_segment       110..314
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>328
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83697.1"
                     /translation="CQQYDSDSLTF"
     J_segment       319..356
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        357..>359
                     /gene="IGKC"
BASE COUNT           92 a           95 c           95 g           77 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagagaccca gtcaggacat
      121 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      181 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      241 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      301 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006173             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16305:17588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006173
VERSION     KCVT01006173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16305:17588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83698.1"
                     /translation="CQQYNSLPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          114 c          107 g          101 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattag tagttattta aattggtatc agcagaaacc ggggaaagcc cctaaggtcc
      241 tgatctatta tgtcgaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 tctgtcaaca gtataatagt ttaccattca ctttcggccc cgggaccaaa ctggatctca
      421 aacgag
//
LOCUS       KCVT01006174             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15307:2139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006174
VERSION     KCVT01006174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15307:2139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83699.1"
                     /translation="CQQYNSDPRTF"
     J_segment       409..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          123 c          119 g           95 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgagtc agggcattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtataacagt gacccgcgca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01006175             548 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6932:7898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006175
VERSION     KCVT01006175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 548)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6932:7898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    224..545
                     /note="immunoglobulin light chain variable region"
     V_region        224..545
     V_segment       224..503
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <485..>517
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83700.1"
                     /translation="CQQYDSDSLTF"
     J_segment       508..545
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        546..>548
                     /gene="IGKC"
BASE COUNT          136 a          139 c          136 g          137 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt aaggaaggga acattagaag tttacctaag
      121 ccagtgagct cagtactgcc tgccttttca gggaagttct cttactacat gattaattat
      181 ctggacattt gtttttatgt ttccaatctc aggtgccaaa tgtgacatcc agatgaccca
      241 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      301 tcaggacatt cgcagttatt tagcgtggta tcagcagaga ccagggaaag ccccgaagcc
      361 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      421 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      481 ttactgtcaa cagtatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      541 caaacgag
//
LOCUS       KCVT01006176             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20713:10031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006176
VERSION     KCVT01006176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20713:10031"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..419
                     /note="immunoglobulin light chain variable region"
     V_region        95..419
     V_segment       95..375
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83701.1"
                     /translation="CLQYSSSLPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          106 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcga gtcagactat
      181 tagttactgg ttaaactggt atcagcagaa accaggaaaa gcccctaaac tcctgatcta
      241 taaggcgtcc agtttgcaac ctggggtccc atcaagtttc agcggcagtg gatctgggag
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgttt
      361 acaatatagc agtagtcttc cactcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006177             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16830:7256
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006177
VERSION     KCVT01006177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16830:7256"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83702.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctccaga agccaggcca
      241 gtctccacat ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaggggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006178             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:19234:5607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006178
VERSION     KCVT01006178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19234:5607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83703.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccaat ggggatgttc tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtgcacacca ctggaaacac atacttgagt tggtatcaac agaggccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gattctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcggag tggaggctga ggatgttgga
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01006179             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:23488:5949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006179
VERSION     KCVT01006179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23488:5949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83704.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctacatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01006180             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:24323:9431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006180
VERSION     KCVT01006180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24323:9431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83705.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggccccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat tcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccgt ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct ttttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtgt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaagtgga aatcaaacga g
//
LOCUS       KCVT01006181             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18581:6624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006181
VERSION     KCVT01006181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18581:6624"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..281
                     /note="immunoglobulin light chain variable region"
     V_region        5..281
     V_segment       5..234
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83706.1"
                     /translation="CQQHNNYSPTF"
     J_segment       247..281
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>284
                     /gene="IGKC"
BASE COUNT           79 a           71 c           70 g           64 t
ORIGIN      
        1 acatggggac acagtcacca tcacttgtcg ggcaagtcag ggcattagca atgatttagt
       61 ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg atctattacg catccaattt
      121 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      181 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagc ataataatta
      241 ctctcccact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006182             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19068:3273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006182
VERSION     KCVT01006182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19068:3273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83707.1"
                     /translation="CQQGHTFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           95 a          122 c          104 g           98 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt tacgatcact tgccaggcga gtcaaggcat
      181 tggcaagact ttaagttggt atcagcagaa accagggaaa gcccctaatc tcctgatcta
      241 tagggcatcc agtttgcaag gtggcattcc ctctcggttc agcggcggtg gctctgggac
      301 gaatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcat actttcccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006183             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14624:9809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006183
VERSION     KCVT01006183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14624:9809"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83708.1"
                     /translation="CQQHADSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          118 c          111 g           89 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggtattagca actggttggc ctggtatcaa cagagaccag ggaaagcccc taaggtcctg
      241 atttatagga catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aaccggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc tacatattac
      361 tgtcaacagc atgctgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006184             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22542:7023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006184
VERSION     KCVT01006184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22542:7023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..413
                     /note="immunoglobulin light chain variable region"
     V_region        96..413
     V_segment       96..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83709.1"
                     /translation="CQQYYTLCTF"
     J_segment       382..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          101 a          112 c          103 g          100 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgccc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtcacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtagtttt ttaaattggt atcaacagaa gccggggaaa gcccctaagg tcctcatcta
      241 ttctgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gttccctgca acctgaagat tttgcaactt attactgtca
      361 acagtattat actttatgca cttttggcca ggggaccaca gtggagatca aacgag
//
LOCUS       KCVT01006185             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8784:10222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006185
VERSION     KCVT01006185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8784:10222"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83710.1"
                     /translation="CQQYDSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          113 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cactcagctc
       61 ctaggactcc tgctgctctg tctcccaggc gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006186             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18643:10274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006186
VERSION     KCVT01006186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18643:10274"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83711.1"
                     /translation="CQQYDSFPLTF"
     J_segment       387..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          118 c          109 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtgggaga cagagtcacc atcacttgcc gggctagtca
      181 ggacattagt aattttttaa attggtatca gcagaaaccg gggaaagccc ctaagctcct
      241 gatctattat ggaaaccgtt tgggaagcgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gacgattttg cgacttatca
      361 ttgtcagcag tatgatagtt tccccctcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01006187             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21821:3936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006187
VERSION     KCVT01006187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21821:3936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..365
                     /note="immunoglobulin light chain variable region"
     V_region        88..365
     V_segment       88..323
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83712.1"
                     /translation="CQQYDSDSLTF"
     J_segment       328..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           93 a           97 c           99 g           79 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg agacagagtc accatcactt gtcgggcgac
      121 tcaggacatt cgcagttatt tagcgtggta tcaacagaaa ccagggaaag ccccgaggcc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01006188             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14226:15172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006188
VERSION     KCVT01006188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14226:15172"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83713.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccaa agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006189             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11664:3555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006189
VERSION     KCVT01006189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11664:3555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83714.1"
                     /translation="CQQHDNMPLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          108 a          115 c          117 g           88 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtggg agacagagtc accatcactt gcagggccag
      181 tcagggtatt agcaactggt tggcctggta tcaacagaaa ccagggaaag cccctaagct
      241 cctgatctat agggcatgga atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atccgggaca gatttcactc tcaccatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgata atatgccgct cactttcggt ggagggacca aggtggacat
      421 caaacgag
//
LOCUS       KCVT01006190             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6013:4515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006190
VERSION     KCVT01006190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6013:4515"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..444
                     /note="immunoglobulin light chain variable region"
     V_region        105..444
     V_segment       105..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83715.1"
                     /translation="CMQALEFPWTF"
     J_segment       407..444
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT           97 a          122 c          125 g          103 t
ORIGIN      
        1 acatgggggt gactgatcac gactcctcag gtcaccttct cacaatgagg ctccctgctc
       61 agctcctggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
      121 agactccact ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta
      181 gtcagagcct cttggatggt gaggatggaa acacctattt ggagtggcac ctgcagaagc
      241 caggccagtc tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      301 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      361 ctgaggatct tggggtttat tactgcatgc aagctctaga gtttccgtgg acgttcggcc
      421 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01006191             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:7473:15538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006191
VERSION     KCVT01006191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7473:15538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83716.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatgtca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006192             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20200:14704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006192
VERSION     KCVT01006192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20200:14704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83717.1"
                     /translation="CQQYNSLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          111 c          106 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat agtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01006193             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6315:17061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006193
VERSION     KCVT01006193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6315:17061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83718.1"
                     /translation="CLQGYSPPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          116 c          108 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa agccctgagc gcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc ggcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaggtt atttctgtct
      361 acagggttat agtcccccat tcactttcgg ccccgggacc aaactggatt tcaaacgag
//
LOCUS       KCVT01006194             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14459:20676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006194
VERSION     KCVT01006194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14459:20676"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83719.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006195             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11904:8365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006195
VERSION     KCVT01006195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11904:8365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83720.1"
                     /translation="CQQYDNDPYNF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          113 c          109 g           91 t
ORIGIN      
        1 acatgggggg agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagccaggac
      181 attaggagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa ggccttgatc
      241 tattacacat ccgttttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgatg atcttgcaac ttattactgt
      361 caacagtatg acaatgaccc gtacaatttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01006196             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10581:18687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006196
VERSION     KCVT01006196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10581:18687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83721.1"
                     /translation="CQQHDNAPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          109 a          117 c          116 g           85 t
ORIGIN      
        1 acatggggca ggagtcagtc tcagacagga cacagcatgg acacgagggt ccccgctcag
       61 ctcctggggc tcctgttgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg cagagccagt
      181 cagagtatta acgactggtt ggcctggtat caacagagac cagggaaggc ccctaagctc
      241 ctgatctata gggcatccaa tttggaaaca ggggtcccat caaggttcag tggaagtgga
      301 tctgggacag atttcactct cagcatcagc agcctgcagc ctgaagatat cgcaacatat
      361 tactgtcagc agcatgacaa tgccccgtgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01006197             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:3245:9146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006197
VERSION     KCVT01006197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3245:9146"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83722.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          100 a          121 c          113 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagactc
      121 cactgtcgct gcccgtcacc cctggagagc cggcctctat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01006198             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25802:15009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006198
VERSION     KCVT01006198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25802:15009"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..435
                     /note="immunoglobulin light chain variable region"
     V_region        114..435
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83723.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          105 a          125 c          121 g           87 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag
      121 tgatgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagcg tagcctggta ccagcaaaaa cctgggcagg
      241 ctcccagact cctcatctat ggtgcatcca acagggccac tggcatccca gacaggttca
      301 gtggcagtgg gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg
      361 ttgcacttta ttattgtcag cagaatagta actggcctct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01006199             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13684:10473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006199
VERSION     KCVT01006199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13684:10473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83724.1"
                     /translation="CLQGYIDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          111 c          110 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gcttcttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtcg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006200             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15053:9430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006200
VERSION     KCVT01006200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15053:9430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..372
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83725.1"
                     /translation="CEQYNSLPYTF"
     J_segment       373..410
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          109 a          109 c           99 g           96 t
ORIGIN      
        1 acatgggcag tcaggacaca gcatggacat gagggtcccc gctcagctcc tggggctcct
       61 gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc catcctccct
      121 gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg acattaacat
      181 ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga tctattatac
      241 aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcaacctga agattttgca acttattact gtgaacaata
      361 caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac gag
//
LOCUS       KCVT01006201             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:3505:8747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006201
VERSION     KCVT01006201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3505:8747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83726.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctccc
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006202             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8857:4406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006202
VERSION     KCVT01006202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8857:4406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83727.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcaa aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgcaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaagcga g
//
LOCUS       KCVT01006203             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:5957:8625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006203
VERSION     KCVT01006203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5957:8625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..367
                     /note="immunoglobulin light chain variable region"
     V_region        87..367
     V_segment       87..327
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83728.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       335..367
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT          100 a           89 c           93 g           88 t
ORIGIN      
        1 acatggggaa gtcagaacca ctcaggacac aggatggaca tgacggtccc cgcttatctc
       61 ctggggctcc ttctgctctg gctcccagga gacaaagtca ccatcacttg cagggcaagt
      121 caggacattg gtaattattt aaattggtat cagcagaaac caggaaaagc tcctaaggtc
      181 ctgatctatg gtgtatccaa tttacaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag atcttactct caccatcagc agcctgcagc ctgaagattt tgcaacgtat
      301 tattgtcaaa cgtttaaaag ttacctttcg gtccctttcg gcggagggac caaggtggag
      361 atcaaacgag
//
LOCUS       KCVT01006204             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22377:19612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006204
VERSION     KCVT01006204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22377:19612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83729.1"
                     /translation="CQQYNSLPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          108 c          109 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattgagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcgttaacgt ttatttaaat tggtatcaac agaaaccggg gaaagcccct aagcccctga
      241 tcttttatgc aaaccgtttg gaacgtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacttga agattttgca agttattatt
      361 gtcaacagta taatagttta ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006205             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:25716:8111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006205
VERSION     KCVT01006205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25716:8111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..384
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83730.1"
                     /translation="CQQRNSYPYVYSF"
     J_segment       390..428
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          103 a          112 c          114 g          102 t
ORIGIN      
        1 acatgggggg agttagaccc agtctggacg cagcatggac atcagggtcc tcgctcagct
       61 tctcgggctc cttctgctct ggctcccagg tgccagatgt gacattcagt tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcaagtca
      181 ggacattggc agttatttag cctggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatctataag gcgtccagtt tgcaaactgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctga ccatcagcag cctgcaggct gaagattttg cagtttatta
      361 ctgtcaacag cgtaatagtt acccgtacgt gtacagtttt ggccagggga ccaaagtgga
      421 gatcaaacga g
//
LOCUS       KCVT01006206             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21385:9824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006206
VERSION     KCVT01006206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21385:9824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83731.1"
                     /translation="CQQYSSYPFTF"
     J_segment       381..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          117 c          105 g           96 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagttcctg
       61 gggctcctgc tgctctggat cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaaa gtcaccatca cttgccgagc cagtcagggt
      181 attagcagct tgttagcctg gtatcagcag aaaccaggga aagcccctaa gtccctgatc
      241 tataaggcat ccagtttgca aagtggggtc ccttcaaggt tcagcggcag tggatctggg
      301 acagatttca ctctcagcat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtata gtagttaccc attcactttc ggccccggga ccaaactgga tatcaaacga
      421 g
//
LOCUS       KCVT01006207             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:25234:6339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006207
VERSION     KCVT01006207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25234:6339"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83732.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          106 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accggggaaa gtccctgagc tcctgatcta
      241 tgctgcatcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006208             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12085:23136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006208
VERSION     KCVT01006208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12085:23136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..285
                     /note="immunoglobulin light chain variable region"
     V_region        9..285
     V_segment       9..248
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83733.1"
                     /translation="CQQHDNSPPTF"
     J_segment       251..285
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           79 a           72 c           78 g           59 t
ORIGIN      
        1 acatgggggg agacagagtc accatcactt gcagagccag tcagggtgtt agcgactggt
       61 tggcctggta tcaacagaga ccagggaaag cccctaaact cctgatctat agggcgtcca
      121 atttggatac aggggtccca tcaaggttca gtggaagtgg atctgggaca gatttcactc
      181 tcaccatcag cagcctgcag cctgaagata tcgctacata ttactgtcaa cagcatgata
      241 attcccctcc gacgttcggc caagggacca aggtggagat caaacgag
//
LOCUS       KCVT01006209             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14284:13471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006209
VERSION     KCVT01006209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14284:13471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83734.1"
                     /translation="CQQNDNWARTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          122 c          115 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag acaccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgt agggccagtc
      181 agagtgtcag cagcagttta gcctggtacc agcagaaacc tggacaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtggct
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcaatttatt
      361 attgtcagca gaatgataac tgggctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006210             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10768:10462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006210
VERSION     KCVT01006210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10768:10462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83735.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          125 c          118 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tactgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaga cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01006211             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:12846:3738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006211
VERSION     KCVT01006211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12846:3738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83736.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtgcc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006212             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10189:20948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006212
VERSION     KCVT01006212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10189:20948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83737.1"
                     /translation="CMQALEFPWTF"
     J_segment       265..302
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           74 a           68 c           92 g           71 t
ORIGIN      
        1 acatggggga gagccggcct ccatctcctg caggtctagt cagagtctct tggatagtga
       61 ggatggaaac acctatttgg aatggtacct gcagaagcca ggccagtctc cacagctctt
      121 gatttatgag gtttccaacc gggcctctgg agtcccagac aggttcagtg gcggtgggtc
      181 agacactgat ttcacactga aaatcagcag agtggaggct gatgatgttg gggtttatta
      241 ctgcatgcaa gctctagagt ttccgtggac gttcggccaa gggaccaagg tggaaatcaa
      301 acgag
//
LOCUS       KCVT01006213             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17642:1818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006213
VERSION     KCVT01006213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17642:1818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83738.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           86 t
ORIGIN      
        1 acatgggggg ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006214             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:24451:12402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006214
VERSION     KCVT01006214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24451:12402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83739.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          120 g          108 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccaaagtgga gattaaacga g
//
LOCUS       KCVT01006215             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21589:12860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006215
VERSION     KCVT01006215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21589:12860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83740.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          118 c          106 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006216             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16386:4787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006216
VERSION     KCVT01006216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16386:4787"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83741.1"
                     /translation="CQQYNSDPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          116 c          106 g           95 t
ORIGIN      
        1 acatgggggg gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac tatcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaagcc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      421 aacgag
//
LOCUS       KCVT01006217             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15557:15263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006217
VERSION     KCVT01006217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15557:15263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83742.1"
                     /translation="CQHSFRSPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          116 c          107 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccgtcact tgcagggcta gtgagagcgt
      181 tagcaccaaa ttacattggt atcaacagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctggaac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt tttactgtca
      361 gcatagtttt cgttccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006218             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14579:11401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006218
VERSION     KCVT01006218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14579:11401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83743.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct acttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgactttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006219             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6046:10351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006219
VERSION     KCVT01006219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6046:10351"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83744.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          125 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcgcc cttggagagc cggcctccat ctcctgcagg tccagtcaga
      181 gcctcgtgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc atctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006220             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4683:6571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006220
VERSION     KCVT01006220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4683:6571"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83745.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcacaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006221             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10421:3759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006221
VERSION     KCVT01006221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10421:3759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..373
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83746.1"
                     /translation="CLQGYNIPYNF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          110 c          113 g           99 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacatcc agttgaccca
      121 gtctccatct tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt agcgattatt taagttggta tcagcagaaa ccaggaaaag ctcctaagcg
      241 cctgatctat gctgtgtcca gtttggaagg tggggtccca tcaagattca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcgactta
      361 ttactgtcta cagggttata atatcccgta caattttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01006222             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:12504:18811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006222
VERSION     KCVT01006222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12504:18811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83747.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggtg cagatcaaac
      421 gag
//
LOCUS       KCVT01006223             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6060:13980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006223
VERSION     KCVT01006223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6060:13980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83748.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccattggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggttcctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01006224             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:7755:24246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006224
VERSION     KCVT01006224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7755:24246"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83749.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 taagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01006225             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:25555:11144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006225
VERSION     KCVT01006225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25555:11144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83750.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006226             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15330:3870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006226
VERSION     KCVT01006226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15330:3870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83751.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          115 c          126 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ctagtgggga tgttgtgatg acccagagtc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gcccttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006227             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22813:3818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006227
VERSION     KCVT01006227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22813:3818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83752.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccagttt ggaaagtggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcagtggag ggaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01006228             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14155:19362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006228
VERSION     KCVT01006228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14155:19362"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83753.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaagatt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgactcg ctcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01006229             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11203:9441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006229
VERSION     KCVT01006229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11203:9441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83754.1"
                     /translation="CQQHDNSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          120 c          106 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaatat ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt caccctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgataattcc cctcggacgt tcggccaagg gaccaaggtg gaagtcaaac
      421 gag
//
LOCUS       KCVT01006230             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13895:13335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006230
VERSION     KCVT01006230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13895:13335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83755.1"
                     /translation="CQQYNNDPPTF"
     J_segment       388..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          123 c          105 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattggc agtcatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagac ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacaatg accctcccac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01006231             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14149:10375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006231
VERSION     KCVT01006231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14149:10375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83756.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           91 a          118 c          124 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcgccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga ggccaggcca
      241 gtctccacag ctgttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatttctgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa ttcaaacgag
//
LOCUS       KCVT01006232             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25896:20119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006232
VERSION     KCVT01006232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25896:20119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83757.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           86 t
ORIGIN      
        1 catggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtctatttt
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006233             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:14492:7932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006233
VERSION     KCVT01006233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14492:7932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83758.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006234             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13200:15204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006234
VERSION     KCVT01006234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13200:15204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83759.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gctcctgcag aagccaggcc
      241 agtctctaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006235             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7023:17703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006235
VERSION     KCVT01006235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7023:17703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83760.1"
                     /translation="CQQYNGFPWTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT          105 a          110 c          111 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcattagt ttttatttaa attggtatca gcagaaaccg gggaaagccc ctaacctcct
      241 gatctattat acaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcaatctca ccatcagcag cctacagcct gaggattttg caacttattg
      361 ctgtcaacag tataatggtt ttccgtggac gttcggccaa gggaccaagg tggaaatcat
      421 acgag
//
LOCUS       KCVT01006236             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24723:5132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006236
VERSION     KCVT01006236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24723:5132"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83761.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          112 c          101 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006237             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16503:15751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006237
VERSION     KCVT01006237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16503:15751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83762.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          117 c          120 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcactct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa accaggccag
      241 tctccacgac tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01006238             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21155:19578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006238
VERSION     KCVT01006238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21155:19578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83763.1"
                     /translation="CQQYNSLPYSF"
     J_segment       307..344
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           94 a           84 c           84 g           85 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgacccag tctccatctt ccctgtctgc
       61 ttctgtagga gacagagtca ccatcacttg ccgggcaagt caggacatta gcagtttttt
      121 aaattggtat cagcagaaac cggggaaagc ccctaaggcc ctgatctatt atgcaaaccg
      181 gttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcagc agcctgcaat ctgaagattt tgcaacttat tactgtcaac agtataatag
      301 tttaccgtac agttttggcc aggggaccaa agtagagatc aaacgag
//
LOCUS       KCVT01006239             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18136:16930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006239
VERSION     KCVT01006239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18136:16930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..428
                     /note="immunoglobulin light chain variable region"
     V_region        92..428
     V_segment       92..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83764.1"
                     /translation="CGQGTQLPPTF"
     J_segment       395..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          102 a          120 c          115 g           94 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gattcagtgg ggatattgtg atgactcagt ctccactctc
      121 cctgcccatc acccctggac agccggcctc catctcctgc aggtctagtc aaagccttgt
      181 acacatcaat ggaaacacat acttgagttg gtatcaccag aagccaggcc aacctccaag
      241 gcgcctaatt tatgaggttt ctaaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcaggg acagatttca cactgaaaat cagcagagtg gaggctgagg atgttggaat
      361 ttattactgc gggcaaggta cacagcttcc tcccacgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01006240             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:21245:16926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006240
VERSION     KCVT01006240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21245:16926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83765.1"
                     /translation="CQHSFRTPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          117 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcaccg tcacttgcag ggctagtgag
      181 agcgttagca ccaaattaca ttggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctttgctg cgtccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggaacagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aactttttac
      361 tgtcagcata gttttcgtac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006241             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9799:18447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006241
VERSION     KCVT01006241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9799:18447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..284
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83766.1"
                     /translation="CQKYISSPFTF"
     J_segment       285..322
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           74 a           98 c           83 g           70 t
ORIGIN      
        1 acatgggtat tgactcagtc tccagccacc ctgtctctgt ctccagggga aagagccacc
       61 ctctcctgca gggccagtca gagtgttggc agcagcttag cctggtacca gcagaaacct
      121 gggcaggccc ccaggctcct cctctatggt gcatccagca gggccactgg catcccagac
      181 aggttcagtg gcagtgggtc tgggacagag ttcactctca ccatcagcag cctggagcct
      241 gaagattttg cagtatatta ctgtcagaaa tatattagct ccccattcac tttcggcccc
      301 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01006242             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16568:21453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006242
VERSION     KCVT01006242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16568:21453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83767.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtggggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006243             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7938:14498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006243
VERSION     KCVT01006243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7938:14498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83768.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagag atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag tagcagcgtt gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcactgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006244             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24996:13893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006244
VERSION     KCVT01006244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24996:13893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83769.1"
                     /translation="CLQYKSFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          114 c           99 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgaaacatcc agtttggcaa gtggggtccc atcaaggttc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcaacctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataag agtttcccgt acagttttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01006245             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17077:3576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006245
VERSION     KCVT01006245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17077:3576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83770.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cggtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaactct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006246             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:6404:14955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006246
VERSION     KCVT01006246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:6404:14955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83771.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          100 a          114 c          110 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcgaggttc agcggcagtg gttctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcacacgag
//
LOCUS       KCVT01006247             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12269:10963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006247
VERSION     KCVT01006247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12269:10963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83772.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          125 c          111 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006248             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21189:18191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006248
VERSION     KCVT01006248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21189:18191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83773.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          117 g          111 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cattctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006249             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11545:3695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006249
VERSION     KCVT01006249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11545:3695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83774.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006250             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14868:14269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006250
VERSION     KCVT01006250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14868:14269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..380
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83775.1"
                     /translation="CYQHSRGWAF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          122 c          117 g           83 t
ORIGIN      
        1 acatgggggg ctgctaggtt agtacccaga aggaaccatg gaagccccag ctcagcttct
       61 ctgccttctg ctactctggc tcccaggtac caccggacaa attatattga cacagtctcc
      121 agccaccctg tctttggcac caggggaaag agccactctc tcctgcaggg ccagtgagaa
      181 tgttggcagc tacttagcct ggtaccagca gaaccctggg caggctccca ggctcctcgt
      241 ccacagtgcg tccagcaggg ccactgacat cccagacagg ttcagtggca gtgggtctcg
      301 gacagagttc accctcacca tcagcagtct ggagcctgaa gatgttggag tctattactg
      361 ctatcaacat agcagggggt gggcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006251             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23493:16880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006251
VERSION     KCVT01006251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23493:16880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83776.1"
                     /translation="CQQYNSGPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          118 c          101 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccagcc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtgcca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtggcc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006252             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20809:4850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006252
VERSION     KCVT01006252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20809:4850"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83777.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006253             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15767:7690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006253
VERSION     KCVT01006253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15767:7690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..381
                     /note="immunoglobulin light chain variable region"
     V_region        143..381
     V_segment       143..343
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <321..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83778.1"
                     /translation="CLQPLEFPWTF"
     J_segment       344..381
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>384
                     /gene="IGKC"
BASE COUNT           87 a          105 c          102 g           90 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggaaaca cctatttgga atggtaccta cagaagccag
      181 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      241 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      301 aggatgttgg ggtttattac tgcttgcaac ctctagagtt tccgtggacg ttcggccaag
      361 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006254             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19472:20460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006254
VERSION     KCVT01006254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19472:20460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83779.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g           97 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacggattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01006255             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7841:16604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006255
VERSION     KCVT01006255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7841:16604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..418
                     /note="immunoglobulin light chain variable region"
     V_region        95..418
     V_segment       95..378
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83780.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       388..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>425
                     /gene="IGKC"
BASE COUNT          100 a          116 c          110 g           99 t
ORIGIN      
        1 acatggggag acccagtctg gacgcagcat ggacatcagg gtcctcgctc agcttctcgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagttgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcaa gtcaggacat
      181 tggcaattat ttagcctggt atcagcagaa accagggaaa gcccctaacc tcctgatcta
      241 taaggcgtcc agtttacaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagttt attactgtca
      361 acagcgtaat agttacccgt acatgtgcag ttttggcccg gggaccaaag tggagatccg
      421 acgag
//
LOCUS       KCVT01006256             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:7740:11114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006256
VERSION     KCVT01006256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7740:11114"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83781.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttaactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006257             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4518:8732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006257
VERSION     KCVT01006257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4518:8732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..359
                     /note="immunoglobulin light chain variable region"
     V_region        82..359
     V_segment       82..321
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83782.1"
                     /translation="CQQYDSDPLTF"
     J_segment       322..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           91 a           96 c           98 g           77 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggagacag agtcaccatc acttgtcggg cgagtcaggg
      121 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagtcccga agcccttgat
      181 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      301 tcaacagtat gacagtgacc cgctcacttt cggtggaggg accaaggtag agatcaaacg
      361 ag
//
LOCUS       KCVT01006258             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13919:15266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006258
VERSION     KCVT01006258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13919:15266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83783.1"
                     /translation="CQRYSYSTWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          119 c          115 g           92 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttggt ttggtaccag cagaaacctg ggcaggcccc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg tagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagattttgc agtatattac
      361 tgtcagaggt atagttactc cacgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006259             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10107:10519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006259
VERSION     KCVT01006259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10107:10519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..437
                     /note="immunoglobulin light chain variable region"
     V_region        116..437
     V_segment       116..400
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83784.1"
                     /translation="CQQNSNWPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          104 a          127 c          120 g           89 t
ORIGIN      
        1 acatgggggt cagagctctg gggaggaact gctcagttag gacccagagg gaaccatgga
       61 agccccagca cagcttctct tcctcctgct gctctggctc ccagatacca ccggagaaat
      121 agtgatgacg cagtctccag ccaccctgtc tttgtctcca ggagaaagag ccaccctctc
      181 ctgcagggcc agtcagagtg tcagcagcag cttagcctgg taccaacaaa aacctgggca
      241 ggctcccagg ctcctcatct atggtgcatc cagcagggcc actggcatcc cagacaggtt
      301 cagtggcagt gggtctggga cagacttcac tctcaccatc accagcctgg agcctgaaga
      361 tgttgcagtt tattattgtc agcagaatag taactggcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006260             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18956:19687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006260
VERSION     KCVT01006260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18956:19687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83785.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          121 c          109 g          112 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtaatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagtc ggcctccttc tcctgcaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaacatcta tttgaattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcat attgaaaatc accagagtgg aggctgagga
      361 tgttggcgtt tattactgca tacaatctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006261             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17031:13241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006261
VERSION     KCVT01006261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17031:13241"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83786.1"
                     /translation="CQRYSYSTWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g           91 t
ORIGIN      
        1 acatggggga gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttgg tttggtacca gcagaaacct gggcaggccc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtatatta
      361 ctgtcagagg tatagttact ccacgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006262             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:23158:6787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006262
VERSION     KCVT01006262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23158:6787"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83787.1"
                     /translation="CQQYDNDPYNF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          108 a          112 c          109 g           92 t
ORIGIN      
        1 acatgggggg agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagccaggac
      181 attaggagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa ggccttgatc
      241 tattacacat ccgttttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 atagaattca ctctcaccat cagcagcctg cagcctgatg atcttgcaac ttattactgt
      361 caacagtatg acaatgaccc gtacaatttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01006263             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16699:7518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006263
VERSION     KCVT01006263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16699:7518"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83788.1"
                     /translation="CQQYNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattaccaat gatttagcct ggtatcagca gagaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagtat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006264             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18801:12305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006264
VERSION     KCVT01006264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18801:12305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83789.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g           98 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctctactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01006265             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16362:12062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006265
VERSION     KCVT01006265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16362:12062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..424
                     /note="immunoglobulin light chain variable region"
     V_region        85..424
     V_segment       85..386
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83790.1"
                     /translation="CMQALEFPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           96 a          112 c          119 g          100 t
ORIGIN      
        1 acatggggag gtcaccttct cacaatgagg ctccctgctc agctcctggg actgctaatg
       61 ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccagt ctccctgccc
      121 gtcaccctta gagagccggc ctccatctcc tgcaggtcta gtcagagcct cttggatagt
      181 gaggatggaa acacctattt ggaatggtac ctacagaggc caggccagtc tccacagctc
      241 ttaatttatg aggtttccta ccgggcctct ggagtcccag acaggttcag tggcagtggg
      301 tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat
      361 tactgcatgc aagctctaga gtttccgtgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01006266             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:24521:7540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006266
VERSION     KCVT01006266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24521:7540"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83791.1"
                     /translation="CQQYNSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          113 c          105 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagcagaa accaggaaaa gccccgaagg ccttgatcta
      241 ttacgcatcc attttagaaa gtgcggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gtctgacgat tttgcaactt attactgtca
      361 acagtataac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006267             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20582:4147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006267
VERSION     KCVT01006267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20582:4147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83792.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          118 c          108 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagtcag
      181 gatattaata cctggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcggtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006268             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:18329:7607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006268
VERSION     KCVT01006268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18329:7607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..433
                     /note="immunoglobulin light chain variable region"
     V_region        98..433
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83793.1"
                     /translation="CMQALEFPRTF"
     J_segment       402..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>440
                     /gene="IGKC"
BASE COUNT           94 a          124 c          116 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgtatc cagtggtgac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgcggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt ggctcagaca ctgatttcac actgaaaatc agcagagtgg aggctgaaga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct cggacgttcg gccaggggac
      421 caaggtggaa atcgaacgag
//
LOCUS       KCVT01006269             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11645:4520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006269
VERSION     KCVT01006269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11645:4520"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83794.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          117 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006270             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13921:11664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006270
VERSION     KCVT01006270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13921:11664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83795.1"
                     /translation="CQEYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          105 a          111 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc aactcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 ggagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01006271             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18217:16863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006271
VERSION     KCVT01006271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18217:16863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83796.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01006272             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19585:15760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006272
VERSION     KCVT01006272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19585:15760"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83797.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          112 c          102 g           97 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cgttaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006273             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21559:15242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006273
VERSION     KCVT01006273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21559:15242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83798.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggattgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006274             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5173:7738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006274
VERSION     KCVT01006274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5173:7738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83799.1"
                     /translation="CQHSHGSPITF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgtttac aactatttac attggtatca gcagaaacca gggaaagccc ctaaggtcct
      241 gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg gcagtggatc
      301 tgggactgat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006275             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17469:9053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006275
VERSION     KCVT01006275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17469:9053"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83800.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagta ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006276             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:20317:13476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006276
VERSION     KCVT01006276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20317:13476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83801.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aattaacaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006277             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6574:8413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006277
VERSION     KCVT01006277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6574:8413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83802.1"
                     /translation="CQQDFDWPPPF"
     J_segment       390..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          126 c          109 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaaactcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcaatg ccagtgggtc
      301 tggaacagag ttttctctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ttgtcagcag gattttgact ggcctccgcc gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006278             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25822:22367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006278
VERSION     KCVT01006278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25822:22367"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..367
                     /note="immunoglobulin light chain variable region"
     V_region        28..367
     V_segment       28..329
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <307..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83803.1"
                     /translation="CMQPLEFPWTF"
     J_segment       330..367
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           85 a           95 c          106 g           84 t
ORIGIN      
        1 acatgggggc tccctggatc cagtggggac attgtgatga cccagactcc actctccctg
       61 tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag cctcttggat
      121 agtgaggatg gaaacaccta cttggaatgg tacctacaga agccaggcca gtctccacag
      181 ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt cagtggcagt
      241 gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      301 tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac caaggtggaa
      361 gtcaaacgag
//
LOCUS       KCVT01006279             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:9002:12986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006279
VERSION     KCVT01006279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9002:12986"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83804.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          125 c          114 g           85 t
ORIGIN      
        1 acctggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgctg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc agaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006280             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12141:19867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006280
VERSION     KCVT01006280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12141:19867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..467
                     /note="immunoglobulin light chain variable region"
     V_region        128..467
     V_segment       128..429
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <407..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83805.1"
                     /translation="CMQPLEFPWTF"
     J_segment       430..467
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>470
                     /gene="IGKC"
BASE COUNT          108 a          128 c          123 g          111 t
ORIGIN      
        1 atggggatac aagctcagca ctaaccttgc cttgactgat cacgactcct caggtcacct
       61 tctcacaatg aggctccctg ctcagctcct gggactgcta atgctctggc tccctggatc
      121 cagtggggac attgtgatga cccagactcc actctccctg tccgtcaccc ttggagagcc
      181 ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg gaaacaccta
      241 tttggaatgg tacctacaga agccaggcca gtctccacag ctcttgattt atgaagtttc
      301 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac
      361 actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca tgcaacctct
      421 agagtttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006281             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:6542:6966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006281
VERSION     KCVT01006281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6542:6966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..387
                     /note="immunoglobulin light chain variable region"
     V_region        66..387
     V_segment       66..349
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83806.1"
                     /translation="CQQYNSLPYSF"
     J_segment       350..387
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>390
                     /gene="IGKC"
BASE COUNT           94 a           99 c          101 g           96 t
ORIGIN      
        1 acatggggag ggtccccgct cagctcctgg ggctcctgct gctctggctc ccaggtgcca
       61 gatgtgacat tgagatgacc cagtctccat cctccctgtc tgcttctgta ggagacagag
      121 tcaccatcac ttgccgggca agtcagggcg ttaacgttta tttaaattgg tatcagcaga
      181 aaccggggaa agcccctaag cccctgatct tttatgtaaa ccgtttggaa cgtggggtcc
      241 catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc agcagcctgc
      301 aacctgaaga ttttgcaagt tattattgtc aacagtataa tagtttaccg tacagttttg
      361 gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01006282             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18964:6931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006282
VERSION     KCVT01006282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18964:6931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83807.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          107 g           94 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gcgcgaacgt
      181 taacaactat ttacattggt atcagcggaa accagggaaa gtccctgagc tcctgatcta
      241 tgctgcgtcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006283             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16990:18738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006283
VERSION     KCVT01006283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16990:18738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83808.1"
                     /translation="CQQYSSYPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          105 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg atcccaggtg ccagatgtga catccagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggagaca aagtcaccat cacttgccga gccagtcagg
      181 gtattagcag cttgttagcc tggtatcagc agaaaccagg gaaagcccct aagtccctga
      241 tctataaggc atccagtttg caaagtgggg tcccttcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tagtagttac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006284             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18045:10748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006284
VERSION     KCVT01006284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18045:10748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83809.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006285             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:10394:19673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006285
VERSION     KCVT01006285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10394:19673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83810.1"
                     /translation="CLQYKSFPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          112 a          116 c           98 g           99 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtgggaga cactgtcacc atcacttgcc ggacaagtca
      181 aggtattacc aattatttac attggtttca acagaaacca gggaaagccc ctaaactcct
      241 gatctatgaa acatccagtt tgacaagtgg ggtcccatca aggttcagcg gcagcgcatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg taacttatta
      361 ctgtctacag tataaaagtt tcccgtacac ttttggccag gggaccaaac tggagatcaa
      421 acgag
//
LOCUS       KCVT01006286             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18855:7079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006286
VERSION     KCVT01006286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18855:7079"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83811.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006287             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13953:9074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006287
VERSION     KCVT01006287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13953:9074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83812.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgaaga tggaaatacc tatttggaat ggcaccggca gatgccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc actctgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006288             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9738:20656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006288
VERSION     KCVT01006288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9738:20656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83813.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggaaagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006289             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12404:15637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006289
VERSION     KCVT01006289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12404:15637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83814.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          116 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccatggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006290             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13603:5605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006290
VERSION     KCVT01006290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13603:5605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83815.1"
                     /translation="CMQGLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggtt ggagacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtgt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006291             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22962:18397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006291
VERSION     KCVT01006291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22962:18397"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83816.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcgacagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006292             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11821:17520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006292
VERSION     KCVT01006292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11821:17520"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83817.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactactc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006293             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7819:8672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006293
VERSION     KCVT01006293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7819:8672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..349
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83818.1"
                     /translation="CLQGYIDPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           93 a          107 c          107 g           97 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc ttctgctctg
       61 gctcccaggt gccagatgtg acttccagat gacccagtct ccatcttccc tgtctgcatc
      121 ggtcggagac agagtcacca tcacttgccg ggcaagtcag gacattagcg attttttaag
      181 ttggtatcag cagaaaccag gaaaacctcc taagcgcctg atttatgctg catccagttt
      241 gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc ggcttattac tgtctacagg gttatattga
      361 cccgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01006294             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18443:6613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006294
VERSION     KCVT01006294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18443:6613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83819.1"
                     /translation="CLQYKSFPYTF"
     J_segment       390..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          116 c           99 g           99 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtattaccaa ttatttacat tggtttcagc agaaaccagg gagagcccct aagctcctga
      241 tctatgaaac atccagtttg acaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagta taaaagtttc ccgtatacct ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01006295             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24030:3420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006295
VERSION     KCVT01006295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24030:3420"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..373
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83820.1"
                     /translation="CQQVYSSPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           98 a          114 c          106 g          104 t
ORIGIN      
        1 acatgggagt cagtctcagt caggacacag catggacatg agggtccctg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgat atccagatga cccagtctcc
      121 atctgccttg tctgcatctg tgggagacag agtcaccatc tcttgccggg caagtcagaa
      181 catttatagt tatttagcgt ggtatcaaca gaaaccaggg aaagccccta agctcctgat
      241 ctatgctgta tccagattgc aaagtggggt tccctctcgg ttcagcggca gtggaactgg
      301 gacagatttc actctcagca tcagcagcct acagcctgaa gattctgccg gttattactg
      361 tcaacaggtt tatagtagtc cattcacttt cggccccggg accaaactgg ctatcaaacg
      421 ag
//
LOCUS       KCVT01006296             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5073:11074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006296
VERSION     KCVT01006296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5073:11074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..410
                     /note="immunoglobulin light chain variable region"
     V_region        99..410
     V_segment       99..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83821.1"
                     /translation="CQQYNTLPLTF"
     J_segment       380..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>420
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cactcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct gagctcctga
      241 tctattatgc aaaccgtttg gaaactgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttactgtc
      361 aacagtataa tactttaccg ctcactttcg gcggagggac caaggtggag gtcagacgag
//
LOCUS       KCVT01006297             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:8545:9100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006297
VERSION     KCVT01006297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8545:9100"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83822.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          113 c          108 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa acctggaaaa cctcctcagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt attactgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006298             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:14710:17188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006298
VERSION     KCVT01006298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14710:17188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83823.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgctt gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatctggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006299             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4993:12457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006299
VERSION     KCVT01006299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4993:12457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83824.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca caagccaggc
      241 cagtctccag agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagatt ggaggctgag
      361 gatgttgggc tttattactg tatgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg aggtcaaacg ag
//
LOCUS       KCVT01006300             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14494:5059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006300
VERSION     KCVT01006300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14494:5059"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83825.1"
                     /translation="CSQDIQLPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           88 a          123 c          123 g          107 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctggggct gctggtgctc tggctccctg ggaccagtgg ggatattgtg atgactcaga
      121 ctccactctc cctgtccgtc acccctggag acccggcctc catctcctgt aggtctagtc
      181 agagcctcct acataggaat ggatacacct atttgttttg gtacctgcag aagccaggcc
      241 agtctccaca gctcctgatc tatttgggtt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagccgggtg gaggctgagg
      361 atgttggggt ttattactgc tcgcaagata tacagcttcc gctcactttc ggtggaggga
      421 ccagggtgga gatcaaacga g
//
LOCUS       KCVT01006301             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12719:17863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006301
VERSION     KCVT01006301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12719:17863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83826.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          110 c          101 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgattta
      241 ttatacaaat cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006302             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:19961:8306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006302
VERSION     KCVT01006302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19961:8306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83827.1"
                     /translation="CLQGDTAPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          113 c          113 g           96 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattaa cgattattta agttggtatc agcagaaacc aggaaaacct cctaagcgcc
      241 taatctatgc tgcatctagt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcagtttatt
      361 actgtctaca gggtgatact gccccgttca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006303             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10629:17009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006303
VERSION     KCVT01006303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10629:17009"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83828.1"
                     /translation="CQQYNNLPYTF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          112 c          103 g          100 t
ORIGIN      
        1 acatggggga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg cttctttagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 agcagttttt tgaattggta tcagcagaaa ccggggaaag cccctaacct cctgatctat
      241 tttgcaaacc gtttggagag tggggtccca tcaaggttca gcggcagtgg gtctgggaca
      301 agattcactc tcaccatcag cagcctccaa cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataata atttaccgta cacttttggc caggggacca aagttgagat caaacgag
//
LOCUS       KCVT01006304             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:7360:9626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006304
VERSION     KCVT01006304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:7360:9626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83829.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g          104 t
ORIGIN      
        1 acatgggggt tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006305             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12061:19228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006305
VERSION     KCVT01006305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12061:19228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83830.1"
                     /translation="CMQSLEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctggccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc tagagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa tctctagagt ttcctctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01006306             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13585:6560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006306
VERSION     KCVT01006306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13585:6560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83831.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac cttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006307             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14508:11613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006307
VERSION     KCVT01006307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14508:11613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83832.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccattaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006308             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14325:21932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006308
VERSION     KCVT01006308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14325:21932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83833.1"
                     /translation="CQQYNSLPYSF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          103 a          107 c          109 g           98 t
ORIGIN      
        1 atggggagac ccagtcagga cacagcatgg acatgagggt ccccgctcag ctcctggggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacattga gatgacccag tctccatcct
      121 ccctgtctgc ttctgtagga gacagagtca ccatcacttg ccgggcaagt cagggcgtta
      181 acgtttattt aaattggtat cagcagaaac cggggaaagc ccctaagccc ctgatctttt
      241 atgcaaaccg tttggaacgt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 aattcactct caccatcagc agcctgcaac ctgaagattt tgcaagttat tattgtcaac
      361 agtataatag tttaccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01006309             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20018:14248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006309
VERSION     KCVT01006309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20018:14248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83834.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccacccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggcg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006310             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:15015:14793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006310
VERSION     KCVT01006310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15015:14793"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83835.1"
                     /translation="CLQFKSYPNSF"
     J_segment       381..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT           97 a          116 c          108 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg ggtctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attgctgtct
      361 acagtttaaa agttacccga acagttttgg ccaggggacc aaagtggaga tcaagcgag
//
LOCUS       KCVT01006311             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13209:20714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006311
VERSION     KCVT01006311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13209:20714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..387
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <370..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83836.1"
                     /translation="CGQGTHWPTF"
     J_segment       393..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          119 c          120 g           92 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctaatgc tctgcgtccc cgagtccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 ctgcacagtg atggaaacac ctacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggctcctga tttataaggt ttctaaccgg gactctgggg tcccagacag attcagtggc
      301 agtgggacag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttatcact gcgggcaagg tacacactgg ccgacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01006312             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18609:15545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006312
VERSION     KCVT01006312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18609:15545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83837.1"
                     /translation="CQQGHSYPWTF"
     J_segment       383..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag tcgagtctag
      181 gcattggcaa atttttaaat tggtatcagc agaaaccagg gaaagccccc aaactcctga
      241 tctatagggc atccagtttg caaactggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc gcttattact
      361 gtcaacaggg tcatagttac ccgtggacgt tcggccaagg gaccaaggtg gagatgaaac
      421 gag
//
LOCUS       KCVT01006313             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7408:14071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006313
VERSION     KCVT01006313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7408:14071"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83838.1"
                     /translation="CLQYKSYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          105 a          113 c          102 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 tagcacttat ttaaattggt ttcagcagat accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc ctcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa agttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01006314             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17150:6582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006314
VERSION     KCVT01006314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17150:6582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83839.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tacatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006315             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17631:13556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006315
VERSION     KCVT01006315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17631:13556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83840.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          121 c          116 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcatc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006316             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20253:17728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006316
VERSION     KCVT01006316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20253:17728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83841.1"
                     /translation="CQKYISSPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          130 c          106 g           91 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaacttat attgactcag
      121 tctccagcca ccctgtctct gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc ccccaggctc
      241 ctcctctatg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt tgcagtatat
      361 tactgtcaga aatatattag ctccccattc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01006317             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5055:15550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006317
VERSION     KCVT01006317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5055:15550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83842.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc tgggagagcc ggcctccatc tcctgccggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg cacctgcaga ggccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggtatt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006318             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14173:16952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006318
VERSION     KCVT01006318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14173:16952"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83843.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcagctgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acagtataac agtgacccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006319             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8321:16896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006319
VERSION     KCVT01006319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8321:16896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83844.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgtgtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccgaggtgga aatcaaacga g
//
LOCUS       KCVT01006320             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15764:12923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006320
VERSION     KCVT01006320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15764:12923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83845.1"
                     /translation="CVQGYSAPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          107 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcttc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gaaaaactcc tcagcgcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa gattcagcgg cagtggctct
      301 gggacagaat tcactctcgc catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtgtacagg gttatagtgc cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006321             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19226:15946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006321
VERSION     KCVT01006321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19226:15946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83846.1"
                     /translation="CQQGDSYPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          112 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagtct
      121 ccttcctccc tgtctgcatc tgtgggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagag attatttaaa ttggtatcag cagcaaccgg ggaaagcccc taaactcctg
      241 atgtattatg caaacagtct ggcaagtgga gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcagtctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagg gtgacagtta tcctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006322             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6068:15683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006322
VERSION     KCVT01006322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6068:15683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..368
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83847.1"
                     /translation="CLQGYIPPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          116 c          108 g           99 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cttccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttttttaagt tggtatcagc agaaacctgg aaaacctcct aaccgcctga
      241 tttatgctgc atccagtttg caaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgcg acttattact
      361 gtctacaggg ctatattccc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006323             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9123:10670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006323
VERSION     KCVT01006323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9123:10670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83848.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          120 c          104 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgttggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gacattacga atgatttagc ctggtatcaa cagaaaccaa ataaagcccc gaagcccctg
      241 atctattacg cctccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006324             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21583:12439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006324
VERSION     KCVT01006324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21583:12439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..289
                     /note="immunoglobulin light chain variable region"
     V_region        15..289
     V_segment       15..251
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83849.1"
                     /translation="CQQYDSDPFTF"
     J_segment       254..289
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>292
                     /gene="IGKC"
BASE COUNT           75 a           71 c           80 g           66 t
ORIGIN      
        1 acatgggggg agtcagaccc agtctccatc acttgtcggg cgagtcaggg cattcgcagt
       61 tatttagcgt ggtatcagca gaaaccaggg aaagtcccga agcccttgat ctattacgcg
      121 tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc
      181 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagtat
      241 gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg ag
//
LOCUS       KCVT01006325             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18113:6422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006325
VERSION     KCVT01006325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18113:6422"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..321
                     /note="immunoglobulin light chain variable region"
     V_region        1..321
     V_segment       1..283
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83850.1"
                     /translation="CQQYNSDPFTF"
     J_segment       284..321
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>324
                     /gene="IGKC"
BASE COUNT           87 a           83 c           79 g           75 t
ORIGIN      
        1 acatggggat gacccagtct ccatcctccc tgtctgcatc tgtaggagac agagtaacca
       61 tcacttgtcg ggcgagtcag gacataagaa gttatttagc gtggtatcag cagaaagcag
      121 gcaaagcccc gaagcccttg atctattacg catccgtttt ggaaagtggg gtcccatcaa
      181 ggttcagtgg cagtggatct gggacagaat tcactctcac catcagcagt ctgcagcctg
      241 aggattttgc aacttattac tgtcaacagt ataacagtga cccattcact ttcggccccg
      301 ggaccaaact ggataccaaa cgag
//
LOCUS       KCVT01006326             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15258:8501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006326
VERSION     KCVT01006326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15258:8501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83851.1"
                     /translation="CQQYNSLPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           99 a          103 c          105 g           97 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattgagat gacccagtct ccatcctccc tgtctgcttc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag ggcgttaacg tttatttaaa
      181 ttggtatcag cagaaaccgg ggaaagcccc taagcccctg atcttttatg caaaccgttt
      241 ggaacgtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaacctg aagattttgc aagttattat tgtcaacagt ataatagttt
      361 accgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01006327             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17786:19990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006327
VERSION     KCVT01006327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17786:19990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83852.1"
                     /translation="CLQGDTAPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagaagtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atctatgctg catccagttt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcgctctcac catcagtggc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagg gtgatactgc cccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006328             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:13053:20789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006328
VERSION     KCVT01006328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13053:20789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..371
                     /note="immunoglobulin light chain variable region"
     V_region        50..371
     V_segment       50..324
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83853.1"
                     /translation="CQQHNNYSPTF"
     J_segment       337..371
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>374
                     /gene="IGKC"
BASE COUNT           99 a          103 c           90 g           82 t
ORIGIN      
        1 acatggggga gtcagaacca ctcagctctg gctcccaggt gccagatgtg acatccagat
       61 gacccagtct ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg
      121 ggcaagtcag ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc
      181 gaagcccctg atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg
      241 cagtggatct gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc
      301 aacttattac tgtcaacaac ataataatta ctctcccact ttcggcggag ggaccaaggt
      361 ggagatcaaa cgag
//
LOCUS       KCVT01006329             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6484:16365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006329
VERSION     KCVT01006329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6484:16365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83854.1"
                     /translation="CQQYDGDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          111 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc agtttggaaa gtggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac ggtgacccgt tcactttcgg tggagggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01006330             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5290:17282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006330
VERSION     KCVT01006330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5290:17282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83855.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaacgag
//
LOCUS       KCVT01006331             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14363:5789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006331
VERSION     KCVT01006331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14363:5789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83856.1"
                     /translation="CMQYRHIPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          119 c          115 g          110 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaagctcc ctgctcagct
       61 cctggggctg ctaatgctct ggctctctgg ttccagtggg gatgttgtga tgacccagac
      121 tccattctcc ctgtccgtta gccctggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg aatagtgaag acggaaacac ctatttggat tggtacctgc agaggccggg
      241 ccagtctcca cagcccttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa attaacagag tggaggctga
      361 ggatgttggg atttatatct gcatgcaata tagacacatt ccattcactt tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01006332             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8745:17273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006332
VERSION     KCVT01006332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8745:17273"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83857.1"
                     /translation="CMQALDFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          127 c          112 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttcg atagtgaaga aggaaacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttctcaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagactttc cattcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01006333             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10249:21903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006333
VERSION     KCVT01006333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10249:21903"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83858.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          122 g          107 t
ORIGIN      
        1 acctggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006334             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24441:7749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006334
VERSION     KCVT01006334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24441:7749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83859.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          100 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgga gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006335             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12297:5372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006335
VERSION     KCVT01006335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12297:5372"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83860.1"
                     /translation="CMQSLEIPPTF"
     J_segment       400..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt ggggatggaa acacctattt ggattggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aatctctaga gattcctccc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01006336             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20427:17772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006336
VERSION     KCVT01006336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20427:17772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..416
                     /note="immunoglobulin light chain variable region"
     V_region        77..416
     V_segment       77..378
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83861.1"
                     /translation="CMQALDFPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           91 a          109 c          119 g          100 t
ORIGIN      
        1 acatgggctt ctcacaatga ggctccctgc tcagctcctg ggactgctaa tgctctggct
       61 ccctggatct agtggggaca ttgtgatgac ccagactcca ctctccctgc ccgtcaccct
      121 tggagagccg gcctccatct cctgtaggtc tagtcagagc ctcttggata gtgaggatgg
      181 aaacacctat ttggaatggt acctgcagaa gccagggcag tctccacaac tcttgattta
      241 tgaggtttcc gaccgggcct ctggagtccc agacaggttc agtggcagtg ggtcagacac
      301 tgatttcaca ctgaaaatca gcagagtgga ggctgaggat gttggggttt attactgcat
      361 gcaagctctg gactttccgt ggacgttcgg ccaagggacc aaggtggaag tcaaacgag
//
LOCUS       KCVT01006337             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20241:6900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006337
VERSION     KCVT01006337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20241:6900"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83862.1"
                     /translation="CQQHESYPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          124 c          105 g           89 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 cgacattagc gattctttag cctggtatca gcacaaacca ggaaaagccc cgaagcccct
      241 gatctattac gcatccaatt tgaaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacctatta
      361 ctgtcaacag catgaatctt acccgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006338             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16662:10820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006338
VERSION     KCVT01006338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16662:10820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83863.1"
                     /translation="CQQHNEYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          119 c          107 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatgaat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006339             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19695:7833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006339
VERSION     KCVT01006339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19695:7833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83864.1"
                     /translation="CQQYDSFPLTF"
     J_segment       388..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          117 c          110 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtgggag acagagtcac catcacttgc cgggctagtc
      181 aggacattag taatttttta aattggtatc agcagaaacc ggggaaagcc cctaagctcc
      241 tgatctatta tggaaaccgt ttgggaagcg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaggatttt gcgacttatc
      361 attgtcagca gtatgatagt ttccccctca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01006340             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5639:10721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006340
VERSION     KCVT01006340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5639:10721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83865.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          124 c          113 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaacctgg gcaggctccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagactt cactctcacc atcaccagcc tggagcctga agatgttgca gtttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006341             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21889:10853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006341
VERSION     KCVT01006341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21889:10853"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83866.1"
                     /translation="CQQVYSNPAF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          101 a          111 c          107 g           98 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccaggtgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataggaa tttagcgtgg tatcagcaga aaccagggaa agcccctaag ctcctgatct
      241 ttgctgcatc cagattgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcaacctac agcctgaaga ttctgcaatt tattactgtc
      361 aacaggttta tagtaacccg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01006342             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19683:15418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006342
VERSION     KCVT01006342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19683:15418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83867.1"
                     /translation="CQQYDSDPRTF"
     J_segment       387..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          102 a          117 c          113 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaat
      421 cgag
//
LOCUS       KCVT01006343             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5408:6087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006343
VERSION     KCVT01006343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5408:6087"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83868.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagat actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006344             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18103:10522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006344
VERSION     KCVT01006344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18103:10522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..390
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83869.1"
                     /translation="CGQGTQLPPTF"
     J_segment       394..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           97 a          122 c          117 g           94 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcaccaga agccaggcca acctccaagg
      241 cgcctaattt atgaggtttc ttaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      361 tattactgcg ggcaaggtac acagcttcct cccacgttcg gccaagggac caaggtggac
      421 atcaaacgag
//
LOCUS       KCVT01006345             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19977:16004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006345
VERSION     KCVT01006345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19977:16004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83870.1"
                     /translation="CQQHDNSPPTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          117 c          113 g           93 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg gcacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccttcc tccctgtctg catctatagg cgacagagtc accatcactt gcagagccag
      181 tcagggtatt agcgactggt tggcctggta tcaacagaaa ccagggaaag cccctaaact
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag gctgaagatt tcgcaacata
      361 tttctgtcaa cagcatgata attcccctcc cactttcggt ggagggacta aggtggagat
      421 caaacgag
//
LOCUS       KCVT01006346             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15691:11974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006346
VERSION     KCVT01006346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15691:11974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83871.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          116 c          103 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac aacatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacta tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01006347             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16343:9178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006347
VERSION     KCVT01006347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16343:9178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83872.1"
                     /translation="CQQDYHWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          124 c          110 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gacatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca ccagaagcct gggcaggctc ccaagctcct
      241 catctatggt ccatccatca gggccagcgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagaa tttactctca ccatcagcag cctggagact gaagatattg gagtttattt
      361 ctgtcagcag gattatcact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006348             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8230:18728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006348
VERSION     KCVT01006348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8230:18728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83873.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac cgttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg acagtgggga tggaaacagc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006349             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7117:18174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006349
VERSION     KCVT01006349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7117:18174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83874.1"
                     /translation="CMQALEFPLPF"
     J_segment       406..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctccctttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006350             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22269:11186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006350
VERSION     KCVT01006350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22269:11186"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83875.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacctattac
      361 tgtcaacagt atgacagtga tccgttcact ttcggtgggg ggaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01006351             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7200:3646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006351
VERSION     KCVT01006351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7200:3646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83876.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgacg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcgga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006352             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6434:11548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006352
VERSION     KCVT01006352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6434:11548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83877.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006353             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16979:8334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006353
VERSION     KCVT01006353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16979:8334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83878.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006354             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9455:6593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006354
VERSION     KCVT01006354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9455:6593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83879.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagc caggttcatt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006355             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10141:3092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006355
VERSION     KCVT01006355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10141:3092"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..411
                     /note="immunoglobulin light chain variable region"
     V_region        94..411
     V_segment       94..372
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83880.1"
                     /translation="CQQGYSYHPTF"
     J_segment       381..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>418
                     /gene="IGKC"
BASE COUNT           93 a          119 c          107 g           99 t
ORIGIN      
        1 acatgggagt ctcagtcagg acacagcatg gacatgaggg tccccgctca gctccttggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacttcc ttatgacgca gtctccttcc
      121 tccctgtccg catctgtagg agacacagtc accatcactt gccaggcgag tcaagccatt
      181 ggcactaatt taaattggta tcagcagaga ccaggaaaag cccctaaact cctgatctat
      241 agggcttccg gtttgcagag tgggactccc tctcggttca gcggcagtgg atctgggacg
      301 gatttcagtc tcaccatcag cagcctgcag cctgaagatt ttgccactta ttactgtcaa
      361 cagggttata gttaccatcc cactttcggc ggagggacca aggtggagat ccaacgag
//
LOCUS       KCVT01006356             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24598:12410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006356
VERSION     KCVT01006356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24598:12410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83881.1"
                     /translation="CLQYKGYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          117 c          109 g          100 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gcccgatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcttc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 ggtcttagca gttctttaca ttggtttcaa cacaaaccag ggaaagcccc taggctcctg
      241 atctatgctg catccagttt ggcaggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaggtta cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006357             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19835:14129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006357
VERSION     KCVT01006357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19835:14129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83882.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca attatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ctcgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01006358             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15347:2386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006358
VERSION     KCVT01006358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15347:2386"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..379
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83883.1"
                     /translation="CQRYSYSTWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           97 a          119 c          115 g           91 t
ORIGIN      
        1 atggggagag ctgctcagtt aggacccaga gagaaccatg gaaatcccag ctcagcttct
       61 cttcctcctg ctactgtggc tcccaggtac caccggacaa gttatattga ctcagtctcc
      121 agccaccctg tctttgtctc caggggaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgttggcagc agcttggttt ggtaccagca gaaacctggg caggccccca ggctcctcat
      241 ctatggtgca tccagcaggg ccactggcat cccagacagg ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gattttgcag tatattactg
      361 tcagaggtat agttactcca cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006359             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10875:8142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006359
VERSION     KCVT01006359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10875:8142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83884.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctaatcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggcacctgca gaagccaggc
      241 cagtctctac aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatttctg catgcaggct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006360             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:4782:18479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006360
VERSION     KCVT01006360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4782:18479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83885.1"
                     /translation="CQRYIYSTWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          119 c          114 g           92 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcccct gctactgtgg ctcccaggta ccaccggaca agttatattg actcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcag cagtttggtt tggtaccagc agaaacctgg gcaggccccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agattttgca gtatattact
      361 gtcagaggta tatttactcc acgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006361             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20851:7801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006361
VERSION     KCVT01006361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20851:7801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..430
                     /note="immunoglobulin light chain variable region"
     V_region        96..430
     V_segment       96..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83886.1"
                     /translation="CMQALEFPLTF"
     J_segment       394..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           92 a          121 c          120 g          100 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cgagtccagt gggggtgttg ttatgactca gtttccgctc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtgcacacca atggatacac atacttgagt tggtatcacc agaggccagg ccaacctcca
      241 aggcgcctca tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttatcact gcatgcaagc tctagagttt cctctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01006362             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14001:21263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006362
VERSION     KCVT01006362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14001:21263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83887.1"
                     /translation="CQQHDNAPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          116 c          113 g           85 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctataggac atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcagcagca tgacaatgcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006363             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23494:20057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006363
VERSION     KCVT01006363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23494:20057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83888.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tataggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgg aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006364             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14585:11464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006364
VERSION     KCVT01006364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14585:11464"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83889.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggtc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006365             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22107:8613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006365
VERSION     KCVT01006365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22107:8613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83890.1"
                     /translation="CMQALQFPWTF"
     J_segment       240..277
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           69 a           60 c           82 g           69 t
ORIGIN      
        1 acatgggggt ctagtcagag cctcttggat agtgaggatg gaaacaccta tttggaatgg
       61 tacctacaga ggccaggcca gtctccacac ctcttgattt atgagttttc caatcgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac tctgaatatc
      181 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct acaatttccg
      241 tggacgttcg gccaagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006366             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:5161:20739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006366
VERSION     KCVT01006366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5161:20739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83891.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga aaccaggcca
      241 gtctccacga ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006367             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15096:8563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006367
VERSION     KCVT01006367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15096:8563"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83892.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaagt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tctggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006368             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7205:11535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006368
VERSION     KCVT01006368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7205:11535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83893.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          125 c          111 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga gacagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006369             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:24224:6663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006369
VERSION     KCVT01006369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24224:6663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83894.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgagt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006370             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18070:19839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006370
VERSION     KCVT01006370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18070:19839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83895.1"
                     /translation="CQQDFDWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          128 c          118 g           90 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc
      241 tcccaagctc ctcctctatg gtgcatccac cagggcctcc ggcatcccag gcaggttcag
      301 tgccagtggg tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt
      361 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006371             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20450:4541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006371
VERSION     KCVT01006371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20450:4541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83896.1"
                     /translation="CQQHDNSPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          116 c          111 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgataattcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006372             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24446:6813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006372
VERSION     KCVT01006372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24446:6813"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83897.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006373             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8933:16364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006373
VERSION     KCVT01006373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8933:16364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..306
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83898.1"
                     /translation="CLQYNSSPLTF"
     J_segment       307..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           87 a           96 c           86 g           78 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct ccctgtctgc
       61 atctgtagga gacacagtca ccatcacttg ccgggcgagt cagactatta gcagctggtt
      121 agactggtat cagcagaaac cagggaaagc ccctaacctc ctgatcttta aggcatccag
      181 tttgcaaagt ggggtcccct caaggttcag cggcagtgga tctgggacag aattcactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tattgtctac agtacaatag
      301 tagcccgctc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006374             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17571:19004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006374
VERSION     KCVT01006374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17571:19004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83899.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          120 c          108 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgggggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006375             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8137:9513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006375
VERSION     KCVT01006375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8137:9513"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83900.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          112 a          118 c          109 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagcc
      181 acgatataaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaagctcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc agcatcagca gcctgcagcc tgaagatttc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006376             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7914:7437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006376
VERSION     KCVT01006376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7914:7437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83901.1"
                     /translation="YMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactac atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006377             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8864:20669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006377
VERSION     KCVT01006377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8864:20669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..382
                     /note="immunoglobulin light chain variable region"
     V_region        126..382
     V_segment       126..351
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <329..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83902.1"
                     /translation="CQQYNTLPLTF"
     J_segment       352..382
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>392
                     /gene="IGKC"
BASE COUNT           96 a          107 c          102 g           87 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac actcagatga cccagtctcc
      121 atcctccatc acttgccggg caagtcagga cattaacatt tatttaaatt ggtatcagca
      181 gaaaccgggg aaagcccctg agctcctgat ctattatgca aaccgtttgg aaactggggt
      241 cccatcaagg ttcagcggcg gtggatctgg gacagaattc agtctcacca tcagcagcct
      301 gcaacctgag gactttgcaa cttattactg tcaacagtat aatactttac cgctcacttt
      361 cggcggaggg accaaggtgg aggtcagacg ag
//
LOCUS       KCVT01006378             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9259:19413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006378
VERSION     KCVT01006378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9259:19413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83903.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          112 c          101 g           98 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgttac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cgttaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006379             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23499:17066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006379
VERSION     KCVT01006379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23499:17066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83904.1"
                     /translation="CLQGYNIPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          110 c          113 g           98 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccagt tgacccagtc
      121 tccatcttcc ctgtctgcat cggtagggga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gtgtccagtt tggaaggtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtctacag ggttataata tcccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006380             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15484:7259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006380
VERSION     KCVT01006380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15484:7259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..351
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83905.1"
                     /translation="CQQYDSDSLTF"
     J_segment       356..393
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           95 a          108 c          101 g           92 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc tcctagtact cctgctgctc tgtctcccag
       61 gtgccaaatg tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag
      121 acagagtcac catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc
      181 agcagaaacc agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg
      241 gggtcccatc aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca
      301 gcctgcagcc tgaagatttt gcaacttatt actgtcaaca gtatgacagt gattcgctca
      361 ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01006381             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19483:16364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006381
VERSION     KCVT01006381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19483:16364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83906.1"
                     /translation="CMQYTHMPLTF"
     J_segment       401..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggat ccagtgggga tgttgtgttg acccagactc
      121 cactctccct gtccgtcacc cccggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaagat ggaaacacct atttggattg gtacctacaa aagccgggcc
      241 agtcgccaca gcccttgatt tatgaggttt ccaatcgggc ctctggagtc cctgacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaatata cacacatgcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcgaacga g
//
LOCUS       KCVT01006382             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:5474:14436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006382
VERSION     KCVT01006382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:5474:14436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83907.1"
                     /translation="CQQSYRYPLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgatccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaac aactatttac actggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatgtatctt gcatccactt tgcagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctcg ccatcagcag cctgcagcct gaagatgctg caacttatta
      361 ctgtcagcag agttatcgtt atccgctcac tttcggtgga gggacccagg tggaaatcaa
      421 tcgag
//
LOCUS       KCVT01006383             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17792:11626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006383
VERSION     KCVT01006383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17792:11626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83908.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccattgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006384             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21957:8702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006384
VERSION     KCVT01006384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21957:8702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..400
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83909.1"
                     /translation="CLQDIQFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           91 a          123 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctggggct gctggtgctc tggctccctg ggaccagtgg ggatattgtg ttgactcaga
      121 ctccagtctc cctgtccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct tcaaactaat ggaaacacct atttgttttg gtacctgcag aagccaggcc
      241 agtctccaca actcctgatc tacttgggtt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagccgggtg gaggctgaag
      361 atgttggggt ttattactgc ttgcaagata tacagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006385             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19108:13410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006385
VERSION     KCVT01006385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19108:13410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83910.1"
                     /translation="CMQALEFPRTF"
     J_segment       406..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          124 c          122 g           98 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctggccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggctagagag gatggaaaca cctatttgga ctggtacctg cagaggccag
      241 gccagactcc ccagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 gggtcagagg cagtgggtca gacactgagt tcacactgaa aatcagcaga gtggaggctg
      361 aagatcttgg gatttattac tgcatgcaag ctctagagtt tcctcggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006386             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19196:15239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006386
VERSION     KCVT01006386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19196:15239"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83911.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          126 c          120 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaacagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01006387             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24682:6489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006387
VERSION     KCVT01006387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24682:6489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83912.1"
                     /translation="CMQPLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat acagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgtcggggt ttattactgc atgcaacctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006388             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11872:10733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006388
VERSION     KCVT01006388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11872:10733"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83913.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgcc aatgctctgg ctccctggat tcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccgt ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct ttttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtgt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaagtgga aatcaaacga g
//
LOCUS       KCVT01006389             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16611:15056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006389
VERSION     KCVT01006389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16611:15056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83914.1"
                     /translation="CLQYKSFPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          107 c          106 g          105 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccatcac ttgccgggca agtcaggata
      181 ttaacagtta tttaaattgg tttcagctga aaccagggaa agccccaaag gtcctgatct
      241 atgctgcatc cagtttggaa agtggggtcc cgtctaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agtagcctgc agcctgaaga ttttgcaact tattattgtc
      361 tacagtataa aagttttcct ctcactttcg gtggagggac caaggtggat atcaaacgag
//
LOCUS       KCVT01006390             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19168:14463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006390
VERSION     KCVT01006390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19168:14463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83915.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006391             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16077:11101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006391
VERSION     KCVT01006391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16077:11101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83916.1"
                     /translation="CMQGLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          117 c          126 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccgctctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgaggt tggagacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtg tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006392             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16880:5140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006392
VERSION     KCVT01006392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16880:5140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83917.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          113 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006393             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20977:4766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006393
VERSION     KCVT01006393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20977:4766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83918.1"
                     /translation="CQQGDSYPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          107 a          113 c          115 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgtccca
      121 gtctccttcc tccctgtctg catctgtggg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt agagattatt taaattggta tcagcagcaa ccggggaaag cccctaaact
      241 cctgatgtat tatgcaaaca gtctggcaag tggagtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcagtc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagggtgaca gttatcctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01006394             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12629:7711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006394
VERSION     KCVT01006394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12629:7711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..445
                     /note="immunoglobulin light chain variable region"
     V_region        124..445
     V_segment       124..407
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83919.1"
                     /translation="CQQGSPFPWTF"
     J_segment       408..445
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>448
                     /gene="IGKC"
BASE COUNT          113 a          117 c          115 g          103 t
ORIGIN      
        1 acatgggaga ggctctttct ctgggatgtg gcatgagcaa aactgacaag tcaaggcagg
       61 aagatgttgt ctccatcaca actcattggg tttctgctgc tctgggttcc agcctccaag
      121 ggtgaaattg tgctgactca gtctccagcc tttcggtctg tgactctaaa ggagaaagtc
      181 accatcacct gccaggccag tcagagcatt ggtaatagct tacactggta ccagcagaaa
      241 ccggatcagt ctccaaagct cctcatcaaa tatgcttccc agtccatctc aggggtcccc
      301 tcaaggttca gtggcagtgg atctgggaca gatttcaccc tcaccatcaa cagcctggaa
      361 gctgaagatg ctgcgacgta ttactgtcag cagggaagtc ctttcccgtg gacgttcggc
      421 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01006395             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:4579:8531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006395
VERSION     KCVT01006395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4579:8531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83920.1"
                     /translation="CQQGDSYPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          112 c          112 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 ttcctccctg tctgcatctg tgggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagagat tatttaaatt ggtatcagca gcaaccgggg aaagccccta aactcctgat
      241 gtattatgca aacagtctgg caagtggagt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagggt gacagttatc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006396             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19584:15971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006396
VERSION     KCVT01006396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19584:15971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83921.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc cactggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01006397             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22137:14866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006397
VERSION     KCVT01006397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22137:14866"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..369
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83922.1"
                     /translation="CQQGRSYPLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          119 c          105 g           94 t
ORIGIN      
        1 acatgggggc agtctcagtc aggacacagc atggacatga gggtccccgc tcagctcctt
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac gcagtctcca
      121 tcctccctgt ccgcatctgt tggagacaca gtcaccatca cttgccaggc gagtcgagcc
      181 attgacaata atttacattg gtatcaacag aaaccaggga aagcccctaa actcctgatc
      241 gatagggcat ccaatttgca aagtgggatt ccctctcggt tcagcggcag tggatctggg
      301 acggatttca ctctcaccat caacagcctg cagcctgaag attttgccaa ttattactgt
      361 caacagggtc gtagttaccc gctcactttc ggcggaggga ccaaaatgga gatcaaacga
      421 g
//
LOCUS       KCVT01006398             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:26578:9055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006398
VERSION     KCVT01006398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26578:9055"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83923.1"
                     /translation="CQQSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          118 c          106 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtccg
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc tgagctcctg
      241 atctatgctg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggggcagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttatttc
      361 tgtcagcaaa gttatgatac cccctacact tttggccagg ggaccaaagt ggagattaaa
      421 cgag
//
LOCUS       KCVT01006399             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19347:16247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006399
VERSION     KCVT01006399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19347:16247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83924.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          114 c          104 g          100 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggtttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacttgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006400             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:19185:2864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006400
VERSION     KCVT01006400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19185:2864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83925.1"
                     /translation="FIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactacttc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006401             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21440:6481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006401
VERSION     KCVT01006401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21440:6481"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83926.1"
                     /translation="CHQHNSFPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          117 c          112 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctcagctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag aaacagtcac cgtcacttgt cgggcaagtc
      181 ggggcgttag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaggcccc
      241 tgatctacta tgcatccaat ttggagagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc acaatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcacca acataatagt ttcccgtaca gttttggcca ggggcccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006402             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4600:16627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006402
VERSION     KCVT01006402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4600:16627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83927.1"
                     /translation="CQQHDNMPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          114 c          115 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac agagtcacca tcacttgcag ggccagtcag
      181 ggtattagca actggttggc ctggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctataggg catggaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatcc
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgataatat gccgctcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01006403             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20378:4419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006403
VERSION     KCVT01006403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20378:4419"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83928.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac tctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006404             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:26827:10225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006404
VERSION     KCVT01006404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:26827:10225"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83929.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          123 c          116 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgt agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcttccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccagg gtggagatca
      421 aacgag
//
LOCUS       KCVT01006405             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23468:12271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006405
VERSION     KCVT01006405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23468:12271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83930.1"
                     /translation="CMQAVEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcaat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat gggaacacct atttgacatg gtacctgaag aagcctggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctg tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006406             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17653:6119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006406
VERSION     KCVT01006406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17653:6119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..387
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83931.1"
                     /translation="CMQALEFPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           90 a          113 c          121 g          103 t
ORIGIN      
        1 acatggtcag gtcaccttct cacaatgagg ctccctgctc agctcctggg actgctaatg
       61 ctctggctcc ctggatccag cggggacgta gtgatgaccc agactccact ctccctgtcc
      121 gtcacccttg gagagtcggc ctccatctcc tgcaggtcta gtcagagcct cttggatggt
      181 gaggatggaa acacctactt ggaatggtat ttgcagaagc caggccagtc tccacagctc
      241 ttgatttatg aggtttccaa gcgggcctct ggagtcccag acaggttcag tgtcagtggg
      301 tcaggcactg atttcacact gaaaatcagc agagtggagg ctggggatgt tggggtttat
      361 cactgcatgc aagctctaga gtttcctctc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006407             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14044:14601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006407
VERSION     KCVT01006407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14044:14601"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83932.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagatc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006408             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10904:13703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006408
VERSION     KCVT01006408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10904:13703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83933.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaagat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006409             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8416:17606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006409
VERSION     KCVT01006409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8416:17606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83934.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          122 c          115 g           87 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga caaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtatca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaatt ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006410             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:24115:14499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006410
VERSION     KCVT01006410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24115:14499"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83935.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          119 c          115 g           90 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagat ttcactctca ccatcagtag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006411             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11802:16416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006411
VERSION     KCVT01006411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11802:16416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83936.1"
                     /translation="CLQGYTIPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          114 c          107 g           95 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccgga caagtcaggg
      181 cattagcgat tatttaagtt ggtatcagca gaaaccagga aaagctccta agcgcctgat
      241 ccatgctgta tccagtttgg aaagtggggc cccatcaagg ttcagcggca gtggatctga
      301 aacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tctacagggt tatactatcc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006412             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19636:12976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006412
VERSION     KCVT01006412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19636:12976"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..276
                     /note="immunoglobulin light chain variable region"
     V_region        8..276
     V_segment       8..229
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83937.1"
                     /translation="CQQHNNYSPTF"
     J_segment       242..276
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           76 a           71 c           69 g           63 t
ORIGIN      
        1 acatgggagt caccatcact tgtcgggcaa gtcagggcat tagcaatgat ttagcctggt
       61 atcagctgaa accagggaaa gccccgaagc ccctgatcta ttacgcatcc aatttggaaa
      121 gtggggtccc atcaaggttc agcggcagtg gatctgggac agatttcact ctcaccatca
      181 gcagcctgca gcctgaagat tttgcaactt attactgtca acagcataat aattactctc
      241 ccactttcgg cggagggacc acggtggaga tcaaacgag
//
LOCUS       KCVT01006413             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:24252:10747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006413
VERSION     KCVT01006413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24252:10747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..425
                     /note="immunoglobulin light chain variable region"
     V_region        92..425
     V_segment       92..387
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83938.1"
                     /translation="CLQSKNSPWSF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           98 a          115 c          116 g           99 t
ORIGIN      
        1 acatggggag cctctagttc agctctcaga aatggggtcc tgggctcctt tcctgtggat
       61 cctcctgctc tgtgctccag gctgcagtgg ggacattgtg ctgacccagt ctccagcctc
      121 tttggccgtg tctccagggc agagggccac catcacctgc agagccagtg ggagtgtcag
      181 tgcctttgga ataagcctca ttcactggta tcaacagaaa ccaggacaac ctcctaaact
      241 cctgatttac caagcaatca ataaggagac tggggtccca gccaggttca gcggcagtgg
      301 gtctgggacc gatttcaccc tcacaattaa tcctgtggaa cctgacgatg gtgcagatta
      361 ttactgtctg cagagtaaga attctccgtg gtcgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01006414             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17726:2806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006414
VERSION     KCVT01006414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17726:2806"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83939.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          114 c          113 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagtcc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006415             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20123:4688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006415
VERSION     KCVT01006415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20123:4688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83940.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gctcgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006416             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:16573:19140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006416
VERSION     KCVT01006416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16573:19140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGKV3-9"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83941.1"
                     /translation="CQQGNSMPWTF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          109 a          113 c          109 g           98 t
ORIGIN      
        1 acatggggac gtttagcctg tgacagggct caggcaacat aatggatttt caggctcaaa
       61 ttttcatctt ccttctgctc agtgtcacag tgtccaatgg agaaattgtg ctgacccagt
      121 ctcccacatc catggctgtc tcccaaggag aaagagtcac catctcctgc acggccagct
      181 caagtgtaag taccagctac ttgcactggt accaacagaa gccaggattc cctccaaggc
      241 ttcttgtcta taggacatca agtctggctt ctggggtccc agccaggttc agtggcagcg
      301 gttctgggac ctcttacacg ctcacaatca gcaacatgga ggctgaagat gctgcaaact
      361 attactgtca gcaggggaat agcatgccgt ggacgttcgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01006417             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12412:7564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006417
VERSION     KCVT01006417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12412:7564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83942.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga aaccaggcca
      241 gtctccacga ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006418             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22425:20170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006418
VERSION     KCVT01006418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22425:20170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83943.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          118 c          107 g           85 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccgtc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaga caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcagcatca gcagcctgca gcctgaagat ttcgcaacac attactgtca
      361 acaacatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006419             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22676:18720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006419
VERSION     KCVT01006419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22676:18720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83944.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cgacctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006420             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8263:20011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006420
VERSION     KCVT01006420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8263:20011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83945.1"
                     /translation="CMQALDFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          122 c          121 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tgcagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgcg
      361 gatgttgggg tttattactg catgcaagct ctagactttc ccctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006421             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10408:10550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006421
VERSION     KCVT01006421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10408:10550"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83946.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          105 t
ORIGIN      
        1 acagggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccatgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactaatttc acactgagaa tcagtagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006422             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17212:8445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006422
VERSION     KCVT01006422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17212:8445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83947.1"
                     /translation="CQQYDTLPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          112 c          107 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttgacaatta tttaaattgg tatcaggaga aaccggggaa agcccctaag cccctgatct
      241 attatacaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt agatctggga
      301 cagaattcac tctcaccatc agcagccttc aacctgagga ttttgcaact tattactgtc
      361 aacagtatga tactttaccg tggacgttcg gccaagggac caaggtggac atcaaacgag
//
LOCUS       KCVT01006423             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14761:9705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006423
VERSION     KCVT01006423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14761:9705"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83948.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006424             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19759:7614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006424
VERSION     KCVT01006424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19759:7614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83949.1"
                     /translation="CLQGYNIPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          110 c          111 g           97 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagtt gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gaaaagctcc taagcgcctg
      241 atctatgctg tgtccagttt ggaaggtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc gacttattac
      361 tgtctacagg gatataatat cccgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006425             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21694:7564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006425
VERSION     KCVT01006425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21694:7564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83950.1"
                     /translation="CMQALEFPLSF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagactc
      121 cggtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgactttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcagtttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006426             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:12266:22003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006426
VERSION     KCVT01006426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12266:22003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83951.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          122 c          121 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgtcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01006427             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:6470:4468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006427
VERSION     KCVT01006427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:6470:4468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83952.1"
                     /translation="CQQYDSDLFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          114 c          112 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatttg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccgg agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc tgttcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006428             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9180:9772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006428
VERSION     KCVT01006428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9180:9772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83953.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          125 c          111 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacatctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006429             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12537:8682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006429
VERSION     KCVT01006429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12537:8682"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..384
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83954.1"
                     /translation="CQQHNSYPRTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          106 a          117 c          109 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcaactc
       61 ctggggctcc tgctgctctg gctcccaggt accagatgtg acatccagat gacccagtct
      121 ccatcttcct tgtctgcatc tgtaggagac agagtcacca tcacttgcca agccagtcag
      181 ggtattggca actggttagc ctggtatcgg cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg catccagttt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcagcagc ataatagtta tcctcggacg ttcggccaag ggaccaaggt ggaaatcaag
      421 cgag
//
LOCUS       KCVT01006430             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:6092:6010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006430
VERSION     KCVT01006430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6092:6010"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83955.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagactc tagaatttcc tctcaccttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006431             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13479:12473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006431
VERSION     KCVT01006431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13479:12473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83956.1"
                     /translation="CQQYNEYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          118 c          106 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaactagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagta taatgaatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006432             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21621:18941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006432
VERSION     KCVT01006432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21621:18941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83957.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          107 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagtgt caccatcgct tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gtccctgagc tcctgatcta
      241 tgctgcatcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gataccccct acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006433             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6712:5426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006433
VERSION     KCVT01006433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6712:5426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83958.1"
                     /translation="CMQARDFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          125 c          120 g          103 t
ORIGIN      
        1 actgggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cattggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttcgat agtgaggaag gaaacaccta tttggagtgg tacctgcaga ggccaggcca
      241 gtctccacag gtcttgattt atggggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgagaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agactttcca ttcactttcg gccccgggac
      421 caaactggac atcaaacgag
//
LOCUS       KCVT01006434             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12501:8038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006434
VERSION     KCVT01006434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12501:8038"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83959.1"
                     /translation="CQQYSSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          108 c          108 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt cacaatcact tgccgggcaa gtcagggcat
      181 tagcaattat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatgta
      241 ttatacaaac cgcttggaaa gtgggatccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgga acctgatgat tttgcaactt attactgtca
      361 acagtatagt tctttaccgt ggacgttcgg ccaagggacc aaggtggaat tcaaacgag
//
LOCUS       KCVT01006435             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:27325:15485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006435
VERSION     KCVT01006435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:27325:15485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83960.1"
                     /translation="CLQYKTYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          110 c          106 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tgctggttat ttaaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa acttatccgt acagttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006436             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16627:13431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006436
VERSION     KCVT01006436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16627:13431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83961.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatta
      421 aacgag
//
LOCUS       KCVT01006437             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10551:4519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006437
VERSION     KCVT01006437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10551:4519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83962.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag gtcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006438             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16244:11898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006438
VERSION     KCVT01006438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16244:11898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83963.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006439             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23455:18943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006439
VERSION     KCVT01006439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23455:18943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..300
                     /note="immunoglobulin light chain variable region"
     V_region        8..300
     V_segment       8..263
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83964.1"
                     /translation="CQQNSNWPLTF"
     J_segment       264..300
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>303
                     /gene="IGKC"
BASE COUNT           73 a           86 c           82 g           62 t
ORIGIN      
        1 acatgggagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
       61 agggccagtc agagtgtcag cagcagcaac aaaaacctgg gcaggctccc aggctcctca
      121 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      181 ggacagactt cactctcacc atcaccagcc tggagcctga agatgttgca gtttattatt
      241 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      301 gag
//
LOCUS       KCVT01006440             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17942:19396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006440
VERSION     KCVT01006440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17942:19396"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83965.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          127 c          112 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggacatca
      421 aacgag
//
LOCUS       KCVT01006441             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16176:13548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006441
VERSION     KCVT01006441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16176:13548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83966.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcggt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006442             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8604:16444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006442
VERSION     KCVT01006442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8604:16444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83967.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          118 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006443             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17010:13949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006443
VERSION     KCVT01006443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17010:13949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83968.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          108 c          108 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcaacagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006444             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18806:12263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006444
VERSION     KCVT01006444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18806:12263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83969.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          122 c          117 g          106 t
ORIGIN      
        1 acatgggctg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agcccttgat ttatgaggtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006445             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8158:19115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006445
VERSION     KCVT01006445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8158:19115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83970.1"
                     /translation="CMQALEFPLTF"
     J_segment       313..349
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           79 a           86 c          101 g           86 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcca tctcctgcag gtctagtcag agtctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacttgca gaaggcaggc cagtctccac agctcttgat ttatgaggtt
      181 tcctaccggg cctctggagt cccagacagg ttcagtggca gtgggtcagc cactgatttc
      241 aaactgaaca tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagtttc ctctcacttt cggtggaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006446             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15371:11449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006446
VERSION     KCVT01006446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15371:11449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83971.1"
                     /translation="CQQHDNFPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          112 a          115 c          101 g           95 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaac
      181 atattagcga ctggttggcc tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatcggac ttccaatttg gaaacaggag tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagtagct ttcagcctga agatatcgca acatattact
      361 gtcaacagca tgataatttc ccgtacattt ttgaccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01006447             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19219:5361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006447
VERSION     KCVT01006447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19219:5361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83972.1"
                     /translation="CQQHDNSPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagtctcag acagggcaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 cttcctccct gtctgcatct ataggcgaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattagcga ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcaggctga agatttcgca acatatttct
      361 gtcaacagca tgataattcc cctcccactt tcggtggagg gactaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006448             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23005:9775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006448
VERSION     KCVT01006448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23005:9775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..317
                     /note="immunoglobulin light chain variable region"
     V_region        113..317
     V_segment       113..279
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <257..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83973.1"
                     /translation="CMQALEFPWTF"
     J_segment       280..317
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>320
                     /gene="IGKC"
BASE COUNT           72 a           82 c           91 g           75 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccaggcca
      121 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      181 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      241 tcttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      301 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006449             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20404:6841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006449
VERSION     KCVT01006449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20404:6841"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83974.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          102 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacac atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01006450             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18000:7363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006450
VERSION     KCVT01006450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18000:7363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83975.1"
                     /translation="CQQYNALPLTF"
     J_segment       389..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>426
                     /gene="IGKC"
BASE COUNT          107 a          109 c          113 g           97 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattag tagttattta aattggtatc agcagaaacc ggggaaagcc cctaaggtcc
      241 tcatctatta tacaaaccgt ttggaaagtg gggtcccatc aaggttcagt ggcggtggat
      301 ctgggacaga gttcactctc accatcagca gcctgcaacc tgaggatttt gcaacttatt
      361 actgtcaaca gtataatgct ttaccgttga cgttcggcca agggaccaag gtggaaatca
      421 aaggag
//
LOCUS       KCVT01006451             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:6508:20431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006451
VERSION     KCVT01006451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6508:20431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83976.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc caagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006452             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21080:3680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006452
VERSION     KCVT01006452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21080:3680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83977.1"
                     /translation="CMQALEFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          116 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcctggg
       61 actgctcatg ctctggctcc ctgtatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatgtcc tgcaggtcta gtcagagtct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcggtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgatgatgt
      361 tggggtttat tactgcatgc aagctctaga gtttccgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006453             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22258:3185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006453
VERSION     KCVT01006453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22258:3185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83978.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga ccaaacgag
//
LOCUS       KCVT01006454             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:24723:14442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006454
VERSION     KCVT01006454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:24723:14442"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83979.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagacc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006455             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18872:18965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006455
VERSION     KCVT01006455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18872:18965"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83980.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          124 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt cccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006456             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19035:17631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006456
VERSION     KCVT01006456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19035:17631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83981.1"
                     /translation="CLQYNNLPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          114 c          103 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgc aaatcgtttg gaaactgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacccga agattttgca acttattact
      361 gtctccagta taataattta ccactcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006457             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16957:11568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006457
VERSION     KCVT01006457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16957:11568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83982.1"
                     /translation="CLQYKSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          112 c          100 g          102 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat cacttgccgg acaagtcagg
      181 atattcacat ttatttgaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tctctgctgc atccagtttg gaaagtgggt tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca acttattatt
      361 gtctacagta taaaagttac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006458             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:9745:9949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006458
VERSION     KCVT01006458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9745:9949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83983.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgagaa ttagcagagt ggaggctgag
      361 gatgttgggg ttttttactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006459             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25434:9011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006459
VERSION     KCVT01006459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25434:9011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83984.1"
                     /translation="CIQSLEFPWTF"
     J_segment       406..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          111 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccactg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccttctcctg taggtctagt
      181 cacagcctct tggatagtga ggatggatat atccatttgg attggtatct gcagaagcca
      241 ggccagtctc cacacctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggtttagtg gcagtgggtc agacactgat ttcacactga aaatcagcag ggtggaggct
      361 gaggatgttg gggtttacta ctgcatacaa tctctagagt ttccttggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01006460             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24296:16502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006460
VERSION     KCVT01006460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24296:16502"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83985.1"
                     /translation="CQQGNSIPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          107 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat tacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccca aaggtcctga
      241 tctattatgc agacagtttg tcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg taatagtatt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006461             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13956:5139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006461
VERSION     KCVT01006461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13956:5139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83986.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccagtct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggttcct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgac gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01006462             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8524:20289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006462
VERSION     KCVT01006462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8524:20289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83987.1"
                     /translation="CQQGSPFPWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          110 a          112 c          109 g           96 t
ORIGIN      
        1 acatgggggg catgagcaaa actgacaagt caaggcagga agatgttgtc tccatcacaa
       61 ctcattgggt ttctgctgct ctgggttcca gcctccaagg gtgaaattgt gctgactcag
      121 tctccagcct ttcggtctgt gactctaaag gagaaagtca ccatcacctg ccaggccagt
      181 cagagcattg gtaatagctt acactggtac cagcagaaac cggatcagtc tccaaagctc
      241 ctcatcaaat atgcttccca gtccatctca ggggtcccct caaggttcag tggcagtgga
      301 tctgggacag atttcaccct caccatcaat agcctggaag ctgaagatgc tgcgacgtat
      361 tactgtcagc agggaagtcc tttcccgtgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01006463             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21256:11068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006463
VERSION     KCVT01006463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21256:11068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..355
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83988.1"
                     /translation="CQQYDSDPFTF"
     J_segment       358..393
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           94 a          108 c          104 g           90 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag
       61 gtgccaaatg tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag
      121 acagagtcac catcacttgt cgggcgagtc agggcattcg cagttattta gcgtggtatc
      181 agcagaaacc agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg
      241 gggtcccgtc aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca
      301 gcctgcagcc tgaagatttt gcaacttatt actgtcaaca gtatgacagt gacccgttca
      361 ctttcggtgg agggaccaag gtagagatca aacgag
//
LOCUS       KCVT01006464             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15418:14416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006464
VERSION     KCVT01006464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15418:14416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83989.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgaggttcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006465             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12116:18309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006465
VERSION     KCVT01006465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12116:18309"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83990.1"
                     /translation="CQQYNSEPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          117 c          113 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg agccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006466             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16975:13426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006466
VERSION     KCVT01006466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16975:13426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83991.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgttacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagcagttat ttggcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 tttcgcgacc actttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gtagcctgca gcctgaggat tttgcatctt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccagggcacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006467             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5941:11787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006467
VERSION     KCVT01006467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5941:11787"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..371
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83992.1"
                     /translation="CQQYDSDPFTF"
     J_segment       374..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT          101 a          112 c          107 g           92 t
ORIGIN      
        1 acatgggagt caggacacag catggacatg agggtccccg ctcagctcct aggactcctg
       61 ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc atcctccctg
      121 tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg cattcgcagt
      181 tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat ctattacgcg
      241 tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagaattc
      301 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagtat
      361 gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg ag
//
LOCUS       KCVT01006468             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12339:5856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006468
VERSION     KCVT01006468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12339:5856"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83993.1"
                     /translation="CLQGYNTPVTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           96 a          115 c          121 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcgtcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattagc agttggttag cctggtatca gcagagacca gggaaagccc ctaaactcct
      241 gatctatagg gcgtccagtt tggcaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacggat tacactctca ccatcagcag cctgcagcct gaagattttg caacttattt
      361 ttgtctgcag ggttacaata ccccggtcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006469             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:3846:10581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006469
VERSION     KCVT01006469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3846:10581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83994.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgccg gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggta tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006470             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19816:12341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006470
VERSION     KCVT01006470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19816:12341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83995.1"
                     /translation="CQQYNSLPYIF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          111 c          107 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cgttttttta aattggtatc agcagaaacc ggggaaagcc cctaaacccc
      241 tgatctatta tgcaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtcaaca gtataatagt ttaccgtaca tttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006471             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9197:7122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006471
VERSION     KCVT01006471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9197:7122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83996.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          122 c          124 g          101 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccctggaga gccggcctcc gtctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatctggat tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgactt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gtatgcaagc actggagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01006472             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18608:18142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006472
VERSION     KCVT01006472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18608:18142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83997.1"
                     /translation="CMHTLEFPYTF"
     J_segment       401..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccaatgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca ggtcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcatactc tagagtttcc gtacactttt ggccagggga
      421 ccaaagtgga gatcagacga g
//
LOCUS       KCVT01006473             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:7830:2933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006473
VERSION     KCVT01006473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7830:2933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83998.1"
                     /translation="CQQYDSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgcccactt tggaaagtgg tgtcccatca aggttcagcg gcagtggttc
      301 tgggacagaa ttcactctca ccatcaacag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006474             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:9216:6360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006474
VERSION     KCVT01006474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9216:6360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV83999.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctctct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgagatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttgcactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttaatt tacgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006475             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5504:8966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006475
VERSION     KCVT01006475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5504:8966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84000.1"
                     /translation="CMQYRHIPFTF"
     J_segment       240..277
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           74 a           64 c           75 g           67 t
ORIGIN      
        1 acatgggggt ctagtcagag cctcttgaat agtgaagacg gaaacaccta tttggattgg
       61 tacctgcaga ggccgggcca gtctccacag cccttgattt atgaggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatt
      181 aacagagtgg aggctgagga tgttgggatt tatatctgca tgcaatatag acacattcca
      241 ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01006476             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13802:17161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006476
VERSION     KCVT01006476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13802:17161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84001.1"
                     /translation="CMQALEFPLTF"
     J_segment       408..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          121 c          122 g          105 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gctgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg taggtctagt
      181 cagagcctct tggatagtga ggatggaaat acctatttgg aatggcaccg gcagatgcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttcctctgac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01006477             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21806:3896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006477
VERSION     KCVT01006477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21806:3896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84002.1"
                     /translation="CQQYDSDSRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          110 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006478             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25582:9930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006478
VERSION     KCVT01006478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25582:9930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84003.1"
                     /translation="CQQDYSWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          120 c          116 g           87 t
ORIGIN      
        1 acatgggagg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 gtcttcctcc tgctactctg gatcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcatcttagc ctggtaccac cagaaacctg ggcaggctcc caagtccctc
      241 atctatggtg caaccagtag ggccaccggc atcccagaca ggttcagtgg cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg cgtttattac
      361 tgtcagcagg attatagctg gccactcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006479             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6570:21169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006479
VERSION     KCVT01006479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6570:21169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84004.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006480             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12102:12565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006480
VERSION     KCVT01006480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12102:12565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84005.1"
                     /translation="CMQGKEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          115 c          126 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tgttgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gcccttgatt tatggggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggca aagagtttcc gtacagtttt ggccagggga
      421 ccaaagtgga gatgaaacga g
//
LOCUS       KCVT01006481             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:9673:19648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006481
VERSION     KCVT01006481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9673:19648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84006.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacagt gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006482             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20139:15827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006482
VERSION     KCVT01006482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20139:15827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84007.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg agactgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01006483             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11811:22659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006483
VERSION     KCVT01006483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11811:22659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84008.1"
                     /translation="CMQSIKDPFTF"
     J_segment       399..436
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          102 a          121 c          109 g          107 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctgga tccagtgggg atattgtgat gacccagacc
      121 ccactctcgg tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctcc atagtaatgg agacacctat ttacattggt accttcagag gtcaggccag
      241 tctccacggc tcctgatcta taaagtaacc aatcgactac ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaggat
      361 attggtgttt atttctgcat gcaaagtata aaagatccat tcactttcgg ccccgggacc
      421 aaactggata tcaaacgag
//
LOCUS       KCVT01006484             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21977:15439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006484
VERSION     KCVT01006484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21977:15439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84009.1"
                     /translation="CMQTLEFPRTF"
     J_segment       406..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          100 a          123 c          121 g          100 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctggccgtc acccttggag agccggccac catctcctgc aggtctagtc
      181 agagcctctt ggctagtgag gatggaaaca cttatttgga ctggtacctt cagaggccag
      241 gccagactcc ccagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 gggtcagagg cagtgggtca gacactgagt tcacactgaa aatcagcaga gtggaggctg
      361 aggatcttgg gatttattac tgcatgcaaa ctctagagtt tcctcggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006485             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16477:12534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006485
VERSION     KCVT01006485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16477:12534"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84010.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          113 a          106 c           99 g          101 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacaaagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctaatcta
      241 ttatacaaac cgtttggaaa gtggagtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gtagtctgca atctgaagat ttttcaactt attactgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggata tcaaacgag
//
LOCUS       KCVT01006486             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20464:3023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006486
VERSION     KCVT01006486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20464:3023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..319
                     /note="immunoglobulin light chain variable region"
     V_region        8..319
     V_segment       8..284
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84011.1"
                     /translation="CQQYNSLPYTF"
     J_segment       285..319
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>325
                     /gene="IGKC"
BASE COUNT           92 a           78 c           76 g           79 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc
       61 atcacttgcc gggcaagtca ggacattggc aattatttaa attggtatca acagaaaccg
      121 gggaaagccc ctcaggtcct aatctattat gcaaaccgtt tggaaaatgg ggtcccatca
      181 aggttcagcg gcagtggatc tgggacggaa ttcactctca ccatcagcag cctgcaacct
      241 gaagattttg caattaatta ttgtcaacag tataatagtt taccgtacac ttttggccag
      301 gggaccaaag tggacatcag acgag
//
LOCUS       KCVT01006487             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:6689:12999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006487
VERSION     KCVT01006487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6689:12999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84012.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006488             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20606:12416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006488
VERSION     KCVT01006488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20606:12416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84013.1"
                     /translation="CQQGQSNPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          110 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatcc gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtga ttctttaaat tggtatcaac agaaaccggg gaaagcccct aagctcctga
      241 tattttatgc aatcagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagtagcc tgcagcctga agattttgcg acttattact
      361 gtcaacaggg tcaaagtaat cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006489             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10764:19137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006489
VERSION     KCVT01006489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10764:19137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84014.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctctcaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006490             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8645:5281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006490
VERSION     KCVT01006490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8645:5281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..349
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84015.1"
                     /translation="CLQGYIDPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           92 a          107 c          107 g           98 t
ORIGIN      
        1 acatggggtc agcatggaca tgagggtccc cgctcagctc ctggggctcc ttctgctctg
       61 gctcccaggt gccagatgtg acttccagat gacccagtct ccatcttccc tgtctgcatc
      121 ggtcggagac agagtcacca tcacttgccg ggcaagtcag gacattagcg attttttaag
      181 ttggtatcag cagaaaccag gaaaacctcc taagcgcctg atttatgctg catccagttt
      241 gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc ggcttattac tgtctacagg gttatattga
      361 cccgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01006491             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9623:17304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006491
VERSION     KCVT01006491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9623:17304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84016.1"
                     /translation="CLQYKSYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          105 a          113 c          105 g          100 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtta catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccgt cacttgccgg gcaagtcagg
      181 atattagcac ttatttaaat tggtttcagc agaaaccagg gaaagcccct agactcctga
      241 tctatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttatcact
      361 gtctacaata taaaagttac cctctcactt tcggcggggg gaccaaggtg gagatcaaaa
      421 gag
//
LOCUS       KCVT01006492             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:3918:13131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006492
VERSION     KCVT01006492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3918:13131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84017.1"
                     /translation="CQQSYRYPLTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          107 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacactggt atcagcagaa accagggaaa gcccctaaac tcctgatgta
      241 tcttgcatcc actttgcaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcgccatca gcagcctgca gcctgaagat gctgcaactt attactgtca
      361 gcagagttat cgttatccgc tcactttcgg tggagggacc caggtggaaa tcaatcgag
//
LOCUS       KCVT01006493             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6796:16245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006493
VERSION     KCVT01006493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6796:16245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84018.1"
                     /translation="CQQYNSGPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          115 c          104 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct tcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagag accaggcaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc gttttggaga atggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtggcccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006494             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:20704:9925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006494
VERSION     KCVT01006494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20704:9925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84019.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgagac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006495             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9611:19782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006495
VERSION     KCVT01006495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9611:19782"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84020.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          107 c          107 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ttccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagtttt ttaaattggt atcagcagaa accggggaaa gcccctaagg ccctgatcta
      241 ttatgcaaac cggttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca atctgaagat tttgcaactt attactgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtagaga tcaaacgag
//
LOCUS       KCVT01006496             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12843:19777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006496
VERSION     KCVT01006496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12843:19777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84021.1"
                     /translation="CQQHDNFPYIF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          116 c          104 g           93 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcaa
      181 catattagcg actggttggc ctggtatcaa cagaaaccag ggaaagcccc taagctcctg
      241 atctatcggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc tttcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgataattt cccgtacatt tttgaccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006497             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:26114:8709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006497
VERSION     KCVT01006497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26114:8709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84022.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          115 c          107 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagtagttct ttacattggt ttcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcactg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgctactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006498             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21677:4437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006498
VERSION     KCVT01006498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21677:4437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84023.1"
                     /translation="CQHSYDTPYTF"
     J_segment       380..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          105 g           95 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgcgaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gtccctgagc tcctgatcta
      241 tgctgcatcg tctttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcacc ctcaccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcatagttat gataccccct acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006499             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15870:6332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006499
VERSION     KCVT01006499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15870:6332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..388
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84024.1"
                     /translation="CLQFKTFPYSF"
     J_segment       389..426
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           99 a          119 c          109 g          102 t
ORIGIN      
        1 acatgggggg caggagtcag acacagtcag gacacagcat ggacatgagg gcccccgctc
       61 atctcctagg gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc
      121 agtctccatc ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa
      181 gtcagggtat tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc
      241 tcctcatcta tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg
      301 gatctgggac agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt
      361 attactgtct acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga
      421 tcaaacgag
//
LOCUS       KCVT01006500             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:23714:16822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006500
VERSION     KCVT01006500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23714:16822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84025.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          125 c          117 g           84 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gctgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc tcccagactc
      241 ctcatctatg gtgcatccaa cagggccact ggcggcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcactttat
      361 tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006501             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6044:10295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006501
VERSION     KCVT01006501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6044:10295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84026.1"
                     /translation="CMQAREFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg actacccaga
      121 ctccagtctc cctgcccgtc actcttggag agccggcctc catctcctgc atgtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatgtgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctcgagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006502             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22189:8435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006502
VERSION     KCVT01006502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22189:8435"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84027.1"
                     /translation="CQQGYNYPWTF"
     J_segment       379..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT          100 a          116 c          107 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatctct tgccaggcga gtcaaggcat
      181 tgacaataat ttaaattggt ttcagcagac accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat aattacccgt ggacgttcgg ccaagggacc aaggtggaaa tccaacgag
//
LOCUS       KCVT01006503             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:7879:13982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006503
VERSION     KCVT01006503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7879:13982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84028.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006504             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17352:14211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006504
VERSION     KCVT01006504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17352:14211"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84029.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          118 c          125 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccgca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaatt cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006505             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12358:16877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006505
VERSION     KCVT01006505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12358:16877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84030.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcatcc ttggagagcc ggcctccata tcctgcacgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattattgca tgcaagctct agagtttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006506             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23670:20588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006506
VERSION     KCVT01006506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23670:20588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84031.1"
                     /translation="CQQYDSDSLSF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          113 c          110 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgga gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcagtttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006507             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14599:15799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006507
VERSION     KCVT01006507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14599:15799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84032.1"
                     /translation="CQQYNSYPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          105 g           97 t
ORIGIN      
        1 acatggggaa tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtgggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcag ttatttagcc tggtatcagc agaaaccagg gaaagcccct aagcgcctga
      241 tctatgctgc atccactttg caaagtgggg tcccatcaag attcagcggc agtggatctg
      301 tgacagattt cactctcacc atcagcagcc tacagcctga agattttgca acttattact
      361 gtcaacagta taatagttat ccgctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006508             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:17016:15294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006508
VERSION     KCVT01006508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17016:15294"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84033.1"
                     /translation="CGQGTHLPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          100 a          120 c          119 g           95 t
ORIGIN      
        1 acatggggga ctgatcagga ctcctcagtt caccatgagg ctccctgctc agctcctggg
       61 gctgctattg ctctgcgtcc ccggatccag tggggatgtt gtgatgactc agtctccact
      121 ctccctgtcc atcacccctg gacagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tgtacacatc aatggaaaca catacttgag ttggtatcag cagaacccag gccaacctcc
      241 aaggcgccta atttatgagg tttctaaccg ggactctggg gtcccagaca gattcagcgg
      301 cagtggggca gggacagatt tcacactgaa aatcagcaga gtggaggctg aggatgttgg
      361 gctttattac tgcgggcaag gtacacacct tccgtggacg ttcggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01006509             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19224:13332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006509
VERSION     KCVT01006509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19224:13332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84034.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          123 c          117 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggtctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgataa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cattcacctt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01006510             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:4819:10522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006510
VERSION     KCVT01006510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4819:10522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    174..328
                     /note="immunoglobulin light chain variable region"
     V_region        174..328
     V_segment       174..287
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <270..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84035.1"
                     /translation="CQQSYRYPLTF"
     J_segment       293..328
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>333
                     /gene="IGKC"
BASE COUNT           72 a           94 c           93 g           74 t
ORIGIN      
        1 acatgggggg gagtcagtct cagtcaggac acagcatgga catgagggcc tctgctcagc
       61 tcctagggct cctgctgctc tggctcccag gcgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc aggagtgggg
      181 tcccatcaag gttcagcggc agtggatctg ggacagattt cactctcgcc atcagcagcc
      241 tgcagcctga agatgctgca acttattact gtcagcagag ttatcgttat ccgctcactt
      301 tcggtggagg gacccaggtg gaaatcaatc gag
//
LOCUS       KCVT01006511             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:22265:9913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006511
VERSION     KCVT01006511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22265:9913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    46..367
                     /note="immunoglobulin light chain variable region"
     V_region        46..367
     V_segment       46..330
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84036.1"
                     /translation="CQQGNSNPLTF"
     J_segment       331..367
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           92 a           90 c           99 g           89 t
ORIGIN      
        1 acatgggggg ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgtcc
       61 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca
      121 agtcagggca ttagtagtta tttaaattgg tatcagcaga gaccggggaa agcccctaag
      181 ctcctgatct attatgcaaa gagtttggca agtggggtcc catcaaggtt cagcggcagt
      241 ggatctggga cagaattcac tctcacaatc agtagcctgc agcctgaaga ttttgcaact
      301 tattactgtc aacagggtaa tagtaatcct ctcactttcg gcggagggac caaggtggag
      361 atcaaacgag
//
LOCUS       KCVT01006512             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22117:12565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006512
VERSION     KCVT01006512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22117:12565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84037.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cattctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccaggcaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gagactgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01006513             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25464:10947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006513
VERSION     KCVT01006513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25464:10947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84038.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          123 c          117 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atacctccgg agatatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacagaaacc tgggcaggct cccaggctcc
      241 tcctctttgg tgcaaccaac agggccactg gcatcccaga caggttcagt ggcggtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006514             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10172:16535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006514
VERSION     KCVT01006514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10172:16535"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..398
                     /note="immunoglobulin light chain variable region"
     V_region        77..398
     V_segment       77..359
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84039.1"
                     /translation="CQQYNSDLFTF"
     J_segment       363..398
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>401
                     /gene="IGKC"
BASE COUNT           97 a          106 c          104 g           94 t
ORIGIN      
        1 acatgggagc atggacatga gggtccccgc tcagctccta ggactcctgc tgctctgtct
       61 cccaggtgcc aaatgtgaca tccagatgac ccagtctcca tcctccctgt ctgcatttgt
      121 aggagacaga gtcaccatca cttgtcgggc gagtcagggc attcgcagtt atttagcgtg
      181 gtatcagcag aaaccaggga aagccccgaa gcccttgatc tattacgcgt ccattttgga
      241 aagtggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat
      301 cagcagcctg cagcctgaag attttgcaac ttattactgt caacagtata acagtgacct
      361 gttcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006515             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18189:6221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006515
VERSION     KCVT01006515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18189:6221"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..446
                     /note="immunoglobulin light chain variable region"
     V_region        125..446
     V_segment       125..408
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84040.1"
                     /translation="CHQGNSFPWTF"
     J_segment       409..446
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>449
                     /gene="IGKC"
BASE COUNT          114 a          112 c          116 g          107 t
ORIGIN      
        1 acatggggag aggctctttc tctgggatgt ggcatgagca aaactgacaa gtcaaggcag
       61 gaagatgttg tctccatcac aactcattgg gtttctgctg ctctgggttc cagcctccaa
      121 gggtgaaatt gtgctgactc agtctccagt ctttcggtct gtgactctaa aggagaaagt
      181 caccatcacc tgccaggcca gtcagaacat tggtaataag ctacactggt accagcagaa
      241 accggatcag tctccgaagc tcctcatcaa gtatgcttcc cagtccatct caggggtccc
      301 ctcaaggttc agtggcagtg gatctgggac agatttcacc cttaccatca atagcctgga
      361 agctgaagat gctgcgacgt attactgtca ccagggtaat agttttccgt ggacgttcgg
      421 ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006516             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6069:6171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006516
VERSION     KCVT01006516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6069:6171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..415
                     /note="immunoglobulin light chain variable region"
     V_region        98..415
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84041.1"
                     /translation="CQQGYSYHPTF"
     J_segment       385..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>422
                     /gene="IGKC"
BASE COUNT           93 a          120 c          109 g          100 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac ttccttatga cgcagtctcc
      121 ttcctccctg tccgcatctg taggagacac agtcaccatc acttgccagg cgagtcaagc
      181 cattggcact aatttaaatt ggtatcagca gagaccagga aaagccccta aactcctgat
      241 ctatagggct tccggtttgc agagtgggac tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc agtctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatagttacc atcccacttt cggcggaggg accaaggtgg agatccaacg
      421 ag
//
LOCUS       KCVT01006517             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:20791:19987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006517
VERSION     KCVT01006517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20791:19987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84042.1"
                     /translation="CQQYDSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          115 c          113 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcttggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattagc agttatttag cgtggtatca gcagaagcca gggaaagccc cgaagccctt
      241 gatctatttc gcatccattt tggaaagtgg cgtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctcg ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006518             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18167:15865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006518
VERSION     KCVT01006518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18167:15865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..285
                     /note="immunoglobulin light chain variable region"
     V_region        5..285
     V_segment       5..247
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <225..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84043.1"
                     /translation="CLQGYITPYSF"
     J_segment       248..285
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>288
                     /gene="IGKC"
BASE COUNT           77 a           67 c           76 g           68 t
ORIGIN      
        1 acatgggagg agacagagtc accatcactt gccgggcaag tcaggacatt agcgattttt
       61 taagttggta tcagcagaaa ccaggaaaac ctcctaagcg cctgatttat gctgcatcca
      121 gtttgcaaag tggggtcccg tcaaggttca gcggcagtgg atctgggaca gaattcactc
      181 tcaccatcag cagcctgcag cctgaagatt ttgcggctta ttactgtcta cagggttata
      241 ttaccccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01006519             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11606:20489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006519
VERSION     KCVT01006519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11606:20489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84044.1"
                     /translation="CQQGNSNPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          110 c          109 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgtcc cagtttccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcaggcca
      181 ttagcagtta tttaaattgg tatcagcaga aaccggggaa agcccctaaa ctcctgatat
      241 actatggaaa aagtttggca agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc accagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagggtaa tagtaatcct ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006520             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:24188:11067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006520
VERSION     KCVT01006520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24188:11067"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84045.1"
                     /translation="CFQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagcgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc tttcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006521             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10688:19531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006521
VERSION     KCVT01006521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10688:19531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84046.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac atagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01006522             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16386:6742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006522
VERSION     KCVT01006522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16386:6742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84047.1"
                     /translation="CMQTTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           98 a          125 c          109 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaactacaa aagatcccct cactttcggc cccgggacca
      421 acctggattt caaacgag
//
LOCUS       KCVT01006523             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:7414:20418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006523
VERSION     KCVT01006523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7414:20418"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84048.1"
                     /translation="CQQYNSLPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgcta ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcaa gtcagggcat
      181 tagcgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgtaggtt attactgtca
      361 acagtataat agtttaccgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006524             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:12402:17004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006524
VERSION     KCVT01006524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12402:17004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..275
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84049.1"
                     /translation="CQQYNSDPFTF"
     J_segment       276..313
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           85 a           80 c           76 g           75 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgca tctgtaggag acagagtaac tatcacttgt
       61 cgggcgagtc aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaagcc
      121 ccgaagccct tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt
      181 ggcagtggat ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt
      241 gcaacttatt actgtcaaca gtataacagt gacccattca ctttcggccc cgggaccaaa
      301 ctggatacca aacgag
//
LOCUS       KCVT01006525             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12256:7110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006525
VERSION     KCVT01006525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12256:7110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84050.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          115 c          104 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaagcagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006526             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16471:15691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006526
VERSION     KCVT01006526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16471:15691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84051.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          122 c          121 g          107 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca atcgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01006527             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15476:4525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006527
VERSION     KCVT01006527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15476:4525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84052.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggtctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006528             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20641:3927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006528
VERSION     KCVT01006528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20641:3927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84053.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006529             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11750:4131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006529
VERSION     KCVT01006529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11750:4131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84054.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac gactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006530             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:23861:12093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006530
VERSION     KCVT01006530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23861:12093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84055.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctctcgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006531             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12051:11887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006531
VERSION     KCVT01006531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12051:11887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84056.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          111 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc accagaagcc tgggcaggct cccaagctcc
      241 tcatctatgg tccatccatc agggccagcg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga atttactctc accatcagca gcctggagac tgaagatatt ggagtttatt
      361 tctgtcagca ggattatcac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006532             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16891:10937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006532
VERSION     KCVT01006532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16891:10937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84057.1"
                     /translation="CQQHDNSPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          115 c          111 g           86 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagagta
      181 ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga taattccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006533             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14788:9119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006533
VERSION     KCVT01006533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14788:9119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84058.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          118 c          107 g           89 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagtcag
      181 gatattaata cctggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctg
      241 atctatatgg catccaattt ggaaacaggg gtcccatcga ggttcggtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006534             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13005:7263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006534
VERSION     KCVT01006534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13005:7263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84059.1"
                     /translation="CQQHDNAPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          113 g           84 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcagc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcagcagca tgacaatgcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006535             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:6230:14935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006535
VERSION     KCVT01006535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6230:14935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84060.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          124 c          114 g           86 t
ORIGIN      
        1 atgggggagg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcttagc ctggtaccaa caaaaacctg ggcaggctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtctatttt
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006536             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24928:9062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006536
VERSION     KCVT01006536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24928:9062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84061.1"
                     /translation="CQQYDSDSLIF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga ggcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaatat gacagtgatt cgctcatttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006537             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16027:2957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006537
VERSION     KCVT01006537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16027:2957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84062.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           92 a          122 c          126 g          105 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagcg gggacattgt gatgacccag
      121 actcctctct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatggtga ggatggaaac acctacttgg aatggtattt gcagaagcca
      241 ggccagtctc cgcagctctt gatttatgcg gtttccaagc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc aggcactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatca ctgcatgcaa gctctagagt ttcctctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01006538             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25688:16176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006538
VERSION     KCVT01006538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25688:16176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84063.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc actggggaca ttgtgctgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagaac
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga gcctgaggat
      361 gttggggttt attactgcat gcaagctcta gaatttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01006539             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16611:20941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006539
VERSION     KCVT01006539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16611:20941"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84064.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacacagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006540             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:21238:12555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006540
VERSION     KCVT01006540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21238:12555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..332
                     /note="immunoglobulin light chain variable region"
     V_region        11..332
     V_segment       11..295
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <272..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84065.1"
                     /translation="CQQDFDWPPTF"
     J_segment       298..332
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>335
                     /gene="IGKC"
BASE COUNT           77 a           96 c           92 g           70 t
ORIGIN      
        1 acatggggga gaagttgtga tgacgcagtc tccagccacc ctgtctttgt ctccagggga
       61 aagagccacc ctctcctgca gggccagtca gagtgttggc aacaccttaa cctggtacca
      121 gcacaaacct gggcaggctc ccaagctcct cctctatggt gcatccacca gggcctccgg
      181 catcccaggc aggttcagtg ccagtgggtc tggaacagag tttactctca ccatcagcag
      241 cctggagcct gaagatgttg gaatttatta ctgtcagcag gattttgact ggcctccgac
      301 gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01006541             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18768:10501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006541
VERSION     KCVT01006541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18768:10501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84066.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          116 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006542             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12144:24438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006542
VERSION     KCVT01006542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12144:24438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84067.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggtcagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006543             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11778:10583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006543
VERSION     KCVT01006543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11778:10583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84068.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           88 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagctga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagtcagga
      181 tattaatacc tggttggcct ggtatcaaca gaaaccagga aaagccccta aactcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcggtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaagcg
      421 ag
//
LOCUS       KCVT01006544             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11600:7745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006544
VERSION     KCVT01006544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11600:7745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84069.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cgaaccgggc ctctggagcc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006545             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14415:3664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006545
VERSION     KCVT01006545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14415:3664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84070.1"
                     /translation="CQQYNSYPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          119 c          109 g           98 t
ORIGIN      
        1 acatggggga atcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattgaca gttatttagc ctggtttcag cagaaacctg ggaaagcccc taagcgcctg
      241 atctatactg catccacttt gcagcgtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttatttc
      361 tgtcaacagt ataatagtta cccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006546             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15915:16858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006546
VERSION     KCVT01006546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15915:16858"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84071.1"
                     /translation="CQQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          110 c          101 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 actcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtatttat ttaaattggt atcaacaaaa accggggaaa gcccctaagc tcctgatcta
      241 ttatggaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataac agtttaccgt acacttttgg ccacgggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006547             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17747:4442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006547
VERSION     KCVT01006547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17747:4442"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..341
                     /note="immunoglobulin light chain variable region"
     V_region        8..341
     V_segment       8..304
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84072.1"
                     /translation="CMQALEFPLTF"
     J_segment       305..341
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           79 a           87 c           97 g           81 t
ORIGIN      
        1 acatggggtg atgacccaga ctccactctc cctgcccgtc acccttggag agccggcctc
       61 catctcctgc aggtctagtc agagcctctt ggatggtgag gatggaaaca cctatttgga
      121 atggtacctg cagaagccag gccagtctcc acagctcttg atttatgagg tttccaaccg
      181 ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa
      241 aatcagcaga gtggaggctg aggatgttgg gatttattac tgcatgcaag ctctagagtt
      301 tcctctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006548             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:16290:15570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006548
VERSION     KCVT01006548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16290:15570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..413
                     /note="immunoglobulin light chain variable region"
     V_region        99..413
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84073.1"
                     /translation="CQQYNTLPLTF"
     J_segment       383..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcagc agaaaccggg gaaagcccct gagctcctga
      241 tctattatgc aaaccgtttg gaaactgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttattact
      361 gtcaacagta taatacttta ccgctcactt tcggcggagg gaccaaggtg gaggtcagac
      421 gag
//
LOCUS       KCVT01006549             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16458:6020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006549
VERSION     KCVT01006549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16458:6020"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84074.1"
                     /translation="CQQYNYLPRTF"
     J_segment       386..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          109 a          113 c          106 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagtc aatatttaaa ttggtatcag cagaaaccgg ggaaagcccc taacctcctc
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc aacttattac
      361 tgtcaacagt ataattattt acctcggacg ttcggccaag ggaccaaggt ggaaatcaga
      421 cgag
//
LOCUS       KCVT01006550             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15146:8912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006550
VERSION     KCVT01006550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15146:8912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..400
                     /note="immunoglobulin light chain variable region"
     V_region        63..400
     V_segment       63..364
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <342..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84075.1"
                     /translation="CMQSLDFPLTF"
     J_segment       365..400
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>405
                     /gene="IGKC"
BASE COUNT           89 a          109 c          112 g           95 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct ggatccagtg
       61 cggacattgt tatgacccag actccactct ccctgcccgt cacccttgga gagccggcct
      121 ccatctcctg caggtctagt cagagcctcc tggatagtga ggatggaaac acctatttgg
      181 aatggtacct gcagaagcca ggccagtctc cacagctctt gatttatgag gtttccagcc
      241 gggcctctgg agtcccagac aggttcagtg gcagcgggtc agacacagat ttcacactga
      301 gaatcagcag agtggaggct gaggatgttg gggtttatta ctgcatgcag tctctagatt
      361 ttccgctcac tttcggtgga gggaccaagg tggagatcaa tcgag
//
LOCUS       KCVT01006551             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15638:18665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006551
VERSION     KCVT01006551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15638:18665"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84076.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          122 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcaa aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcaaagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccgcggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006552             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14786:22226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006552
VERSION     KCVT01006552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14786:22226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84077.1"
                     /translation="CQQYNSLPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          109 c          108 g           98 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctc tgggggacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaga tatttaaatt ggtatcagca gaaaccgggg aaagccccta agttcctgat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattattg
      361 tcaacagtat aatagtttac cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006553             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:23364:8678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006553
VERSION     KCVT01006553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23364:8678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..390
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84078.1"
                     /translation="CGQGTQLPPTF"
     J_segment       394..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g           95 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atttcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcaccaga agacaggcca acctccaagg
      241 cgcctaattt atgaggtttc tatccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaagatc agcagagtgg aggctgagga tgttggggtt
      361 tattactgcg ggcaaggtac acagcttcct cccacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01006554             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12623:17430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006554
VERSION     KCVT01006554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12623:17430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84079.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg ctccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01006555             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:5334:12176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006555
VERSION     KCVT01006555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5334:12176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84080.1"
                     /translation="CQQYNNDPPTF"
     J_segment       382..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          122 c          102 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tggcagtcat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac aatgaccctc ccactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006556             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11160:8189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006556
VERSION     KCVT01006556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11160:8189"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..431
                     /note="immunoglobulin light chain variable region"
     V_region        113..431
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84081.1"
                     /translation="CQQYITSPFTF"
     J_segment       397..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>437
                     /gene="IGKC"
BASE COUNT           98 a          132 c          112 g           95 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat
      121 cttgactcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ttcatctatg gtgcatccag cagggccact ggcatccccg acagattcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcagtgtat tactgtcagc agtatattac ctccccattc actttcggcc ccgggaccaa
      421 actggatatc agacgag
//
LOCUS       KCVT01006557             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19565:15678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006557
VERSION     KCVT01006557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19565:15678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84082.1"
                     /translation="CQQSYRYPLTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          100 a          112 c          110 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaagc tcctggtgta
      241 tcttgcatcc aatttgcaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcgccatca gcagcctgca gcctgaagat gttgcaactt attactgtca
      361 gcagagttat cgttatccgc tcactttcgg tggagggacc caggtggaaa tcaatcgag
//
LOCUS       KCVT01006558             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14228:8208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006558
VERSION     KCVT01006558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14228:8208"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84083.1"
                     /translation="CMQYTHMPLTF"
     J_segment       401..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT          100 a          121 c          119 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaagat ggaaacacct atttggattg gtacctacaa aagccgggcc
      241 agccgccaca gcccttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaatata cacacatgcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcgaacga g
//
LOCUS       KCVT01006559             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20901:14349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006559
VERSION     KCVT01006559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20901:14349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84084.1"
                     /translation="CMQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          121 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttatttctgc atgcaaagtc tggagtttcc ttggacgttc gaccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006560             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21290:11002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006560
VERSION     KCVT01006560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21290:11002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84085.1"
                     /translation="CQQGNSNPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          110 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtttccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggccat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatata
      241 ctatggaaaa agtttggcaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagggtaat agtaatcctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006561             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8308:13343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006561
VERSION     KCVT01006561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8308:13343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84086.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          108 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006562             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6497:3617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006562
VERSION     KCVT01006562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6497:3617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84087.1"
                     /translation="CQQHNTYPYTF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          120 c          104 g           91 t
ORIGIN      
        1 acatggggca gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtccca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ctagtaatga tttagcctgg tatcagcaga aaccagggaa agccccgaag cccctgatct
      241 tttacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagcataa tacttacccg tacacttttg gccaggggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006563             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16538:11682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006563
VERSION     KCVT01006563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16538:11682"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84088.1"
                     /translation="CMQARDFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          126 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccattgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt cgatagtgag gaaggaaaca cctatttgga gtggtacctg cagaggccag
      241 gccagtctcc acaggtcttg atttatgggg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgag aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctcgagactt tccattcact ttcggccccg
      421 ggaccaaact ggacatcaaa cgag
//
LOCUS       KCVT01006564             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21231:14176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006564
VERSION     KCVT01006564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21231:14176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84089.1"
                     /translation="CMEALEFPYTF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tgttgaggat ggaaacacct atttggaatg gcacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atggaagctc tagaatttcc ctacactttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006565             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23878:13037
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006565
VERSION     KCVT01006565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23878:13037"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..449
                     /note="immunoglobulin light chain variable region"
     V_region        122..449
     V_segment       122..405
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84090.1"
                     /translation="CQQRNSYPYIYSF"
     J_segment       413..449
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>452
                     /gene="IGKC"
BASE COUNT          107 a          117 c          121 g          107 t
ORIGIN      
        1 acatggggag gctggttaca cttcgtgcag gagttagacc cagtctggac gcagcatgga
       61 catcagggtc ctcgctcagc ttctcgggct cctgctgctc tggctcccag gtgccagatg
      121 tgacattcag ttgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcaagtc aggacattag cagttcttta gcctggtatc agcagaaacc
      241 agggaaagcc cctaaggtcc tgatctataa ggcgtccagt ttgcaaagtg gggtcccttc
      301 aaggttcagc ggcagtggat ctgggacaga agtcactctc accatcagca gcctgcaggc
      361 tgaagatttt gcagtttatt actgtcaaca gcgtaatagt tacccgtaca tatacagttt
      421 tggccagggg accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01006566             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14520:3469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006566
VERSION     KCVT01006566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14520:3469"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84091.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006567             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11453:10150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006567
VERSION     KCVT01006567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11453:10150"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84092.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          124 c          115 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtat caacaaaaac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgc tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006568             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19955:13893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006568
VERSION     KCVT01006568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19955:13893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84093.1"
                     /translation="CMQGLEFPITF"
     J_segment       404..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggtg atcaggactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tgatgctctg ggtccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc caatcacttt cggccccggg
      421 accaaactgg atatcaaacg ag
//
LOCUS       KCVT01006569             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17794:6864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006569
VERSION     KCVT01006569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17794:6864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84094.1"
                     /translation="CQQYNTLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          109 c          108 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gatatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagttcctg
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattat
      361 tgtcaacagt ataatacttt accgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006570             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:28001:8133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006570
VERSION     KCVT01006570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:28001:8133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84095.1"
                     /translation="CQQGYTPPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          118 c          114 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgtgtc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattagca gctggttagc ctggtatcag caggaaccag ggaaagcccc taaactcctg
      241 atctataagg cgtccagttt ggcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacggatt acactctcac catcaacagc ctgcagcctg aagattttac aacttattat
      361 tgtcaacagg gttacactcc ccctctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006571             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17247:14162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006571
VERSION     KCVT01006571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17247:14162"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84096.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggt tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcatgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tgtggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006572             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:28902:11873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006572
VERSION     KCVT01006572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:28902:11873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..417
                     /note="immunoglobulin light chain variable region"
     V_region        78..417
     V_segment       78..380
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84097.1"
                     /translation="CMQALEFPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           93 a          112 c          115 g          100 t
ORIGIN      
        1 acatgggcct tctcacaatg aggctccctg ctcagctcct gggactgcta atgctctggc
       61 tccctggatc cagcggggac attgtgatga cccagactcc actctccctg cccgtcaccc
      121 ttggagagcc ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg
      181 gaaacaccta tatggaatgg tacctgcaga agccaggcca gtctccacag ctcttgattt
      241 atgaggtttc catacgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca
      301 ctgatttcac actgaaaatc agtagagtgg aggctgagga tgttgggatt tattactgca
      361 tgcaagctct agagtttcct ctcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006573             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16758:13140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006573
VERSION     KCVT01006573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16758:13140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84098.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgt agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006574             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9550:18046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006574
VERSION     KCVT01006574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9550:18046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84099.1"
                     /translation="CQQHNSYPLTF"
     J_segment       385..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          106 a          121 c          107 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacca atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaactggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatagtta cccactcact ttcggcggag ggaccaaggt ggagatcaga
      421 cgag
//
LOCUS       KCVT01006575             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13795:15690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006575
VERSION     KCVT01006575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13795:15690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84100.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          120 c          106 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006576             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22856:11002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006576
VERSION     KCVT01006576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22856:11002"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84101.1"
                     /translation="CQQYNSDWRTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          114 g           92 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gactggcgca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006577             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18013:5412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006577
VERSION     KCVT01006577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18013:5412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84102.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagcccc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006578             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15784:7888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006578
VERSION     KCVT01006578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15784:7888"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84103.1"
                     /translation="CQQYNSLPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          109 c          107 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatta cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagttat tatttaaatt ggtatcaaca gaaaccgggg aaagccccta aggtcctgat
      241 ctattacaca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa gttattactg
      361 tcaacaatat aatagtttac cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006579             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20441:16021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006579
VERSION     KCVT01006579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20441:16021"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84104.1"
                     /translation="CQQYDSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          114 c          108 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcaa ttatttaaat tggtatcagg agaaaccggg gaaagcccct aagcccctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtagatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttactact
      361 gtcaacagta tgattcttta ccgtggacgt tcggccaagg gaccaaggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01006580             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24429:6316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006580
VERSION     KCVT01006580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24429:6316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84105.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctcccca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006581             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13517:11179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006581
VERSION     KCVT01006581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13517:11179"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84106.1"
                     /translation="CMQALEFPLTF"
     J_segment       348..384
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           87 a           97 c          110 g           93 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcactcttg gagagccggc ctccatctcc tgcaggtcta
      121 gtcagagcct cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaaac
      181 caggccagtc tccacgactc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggttcag tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg
      301 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttcctctc actttcggtg
      361 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006582             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:25460:8461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006582
VERSION     KCVT01006582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25460:8461"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84107.1"
                     /translation="CMQSLEIPPTF"
     J_segment       401..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           90 a          120 c          125 g          103 t
ORIGIN      
        1 acatggggga cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc cagactccac
      121 tctccctgcc cgtcaccctt ggagagccgg cctccatctc ctgcaggtcg agtcagagcc
      181 tcttggatgg tggggatgga aacacctatt tggattggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagccact gatttcacac tgaaaatcag cagggtggag gctgaggatg
      361 ttggggtttg ttactgcatg caatctctag agattcctcc cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01006583             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10224:10876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006583
VERSION     KCVT01006583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10224:10876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..390
                     /note="immunoglobulin light chain variable region"
     V_region        69..390
     V_segment       69..348
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <330..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84108.1"
                     /translation="CQQYDSDSLTF"
     J_segment       353..390
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>393
                     /gene="IGKC"
BASE COUNT           94 a          108 c          100 g           91 t
ORIGIN      
        1 acatgggcat gagggtcccc gctcagctcc taggactcct gctgctctgt ctcccaggtg
       61 ccaaatgtga catccagatg acccagtctc catcctccct gtctgcatct gtaggagaca
      121 gagtcaccat cacttgtcgg gcgactcagg acattcgcag ttatttagcg tggtatcagc
      181 agaaaccagg gaaagccccg aagcccttga tctattacgc gtccactttg gaaagtgggg
      241 tcccatcaag gttcagcggc agtggatctg ggacagaatt cactctcacc atcagcagcc
      301 tgcagcctga agattttgca acttattact gtcaacagta tgacagtgat tcgctcactt
      361 tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01006584             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:18550:8187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006584
VERSION     KCVT01006584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18550:8187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84109.1"
                     /translation="CQQYDSDTRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          114 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cacgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006585             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10825:5385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006585
VERSION     KCVT01006585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10825:5385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..367
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84110.1"
                     /translation="CQQYDDYPWTF"
     J_segment       379..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacaaagt caccatcact tgccatgcca gtcagggtat
      181 tagtagtcgg ttagtctggt atcagcagaa agcagggaaa gcccctaagc ccctgatgta
      241 tgatgcatcc agtttacaca gtggcatccc atcaaggttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgctactt attactgtca
      361 acagtatgat gattacccgt ggaccttcgg ccaagggacc aaggtggaaa tcaagcgag
//
LOCUS       KCVT01006586             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18077:3477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006586
VERSION     KCVT01006586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18077:3477"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84111.1"
                     /translation="CQQYNRLPRTF"
     J_segment       384..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>422
                     /gene="IGKC"
BASE COUNT          108 a          110 c          110 g           94 t
ORIGIN      
        1 atgggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagtcaa tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctcat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa cttattactg
      361 tcaacagtat aatagattac ctcggacgtt cggccaaggg accaaggtgg aaatcagacg
      421 ag
//
LOCUS       KCVT01006587             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:25442:9670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006587
VERSION     KCVT01006587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:25442:9670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84112.1"
                     /translation="CMQYRHIPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           98 a          118 c          113 g          108 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgaag ctccctgctc agctcctggg
       61 gctgctaatg ctctggctct ctggttccag tggggatgtt gtgatgaccc agactccatt
      121 ctccctgtcc gttagccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttgaatagt gaagacggaa acacctattt ggattggtac ctgcagaggc cgggccagtc
      241 tccacagccc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaattaac agagtggagg ctgaggatgt
      361 tgggatttat atctgcatgc aatatagaca cattccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01006588             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:5948:15980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006588
VERSION     KCVT01006588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:5948:15980"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84113.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          116 c          104 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01006589             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14849:16083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006589
VERSION     KCVT01006589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14849:16083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84114.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tgtcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006590             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15993:12167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006590
VERSION     KCVT01006590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15993:12167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..247
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84115.1"
                     /translation="CQQNSNWPLTF"
     J_segment       248..284
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           72 a           75 c           83 g           57 t
ORIGIN      
        1 acatggggga gaaagagcca ccctctcctg cagggccagt cagagtgtca gcagcagtgt
       61 agcctggtac cagcaaaaac ctgggcaggc tcccagactc ctcatctatg gtgcatccaa
      121 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcagtct
      181 caccatcagc agcctggagc ctgaagatgt tgcactttat tattgtcagc agaatagtaa
      241 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006591             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:9634:7913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006591
VERSION     KCVT01006591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9634:7913"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..362
                     /note="immunoglobulin light chain variable region"
     V_region        44..362
     V_segment       44..325
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84116.1"
                     /translation="CQQYNTLITF"
     J_segment       327..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           96 a           93 c           89 g           87 t
ORIGIN      
        1 acatgggggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
       61 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcgctt gccgggcaag
      121 tcaggacata agtaattatt taaattggta tcagcagaaa ccggggaaag cccctaagct
      181 cctgatctat tacacaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaactta
      301 tttctgtcaa cagtataaca ctttaatcac tttcggcggg ggaaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01006592             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16316:13483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006592
VERSION     KCVT01006592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16316:13483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84117.1"
                     /translation="CLQYKSYPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          114 c           99 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gcaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 gtattagtac ctatttaaat tggtttcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatgctgc atctagtctg gaaagtgggg tcccatcaag gttcagcggc agtggatttg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtctacagta taaaagttat ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006593             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12948:13998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006593
VERSION     KCVT01006593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12948:13998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84118.1"
                     /translation="CQHSFDTPYTF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          118 c          107 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtgcga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagtccct gagctcctga
      241 tctatgctgc atcgtctttg caaagtgggg tcccatcaag gttcagcggc agtgggtctg
      301 ggacagattt caccctcacc atcagcagcc tgcagcctga agatgttgca acttattact
      361 gtcagcacag ttttgatacc ccctacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006594             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:5129:7348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006594
VERSION     KCVT01006594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5129:7348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84119.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          121 c          120 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggctc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgctggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga ggccaggcca
      241 ctctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgta tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006595             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20861:9488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006595
VERSION     KCVT01006595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20861:9488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    17..338
                     /note="immunoglobulin light chain variable region"
     V_region        17..338
     V_segment       17..300
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84120.1"
                     /translation="CQQYDSDPLTF"
     J_segment       301..338
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>341
                     /gene="IGKC"
BASE COUNT           88 a           88 c           88 g           77 t
ORIGIN      
        1 acatggggcc aaatgtgaca tccagatgac ccagtctcca tcctccctgt ctgcatctgt
       61 aggagacaga gtcaccatca cttgtcgggc gagtcagggc attcgcagtt atttagcgtg
      121 gtatcagcag aaaccaggga aagtcccgaa gcccttgatc tattacgcgt ccactttgga
      181 aagtggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca ctctcaccat
      241 cagcagcctg cagcctgaag attttgcaac ttattactgt caacagtatg acagtgaccc
      301 gctcactttc ggtggaggga ccaaggtaga gatcaaacga g
//
LOCUS       KCVT01006596             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:8669:8262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006596
VERSION     KCVT01006596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8669:8262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84121.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          106 t
ORIGIN      
        1 atggggactg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tattgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcatgg atagtgggga tgtaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac atctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacggatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtacagttt tggccagggg
      421 accagagtgg agatcaaacg ag
//
LOCUS       KCVT01006597             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19703:6749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006597
VERSION     KCVT01006597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19703:6749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..312
                     /note="immunoglobulin light chain variable region"
     V_region        152..312
     V_segment       152..274
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84122.1"
                     /translation="CMQGLEFPITF"
     J_segment       277..312
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           69 a           89 c           85 g           72 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctctgg agtcccagac aggttcagtg
      181 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      241 gggtttatta ctgcatgcaa ggtctagagt ttccaatcac tttcggcccc gggaccaaac
      301 tggatatcaa acgag
//
LOCUS       KCVT01006598             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12664:14651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006598
VERSION     KCVT01006598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12664:14651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84123.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg aggaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006599             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18878:13431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006599
VERSION     KCVT01006599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18878:13431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84124.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaagccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006600             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20398:7834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006600
VERSION     KCVT01006600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20398:7834"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84125.1"
                     /translation="CQHSFRTPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          116 c          110 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcaatg tcacttgcag ggctagtgag
      181 agcgttagca ccaaattaca ttggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctttgctg cgtccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggaacagatt tcactctcac catcagcagc ctgcagcctg aagatgtcgc aactttttac
      361 tgtcagcata gttttcgtac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006601             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12199:7180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006601
VERSION     KCVT01006601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12199:7180"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84126.1"
                     /translation="CQQGSPFPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          112 c          108 g           96 t
ORIGIN      
        1 acatgggggc atgagcaaaa ctgacaagtc aaggcaggaa gatgttgtct ccatcacaac
       61 tcattgggtt tctgctgctc tgggttccag cctccaaggg tgaaattgtg ctgactcagt
      121 ctccagcctt tcggtctgtg actctaaagg agaaagtcac catcacctgc caggccagtc
      181 agagcattgg taatagctta cactggtacc agcagaaacc ggatcagtct ccaaagctcc
      241 tcatcaaata tgcttcccag tccatctcag gggtcccctc aaggttcagt ggcagtggat
      301 ctgggacaga tttcaccctc accatcaata gcctggaagc tgaagatgct gcgacgtatt
      361 actgtcagca gggaagtcct ttcccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006602             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13618:8886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006602
VERSION     KCVT01006602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13618:8886"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84127.1"
                     /translation="CMQALEFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           98 a          117 c          120 g          102 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccagt
      121 ctccctgccc gtcaccctta gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctacagaggc caggccagtc
      241 tccacagctc ttaatttatg aggtttccta ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttccgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006603             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20895:13578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006603
VERSION     KCVT01006603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20895:13578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84128.1"
                     /translation="CQHYNSSPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          116 c          102 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga ccgagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaatac actctcacca tcagcagtct gcagcctgaa gattttgcaa cttattactg
      361 tcaacactat aacagtagcc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006604             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20227:16352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006604
VERSION     KCVT01006604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20227:16352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84129.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006605             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10144:16787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006605
VERSION     KCVT01006605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10144:16787"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84130.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g          105 t
ORIGIN      
        1 acttgactga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006606             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10627:10024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006606
VERSION     KCVT01006606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10627:10024"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84131.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcgt
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aagatagaga tcaaacgag
//
LOCUS       KCVT01006607             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15011:9258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006607
VERSION     KCVT01006607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15011:9258"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84132.1"
                     /translation="CQQHDNAPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          116 c          113 g           84 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagagta
      181 ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcagcatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 agcagcatga caatgccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006608             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12301:6597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006608
VERSION     KCVT01006608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12301:6597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84133.1"
                     /translation="CQKYISSPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          130 c          105 g           91 t
ORIGIN      
        1 acatggggga agagctgctc agttaggacc cagagagaac catggaaatc ccagctcagc
       61 ttctcttcct cctgctactg tggctcccag gtaccaccgg acaacttata ttgactcagt
      121 ctccaaccac cctgtctctg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcagctta gcctggtacc agcagaaacc tgggcaggcc cccaggctcc
      241 tcctctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatttt gcagtatatt
      361 actgtcagaa atatattagc tccccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01006609             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22348:8038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006609
VERSION     KCVT01006609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22348:8038"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84134.1"
                     /translation="CQQYTSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          124 c          105 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtgagg
      181 acgttagcac tcatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattttgc aaaccgtttg gcaagtgggg tcccctcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga ggactttgca acttatcact
      361 gtcaacagta cactagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006610             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19231:13080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006610
VERSION     KCVT01006610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19231:13080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84135.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagtctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006611             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:17204:11845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006611
VERSION     KCVT01006611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17204:11845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84136.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          123 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc accgttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggacagtggg gatggaaaca gctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006612             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11176:8453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006612
VERSION     KCVT01006612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11176:8453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84137.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          119 c          116 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga attcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006613             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22348:19069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006613
VERSION     KCVT01006613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22348:19069"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..416
                     /note="immunoglobulin light chain variable region"
     V_region        97..416
     V_segment       97..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84138.1"
                     /translation="CQQVYSNPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          114 c          105 g          103 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtggtatc cagatgaccc agtctccatc
      121 tgccttgtct gcttctgtgg gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagttat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctacatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaggtt attactgtca
      361 acaggtttat agtaacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006614             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12537:11195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006614
VERSION     KCVT01006614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12537:11195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84139.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtggtg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006615             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7234:14677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006615
VERSION     KCVT01006615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7234:14677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..366
                     /note="immunoglobulin light chain variable region"
     V_region        43..366
     V_segment       43..329
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <306..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84140.1"
                     /translation="CMQTLEFPLTF"
     J_segment       330..366
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>369
                     /gene="IGKC"
BASE COUNT           83 a           98 c          100 g           88 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctcca ctctccctgc
       61 ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc ctcttggatg
      121 gtgaggatgg aaacacctat ttggattggt acctgcagaa gccaggccag tctccacagc
      181 tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc agtggcagtg
      241 ggtcagacac tgatttcaca ctgaaaatca ccagagtgga ggctgaggat gttggggttt
      301 attactgcat gcaaactcta gagtttcctc tcactttcgg cggagggacc aaggtggaga
      361 tcaaacgag
//
LOCUS       KCVT01006616             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18415:18449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006616
VERSION     KCVT01006616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18415:18449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84141.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          121 c          122 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccaatg gggacattgt gatgacccag
      121 actccgctct ccctgcccgt catccttgga gagccggcct ccctatcctg cacgtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01006617             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17768:12621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006617
VERSION     KCVT01006617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17768:12621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84142.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          123 c          114 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006618             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:28198:12590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006618
VERSION     KCVT01006618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:28198:12590"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84143.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctacagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006619             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10548:8447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006619
VERSION     KCVT01006619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10548:8447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84144.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          124 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006620             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:18075:7490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006620
VERSION     KCVT01006620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18075:7490"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84145.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          116 c           96 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt cagcatcact tgccggacaa gtcaagctat
      181 taccaattat ttacattggt ttcagcagaa accagggaga gcccctaagc tcctcatcta
      241 tgaaacattc agtttgacaa gtggggtccc atcaagattc agcggcagtg catctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01006621             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13821:7716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006621
VERSION     KCVT01006621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13821:7716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84146.1"
                     /translation="CLQYKSYAFSF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          111 c          104 g          103 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcttg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg taggagacac tgtcaccatc acttgccggg caagtcaggt
      181 tattatcaat tatttaaatt ggtttcagca gaaaccaggg gaagccccta agctcctgat
      241 ttatggtgca tccagtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gactttgcaa gttattactg
      361 tctacagtat aaaagttacg cattcagttt cggccccggg accagactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006622             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15176:11288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006622
VERSION     KCVT01006622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15176:11288"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84147.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg ctacttattt
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006623             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13521:16296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006623
VERSION     KCVT01006623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13521:16296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84148.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattccc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006624             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:15172:6174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006624
VERSION     KCVT01006624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15172:6174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84149.1"
                     /translation="CQQYDSDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcgtctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01006625             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16559:2322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006625
VERSION     KCVT01006625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16559:2322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84150.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt agaaatcaaa
      421 cgag
//
LOCUS       KCVT01006626             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:22564:14700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006626
VERSION     KCVT01006626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22564:14700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84151.1"
                     /translation="CLQYYSIPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          102 g          100 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatctgcag gagacagagt caccatcact tgcagggcaa gtcagggcat
      181 taggactcat ttaaattggt atcagcagaa actaggaaaa gctcctaagc gcctgatcta
      241 tgctgcatcc agtttggaga gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atttctgtct
      361 acagtattat agtatcccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006627             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19221:5720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006627
VERSION     KCVT01006627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19221:5720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84152.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006628             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23671:7750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006628
VERSION     KCVT01006628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23671:7750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84153.1"
                     /translation="CMQPLDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagattttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006629             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:26102:15353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006629
VERSION     KCVT01006629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:26102:15353"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84154.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatatgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006630             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15520:13673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006630
VERSION     KCVT01006630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15520:13673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84155.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          123 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccggactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgagtat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006631             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22678:7354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006631
VERSION     KCVT01006631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22678:7354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84156.1"
                     /translation="CQQYDSDLFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          115 c          114 g           95 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catttgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacctgtt cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01006632             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12574:21463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006632
VERSION     KCVT01006632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12574:21463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84157.1"
                     /translation="CQQYNSLPFTF"
     J_segment       378..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          104 a          119 c           97 g           98 t
ORIGIN      
        1 acatgggaga cccagccagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 aatacttatt taaattggta tcagcagaaa ccggggacag cccctaagct cctgatctat
      241 tatgcaaacc gtttgcacag tggggtccca tcaagattca gcggcagcgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcaa cctgaggatt ttgcaactta tttctgtcaa
      361 cagtataatt ctttaccatt cactttcggc cccgggacca aactggatat gaaacgag
//
LOCUS       KCVT01006633             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:23894:18245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006633
VERSION     KCVT01006633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23894:18245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84158.1"
                     /translation="CMQAREFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          126 c          117 g          102 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagat
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttc gatagtgagg aggggaacac ctatttggaa tggtacctac agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ctccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgctggg gtttattact gcatgcaagc tcgagagttt ccattcactt tcggccccgg
      421 gaccaaactg gacatcaaac gag
//
LOCUS       KCVT01006634             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17626:8822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006634
VERSION     KCVT01006634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17626:8822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84159.1"
                     /translation="CMQGLEFPPTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          124 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtggcg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtggtga tggaaacacc tatttggaat ggttcctcca gaggccaggc
      241 cagtctccac acctcttgat ttatggggct tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc ctccgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006635             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19655:2446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006635
VERSION     KCVT01006635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19655:2446"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..406
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84160.1"
                     /translation="CHQYNNLPLTF"
     J_segment       408..444
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          115 a          119 c          112 g          101 t
ORIGIN      
        1 acatggggga ggctggacag acttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctggggc tcctgctgct ctggctccca ggtgccagat
      121 gtgacattca gatgacccag tctccatcct ccctgtctgc ttctgtagga gacagagtca
      181 ccatcacttg ccgggcaagt caggacatta acatttattt aaattggtat cagcagaaac
      241 cggggaaagc ccctaagctc ctgatctatt atgcaaatcg tttggaaact ggggtcccgt
      301 caaggttcag cggcagtgga tctgggacag aattcactct caccatcaac agcctgcaac
      361 ccgaagattt tgcaacttat tactgtcacc agtataataa tttaccactc actttcggcg
      421 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006636             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19383:7147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006636
VERSION     KCVT01006636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19383:7147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84161.1"
                     /translation="CQHSFRTPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          116 c          108 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaatgtc acttgcaggg ctagtgagag
      181 cgttagcacc aaattacatt ggtatcagca gaaaccaggg aaagccccta agctcctgat
      241 ctttgctgcg tccactttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 aacagatttc actctcacca tcaacagcct gcagcctgaa gatgtcgcaa ctttttactg
      361 tcagcatagt tttcgtaccc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006637             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:23850:23139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006637
VERSION     KCVT01006637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23850:23139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84162.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgccacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006638             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20783:12042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006638
VERSION     KCVT01006638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20783:12042"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84163.1"
                     /translation="CMQALDFPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          128 c          113 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctcccccctc cctgcccgtc acccttggag aggcggcctc catctcctgt aggtctagtc
      181 agagcctctt cgatactgaa gaaggaaaca cctatttgga gtggtacctg cagaggccag
      241 gccagactcc acagctcttg atttatcagg tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg actttattac tgcatgcagg ctctagactt tccattcact ttcggccccg
      421 ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01006639             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17373:20792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006639
VERSION     KCVT01006639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17373:20792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84164.1"
                     /translation="CQQHDNSPPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagtctca gacagggcac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccttcctccc tgtctgcatc tataggcgac agagtcacca tcacttgcag agccagtcag
      181 ggtattagcg actggttggc ctggtatcaa cagaaaccag ggaaagcccc taaactcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcaggccg aagatttcgc aacatatttc
      361 tgtcaacagc atgataattc ccctcccact ttcggtggag ggactaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006640             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14167:16235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006640
VERSION     KCVT01006640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14167:16235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84165.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          122 c          120 g           94 t
ORIGIN      
        1 acacggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtatacatca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcgg ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01006641             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11703:9459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006641
VERSION     KCVT01006641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11703:9459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84166.1"
                     /translation="CQHSYGFSYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          104 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgttg gagacagact caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttgcattggt atcagcagaa accagggaaa gcccctaacc tcctgatcta
      241 tgctgcatcc actttgcaaa gtggagtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat attggaactt attactgtca
      361 gcatagttat ggtttttcgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006642             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14070:5272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006642
VERSION     KCVT01006642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14070:5272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..350
                     /note="immunoglobulin light chain variable region"
     V_region        11..350
     V_segment       11..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <290..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84167.1"
                     /translation="CMQALEFPWTF"
     J_segment       313..350
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>353
                     /gene="IGKC"
BASE COUNT           85 a           87 c          100 g           81 t
ORIGIN      
        1 acatgggggg gacattgtga tgacccagac tccactctcc ctgcccgtca cccttggaga
       61 gccggcctcc atctcctgca ggtctagtca gagtctcttg gatagtgagg atggaaacac
      121 ctatttggaa tggtacctgc agaagccagg ccagtctcca caactcttga tttatgaggt
      181 ttccaaccgg gcctctggag tcccagacag gttcagtggc agtgggtcag acactgattt
      241 cacactgaaa atcagcagag tggaggctga ggatgttggg gtttattact gcatgcaagc
      301 tctagaattt ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01006643             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21387:13474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006643
VERSION     KCVT01006643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21387:13474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84168.1"
                     /translation="CQQYNSDPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          114 c          107 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg cgagtcaggg
      181 cattagaagt tatttagcgt ggtatcagca gaaaccagga aaagccccga aggccttgat
      241 ctattacgca tccattttag agagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagtctgac gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006644             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11771:6713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006644
VERSION     KCVT01006644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11771:6713"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84169.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          119 c          106 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006645             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7837:9923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006645
VERSION     KCVT01006645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7837:9923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84170.1"
                     /translation="CQHSYTTPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          117 c          105 g          100 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gctagttata
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctatgctgc atccactttg caaagtgggg tcccatctag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatgttgcg acttattact
      361 gtcagcatag ttatactacc ccgttcactt tcggtggggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006646             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14888:16876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006646
VERSION     KCVT01006646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14888:16876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84171.1"
                     /translation="CQQYDSDSLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattccctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006647             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:6798:14425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006647
VERSION     KCVT01006647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6798:14425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84172.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgtctca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006648             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17385:7981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006648
VERSION     KCVT01006648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17385:7981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84173.1"
                     /translation="CQQGSSNPITF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          100 a          110 c          110 g           98 t
ORIGIN      
        1 acatggggga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgtccca gtctccatcc
      121 tccctgtctg cttctgtcgg agacagagtc accatcactt gccgggcaag tcagggcatt
      181 agtagttatt taaattggta tcagctgaaa ccggggaaag cccctaggct cctgatctat
      241 tatactaaca gtttgacaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagggtagta gtaatcctat cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01006649             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24690:16048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006649
VERSION     KCVT01006649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24690:16048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84174.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           98 a          125 c          114 g           84 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaca tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcgtagcctg gtaccagcag aaacctgggc aggctcccag actcctcatc
      241 tatggtgcgt ccaacagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgcag atgttgcact ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggaggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01006650             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21590:20471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006650
VERSION     KCVT01006650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21590:20471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84175.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          121 c          123 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggcaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006651             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6636:3661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006651
VERSION     KCVT01006651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6636:3661"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84176.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac tcgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01006652             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12590:10196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006652
VERSION     KCVT01006652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12590:10196"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84177.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggtacagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006653             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13078:15898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006653
VERSION     KCVT01006653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13078:15898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    175..299
                     /note="immunoglobulin light chain variable region"
     V_region        175..299
     V_segment       175..262
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <239..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84178.1"
                     /translation="CMQGLEFPPTF"
     J_segment       265..299
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>302
                     /gene="IGKC"
BASE COUNT           66 a           88 c           79 g           69 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggcga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      241 catgcaaggt ctagagtttc ctccgacgtt cggccaaggg accaaggtgg aaatcaaacg
      301 ag
//
LOCUS       KCVT01006654             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19879:13893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006654
VERSION     KCVT01006654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19879:13893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84179.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006655             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14243:18263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006655
VERSION     KCVT01006655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14243:18263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84180.1"
                     /translation="CQQGNSNPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          111 c          115 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgtcccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattag cagttattta aattggtatc agcagagacc ggggaaagcc cctaggctcc
      241 tgatctatta tgcaaacagt ttggcaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagta gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gggtaatagt aatcctctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006656             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20258:10856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006656
VERSION     KCVT01006656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20258:10856"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84181.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aatttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006657             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13285:2957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006657
VERSION     KCVT01006657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13285:2957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84182.1"
                     /translation="CQQYDSLPYSF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          110 c          108 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcgtctg taggagacac agtcaccatt acttgccggg caagtcaggg
      181 cattaacagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gcggatctgg
      301 gacagaattc actctcacca tcagtggcct gcaacctgac gattttgcaa cttattactg
      361 tcaacagtat gatagtttac catacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006658             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9744:4677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006658
VERSION     KCVT01006658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9744:4677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..396
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84183.1"
                     /translation="CLQYKSYPFTF"
     J_segment       397..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          111 a          118 c          101 g          107 t
ORIGIN      
        1 acatggggac acttcttgca ggagtcagac acagtcagga cacagcatgg acatgagggc
       61 ccccgctcat ctcctagggc tcttgctgct ctggctccca ggtgccagat gtgacatcca
      121 gatgactcag tctccatctt ccctgtctgc atctgtagga gacactgtca ccatcacttg
      181 ccgggcaagt caggttatta tcaattattt aaattggttt cagcagaaac cagggaaagc
      241 ccctaagctc ctgatttatg ctgcatccag attggaaagt ggggtcccat caaggttcag
      301 cggcagtgga tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt
      361 tgcaacttat tactgtctac agtataaaag ttacccattc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01006659             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5781:18193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006659
VERSION     KCVT01006659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5781:18193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..457
                     /note="immunoglobulin light chain variable region"
     V_region        118..457
     V_segment       118..420
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <397..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84184.1"
                     /translation="CMQALEFPLTF"
     J_segment       423..457
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>460
                     /gene="IGKC"
BASE COUNT          102 a          124 c          127 g          107 t
ORIGIN      
        1 acatgggtca acgcagagta catgggggat cacgactcct caggtcacct tctcacaatg
       61 aggctccctg ctcagctcct gggactgcta atgctctggc tccctggatc cagtggggac
      121 attgtgctga cccagactcc actctccctg cccgtcaccc ttggagagcc ggcctccatc
      181 tcctgtaggt ctagtcagag cctcttggat agtgaggatg gaaataccta tttggaatgg
      241 caccggcaga tgccaggcca gtctccacag ctcttgattt atgaggtttc caaccgggcc
      301 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      361 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct agagtttcct
      421 ctgacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006660             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11456:8507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006660
VERSION     KCVT01006660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11456:8507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84185.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagt agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006661             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:12032:10900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006661
VERSION     KCVT01006661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12032:10900"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84186.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga ttacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006662             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14929:17033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006662
VERSION     KCVT01006662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14929:17033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84187.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           94 a          116 c          121 g          108 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcactct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggtagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01006663             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12200:2770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006663
VERSION     KCVT01006663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12200:2770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84188.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggt ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006664             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18699:12092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006664
VERSION     KCVT01006664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18699:12092"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84189.1"
                     /translation="CLQGYIDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          113 c          113 g           99 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacttccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtcggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tgcaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ctgtctacag ggttatattg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006665             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10866:12825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006665
VERSION     KCVT01006665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10866:12825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84190.1"
                     /translation="CMQGLQTPYTF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          104 t
ORIGIN      
        1 acatgggggg atcaggactc ctcagttcac cttgtcacaa tgaggctccc tgctcagctc
       61 ctggggctgc taatgctctg ggtctctgcc tccagtggag atatcgtgat gacccagact
      121 ccactctcgc tgcccgtcac ccttggagag ccagcctcca tctcctgcag gtctagtcag
      181 agccttctga atagtaatgg atacagctat ttgagttggt acctgcagag gccaggccag
      241 tctccacatc tgctgatcta ttatggctct agtcgggcct ccggggtccc cgacaggttc
      301 agtggcagtg ggtcaggcac agattttaca ctgaaaatca ccagggtgga ggctgacgac
      361 gtaggggttt attactgcat gcaaggtcta caaactccgt acacttttgg ccaggggacc
      421 aaagtggaga tcaaacgag
//
LOCUS       KCVT01006666             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17585:5990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006666
VERSION     KCVT01006666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17585:5990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84191.1"
                     /translation="CQQGYSFPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           93 a          119 c          110 g          100 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagttga cgcagtctcc
      121 atcctccctg tccgcatctg taggagacac agtcgccatc acttgccagg cgagtcaggg
      181 cattgccaat aatttatatt ggtatcagca gaaaccaggg aaagccccta gactcctcat
      241 ctataggtca tccagtttgc aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc agtctcacca tcagcagcct gcagcctgaa gatttcgcct cttattactg
      361 tcaacagggt tatagtttcc cgctcacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006667             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22273:6661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006667
VERSION     KCVT01006667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22273:6661"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..376
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84192.1"
                     /translation="CQQSYRYPLTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>422
                     /gene="IGKC"
BASE COUNT          101 a          116 c          108 g           97 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgagaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagccccta aactcctgat
      241 gtatcttgca tccactttgc agagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcgcca tcagcagcct gcagcctgaa gatgctgcaa cttattactg
      361 tcagcagagt tatcgttatc cgctcacttt cggtggaggg acccaggtgg aaatcaatcg
      421 ag
//
LOCUS       KCVT01006668             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:18196:15062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006668
VERSION     KCVT01006668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18196:15062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..420
                     /note="immunoglobulin light chain variable region"
     V_region        87..420
     V_segment       87..384
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84193.1"
                     /translation="CMQGTQLLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          116 c          113 g           95 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccatga ggctccctgc tcagctcctg gggctgctat
       61 tgctctgcgt ccccggatcc agtggggatg ttgtgatgac tcagtctcca ctctccctgc
      121 ccatcacccc tggacaaccg gcctccatct cctgcaggtc tagtcaaagc cttctacaca
      181 ctgatgggaa aacctacttg aattggtatc agcagaagcc aggccaacct ccaaggcgcc
      241 taatttatca ggtttctaac cgggactctg gggtcccaga cagattcagc ggcagtgggg
      301 cagggacaga tttcacactg aaaatcagca gagtggagac tgaggatgtt ggagtttatt
      361 actgcatgca aggtacacag cttctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006669             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17082:6804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006669
VERSION     KCVT01006669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17082:6804"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..413
                     /note="immunoglobulin light chain variable region"
     V_region        94..413
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84194.1"
                     /translation="CLQFKSYPNSF"
     J_segment       380..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>418
                     /gene="IGKC"
BASE COUNT          100 a          114 c          106 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcagggtatt
      181 agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctaagct cctcatctat
      241 gctgcatcca ctttggccgg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtttaaaa gttacccgaa cagttttggc caggggacca aagtggagat caagcgag
//
LOCUS       KCVT01006670             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16819:5111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006670
VERSION     KCVT01006670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16819:5111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84195.1"
                     /translation="CQQDFDWPPTF"
     J_segment       390..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          126 c          113 g           88 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc tccagcacag
       61 cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcaacacctt aacctggtac cagcacaaac ctgggcaggc tcccaagctc
      241 ctcctctatg gtgcatccac cagggcctcc ggcatcccag gcaggttcag tgccagtggg
      301 tctggaacag agtttactct caccatcagc agcctggagc ctgaagatgt tggaatttat
      361 tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01006671             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8878:18265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006671
VERSION     KCVT01006671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8878:18265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..337
                     /note="immunoglobulin light chain variable region"
     V_region        16..337
     V_segment       16..285
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <277..>309
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84196.1"
                     /translation="CLQGYTIPYTF"
     J_segment       300..337
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        338..>340
                     /gene="IGKC"
BASE COUNT           92 a           86 c           83 g           79 t
ORIGIN      
        1 acatgggcca gatgtgacat ccagatgacc cagtctccat cttccctgtc tgcatcggta
       61 ggagacagag tcaccatcac ttgccggaca agtcagggca ttagcgatta tttaagttgg
      121 tatcagcaga aaccaggaaa agctcctaag cgcctgatcc atgctgtatc cagtttggaa
      181 agtggggccc catcaaggtt cagcggcagt ggatctgaaa cagagttcac tctcaccatc
      241 agcagcctgc agcctgaaga ttttgcaact tattactgtc tacagggtta tactatcccg
      301 tacacttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01006672             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9975:14823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006672
VERSION     KCVT01006672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9975:14823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84197.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgacacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006673             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10486:14652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006673
VERSION     KCVT01006673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10486:14652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84198.1"
                     /translation="CLQYKNFPLSF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          112 c          107 g          103 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatgggc atgagggccc ccgctcatct
       61 cctagggctc ttgctgctct ggctcccagg tgccaggtgt gacatccaga tgactcagtc
      121 tccgtcttcc ctgtctgcat ctctaggaga cactgtcacc atcacttgcc gggcaagtca
      181 ggatattaac agttatttaa attggtttca gcagaaacca gggaaagccc ctaagctcct
      241 gatctatggt gcatccagtt tggaaagtga ggtcccatta agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttattt
      361 ctgtctacag tataaaaatt tcccgctctc tttcggcgga gggaccaggg tggacatcaa
      421 acgag
//
LOCUS       KCVT01006674             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16850:10883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006674
VERSION     KCVT01006674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16850:10883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84199.1"
                     /translation="CQQYDSDPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag cttggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattagcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctatttcgca tccactttgg aaagtggcgt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006675             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18351:7589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006675
VERSION     KCVT01006675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18351:7589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..319
                     /note="immunoglobulin light chain variable region"
     V_region        120..319
     V_segment       120..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <259..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84200.1"
                     /translation="CVQALEFPWTF"
     J_segment       282..319
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>322
                     /gene="IGKC"
BASE COUNT           72 a           82 c           89 g           79 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      181 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      241 gatgttgggg tttattactg cgttcaagct ctagagtttc cgtggacttt cggccaaggg
      301 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006676             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12426:15884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006676
VERSION     KCVT01006676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12426:15884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84201.1"
                     /translation="CQQHDNAPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          116 c          115 g           85 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 agtattaacg actggttggc ctggtatcaa cagagaccag ggaaggcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcag catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcagcagc atgacaatgc cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006677             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10881:20187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006677
VERSION     KCVT01006677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10881:20187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84202.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           94 a          120 c          117 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 attctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc caggcaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg agactgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01006678             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18890:13160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006678
VERSION     KCVT01006678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18890:13160"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84203.1"
                     /translation="CQQHNGYPATF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          118 c          109 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctgcgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006679             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19859:16354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006679
VERSION     KCVT01006679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19859:16354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84204.1"
                     /translation="CLQSKNSPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g          100 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcgtc tgcagagcca gtgagagtgt
      181 caatgtcttt ggaataaacc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 acccctgatt taccaagcat ccaataaaga aactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgacg atgctgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggacgttt ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01006680             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8780:13491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006680
VERSION     KCVT01006680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8780:13491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84205.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactact aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006681             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16255:11122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006681
VERSION     KCVT01006681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16255:11122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84206.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>428
                     /gene="IGKC"
BASE COUNT           99 a          126 c          118 g           85 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatag tgctgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaaa cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta
      361 ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaccgag
//
LOCUS       KCVT01006682             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25538:13394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006682
VERSION     KCVT01006682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25538:13394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84207.1"
                     /translation="CLQGYSAPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          107 g           97 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcttc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gaaaaactcc tcagcgcctg
      241 atctatgctg catccagttt ggagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggcacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctacagg gttatagtgc cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 agag
//
LOCUS       KCVT01006683             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20372:19911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006683
VERSION     KCVT01006683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20372:19911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84208.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgtgt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006684             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:1853:13113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006684
VERSION     KCVT01006684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:1853:13113"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84209.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagtc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006685             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:13893:8971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006685
VERSION     KCVT01006685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13893:8971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84210.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca tagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006686             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21670:3235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006686
VERSION     KCVT01006686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21670:3235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84211.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtactg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat tttctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006687             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22819:8317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006687
VERSION     KCVT01006687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22819:8317"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..371
                     /note="immunoglobulin light chain variable region"
     V_region        91..371
     V_segment       91..331
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84212.1"
                     /translation="CQTFKSYLSVPF"
     J_segment       339..371
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>374
                     /gene="IGKC"
BASE COUNT          101 a           89 c           95 g           89 t
ORIGIN      
        1 acatgggggt agaagtcaga accactcagg acacaggatg gacatgacgg tccccgctta
       61 tctcctgggg ctccttctgc tctggctccc aggagacaaa gtcaccatca cttgcagggc
      121 aagtcaggac attggtaatt atttaaattg gtatcagcag aaaccaggaa aagctcctaa
      181 ggtcctgatc tatggtgtat ccaatttaca aagtggggtc ccatcaaggt tcagcggcag
      241 tggatctggg acagatctta ctctcaccat cagcagcctg cagcctgaag attttgcaac
      301 gtattattgt caaacgttta aaagttacct ttcggtccct ttcggcggag ggaccaaggt
      361 ggagatcaaa cgag
//
LOCUS       KCVT01006688             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5445:20173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006688
VERSION     KCVT01006688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5445:20173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84213.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c          103 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccggtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgaa gactttgcaa cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006689             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:29246:14637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006689
VERSION     KCVT01006689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:29246:14637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84214.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006690             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16720:20095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006690
VERSION     KCVT01006690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16720:20095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84215.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc actggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttatttct
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006691             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18082:17510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006691
VERSION     KCVT01006691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18082:17510"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84216.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          115 c          110 g           89 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 gatattaaca actggttggt ctggtatcaa cagaaaccag ggaaagcccc taaggtcctg
      241 atctataggg catccatttt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006692             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17031:11409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006692
VERSION     KCVT01006692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17031:11409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84217.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg agacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaata cctatttgga atggcaccgg cagatgccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctgacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006693             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12617:15360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006693
VERSION     KCVT01006693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12617:15360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..418
                     /note="immunoglobulin light chain variable region"
     V_region        104..418
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84218.1"
                     /translation="CQQYNTLPLTF"
     J_segment       388..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>428
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           95 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacactc agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt aacatttatt taaattggta tcagcagaaa ccggggaaag cccctgagct
      241 cctgatctat tatgcaaacc gtttggaaac tggggtccca tcaaggttca gcggcggtgg
      301 atctgggaca gaattcagtc tcaccatcag cagcctgcaa cctgaggact ttgcaactta
      361 ttactgtcaa cagtataata ctttaccgct cactttcggc ggagggacca aggtggaggt
      421 cagacgag
//
LOCUS       KCVT01006694             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9825:4105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006694
VERSION     KCVT01006694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9825:4105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84219.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtatcag cagcagcgta gcctggtacc agcaaaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006695             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13206:20894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006695
VERSION     KCVT01006695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13206:20894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..246
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84220.1"
                     /translation="CQQNSNWPLTF"
     J_segment       247..283
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           71 a           78 c           80 g           57 t
ORIGIN      
        1 acatggggag aaagagccac cctctcctgc agggccagtc agagtgtcag cagcagctta
       61 gcctggtacc aacaaaaacc tgggcaggct cccaggctcc tcatctatgg tgcatccagc
      121 agggccactg gcatcccaga caggttcagt ggcagtgggt ctgggacaga cttcactctc
      181 accatcacca gcctggagcc tgaagatgtt gcagtttatt attgtcagca gaatagtaac
      241 tggcctctca ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01006696             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8728:7542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006696
VERSION     KCVT01006696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8728:7542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84221.1"
                     /translation="CQQSYDTPYTF"
     J_segment       384..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          119 c          105 g           95 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtccga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct gagctcctga
      241 tctatgctgc atccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gggcagattt cactctcacc atcagcagcc tgcagcctga agatgttgca acttatttct
      361 gtcagcaaag ttatgatacc ccctacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006697             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:12499:14243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006697
VERSION     KCVT01006697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12499:14243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84222.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01006698             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:23113:13968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006698
VERSION     KCVT01006698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23113:13968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84223.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          111 c          110 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctaatcta
      241 tgctgcatct agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagttt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga ttaaacgag
//
LOCUS       KCVT01006699             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13943:16501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006699
VERSION     KCVT01006699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13943:16501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84224.1"
                     /translation="CQQNSNWPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           98 a          125 c          119 g           86 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggctccc agataccacc ggagaaatgg tgctgacgca
      121 gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag
      181 tcagagtgtc agcagcagct tagcctggta ccagcagaca cctgggcagg ctcccagact
      241 cctcatctat ggtgcatcca acagggccac tggcatccca ggcaggttca gtggcagtgg
      301 gtctgggaca gagttcactc tcaccatcag cagcctggag tctgaagatg ttgcacttta
      361 ttattgtcag cagaacagta actggcctct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01006700             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13936:11184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006700
VERSION     KCVT01006700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13936:11184"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84225.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gacattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattacg catccaattt ggagagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006701             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16285:10879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006701
VERSION     KCVT01006701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16285:10879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84226.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          126 c          112 g           88 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccag cacaaacctg ggcaggctcc caagctcctc
      241 ctctatggtg catccaccag ggcctccggc atcccaggca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006702             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8669:15181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006702
VERSION     KCVT01006702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8669:15181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84227.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggttccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006703             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24809:7745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006703
VERSION     KCVT01006703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24809:7745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84228.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tacatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt ggactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006704             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5359:18348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006704
VERSION     KCVT01006704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5359:18348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84229.1"
                     /translation="CMQALDFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          122 c          122 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atgcagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctgc
      361 ggatgttggg gtttattact gcatgcaagc tctagacttt cccctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01006705             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10246:21399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006705
VERSION     KCVT01006705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10246:21399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84230.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcaaagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01006706             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13388:9123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006706
VERSION     KCVT01006706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13388:9123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    167..333
                     /note="immunoglobulin light chain variable region"
     V_region        167..333
     V_segment       167..295
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <273..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84231.1"
                     /translation="CMQALEFPYSF"
     J_segment       297..333
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        334..>336
                     /gene="IGKC"
BASE COUNT           71 a           96 c           93 g           76 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagc cgggcctctg
      181 gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca
      241 gagtggaggc tgaggatgtt ggggtttatt actgcatgca agctctagag tttccctaca
      301 gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01006707             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12791:3632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006707
VERSION     KCVT01006707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12791:3632"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..424
                     /note="immunoglobulin light chain variable region"
     V_region        93..424
     V_segment       93..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84232.1"
                     /translation="CGQGTYLLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT           91 a          118 c          121 g           97 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccga gtccagtggg ggtgttgtta tgactcagtt tccgctctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgtg
      181 cacaccaatg gatacacata cttgagttgg tatcaccaga ggccaggcca acctccaagg
      241 cgcctcattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      361 tattactgcg ggcaaggtac ataccttctc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006708             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:3036:17711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006708
VERSION     KCVT01006708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3036:17711"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84233.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          127 c          122 g           86 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagacatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcgtccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgcagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggag gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01006709             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:26230:15974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006709
VERSION     KCVT01006709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:26230:15974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84234.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006710             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14395:10053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006710
VERSION     KCVT01006710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14395:10053"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84235.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006711             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13129:11556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006711
VERSION     KCVT01006711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13129:11556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..380
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84236.1"
                     /translation="CQQDYSYPLTF"
     J_segment       381..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>420
                     /gene="IGKC"
BASE COUNT           97 a          115 c          115 g           93 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacatgag ggtccccgtg cagctcctgg
       61 ggctcctgtt gctctggctc caaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccgtcac ttgccgggcg agtcaaggca
      181 ttaacgggga cttaagctgg tatcagcaga aaccagggaa agcccctaca ctcctgatct
      241 atgctgcctc cagtttgcag acgggggtct catctcggtt cagtggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 aacaggatta tagttacccg ctcactttcg gtggagggac caaggtggaa atcagacgag
//
LOCUS       KCVT01006712             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7643:9569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006712
VERSION     KCVT01006712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7643:9569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84237.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          118 c          110 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaagacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006713             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:8083:11497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006713
VERSION     KCVT01006713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8083:11497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84238.1"
                     /translation="CQQYNRFPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          111 c          106 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggc
      181 cattagtaat tacttaaatt ggtatcagca aaagccgggg aaagccccaa agcccctgat
      241 ctattatgta aaccgtttgg aaaatggagt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa tttattactg
      361 tcaacaatat aataggtttc ctctcacttt cggtgggggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006714             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15733:4709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006714
VERSION     KCVT01006714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15733:4709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84239.1"
                     /translation="CMQALEFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctcatg ctctggctcc ctgtatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatgtcc tgcaggtcta gtcagagtct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcggtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgatgatgt
      361 tggggtttat tactgcatgc aagctctaga gtttccgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006715             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22621:5143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006715
VERSION     KCVT01006715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22621:5143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..355
                     /note="immunoglobulin light chain variable region"
     V_region        149..355
     V_segment       149..318
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <295..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84240.1"
                     /translation="CMQALEFPWTF"
     J_segment       319..355
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>358
                     /gene="IGKC"
BASE COUNT           80 a           98 c           96 g           84 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt ctagtcagag ccaggccagt ctccacacct cttgatttat
      181 gaagtttcca accgggcctc tggagtccca gacaggttca gtggcagtgg gtcagacact
      241 gatttcacac tgaaaatcag cagagtggag gctgaggatg ttggggttta ttactgcatg
      301 caagctctag agtttccttg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01006716             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13338:11586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006716
VERSION     KCVT01006716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13338:11586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84241.1"
                     /translation="CQQYDKSPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          117 g           86 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagggtcacc atcacttgca gagccagtca
      181 gggtatcagc aactggttgg cctggtatca acagaaacca gggagagccc ctaacctcct
      241 gatgtatagg gcgtccaatt tgcaaggagg ggtcccatca aggttcagag gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaggatgtcg ctacatatta
      361 ctgtcaacag tatgataagt cccctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006717             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22674:16929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006717
VERSION     KCVT01006717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22674:16929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84242.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacctt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01006718             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10342:20600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006718
VERSION     KCVT01006718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10342:20600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84243.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gtagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatta
      361 ctgtcaacag tatgacagtg acccgttcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01006719             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19430:9937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006719
VERSION     KCVT01006719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19430:9937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84244.1"
                     /translation="CQQYKSLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          106 c          111 g           97 t
ORIGIN      
        1 acatgggagg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgtat ctgtaggaga cagagtcacc atcatttgcc gggcaagtga
      181 ggacattagc agttatttaa attggtatca gcagaaaccg gggaaagccc ctaaggtcct
      241 gatgtattat tcaaaccgtt tggagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctaa ccatcagcag cctgcaatct gaggattttg caacttatca
      361 ctgtcaacag tataaaagct taccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006720             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11549:3135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006720
VERSION     KCVT01006720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11549:3135"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84245.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          118 g           86 t
ORIGIN      
        1 acatgggggg ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatctaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006721             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:5118:12857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006721
VERSION     KCVT01006721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5118:12857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84246.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatggtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcggtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagacttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01006722             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11348:6623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006722
VERSION     KCVT01006722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11348:6623"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84247.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          118 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacactta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006723             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22219:10663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006723
VERSION     KCVT01006723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22219:10663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84248.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtgacag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006724             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14313:3979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006724
VERSION     KCVT01006724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14313:3979"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..265
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <249..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84249.1"
                     /translation="CMQSLDLPFTF"
     J_segment       272..309
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>312
                     /gene="IGKC"
BASE COUNT           72 a           81 c           85 g           74 t
ORIGIN      
        1 acatgggcac ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcgtgg
       61 atagtgagga tggaaacacc tatttggaat ggttcctgca gaggccaggc cagtctccac
      121 agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg ttcagtggca
      181 gtgggtcaga cactgatttc acactgcaaa tcagcagagt ggaggctgag gatgttgggg
      241 tttattactg catgcaatct ctagaccttc cattcacttt cggccccggg accaaactgg
      301 atatcaaacg ag
//
LOCUS       KCVT01006725             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:6358:9562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006725
VERSION     KCVT01006725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6358:9562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84250.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           86 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006726             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18519:11411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006726
VERSION     KCVT01006726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18519:11411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..297
                     /note="immunoglobulin light chain variable region"
     V_region        87..297
     V_segment       87..245
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84251.1"
                     /translation="CLQQFNNPLTF"
     J_segment       260..297
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>300
                     /gene="IGKC"
BASE COUNT           76 a           82 c           78 g           64 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccaga aaccaggaaa agctcctaag cgcctgatct
      121 atgctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      181 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact aattgctgtc
      241 tacagcaatt taataacccg ctcactttcg ctggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01006727             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17377:20749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006727
VERSION     KCVT01006727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17377:20749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84252.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt actaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006728             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15800:14651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006728
VERSION     KCVT01006728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15800:14651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84253.1"
                     /translation="CQQGHSYPWTF"
     J_segment       379..408
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          109 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc atctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccagtcga gtctaggcat
      181 tggcaaattt ttaaattggt atcagcagaa accagggaaa gcccccaaac tcctgatcta
      241 tagggcatcc agtttgcaaa ctgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccgctt attactgtca
      361 acagggtcat agttacccgt ggacgttcgg ccaagggacc aaggtggaga tgaaacgag
//
LOCUS       KCVT01006729             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25634:8044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006729
VERSION     KCVT01006729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25634:8044"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84254.1"
                     /translation="CQQGYSYPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          120 c          106 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gatgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca ggcgagtcac
      181 ggcattggca ataatttaaa ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atctatacgg catccaggtt acaaggtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcggc ctgcagcctg aagatcttgc cacttattac
      361 tgtcaacagg gttatagtta cccattcact ttcggtcccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006730             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19698:19346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006730
VERSION     KCVT01006730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19698:19346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84255.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cggcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006731             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19774:10951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006731
VERSION     KCVT01006731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19774:10951"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..371
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84256.1"
                     /translation="CQQYDSDPFTF"
     J_segment       374..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT          100 a          112 c          108 g           92 t
ORIGIN      
        1 acatgggagt caggacacag catggacatg agggtccccg ctcagctcct aggactcctg
       61 ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc atcctccctg
      121 tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg cattcgcagt
      181 tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat ctattacgcg
      241 tccagtttgg aaagtggggt cccatcaagg ttcagcggcg gtggatctgg gacagaattc
      301 actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagtat
      361 gacagtgacc cgttcacttt cggtggaggg accaaggtag acatcaaacg ag
//
LOCUS       KCVT01006732             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11619:20033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006732
VERSION     KCVT01006732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11619:20033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <252..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84257.1"
                     /translation="CQHSHGSPITF"
     J_segment       277..312
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>315
                     /gene="IGKC"
BASE COUNT           82 a           80 c           77 g           76 t
ORIGIN      
        1 acatggggtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca
       61 gggcaagtga gaacgtttac aactatttac attggtatca gcagaaacca gggaaagccc
      121 ctaaggtcct gatctatgct gcatccactt tgcaaagtgg agtcccatca aggttcagcg
      181 gcagtggatc tgggactgat ttcactctca ccatcagcag cctgcagcct gaagatgttg
      241 caacttatta ctgtcagcat agtcatggat cccctatcac tttcggtgga gggaccaagg
      301 tggagatcaa acgag
//
LOCUS       KCVT01006733             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8391:16366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006733
VERSION     KCVT01006733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8391:16366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..448
                     /note="immunoglobulin light chain variable region"
     V_region        109..448
     V_segment       109..410
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <388..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84258.1"
                     /translation="CMQPLEFPWTF"
     J_segment       411..448
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>451
                     /gene="IGKC"
BASE COUNT           99 a          121 c          124 g          107 t
ORIGIN      
        1 acatgggggg ccttgactga tcacgactcc tcaggtcacc ttctcacaat gaggctccct
       61 gctcagctcc tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg
      121 acccagattc cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg
      181 tctagtcaga gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag
      241 aagccaggcc agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc
      301 ccagacaggt tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg
      361 gaggctgagg atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc
      421 ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006734             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12376:19156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006734
VERSION     KCVT01006734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12376:19156"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84259.1"
                     /translation="CQHGYGIQLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           99 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcccagtca ggacacagca tggacatgag ggcccccact cagctcctgg
       61 ggttcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgtg ggagacagag tcaccatctc ttgccaggcg agtcaggaca
      181 ttagcaatga tttagcctgg tatcagcaga aaccgggaaa agcccctagg ctcctgatgt
      241 ataaggcatc cgctttgcag attggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc aacagcctgc agcctgaaga ttttgcaact tactactgtc
      361 aacatggtta tggtatccag ctcactttcg gtggagggac caaggtggac atcaaacgag
//
LOCUS       KCVT01006735             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11859:18463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006735
VERSION     KCVT01006735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11859:18463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..375
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84260.1"
                     /translation="CQQGYTYPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          122 c          105 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgctcc tgtaggagac acagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca gaaatttaaa ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 ctctataggg catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatactta ccctttcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006736             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16647:15357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006736
VERSION     KCVT01006736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16647:15357"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84261.1"
                     /translation="CMQALDFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           96 a          123 c          122 g          105 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatgcagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgcggatgtt ggggtttatt actgcatgca agctctagac tttcccctca ctttcggcgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01006737             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22132:17006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006737
VERSION     KCVT01006737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22132:17006"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84262.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006738             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16225:5734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006738
VERSION     KCVT01006738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16225:5734"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    71..392
                     /note="immunoglobulin light chain variable region"
     V_region        71..392
     V_segment       71..354
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84263.1"
                     /translation="CQQYNSLPYSF"
     J_segment       355..392
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>395
                     /gene="IGKC"
BASE COUNT           96 a          101 c          102 g           96 t
ORIGIN      
        1 acatggggac atgagggtcc ccgctcagct cctggggctc ctgctgctct ggctcccagg
       61 tgccagatgt gacattgaga tgacccagtc tccatcctcc ctgtctgctt ctgtaggaga
      121 cagagtcacc atcacttgcc gggcaagtca gggcgttaac gtttatttaa attggtatca
      181 gcagaaaccg gggaaagccc ctaagcccct gatcttttat gcaaaccgtt tggaacgtgg
      241 ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag
      301 cctgcaacct gaagattttg caagttatta ttgtcaacag tataatagtt taccgtacag
      361 ttttggccag gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01006739             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14192:13253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006739
VERSION     KCVT01006739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14192:13253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..363
                     /gene="IGKV1-61"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84264.1"
                     /translation="CQQGQTYPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          118 c          108 g           93 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcacg tgccaggcga gtcaaggcat
      181 tgacaataat ttaaattggt atcaactgaa accagggaaa gcccctaaac tcctgatcga
      241 cagggcatcc agtttgcaaa gtgggattcc ctctcggttc agtggcagag gatctgggac
      301 ggatttcgct ctcaccatca ccagcctgca gcctgaggat tttgccactt atttttgtca
      361 acaaggtcag acttacccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006740             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11129:13530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006740
VERSION     KCVT01006740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11129:13530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84265.1"
                     /translation="CQHSYTTPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gctagttata
      181 acgttaacaa ctatttacat tggtatcaac agaaaccagg gaaagcccca aacctcctga
      241 tctatgttgc atccactttg caaagtgggg tcccatccag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatgttgcg acttattact
      361 gtcagcatag ttatactacc ccgttcactt tcgggggggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006741             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21718:11236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006741
VERSION     KCVT01006741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21718:11236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84266.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01006742             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13385:14537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006742
VERSION     KCVT01006742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13385:14537"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84267.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01006743             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7761:8859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006743
VERSION     KCVT01006743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7761:8859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84268.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006744             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17002:11405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006744
VERSION     KCVT01006744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17002:11405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84269.1"
                     /translation="CQQYNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          118 c          108 g           93 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataataat tattctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006745             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18402:4077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006745
VERSION     KCVT01006745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18402:4077"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84270.1"
                     /translation="CQQGYTYPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          121 c          103 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gctcctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcagaaat ttaaattggt atcagcagaa accagggaaa gcccctaaac tcctgctcta
      241 tagggcatcc agtttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttaccctt tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006746             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:24837:21560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006746
VERSION     KCVT01006746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24837:21560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84271.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactact aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006747             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:23853:3835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006747
VERSION     KCVT01006747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23853:3835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84272.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 atggggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006748             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:13994:14065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006748
VERSION     KCVT01006748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13994:14065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84273.1"
                     /translation="CQQYNSLPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          103 g          100 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgttggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattggca gttttttaga ttggtatcag cagaaaccgg ggaaagcccc taacctcctg
      241 atctattatt caaaccgttt ggaaaatggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aggattttgc aacttattac
      361 tgtcaacagt ataatagttt acccttcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006749             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16883:5548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006749
VERSION     KCVT01006749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16883:5548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84274.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ttccagccac cctgtctttg tctccaagag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc aacagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccgctg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagacgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006750             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9493:11549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006750
VERSION     KCVT01006750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9493:11549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..321
                     /note="immunoglobulin light chain variable region"
     V_region        122..321
     V_segment       122..283
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <261..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84275.1"
                     /translation="CMQPLEFPWTF"
     J_segment       284..321
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>324
                     /gene="IGKC"
BASE COUNT           74 a           86 c           87 g           77 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtga tgacccagac
      121 tccactctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      181 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      241 aggatattgg ggtttattac tgcatgcaac ctctagagtt tccgtggacg ttcggccaag
      301 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006751             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:24895:8358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006751
VERSION     KCVT01006751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24895:8358"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84276.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattctg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgaa gatggaaaca cctatttgca ctggtacctg aagaagccag
      241 gccagtctcc acagctctta atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006752             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20415:9530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006752
VERSION     KCVT01006752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20415:9530"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84277.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gattaaacga g
//
LOCUS       KCVT01006753             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19256:14797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006753
VERSION     KCVT01006753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19256:14797"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..359
                     /note="immunoglobulin light chain variable region"
     V_region        82..359
     V_segment       82..322
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84278.1"
                     /translation="CQQHDDSPRTF"
     J_segment       324..359
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           99 a           98 c           94 g           71 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggagacag agtcaccatc acttgcacag ccagccacga
      121 tataaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta agctcctgat
      181 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcagtggaa gtggatctgg
      241 gacagatttc actctcagca tcagcagcct gcagcctgaa gatttcgcaa catattactg
      301 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      361 ag
//
LOCUS       KCVT01006754             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:20985:13448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006754
VERSION     KCVT01006754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20985:13448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84279.1"
                     /translation="CQQHDNAPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          115 c          113 g           84 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagagtat
      181 taacgactgg ttggcctggt atcaacagag accagggaag gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcagcatca gcagcctgca gcctgaagat atcgcaacat attactgtca
      361 gcagcatgac aatgccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006755             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20472:18080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006755
VERSION     KCVT01006755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20472:18080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84280.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01006756             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20227:17796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006756
VERSION     KCVT01006756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20227:17796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84281.1"
                     /translation="CQQYDSDPFTF"
     J_segment       383..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attcgcagtt atttagcgtg gtatcaacag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgaccc gttcactttc ggtggaggga ccaaggtaga gatcaaacga
      421 g
//
LOCUS       KCVT01006757             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13882:18220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006757
VERSION     KCVT01006757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13882:18220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84282.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          110 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg gacaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006758             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:25903:14995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006758
VERSION     KCVT01006758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25903:14995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84283.1"
                     /translation="CMQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatgttgag gatggaaaca cctatttgga ctggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gttttatttc tgcatgcaga gtctggagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006759             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:5033:14671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006759
VERSION     KCVT01006759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5033:14671"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84284.1"
                     /translation="CQHGYGIPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag tcccagtcag gacacagcat ggacatgagg gcccccactc agctcctggg
       61 gttcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc aatctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccaggcga gtcaggccat
      181 tagtaataat ttagtctggt atcagcagca accggggaaa gcccctaagc tcctgatcta
      241 taaggcatcc actttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 gcatggttat ggtatcccgt ggacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006760             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:12640:10889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006760
VERSION     KCVT01006760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12640:10889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84285.1"
                     /translation="CMQALEFPWTF"
     J_segment       406..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          101 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttag agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tacagaggcc
      241 aggccagtct ccacagctct taatttatga ggtttcctac cgggcctctg gagtcccaga
      301 gaggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagaa tttccgtgga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01006761             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:25556:11300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006761
VERSION     KCVT01006761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25556:11300"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84286.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>442
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatcaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcagacg ag
//
LOCUS       KCVT01006762             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18961:18947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006762
VERSION     KCVT01006762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18961:18947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84287.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          113 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006763             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14696:12073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006763
VERSION     KCVT01006763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14696:12073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..367
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84288.1"
                     /translation="CQQHNGYPPTF"
     J_segment       380..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          106 a          118 c          104 g           89 t
ORIGIN      
        1 acatggggaa ccactcagga cacagcatgg acatgagggt ccccgctcag ctcctggggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct
      121 ccctgtctgc atctgtagga gacacagtca ccatcacttg tcgggcaagt cagggcatta
      181 cgaatgattt agcctggtat caacagaaac caggtaaagc cccgaagccc ctgatctatt
      241 acgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 atttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tattgtcaac
      361 agcataatgg ataccctccg acgttcggcc aagggaccag ggtggaaatc aaacgag
//
LOCUS       KCVT01006764             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10292:11926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006764
VERSION     KCVT01006764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10292:11926"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84289.1"
                     /translation="CQQYNSDPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          117 c          100 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt aaccatcact tgtcgggcga gtcaggacat
      181 aagaagttat ttagcgtggt atcagcagaa accaggcaaa cccccgaagc ccttgatcta
      241 ttacgcatcc gttttggaaa gtggggtccc atcaaggttc agtggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagtctgca gcctgaggat tttgcaactt attactgtca
      361 acaatataac agtgacccat tcactttcgg ccccgggacc aaactggata ccaaacgag
//
LOCUS       KCVT01006765             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16381:17483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006765
VERSION     KCVT01006765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16381:17483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84290.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          121 c          109 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacagccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccacgg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006766             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8470:11200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006766
VERSION     KCVT01006766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8470:11200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84291.1"
                     /translation="CMQAREFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           96 a          118 c          125 g          107 t
ORIGIN      
        1 acatgggggg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccagtc tccctgcccg tcactcttgg agagccggcc tccatctcct gcatgtctag
      181 tcagagcctc ttggatagtg aggatggaaa cacctatgtg gaatggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttcctac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctcgagag tttcctctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01006767             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19136:13192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006767
VERSION     KCVT01006767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19136:13192"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84292.1"
                     /translation="CQHSFRTPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          116 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaatgt cacttgcagg gctagtgaga
      181 gcgttagcac caaattacat tggtatcagc agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc gtccactttg caaagtgggg tcccagcaag gttcagcggc agtggatctg
      301 gaacagattt cactctcacc atcagcagcc tgcagcctga agatgtcgca actttttact
      361 gtcagcatag ttttcgtacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006768             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:20660:6137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006768
VERSION     KCVT01006768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20660:6137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84293.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcaattat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006769             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24920:10141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006769
VERSION     KCVT01006769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24920:10141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84294.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          118 g          108 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaagat ggaaacacct atttggagtg gtatctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01006770             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12216:12054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006770
VERSION     KCVT01006770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12216:12054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84295.1"
                     /translation="CQQDFDWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          128 c          117 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaagttgt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcaacacctt aacctggtac caccacaaac gtgggcaggc
      241 tcccaagctc ctcctctatg gtgcatccac cagggccacc ggcatcccag acaggttcag
      301 tgccagtggg tctggaacag agtttacact caccatcagc agcctggagc ctgaagatgt
      361 tggaatttat tactgtcagc aggattttga ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006771             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8563:13872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006771
VERSION     KCVT01006771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8563:13872"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..297
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84296.1"
                     /translation="CQQHNNYSPTF"
     J_segment       310..344
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           90 a           95 c           83 g           79 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccaccct ccctgtctgc
       61 atctgtagga gacacagtca ccatcacttg tcgggcaagt cagggcatta gcaatgattt
      121 agtctggtat cagctgaaac cagggaaagc cccgaagccc ctgatctatt acgcatccaa
      181 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agcataataa
      301 ttactctccc actttcggcg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01006772             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12354:17915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006772
VERSION     KCVT01006772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12354:17915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84297.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccatcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006773             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10274:4695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006773
VERSION     KCVT01006773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10274:4695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84298.1"
                     /translation="CQQYNSLPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          108 c          110 g           98 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcttcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc agttttttaa attggtatca gcagaaaccg gggaaagccc ctaaggccct
      241 gatctattat gcaaaccggt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaatct gaagattttg caacttatta
      361 ctgtcaacag tataatagtt taccgtacag ttttggccag gggaccaaag tagagatcaa
      421 acgag
//
LOCUS       KCVT01006774             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10102:7799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006774
VERSION     KCVT01006774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10102:7799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84299.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcggagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006775             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7329:9855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006775
VERSION     KCVT01006775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7329:9855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..369
                     /note="immunoglobulin light chain variable region"
     V_region        185..369
     V_segment       185..331
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <309..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84300.1"
                     /translation="CMQALEFPWTF"
     J_segment       332..369
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>372
                     /gene="IGKC"
BASE COUNT           78 a          104 c          105 g           85 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca
      241 gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag gatcttgggg
      301 tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg accaaggtgg
      361 aaatcaaacg ag
//
LOCUS       KCVT01006776             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:11200:21305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006776
VERSION     KCVT01006776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11200:21305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84301.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006777             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:23141:10354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006777
VERSION     KCVT01006777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23141:10354"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84302.1"
                     /translation="CQQYNSLPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          109 c          111 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgta ggttattact
      361 gtcaacagta taatagttta ccgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006778             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:16950:19390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006778
VERSION     KCVT01006778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16950:19390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84303.1"
                     /translation="CMQALEFPLTF"
     J_segment       397..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          103 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagaacct
      181 cctggatagt gaggatggaa acacctattt gctctggtac ctgaagaagc caggccagtc
      241 tccacagctc ttaatttatg aagtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttccgctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01006779             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16435:7227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006779
VERSION     KCVT01006779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16435:7227"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84304.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006780             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12656:9390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006780
VERSION     KCVT01006780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12656:9390"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84305.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccgtcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01006781             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14287:18975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006781
VERSION     KCVT01006781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14287:18975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84306.1"
                     /translation="CHQYNNLPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          114 c          105 g           97 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaac atttatttaa attggtatca gcagaaaccg gggaaagccc ctaagctcct
      241 gatctattat gcaaatcgtt tggaaactgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcaacag cctgcaaccc gaagattttg caacttatta
      361 ctgtcaccag tataataatt taccactcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006782             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24371:12477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006782
VERSION     KCVT01006782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24371:12477"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84307.1"
                     /translation="CQQSYRYPLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          100 a          117 c          110 g           98 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccaggtgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaac aactatttac attggtatca gcagaagcca gggaaagccc ctaaactcct
      241 gatgtttctt acatccactt tgcagagtgg cgtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctcg ccatcagcag cctgcagcct gaagatgctg caacttatta
      361 ctgtcagcag agttatcgtt atccgctcac tttcggtgga gggacccagg tggaaatcaa
      421 tcgag
//
LOCUS       KCVT01006783             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7497:17111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006783
VERSION     KCVT01006783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7497:17111"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84308.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          121 c          117 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagaa
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacctgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actaaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006784             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19736:14145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006784
VERSION     KCVT01006784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19736:14145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    141..462
                     /note="immunoglobulin light chain variable region"
     V_region        141..462
     V_segment       141..424
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <402..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84309.1"
                     /translation="CLQYKGYPYSF"
     J_segment       425..462
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        463..>465
                     /gene="IGKC"
BASE COUNT          108 a          126 c          118 g          113 t
ORIGIN      
        1 acatgggggc cttgaagaat tcttaatagg ctggtcacac ttcttgcagg agtcagacac
       61 agtcaggaca cagcatggac atgagggccc ccgctcatct cctagggctc ctgctgctct
      121 ggctcccagg tgcccgatgt gacatccaga tgactcagtc tccatcttcc ctgtctgctt
      181 ctgtaggaga cactgtcacc atcacttgcc gggcaagtca gggtcttagc agttctttac
      241 attggtttca acacaaacca gggaaagccc ctaggctcct gatctatgct gcatccagtt
      301 tggcaggtgg ggtcccatca aggttcagcg gcagtggatc tgggacagag ttcactctca
      361 ccatcagcag cctgcagcct gaagattttg caacttatta ctgtctacag tataaaggtt
      421 acccgtacag ttttggccag gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01006785             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:5715:11683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006785
VERSION     KCVT01006785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:5715:11683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..321
                     /note="immunoglobulin light chain variable region"
     V_region        1..321
     V_segment       1..284
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84310.1"
                     /translation="CQQHDSSPWTF"
     J_segment       285..321
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>324
                     /gene="IGKC"
BASE COUNT           88 a           86 c           81 g           69 t
ORIGIN      
        1 acatggggat gacccagtct ccaccctccc tgtctgcatc tgtaggagac agagtcacca
       61 tcacttgcag agccagtcag ggtattcgca actggttggc ctggtatcaa cagagtccag
      121 ggaaagcccc taaactcctg atctataggg catccaattt ggaaacaggg gtcccatcaa
      181 ggttcagtgg aagtggatct gggacagatt tcactctcac catcagcagc ctgcagcctg
      241 aagatatcgc aacatattac tgtcaacagc atgatagttc cccttggacg ttcggccaag
      301 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006786             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24414:11871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006786
VERSION     KCVT01006786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24414:11871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84311.1"
                     /translation="CMQALEFPLTF"
     J_segment       409..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          107 t
ORIGIN      
        1 acatggggtg attgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgctgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gtaggtctag
      181 tcagagcctc ttggatagtg aggatggaaa tacctatttg gaatggcacc ggcagatgcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca agctctagag tttcctctga cgttcggcca
      421 agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01006787             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21108:17415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006787
VERSION     KCVT01006787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21108:17415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84312.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           97 a          125 c          114 g           85 t
ORIGIN      
        1 acatgggggc tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgctgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcttagcctg gtaccagcag aaacctgggc aggctcccag actcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccaggcaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      361 cagcagaaca gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01006788             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18865:13617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006788
VERSION     KCVT01006788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18865:13617"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..376
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84313.1"
                     /translation="CLQFKTFPYSF"
     J_segment       377..414
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT           96 a          116 c          104 g          101 t
ORIGIN      
        1 atggggagac acagtcagga cacagcatgg acatgagggc ccccgctcat ctcctagggc
       61 tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgactcag tctccatctt
      121 ccctgtctgc atctgtagga gacactgtca ccatctcttg ccgggcaagt cagggtatta
      181 gcagttcttt aagttggttt cagcagaaac cagggaaagc ccctaagctc ctcatctatg
      241 ctgcatccac tttggccggt ggggtcccat caaggttcag cggcagtgga tctgggacag
      301 acttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtctac
      361 agtttaaaac tttcccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01006789             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4529:15672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006789
VERSION     KCVT01006789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4529:15672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84314.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01006790             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:6481:19242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006790
VERSION     KCVT01006790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6481:19242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84315.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          102 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtta catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01006791             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12618:9888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006791
VERSION     KCVT01006791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12618:9888"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84316.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtgcggac attgtgatga cccagactcc
      121 actctccctg gccgtcactc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggat
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006792             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9486:4829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006792
VERSION     KCVT01006792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9486:4829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84317.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          122 c          118 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006793             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12984:5000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006793
VERSION     KCVT01006793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12984:5000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84318.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tacgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006794             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14568:13712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006794
VERSION     KCVT01006794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14568:13712"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84319.1"
                     /translation="CQQYDSDSLTF"
     J_segment       378..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           93 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac tcaggacatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01006795             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:15421:8767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006795
VERSION     KCVT01006795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15421:8767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84320.1"
                     /translation="CQQYHSLPLTF"
     J_segment       380..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          105 a          114 c          102 g           98 t
ORIGIN      
        1 acatgggcag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacagttat ttaaattggt atcagcagaa accggggaaa gcccctcaac tcctgatcta
      241 ttattcaaac cgtttggaaa cgggggtccc atcaaggttc agcggcggtg gatctgggac
      301 agaattcact ctcaccatca tcagcctaca acctgaagat tttgtaactt attactgtca
      361 acagtatcat agtttacctc tcactttcgg cggagggacc aaggtggaga tcagacgag
//
LOCUS       KCVT01006796             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:25666:14614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006796
VERSION     KCVT01006796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25666:14614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84321.1"
                     /translation="CMQTLDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagactttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006797             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8884:8394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006797
VERSION     KCVT01006797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8884:8394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84322.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          103 a          126 c          119 g           88 t
ORIGIN      
        1 catggggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct
      241 cccaggctcc tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt
      301 ggcagtgggt ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt
      361 gcagtttatt attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01006798             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7305:16095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006798
VERSION     KCVT01006798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7305:16095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84323.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaagtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006799             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18041:7140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006799
VERSION     KCVT01006799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18041:7140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84324.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcaccttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01006800             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12654:5129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006800
VERSION     KCVT01006800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12654:5129"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84325.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cattttctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006801             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:11663:15453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006801
VERSION     KCVT01006801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11663:15453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84326.1"
                     /translation="CLQYNSSPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacatagcat ggacatgagg gtccctgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgccgggcga gtcagactat
      181 tagcagctgg ttagactggt atcagcagaa accagggaaa gcccctaacc tcctgatctt
      241 taaggcatcc agtttgcaaa gtggggtccc ctcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtct
      361 acagtacaat agtagcccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006802             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16810:12426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006802
VERSION     KCVT01006802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16810:12426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84327.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006803             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6467:19804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006803
VERSION     KCVT01006803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6467:19804"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84328.1"
                     /translation="CQQHDNSPPTF"
     J_segment       385..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>422
                     /gene="IGKC"
BASE COUNT          105 a          118 c          110 g           89 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctc tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcaggg
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaagccccta aactcctgat
      241 ctatagggcg tccaatttgg atacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa tatattactg
      361 tcaacagcat gataattccc ctccgacgtt cggccaaggg accaaggtgg agatcagacg
      421 ag
//
LOCUS       KCVT01006804             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20114:19209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006804
VERSION     KCVT01006804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20114:19209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84329.1"
                     /translation="CQQYNSLPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          108 a          110 c          111 g           99 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctggag ctcctgctgc tctggctccc aggtgccaga tgtgacattg agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcagggcgtt aacgtttatt taaattggta tcaacagaaa ccggggaaag cccctaagcc
      241 cctgatcttt tatgcaaacc gtttggaacg tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaagtta
      361 ttattgtcaa cagtataata gtttaccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01006805             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21923:3844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006805
VERSION     KCVT01006805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21923:3844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..348
                     /note="immunoglobulin light chain variable region"
     V_region        9..348
     V_segment       9..310
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84330.1"
                     /translation="CMQPLEFPWTF"
     J_segment       311..348
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           81 a           91 c           98 g           81 t
ORIGIN      
        1 acatggggga cattgtgctg acccagactc cactctccct gcccgtcacc cttggagagc
       61 cggcctccat ctcctgcagg tctagtcaga gcctcttgga tagtgaggat ggaaacacct
      121 atttggaatg gtacctccag aagccaggcc agtctccaca tctcttgatt tatgaggttt
      181 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      241 cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaacctc
      301 tagagtttcc gtggacgttc ggccagggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006806             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:26104:8054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006806
VERSION     KCVT01006806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:26104:8054"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84331.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtgt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006807             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17196:14693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006807
VERSION     KCVT01006807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17196:14693"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84332.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttagat agtgaggatg gaaacaccta tttggaatgg ttcctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggctt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006808             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:26116:6823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006808
VERSION     KCVT01006808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26116:6823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84333.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           93 a          124 c          120 g           93 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccactggg gatgttgtga tgactcagtc tccgctctcc
      121 ctgcccatca cccctggaca gccggcctcc gtctcctgca ggtctagtca aagccttgtg
      181 cacagcgatg gaaacacata cttgacttgg tatcaacaga agccaggcca acctccaagg
      241 cgcctaattt ttgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgacga tgttggggtt
      361 tattactgcg gccaaggtac acaccttccg tggacgttcg gccaagggac cacggtggaa
      421 ctcaaacgag
//
LOCUS       KCVT01006809             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:9048:9672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006809
VERSION     KCVT01006809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9048:9672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84334.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccagacc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01006810             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24589:9990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006810
VERSION     KCVT01006810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24589:9990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84335.1"
                     /translation="CQQGYTYLYSF"
     J_segment       384..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          115 c          107 g          101 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 ccttgggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacgcagtc
      121 tccatcctcc ctgtccgcat ctgttggaga cacagtcacc atcacttgcc aggcgagtca
      181 agccattgcc aataatttaa attggtatca gcagaaacca ggaaaagccc ctaaagtcct
      241 gatttatagg gcatccagtt tgcaaagtgg gtttccctct cggttcagcg gcagtggatc
      301 tgggacggat ttcactctca ccatcagcag cctgcagcct gaagattttg ccacttatta
      361 ctgtcaacag ggttatactt acctgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006811             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:7462:3458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006811
VERSION     KCVT01006811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7462:3458"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84336.1"
                     /translation="CLQFKTYPNSF"
     J_segment       380..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           96 a          116 c          104 g          102 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatctctt gccgggcaag tcagggtatt
      181 agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctcagct cctcatctat
      241 gctgcatcca gtttggccgg tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattctctc tcaccatcac cagtctgcag cctgaagatt ttgcaactta tttctgtctg
      361 cagtttaaaa cttacccgaa cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01006812             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10582:21666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006812
VERSION     KCVT01006812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10582:21666"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..438
                     /note="immunoglobulin light chain variable region"
     V_region        111..438
     V_segment       111..394
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84337.1"
                     /translation="CQQRNGYPYMYSF"
     J_segment       400..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          106 a          117 c          114 g          104 t
ORIGIN      
        1 acatggggac ttcgtgcagg agttagaccc agtctggacg cagcatggac atcagggtcc
       61 tcgctcagct tctcgggctc ctgctgctct ggctcccagg tgccagatgt gacactcagt
      121 tgatccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc
      181 ggacaagtca ggacattagc acttatttag cctggtatca gcagaaacca gggaaagccc
      241 ctaagctcct gatctataag gcgtccagtt tgcaaagtgg ggtcccatca aggttcagcg
      301 gcagtggatc tgggacaaac ttcactctca ccatcagcag cctgcaggct gaagattttg
      361 cagtttatta ctgtcaacag cgtaatggtt acccgtacat gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006813             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7377:10972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006813
VERSION     KCVT01006813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7377:10972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84338.1"
                     /translation="CQQSYRYPLTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>425
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtga
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagccc ctaaactcct
      241 gatgtatctt gcatccactt tgcagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctcg ccatcagcag cctgcagcct gaagatgctg caacttatta
      361 ctgtcagcag agttatcgtt atccgctcac tttcggtgga gggacccagg tggaaatcaa
      421 tcgag
//
LOCUS       KCVT01006814             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18374:10481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006814
VERSION     KCVT01006814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18374:10481"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84339.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actgtccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtgggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006815             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12359:19907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006815
VERSION     KCVT01006815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12359:19907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84340.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagataggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006816             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15828:11281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006816
VERSION     KCVT01006816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15828:11281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..439
                     /note="immunoglobulin light chain variable region"
     V_region        102..439
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84341.1"
                     /translation="CMQSLDFPLTF"
     J_segment       404..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>444
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtt atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctcct ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacacagatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcagt ctctagattt tccgctcacc ttcggtggag
      421 ggaccaaggt ggagatcaat cgag
//
LOCUS       KCVT01006817             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19279:12125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006817
VERSION     KCVT01006817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19279:12125"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84342.1"
                     /translation="CLQYKSFPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          113 c          100 g          100 t
ORIGIN      
        1 acatggggca gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtggcat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccatcac ttgccggaca agtcaaggta
      181 ttaccaatta tttacattgg tttcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atgaaacatc cagtttggta agtggggtcc catcaaggtt cagcggcagt gcatctggga
      301 cagaattcac tctcaccatc agcagcctac agcctgaaga ttttgcatct tattactgtc
      361 tacagtataa aagtttcccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01006818             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8950:16335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006818
VERSION     KCVT01006818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8950:16335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84343.1"
                     /translation="CQQYNSLPYSF"
     J_segment       406..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          111 a          114 c          118 g          103 t
ORIGIN      
        1 acatggggag gctggacaga cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag gtgccagatg
      121 tgacattgag atgacccagt ctccatcctc cctgtctgct tctgtaggag acagagtcac
      181 catcacttgc cgggcaagtc agggcgttaa cgtttattta aattggtatc agcagaaacc
      241 ggggaaagcc cctaagcccc tgatctttta tgcaaaccgt ttggaacgtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc
      361 tgaagatttt gcaagttatt attgtcaaca gtataatagt ttaccgtaca gttttggcca
      421 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01006819             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20002:18330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006819
VERSION     KCVT01006819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20002:18330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84344.1"
                     /translation="CLQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           87 a          125 c          120 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctcca taggaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgctta caagatatac agcttcctct cactttcggc ggagggacca
      421 agctggagat caaacgag
//
LOCUS       KCVT01006820             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10312:7848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006820
VERSION     KCVT01006820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10312:7848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84345.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcggagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006821             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9157:5865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006821
VERSION     KCVT01006821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9157:5865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84346.1"
                     /translation="CMQGLEFPRTF"
     J_segment       406..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg tgacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc agatctagtc
      181 agagtctctt ggatagtgcg gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tctccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtggctca gacactgatt tcacactaaa gatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag gtctagagtt tcctcggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006822             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14499:17067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006822
VERSION     KCVT01006822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14499:17067"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84347.1"
                     /translation="CLQYKSYPFTF"
     J_segment       388..425
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          116 c          104 g          104 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgcagg agacactgtc accatcactt gccgggcaag
      181 tcagggtatt agtacctatt taaattggtt tcagcagaaa ccagggaaag cccctaagct
      241 cctgatctat gctgcatcta gtctggaaag tggggtccca tcaaggttca gcggcagtgg
      301 ttttggggca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttattgtctc cagtataaaa gttatccatt cactttcggc cccgggacca aactggatat
      421 caaacgag
//
LOCUS       KCVT01006823             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12614:7895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006823
VERSION     KCVT01006823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12614:7895"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84348.1"
                     /translation="CLQYKSYPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          114 c          102 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gcaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 gtattagtac ctatttaaat tggtttcagc agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc atctagtctg gaaagtgggg tcccatcaag gttcagcggc agtggatttg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agatttcgca agttattatt
      361 gtctacagta taaaagttat ccgttcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006824             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23320:16267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006824
VERSION     KCVT01006824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23320:16267"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84349.1"
                     /translation="FMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattatgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatattgggg tttattactt catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006825             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:15617:13620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006825
VERSION     KCVT01006825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15617:13620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84350.1"
                     /translation="CMQGTQLPYSF"
     J_segment       398..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           92 a          121 c          122 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcaactcc
       61 tggggctact ggtgctctgg ctccctggga ccaggggaga tattgtgatg acccagattc
      121 cactctccct acccgtcacc cctggagagc cggcctccat ctcctgtagg tctagccaga
      181 gcctccttca tagtgatgga tccacctatt tggactggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatctat ttgggttcca agcgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag tcgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caaggtacac agcttccgta cagttttggc caggggacca
      421 aagtggagat caaacgag
//
LOCUS       KCVT01006826             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15396:12152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006826
VERSION     KCVT01006826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15396:12152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84351.1"
                     /translation="CQQHNSYPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          122 c          100 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggtattacga attctttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atctattaca catccaattt agaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatagtta cccattcact ttcggccccg ggaccaaact ggataacaaa
      421 cgag
//
LOCUS       KCVT01006827             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13537:12454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006827
VERSION     KCVT01006827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13537:12454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84352.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006828             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:17805:8651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006828
VERSION     KCVT01006828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17805:8651"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84353.1"
                     /translation="CQQHDNFPYIF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          113 a          115 c          103 g           95 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 aacatattag cgactggttg gcctggtatc aacagaaacc agggaaagcc cctaagctcc
      241 tgatctatcg gacttccaat ttggaaacag gagtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagta gctttcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgataat ttcccgtaca tttttgacca ggggaccaaa ctggagatca
      421 aacgag
//
LOCUS       KCVT01006829             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20244:4124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006829
VERSION     KCVT01006829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20244:4124"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84354.1"
                     /translation="CMQSIKDPFTF"
     J_segment       398..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          102 a          121 c          109 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcggactgtt gatgctctgg gtccctggat ccagtgggga tattgtgatg acccagaccc
      121 cactctcggt gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctcca tagtaatgga gacacctatt tacattggta ccttcagagg tcaggccagt
      241 ctccacggct cctgatctat aaagtaacca atcggctacc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaggata
      361 ttggtgttta tttctgcatg caaagtataa aagatccatt cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01006830             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20295:6516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006830
VERSION     KCVT01006830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20295:6516"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84355.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          111 c          105 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcgt ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006831             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16590:20375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006831
VERSION     KCVT01006831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16590:20375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    18..339
                     /note="immunoglobulin light chain variable region"
     V_region        18..339
     V_segment       18..292
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <279..>311
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84356.1"
                     /translation="CQQHNGYPPTF"
     J_segment       305..339
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        340..>342
                     /gene="IGKC"
BASE COUNT           91 a           92 c           86 g           73 t
ORIGIN      
        1 acaggggggc cagatgtgac atccagatga cccagtctcc atcctccctg tctgcatctg
       61 taggagacac agtcaccatc acttgtcggg caagtcaggg cattaccaat gatttagcct
      121 ggtatcagca gagaccaggg aaagccccga agcccctgat ctattacgca tccaatttgg
      181 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc actctcacca
      241 tcagcagcct gcagcctgaa gattttgcaa cttattattg tcaacagcat aatggatacc
      301 ctccgacgtt cggccaaggg accagggtgg aaatcaaacg ag
//
LOCUS       KCVT01006832             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10644:19947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006832
VERSION     KCVT01006832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10644:19947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84357.1"
                     /translation="CQQYDSDPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          116 c          113 g           93 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gacccgttca ctttcggtgg agggaccaag gtagagatca
      421 aacgag
//
LOCUS       KCVT01006833             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10522:5975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006833
VERSION     KCVT01006833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10522:5975"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84358.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           92 a          117 c          128 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcgc ccttggagag ccggcctcca tctcctgtgg gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaggccaggc
      241 cagtctccac agctgttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatttctg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aattcaaacg ag
//
LOCUS       KCVT01006834             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13369:17925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006834
VERSION     KCVT01006834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13369:17925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84359.1"
                     /translation="CQQYNSLPYIF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          112 c          102 g           99 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg tcggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aacccctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttatttctg
      361 tcaacagtat aatagtttac cgtacatttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006835             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:4029:7843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006835
VERSION     KCVT01006835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4029:7843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84360.1"
                     /translation="CQQYNSEPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaactag ggaaaccccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga gccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006836             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:10302:3190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006836
VERSION     KCVT01006836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10302:3190"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84361.1"
                     /translation="CQQHDDSPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           87 t
ORIGIN      
        1 acatggggca gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacgt ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgtg ggagacagag tcaccatcac ttgcacagcc agtcacgata
      181 ttaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaaa ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcgaggtt cggtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006837             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6626:3915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006837
VERSION     KCVT01006837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6626:3915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84362.1"
                     /translation="CMQALDFPFTF"
     J_segment       322..359
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           84 a           98 c           96 g           84 t
ORIGIN      
        1 acatggggga tccagtgggg acattgtgat gacccagact cccccctccc tgcccgtcac
       61 ccttggagag gcggcctcca tctcctgtag gtctagtcag agcctcttcg atactgaaga
      121 aggaaacacc tatttggagt ggtacctgca gaggccaggc cagactccac agctcttgat
      181 ttatcaggtt tccaatcggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttggac tttattactg
      301 catgcaggct ctagactttc cattcacttt cggccccggg accaaactgg atatcaaacg
      361 ag
//
LOCUS       KCVT01006838             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21204:5276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006838
VERSION     KCVT01006838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21204:5276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84363.1"
                     /translation="CQQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          109 c          105 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattggcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctaa
      241 tctattatgc aaaccgtttg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggaatt cactctcacc atcagcagcc tgcaacctga agattttgca atttattatt
      361 gtcaacagta taatagttta ccgtacactt ttggccaggg gaccaaagtg gacatcaaac
      421 gag
//
LOCUS       KCVT01006839             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18335:10176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006839
VERSION     KCVT01006839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18335:10176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84364.1"
                     /translation="CLQGYIPPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          116 c          109 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaacctg gaaaacctcc taaccgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc gacttattac
      361 tgtctacagg gctatattcc cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006840             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:27455:8749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006840
VERSION     KCVT01006840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27455:8749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84365.1"
                     /translation="CQHSFRTPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          117 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccgt cacttgcagg gctagtgaga
      181 gcgttagcac caaattacat tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc gtccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gaacagattt cactctcacc atcagcagcc tgcagcctga agatgttgca actttttact
      361 gtcagcatag ttttcgtacc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006841             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13250:14693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006841
VERSION     KCVT01006841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13250:14693"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84366.1"
                     /translation="CLQFKTFPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          118 c          106 g          102 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tctcttgccg ggcaagtcag
      181 ggtattagca gttctttaag ttggtttcag cagaaaccag ggaaagcccc taagctcctc
      241 atctatgctg catccacttt ggccggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagact tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ttaaaacttt cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006842             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13440:2834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006842
VERSION     KCVT01006842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13440:2834"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84367.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          109 c          112 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtcggagaca gagtcagcat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatgc aaaccgtttg gagagtgggg tcccatcaag gttcagcggc agtgggtctg
      301 ggacagaatt cactctcatc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006843             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:27990:9907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006843
VERSION     KCVT01006843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:27990:9907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84368.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgtt aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006844             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:12672:20576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006844
VERSION     KCVT01006844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12672:20576"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84369.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgagattt ccaaccgggc ctcgggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcacagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006845             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22020:7493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006845
VERSION     KCVT01006845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22020:7493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84370.1"
                     /translation="CQQYSSYPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          118 c          107 g           96 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagtt
       61 cctggggctc ctgctgctct ggatcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga caaagtcacc atcacttgcc gagccagtca
      181 gggtattagc agcttgttag cctggtatca gcagaaacca gggaaagccc ctaagtccct
      241 gatctataag gcatccagtt tgcaaagtgg ggtcccttca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca gcatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatagtagtt acccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01006846             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16102:6425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006846
VERSION     KCVT01006846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16102:6425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..378
                     /note="immunoglobulin light chain variable region"
     V_region        57..378
     V_segment       57..335
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <318..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84371.1"
                     /translation="CQQGYSYPRTF"
     J_segment       343..378
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>381
                     /gene="IGKC"
BASE COUNT           91 a          111 c           92 g           87 t
ORIGIN      
        1 acatgggcgc tcagctcctt gggctcctgc tgctctggct cccaggtgcc agatgtgaca
       61 tccagatgac gcagtctcca tcctccctgt ccgcatccgt aggagacaca gtcaccatca
      121 cttgccaggc gagtcaaggc attgacaata atttaaattg gtatcagcaa aaaccaggga
      181 aagcccctaa actcctgatc tttggggcat ccactctcca aagtgggact ccctcgcggt
      241 tcagcggcag tgattctggg acggatttca ctctcaccat cagcagcctg cagcctgaag
      301 attttgccac ttatttctgt caacagggtt atagttaccc tcggacgttc ggccaaggga
      361 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006847             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9605:12266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006847
VERSION     KCVT01006847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9605:12266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84372.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          125 c          119 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag aaccggcctc catctcctgc aggtctagtc
      181 agagcctctt cgatagtgag gaaggaacca cctttttgga atggtacctg cagaggccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gttgaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccacggt ggaaatcaaa cgag
//
LOCUS       KCVT01006848             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15353:11340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006848
VERSION     KCVT01006848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15353:11340"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84373.1"
                     /translation="CQQYDSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006849             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9481:22879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006849
VERSION     KCVT01006849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9481:22879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..416
                     /note="immunoglobulin light chain variable region"
     V_region        98..416
     V_segment       98..380
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84374.1"
                     /translation="CYQHSRGWAF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g           84 t
ORIGIN      
        1 acatggggag ctgctaggtt agtacccaga aggaaccatg gaagccccag ctcagcttct
       61 ctgccttctg ctactctggc tcccaggtac caccggacaa attatattga cacagtctcc
      121 agccaccctg tctttggcac caggggaaag agccactctc tcctgcaggg ccagtgagaa
      181 tgttggcagc tacttagcct ggtaccagca gaaccctggg caggctccca ggctcctcgt
      241 ccacagtgcg tccagcaggg ccactgacat cccagacagg ttcagttgca gtgggtctcg
      301 gacagagttc accctcacca tcagcagtct ggagcctgaa gatgttggag tctattactg
      361 ctatcaacat agcagggggt gggcgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006850             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:22130:17443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006850
VERSION     KCVT01006850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22130:17443"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84375.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          119 c          125 g          103 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccagtctcc ctgcccgtca ccctgggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggcacctgc agaggccagg
      241 ccagtctcca cagctcttga tttatgaggt ttcctatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttc ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01006851             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14535:17925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006851
VERSION     KCVT01006851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14535:17925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..384
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84376.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       394..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>431
                     /gene="IGKC"
BASE COUNT          101 a          116 c          113 g          101 t
ORIGIN      
        1 acatgggggg agttagaccc agtctggacg cagcatggac atcagggtcc tcgctcagct
       61 tctcgggctc ctgctgctct ggctcccagg tgccagatgt gacattcagt tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcaagtca
      181 ggacattggc aattatttag cctggtatca gcagaaacca gggaaagccc ctaacctcct
      241 gatctataag gcgtccagtt tacaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagtttatta
      361 ctgtcaacag cgtaatagtt acccgtacat gtgcagtttt ggcccgggga ccaaagtgga
      421 gatccgacga g
//
LOCUS       KCVT01006852             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24463:2630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006852
VERSION     KCVT01006852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24463:2630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84377.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          125 c          112 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca acagcttagc ctggtaccaa caaaaacctg ggcagcctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagagg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cggg
//
LOCUS       KCVT01006853             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6997:6890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006853
VERSION     KCVT01006853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6997:6890"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84378.1"
                     /translation="CMQSLEFPWTS"
     J_segment       402..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           90 a          118 c          125 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgaagat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttggtt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttatttctgc atgcagagtc tggagtttcc ttggacgtcc ggccaaggga
      421 ccaaggtgga agtcaagcga g
//
LOCUS       KCVT01006854             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7588:8959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006854
VERSION     KCVT01006854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7588:8959"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..406
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84379.1"
                     /translation="CQQYTSFPLTF"
     J_segment       409..444
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          108 a          125 c          116 g           98 t
ORIGIN      
        1 acatggggga ggctggacag acttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctggggc tcctgctgct ctggctccca ggtgccagat
      121 gtgacattca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      181 ctgtcacttg ccgggcaagt gaggacgtta gcagtcattt aaattggtat caacagaaac
      241 cggggaaagc ccctaagctc ctgatctatt ttgcagaccg tttggaaagt ggggtcccat
      301 caaggttcag cggcagtgga tctgggacag aattcagtct caccatcagc agcctgcaac
      361 ctgaggactt tgcaacttat cactgtcaac agtacactag tttccccctc actttcggcc
      421 ccgggaccaa actggatatc aaacgag
//
LOCUS       KCVT01006855             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15004:3606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006855
VERSION     KCVT01006855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15004:3606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..395
                     /note="immunoglobulin light chain variable region"
     V_region        56..395
     V_segment       56..357
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <335..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84380.1"
                     /translation="CMQPLEFPWTF"
     J_segment       358..395
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>398
                     /gene="IGKC"
BASE COUNT           87 a          106 c          112 g           93 t
ORIGIN      
        1 acatggggct cagctcctgg gactgctaat gctctggctc cctggatcca gtggggacat
       61 tgtgctgacc cagactccac tctccctgcc cgtcaccctt ggagagccgg cctccatctc
      121 ctgcaggtct agtcagagcc tcttggatag tgaggatgga aacacctatt tggaatggta
      181 cctccagaag ccaggccagt ctccacatct cttgatttat gaggtttcca accgggcctc
      241 tggagtccca gacaggttca gtggcagtgg gtcagacact gatttcacac tgaaaatcag
      301 cagagtggag gctgaggatg ttggggttta ttactgcatg caacctctag agtttccgtg
      361 gacgttcggc caggggacca aggtggaaat caaacgag
//
LOCUS       KCVT01006856             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20804:2969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006856
VERSION     KCVT01006856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20804:2969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84381.1"
                     /translation="CMQALDFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgctga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatt ttctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc cgaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgtttggatt tattactgca tgcaagctct agactttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006857             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15894:13457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006857
VERSION     KCVT01006857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15894:13457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84382.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagagt
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgagatt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcacagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006858             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15024:9148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006858
VERSION     KCVT01006858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15024:9148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84383.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctgca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagaatttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006859             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12126:9938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006859
VERSION     KCVT01006859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12126:9938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84384.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag ccaggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006860             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:9190:8328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006860
VERSION     KCVT01006860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9190:8328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84385.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcaac agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca atttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006861             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19951:15410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006861
VERSION     KCVT01006861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19951:15410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84386.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          119 c          116 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggccttcatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006862             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11852:19569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006862
VERSION     KCVT01006862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11852:19569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84387.1"
                     /translation="CQHSFRTPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          117 c          110 g           97 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggac acagcatgga catgagggcc tctgctcagc
       61 tcctagggct cctgctgctc tggctcccag gcgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac cgtcacttgc agggctagtg
      181 agagcgttag caccaaatta cattggtatc aacagaaacc agggaaagcc cctaagctcc
      241 tgatctttgc tgcgtccact ttgcaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctggaacaga tttcactctc accatcagca gcctgcagcc tgaagatgtt gcaacttttt
      361 actgtcagca tagttttcgt accccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006863             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:10672:10439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006863
VERSION     KCVT01006863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10672:10439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84388.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcactactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006864             562 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7779:13753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006864
VERSION     KCVT01006864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 562)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7779:13753"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    238..559
                     /note="immunoglobulin light chain variable region"
     V_region        238..559
     V_segment       238..522
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <499..>531
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84389.1"
                     /translation="CQQHDDSPRTF"
     J_segment       524..559
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        560..>562
                     /gene="IGKC"
BASE COUNT          138 a          164 c          143 g          117 t
ORIGIN      
        1 acatgggggc ccctgtgctg agttactgag atgagccagc cctgcagctg tgcccagcca
       61 gccccatccc ctgatgattt gcatgttccc agagcacagc cccctgccct gaagacttat
      121 taatagactg gtcacaccct gtgcaggagt cagtctcaga caggacacag catggacacg
      181 agggtccccg ctcagctcct ggggctcctg ttgctctggc tcccaggtgc cagatgtgac
      241 atccagatga cccagtctcc atcctccctg tctgcatctg taggagacag agtcaccatc
      301 acttgcagag ccagtcagga tattaacaac tggttggcct ggtatcaaca gaaaccaggg
      361 aaagccccta aggtcctgat ctatagggca tccaatttgg aaacaggggt cccatccagg
      421 ttcagtggaa gtggatctgg gacagatttc actctcacca tcagcagcct gcagcctgaa
      481 gatatcgcaa catattactg tcaacagcat gatgattcgc ctcggacgtt cggccaaggg
      541 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006865             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18675:15851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006865
VERSION     KCVT01006865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18675:15851"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..456
                     /note="immunoglobulin light chain variable region"
     V_region        117..456
     V_segment       117..418
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84390.1"
                     /translation="CMQPLEFPWTF"
     J_segment       419..456
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>459
                     /gene="IGKC"
BASE COUNT          103 a          122 c          129 g          105 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggatc acgactcctc aggtcacctt ctcacaatga
       61 ggctccctgc tcagctcctg ggactgctaa tgctctggct ccctggatcc agtggggaca
      121 ttgtgatgac ccagactcca ctgtccctgc ccgtcaccct tggagagccg gcctccatct
      181 cctgtgggtc tagtcagagc ctcttggata gtgaggatgg aaacacctat ttggaatggt
      241 acctgcagaa gccaggccag tctccacagc tcttgattta tgaggtttcc aaccgggcct
      301 ctggagtccc agacaggttc agtggcagtg ggtcagacac tgatttcaca ctgaaaatca
      361 gcagagtgga ggctgaggat gttggggttt attactgcat gcaacctcta gagtttccgt
      421 ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006866             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:5628:6126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006866
VERSION     KCVT01006866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5628:6126"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84391.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat gcagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttgtagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgcgg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006867             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10283:4755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006867
VERSION     KCVT01006867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10283:4755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84392.1"
                     /translation="CQRYSYSTWTF"
     J_segment       387..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          120 c          116 g           91 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat attgactcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcagctt ggtttggtac cagcagaaac ctgggcaggc ccccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt tgcagtatat
      361 tactgtcaga ggtatagtta ctccacgtgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01006868             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12249:8687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006868
VERSION     KCVT01006868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12249:8687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84393.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          124 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctccggtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006869             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14697:18151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006869
VERSION     KCVT01006869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14697:18151"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84394.1"
                     /translation="CMQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           85 a          124 c          122 g          107 t
ORIGIN      
        1 acatgggtga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgctg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagagg ccaggccagt
      241 ctccacaact tctggtctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcatg caagatatac agcttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01006870             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21464:9415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006870
VERSION     KCVT01006870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21464:9415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84395.1"
                     /translation="CQQYNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          117 c          108 g           94 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataataatt attctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006871             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13134:12542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006871
VERSION     KCVT01006871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13134:12542"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-11"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84396.1"
                     /translation="CQHNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcaactta gcctggtacc agcagagacc tgggcagtct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca taacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006872             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11501:15033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006872
VERSION     KCVT01006872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11501:15033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84397.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006873             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7246:15472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006873
VERSION     KCVT01006873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7246:15472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84398.1"
                     /translation="CQQHDDSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          119 c          107 g           87 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ctggttggcc tggtatcaac agaaaccagg aaaagcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgatgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006874             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21671:20568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006874
VERSION     KCVT01006874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21671:20568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84399.1"
                     /translation="CHHTYGPPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          121 c          106 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag gtcaagtgag
      181 agcatttaca actatttaca ttggtaccag cagaaaccag ggaaagcccc taagctcctg
      241 atctatgctg catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacaggtt tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcaccata cttatggtcc ccctcggacg ttcggccaag ggaccaaggt ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006875             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9393:7253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006875
VERSION     KCVT01006875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9393:7253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84400.1"
                     /translation="CMQALDFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          123 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgcg
      361 gatgttgggg tttattactg catgcaagct ctagactttc ccctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006876             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8319:4439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006876
VERSION     KCVT01006876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8319:4439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84401.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          104 a          126 c          118 g           88 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct
      241 cccaggctcc tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt
      301 ggcagtgggt ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt
      361 gcagtttatt attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01006877             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24826:8025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006877
VERSION     KCVT01006877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24826:8025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84402.1"
                     /translation="CQQYNSDWRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           92 t
ORIGIN      
        1 acatgggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgact ggcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006878             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22898:18115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006878
VERSION     KCVT01006878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22898:18115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84403.1"
                     /translation="CMQDIQLPLTF"
     J_segment       394..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           89 a          123 c          120 g          102 t
ORIGIN      
        1 acatggggag gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 gctgctggtg ctctggctcc ctgggaccag tggggatatt gtgatgactc agactccact
      121 ctccctgccc gtcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggataca cctatttgtt ttggtacctg cagaagccag gccagtctcc
      241 acaactcctg atctacttgg gttccaaccg ggcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagccgg gtggaggctg aagatgttgg
      361 ggtttattac tgcatgcaag atatacagct tccgctcact ttcggcggag ggaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01006879             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21499:11463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006879
VERSION     KCVT01006879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21499:11463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84404.1"
                     /translation="CLQGYSAPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          117 c          105 g           97 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcttcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa actcctcagc gcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatct gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggttat agtgccccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01006880             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16738:16399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006880
VERSION     KCVT01006880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16738:16399"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84405.1"
                     /translation="CQQYDKSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          117 c          113 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagggt caccatcact tgcagagcca gtcagggtat
      181 cagcaacttg ttggcctggt atcaacagaa accagggaga gcccctaacc tcctgatgta
      241 tagggcgtcc aatttgcaag gaggggtccc atcaaggttc agaggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaggat gtcgctacat attactgtca
      361 acagtatgat aagtcccctc cgacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006881             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22273:9655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006881
VERSION     KCVT01006881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22273:9655"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84406.1"
                     /translation="CQQYTSFPLTF"
     J_segment       386..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          120 c          107 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtgag
      181 gacgttagca gtcatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattttg caaaccgttt ggaaagtggg gtcccattaa ggttcagcgg cagtggatct
      301 gggacagaat tcagtctcac catcagcagc ctgcaacctg aggactttgc aacttatcac
      361 tgtcaacagt acactagttt ccccctcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01006882             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22515:19664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006882
VERSION     KCVT01006882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22515:19664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84407.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          118 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaccgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggcttg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccagggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006883             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19252:10880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006883
VERSION     KCVT01006883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19252:10880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84408.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          115 c          107 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggctca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc agaaaccagg aaaagccccg aaggccttga
      241 tctattacgc atccatttta gaaagtgcgg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga cgattttgca gtttattact
      361 gtcaacagta taacagtgac ccgtacactt ttggcccggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006884             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18295:13076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006884
VERSION     KCVT01006884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18295:13076"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84409.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          117 c          109 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatatatta cggatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006885             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14618:14898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006885
VERSION     KCVT01006885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14618:14898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84410.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          100 a          115 c          118 g           99 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtggtgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga caacctccta
      241 aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac gatggtgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01006886             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12675:10448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006886
VERSION     KCVT01006886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12675:10448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84411.1"
                     /translation="CQQYNTLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          112 c          103 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacgtt cagatgaccc agtctccatc
      121 ctacctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacgtttat ttaaattggt atcaccagaa accggggaaa gcccctaacc tcctgatcta
      241 ttatgcaaac cgtttggaaa atggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcgactt attactgtca
      361 acagtataat actttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006887             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24991:13801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006887
VERSION     KCVT01006887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24991:13801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84412.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          121 g          106 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006888             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:27816:16140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006888
VERSION     KCVT01006888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:27816:16140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84413.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgtgtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006889             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:20322:11080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006889
VERSION     KCVT01006889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20322:11080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84414.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccggactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01006890             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13621:11792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006890
VERSION     KCVT01006890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13621:11792"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84415.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atatcaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006891             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:10335:19791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006891
VERSION     KCVT01006891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10335:19791"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..414
                     /note="immunoglobulin light chain variable region"
     V_region        100..414
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84416.1"
                     /translation="CQQYNTLPLTF"
     J_segment       384..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acactcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaaca tttatttaaa ttggtatcag cagaaaccgg ggaaagcccc tgagctcctg
      241 atctattatg caaaccgttt ggaaactggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcagtctcac catcagcagc ctgcaacctg aggactttgc aacttattac
      361 tgtcaacagt ataatacttt accgctcact ttcggcggag ggaccaaggt ggaggtcaga
      421 cgag
//
LOCUS       KCVT01006892             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20086:10306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006892
VERSION     KCVT01006892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20086:10306"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84417.1"
                     /translation="CQQYDSDLFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          115 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcagacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc tgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01006893             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:26011:11263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006893
VERSION     KCVT01006893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26011:11263"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84418.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          117 c          114 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg cgtctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacccgtt cactttcggt ggagggacca aggtagagat
      421 caaacgag
//
LOCUS       KCVT01006894             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14318:20864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006894
VERSION     KCVT01006894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14318:20864"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84419.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggac
      421 cacagtggag attaaacgag
//
LOCUS       KCVT01006895             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11283:11778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006895
VERSION     KCVT01006895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11283:11778"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84420.1"
                     /translation="CLQGYITPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          113 c          112 g           99 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacttccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tgcaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ctgtctacag ggttatatta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01006896             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18709:17316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006896
VERSION     KCVT01006896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18709:17316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..368
                     /note="immunoglobulin light chain variable region"
     V_region        91..368
     V_segment       91..329
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84421.1"
                     /translation="CQQYNSDLFTF"
     J_segment       333..368
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>371
                     /gene="IGKC"
BASE COUNT           94 a           97 c          101 g           79 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggagacaga gtcaccatca cttgtcgggc
      121 gagtcaggac attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa
      181 gcccttgatc tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag
      241 tggatctggg acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac
      301 ttattactgt caacagtata acagtgacct gttcactttc ggtggaggga ccaaggtgga
      361 gatcaaacga g
//
LOCUS       KCVT01006897             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:9873:2578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006897
VERSION     KCVT01006897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9873:2578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..276
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84422.1"
                     /translation="CQQYDSFPLTF"
     J_segment       279..314
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>317
                     /gene="IGKC"
BASE COUNT           78 a           83 c           77 g           79 t
ORIGIN      
        1 acatgggcag tctccatcct ccctgtctgc ttctgtggga gacagagtca ccatcacttg
       61 ccgggctagt caggacatta gtaatttttt aaattggtat cagcagaaac cggggaaagc
      121 ccctaagctc ctgatctatt atggaaaccg tttgggaagc ggggtcccat caaggttcag
      181 cggcagtgga tctgggacag aattcactct caccatcagc agcctgcaac ctgaggattt
      241 tgcgacttat cattgtcagc agtatgatag tttccccctc actttcggcc ccgggaccaa
      301 actggatatc aaacgag
//
LOCUS       KCVT01006898             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16124:14425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006898
VERSION     KCVT01006898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16124:14425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84423.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcac cagcagctta gcctggtatc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006899             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9852:9985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006899
VERSION     KCVT01006899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9852:9985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84424.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006900             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24523:8664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006900
VERSION     KCVT01006900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24523:8664"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84425.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          125 c          112 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct gactcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtctattt
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006901             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7476:22136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006901
VERSION     KCVT01006901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7476:22136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84426.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggt ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006902             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20233:2763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006902
VERSION     KCVT01006902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20233:2763"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84427.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcctgga tagtgaggat ggaaacactt atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttg ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006903             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7429:16876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006903
VERSION     KCVT01006903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7429:16876"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84428.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggccccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006904             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22251:16431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006904
VERSION     KCVT01006904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22251:16431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..341
                     /note="immunoglobulin light chain variable region"
     V_region        137..341
     V_segment       137..303
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84429.1"
                     /translation="CLQSKNSPWTF"
     J_segment       304..341
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           78 a           94 c           90 g           82 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag gacaacctcc taaacccctg atttaccaag catccaataa
      181 agaaactggg gtcccagcca ggttcagcgg cagtgggtct gggaccgatt tcaccctcac
      241 aattaatcct gtggaagctg acgatgctgc agattattac tgtctgcaga gtaagaattc
      301 tccgtggacg tttggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006905             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25469:10750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006905
VERSION     KCVT01006905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25469:10750"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84430.1"
                     /translation="CLQYKSFPYTF"
     J_segment       386..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c           99 g           96 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccggacaa gtcaaggtat
      181 taccaattat ttacactggt ttcagcagaa accagggaga gcccctaagc tcctgatcta
      241 tgaaacatcc agtttgacaa gtggggtccc atcaaggttc agcggcagtg cgtctgggac
      301 agaattcaat ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agtttcccgt acacctttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01006906             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18404:16105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006906
VERSION     KCVT01006906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18404:16105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84431.1"
                     /translation="CIQSLEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          111 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccactgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cttctcctgt aggtctagtc
      181 acagcctctt ggatagtgag gatggatata tccatttgga ttggtatctg cagaagccag
      241 gccagtctcc acacctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggtttagtgg cagtgggtca gacactgatt tcacactgaa aatcagcagg gtggaggctg
      361 aggatgttgg ggtttactac tgcatacaat ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006907             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:26026:14589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006907
VERSION     KCVT01006907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26026:14589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84432.1"
                     /translation="CQQHDNSPWTF"
     J_segment       378..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          107 a          116 c          109 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccccca gctcctgggg
       61 ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccgtcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag tcagggtatt
      181 agcaactggt tggcctggta tcaacagaaa ccagggaaag cccctaagct cctgatctat
      241 agggcatcca atttggaaac aggggtcccg tcaaggttca gtggaagtgg atctgggaca
      301 gatttcactc tcaccatcag cagcctgcag cctgaagatc tcgcaacata ttattgtcaa
      361 caacatgata attccccgtg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01006908             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21599:12437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006908
VERSION     KCVT01006908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21599:12437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84433.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc gttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac gctgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga gatcaaacga g
//
LOCUS       KCVT01006909             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19488:12580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006909
VERSION     KCVT01006909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19488:12580"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84434.1"
                     /translation="CMPALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgccagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006910             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:6767:5372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006910
VERSION     KCVT01006910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:6767:5372"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84435.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 tcctctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006911             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24993:10769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006911
VERSION     KCVT01006911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24993:10769"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..374
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84436.1"
                     /translation="CQQNSNWPLTF"
     J_segment       375..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           97 a          122 c          112 g           83 t
ORIGIN      
        1 acatggggag ttaggaccca gagggaacca tggaagcccc agcacagctt ctcttcctcc
       61 tgctgctctg gctcccagat accaccggag aaatagtgct gacgcagtct ccagccaccc
      121 tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag agtgtcagca
      181 gcagcttagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc atctatggtg
      241 catccaacag ggccactggc atcccaggca ggttcagtgg cagtgggtct gggacagagt
      301 tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat tgtcagcaga
      361 acagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006912             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:18422:17366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006912
VERSION     KCVT01006912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18422:17366"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84437.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          117 c          108 g           87 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagga
      181 tattaacacc tggttggcct ggtatcaaca gaagccaggg aaagccccta aggtcctgat
      241 ctataggaca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcaacagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006913             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:18514:9428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006913
VERSION     KCVT01006913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18514:9428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..399
                     /note="immunoglobulin light chain variable region"
     V_region        80..399
     V_segment       80..363
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84438.1"
                     /translation="CLQFKSYPNSF"
     J_segment       366..399
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>404
                     /gene="IGKC"
BASE COUNT           94 a          111 c          102 g           97 t
ORIGIN      
        1 acatggggac agcatggaca tgagggcccc cgctcatctc ctagggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gactcagtct ccatcttccc tgtctgcatc
      121 tgtaggagac actgtcacca tcacttgccg ggcaagtcag ggtattagca gttctttaag
      181 ttggtttcag cagaaaccag ggaaagcccc taagctcctc atctatgctg catccacttt
      241 ggccggtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtctacagt ttaaaagtta
      361 cccgaacagt tttggccagg ggaccaaagt ggagatcaag cgag
//
LOCUS       KCVT01006914             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16257:9649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006914
VERSION     KCVT01006914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16257:9649"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84439.1"
                     /translation="CQQGYRYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtgggagaca cagtcacgat cacttgccag acgagtcaag
      181 acattgacat taatttaagt tactatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atcccgtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatcgttac ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006915             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:25117:6119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006915
VERSION     KCVT01006915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25117:6119"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..442
                     /note="immunoglobulin light chain variable region"
     V_region        100..442
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84440.1"
                     /translation="CMQALEFPPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          122 c          117 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagaat
      121 ccactctccc tgcccgtcac ccttggagag ccggccttca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattattg catgcaagct ctagagtttc ctccattcac tttcggcccc
      421 gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01006916             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:11598:8253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006916
VERSION     KCVT01006916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11598:8253"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84441.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006917             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:11628:4326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006917
VERSION     KCVT01006917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11628:4326"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84442.1"
                     /translation="CMQAREFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          127 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt caagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aggccgggcc
      241 agtctccaca gctcttgatg tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc gagaatttcc gtggacgttc ggccacggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006918             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24486:4557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006918
VERSION     KCVT01006918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24486:4557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84443.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006919             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13906:7472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006919
VERSION     KCVT01006919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13906:7472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..348
                     /note="immunoglobulin light chain variable region"
     V_region        9..348
     V_segment       9..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84444.1"
                     /translation="CMQVLEFPLTF"
     J_segment       312..348
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           79 a           89 c           98 g           85 t
ORIGIN      
        1 acatggggga cattgtgatg acccagactc cactctccct gcccgtcacc cttggagagc
       61 cggcctccat ctcctgcagg tctagtcaga gcctcttgga tagtgaggat ggaaacacct
      121 atttggaatg gttcctgcag aagccaggcc agtctccaca gctcttgatt tatgacgttt
      181 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      241 cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaagttc
      301 tagagtttcc tctcactttc ggtggaggga ccacggtgga gatcaaacga g
//
LOCUS       KCVT01006920             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:26835:8411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006920
VERSION     KCVT01006920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:26835:8411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84445.1"
                     /translation="CQQYDSDTRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          113 g           91 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgaca cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006921             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:26376:20281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006921
VERSION     KCVT01006921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26376:20281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84446.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          117 c          125 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaatacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccgca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcattgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006922             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10368:8704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006922
VERSION     KCVT01006922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10368:8704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84447.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaaga ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cctattactg
      361 tcaacagtat gacagtgatc cgttcacttt cggtgggggg accaaggtag acatcaaacg
      421 ag
//
LOCUS       KCVT01006923             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:5703:9997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006923
VERSION     KCVT01006923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5703:9997"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84448.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 ccgtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt gtattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gattaaacga g
//
LOCUS       KCVT01006924             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15310:9382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006924
VERSION     KCVT01006924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15310:9382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84449.1"
                     /translation="CLQPLEFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctacagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgctt gcaacctcta gagtttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01006925             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19007:20256
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006925
VERSION     KCVT01006925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19007:20256"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84450.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaggccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca atatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006926             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15089:15206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006926
VERSION     KCVT01006926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15089:15206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84451.1"
                     /translation="CLQGYSAPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          118 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcttcg gcaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agagaccagg aaaaatgcct cagcgcctga
      241 tctatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc gtcagcagcc tgcagcctga agattttgca gcttattact
      361 gtctacaggg ttatagtgcc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006927             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16583:19828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006927
VERSION     KCVT01006927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16583:19828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84452.1"
                     /translation="CMQALEFPYTF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctga ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctcctca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttacactttt ggccagggga
      421 ccacagtgga gatcaaacga g
//
LOCUS       KCVT01006928             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:19586:11255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006928
VERSION     KCVT01006928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19586:11255"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84453.1"
                     /translation="CQQVYGNPFTF"
     J_segment       383..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           97 a          120 c          104 g          101 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccctg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgat atccagatga cccagtctcc
      121 atctgccttg tctgcatctg taggagacag agtcaccatc tcttgccgga caagtcagaa
      181 catttatagt tatttagcgt ggtatcagca gaagccaggg aaagcccctg agctcctgat
      241 ctatgctgta tccagattgc aaagtgggat tccctctcgc ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattctgcaa cttactactg
      361 tcaacaggtt tatggcaacc ccttcacctt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01006929             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:16470:7453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006929
VERSION     KCVT01006929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16470:7453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..463
                     /note="immunoglobulin light chain variable region"
     V_region        124..463
     V_segment       124..425
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <403..>435
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84454.1"
                     /translation="CMQALEFPFTF"
     J_segment       426..463
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        464..>466
                     /gene="IGKC"
BASE COUNT          106 a          126 c          123 g          111 t
ORIGIN      
        1 acatgggaag agtggtatca acgagtcatg ggggatcacg actcctcagg tcaccttctc
       61 acaatgaggc tccctgctca gctcctggga ctgctaatgc tctggctccc tggatccact
      121 ggggacattg tgatgaccca gactccactc tccctgcccg tcacccttgg agagccggcc
      181 tccatctcct gcaggtctag tcagagcctc ttggatagtg aggatgaaaa cacctatttg
      241 gaatggtacc tgcagaagcc aggccagtct ccacagctct tgatttatga ggtttccaac
      301 cgggcctctg gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg
      361 aaaatcagta gagtggaggc tgaggatgtt ggggtttatt actgcatgca agctctagag
      421 tttccattca ctttcggccc cgggaccaaa ctggatatca aacgag
//
LOCUS       KCVT01006930             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13543:15525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006930
VERSION     KCVT01006930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13543:15525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84455.1"
                     /translation="CLQTKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           96 a          119 c          116 g          100 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcagcag aaaccaggac aacctcctaa
      241 actcctggtt tatcaagcaa ccaataggga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg cccgatttca ccctcacaat taatcctgtg gaacctgacg atgctgctaa
      361 ttattactgt ctgcagacta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01006931             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17417:5272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006931
VERSION     KCVT01006931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17417:5272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..425
                     /note="immunoglobulin light chain variable region"
     V_region        106..425
     V_segment       106..389
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84456.1"
                     /translation="CLHYNSDPWTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>430
                     /gene="IGKC"
BASE COUNT          106 a          111 c          109 g          104 t
ORIGIN      
        1 acatggggga agttagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagc tcaggtgcca gatgtgacat ccagatgacc
      121 cagtctccat cttccctgtc tgcatctgta agagacagag tcaccttcgc ttacagggca
      181 agtcagggca ttacaactta tttaaattgg tgtcagcaga aatcaggaaa acctcctaag
      241 cgcctgatct gtgttgaata cagtttggaa agtggggtcc catcaaggtt cagtagcagt
      301 ggatctgggt caggtttcac tctcaccatc agcagcctgc agcctgaaga ttttacacct
      361 tattactgtc ttcattataa cagtgacccg tggacgttcg gccaggggac caaggtggaa
      421 ttcaagcgag
//
LOCUS       KCVT01006932             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9283:10300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006932
VERSION     KCVT01006932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9283:10300"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84457.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          116 c          106 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaagca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01006933             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22615:17683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006933
VERSION     KCVT01006933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22615:17683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84458.1"
                     /translation="CMQPLEFPWTF"
     J_segment       240..277
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           71 a           61 c           82 g           66 t
ORIGIN      
        1 acatgggggt ctagtcagag cctcttggat agtgaggatg gaaacaccta tttggaatgg
       61 tacctccaga agccaggcca gtctccacat ctcttgattt atgaggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      181 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaacctct agagtttccg
      241 tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01006934             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13327:14970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006934
VERSION     KCVT01006934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13327:14970"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..461
                     /note="immunoglobulin light chain variable region"
     V_region        128..461
     V_segment       128..423
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <401..>433
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84459.1"
                     /translation="CLQSKNSPWSF"
     J_segment       424..461
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        462..>464
                     /gene="IGKC"
BASE COUNT          107 a          124 c          127 g          106 t
ORIGIN      
        1 acatggggat ccttaaaggc agcttgtcag gggccctgag gagcagcctc tagttcagct
       61 ctcagaaatg gggtcctggg ctcctttcct gtggatcctc ctgctctgtg ctccaggctg
      121 cagtggggac attgtgctga cccagtctcc agcctctttg gccgtgtctc cagggcagag
      181 ggccaccatc acctgcagag ccagtgagag tgtcagtgcc tttggaataa gcctcattca
      241 ctggtatcaa cagaaaccag gacaacctcc taaactcctg atttaccaag caatcaataa
      301 ggagactggg gtcccagcca ggttcagcgg cagtgggtct gggaccgatt tcaccctcac
      361 aattaatcct gtggaacctg acgatggtgc agattattac tgtctgcaga gtaagaattc
      421 tccgtggtcg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006935             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:16388:7594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006935
VERSION     KCVT01006935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16388:7594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84460.1"
                     /translation="CQQHNEYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          119 c          105 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacagcat aatgaatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006936             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13170:10954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006936
VERSION     KCVT01006936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13170:10954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84461.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006937             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14960:6985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006937
VERSION     KCVT01006937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14960:6985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84462.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          122 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006938             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13587:3564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006938
VERSION     KCVT01006938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13587:3564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84463.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccagag ctcttgattt atgaggtttc caagcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggctt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006939             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23756:6683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006939
VERSION     KCVT01006939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23756:6683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84464.1"
                     /translation="CMQSLEFPWTS"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           91 a          118 c          124 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggggag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atgttgaaga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttggt ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttgggt tttatttctg catgcagagt ctggagtttc cttggacgtc cggccaaggg
      421 accaaggtgg aagtcaaacg ag
//
LOCUS       KCVT01006940             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:27051:7656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006940
VERSION     KCVT01006940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:27051:7656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84465.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatcaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcgga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggaa tttatttctg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006941             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15054:14816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006941
VERSION     KCVT01006941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15054:14816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84466.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          119 c          108 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtgggag acacagtcac catcacttgt cgggcaagtc
      181 aggtcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01006942             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:16230:12871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006942
VERSION     KCVT01006942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16230:12871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84467.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          122 c          116 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagcgtagc ctggtaccag cagaaacctg ggcaggctcc cagactcctc
      241 atgtatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006943             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20072:13937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006943
VERSION     KCVT01006943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20072:13937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84468.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          111 c          102 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacgt
      181 taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006944             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24525:11307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006944
VERSION     KCVT01006944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24525:11307"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84469.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attctgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta cttggaatgg tatttgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caagcgggcc tctggagtcc ccgacaggtt
      301 cagtggcagt gggtcaggca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatcactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01006945             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6924:18214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006945
VERSION     KCVT01006945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6924:18214"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..362
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84470.1"
                     /translation="CQQYDSDSLTF"
     J_segment       367..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT          100 a          111 c          105 g           91 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctaggac tcctgctgct
       61 ctgtctccca ggtgccaaat gtgacatcca gatgacccag tctccatcct ccctgtctgc
      121 atctgtagga gacagagtca ccatcacttg tcgggcgagt cagggcattc gcagttattt
      181 agcgtggtat cagcagaaac cagggaaagc cccgaagccc ttgatctatt acgcgtccac
      241 tttggaaagt ggggtcccat caagattcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agtatgacag
      361 tgactcgctc actttcggtg gagggaccaa ggtagagatc aaacgag
//
LOCUS       KCVT01006946             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10664:17973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006946
VERSION     KCVT01006946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10664:17973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84471.1"
                     /translation="CQQHGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          119 c          108 g           89 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag catggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01006947             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:4554:13415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006947
VERSION     KCVT01006947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4554:13415"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84472.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg ggtccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cattttctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01006948             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:15553:4112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006948
VERSION     KCVT01006948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15553:4112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    46..367
                     /note="immunoglobulin light chain variable region"
     V_region        46..367
     V_segment       46..330
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84473.1"
                     /translation="CQQHDDSPRTF"
     J_segment       332..367
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>370
                     /gene="IGKC"
BASE COUNT           96 a          100 c           94 g           80 t
ORIGIN      
        1 acatgggggg ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc
       61 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcacagcc
      121 agtcagggta ttaataactg gttggcctgg tatcaacaga aaccaggaaa agcccctaaa
      181 ctcctgatct atagggcatc caatttggac acaggggtcc catcgaggtt cggtggaagt
      241 ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca
      301 tattactgtc aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa
      361 atcaaacgag
//
LOCUS       KCVT01006949             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:13853:6350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006949
VERSION     KCVT01006949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13853:6350"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..231
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <209..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84474.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       241..271
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>278
                     /gene="IGKC"
BASE COUNT           74 a           67 c           72 g           65 t
ORIGIN      
        1 acatgggatc acttgtcggg caagtcagga cattggcaat tatttagcct ggtatcagca
       61 gaaaccaggg aaagccccta acctcctgat ctataaggcg tccagtttac aaagtggggt
      121 cccatcaagg ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct
      181 gcagcctgaa gattttgcag tttattactg tcaacagcgt aatagttacc cgtacatgtg
      241 cagttttggc ccggggacca aagtggagat ccgacgag
//
LOCUS       KCVT01006950             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20645:15402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006950
VERSION     KCVT01006950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20645:15402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84475.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcactcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006951             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16728:15272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006951
VERSION     KCVT01006951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16728:15272"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84476.1"
                     /translation="CQQGYYTPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          113 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcgtccc tgtctgcatc tgtaggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattagca gctggttagc ctggtatcag cagaaaccag ggaaagcccc tagactcctg
      241 atctataagg cgtccacttt ggcaagtggg gtcccatcaa ccttcagcgg cagtggatct
      301 gggacggatt acactctcac catcaacagg ctgcagcctg aagattttgc tacttattat
      361 tgtcaacagg gttactatac cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01006952             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13985:8925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006952
VERSION     KCVT01006952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13985:8925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84477.1"
                     /translation="CQQYDSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaactgggg tcccatcaag gttcagcggc agtggattgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01006953             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11316:9764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006953
VERSION     KCVT01006953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11316:9764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84478.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtatacatca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01006954             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:17075:6972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006954
VERSION     KCVT01006954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:17075:6972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84479.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          121 c          119 g          104 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcctg gatagtgagg atggaaacac ctatttgcac tggtacctga agaagccagg
      241 ccagtctcca cagctcttaa tttatgaagt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01006955             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16592:16881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006955
VERSION     KCVT01006955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16592:16881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84480.1"
                     /translation="CQQGYNPPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcagggtat
      181 tagcagctgg ttagcctggt atcagcagaa accagggaaa gcccctaaac tcctgatcta
      241 taagtcgtcc aatttggcaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 ggattacact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagggttac aatccccctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006956             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19420:19403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006956
VERSION     KCVT01006956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19420:19403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84481.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01006957             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:23618:16652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006957
VERSION     KCVT01006957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23618:16652"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84482.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          122 c          119 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattctgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atggtgaaga tggaaacacc tatttgcact ggtacctgaa gaggccaggc
      241 cagtctccac atctcttaat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01006958             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10318:9991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006958
VERSION     KCVT01006958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10318:9991"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84483.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          113 a          118 c          106 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gagccagtca
      181 cgatattaac aactggttgg cctggtatca acagaaacca gggaaagccc ctaaggtcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatca aggttcagtg gaagtggttc
      301 tgggacagat ttcactctca ccatcaacaa cctgcagcct gaagatatcg caacatatta
      361 ctgtcaacaa catgatgatt cccctcggac cttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01006959             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7088:2531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006959
VERSION     KCVT01006959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7088:2531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84484.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          111 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006960             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:8436:8062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006960
VERSION     KCVT01006960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8436:8062"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84485.1"
                     /translation="CMQGLEFPRTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          104 t
ORIGIN      
        1 atggggactg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag atctagtcag
      181 agtctcttgg atagtgcgga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactaaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaggt ctagagtttc ctcggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01006961             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:15650:3784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006961
VERSION     KCVT01006961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15650:3784"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    47..360
                     /note="immunoglobulin light chain variable region"
     V_region        47..360
     V_segment       47..322
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <300..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84486.1"
                     /translation="CMQALEFPWTF"
     J_segment       323..360
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>363
                     /gene="IGKC"
BASE COUNT           86 a           92 c          101 g           84 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgcccgtca
       61 cccttagaga gccggcctcc atctcctgca ggtctagtca gagcctcttg gatagtgagg
      121 atggaaacac ctatttggaa tggtacctac agaggccagg ccagtctcca cagctcttaa
      181 tttatgaggt ttcctaccgg gcctctggag tcccagacag gttcagtggc agtgggtcag
      241 acactgattt cacactgaaa atcagcagag tggaggctga ggatgttggg gtttattact
      301 gcatgcaagc tctagagttt ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      361 gag
//
LOCUS       KCVT01006962             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11799:15464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006962
VERSION     KCVT01006962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11799:15464"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84487.1"
                     /translation="CQQYDSFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          116 c          102 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccaggtgtga cattcagatg acccagtctc
      121 catcctccct gtcagcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatac aaatcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 gggcagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatagtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01006963             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11050:20528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006963
VERSION     KCVT01006963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11050:20528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84488.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gcttagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01006964             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19691:4766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006964
VERSION     KCVT01006964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19691:4766"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84489.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          122 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cacttttcct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacactt atttggactg gtacctacag aggccaggcc
      241 agactcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atcttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006965             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:14963:17488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006965
VERSION     KCVT01006965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14963:17488"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84490.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c          103 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaaga ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgag gattttgcga cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg ataccaaacg
      421 ag
//
LOCUS       KCVT01006966             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:24132:14355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006966
VERSION     KCVT01006966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24132:14355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84491.1"
                     /translation="CQHSYGTPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          105 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtaggacaa gtcagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcgtcc aatttgcaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ttcaccatca ccagcctgca acctgaagat gttgcaactc attactgtca
      361 gcatagttat ggtaccccgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01006967             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10981:4974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006967
VERSION     KCVT01006967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10981:4974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84492.1"
                     /translation="CQQYDSDPFTF"
     J_segment       390..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          103 a          116 c          116 g           93 t
ORIGIN      
        1 acatgggggg gggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca gtttggaaag tggggtccca tcaaggttca gcggcggtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacccgtt cactttcggt ggagggacca aggtagacat
      421 caaacgag
//
LOCUS       KCVT01006968             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14712:9052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006968
VERSION     KCVT01006968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14712:9052"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84493.1"
                     /translation="CQQGYTYLYSF"
     J_segment       382..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          115 c          106 g          101 t
ORIGIN      
        1 acatgggggg tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gttggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctga
      241 tctatagggc atccagtttg caaagtgggt ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ttgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01006969             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:22509:3244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006969
VERSION     KCVT01006969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22509:3244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84494.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>440
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaacgag
//
LOCUS       KCVT01006970             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9887:18183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006970
VERSION     KCVT01006970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9887:18183"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84495.1"
                     /translation="CQQGYGFPWTF"
     J_segment       384..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          118 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taatttaaat tggtatcagc agaaaccagg gaaagcccct aaactcctga
      241 tctctaaggc atccagtttg caaagtggga ttccctctcg gctcagcggc agtggatctg
      301 gggcggattt cactctcacc atcggcagcc tgcagcctga agattttgcc acttactact
      361 gtcaacaggg ttatggtttc ccatggacat tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01006971             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14625:15405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006971
VERSION     KCVT01006971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14625:15405"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84496.1"
                     /translation="CQQGYGLPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          120 c          107 g           95 t
ORIGIN      
        1 acatgggggg agtcagtccc agtcaggaca cagcatggac atgagggccc ccactcagct
       61 cctggggttc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctataggaga cagagtcacc atcacttgcc aggcgaatca
      181 ggacattaac aatattttag cctgctatca gcagaaaccg gggaaagccc ctaagctcct
      241 tatctatgag gcatccactt tacaaagtgg ggtcccatca cggttcagcg gcggtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcagcaa ggttatggtc tcccgctcac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01006972             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16134:8582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006972
VERSION     KCVT01006972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16134:8582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84497.1"
                     /translation="CLQYRSYPYNF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          110 a          111 c          106 g           97 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 gatattagca gttatttaaa ttggtttcag aagaaaccag ggaaagcccc taagctcctg
      241 atccaagctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cggtagatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt atagaagtta cccgtacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006973             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7331:19690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006973
VERSION     KCVT01006973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7331:19690"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84498.1"
                     /translation="CQQYDSDSLTF"
     J_segment       387..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          107 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctaggac tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgact
      181 caagacattc gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaggccc
      241 ttgatctatt acgcgtccac tttggaaagt ggagtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcaac aatatgacag tgactcgctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01006974             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11480:16232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006974
VERSION     KCVT01006974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11480:16232"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84499.1"
                     /translation="CQQYDNDPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          116 c          108 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctcac tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacaatga cccgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01006975             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21808:4988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006975
VERSION     KCVT01006975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21808:4988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84500.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          113 c          108 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcaggccat
      181 tagcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 tttcgcatct attttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt atagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006976             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:20072:14297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006976
VERSION     KCVT01006976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20072:14297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84501.1"
                     /translation="CQQDFGWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          122 c          122 g           91 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagactgttg gcagcgcctt agcctggtac cagcagaaac ctgggcagac
      241 tcacaaactc ctcgtttatg gtgcatccac cagggccacc ggcatcccag acaggttcag
      301 tggcagtggg tctggaacag agttcactct caccatcagt agtccggagc ctgaggatgt
      361 tggagtttat tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01006977             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:26666:10139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006977
VERSION     KCVT01006977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:26666:10139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84502.1"
                     /translation="CQQDYSWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          120 c          117 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tgtcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcatcttag cctggtacca ccagaaacct gggcaggctc ccaagtccct
      241 catctatggt gcaaccagta gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gcgtttatta
      361 ctgtcagcag gattatagct ggccactcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006978             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14790:11678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006978
VERSION     KCVT01006978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14790:11678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84503.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgatgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006979             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4773:17818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006979
VERSION     KCVT01006979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4773:17818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..405
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84504.1"
                     /translation="CQQYNSDPYTF"
     J_segment       406..443
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          108 a          119 c          121 g           98 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag gtgacccagt ctccgtcctc cctgtctgca tctgtaggag acagagtcac
      181 catcacttgt cgggcgagtc agggcgttag aagttattta gcgtggtatc agctgagacc
      241 agggaaagcc ccgaaggcct taatctatta cgcgaccatt ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaggatttt gcaacttatt tctgtcaaca gtataacagt gacccgtaca cttttggcca
      421 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01006980             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:13968:4476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006980
VERSION     KCVT01006980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13968:4476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..372
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84505.1"
                     /translation="CQQYYSFPITF"
     J_segment       386..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT           99 a          114 c          113 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggccac agcatggaca tgagggtccc cgctcagttc
       61 ctggggctcc tgctgctctg gatcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac aaagtcacca tcacttgccg agccagtcag
      181 ggtattaaca cctggttaat ttggtatcag cagaaaccag ggaaagcccc taaggccctg
      241 atctataagg catccagttt gcaaggtggg gtcccttcca ggttcagcgg cagtggatct
      301 ggggcagact tcactctcac catcaccaac ctgcagcctg aagattttgg aatttattac
      361 tgtcaacaat attatagttt tccgatcact ttcggtgggg ggaccaaggt ggagatcagg
      421 cgag
//
LOCUS       KCVT01006981             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:3288:13678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006981
VERSION     KCVT01006981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3288:13678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84506.1"
                     /translation="CMQGIDYPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          102 a          118 c          117 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gtcagtcacc cctggagagc cggcctccat ctcctgcagc tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacatct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gcccttgatt tataaggttt ccacccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaaggta tagactatcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01006982             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:17150:19060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006982
VERSION     KCVT01006982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:17150:19060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84507.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           94 a          120 c          125 g          105 t
ORIGIN      
        1 acatgggggc tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagcgg ggacattgtg atgacccaga
      121 ctccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctacttgga atggtatttc cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaagcg ggcctctgga gtcgcagaca
      301 ggttcagtgg cagtgggtca ggcactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatcac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01006983             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13651:13134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006983
VERSION     KCVT01006983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13651:13134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84508.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctttgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006984             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11948:13016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006984
VERSION     KCVT01006984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11948:13016"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84509.1"
                     /translation="CQHSFRTPYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           97 t
ORIGIN      
        1 acatggggag gagtcagtct cagtcaggac acagcatgga catgagggcc tctgctcagc
       61 tcctagggct cctgctgctc tggctcccag gcgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcaa tgtcacttgc agggctagtg
      181 agagcgttag caccaaatta cattggtatc agcagaaacc agggaaagcc cctaagctcc
      241 tgatctttgc tgcgtccact ttgcaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctggaacaga tttcactctc accatcagca gcctgcagcc tgaagatgtc gcaacttttt
      361 actgtcagca tagttttcgt accccgtaca gttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01006985             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:11939:24736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006985
VERSION     KCVT01006985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11939:24736"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84510.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcgt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcaag tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccacacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01006986             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19054:9823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006986
VERSION     KCVT01006986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19054:9823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84511.1"
                     /translation="CMQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          117 c          122 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttatttctgc atgcaaagtc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006987             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19054:9869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006987
VERSION     KCVT01006987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19054:9869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84512.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga aatcaaacga g
//
LOCUS       KCVT01006988             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22214:5462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006988
VERSION     KCVT01006988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22214:5462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..359
                     /note="immunoglobulin light chain variable region"
     V_region        82..359
     V_segment       82..320
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84513.1"
                     /translation="CQQYNSDLFTF"
     J_segment       324..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           92 a           95 c           97 g           78 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggagacag agtcaccatc acttgtcggg cgagtcagga
      121 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      181 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      301 tcaacagtat aacagtgacc tgttcacttt cggtggaggg accaaggtgg agatcaaacg
      361 ag
//
LOCUS       KCVT01006989             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:8339:16537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006989
VERSION     KCVT01006989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8339:16537"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84514.1"
                     /translation="CLQYKSYPLTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>420
                     /gene="IGKC"
BASE COUNT          105 a          112 c          105 g           98 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatcac ttgccgggca agtcagggta
      181 ttagcactta tttaaattgg tttcagcaga aaccagggaa agcccctaga ctcctgatct
      241 atgctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcagct tatcactgtc
      361 tacagtataa aagttaccct ctcactttcg gcgaagggac caaggtggag atcaaaagag
//
LOCUS       KCVT01006990             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17489:3078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006990
VERSION     KCVT01006990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17489:3078"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84515.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atttattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01006991             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8857:24560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006991
VERSION     KCVT01006991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8857:24560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84516.1"
                     /translation="CLQSKNSPWSF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          101 a          116 c          115 g           99 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggctgcag tggggacatt gtgctgaccc agtctccagc
      121 ctctttggcc gtgtctccag ggcagagggc caccatcacc tgcagaacca gtgagagtgt
      181 cagtgccttt ggaataagcc tcattcactg gtatcaacag aaaccaggac aacctcctaa
      241 actcctgatt taccaagcaa tcaataagga gactggggtc ccagccaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaacctgacg atggtgcaga
      361 ttattactgt ctgcagagta agaattctcc gtggtcgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01006992             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:15998:20110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006992
VERSION     KCVT01006992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:15998:20110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84517.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggcc cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01006993             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23555:13950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006993
VERSION     KCVT01006993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23555:13950"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..234
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84518.1"
                     /translation="CQQYNSLPFTF"
     J_segment       235..272
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>275
                     /gene="IGKC"
BASE COUNT           80 a           66 c           63 g           66 t
ORIGIN      
        1 acatgggacc atcacttgcc gggcaagtca gggcattagc aattatttaa attggtatca
       61 gcagaaaccg gggaaagccc ctaagcacct gatctattat tcaaaccgtt tggaaagtgg
      121 ggtcccatca aggttcagcg gcagtggatc tgggacagaa ttcagtctca ccatcagcag
      181 cctgcaacct gaagattttg caacttatta ctgtcaacag tataatagtt tgccattcac
      241 tttcggcccc gggaccaaac tggatatcaa acgag
//
LOCUS       KCVT01006994             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:19662:8443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006994
VERSION     KCVT01006994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19662:8443"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..428
                     /note="immunoglobulin light chain variable region"
     V_region        89..428
     V_segment       89..390
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84519.1"
                     /translation="CMQALEFPLTF"
     J_segment       391..428
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           95 a          116 c          118 g          102 t
ORIGIN      
        1 atgggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc tgggactgct
       61 aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc cactctccct
      121 gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga gcctcctgga
      181 tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc agtctccaca
      241 ggtcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt tcagtggcag
      301 tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg atgttggggt
      361 ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga ccaaggtgga
      421 gatcaaacga g
//
LOCUS       KCVT01006995             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:20352:14451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006995
VERSION     KCVT01006995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20352:14451"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84520.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          116 c          122 g          108 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagt
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acttgcagaa ggcaggccag
      241 tctccacagc tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagccac tgatttcaaa ctgaacatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01006996             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15445:6968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006996
VERSION     KCVT01006996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15445:6968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84521.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          126 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga caaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccagca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01006997             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:7982:18901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006997
VERSION     KCVT01006997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7982:18901"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84522.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          103 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgatcta
      241 tagggcatcc actttgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacctgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01006998             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:17829:15570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006998
VERSION     KCVT01006998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17829:15570"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84523.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctatat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01006999             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20497:8692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01006999
VERSION     KCVT01006999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20497:8692"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    140..479
                     /note="immunoglobulin light chain variable region"
     V_region        140..479
     V_segment       140..442
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <419..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84524.1"
                     /translation="CMQALEFPLTF"
     J_segment       443..479
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>482
                     /gene="IGKC"
BASE COUNT          107 a          128 c          131 g          116 t
ORIGIN      
        1 acatgggggg agtgtgagat aaaagctcag cactaacctt gccttgactg atcacgactc
       61 ctcaggtcac cttctcacaa tgaggctccc tgctcagctc ctgggactgc taatgctctg
      121 gctccctgga tccagtgggg acattgtgat gacccagact ccagtctccc tgcccgtcac
      181 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga
      241 tggaaacacc tatttggaat ggttcctgca gaagccaggc cagtctccac agctcttgat
      301 ttatgacgtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      361 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      421 catgcaagct ctagagtttc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      481 ag
//
LOCUS       KCVT01007000             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16698:15391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007000
VERSION     KCVT01007000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16698:15391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84525.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           96 a          117 c          105 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccagggggcc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007001             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:18066:14915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007001
VERSION     KCVT01007001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18066:14915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84526.1"
                     /translation="CQQGYTYLYSF"
     J_segment       378..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          104 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcac ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgttg gagacacagt caccatcact tgccaggcga gtcaagccat
      181 tgccaataat ttaaattggt atcagcagaa accaggaaaa gcccctaaag tcctgatcta
      241 tagggcatcc agtttgcaaa gtgggtttcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat acttacttgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007002             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18797:4456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007002
VERSION     KCVT01007002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18797:4456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84527.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          120 c          105 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcaac tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007003             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10997:12134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007003
VERSION     KCVT01007003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10997:12134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84528.1"
                     /translation="CQQHDNAPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          109 a          118 c          117 g           84 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcccgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcagagtatt aacgactggt tggcctggta tcaacagaga ccagggaagg cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcagcatcag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcag cagcatgaca atgccccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01007004             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15303:7270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007004
VERSION     KCVT01007004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15303:7270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..391
                     /note="immunoglobulin light chain variable region"
     V_region        70..391
     V_segment       70..354
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84529.1"
                     /translation="CLQYKSFPLTF"
     J_segment       355..391
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>394
                     /gene="IGKC"
BASE COUNT           93 a          101 c           97 g          103 t
ORIGIN      
        1 acatgggaca tgagggcccc cgctcatctc ctagggctcc tgctgctctg gctcccaggt
       61 gccagatgtg acatccagat gactcagtct ccatcttccc tgtctgcatc tgtgggagac
      121 actgtcacca tcacttgccg ggcaagtcag gatattaaca gttatttaaa ttggtttcag
      181 ctgaaaccag ggaaagcccc aaaggtcctg atctatgctg catccagttt ggaaagtggg
      241 gtcccgtcta ggttcagcgg cagtggatct gggacagaat tcactctcac catcagtagc
      301 ctgcagcctg aagattttgc aacttattat tgtctacagt ataaaagttt tcctctcact
      361 ttcggtggag ggaccaaggt ggatatcaaa cgag
//
LOCUS       KCVT01007005             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:26004:5404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007005
VERSION     KCVT01007005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:26004:5404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84530.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttatgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007006             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14910:18169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007006
VERSION     KCVT01007006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14910:18169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84531.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttcca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007007             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13324:12796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007007
VERSION     KCVT01007007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13324:12796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84532.1"
                     /translation="CQQHDNSPPTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggca gtctcagaca gggcacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctcctt
      121 cctccctgtc tgcatctata ggcgacagag tcaccatcac ttgcagagcc agtcagggta
      181 ttagcgactg gttggcctgg tatcaacaga aaccagggaa agcccctaaa ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc aggctgaaga tttcgcaaca tatttctgtc
      361 aacagcatga taattcccct cccactttcg gtggagggac taaggtggag atcaaacgag
//
LOCUS       KCVT01007008             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14857:18498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007008
VERSION     KCVT01007008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14857:18498"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..375
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84533.1"
                     /translation="CQQVYHNAFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          112 c          105 g          104 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgtcttgtct gcatctgtgg gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagtaat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tggtgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaggat tctgcaactt atttctgtca
      361 acaggtttat cataatgcat tcactttcgg ccccgggacc aaattggata tcaaacgag
//
LOCUS       KCVT01007009             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7138:2554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007009
VERSION     KCVT01007009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7138:2554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..377
                     /note="immunoglobulin light chain variable region"
     V_region        64..377
     V_segment       64..342
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84534.1"
                     /translation="CQQGHSYPWTF"
     J_segment       348..377
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>388
                     /gene="IGKC"
BASE COUNT           88 a          109 c          101 g           90 t
ORIGIN      
        1 acatgggggg tccccgctca gctccttggg ctcctgctgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgacgca gtctccatcc tccctgtccg catctgtagg agacacagtc
      121 acgatcactt gccagtcgag tctaggcatt ggcaaatttt taaattggta tcagcagaaa
      181 ccagggaaag cccccaaact cctgatctat agggcatcca gtttgcaaac tgggattccc
      241 tctcggttca gcggcagtgg atctgggacg gatttcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgccgctta ttactgtcaa cagggtcata gttacccgtg gacgttcggc
      361 caagggacca aggtggagat gaaacgag
//
LOCUS       KCVT01007010             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18850:4188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007010
VERSION     KCVT01007010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18850:4188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84535.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaattt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01007011             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12717:22011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007011
VERSION     KCVT01007011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12717:22011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84536.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          117 g          111 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggtgtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc ttgagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007012             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23739:15394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007012
VERSION     KCVT01007012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23739:15394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84537.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007013             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16796:6538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007013
VERSION     KCVT01007013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16796:6538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84538.1"
                     /translation="CQQYNNLPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          111 c          103 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggcccc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat aatttacctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007014             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17493:9716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007014
VERSION     KCVT01007014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17493:9716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84539.1"
                     /translation="CLQESNWSYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tagtaccgga gaaatagtgg tgacacagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcaaa agcaggttag cctggtacca gcagaaacct gggcaagctc ccaggctcct
      241 catgtatgat gcgtccagca gggccactgg catcccagac aggttcactg gcagcgggtc
      301 tgggccagag ttcactctca ccatcagcag cctggagcct gaagatgttg cggtttattt
      361 ctgtcttcag gagagtaact ggtcgtacag ctttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007015             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7527:2527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007015
VERSION     KCVT01007015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7527:2527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84540.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catacgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007016             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6860:16318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007016
VERSION     KCVT01007016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6860:16318"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84541.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttt ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007017             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9364:5983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007017
VERSION     KCVT01007017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9364:5983"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..407
                     /note="immunoglobulin light chain variable region"
     V_region        89..407
     V_segment       89..373
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84542.1"
                     /translation="CQQYNRSPRTF"
     J_segment       375..407
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>413
                     /gene="IGKC"
BASE COUNT          103 a          111 c          106 g           93 t
ORIGIN      
        1 acatgggcag tcaggacaca gcatggacat gagggtcccc gctcagctcc tggggctcct
       61 gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc catcctccct
      121 gtctgcatct gtaggagaca gagtcaccat cacttgccgg acaagtcagg gcattagtca
      181 atatttaaat tggtatcagc agaaaccggg gaaagcccct aggctcctca tctattatgt
      241 aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact gtcagcagta
      361 taatcgttca cctcggacgt tcggccaagg gaccaaggtg gaaatcagac gag
//
LOCUS       KCVT01007018             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22243:16051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007018
VERSION     KCVT01007018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22243:16051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..307
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84543.1"
                     /translation="CQQGDSYPRTF"
     J_segment       309..344
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>347
                     /gene="IGKC"
BASE COUNT           91 a           88 c           88 g           80 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacattca gatgtcccag tctccttcct ccctgtctgc
       61 atctgtggga gacagagtca ccatcacttg ccgggcaagt caggacatta gagattattt
      121 aaattggtat cagcagcaac cggggaaagc ccctaaactc ctgatgtatt atgcaaacag
      181 tctggcaagt ggagtcccat caaggttcag cggcagtgga tctgggacag aattcagtct
      241 caccatcagc agcctgcagc ctgaagattt tgcaacttat tactgtcaac agggtgacag
      301 ttatcctcgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01007019             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15760:10259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007019
VERSION     KCVT01007019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15760:10259"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84544.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           88 a          123 c          121 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007020             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8220:17918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007020
VERSION     KCVT01007020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8220:17918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84545.1"
                     /translation="CQQYNYLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          112 c          103 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaacc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagccttca acctgaggat tttgcaactt attactgtca
      361 acagtataat tatttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01007021             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:21247:14752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007021
VERSION     KCVT01007021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21247:14752"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84546.1"
                     /translation="CQQGYSYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          116 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 cctcctccct gtccgcatct gtaggagacg cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taatttaaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataagac atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac ccgtggacgt tcggccaagg ggccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007022             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24824:17371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007022
VERSION     KCVT01007022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24824:17371"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84547.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007023             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17046:20028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007023
VERSION     KCVT01007023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17046:20028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84548.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007024             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23594:16561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007024
VERSION     KCVT01007024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23594:16561"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84549.1"
                     /translation="CLQFKTYPNSF"
     J_segment       384..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           96 a          118 c          106 g          102 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg taggagacac tgtcaccatc tcttgccggg caagtcaggg
      181 tattagcagt tctttaagtt ggtttcagca gaaaccaggg aaagcccctc agctcctcat
      241 ctatgctgca tccagtttgg ccggtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc tctctcacca tcaccagcct gcagcctgaa gattttgcaa cttatttctg
      361 tctgcagttt aaaacttacc cgaacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007025             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:6590:9497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007025
VERSION     KCVT01007025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6590:9497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84550.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca ggctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007026             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:21719:14244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007026
VERSION     KCVT01007026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21719:14244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84551.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          113 g           90 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcagca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttactac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007027             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13780:11395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007027
VERSION     KCVT01007027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13780:11395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84552.1"
                     /translation="CQQYNSDLFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          111 c          109 g           95 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct caactcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatttgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc aattttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgacctg ttcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007028             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14700:5918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007028
VERSION     KCVT01007028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14700:5918"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84553.1"
                     /translation="CQQYDSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          105 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccggccaa gtcaggacat
      181 tagtcattat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatctt
      241 ttatgcaaac cgtttgggaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcgactt attattgtca
      361 gcagtatgat agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007029             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14889:12170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007029
VERSION     KCVT01007029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14889:12170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84554.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          108 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ccctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007030             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14442:4142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007030
VERSION     KCVT01007030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14442:4142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84555.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcgga
      181 gcctcttgga tagtgacgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 ggtctccaca ggtcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacagga
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggcat ttattactgc atgcaaagtc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007031             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21633:12340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007031
VERSION     KCVT01007031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21633:12340"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84556.1"
                     /translation="CLQYKSFPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          113 c          100 g          101 t
ORIGIN      
        1 acatgggagt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtggc atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg tgggagacac tgtcaccatc acttgccgga caagtcaagg
      181 tattaccaat tatttacatt ggtttcagca gaaaccaggg aaagccccta agctcctgat
      241 ctatgaaaca tccagtttgg taagtggggt cccatcaagg ttcagcggca gtgcatctgg
      301 gacagaattc actctcacca tcagcagcct acagcctgaa gattttgcat cttattactg
      361 tctacagtat aaaagtttcc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007032             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16583:10315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007032
VERSION     KCVT01007032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16583:10315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84557.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc actgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtatacatca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctcatcgg gactctgggg tcccagacag attcagcggc
      301 agtgggacag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01007033             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6476:9745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007033
VERSION     KCVT01007033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6476:9745"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84558.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT          100 a          118 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttagagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttaattt atgaggtttc ctaccgggcc tctggagtcc cagagaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agaatttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007034             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25399:7780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007034
VERSION     KCVT01007034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25399:7780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..379
                     /note="immunoglobulin light chain variable region"
     V_region        106..379
     V_segment       106..341
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84559.1"
                     /translation="CQQYNSDPFTF"
     J_segment       342..379
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>382
                     /gene="IGKC"
BASE COUNT           99 a          105 c           94 g           84 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 acttgtcggg cgagtcagga cataagaagt tatttagcgt ggtatcagca gaaaccaggc
      181 aaagccccga agcccttgat ctattacgca tccgttttgg aaagtggggt cccatcaagg
      241 ttcagtggca gtggatctgg gacagaattc actctcacca tcagcagtct gcagcctgag
      301 gattttgcaa cttattactg tcaacagtat aacagtgacc cattcacttt cggccccggg
      361 accaaactgg ataccaaacg ag
//
LOCUS       KCVT01007035             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14039:3313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007035
VERSION     KCVT01007035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14039:3313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84560.1"
                     /translation="CQQGYGFPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          119 c          103 g          102 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcgcga tcacttgcct ggcgagtcaa
      181 ggcattgaca ataatttaaa ttggtatcag cagaaaccag ggaaagcccc taaactcctg
      241 atctatacgg catccaattt acatggtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcaacagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatggttt tccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01007036             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8946:4411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007036
VERSION     KCVT01007036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8946:4411"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    45..384
                     /note="immunoglobulin light chain variable region"
     V_region        45..384
     V_segment       45..347
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84561.1"
                     /translation="CIQSLEFPWTF"
     J_segment       348..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           85 a           98 c          107 g           97 t
ORIGIN      
        1 acatgggggg actgctaatg ctctggctcc ctggatccac tggggacatt gtgatgaccc
       61 agactccact ctccctgccc gtcacccttg gagagccggc ctccttctcc tgtaggtcta
      121 gtcacagcct cttggatagt gaggatggaa atatccattt ggattggtat ctgcagaagc
      181 caggccagtc tccacacctc ttgatttatg aggtttccaa ccgggcctct ggagtcccag
      241 acaggtttag tggcagtggg tcagacactg atttcacact gaaaatcagc agggtggagg
      301 ctgaggatgt tggggtttac tactgcatac aatctcttga gtttccttgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01007037             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14964:14799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007037
VERSION     KCVT01007037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14964:14799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84562.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagaac cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007038             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:10844:12181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007038
VERSION     KCVT01007038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10844:12181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84563.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          120 c          116 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccacc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007039             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:26907:6445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007039
VERSION     KCVT01007039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:26907:6445"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84564.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccaccaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01007040             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22113:14224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007040
VERSION     KCVT01007040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22113:14224"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84565.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctgaggatat
      181 tcgcagttac ttggcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007041             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10366:19994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007041
VERSION     KCVT01007041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10366:19994"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84566.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tcgagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007042             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18801:12137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007042
VERSION     KCVT01007042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18801:12137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..374
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84567.1"
                     /translation="CQQYYSFPITF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          101 a          113 c          114 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagt
       61 tcctggggct cctgctgctc tggatcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtgggag acaaagtcac catcacttgc cgagccagtc
      181 agggtattaa cacctggtta atttggtatc agcagaaacc agggaaagcc cctaaggccc
      241 tgatctataa ggcatccagt ttgcaaggtg gggtcccttc caggttcagc ggcagtggat
      301 ctggggcaga cttcactctc accatcacca acctgcagcc tgaagatttt ggaatttatt
      361 actgtcaaca atattatagt tttccgatca ctttcggtgg ggggaccaag gtggagatca
      421 ggcgag
//
LOCUS       KCVT01007043             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18806:12523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007043
VERSION     KCVT01007043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18806:12523"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84568.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagt ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007044             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20426:22663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007044
VERSION     KCVT01007044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20426:22663"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84569.1"
                     /translation="CLQYKSFPYTF"
     J_segment       391..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          117 c          100 g           98 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtgggagac actgtcacca tcacttgccg gacaagtcaa
      181 ggtattacca attatttaca ttggtttcag cagaaaccag ggagagcccc taagctcctg
      241 atctatgaaa catccagttt gacaagtggg gtcccatcaa ggttcagcgg cagtgcatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaagttt cccgtacacc tttggccagg ggaccaaact ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007045             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9508:6882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007045
VERSION     KCVT01007045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9508:6882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84570.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01007046             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:14028:13432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007046
VERSION     KCVT01007046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14028:13432"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84571.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctac agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007047             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:27479:18073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007047
VERSION     KCVT01007047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:27479:18073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84572.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007048             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4578:6609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007048
VERSION     KCVT01007048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4578:6609"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84573.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          125 c          112 g           83 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga catagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc agaaacctgg gcaggctccc agactcctca
      241 tctatggtgc gtccaacagg gccactggca tcccagacag gttcagtggc agaaatctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgca gatgttgcac tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggaggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007049             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19859:16266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007049
VERSION     KCVT01007049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19859:16266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84574.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          118 c          123 g          108 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca ctcttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttcctaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaag atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007050             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6224:17988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007050
VERSION     KCVT01007050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6224:17988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84575.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          108 c          105 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagatat ttaaattggt atcagcagaa acccgggaaa gcccctaaat tcctgatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attattgtca
      361 acagtataat agtttaccgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007051             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9254:16839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007051
VERSION     KCVT01007051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9254:16839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84576.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007052             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17702:12295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007052
VERSION     KCVT01007052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17702:12295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..435
                     /note="immunoglobulin light chain variable region"
     V_region        100..435
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84577.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>442
                     /gene="IGKC"
BASE COUNT           95 a          123 c          120 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgta tccagtggtg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgcgga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggctcaga cactgatttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccagggg
      421 accaaggtgg aaatcgaacg ag
//
LOCUS       KCVT01007053             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21303:15820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007053
VERSION     KCVT01007053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21303:15820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..372
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84578.1"
                     /translation="CQQGYNYPYSF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          101 a          113 c          107 g          100 t
ORIGIN      
        1 acatgggggc agtctcagtc aggacacagc atggacatga gggtccccgc tcagctcctt
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatggc gcagtctcca
      121 tcctccctgt ccgcatctat aggagacaca gtcacgatca cttgccaggc gagtcaaggc
      181 attggcaatt atttatattg gtatcagcag aaaccaggga aagcccctaa actcctgatc
      241 tataaggcat ccagtttgca aaatgggttt ccctctcgct tcagcggcag tggatctggg
      301 acggatttca atctcagtat cagcagcctg cagcctgacg attttgccgc ttattactgt
      361 caacagggtt ataattaccc gtacagtttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007054             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15596:8801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007054
VERSION     KCVT01007054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15596:8801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84579.1"
                     /translation="CQQYNSDPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          114 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagca gttatttagc gtggtatcag cagagaccag ggaaagcccc gaagcccttg
      241 atttattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aggattttgc aacttattac
      361 tgtcagcagt ataacagtga ccctctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007055             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19517:5578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007055
VERSION     KCVT01007055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19517:5578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84580.1"
                     /translation="CQQYNSDPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          114 c          108 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc gggcgagtca
      181 gggcattaga agttatttag cgtggtatca gcagaaacca ggaaaagccc cgaaggcctt
      241 gatctattac gcatccattt tagaaagtgc ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagtct gacgattttg caacttatta
      361 ctgtcaacag tataacagtg acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007056             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8489:9631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007056
VERSION     KCVT01007056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8489:9631"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84581.1"
                     /translation="CQQYNSLPRTF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>420
                     /gene="IGKC"
BASE COUNT          108 a          110 c          108 g           94 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagtcaata tttaaattgg tatcagcaga aaccggggaa agcccctaag gtcctcatct
      241 attatgtaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tattactgtc
      361 aacagtataa tagtttacct cggacgttcg gccaagggac caaggtggaa atcagacgag
//
LOCUS       KCVT01007057             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14195:6256
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007057
VERSION     KCVT01007057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14195:6256"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84582.1"
                     /translation="CLQFKTYPNSF"
     J_segment       387..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           97 a          118 c          107 g          103 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atctcttgcc gggcaagtca
      181 gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc ctcagctcct
      241 catctatgct gcatccagtt tggccggtgg ggtcccatca aggttcagcg gcattggatc
      301 tgggacagaa ttctctctca ccatcaccag cctgcagcct gaagattttg caacttattt
      361 ctgtctgcag tttaaaactt acccgaacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007058             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12867:11829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007058
VERSION     KCVT01007058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12867:11829"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84583.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          125 c          112 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcttgga cagtgaggat gaaaacacgt atttggaatg gtacgtgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttcg cactgaacat caacagagtg gaggctgagg
      361 atcttggaat ttattactgc atgcaagctc tagaatttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007059             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:19502:20379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007059
VERSION     KCVT01007059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19502:20379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..291
                     /note="immunoglobulin light chain variable region"
     V_region        5..291
     V_segment       5..254
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <231..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84584.1"
                     /translation="CMQAREFPLTF"
     J_segment       255..291
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>294
                     /gene="IGKC"
BASE COUNT           70 a           66 c           86 g           72 t
ORIGIN      
        1 acatgggctc catctcctgc atgtctagtc agagcctctt ggatagtgag gatggaaaca
       61 cctatgtgga atggtacctg cagaagccag gccagtctcc acagctcttg atttatgagg
      121 tttcctaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt
      181 tcacactgaa aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaag
      241 ctcgagagtt tcctctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007060             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16749:14987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007060
VERSION     KCVT01007060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16749:14987"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..379
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84585.1"
                     /translation="CYQHSRGWAF"
     J_segment       380..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           98 a          122 c          115 g           83 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaaa ttatattgac acagtctcca
      121 gccaccctgt ctttggcacc aggggaaaga gccactctct cctgcagggc cagtgagaat
      181 gttggcagct acttagcctg gtaccagcag aaccctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccagcagggc cactgacatc ccagacaggt tcagtggcag tgggtctcgg
      301 acagagttca ccctcaccat cagcagtctg gagcctgaag atgttggagt ctattactgc
      361 tatcaacata gcagggggtg ggcgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01007061             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7349:12049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007061
VERSION     KCVT01007061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7349:12049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84586.1"
                     /translation="CQQYDSDSLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           95 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gactcaggac
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ctactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007062             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18330:16902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007062
VERSION     KCVT01007062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18330:16902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..393
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84587.1"
                     /translation="CLQSKNSPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          103 a          115 c          116 g          100 t
ORIGIN      
        1 acatgggggg gagcagcctc tagttcagct ctcagaaatg gggtcctggg ctcctttcct
       61 gtggatcctc ctgctctgtg ctccaggctg caatggggac attgtgctga cccagtctcc
      121 agcctctttg gccgtgtctc cagggcagag ggccaccatc gtctgcagag ccagtgagag
      181 tgtcaatgtc tttggaataa acctcattca ctggtatcag cagaaaccag gacaacctcc
      241 taaacccctg atttaccaag catccaataa agaaactggg gtcccagcca ggttcagcgg
      301 cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaagctg acgatgctgc
      361 agattattac tgtctgcaga gtaagaattc tccgtggacg tttggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01007063             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12325:11996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007063
VERSION     KCVT01007063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12325:11996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84588.1"
                     /translation="CQQHDNFPYIF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          116 c          103 g           93 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcaaca
      181 tattagcgac tggttggcct ggtatcaaca gaaaccaggg aaagccccta agctcctgat
      241 ctatcgggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagctt tcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gataatttcc cgtacatttt tgaccagggg accaaactgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007064             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20545:19410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007064
VERSION     KCVT01007064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20545:19410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84589.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          125 c          113 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01007065             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15033:10232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007065
VERSION     KCVT01007065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15033:10232"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84590.1"
                     /translation="CQQHNGYPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          119 c          105 g           90 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattacgaat gatttagcct ggtatcaaca gaaaccaggt aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattattg
      361 tcaacaacat aatggatacc ctccgacgtt cggccaaggg accagggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01007066             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21090:15457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007066
VERSION     KCVT01007066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21090:15457"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84591.1"
                     /translation="CLQYKSYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          104 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 tagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgcttcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atcactgtct
      361 gcagtataaa agttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01007067             291 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:2967:14176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007067
VERSION     KCVT01007067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 291)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:2967:14176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    144..288
                     /note="immunoglobulin light chain variable region"
     V_region        144..288
     V_segment       144..251
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <228..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84592.1"
                     /translation="CMQALEFPLTF"
     J_segment       252..288
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>291
                     /gene="IGKC"
BASE COUNT           71 a           69 c           86 g           65 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccaggaga
      121 gtgtcacaga gcaggacagc aaggacaggt tcagtggcag tgggtcagac actgatttca
      181 cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaagctc
      241 tagaatttcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007068             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11910:15846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007068
VERSION     KCVT01007068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11910:15846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..417
                     /note="immunoglobulin light chain variable region"
     V_region        98..417
     V_segment       98..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84593.1"
                     /translation="CLQYKSFPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          112 c          101 g          100 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtggcat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccatcac ttgccggaca agtcaaggta
      181 ttaccaatta tttacattgg tttcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atgaaacatc cagtttggta agtggggtcc catcaaggtt cagcggcagt gcatctggga
      301 cagaattcac tctcaccatc agcagcctac agcctgaaga ttttgcatct tattactgtc
      361 tacagtataa aagtttcccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01007069             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17632:17982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007069
VERSION     KCVT01007069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17632:17982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..362
                     /note="immunoglobulin light chain variable region"
     V_region        85..362
     V_segment       85..315
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <302..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84594.1"
                     /translation="CQQHNNYSPTF"
     J_segment       328..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           94 a           99 c           94 g           78 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggaga cacagtcacc atcacttgtc gggcaagtca
      121 gggcattagc aatgatttag tctggtatca gctgaaacca gggaaagccc cgaagcccct
      181 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      241 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      301 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01007070             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16498:13755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007070
VERSION     KCVT01007070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16498:13755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84595.1"
                     /translation="CYQYTGGYTF"
     J_segment       382..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           92 a          127 c          111 g           88 t
ORIGIN      
        1 acatgggggc tgctaggtta gtacccagag ggaaccatgg aagccccagc tcggcttctc
       61 tgccttctgc tactctggct cccaggtacc accggacaag ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc aggggagaga gccactctct cctgcagggc cagtcagagt
      181 gttagtactt acttagcctg gtaccagcag aaacctgggc aggctcccag gctcctcatc
      241 cacagtgcgt ccagcagggc cactggcatc ccagacaggt tcagtggcag cgggtctggg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttggagt ttatcactgc
      361 tatcagtata ccggcggata cactttcggc cccgggacca aactggatat caaacgag
//
LOCUS       KCVT01007071             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:6938:9419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007071
VERSION     KCVT01007071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6938:9419"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84596.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          112 c          104 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag ggtcaccatc acttgccggg caagtcagga
      181 cgttaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007072             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18916:5647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007072
VERSION     KCVT01007072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18916:5647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84597.1"
                     /translation="CLQGYTIPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          112 c          107 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagtggttc tgactcagct
       61 cctggggctc cttctgctct ggctcccagg tcccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc ggacaagtca
      181 gggcattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatccatgct gtatccagtt tggaaagtgg ggccccatca aggttcagcg gcagtggatc
      301 tgaaacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag ggttatacta tcccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007073             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:5447:8375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007073
VERSION     KCVT01007073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5447:8375"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84598.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007074             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14264:13023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007074
VERSION     KCVT01007074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14264:13023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84599.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          124 g          103 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007075             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:11234:14554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007075
VERSION     KCVT01007075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11234:14554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84600.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cggtggggac attgtgatga cccaggctcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaactct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007076             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10718:11147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007076
VERSION     KCVT01007076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10718:11147"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84601.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          118 c          111 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag
      181 tcaggatatt aacacctggt tggcctggta tcaacagaag ccagggaaag cccctaaggt
      241 cctgatctat aggacatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcaa cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01007077             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11320:6179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007077
VERSION     KCVT01007077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11320:6179"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..237
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84602.1"
                     /translation="CQQYNGYPPTF"
     J_segment       250..284
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           82 a           72 c           72 g           61 t
ORIGIN      
        1 acatggggga gacacagtca ccatcacttg tcgggcaagt caggacatta ccaatgattt
       61 agcctggtat cagcagaaac cagggaaagc cccgaagccc ctgatctatt acgcatccaa
      121 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag atttcactct
      181 caccatcagc agcctgcagc ctgaagattt tgcaacttat tattgtcaac agtataatgg
      241 ataccctccg acgttcggcc aagggaccag ggtggaaatc aaacgag
//
LOCUS       KCVT01007078             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18293:15103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007078
VERSION     KCVT01007078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18293:15103"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84603.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          119 c          108 g           92 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtttgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007079             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20330:20231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007079
VERSION     KCVT01007079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20330:20231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84604.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          116 c          110 g           89 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagtc
      181 agggtattaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaaactcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcggt ggaagtggat
      301 ctgggacaga tttcactctc accatcagta gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007080             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13555:14879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007080
VERSION     KCVT01007080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13555:14879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..286
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <264..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84605.1"
                     /translation="CQQSYDTPYTF"
     J_segment       288..324
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>327
                     /gene="IGKC"
BASE COUNT           86 a           89 c           77 g           75 t
ORIGIN      
        1 acatgggcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
       61 ccatcacttg cagggcaagt ccgaacgtta acaactattt acattggtat cagcagaaac
      121 cagggaaagc ccctgagctc ctgatctatg ctgcatccac tttgcaaagt ggggtcccat
      181 caaggttcag cggcagtgga tctggggcag atttcactct caccatcagc agcctgcagc
      241 ctgaagatgt tgcaacttat ttctgtcagc aaagttatga taccccctac acttttggcc
      301 aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01007081             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9267:11933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007081
VERSION     KCVT01007081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9267:11933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84606.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           97 a          122 c          124 g          102 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatggtga ggatggaaac acctatttgg agtggcacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatcttg gggtttatta ctgcatgcaa gctctagagt ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01007082             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:16410:10206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007082
VERSION     KCVT01007082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16410:10206"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84607.1"
                     /translation="CQQHNTYPYTF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          104 a          117 c          105 g           92 t
ORIGIN      
        1 acatgggaga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacacagtc accatcactt gtcgggcaag tcagggcatt
      181 agtaatgatt tagcctggta tcagcagaaa ccagggaaag ccccgaagcc cctgatcttt
      241 tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gatttcactc tcgccatcag cagcctgcag tctgaagact ttgcaactta ttactgtcaa
      361 cagcataata cttacccgta cacttttggc caggggacca aggtggagat caaacgag
//
LOCUS       KCVT01007083             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17734:16197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007083
VERSION     KCVT01007083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17734:16197"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84608.1"
                     /translation="CHQYNNLPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          113 c          102 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatgcaaat cgtttggaaa ctggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca acccgaagat tttgcaactt attactgtca
      361 ccagtataat aatttaccac tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007084             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16034:9616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007084
VERSION     KCVT01007084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16034:9616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84609.1"
                     /translation="CQHSYDTPYTF"
     J_segment       386..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          116 c          106 g           97 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca gggcaagtgc
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagccc ctgagctcct
      241 gatttatgtt acatccactt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agttatgata ccccctacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007085             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:24587:10656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007085
VERSION     KCVT01007085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24587:10656"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84610.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           99 a          122 c          118 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcctg gatagtgagg atggaaacac ctatttgcac tggtacctga agaagccagg
      241 ccagtctcca cagctcttaa tttatgaagt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007086             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:24647:3081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007086
VERSION     KCVT01007086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24647:3081"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84611.1"
                     /translation="CQQYHSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          111 c          107 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ccccctgtct gcatctatag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaattggt atcagcggaa accggggaaa gcccctaaac tcctgatcaa
      241 ttatacaaac cgtttggaga atggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcatt ctcaccatca gcagcctgca acctgaggat tttgcaactt atttctgtca
      361 gcagtatcat agtttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007087             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14652:3115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007087
VERSION     KCVT01007087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14652:3115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84612.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          119 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcgagtcagg
      181 acattcgcag ttatttagcg tggtatcagc agagaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007088             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18948:10606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007088
VERSION     KCVT01007088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18948:10606"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84613.1"
                     /translation="CQQYDSDPFTF"
     J_segment       376..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT          102 a          112 c          108 g           92 t
ORIGIN      
        1 acatggggga gtcaggacac agcatggaca tgagggtccc cgctcagctc ctaggactcc
       61 tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct ccatcctccc
      121 tgtctacatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag ggcattcgca
      181 gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg
      241 cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat
      301 tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt
      361 atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa cgag
//
LOCUS       KCVT01007089             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18799:8289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007089
VERSION     KCVT01007089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18799:8289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84614.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          126 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcgggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacgga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007090             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11634:12782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007090
VERSION     KCVT01007090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11634:12782"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84615.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc cgctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007091             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:5986:11694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007091
VERSION     KCVT01007091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5986:11694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84616.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          122 c          117 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attctgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaagatg gaaacaccta tttgcactgg tacctgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007092             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11149:18681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007092
VERSION     KCVT01007092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11149:18681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84617.1"
                     /translation="CQHSYTTPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          117 c          106 g          100 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggctagttat
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc taacctcctg
      241 atctatgctg catccacttt gcaaagtggg gtcccatcta ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc gacttattac
      361 tgtcagcata gttatactac cccgttcact ttcggtgggg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007093             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24535:20231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007093
VERSION     KCVT01007093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24535:20231"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84618.1"
                     /translation="CQQDYSYPWTF"
     J_segment       385..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          115 g           91 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agtatggaca tgagggtccc cgtgcagctc
       61 ctggggctcc tgttgctctg gctccaaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgcaggagac agagtcaccg tcacttgccg ggcgagtcaa
      181 ggcattaaca aggagttaag ctggtatcag cagaaaccag ggaaagcccc tacactcctc
      241 atctatgctg cctccagttt gcagacgggg gtctcatctc ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcaacagg attatagtta cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007094             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:12719:16789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007094
VERSION     KCVT01007094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12719:16789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84619.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcattg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007095             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:9443:18851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007095
VERSION     KCVT01007095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9443:18851"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..399
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84620.1"
                     /translation="CMQNTEDPTF"
     J_segment       400..430
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>436
                     /gene="IGKC"
BASE COUNT          100 a          119 c          111 g          106 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcat cttctcacga tgagactccc tgctcagctc
       61 ctcgggctgt tgatgctctg ggtccctggg tccagtgggg atattgtgat gacccagact
      121 ccactctcgc tgcccgtcac ccctggagag ccggcctcca tctcctgcag gtctagtcaa
      181 agccttctgc atagtaatgg aaacacctat ttgcattggt acctgcagaa gccaggccag
      241 tctccacgtc tcctgatcta taaagttacc aatcgggaat ctggggtccc agacaggttc
      301 agtggcagtg ggtcaggcac agatttcaca ctgaaaatca gcagggtgga gcctgaagat
      361 gttggtgttt attattgcat gcaaaataca gaagatccca ctttcggccc cgggaccaaa
      421 ctggatatca tacgag
//
LOCUS       KCVT01007096             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14473:10335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007096
VERSION     KCVT01007096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14473:10335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84621.1"
                     /translation="CMQNTEDPTF"
     J_segment       399..429
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>435
                     /gene="IGKC"
BASE COUNT          100 a          119 c          111 g          105 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctgggt ccagtgggga tattgtgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca tagtaatgga aacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacgtct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gatttcacac tgaaaatcag cagggtggag cctgaagatg
      361 ttggtgttta ttattgcatg caaaatacag aagatcccac tttcggcccc gggaccaaac
      421 tggatatcat acgag
//
LOCUS       KCVT01007097             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11634:5657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007097
VERSION     KCVT01007097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11634:5657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84622.1"
                     /translation="CQQGNSNPVTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          112 c          112 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 ccattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tatattatgc aagtagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agactttgca acttattact
      361 gtcagcaggg caatagtaat cctgtcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007098             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21570:19401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007098
VERSION     KCVT01007098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21570:19401"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84623.1"
                     /translation="CQQYNNDPPTF"
     J_segment       390..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          107 a          123 c          106 g           91 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctaggac tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg tcgggcgagt
      181 cagggcattg gcagtcattt agcgtggtat cagcagaaac cagggaaagc cccgaagccc
      241 ttgatctatt acgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag acttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcaac agtataacaa tgaccctccc actttcggcc ccgggaccaa actggatatc
      421 aaacgag
//
LOCUS       KCVT01007099             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12776:19474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007099
VERSION     KCVT01007099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12776:19474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84624.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gctcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007100             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17151:14618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007100
VERSION     KCVT01007100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17151:14618"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84625.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007101             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:10789:3868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007101
VERSION     KCVT01007101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10789:3868"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84626.1"
                     /translation="CQQHNSYPLTF"
     J_segment       384..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          106 a          121 c          106 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taatagttac ccactcactt tcggcggagg gaccaaggtg gagatcagac
      421 gag
//
LOCUS       KCVT01007102             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17171:7115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007102
VERSION     KCVT01007102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17171:7115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..426
                     /note="immunoglobulin light chain variable region"
     V_region        87..426
     V_segment       87..388
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84627.1"
                     /translation="CMQALEFPFTF"
     J_segment       390..426
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           94 a          123 c          110 g          102 t
ORIGIN      
        1 acatggggtc aggtcacctt ctcacaatga ggctccctgc tcagctcctg ggactgctaa
       61 tgctctggct ccctggatcc actggggaca ttgtgatgac ccagactcca ctctccctgc
      121 ccgtcaccct tggaggaccg gcctccatct cctgcaggtc aagtcagagc ctcttggata
      181 gtgaggatga aaacacctat ttggaatggt acatgcagaa gccaggccag tctccacagc
      241 tcttgattta tgaggtttcc atccgggcct ctggagtccc agacaggttc agtggcagtg
      301 ggtcagacac tgatttcaca ctgaacatca gcagagtgga gcctgaggat cttggggttt
      361 actactgcat gcaagctcta gagtttccct tcactttcgg ccccgggacc aaactggata
      421 tcaaacgag
//
LOCUS       KCVT01007103             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25177:17594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007103
VERSION     KCVT01007103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25177:17594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-82"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84628.1"
                     /translation="CMQGTHLPWTF"
     J_segment       398..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           94 a          125 c          118 g          101 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgtt agtgctctgg ctccctgggt ccactggcga cactgtgatg acacagaccc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcctaca tagaaatgga tacacctatt tgtactggta cctgcagagg ccgggccagt
      241 ctccacagct cctgatgtat tttgtttcaa accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tacgaatcag cagggtggag gctgaggata
      361 ttgggattta ttattgcatg caaggtacac accttccgtg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01007104             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:10513:4555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007104
VERSION     KCVT01007104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10513:4555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84629.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatttctg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007105             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15355:19200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007105
VERSION     KCVT01007105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15355:19200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84630.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          111 c          113 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc ggcaggagac agagtcatta tcacttgtcg ggcgagtcag
      181 gacattagaa gttatttagc gtggtatcgg cagaagccag ggaaagcccc ggagcccttg
      241 atctattacg catccgtttt ggaaaatggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgg aacttattac
      361 tgtcaacagt atgacagtga ctcactcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007106             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:17230:1974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007106
VERSION     KCVT01007106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17230:1974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84631.1"
                     /translation="CQQYYSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          114 c          113 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatcg gcaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattagcag ttatttagcg tggtatcggc agaagccagg gaaagccccg gagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgga actttttact
      361 gtcaacagta ttacagtgac tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007107             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14770:13082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007107
VERSION     KCVT01007107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14770:13082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84632.1"
                     /translation="CQQYNSDPYNF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          112 a          113 c          106 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcag cagaaaccag gaaaagcccc gaaggccttg
      241 atctattacg catccatttt agaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg acgattttgc aacttattac
      361 tgtcaacagt ataacagtga cccatacaat tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007108             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5917:17242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007108
VERSION     KCVT01007108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5917:17242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84633.1"
                     /translation="CLQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc ctgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007109             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16792:5485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007109
VERSION     KCVT01007109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16792:5485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84634.1"
                     /translation="CLQYKSFPNTF"
     J_segment       389..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          118 c           99 g           96 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag catggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg tgggagacac tgtcaccatc acttgccgga caagtcaagg
      181 tattaccaat tatttacatt ggtttcagca gaaaccaggg agagccccta agctcctgat
      241 ctatgaaaca tccagtttga caagtggggt cccatcaagg ttcagcggca gtgcatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttactactg
      361 tctacagtat aaaagtttcc cgaacacctt tggccagggg accaaactgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007110             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:21441:14170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007110
VERSION     KCVT01007110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21441:14170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84635.1"
                     /translation="CQQHDNSPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          117 c          104 g           93 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccacatg acccagtctc
      121 cttcctccct gtctgcatct ataggcgaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattaacga ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag attcagtgga agtggatctg
      301 gaacagattt cactctcacc atcagcagcc tgcaggctga agatttcgca acatatttct
      361 gtcaacaaca tgataattcc cctcccactt tcggtggagg gactaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007111             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19305:8029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007111
VERSION     KCVT01007111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19305:8029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84636.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct actcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007112             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7545:20789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007112
VERSION     KCVT01007112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7545:20789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84637.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcttgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007113             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:8449:6260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007113
VERSION     KCVT01007113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8449:6260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84638.1"
                     /translation="CIQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          117 g          109 t
ORIGIN      
        1 acctggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctcctt ctcctgtagg tctagtcaca
      181 gcctcttgga tagtgaggat ggaaatatcc atttggattg gtatctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ttagtggcag tgggtcagac actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttactactgc atacaatctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007114             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12368:8572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007114
VERSION     KCVT01007114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12368:8572"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84639.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007115             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22520:19635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007115
VERSION     KCVT01007115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22520:19635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84640.1"
                     /translation="CMQALEFPFTF"
     J_segment       403..440
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          124 c          117 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgata atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt ccattcacct tcggccccgg
      421 gaccaaactg gatatcaaac gag
//
LOCUS       KCVT01007116             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24098:15809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007116
VERSION     KCVT01007116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24098:15809"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84641.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattaccaa tgatttagcc tggtatcaac agagaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagtc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007117             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11076:18658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007117
VERSION     KCVT01007117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11076:18658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84642.1"
                     /translation="CQQNSNWPLTF"
     J_segment       379..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          100 a          122 c          112 g           84 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ccccagcaca gcttctcttc
       61 ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca gtctccagcc
      121 accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag tcagagtgtc
      181 agcagcagcg tagcctggta ccagcaaaaa cctgggcagg ctcccagact cctcatctat
      241 ggtgcatcca acagggccac tggcatccca gacaggttca gtggcagtgg gtctgggaca
      301 gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta ttattgtcag
      361 cagaatagta actggcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01007118             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15230:14944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007118
VERSION     KCVT01007118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15230:14944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84643.1"
                     /translation="CQQHNNYSPTF"
     J_segment       393..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          108 a          120 c          109 g           93 t
ORIGIN      
        1 acatggggat gtaggagtca gaaccactca ggacacagca tggacatgag ggtccccgct
       61 cagctcctgg ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc
      121 cagtctccac cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca
      181 agtcagggca ttagcaatga tttagcctgg tatcagctga aaccagggaa agccccgaag
      241 cccctgatct attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt
      301 ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact
      361 tattactgtc aacagcataa taattactct cccactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01007119             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:22627:13611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007119
VERSION     KCVT01007119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22627:13611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84644.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          125 c          113 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01007120             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:5228:9952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007120
VERSION     KCVT01007120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5228:9952"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84645.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          122 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007121             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14912:17360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007121
VERSION     KCVT01007121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14912:17360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84646.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          123 c          123 g           98 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggactg gtacctgcag aggccaggcc
      241 agactcccca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggg
      301 tcagaggcag tgggtcagac actgagttca cactgaaaat cagcagagtg gaggctgagg
      361 atcttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007122             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16275:14925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007122
VERSION     KCVT01007122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16275:14925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84647.1"
                     /translation="CQQGHSYPWTF"
     J_segment       384..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>424
                     /gene="IGKC"
BASE COUNT          100 a          117 c          111 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca gtcgagtcta
      181 ggcattggca aatttttaaa ttggtatcag cagaaaccag ggaaagcccc caaactcctg
      241 atctataggg catccagttt gcaaactggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cgcttattac
      361 tgtcaacagg gtcatagtta cccgtggacg ttcagccaag ggaccaaggt ggagatgaaa
      421 cgag
//
LOCUS       KCVT01007123             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23628:3828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007123
VERSION     KCVT01007123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23628:3828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84648.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          124 c          114 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tacaaccgga caaatagtgc tgacgcagtc
      121 tccagacacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007124             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18854:17374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007124
VERSION     KCVT01007124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18854:17374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84649.1"
                     /translation="CQQHNTYPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          118 c          106 g           93 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 aggacattag taatgattta gcctggtatc aacagaaacc agggaaagcc ccgaagcccc
      241 tgatctttta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataatact tacccgtaca cttttggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007125             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:15973:15000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007125
VERSION     KCVT01007125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15973:15000"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84650.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtggttcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg tatgcaagct ctagagtttc cattcacctt cggccccggg
      421 accaaagtgg atatcaaacg ag
//
LOCUS       KCVT01007126             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7262:6098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007126
VERSION     KCVT01007126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7262:6098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84651.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          125 c          110 g           85 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca acagcttagc ctggtaccaa caaaaacctg agcagcctcc caggctcctc
      241 atctatggtg catccagcag ggccactggc atcccagaca ggttcagagg cagtgggtct
      301 gggacagact tcactctcac catcaccagc ctggagcctg aagatgttgc agtttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007127             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22670:19314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007127
VERSION     KCVT01007127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22670:19314"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84652.1"
                     /translation="CMQALDFPWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          103 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgctgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccattttc tgtaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttgatttatg aggtttccga ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacacag atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tgggatttat tactgcatgc aagctctaga ctttccgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01007128             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25409:10112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007128
VERSION     KCVT01007128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25409:10112"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..394
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84653.1"
                     /translation="CMQSTKDPLTF"
     J_segment       396..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           96 a          123 c          111 g          104 t
ORIGIN      
        1 acatggggag gactcctcag ttcatcttct cacgatgaga ctccctgctc agctcctcgg
       61 gctgttgatg ctctgggtcc ctgggtccag tggcgatatt ttgctgaccc agactccact
      121 ctcgctgccc gtcacccctg gagagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tctgcatagt aatggataca cctatttgca ttggtacctg cagaagccag gccagtctcc
      241 acggctcctg atctataaag ttaccaatcg ggaatctggg gtcccagaca ggttcagcgg
      301 cagtgggtca ggcatagatt tcacactgga aatcagcagg gtggagcctg aggatgttgg
      361 tgtttattac tgcatgcaaa gtacaaaaga tcccctcact ttcggccccg ggaccaaact
      421 ggatatcaaa cgag
//
LOCUS       KCVT01007129             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:10930:3925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007129
VERSION     KCVT01007129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10930:3925"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..286
                     /note="immunoglobulin light chain variable region"
     V_region        2..286
     V_segment       2..234
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <226..>258
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84654.1"
                     /translation="CLQGDTAPFTF"
     J_segment       251..286
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        287..>289
                     /gene="IGKC"
BASE COUNT           77 a           69 c           78 g           65 t
ORIGIN      
        1 acatgggcag gagacagagt caccatcact tgccgggcaa gtcagggcat taacgattat
       61 ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta tgctgcatcc
      121 agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac agaattcact
      181 ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct acagggtgat
      241 actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007130             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:7440:9788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007130
VERSION     KCVT01007130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7440:9788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84655.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          116 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggatcacga ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007131             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12881:5478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007131
VERSION     KCVT01007131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12881:5478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84656.1"
                     /translation="CLQESNWSYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat agtaccggag aaatagtggt gacacagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcaaaa gcaggttagc ctggtaccag cagaaacctg ggcaagctcc caggctcctc
      241 atgtatgatg cgtccagcag ggccactggc atcccagaca ggttcactgg cagcgggtct
      301 gggccagagt tcactctcac catcagcagc ctggagcctg aagatgttgc ggtttatttc
      361 tgtcttcagg agagtaactg gtcgtacagc tttgcccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007132             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20864:10611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007132
VERSION     KCVT01007132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20864:10611"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84657.1"
                     /translation="CQQHDNSPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          116 c          113 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 agagtattaa cgactggttg gcctggtatc aacagagacc agggaaggcc cctaagctcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgataat tccccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007133             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9593:11910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007133
VERSION     KCVT01007133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9593:11910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84658.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          118 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007134             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21323:10506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007134
VERSION     KCVT01007134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21323:10506"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84659.1"
                     /translation="CMQALEFPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga catagtgatg acccagactc
      121 cactctccct gcccgtcccc cttggagagc cggcctccat ctcctgtagg tctggtcaga
      181 gcctcttgga cagtgaggaa ggaaaaacct ttttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcctgatt tatgacgttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaggctc tggagtttcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007135             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16947:8917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007135
VERSION     KCVT01007135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16947:8917"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..377
                     /note="immunoglobulin light chain variable region"
     V_region        64..377
     V_segment       64..347
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84660.1"
                     /translation="CLQGDSTPFTF"
     J_segment       354..377
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>388
                     /gene="IGKC"
BASE COUNT           89 a          106 c          102 g           91 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctgggg ctccttctgc tctggctccc aggtgccaga
       61 tgtgacatcc agatgaccca gtctccatct tccctgtctg catcggtagg agacagagtc
      121 accatcactt gccgggcaag tcaggacatt agcgattatt taagttggta tcagcagaaa
      181 ccgggaaaag ctcctaagcg cctaatctat gctgcatcca ctttggaaag tggggtccca
      241 tcaaggttca gcggcagtgg atctgggaca gagttcactc tcaccatcag cagcctgcag
      301 cctgaagatt ttgcgactta ttactgtcta cagggtgata gtaccccgtt cacttttggc
      361 caggggacca aagtggacgt caaacgag
//
LOCUS       KCVT01007136             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:7865:10269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007136
VERSION     KCVT01007136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7865:10269"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84661.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga a
//
LOCUS       KCVT01007137             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20736:18637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007137
VERSION     KCVT01007137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20736:18637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84662.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          118 c          104 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01007138             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9714:14173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007138
VERSION     KCVT01007138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9714:14173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84663.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          126 c          112 g          106 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcttggat agtgaggatg aaaacaccta tttggaatgg tacgtgcaga agccaggcca
      241 gtctccacag ctgttgattt atgaggtttc cacccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaacatc agcagagtgg aggctgagga
      361 tcttggggtt tattactgca tgcaagctct agagtttcca ttcactttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01007139             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:24859:14156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007139
VERSION     KCVT01007139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24859:14156"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84664.1"
                     /translation="CMQPLEFPWTF"
     J_segment       406..443
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           98 a          122 c          121 g          105 t
ORIGIN      
        1 acatggggga tctgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccagt ggggacattg tgatgaccca
      121 gactccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagaccctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      241 aggccagtct cctcaactct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca acctctagag tttccgtgga cgttcggcca
      421 ggggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01007140             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8651:10772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007140
VERSION     KCVT01007140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8651:10772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84665.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          116 c          102 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01007141             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:10540:13456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007141
VERSION     KCVT01007141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10540:13456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..411
                     /note="immunoglobulin light chain variable region"
     V_region        90..411
     V_segment       90..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84666.1"
                     /translation="CQQYDSDSLTF"
     J_segment       378..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           98 a          111 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcaggacac agcatggaca tgagggtccc cgctcagctc ctaggactcc
       61 tgctgctctg tctcccaggt gccaattgtg acatccagat gacccagtct ccatcctccc
      121 tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag gacattcgca
      181 gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg
      241 cgtccacttt ggagagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagagt
      301 tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt
      361 atgacagtga ttcgctgact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007142             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:12181:17804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007142
VERSION     KCVT01007142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12181:17804"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84667.1"
                     /translation="CQQGHSYPWTF"
     J_segment       384..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>424
                     /gene="IGKC"
BASE COUNT           99 a          117 c          113 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtccgcatc tgtaggagac acagtcacga tcacttgcca gtcgagtcta
      181 ggcattggca aatttttaaa ttggtatcag cagaaaccag ggaaagcccc caaactcctg
      241 atctataggg catccagttt gcaaactggg attccctctc ggtgcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cgcttattac
      361 tgtcaacagg gtcatagtta cccgtggacg ttcggccaag ggaccaaggt ggagatgaaa
      421 cgag
//
LOCUS       KCVT01007143             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:19299:19944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007143
VERSION     KCVT01007143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19299:19944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84668.1"
                     /translation="CMQALEFPFTF"
     J_segment       400..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          124 c          115 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 gctctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgataatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcca ttcaccttcg gccccgggac
      421 caaactggat atcaaacgag
//
LOCUS       KCVT01007144             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10068:16116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007144
VERSION     KCVT01007144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10068:16116"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84669.1"
                     /translation="CIQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          121 c          115 g          110 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc caccggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccttc tcctgtaggt ctagtcacag
      181 cctcttggat agtgaggatg gaaatatcca tttggattgg tatctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 tagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagggtgg aggctgagga
      361 tgttggggtt tactactgca tacaatctct agagtttcct tggacgttcg gccaggggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007145             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19995:14701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007145
VERSION     KCVT01007145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19995:14701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84670.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          115 c          111 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc cgtcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacccg ttcactttcg gtggagggac caaggtagag atcaaacgag
//
LOCUS       KCVT01007146             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20908:15715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007146
VERSION     KCVT01007146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20908:15715"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84671.1"
                     /translation="CQQDFDWPPPF"
     J_segment       391..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          126 c          110 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaaactcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcaat gccagtgggt
      301 ctggaacaga gttttctctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 attgtcagca ggattttgac tggcctccgc cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007147             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11351:6082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007147
VERSION     KCVT01007147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11351:6082"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84672.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactact aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccagggtgga aatcaaacga g
//
LOCUS       KCVT01007148             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13960:4281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007148
VERSION     KCVT01007148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13960:4281"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..264
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <242..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84673.1"
                     /translation="CMQSLEFPLTF"
     J_segment       265..302
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>305
                     /gene="IGKC"
BASE COUNT           73 a           69 c           91 g           72 t
ORIGIN      
        1 acatggggga gagccggcct ccatctcctg caggtctagt cagagcctct tggatagtga
       61 ggatggaaac acctatttgg aatggtacct gcagaagcca ggccagtctc cacagctctt
      121 gatttatgag gtctccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      181 agacactaat ttcacactga gaatcagtag agtggaggct gaggatgttg gggtttatta
      241 ctgcatgcaa tctctagagt ttccgctcac tttcggtgga gggaccaagg tggagatcaa
      301 acgag
//
LOCUS       KCVT01007149             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19465:20595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007149
VERSION     KCVT01007149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19465:20595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84674.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          117 c          103 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgagac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007150             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:13488:11758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007150
VERSION     KCVT01007150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13488:11758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84675.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat taggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01007151             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:29236:11344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007151
VERSION     KCVT01007151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:29236:11344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84676.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaagttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007152             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24205:8912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007152
VERSION     KCVT01007152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24205:8912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84677.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          118 g          107 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007153             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9189:15467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007153
VERSION     KCVT01007153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9189:15467"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84678.1"
                     /translation="CLQGDTSPFSF"
     J_segment       391..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          114 c          114 g           97 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagcca
      181 ggacattaac gattatttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatctatgct gcatccagtt tggagagtgg ggtcccatct aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagtct gaggattttg caacttatta
      361 ctgtctacag ggtgatactt ccccgtttag tttcggcgga gggacccagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007154             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:19972:4789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007154
VERSION     KCVT01007154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19972:4789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..340
                     /note="immunoglobulin light chain variable region"
     V_region        19..340
     V_segment       19..297
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>312
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84679.1"
                     /translation="CQQHDNMPLTF"
     J_segment       303..340
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        341..>343
                     /gene="IGKC"
BASE COUNT           93 a           88 c           89 g           73 t
ORIGIN      
        1 acatggggtg ccagatgtga catccagatg acccagtctc catcctccct gtctgcatct
       61 gtgggagaca gagtcaccat cacttgcaga gccagtcagg gtattagcaa ctggttggcc
      121 tggtatcaac agaaaccagg gaaagcccct aagctcctga tctatagggc atggaatctg
      181 gaaacagggg tcccatcaag gttcagtgga agtggatccg ggacagattt cactctcacc
      241 atcagcagcc tgcagcctga agatttcgca acatattact gtcaacagca tgataatatg
      301 ccgctcactt tcggtggagg gaccaaggtg gacatcaaac gag
//
LOCUS       KCVT01007155             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:24088:8012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007155
VERSION     KCVT01007155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24088:8012"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84680.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          122 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtccgcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007156             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22036:9772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007156
VERSION     KCVT01007156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22036:9772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84681.1"
                     /translation="CQQYNSEPRTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          118 c          114 g           91 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaac ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtataaca gtgagccgcg cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01007157             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7669:12481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007157
VERSION     KCVT01007157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7669:12481"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84682.1"
                     /translation="CLQGDTSPFTF"
     J_segment       389..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          114 c          112 g           98 t
ORIGIN      
        1 acaatggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaag tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaac gattatttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatctatgct gcatccagtt tggagagtgg ggtcccatcg agattcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagtct gaggattttg caacttatta
      361 ctgtctacag ggtgatactt ccccgtttac tttcggcgga gggacccagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007158             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6610:2852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007158
VERSION     KCVT01007158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6610:2852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    34..310
                     /note="immunoglobulin light chain variable region"
     V_region        34..310
     V_segment       34..272
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84683.1"
                     /translation="CLQGYNTPVTF"
     J_segment       275..310
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>313
                     /gene="IGKC"
BASE COUNT           72 a           82 c           88 g           71 t
ORIGIN      
        1 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcgt cacttgccga
       61 gccagtcagg gtattagcag ttggttagcc tggtatcagc agagaccagg gaaagcccct
      121 aaactcctga tctatagggc gtccagtttg gcaagtgggg tcccgtcaag gttcagcggc
      181 agtggatctg ggacggatta cactctcacc atcagcagcc tgcagcctga agattttgca
      241 acttattttt gtctgcaggg ttacaatacc ccggtcactt tcggcggagg gaccaaggtg
      301 gagatcaaac gag
//
LOCUS       KCVT01007159             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19623:9863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007159
VERSION     KCVT01007159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19623:9863"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84684.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacagct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat ccgcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007160             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20569:20847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007160
VERSION     KCVT01007160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20569:20847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84685.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcattggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007161             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10992:3689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007161
VERSION     KCVT01007161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10992:3689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84686.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaacctggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007162             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:26099:4344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007162
VERSION     KCVT01007162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26099:4344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..415
                     /note="immunoglobulin light chain variable region"
     V_region        97..415
     V_segment       97..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84687.1"
                     /translation="CYQYSSGYSF"
     J_segment       382..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           95 a          121 c          113 g           89 t
ORIGIN      
        1 acatgggggc tgctaggtta ggacccagaa ggaaccatgg aagccccagc tcagcttctc
       61 tgccttctgc tactctggct cccaggtacc gccggacaag ttatattgac acagtctcca
      121 gccaccctgt ctttgtctcc cggggaaaga gccactctct cctgcagggc cagtcagagt
      181 gttagcagct atttagcctg gtaccagcaa aaacctgggc aggctcccag gctcctcatc
      241 catagtgcgt ccagcagggc cactgccatc cctgacaggt tcagtggcag tgggtctggg
      301 acagagttca ccctcaccat cagcagcctg gagcctgaag atgttggaat ttatcactgc
      361 tatcagtata gcagcgggta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007163             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5689:15378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007163
VERSION     KCVT01007163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5689:15378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..411
                     /note="immunoglobulin light chain variable region"
     V_region        126..411
     V_segment       126..373
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84688.1"
                     /translation="CLQDIQFPLTF"
     J_segment       374..411
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>414
                     /gene="IGKC"
BASE COUNT           88 a          110 c          113 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgttg atcagactcc
      121 agtctccagt ctccatctcc tgcaggtcta gtcagagcct ccttcaaact aatggaaaca
      181 cctatttgtt ttggtacctg cagaagccag gccagtctcc acaactcctg atctacttgg
      241 gttccaaccg ggcctctgga gtcccagaca ggttcagtgg cagtgggtca ggcactgatt
      301 tcacactgaa aatcagccgg gtggaggctg aagatgttgg ggtttattac tgcttgcaag
      361 atatacagtt tccgctcact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007164             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14879:2322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007164
VERSION     KCVT01007164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14879:2322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..412
                     /note="immunoglobulin light chain variable region"
     V_region        73..412
     V_segment       73..375
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <352..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84689.1"
                     /translation="CMQALEFPLTF"
     J_segment       378..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>415
                     /gene="IGKC"
BASE COUNT           92 a          109 c          115 g           99 t
ORIGIN      
        1 acatgggtca caatgaggct ccctgctcag ctcctgggac tgctaatgct ctggctccct
       61 ggatccagtg gggacattgt gatgacccag actccactct ccctgcccgt cacccttgga
      121 gagccggcct ccatctcctg taggtctagt cagagcctct tggatagtga agatggaaat
      181 acctatttgg aatggcaccg gcagatgcca ggccagtctc cacagctctt gatttatgag
      241 gtttccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc agacactgat
      301 ttcactctga aaatcagcag agtggaggct gaggatgttg gggtttatta ctgcatgcaa
      361 gctctagagt ttcctctgac gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01007165             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10614:18301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007165
VERSION     KCVT01007165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10614:18301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84690.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagtgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007166             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21480:14057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007166
VERSION     KCVT01007166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21480:14057"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84691.1"
                     /translation="CQQNSNWPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          124 c          110 g           84 t
ORIGIN      
        1 acatgggggg ctcagttagg acccagaggg aaccatggaa gccccagcac agcttctctt
       61 cctcctgctg ctctggctcc cagataccac cggagaaata gtgatgacgc agtctccagc
      121 caccctgtct ttgtctccag gagaaagagc caccctctcc tgcagggcca gtcagagtgt
      181 cagcaacagc ttagcctggt accaacaaaa acctgggcag cctcccaggc tcctcatcta
      241 tggtgcatcc agcagggcca ctggcatccc agacaggttc agaggcagtg ggtctgggac
      301 agacttcact ctcaccatca ccagcctgga gcctgaagat gttgcagttt attattgtca
      361 gcagaatagt aactggcctc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007167             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:24562:14522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007167
VERSION     KCVT01007167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24562:14522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..437
                     /note="immunoglobulin light chain variable region"
     V_region        100..437
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84692.1"
                     /translation="CMQSLDFPLTF"
     J_segment       402..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgttat gacccagact
      121 ccattctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcctgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccaggcagg
      301 ttcagtggca gtgggtcaga cacagatttc acactgaaaa tcagcagagt ggagactgag
      361 gatgttgggg tttattactg catgcagtct ctagattttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaatcg ag
//
LOCUS       KCVT01007168             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:27235:6381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007168
VERSION     KCVT01007168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:27235:6381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84693.1"
                     /translation="CLQYKSYPFTF"
     J_segment       364..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          101 a          109 c           93 g          101 t
ORIGIN      
        1 acatggggac agcatggaca tgagggcccc cgctcatctc ctagggctct tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gactcagtct ccatcttccc tgtctgcatc
      121 tgtaggagac actgtcacca tcacttgccg ggcaagtcag gttattatca attatttaaa
      181 ttggtttcag cagaaaccag ggaaagcccc taagctcctg atttatgctg catccagatt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtctacagt ataaaagtta
      361 cccattcact ttcggccccg ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01007169             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:20013:3194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007169
VERSION     KCVT01007169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20013:3194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84694.1"
                     /translation="CHQYNNLPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          114 c          104 g           97 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaaca tttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattatg caaatcgttt ggaaactggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcaacagc ctgcaacccg aagattttgc aacttattac
      361 tgtcaccagt ataataattt accactcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007170             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:2431:11254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007170
VERSION     KCVT01007170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:2431:11254"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84695.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg tcccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007171             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9947:7526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007171
VERSION     KCVT01007171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9947:7526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84696.1"
                     /translation="CQHGYGIQLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          116 c          112 g           97 t
ORIGIN      
        1 acatggggga gtcagtccca gtcaggactc agcatggaca tgagggcccc cactcagctc
       61 ctggggttcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac agagtcacca tctcttgcca ggcgagtcag
      181 gacattagca atgatttagc ctggtatcag cagaaaccgg gaaaagcccc taggctcctg
      241 atgtataagg catccgcttt gcagattggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcaacagc ctgcagcctg aagattttgc aacttactac
      361 tgtcaacatg gttatggtat ccagctcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01007172             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14852:13836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007172
VERSION     KCVT01007172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14852:13836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84697.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          117 c          123 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacttgca gaaggcaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagc cactgatttc aaactgaaca tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007173             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23443:12723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007173
VERSION     KCVT01007173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23443:12723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84698.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa taagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007174             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:20168:21163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007174
VERSION     KCVT01007174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20168:21163"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84699.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggccacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007175             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14870:5036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007175
VERSION     KCVT01007175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14870:5036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84700.1"
                     /translation="CQQDYHWPPTF"
     J_segment       393..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agacatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagcc
      181 agagtgttgg cagcacctta acctggtacc accagaagcc tgggcaggct cccaagctcc
      241 tcatctatgg tccttccatc cgggccagcg gcatcccaga caggtttagt ggcagtgggt
      301 ctggaacaga atttactctc accatcagca gcctggagac tgaagatgtt ggagtttatt
      361 actgtcagca ggattatcac tggcctccga cattcggcca agggaccaag gtggaattca
      421 aacgag
//
LOCUS       KCVT01007176             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5393:7426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007176
VERSION     KCVT01007176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5393:7426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84701.1"
                     /translation="CQQYDRFPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          117 c          100 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg gacaagtcaa
      181 gacattacca gttatttaaa ctggtatcag cagaaaccgg ggaaagcccc taaactcctg
      241 atctattata caaatcgttt ggaaactggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt atgataggtt tccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01007177             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21638:18736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007177
VERSION     KCVT01007177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21638:18736"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84702.1"
                     /translation="CQQYNSLPLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          107 c          108 g           98 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgtt ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagcagata tttaaattgg tatcagcaga aaccggggaa agcccctaag ttcctgatct
      241 attatgtaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgaaga ttttgcaact tattattgtc
      361 aacagtataa tagtttaccg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007178             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11494:8220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007178
VERSION     KCVT01007178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11494:8220"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..331
                     /note="immunoglobulin light chain variable region"
     V_region        10..331
     V_segment       10..293
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84703.1"
                     /translation="CQHSFRTPYSF"
     J_segment       294..331
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           85 a           87 c           83 g           79 t
ORIGIN      
        1 acatggggtg acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac
       61 agagtcaatg tcacttgcag ggctagtgag agcgttagca ccaaattaca ttggtatcag
      121 cagaaaccag ggaaagcccc taagctcctg atctttgctg cgtccacttt gcaaagtggg
      181 gtcccatcaa ggttcagcgg cagtggatct ggaacagatt tcactctcac catcagcagc
      241 ctgcagcctg aagatgtcgc aactttttac tgtcagcata gttttcgtac cccgtacagt
      301 tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01007179             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13167:5700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007179
VERSION     KCVT01007179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13167:5700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84704.1"
                     /translation="CQQGYTYLYSF"
     J_segment       382..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 cctcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctga
      241 tctatagggc atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ctgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007180             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:21107:14185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007180
VERSION     KCVT01007180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21107:14185"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84705.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggcaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007181             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14639:16852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007181
VERSION     KCVT01007181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14639:16852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..384
                     /note="immunoglobulin light chain variable region"
     V_region        63..384
     V_segment       63..346
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84706.1"
                     /translation="CQHSFRTPYSF"
     J_segment       347..384
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           90 a          109 c           97 g           91 t
ORIGIN      
        1 acatgggggc ctctgctcag ctcctagggc tcctgctgct ctggctccca ggcgccagat
       61 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      121 ccgtcacttg cagggctagt gagagcgtta gcaccaaatt acattggtat caacagaaac
      181 cagggaaagc ccctaagctc ctgatctttg ctgcgtccac tttgcaaagt ggggtcccat
      241 caaggttcag cggcagtgga tctggaacag atttcactct caccatcagc agcctgcagc
      301 ctgaagatgt tgcaactttt tactgtcagc atagttttcg taccccgtac agttttggcc
      361 aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01007182             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14525:15704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007182
VERSION     KCVT01007182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14525:15704"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..311
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84707.1"
                     /translation="CMQALEFPWTF"
     J_segment       312..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           82 a           86 c          102 g           82 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
       61 ccggcctcca tgtcctgcag gtctagtcag agtctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt
      181 tccaaccggg cctctggagt cccagacagg ttcagtggcg gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgat gatgttgggg tttattactg catgcaagct
      301 ctagagtttc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007183             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15610:11837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007183
VERSION     KCVT01007183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15610:11837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84708.1"
                     /translation="CQHYISSPFTF"
     J_segment       383..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT           94 a          127 c          110 g           92 t
ORIGIN      
        1 acatggggga gctgctcagt taggacccag agagaaccat ggaaatccca gctcagcttc
       61 tcttcctcct gctactgtgg ctcccaggta ccaccggaca agttatattg actcagtctc
      121 caggcaccct gtctttgtct ccaggggaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgttggcag cagcttagcc tggtaccagc agaaacctgg gcaggccccc aggctcctca
      241 tctatggtgc atccagcagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agattttgca gtgtattact
      361 gtcagcacta tattagctcc ccattcactt tcggccccgg gaccaaactg gatatcagag
      421 gag
//
LOCUS       KCVT01007184             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:28292:8936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007184
VERSION     KCVT01007184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:28292:8936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84709.1"
                     /translation="CLQGYSPPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcatttac gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatctatgct gcatccagtt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca tcatcaacac cctgcagcct gaagattttg caacttatta
      361 ctgtctacag ggttatagtc ccccgtggac gttcggccaa gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007185             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:20104:13579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007185
VERSION     KCVT01007185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20104:13579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84710.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc attcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007186             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17993:11205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007186
VERSION     KCVT01007186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17993:11205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..388
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84711.1"
                     /translation="CQQYNSLPRTF"
     J_segment       390..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>428
                     /gene="IGKC"
BASE COUNT          109 a          112 c          112 g           95 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gccgggcaag
      181 tcagggcatt agtcaatatt taaattggta tcagcagaaa ccggggaaag cccctaaggt
      241 cctcatctat tatgtaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaggatt ttgcaactta
      361 ttactgtcaa cagtataata gtttacctcg gacgttcggc caagggacca aggtggaaat
      421 cagacgag
//
LOCUS       KCVT01007187             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12746:19693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007187
VERSION     KCVT01007187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12746:19693"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84712.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          127 c          110 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga gagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctttggt acatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tcgaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007188             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22165:14201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007188
VERSION     KCVT01007188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22165:14201"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84713.1"
                     /translation="CQQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          115 a          108 c          101 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tgggactcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaatat ttatttaaat tggtatcaac aaaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtatcacc atcaacagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacactt ttggccacgg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007189             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:22783:10436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007189
VERSION     KCVT01007189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22783:10436"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84714.1"
                     /translation="CHQYNNLPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          113 c          104 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaaca tttatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattatg caaatcgttt ggaaactggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcaacagt ctgcaacccg aagattttgc aacttattac
      361 tgtcaccagt ataataattt accactcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007190             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18704:9459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007190
VERSION     KCVT01007190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18704:9459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84715.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagac ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccaaagtgga gattaaacga g
//
LOCUS       KCVT01007191             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5306:16228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007191
VERSION     KCVT01007191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5306:16228"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84716.1"
                     /translation="CQQYNNLPLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          114 c          108 g           96 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggccattag cagttattta aattggtatc agcagaagcc ggggaaagcc cctaacctcc
      241 tgatctatta tacaaaccgt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtcaaca gtataataat ttaccgctca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007192             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:18038:10144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007192
VERSION     KCVT01007192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18038:10144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84717.1"
                     /translation="CQHSFDTPYTF"
     J_segment       383..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          118 c          107 g           96 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcaggg caagtgcgaa
      181 cgttaacaac tatttacatt ggtatcagca gaaaccaggg aaagtccctg agctcctgat
      241 ctatgctgca tcgtctttgc aaagtggggt cccatcaagg ttcagcggca gtgggtctgg
      301 gacagatttc accctcacca tcagcagcct gcagcctgaa gatgttgcaa cttattactg
      361 tcagcacagt tttgataccc cctacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007193             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21915:3310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007193
VERSION     KCVT01007193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21915:3310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..363
                     /note="immunoglobulin light chain variable region"
     V_region        86..363
     V_segment       86..325
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84718.1"
                     /translation="CQRYNSDPFTF"
     J_segment       326..363
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT           96 a           98 c           93 g           79 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggag acagagtaac catcacttgt cgggcgagtc
      121 aggacataag aagttattta gcgtggtatc agcagaaacc aggcaaagcc ccgaagccct
      181 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      241 ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt gcaacttatt
      301 actgtcaacg gtataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      361 aacgag
//
LOCUS       KCVT01007194             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13649:16911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007194
VERSION     KCVT01007194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13649:16911"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84719.1"
                     /translation="CQQYDSDPFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           93 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacctatta
      361 ctgtcaacag tatgacagtg atccgttcac tttcggtggg gggaccaagg tagacatcaa
      421 acgag
//
LOCUS       KCVT01007195             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:13243:17875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007195
VERSION     KCVT01007195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13243:17875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84720.1"
                     /translation="CQQDYHWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           95 a          125 c          114 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag gtctcaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctcctgggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cgcctcctta gcctggtacc agcagaaacc tgggcaggct ccccaactcc
      241 tcatctatgc tgcatccacc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gtttactctc actatcagca gtctggagcc tgaagatgtt ggattttatt
      361 tctgtcagca ggattatcac tggcctccga cgttcggcca aggggccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007196             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:10138:15714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007196
VERSION     KCVT01007196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10138:15714"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84721.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          125 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gcctcttgga ttgtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007197             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16898:11505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007197
VERSION     KCVT01007197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16898:11505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84722.1"
                     /translation="CQQYFSSPFTF"
     J_segment       385..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT           96 a          128 c          110 g           91 t
ORIGIN      
        1 acatggggaa gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttatat tgactcagtc
      121 tccagccacg ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagagctggt agcagcttag cctggtacca gcagaaacct gggcaggccc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcaccctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagcag tattttagct ccccattcac tttcggcccc gggaccaaac tggatatcag
      421 acgag
//
LOCUS       KCVT01007198             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17386:17158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007198
VERSION     KCVT01007198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17386:17158"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84723.1"
                     /translation="CLQYKSYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          113 c           97 g          103 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccat atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgcag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagtacctat ttaaattggt ttcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatct agtctggaaa gtggggtccc atcaaggttc agcggcagtg gatttgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtct
      361 acagtataaa agttatccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007199             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:27790:13329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007199
VERSION     KCVT01007199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:27790:13329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..411
                     /note="immunoglobulin light chain variable region"
     V_region        95..411
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84724.1"
                     /translation="CQQVYSNPAF"
     J_segment       381..411
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>415
                     /gene="IGKC"
BASE COUNT          101 a          111 c          106 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc caggtgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttataggaat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcaacctaca gcctgaagat tctgcaattt attactgtca
      361 acaggtttat agtaacccgg cgttcggcca agggaccaag gtggaaatca acgag
//
LOCUS       KCVT01007200             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10297:19665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007200
VERSION     KCVT01007200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10297:19665"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84725.1"
                     /translation="CQHSFRTPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          115 c          110 g           97 t
ORIGIN      
        1 atgggggagt cagtctcagt caggacacag catggacatg agggcctctg ctcagctcct
       61 agggctcctg ctgctctggc tcccaggcgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaatgtc acttgcaggg ctagtgagag
      181 cgttagcacc aaattacatt ggtatcagca gaaaccaggg aaagccccta agctcctgat
      241 ctttgctgcg tccactttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 aacagatttc actctcacca tcagcagcct gcagcctgaa gatgtcgcaa ctttttactg
      361 tcagcatagt tttcgtaccc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007201             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8625:6978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007201
VERSION     KCVT01007201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8625:6978"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84726.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007202             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18753:17426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007202
VERSION     KCVT01007202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18753:17426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84727.1"
                     /translation="CLQGDTAPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          110 g           93 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggcag gagacagagt caccatcact taccgggcaa gtcagggcat
      181 taacgattat ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcagctt attactgtct
      361 acagggtgat actgccccgt tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007203             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22800:10934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007203
VERSION     KCVT01007203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22800:10934"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..435
                     /note="immunoglobulin light chain variable region"
     V_region        96..435
     V_segment       96..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84728.1"
                     /translation="CMQPLEFPWTF"
     J_segment       398..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          103 t
ORIGIN      
        1 acatggggca cgactcctca ggtcaccttc tcacaatgag gctccctgct cagctcctgg
       61 gactgctaat gttctggctc cctggatcca gtggggacat tgtgatgacc cagactccac
      121 tgtccctgcc cgtcaccctt ggagagccgg cctccatctc ctgtgggtct agtcagagcc
      181 tcttggatag tgaggatgga aacacctatt tggaatggta cctgcagaag ccaggccagt
      241 ctccacagct cttgatttat gaggtttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcag cagagtggag gctgaggatg
      361 ttggggttta ttactgcatg caacctctag agtttccgtg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01007204             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15899:19568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007204
VERSION     KCVT01007204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15899:19568"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..421
                     /note="immunoglobulin light chain variable region"
     V_region        98..421
     V_segment       98..381
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84729.1"
                     /translation="CQQRNSYPYMCSF"
     J_segment       391..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>428
                     /gene="IGKC"
BASE COUNT          101 a          116 c          110 g          101 t
ORIGIN      
        1 acatgggagt tagacccagt ctggacgcag catggacatc agggtcctcg ctcagcttct
       61 cgggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagttga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg caagtcagga
      181 cattggcaat tatttagcct ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctataaggcg tccagtttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcag tttattactg
      361 tcaacagcgt aatagttacc cgtacatgtg cagttttggc ccggggacca aagtggagat
      421 ccgacgag
//
LOCUS       KCVT01007205             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11055:9517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007205
VERSION     KCVT01007205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11055:9517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..383
                     /note="immunoglobulin light chain variable region"
     V_region        44..383
     V_segment       44..345
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84730.1"
                     /translation="CMQVVEYPFTF"
     J_segment       346..383
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           88 a          101 c          106 g           91 t
ORIGIN      
        1 acatgggggg ctgctaatgc tctggctccc tggatccagt ggggatattg tcatgaccca
       61 gactccactc tccctgccag tcacccctgg agagccggcc tccatctcct gcaggtctag
      121 tcagagcctc ttggatagtg aggatggaaa cacctatttg gaatggtacc tgcagaagcc
      181 aggccagtct ccgcagccct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      241 caggttcagc ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      301 tgaggatgtt ggggtttatt actgtatgca agttgtagaa tatccattca ctttcggccc
      361 cgggaccaaa ctggatatca aacgag
//
LOCUS       KCVT01007206             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13917:6923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007206
VERSION     KCVT01007206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13917:6923"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84731.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          100 a          126 c          122 g           89 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gttgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 tggggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag gcaggttccg
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007207             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:12102:17441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007207
VERSION     KCVT01007207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12102:17441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84732.1"
                     /translation="CQQYNSDPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          111 c          110 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaattgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattagga attatttagc gtggtatcac cagaaaccag ggaaagcccc gaaggccttg
      241 atctattaca catccatttt ggaaaatggg gtcccatcaa ggttcagcgg cggtggatct
      301 gggacagaat tcagtctcac catcagcagc ctgcaggctg aggattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007208             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12981:3993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007208
VERSION     KCVT01007208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12981:3993"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..394
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84733.1"
                     /translation="CQRYSYSTWTF"
     J_segment       397..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          122 c          120 g           93 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat
      121 attgactcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt ggtttggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcagtatat tactgtcaga ggtatagtta ctccacgtgg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01007209             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12439:13167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007209
VERSION     KCVT01007209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12439:13167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..369
                     /note="immunoglobulin light chain variable region"
     V_region        185..369
     V_segment       185..332
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <309..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84734.1"
                     /translation="CMQTLEFPLTF"
     J_segment       333..369
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>372
                     /gene="IGKC"
BASE COUNT           76 a          104 c          103 g           89 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca
      241 gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg
      301 tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg accaaggtgg
      361 agatcaaacg ag
//
LOCUS       KCVT01007210             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5258:14639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007210
VERSION     KCVT01007210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5258:14639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84735.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtaat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tttcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcggtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007211             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18911:10452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007211
VERSION     KCVT01007211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18911:10452"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84736.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          122 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttagagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac agctcttaat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007212             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:2919:12051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007212
VERSION     KCVT01007212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:2919:12051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..357
                     /note="immunoglobulin light chain variable region"
     V_region        20..357
     V_segment       20..321
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84737.1"
                     /translation="CMQSLDFPLTF"
     J_segment       322..357
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>362
                     /gene="IGKC"
BASE COUNT           80 a           93 c          103 g           86 t
ORIGIN      
        1 acatggggga tccagtgcgg acattgttat gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcctgg atagtgagga
      121 tggaaacacc tatttggaat ggtacctgca gaagccaggc cagtctccac agctcttgat
      181 ttatgagctt tccagccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cacagatttc acactgagaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcagtct ctagattttc cgctcacttt cggtggaggg accaaggtgg agatcaatcg
      361 ag
//
LOCUS       KCVT01007213             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20220:22081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007213
VERSION     KCVT01007213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20220:22081"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..412
                     /note="immunoglobulin light chain variable region"
     V_region        99..412
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84738.1"
                     /translation="CQQYNNLPLTF"
     J_segment       386..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>423
                     /gene="IGKC"
BASE COUNT          107 a          112 c          106 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcaa ttatttaaat tggtatcaac agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattcct
      361 gtcaacagta taataattta ccgttgacgt tcggccaagg gaccatggtg gatttcaaac
      421 gag
//
LOCUS       KCVT01007214             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:27560:14496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007214
VERSION     KCVT01007214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27560:14496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84739.1"
                     /translation="CIQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atactgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cattcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007215             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12331:3061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007215
VERSION     KCVT01007215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12331:3061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..408
                     /note="immunoglobulin light chain variable region"
     V_region        95..408
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84740.1"
                     /translation="CLQGDSTPFTF"
     J_segment       385..408
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          109 g           94 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacataagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accgggaaaa gctcctaagc gcctaatcta
      241 tgctgcatcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt attactgtct
      361 acagggtgat agtaccccgt tcacttttgg ccaggggacc aaagtggacg tcaaacgag
//
LOCUS       KCVT01007216             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:7322:13677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007216
VERSION     KCVT01007216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7322:13677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84741.1"
                     /translation="CQQHNNYSPTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          120 c          109 g           91 t
ORIGIN      
        1 acatgggggg gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccaccctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag caatgattta gcctggtatc agctgaaacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataataat tactctccca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007217             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5604:22587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007217
VERSION     KCVT01007217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5604:22587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84742.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccaggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01007218             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:22983:13447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007218
VERSION     KCVT01007218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22983:13447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84743.1"
                     /translation="CEQYNSLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          112 c          105 g           97 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacgttaac atttatttaa attggtatca ccagaaaccg gggaaagccc ctaagctcct
      241 gatctattat acaaaccgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ctgtgaacaa tacaatagtt taccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007219             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:17005:17981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007219
VERSION     KCVT01007219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17005:17981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84744.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtccccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007220             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:13104:11981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007220
VERSION     KCVT01007220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13104:11981"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84745.1"
                     /translation="CLQENNWSYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          121 c          118 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tagtaccgga gaaatagtgg tgacacagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcaaa agcaggttag cctggtacca gcagaaacct gggcaagctc ccaggctcct
      241 catgtatgat gcctccagca gggccactgg catcccagac agattcactg gcagcgggtc
      301 tgggccagag ttcactctca ccatcagcag cctggagcct gaagatgttg cggtttattt
      361 ctgtcttcag gagaataact ggtcgtacag ctttggccag gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007221             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11294:18843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007221
VERSION     KCVT01007221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11294:18843"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84746.1"
                     /translation="CQQYSSLVAF"
     J_segment       381..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          105 a          106 c          110 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gccccaaagg tcctgatcta
      241 ttctgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatta gcaacctaca acctgaggat tttgcaactt attactgtca
      361 acagtatagt agtttagtcg ctttcggtgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01007222             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15247:22302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007222
VERSION     KCVT01007222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15247:22302"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    49..373
                     /note="immunoglobulin light chain variable region"
     V_region        49..373
     V_segment       49..336
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <313..>345
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84747.1"
                     /translation="CMQAREFPLTF"
     J_segment       337..373
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        374..>376
                     /gene="IGKC"
BASE COUNT           87 a           97 c          104 g           88 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagcagcaca gactccagtc
       61 tccctgcccg tcactcttgg agagccggcc tccatctcct gcatgtctag tcagagcctc
      121 ttggatagtg aggatggaaa cacctatgtg gaatggtacc tgcagaagcc aggccagtct
      181 ccacagctct tgatttatga ggtttcctac cgggcctctg gagtcccaga caggttcagt
      241 ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt
      301 ggggtttatt actgcatgca agctcgagag tttcctctca ctttcggtgg agggaccaag
      361 gtggagatca aacgag
//
LOCUS       KCVT01007223             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20507:24620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007223
VERSION     KCVT01007223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20507:24620"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84748.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcact cttggagagc cggcctccat ctcctgtagg tcaagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagaa actgacttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007224             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:19777:7421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007224
VERSION     KCVT01007224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19777:7421"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84749.1"
                     /translation="CLQGYITPYSF"
     J_segment       367..404
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           96 a          108 c          106 g           97 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tccttctgct
       61 ctggctccca ggtgccagat gtgacttcca gatgacccag tctccatctt ccctgtctgc
      121 atcggtagga gacagagtca ccatcacttg ccgggcaagt caggacatta gcgatttttt
      181 aagttggtat cagcagaaac caggaaaacc tcctaagcgc ctgatttatg ctgcatccag
      241 tttgcaaagt ggggtcccgt caaggttcag cgacagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcagc ctgaagattt tgcggcttat tactgtctac agggttatat
      361 taccccgtac agttttggcc aggggaccaa agtggagatc aaacgag
//
LOCUS       KCVT01007225             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:14969:19795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007225
VERSION     KCVT01007225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14969:19795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..413
                     /note="immunoglobulin light chain variable region"
     V_region        96..413
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84750.1"
                     /translation="CQQGYSYHPTF"
     J_segment       383..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>420
                     /gene="IGKC"
BASE COUNT           93 a          120 c          108 g           99 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgactt ccttatgacg cagtctcctt
      121 cctccctgtc cgcatctgta ggagacacag tcaccatcac ttgccaggcg agtcaagcca
      181 ttggcactaa tttaaattgg tatcagcaga gaccaggaaa agcccctaaa ctcctgatct
      241 atagggcttc cggtttgcag agtgggactc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcag tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttaccat cccactttcg gcggagggac caaggtggag atccaacgag
//
LOCUS       KCVT01007226             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12486:2637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007226
VERSION     KCVT01007226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12486:2637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    30..351
                     /note="immunoglobulin light chain variable region"
     V_region        30..351
     V_segment       30..314
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84751.1"
                     /translation="CQQHDDSPRTF"
     J_segment       316..351
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>354
                     /gene="IGKC"
BASE COUNT          100 a           96 c           84 g           74 t
ORIGIN      
        1 acatgggctg gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc
       61 tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagccac gatataaata
      121 actggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctg atctataggg
      181 catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct gggacagatt
      241 tcactctcag catcagcagc ctgcagcctg aagatttcgc aacatattac tgtcaacaac
      301 atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007227             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13589:18207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007227
VERSION     KCVT01007227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13589:18207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84752.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          111 a          120 c          110 g           87 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      181 ccacgatata aataactggt tggcctggta tcaacagaaa ccaggaaaag cccctaagct
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttca gtggaagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01007228             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:3921:10038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007228
VERSION     KCVT01007228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3921:10038"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..393
                     /note="immunoglobulin light chain variable region"
     V_region        72..393
     V_segment       72..346
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84753.1"
                     /translation="CQQHNNYSPTF"
     J_segment       359..393
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>396
                     /gene="IGKC"
BASE COUNT           96 a          112 c          100 g           88 t
ORIGIN      
        1 acatggggga catgagggtc cccgctcagc tcctggggct cctgctgctc tggctcccag
       61 gtgccagatg tgacatccag atgacccagt ctccaccctc cctgtctgca tctgtaggag
      121 acacagtcac catcacttgt cgggcaagtc agggcattag caatgattta gcctggtatc
      181 agctgaaacc agggaaagcc ccgaagcccc tgatctatta cgcatccaat ttggaaagtg
      241 gggtcccatc aaggttcagc ggcagtggat ctgggacaga tttcactctc accatcagca
      301 gcctgcagcc tgaagatttt gcaacttatt actgtcaaca gcataataat tactctccca
      361 ctttcggcgg agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01007229             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18802:14958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007229
VERSION     KCVT01007229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18802:14958"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84754.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           93 a          122 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgcgga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag cgggtcagac acagatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01007230             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:24578:12648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007230
VERSION     KCVT01007230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24578:12648"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84755.1"
                     /translation="CLQYKSFPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          113 c          101 g          101 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtgg catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtattaccaa ttatttacat tggtttcagc agaaaccagg gaaagcccct aagctcctga
      241 tctatgaaac atccagtttg gtaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca tcttattact
      361 gtctacagta taaaagtttc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007231             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10545:6169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007231
VERSION     KCVT01007231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10545:6169"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84756.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          120 c          107 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007232             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12677:12630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007232
VERSION     KCVT01007232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12677:12630"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84757.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga ttcagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag tcggcctccg tctcctgcag gtctagtcag
      181 agcctcttcg atagtgagga aggaaacacc tttttggagt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtg tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaagtgg aaatcaaacg ag
//
LOCUS       KCVT01007233             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16467:12833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007233
VERSION     KCVT01007233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16467:12833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84758.1"
                     /translation="CQQYNSEPRTF"
     J_segment       389..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          113 g           91 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgagtc
      181 agggcattcg cagttattta gcgtggtatc agcagaaacc agggaaaccc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtataacagt gagccgcgca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007234             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24529:9373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007234
VERSION     KCVT01007234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24529:9373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84759.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          104 a          125 c          120 g           87 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct
      241 cccagactcc tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt
      301 ggcagtgggt ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt
      361 gcactttatt attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01007235             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22709:8618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007235
VERSION     KCVT01007235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22709:8618"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84760.1"
                     /translation="CQQYDSFPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          114 c          101 g           99 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcagttat ttaaactggt atcagcagaa accggggaaa gcccctaaac tcctgattta
      241 ttatacaaat cgtttggaga ctggggtccc atcaaggttc agcggcagtg ggtctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtatgat agttttccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007236             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13953:12493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007236
VERSION     KCVT01007236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13953:12493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84761.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          107 a          119 c          107 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01007237             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:7324:14894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007237
VERSION     KCVT01007237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7324:14894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84762.1"
                     /translation="CLQSKNSPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g          100 t
ORIGIN      
        1 acatgggagc agcctctagt tcagctctca gaaatggggt cctgggctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggctgcaat ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accatcgtct gcagagccag tgagagtgtc
      181 aatgtctttg gaataaacct cattcactgg tatcagcaga aaccaggaca acctcctaaa
      241 cccctgattt accaagcatc caataaagaa actggggtcc cagccaggtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aagctgacga tgctgcagat
      361 tattactgtc tgcagagtaa gaattctccg tggacgtttg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01007238             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:14636:12448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007238
VERSION     KCVT01007238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14636:12448"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84763.1"
                     /translation="CQHSFRSPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          105 g           97 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccgtcact tgcagggcta gtgagagcgt
      181 taacaccaaa ttacattggt atcaacagaa accagggaaa gcccctaagc tcctgatctt
      241 tgctgcgtcc actttgcaaa gtggggtccc atcaaggttc agcggcaatg gatctggaac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat gttgcaactt tttactgtca
      361 gcatagtttt cgttccccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007239             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8306:19439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007239
VERSION     KCVT01007239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8306:19439"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84764.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggct ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007240             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:16691:16847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007240
VERSION     KCVT01007240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16691:16847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84765.1"
                     /translation="CQQYNSEPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           91 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgagc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007241             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:25211:16373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007241
VERSION     KCVT01007241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25211:16373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84766.1"
                     /translation="CMQSLEFPWTS"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           91 a          118 c          124 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgaagat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttggtt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttatttctgc atgcagagtc tggagtttcc ttggacgtcc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01007242             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14498:15114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007242
VERSION     KCVT01007242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14498:15114"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84767.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ccccagacac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007243             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24929:6680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007243
VERSION     KCVT01007243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24929:6680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..421
                     /note="immunoglobulin light chain variable region"
     V_region        102..421
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84768.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc atcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccagcg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 agcgag
//
LOCUS       KCVT01007244             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12362:17625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007244
VERSION     KCVT01007244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12362:17625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84769.1"
                     /translation="CMQALQFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaggccaggc
      241 cagtctccac acctcttgat ttatgagttt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc actctgaata tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctacaatttc cgtggacgtt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007245             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15396:14565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007245
VERSION     KCVT01007245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15396:14565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84770.1"
                     /translation="CMQALDFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          124 c          119 g          104 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctgc
      361 ggatgttggg gtttattact gcatgcaagc tctagacttt cccctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007246             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13239:7286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007246
VERSION     KCVT01007246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13239:7286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84771.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..418
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          103 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga cgtccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gatatcaacc
      421 gag
//
LOCUS       KCVT01007247             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8086:8412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007247
VERSION     KCVT01007247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8086:8412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84772.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgacg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007248             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10343:8404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007248
VERSION     KCVT01007248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10343:8404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84773.1"
                     /translation="YMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactac atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01007249             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22245:11905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007249
VERSION     KCVT01007249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22245:11905"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84774.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          121 c          108 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccacgg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007250             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12571:14679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007250
VERSION     KCVT01007250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12571:14679"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84775.1"
                     /translation="CLQGYITPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          110 g           99 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acttccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attttttaag ttggtatcag cagaaaccag gaaaacctcc taagcgcctg
      241 atttatgctg catccagttt gcaaagtggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc ggcttattac
      361 tgtctacagg gttatattac cccgtacagt tttagccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007251             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18024:23604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007251
VERSION     KCVT01007251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18024:23604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84776.1"
                     /translation="CLQESNWSYSF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag atagtaccgg agaaatagtg gtgacacagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcaa aagcaggtta gcctggtacc agcagaaacc tgggcaagct cccaggctcc
      241 tcatgtatga tgcgtccagc agggccactg gcatcccaga caggttcact ggcagcgggt
      301 ctgggccaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcggtttatt
      361 tctgtcttca ggagagtaac tggtcgtaca gctttggcca ggagaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01007252             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14739:11692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007252
VERSION     KCVT01007252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14739:11692"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84777.1"
                     /translation="CQQDYSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          120 c          117 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg cagcatctta gcctggtacc accagaaacc tgggcaggct cccaagtccc
      241 tcatctatgg tgcaaccagt agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggcgtttatt
      361 actgtcagca ggattatagc tggccactca ctttcggcgg agggaccaag gtggatatca
      421 aacgag
//
LOCUS       KCVT01007253             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8794:13289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007253
VERSION     KCVT01007253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8794:13289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84778.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          121 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacggctcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007254             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13817:9772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007254
VERSION     KCVT01007254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13817:9772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84779.1"
                     /translation="CMQALDFPYSF"
     J_segment       405..441
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          108 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga gtggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttttgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcagt gtggaggctg
      361 aggatgttgg ggtctattac tgcatgcaag ctctagactt tccttacagt tttggccagg
      421 ggaccaaagt ggagattaaa cgag
//
LOCUS       KCVT01007255             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:3741:8402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007255
VERSION     KCVT01007255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3741:8402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84780.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgccctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007256             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10194:12248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007256
VERSION     KCVT01007256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10194:12248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84781.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          104 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta cttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa gtcaaacgag
//
LOCUS       KCVT01007257             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:6358:10305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007257
VERSION     KCVT01007257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:6358:10305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..372
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84782.1"
                     /translation="CQQHNNYSPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          120 c          104 g           91 t
ORIGIN      
        1 acatgggagt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 accctccctg tctgcatctg taggagacac agtcaccatc acttgtcggg caagtcaggg
      181 cattagcaat gatttagcct ggtatcagct gaaaccaggg aaagccccga agcccctgat
      241 ctattacgca tccaatttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacaacat aataattact ctcccacttt cggcggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007258             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7023:9828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007258
VERSION     KCVT01007258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7023:9828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84783.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          127 c          111 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tggacaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatccccga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007259             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15326:9703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007259
VERSION     KCVT01007259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15326:9703"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84784.1"
                     /translation="CQQYSSDEFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          104 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctacatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 acattagcac tgatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc atccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttattact
      361 gtcaacagta tagcagtgat gaattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01007260             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17914:6153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007260
VERSION     KCVT01007260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17914:6153"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84785.1"
                     /translation="CQQGYSYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          112 g           95 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 cctcctccct gtccgcatct gtgggagacg cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taacttaaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataagac atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac ccgtggacgt tcggccaagg ggccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007261             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:23083:15144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007261
VERSION     KCVT01007261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23083:15144"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84786.1"
                     /translation="CVQAIAFPYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           93 a          119 c          120 g          102 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgtcc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggaaaca cctatttcca ctggtacctg cagaagccag gccagtctcc
      241 gcagctcctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcaag ctatagcgtt tccgtacagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01007262             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16258:18191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007262
VERSION     KCVT01007262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16258:18191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84787.1"
                     /translation="CQQHADSPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          120 c          106 g           88 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaca gccagccacg
      181 atataaataa ttggttggcc tggtatcaac agaaaccagg aaaagcccct aacctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcgag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatttcgca acatattact
      361 gtcaacagca tgctgattcc cctcggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007263             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:3332:11141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007263
VERSION     KCVT01007263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3332:11141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    161..331
                     /note="immunoglobulin light chain variable region"
     V_region        161..331
     V_segment       161..293
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84788.1"
                     /translation="CLQGYITPYSF"
     J_segment       295..331
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           77 a           91 c           90 g           76 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacttccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catccagttt gcaaagtggg
      181 gtcccgtcaa ggttcagcgg cagtggatct gggacagaat tcactctcac catcagcagc
      241 ctgcagcctg aagattttgc ggcttattat tgtctacagg gttatattac cccatacagt
      301 tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01007264             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12081:4634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007264
VERSION     KCVT01007264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12081:4634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84789.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007265             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11831:7382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007265
VERSION     KCVT01007265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11831:7382"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84790.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagata acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007266             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:19633:19157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007266
VERSION     KCVT01007266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19633:19157"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84791.1"
                     /translation="CQQHNGYPATF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          118 c          109 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctgcga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007267             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19712:8460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007267
VERSION     KCVT01007267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19712:8460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84792.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          123 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007268             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:16036:3772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007268
VERSION     KCVT01007268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16036:3772"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84793.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcatctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007269             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15445:6428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007269
VERSION     KCVT01007269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15445:6428"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84794.1"
                     /translation="CQQHNTYPLTF"
     J_segment       389..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          117 c          104 g           95 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 ggacattagt aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatgtattac gcatccaatt tggaaaatgg ggtcccatca aggttcagtg gtagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caagttatta
      361 ctgtcaacag cataatactt acccattgac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01007270             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16293:17177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007270
VERSION     KCVT01007270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16293:17177"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84795.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          119 c          124 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacctggagt ggtatttgca taagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007271             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16967:11388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007271
VERSION     KCVT01007271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16967:11388"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84796.1"
                     /translation="CLQYKTYPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          111 c          107 g          100 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcttc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 ggtattgctg gttatttaaa ttggtttcag aagaaaccag ggaaagcccc taagctcctg
      241 atccaagctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ataaaactta tccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007272             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14242:6285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007272
VERSION     KCVT01007272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14242:6285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84797.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccgggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcagact cccagactcc
      241 tcatctatgg ttcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca aaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007273             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16702:16507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007273
VERSION     KCVT01007273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16702:16507"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84798.1"
                     /translation="CLQGDTSPFTF"
     J_segment       388..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          116 c          111 g           97 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc tcagcgcctg
      241 atctatgctg catccacttt ggagaatggg gtcccgtcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg aagattttgc gacttattac
      361 tgtctacagg gtgatacttc cccgtttact ttcggcggag ggacccaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007274             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:9500:14835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007274
VERSION     KCVT01007274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9500:14835"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84799.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          124 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcgct cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007275             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:19669:9489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007275
VERSION     KCVT01007275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19669:9489"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84800.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgtgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtccag tcaaagcctt
      181 gtatacatca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 atttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01007276             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16636:17416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007276
VERSION     KCVT01007276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16636:17416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84801.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          114 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatctagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007277             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11294:19728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007277
VERSION     KCVT01007277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11294:19728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84802.1"
                     /translation="CQHGYGIPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagtccca gtcaggacac agcatggaca tgagggcccc cactcagctc
       61 ctggggttcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcca ggcgagtcag
      181 gccattagta ataatgtaat ctggtatcag caggaaccgg ggaaagcccc taagctcctg
      241 atctataagg catccacttt acaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcagcatg gttatggtat cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007278             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15095:20827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007278
VERSION     KCVT01007278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15095:20827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84803.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccatacgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagtagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007279             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16957:9266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007279
VERSION     KCVT01007279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16957:9266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84804.1"
                     /translation="CMQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagatt
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacact tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007280             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22770:13954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007280
VERSION     KCVT01007280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22770:13954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84805.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          106 a          127 c          117 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcaacagctt agcctggtac caacaaaaac ctgggcagcc
      241 tcccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 aggcagtggg tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt
      361 tgcagtttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007281             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23308:14820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007281
VERSION     KCVT01007281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23308:14820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84806.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatactctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007282             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8715:7775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007282
VERSION     KCVT01007282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8715:7775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84807.1"
                     /translation="CQQHNNYSPTF"
     J_segment       390..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          107 a          119 c          109 g           92 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tcctgctgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccaccct ccctgtctgc atctgtagga gacacagtca ccatcacttg tcgggcaagt
      181 cagggcatta gcaatgattt agtctggtat cagctgaaac cagggaaagc cccgaagccc
      241 ctgatctatt acgcatccaa tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      361 tactgtcaac agcataataa ttactctccc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01007283             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19357:17723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007283
VERSION     KCVT01007283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19357:17723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84808.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          100 a          115 c          117 g          100 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga caacctccta
      241 aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgat gatggtgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01007284             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5572:13370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007284
VERSION     KCVT01007284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5572:13370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84809.1"
                     /translation="CQQHNGYPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           91 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattacga atgatttagc ctggtatcaa cagaaaccag gtaaagcccc gaagcccctg
      241 atctattatg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagc ataatggata ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007285             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5572:13173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007285
VERSION     KCVT01007285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5572:13173"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84810.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gaggctgagg
      361 atgttgggct ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga ggtcaaacga g
//
LOCUS       KCVT01007286             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17947:4413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007286
VERSION     KCVT01007286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17947:4413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84811.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          103 a          125 c          119 g           89 t
ORIGIN      
        1 catggggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct
      241 cccaggctcc tcatctatgg tgcatccagt agggccactg gcatcccaga caggttcagt
      301 ggcagtgggt ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt
      361 gcagtttatt attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01007287             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24216:12474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007287
VERSION     KCVT01007287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24216:12474"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..438
                     /note="immunoglobulin light chain variable region"
     V_region        100..438
     V_segment       100..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84812.1"
                     /translation="CMQGLEYPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          117 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggta tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgcggat ggaaaaacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtt tagagtatcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007288             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14626:14598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007288
VERSION     KCVT01007288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14626:14598"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84813.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          119 c          118 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccctg cccgtcaccc ttagagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacag ctcttaattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007289             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:3314:15166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007289
VERSION     KCVT01007289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:3314:15166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84814.1"
                     /translation="CQQGYNTPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          117 c          114 g           88 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 gtccctgtct gcatctgtag gagacaaagt caccatcact tgccgagcca gtcagggtat
      181 tagcggctgg ttagcctggt atcagcagaa accagggaaa gcccctagac tcctgatcta
      241 taaggcgtcc actttggcaa gtggggtccc atcaaccttc agcggcagtg gatctggggc
      301 ggattacact ctcaccatca gcaggctgca gcctgaagat tttgcaactt attattgtca
      361 acagggttac aataccccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007290             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9464:8243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007290
VERSION     KCVT01007290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9464:8243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84815.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggag agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag tctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007291             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8657:16828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007291
VERSION     KCVT01007291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8657:16828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84816.1"
                     /translation="CQQGYSFPFTF"
     J_segment       381..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           95 a          122 c          105 g           98 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tgaacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcagtag tttaagctgg tatcagcaga aaccagggaa agcccctaac ctcctgatct
      241 ttagggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctcc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagtttcccc ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01007292             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:11612:14251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007292
VERSION     KCVT01007292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11612:14251"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..438
                     /note="immunoglobulin light chain variable region"
     V_region        103..438
     V_segment       103..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84817.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cgttgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccgggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007293             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:25025:12946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007293
VERSION     KCVT01007293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25025:12946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84818.1"
                     /translation="CLQYKSYPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          112 c          101 g          102 t
ORIGIN      
        1 acatggggag agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc ggacaagtca
      181 ggatattcac atttatttga attggtttca gcagaaacca gggaaagccc ctaaactcct
      241 gatctctgct gcatccagtt tggaaagtgg gttcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctacagcct gaagattttg caacttatta
      361 ttgtctacag tataaaagtt acccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007294             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5946:6061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007294
VERSION     KCVT01007294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5946:6061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84819.1"
                     /translation="CMQARDFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          125 c          120 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccattgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttcg atagtgagga aggaaacacc tatttggagt ggtacctgca gaggccaggc
      241 cagtctccac aggtcttgat ttatggggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgagaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagactttc cattcacttt cggccccggg
      421 accaaactgg acatcaaacg ag
//
LOCUS       KCVT01007295             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:12138:6430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007295
VERSION     KCVT01007295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12138:6430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84820.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgattcca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007296             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:5808:8621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007296
VERSION     KCVT01007296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:5808:8621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84821.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccaa ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007297             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8670:20667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007297
VERSION     KCVT01007297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8670:20667"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..425
                     /note="immunoglobulin light chain variable region"
     V_region        98..425
     V_segment       98..381
                     /gene="IGKV1-49"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84822.1"
                     /translation="CQQRIGYPYMYSF"
     J_segment       387..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          114 c          111 g          101 t
ORIGIN      
        1 acatgggggt tagacccagt ctggacgcag catggacatc agggtcctcg ctcagcttct
       61 cgggctcctg ctgctctggc tcccaggtgc cagatgtgac actcagttga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcgga caagtcagga
      181 cattagcagt tatttagcct ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctataaggcg tccagtttgc aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaggctgaa gattttgcag tttattactg
      361 tcaacagcgt attggttacc cgtacatgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01007298             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14771:19175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007298
VERSION     KCVT01007298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14771:19175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84823.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          121 c          124 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttcca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtc tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagcgt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007299             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20933:17297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007299
VERSION     KCVT01007299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20933:17297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..424
                     /note="immunoglobulin light chain variable region"
     V_region        104..424
     V_segment       104..388
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84824.1"
                     /translation="CLQYKSYPLTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>428
                     /gene="IGKC"
BASE COUNT          109 a          113 c          107 g           99 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcttgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag
      181 tcaggatatt agcacttatt taaattggtt tcagcagaaa ccagggaaag cccctagact
      241 cctgatctat actgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 gtctgggaca gaattcactc tcaccatcag cagcctgaag cctgaagatt ttgcaactta
      361 tcactgtcta cagtataaaa gttaccctct cactttcggc ggagggacca aggtggagat
      421 caaaagag
//
LOCUS       KCVT01007300             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:18387:7709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007300
VERSION     KCVT01007300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18387:7709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..383
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84825.1"
                     /translation="CQKYSSSPPVFSF"
     J_segment       393..424
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>430
                     /gene="IGKC"
BASE COUNT           97 a          123 c          118 g           92 t
ORIGIN      
        1 acatggggag agctgctcag ttaggaccca gagagaacca tggaaatccc agctcagctt
       61 ctcttcctcc tgctactgtg gctcccaggt accaccggac aagttatatt gactcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcagcttagc ctggtaccag cagaaacctg ggcgggcccc cagggtcctc
      241 atctatagtg tatccaacag ggccactggc atcccagaca ggttcagtgg cggtgggtct
      301 gggacagagt tcaccctcac catcagcagc ctggagcctg aagattttgc agtgtattac
      361 tgtcagaagt atagtagctc cccaccggtg ttcagttttg gccaggggac caaagtggag
      421 atcagacgag
//
LOCUS       KCVT01007301             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6070:11226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007301
VERSION     KCVT01007301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6070:11226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84826.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc cctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007302             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:17150:9677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007302
VERSION     KCVT01007302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17150:9677"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84827.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          118 c          114 g           90 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggaa aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagaa ttcactctca tcatcagtag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007303             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14550:16298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007303
VERSION     KCVT01007303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14550:16298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84828.1"
                     /translation="CMQSLEFPWTF"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           92 a          117 c          123 g          111 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttgggga gccggcctcc ttctcctgta ggtctagtca
      181 gagcctcttg gatgttgagg atggaaacac ctatttggac tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa atcagtagag tggaggctga
      361 ggatgttggg ttttatttct gcatgcaaag tctggagttt ccttggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007304             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13069:18167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007304
VERSION     KCVT01007304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13069:18167"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84829.1"
                     /translation="CIQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atacaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007305             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20015:3244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007305
VERSION     KCVT01007305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20015:3244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84830.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          125 c          111 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctctacct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agagaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007306             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21624:3029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007306
VERSION     KCVT01007306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21624:3029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84831.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          100 a          120 c          118 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggacta ctaatgctct ggctccctgg atccattggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggttcctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007307             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:23210:8994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007307
VERSION     KCVT01007307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23210:8994"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84832.1"
                     /translation="CMEALEFPYSF"
     J_segment       401..435
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac atcgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat gttgaggatg gaaacaccta tttggaatgg cacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tggaagctct agaatttccc tacagttttg gccaggggac
      421 caaactggag atcaagcgag
//
LOCUS       KCVT01007308             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:20718:10583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007308
VERSION     KCVT01007308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20718:10583"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84833.1"
                     /translation="CQQYNSDPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          105 a          113 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggatttgcaa cttatttctg
      361 tcaacagtat aacagtgacc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007309             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10254:18824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007309
VERSION     KCVT01007309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10254:18824"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84834.1"
                     /translation="CQQGYSYHPTF"
     J_segment       386..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>423
                     /gene="IGKC"
BASE COUNT           94 a          120 c          109 g          100 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga cttccttatg acgcagtctc
      121 cttcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattggcac taatttaaat tggtatcagc agagaccagg aaaagcccct aaactcctga
      241 tctatagggc ttccggtttg cagagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cagtctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac catcccactt tcggcggagg gaccaaggtg gagatccaac
      421 gag
//
LOCUS       KCVT01007310             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7337:22342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007310
VERSION     KCVT01007310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7337:22342"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84835.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007311             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:7129:15387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007311
VERSION     KCVT01007311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7129:15387"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84836.1"
                     /translation="CMQALDFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT          101 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga ttgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccaatg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggttcct ggagaagcca
      241 ggccagtctc cacaactctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg ggatttatta ctgcatgcaa gctctagact ttccgtggac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01007312             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:6833:16360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007312
VERSION     KCVT01007312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6833:16360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84837.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaactgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007313             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20483:8484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007313
VERSION     KCVT01007313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20483:8484"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84838.1"
                     /translation="CQQHNSYPPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          120 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat
      181 tagcaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 tttcgcatcc aatttggaaa ctggggtccc atcagggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat agttaccctc ccactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007314             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6917:18995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007314
VERSION     KCVT01007314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6917:18995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84839.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007315             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:17675:14106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007315
VERSION     KCVT01007315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17675:14106"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..396
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84840.1"
                     /translation="CQQNSNWPLTF"
     J_segment       397..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          103 a          124 c          120 g           89 t
ORIGIN      
        1 acatgggaga gctctgggga ggaactgctc agttaggacc cagagggaac catggaagcc
       61 ccagcacagc ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg
      121 atgacgcagt ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc
      181 agggccagtc agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct
      241 cccaggctcc tcatctttgg tacatccaac agggccactg gcatcccaga caggttcagt
      301 ggcagtgggt ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt
      361 gcagtttatt attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag
      421 gtggagatca aacgag
//
LOCUS       KCVT01007316             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7479:10283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007316
VERSION     KCVT01007316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7479:10283"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..413
                     /note="immunoglobulin light chain variable region"
     V_region        96..413
     V_segment       96..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84841.1"
                     /translation="CQQGYSYHPTF"
     J_segment       383..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>420
                     /gene="IGKC"
BASE COUNT           93 a          119 c          109 g           99 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgactt ccttatgacg cagtctcctt
      121 cctccctgtc cgcatctgta ggagacacag tcaccatcac ttgccaggcg agtcaagcca
      181 ttggcactaa tttaaattgg tatcagcaga gaccaggaaa agcccctaaa ctcctgatct
      241 atagggcttc cggtttgcag agtgggactc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcag tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tagttaccat cccactttcg gcggagggac caaggtggag atccaacgag
//
LOCUS       KCVT01007317             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:11883:4946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007317
VERSION     KCVT01007317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11883:4946"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84842.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          119 c          117 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccactgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaagtt tccaatcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagaatttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007318             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:10493:13889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007318
VERSION     KCVT01007318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10493:13889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84843.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          122 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agtagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac agattcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007319             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:16339:18121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007319
VERSION     KCVT01007319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16339:18121"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84844.1"
                     /translation="CQQYYSTPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          105 a          112 c          124 g          101 t
ORIGIN      
        1 acatgggggg agctacaaca ggcaggcagg ggcagcaaga tggtgtcaca gacccaagtc
       61 ttcatttccc tgttgctctg gatctctggt gcctgtgggg acattgtgat gacccagtcg
      121 ccagactccc tggctgtgtc tctgggagag agggtcacca tcaactgcaa gtccagccag
      181 agtcttttac gcgtctccaa caataggaac tacttagcct ggtatcagca gaaaccaggg
      241 caggctccta aattgctcat ttactgggca tctacccggg aattcgggat ccctaaccga
      301 ttcagtggca gtggatctgg gtcagatttc actctcacca tcagtggcct gcaggctgaa
      361 gatgtggcag tgtattactg tcagcagtat tatagcactc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007320             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18090:6308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007320
VERSION     KCVT01007320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18090:6308"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..433
                     /note="immunoglobulin light chain variable region"
     V_region        114..433
     V_segment       114..398
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84845.1"
                     /translation="CQQNSNWPLTF"
     J_segment       399..433
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>438
                     /gene="IGKC"
BASE COUNT          101 a          129 c          119 g           89 t
ORIGIN      
        1 acatggggga gagctctggg gaggaactgc tcagttagga cccagaggga accatggaag
       61 ccccagcaca gcttctcttc ctcctgctgc tctggctccc agataccacc ggagacatag
      121 tgctgacgca gtctccagcc accctgtctt tgtctccagg agaaagagcc accctctcct
      181 gcagggccag tcagagtgtc agcagcagtt tagcctggta ccagcagaaa cctgggcagg
      241 ctcccagact cctcatctat cgtgcatcca acagggccac tggcatccca tccaggttca
      301 gtggcagtgg gtctgggaca gagttcacac tcaccatcag cagcctggag cctgaagatg
      361 ttgcacttta ttattgtcag cagaacagta actggcctct cactttcggt ggagtgacca
      421 aggtggagat caagcgag
//
LOCUS       KCVT01007321             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:12578:14697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007321
VERSION     KCVT01007321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12578:14697"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84846.1"
                     /translation="CEQYNSLPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          111 c          101 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcaccagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtga
      361 acaatacaat agtttaccgt acacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007322             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22174:3825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007322
VERSION     KCVT01007322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22174:3825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84847.1"
                     /translation="CQQYNSLPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          108 c          111 g           98 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgccgggca agtcagggca
      181 ttagcgttta tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 attatgcaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgtaggt tattactgtc
      361 aacagtataa tagtttaccg ttcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007323             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:9960:15146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007323
VERSION     KCVT01007323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9960:15146"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..318
                     /note="immunoglobulin light chain variable region"
     V_region        119..318
     V_segment       119..280
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84848.1"
                     /translation="CMQALEFPWTF"
     J_segment       281..318
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           73 a           82 c           89 g           77 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      181 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      241 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      301 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007324             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:26509:6475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007324
VERSION     KCVT01007324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:26509:6475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..403
                     /note="immunoglobulin light chain variable region"
     V_region        82..403
     V_segment       82..365
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84849.1"
                     /translation="CQQYKRLPYTF"
     J_segment       366..403
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT          105 a          103 c          105 g           93 t
ORIGIN      
        1 acatggggac acagcatgga catgagggtc cccgctcagc tcctggggct cctgctgctc
       61 tggctcccag gtgccagatg tgacattcag atgacccagt ctccatcctc cctgtctgta
      121 tctgtaggag acagagtcac catcacttgc cgggcaagtg aggacattag cagttattta
      181 aattggtatc agcagaaacc ggggaaagcc cctaaggtcc tgatgtatta ttcaaaccgt
      241 ttggagagtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga attcactcta
      301 accatcagca gcctgcaacc tcaggatttt gcaacttatc actgtcaaca gtataaaagg
      361 ttaccgtaca cttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01007325             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20743:8827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007325
VERSION     KCVT01007325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20743:8827"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84850.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          125 c          116 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctct
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01007326             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17009:13575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007326
VERSION     KCVT01007326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17009:13575"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..417
                     /note="immunoglobulin light chain variable region"
     V_region        100..417
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84851.1"
                     /translation="CQQYDSDPYSF"
     J_segment       384..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>424
                     /gene="IGKC"
BASE COUNT          105 a          113 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattagga gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaaggccttg
      241 atctattaca catccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aggattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgtacagt tttggccagg ggaccagagt ggagatccaa
      421 cgag
//
LOCUS       KCVT01007327             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:21329:12003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007327
VERSION     KCVT01007327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21329:12003"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84852.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaggct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007328             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14236:19056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007328
VERSION     KCVT01007328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14236:19056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84853.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          122 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tgctgaggat ggaaacacct acttggaatg gtctttccag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007329             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14251:9710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007329
VERSION     KCVT01007329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14251:9710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..318
                     /note="immunoglobulin light chain variable region"
     V_region        118..318
     V_segment       118..281
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84854.1"
                     /translation="CMQAREFPLTF"
     J_segment       282..318
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           70 a           82 c           91 g           78 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagacgcc
      121 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      181 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      241 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      301 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007330             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:26488:7463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007330
VERSION     KCVT01007330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:26488:7463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..270
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84855.1"
                     /translation="CQQHDDSPRTF"
     J_segment       272..307
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>310
                     /gene="IGKC"
BASE COUNT           89 a           80 c           76 g           65 t
ORIGIN      
        1 acatgggcat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc
       61 agtcaggata ttaacacctg gttggcctgg tatcaacaga agccagggaa agcccctaag
      121 gtcctgatct ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaagt
      181 ggatctggga cagatttcac tctcaccatc aacagcctgc agcctgaaga tatcgcaaca
      241 tattactgtc aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa
      301 atcaaacgag
//
LOCUS       KCVT01007331             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13235:15451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007331
VERSION     KCVT01007331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13235:15451"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..347
                     /note="immunoglobulin light chain variable region"
     V_region        8..347
     V_segment       8..309
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <287..>319
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84856.1"
                     /translation="CMQALDFPWTF"
     J_segment       310..347
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>350
                     /gene="IGKC"
BASE COUNT           84 a           89 c           96 g           81 t
ORIGIN      
        1 acatggggac attgtgatga cccagactcc actctccctg cccgtcaccc ttggagagcc
       61 ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg gaaacaccta
      121 tttggaatgg ttcctgcaga agccaggcca gtctccacaa ctcttgattt atgaggtttc
      181 caaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac
      241 actgaaaatc agcagagtgg aggctgagga tgttgggatt tattactgca tgcaagctct
      301 agactttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01007332             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21009:14487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007332
VERSION     KCVT01007332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21009:14487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..335
                     /note="immunoglobulin light chain variable region"
     V_region        14..335
     V_segment       14..297
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <275..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84857.1"
                     /translation="CQQYNSLPYSF"
     J_segment       298..335
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>338
                     /gene="IGKC"
BASE COUNT           92 a           79 c           83 g           84 t
ORIGIN      
        1 acatgggaga tgtgacattg agatgaccca gtctccatcc tccctgtctg cttctgtagg
       61 agacagagtc accatcactt gccgggcaag tcagggcgtt aacgtttatt taaattggta
      121 tcaacagaaa ccggggaaag cccctaagcc cctgatcttt tatgcaaacc gtttggaacg
      181 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      241 cagcctgcaa cctgaagatt ttgcaagtta ttattgtcaa cagtataata gtttaccgta
      301 cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007333             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:7981:18093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007333
VERSION     KCVT01007333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7981:18093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..366
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84858.1"
                     /translation="CQQHDNMPLTF"
     J_segment       372..409
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT          103 a          111 c          111 g           87 t
ORIGIN      
        1 acatggggag tctcagacag catggacacg agggtccccg ctcagctcct ggggctcctg
       61 ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc atcctccctg
      121 tctgcatctg tgggagacag agtcaccatc acttgcaggg ccagtcaggg tattagcaac
      181 tggttggcct ggtatcaaca gaaaccaggg aaagccccta agctcctgat ctatagggca
      241 tggaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatccgg gacagatttc
      301 actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg tcaacagcat
      361 gataatatgc cgctcacttt cggtggaggg accaaggtgg acatcaaacg ag
//
LOCUS       KCVT01007334             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19527:18477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007334
VERSION     KCVT01007334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19527:18477"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..368
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84859.1"
                     /translation="CQQYDSDSLTF"
     J_segment       373..410
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>413
                     /gene="IGKC"
BASE COUNT          101 a          112 c          107 g           93 t
ORIGIN      
        1 acatggggag tcaggacaca gcatggacat gagggtcccc gctcagctcc taggactcct
       61 gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc catcctccct
      121 gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg acattcgcag
      181 ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga tctattacgc
      241 gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg ggacagaatt
      301 cactctcacc atcagcagcc tgcagcctga agattttgca acttattact gtcaacagta
      361 tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007335             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:18307:5859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007335
VERSION     KCVT01007335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18307:5859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84860.1"
                     /translation="CLQGYNIPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          109 c          109 g           97 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagttgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc gcctgatcta
      241 tgctgtgtcc agtttggaag gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcgactt attactgtct
      361 acagggttat aatatcccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007336             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10160:9672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007336
VERSION     KCVT01007336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10160:9672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84861.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctcccc gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007337             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:16047:16261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007337
VERSION     KCVT01007337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16047:16261"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84862.1"
                     /translation="CMQALDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          127 c          113 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 ccccctccct gcccgtcacc cttggagagg cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttcga tactgaagaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agactccaca gctcttgatt tatcaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggact ttattactgc atgcaggctc tagactttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007338             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:12751:24226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007338
VERSION     KCVT01007338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12751:24226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84863.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          123 c          120 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg atcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007339             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22040:14688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007339
VERSION     KCVT01007339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22040:14688"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84864.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007340             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9525:9194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007340
VERSION     KCVT01007340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9525:9194"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..438
                     /note="immunoglobulin light chain variable region"
     V_region        100..438
     V_segment       100..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84865.1"
                     /translation="CMQGLEYPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          101 a          117 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggaa tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgcggat ggaaaaacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ctattactgc atgcaaggtt tagagtatcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007341             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15199:15628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007341
VERSION     KCVT01007341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15199:15628"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84866.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g           93 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcagcaga acccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tccggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01007342             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16232:11857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007342
VERSION     KCVT01007342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16232:11857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84867.1"
                     /translation="CMQYTHMPLTF"
     J_segment       401..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           99 a          122 c          120 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggat ccagtgggga tactgtgatg acccagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaagat ggaaacacct atttggattg gtacctgcaa aagccgggcc
      241 agtcgccaca gcccttgatt tacgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaatata cacacatgcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcgaacga g
//
LOCUS       KCVT01007343             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7433:16238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007343
VERSION     KCVT01007343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7433:16238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84868.1"
                     /translation="CQQHNVYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          120 c          109 g           91 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac caatgattta gcctggtatc agcagagacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgtt taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007344             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9778:13265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007344
VERSION     KCVT01007344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9778:13265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84869.1"
                     /translation="CQQYNSLPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          104 g          101 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgcc ggacaagtca
      181 ggacattgtt acttatttaa attggtatca gcagaaaccg gggaaagccc ctaagctcct
      241 gatctattat ggaaaccgtt tgcatgatgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggaccgaa ttcactctcg ccatcagcag cctgcaacct gaggattttg caatttattt
      361 ctgtcaacag tataatagtt taccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01007345             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9353:14731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007345
VERSION     KCVT01007345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9353:14731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84870.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007346             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:11055:10127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007346
VERSION     KCVT01007346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11055:10127"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84871.1"
                     /translation="CLQYRSYPYNF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          109 a          110 c          103 g           96 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcaggatatt
      181 agcagttatt taaattggtt tcagaagaaa ccagggaaag cccctaagct cctgatccaa
      241 gctgcatcca gtttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcta
      361 cagtatagaa gttacccgta caattttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007347             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22147:8131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007347
VERSION     KCVT01007347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22147:8131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84872.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007348             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:7010:12244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007348
VERSION     KCVT01007348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7010:12244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84873.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          111 a          117 c          109 g           87 t
ORIGIN      
        1 atggggagga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagccac
      181 gatataaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcagtgg aagtggatct
      301 gggacagatt tcactctcag catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007349             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:23733:15423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007349
VERSION     KCVT01007349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23733:15423"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84874.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          129 c          120 g           86 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gctgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcaccccag gcaggttcag
      301 tggcactggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaacagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007350             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:27601:10996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007350
VERSION     KCVT01007350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:27601:10996"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84875.1"
                     /translation="CMQSLEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           92 a          118 c          119 g          111 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggggagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat gttgaggatg gaaacaccta tttggactgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtctgaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggttt tatttctgca tgcaaagtct ggagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007351             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:25467:11472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007351
VERSION     KCVT01007351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25467:11472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84876.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcacaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007352             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18765:14046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007352
VERSION     KCVT01007352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18765:14046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84877.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007353             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13854:16313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007353
VERSION     KCVT01007353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13854:16313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84878.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgctt gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatctggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007354             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18372:4213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007354
VERSION     KCVT01007354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18372:4213"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..359
                     /note="immunoglobulin light chain variable region"
     V_region        20..359
     V_segment       20..322
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84879.1"
                     /translation="CMQALEFPWTF"
     J_segment       323..359
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           84 a           91 c          103 g           84 t
ORIGIN      
        1 acatggggga tccagtgggg acattgtgat gacccagact ccactctccc tgcccgtcac
       61 ccttggagag ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga
      121 tggaaacacc tatttggatt ggtacctgca gaagccaggc cagtctccac acctcttgat
      181 ttatgaggtt tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga
      241 cactgatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg
      301 catgcaagct ctagagtttc cttggacgtt cggccaaggg accaaggtgg aaatcaaacg
      361 ag
//
LOCUS       KCVT01007355             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20781:3636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007355
VERSION     KCVT01007355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20781:3636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84880.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          124 g          105 t
ORIGIN      
        1 acagggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007356             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:22214:13139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007356
VERSION     KCVT01007356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22214:13139"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84881.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          120 c          117 g          106 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc actggggaca ttgtgctgac ccagactcca
      121 ctctccctgc ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagaac
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aatcgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga gcctgaggat
      361 gttggggttt attactgcat gcaagctcta gaatttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01007357             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6795:20047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007357
VERSION     KCVT01007357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6795:20047"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84882.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagacac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcggtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007358             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:11463:18092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007358
VERSION     KCVT01007358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11463:18092"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..329
                     /note="immunoglobulin light chain variable region"
     V_region        8..329
     V_segment       8..291
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84883.1"
                     /translation="CQQYDSLPWTF"
     J_segment       292..329
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>332
                     /gene="IGKC"
BASE COUNT           92 a           84 c           80 g           76 t
ORIGIN      
        1 acatggggac attcagatga cccagtctcc atcctccctg tctgcatctg taggagacag
       61 agtcaccatc acttgccggg caagtcaggg cattagcaat tatttaaatt ggtatcagga
      121 gaaaccgggg aaagccccta agcccctgat ctattataca aaccgtttgg aaagtggggt
      181 cccatcaagg ttcagcggca gtagatctgg gacagaattc actctcacca tcagcagcct
      241 gcaacctgag gattttgcaa cttactactg tcaacagtat gattctttac cgtggacgtt
      301 cggccaaggg accaaggtgg acatcaaacg ag
//
LOCUS       KCVT01007359             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12495:15587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007359
VERSION     KCVT01007359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12495:15587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84884.1"
                     /translation="CQQYDSFPLTF"
     J_segment       387..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          117 c          110 g           97 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtgggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagt aattatttaa attggtatca gcagaaaccg gggaaagccc ctaagctcct
      241 gatctattat ggaaaccgtt tgggaagcgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaggattttg cgacttatca
      361 ttgtcagcag tatgatagtt tccccctcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01007360             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:6254:9595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007360
VERSION     KCVT01007360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6254:9595"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84885.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          104 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acgtccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01007361             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19521:15646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007361
VERSION     KCVT01007361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19521:15646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..385
                     /note="immunoglobulin light chain variable region"
     V_region        64..385
     V_segment       64..347
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84886.1"
                     /translation="CQQYNSDPFTF"
     J_segment       348..385
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           97 a          108 c           93 g           90 t
ORIGIN      
        1 acatgggggg tccccgctca gctcctagga ctcctgctgc tctgtctccc aggtgccaaa
       61 tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg agacagagta
      121 accatcactt gtcgggcgag tcaggacata agaagttatt tagcgtggta tcagcagaaa
      181 ccaggcaaag ccccgaagcc cttgatctat tacgcatccg ttttggaaag tggggtccca
      241 tcaaggttca gtggcagtgg atctgggaca gaattcactc tcaccatcag cagtctgcag
      301 cctgaggatt ttgcaactta ttactgtcaa cagtataaca gtgacccatt cactttcggc
      361 cccgggacca aactggatac caaacgag
//
LOCUS       KCVT01007362             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9902:13288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007362
VERSION     KCVT01007362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9902:13288"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84887.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          113 c          111 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccaggtg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg aaggccttaa
      241 tctattacgc gaccattttg gaaagtgggg tcccatctag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttatttct
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007363             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:18908:19089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007363
VERSION     KCVT01007363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18908:19089"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84888.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 agtccactct ccctgtccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag atttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcac agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccgctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01007364             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20287:23604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007364
VERSION     KCVT01007364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20287:23604"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84889.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gtattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acctattact
      361 gtcaacagta tgacagtgat ccgttcactt tcggtggggg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01007365             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14728:6075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007365
VERSION     KCVT01007365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14728:6075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84890.1"
                     /translation="CQQYNSDPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          113 c          112 g           94 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccaggtgac ccagtctccg
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 gttagaagtt atttagcgtg gtatcagctg agaccaggga aagccccgaa ggccttaatc
      241 tattacgcga ccattttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgagg attttgcaac ttatttctgt
      361 caacagtata acagtgaccc gtacactttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007366             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:4871:10944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007366
VERSION     KCVT01007366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4871:10944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84891.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          124 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tacttggaat ggtatttcca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaagcggg cctctggagt cgcagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007367             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19520:6303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007367
VERSION     KCVT01007367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19520:6303"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84892.1"
                     /translation="CQQYKNLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          108 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgtatct gtaggagaca gagtcaccat cacttgccgg acaagtgagg
      181 acattagcag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tgtattattc aaaccgtttg gagagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctaacc atcagcagcc tgcaacctga ggattttgca acttatcact
      361 gtcaacagta taagaactta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007368             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12528:11052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007368
VERSION     KCVT01007368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12528:11052"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84893.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007369             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:4989:15920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007369
VERSION     KCVT01007369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4989:15920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84894.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          116 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattgc
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007370             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14831:8625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007370
VERSION     KCVT01007370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14831:8625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84895.1"
                     /translation="CQQGDSYPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          106 a          112 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctactctggc tcccaggtgc cagatgtgac attcagatgt cccagtctcc
      121 ttcctccctg tctgcatctg tgggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagagat tatttaaatt ggtatcagca gcaaccgggg aaagccccta aactcctgat
      241 gtattatgca aacagtctgg caagtggagt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc agtctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagggt gacagttatc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01007371             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:8834:19887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007371
VERSION     KCVT01007371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8834:19887"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84896.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 gtccactctc cctgtccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgaga tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaca gtgggggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007372             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5482:17200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007372
VERSION     KCVT01007372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5482:17200"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84897.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          125 c          113 g           85 t
ORIGIN      
        1 acatgggggg ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007373             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:23485:4022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007373
VERSION     KCVT01007373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23485:4022"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84898.1"
                     /translation="CMQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacgggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tacaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007374             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12080:10847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007374
VERSION     KCVT01007374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12080:10847"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84899.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           96 a          123 c          119 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtgtatatca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaaccccca
      241 aggcgcctaa tttatgaggt ctctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaacgtg
      421 gagatcaaac gag
//
LOCUS       KCVT01007375             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18309:14202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007375
VERSION     KCVT01007375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18309:14202"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84900.1"
                     /translation="CQQHDNFPYIF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          115 c          102 g           92 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcaacatat
      181 tagcgactgg ttggcctggt atcaacagaa accagggaaa gcccctaagc tcctgatcta
      241 tcgggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagctttca gcctgaagat atcgcaacat attactgtca
      361 acagcatgat aatttcccgt acatttttga ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01007376             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13492:14242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007376
VERSION     KCVT01007376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13492:14242"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84901.1"
                     /translation="CQQYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          103 a          112 c          109 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc aatctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtctatat ttaaattggt atcaacagaa accggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 gcagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01007377             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:22462:8615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007377
VERSION     KCVT01007377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22462:8615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84902.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01007378             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:14369:16084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007378
VERSION     KCVT01007378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14369:16084"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84903.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          101 a          122 c          117 g           87 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcagcagctt agcctggtac cagcagaaac ctgggcaggc tcccaggctc
      241 ctcatctttg gtgcatccaa cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01007379             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8570:15584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007379
VERSION     KCVT01007379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8570:15584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84904.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          105 a          125 c          112 g           85 t
ORIGIN      
        1 acatggggag aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gcaacagctt agcctggtac caacaaaaac ctgggcagcc tcccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag aggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgaagatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01007380             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:17665:4945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007380
VERSION     KCVT01007380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17665:4945"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84905.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcactat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007381             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:16952:13541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007381
VERSION     KCVT01007381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16952:13541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84906.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          119 c          114 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtcg
      181 gactgttggc agcgccttag cctggtacca gcagaaacct gggcagactc acaaactcct
      241 catttatggt gcatccaaca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcagtag tccggagcct gaggatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007382             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12939:13915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007382
VERSION     KCVT01007382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12939:13915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84907.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          117 c          124 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggg
      241 cagtctccac aactcttgat ttatgaggtt tccgaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctggactttc cgtggacgtt cggccaaggg
      421 accaaggtgg aagtcaaacg ag
//
LOCUS       KCVT01007383             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4398:13859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007383
VERSION     KCVT01007383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4398:13859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84908.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgagaat ggaaacacct atgtggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007384             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19260:10497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007384
VERSION     KCVT01007384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19260:10497"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84909.1"
                     /translation="CQQYDKSPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          117 c          114 g           85 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagggt caccatcact tgcagagcca gtcagggtat
      181 cagcaactgg ttggcctggt atcaacagaa accagggaga gcccctaacc tcctgatgta
      241 tagggcgtcc aatttgcaag gaggggtccc atcaaggttc agaggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaggat gtcgctacat attactgtca
      361 acagtatgat aagtcccctc cgacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007385             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:24895:9672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007385
VERSION     KCVT01007385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24895:9672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..412
                     /note="immunoglobulin light chain variable region"
     V_region        91..412
     V_segment       91..374
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84910.1"
                     /translation="CLQYKTYPYSF"
     J_segment       375..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>415
                     /gene="IGKC"
BASE COUNT          103 a          109 c          104 g           99 t
ORIGIN      
        1 acatggggac agtcaggaca cagcatggac atgagggccc ccgctcatct cctagggctc
       61 ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc tccatcttcc
      121 ctgtctgctt ctgtaggaga cactgtcacc atcacttgcc gggcaagtca gggtattgct
      181 ggttatttaa attggtttca gaagaaacca gggaaagccc ctaagctcct gatccaagct
      241 gcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc tgggacagaa
      301 ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta ctgtctacag
      361 tataaaactt atccgtacag ttttggccag gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01007386             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22245:12364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007386
VERSION     KCVT01007386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22245:12364"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84911.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          123 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagt cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtgcctgcag aagccaggcc
      241 agtctccaca gctcctgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattcctgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007387             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:25011:13528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007387
VERSION     KCVT01007387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25011:13528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..436
                     /note="immunoglobulin light chain variable region"
     V_region        115..436
     V_segment       115..398
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84912.1"
                     /translation="CQQHNTYPYTF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          112 a          123 c          107 g           97 t
ORIGIN      
        1 acatggggac acacttcatg taggagtcag aaccactcag gacacagcat ggacatgagg
       61 gtccccgctc agctcctggg gctcctgctg ctctggctcc caggtgccag atgtgacatc
      121 cagatgaccc agtctccatc ctccctgtct gcatctgtag gagacacagt caccatcact
      181 tgtcgggcaa gtcagggcat tagtaatgat ttagcctggt atcagcagaa accagggaaa
      241 gccccgaagc ccctgatctt ttacgcatcc aatttggaaa gtggggtccc atcaaggttc
      301 agcggcagtg gatctgggac agatttcact ctcaccatca gcagcctgca gcctgaagat
      361 tttgcaactt attactgtca acaacataat acttacccgt acacttttgg ccaggggacc
      421 aacgtggaga tcaaacgag
//
LOCUS       KCVT01007388             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12569:10910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007388
VERSION     KCVT01007388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12569:10910"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84913.1"
                     /translation="CHQYNNLPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          114 c          104 g           98 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tgtctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattaa catttattta aattggtatc agcagaaacc ggggaaagcc cctaagctcc
      241 tgatctatta tgcaaatcgt ttggaaactg gggtcccgtc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcaaca gcctgcaacc cgaagatttt gcaacttatt
      361 actgtcacca gtataataat ttaccactca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007389             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8088:6610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007389
VERSION     KCVT01007389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8088:6610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84914.1"
                     /translation="CQQYNSLPWTF"
     J_segment       384..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          113 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgagctgg ctcccaggtg ccagatgtga cattacgatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag ttttttaaat tggtatcaac tgagaccggg gaaagcccct aagctcctga
      241 tctattatgc aaaccgtttg gacagtgggg tcccatcaag gttcagcggc ggtggatctg
      301 ggccagaatt cactctcacc atcagcagcc tgcaacctga ggattttgcc acttattact
      361 gtcaacagta taatagttta ccttggacgt tcggccaagg ggccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007390             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22394:4068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007390
VERSION     KCVT01007390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22394:4068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84915.1"
                     /translation="CQQGHTYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          121 c          105 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaagact ttaagttggt atcagcagaa accagggaaa gcccctaatc tcctgatcta
      241 tagggcatcc agtttgcaag gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggtcat acttacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007391             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20749:12692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007391
VERSION     KCVT01007391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20749:12692"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84916.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          121 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gaaacctggg caggctccca gactcctcat
      241 gtatggtgca tccaacaggg ccactggcat cccagacagg ttcagtggca gtgggtctgg
      301 gacagagttc actctcacca tcagcagcct ggagcctgaa gatgttgcac tttattattg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007392             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12607:8074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007392
VERSION     KCVT01007392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12607:8074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84917.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          113 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007393             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13935:15298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007393
VERSION     KCVT01007393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13935:15298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84918.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgttctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007394             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21195:10493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007394
VERSION     KCVT01007394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21195:10493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84919.1"
                     /translation="CQQHADSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          119 c          104 g           87 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataattgg ttggcctggt atcaacagaa accaggaaaa gcccctaacc tcctgatcta
      241 taggacatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgct gattcccctc ggacgttcgg ccaagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007395             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:10938:7093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007395
VERSION     KCVT01007395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10938:7093"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84920.1"
                     /translation="CQQHADSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          120 c          106 g           88 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagccacga
      181 tataaataat tggttggcct ggtatcaaca gaaaccagga aaagccccta acctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatttcgcaa catattactg
      361 tcaacagcat gctgattccc ctcggacgtt cggccaaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007396             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18878:6786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007396
VERSION     KCVT01007396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18878:6786"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84921.1"
                     /translation="CLQGYSAPFTF"
     J_segment       385..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>425
                     /gene="IGKC"
BASE COUNT          102 a          118 c          108 g           97 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgctt cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagaaacca ggaaaaactc ctcagcgcct
      241 gatctatgct gcatccagtt tggagagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tggcacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cagcttatta
      361 ctgtctacag ggttatagtg ccccattcac tttcggcccc gggaccaaac tggatatcaa
      421 aagag
//
LOCUS       KCVT01007397             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16707:8699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007397
VERSION     KCVT01007397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16707:8699"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84922.1"
                     /translation="RQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          127 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 accgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007398             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22337:12684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007398
VERSION     KCVT01007398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22337:12684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84923.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcctgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007399             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4073:10995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007399
VERSION     KCVT01007399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4073:10995"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84924.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgat gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007400             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15086:10314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007400
VERSION     KCVT01007400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15086:10314"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..413
                     /note="immunoglobulin light chain variable region"
     V_region        99..413
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84925.1"
                     /translation="CQQGYNYPWTF"
     J_segment       383..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>423
                     /gene="IGKC"
BASE COUNT          101 a          117 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taatttaaat tggtatctcc agaaaccagg gaaaggccct aaactcctga
      241 tctctagggc atccagtttg caaagtggga ttccctcgcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttataattac ccgtggacgt tcggccaagg gaccaaggtg gaagccaaac
      421 gag
//
LOCUS       KCVT01007401             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8890:16927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007401
VERSION     KCVT01007401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8890:16927"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84926.1"
                     /translation="CQQYDSDPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcagacacag cttggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattagcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctatttcgca tccactttgg aaagtggcgt cccatcaagg ttcagcggca gtggatctgg
      301 gacagagttc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007402             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:7086:14921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007402
VERSION     KCVT01007402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7086:14921"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84927.1"
                     /translation="CQQYNTLITF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          111 c          105 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cgcttgccgg gcaagtcagg
      181 acataagtaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttatttct
      361 gtcaacagta taacacttta atcactttcg gcgggggaac caaggtggag atcaaacgag
//
LOCUS       KCVT01007403             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12663:9673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007403
VERSION     KCVT01007403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12663:9673"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84928.1"
                     /translation="CMQARDFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          125 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggaa ggaaacacct atttggagtg gtacctgcag aggccaggcc
      241 agtctccaca ggtcttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgagaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagactttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01007404             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14023:5613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007404
VERSION     KCVT01007404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14023:5613"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84929.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          117 c          104 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaaac ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007405             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16384:13825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007405
VERSION     KCVT01007405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16384:13825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84930.1"
                     /translation="CMQSLEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          117 c          123 g          109 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggggag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atgttgagga tggaaacacc tatttggact ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagtagagt ggaggctgag
      361 gatgttgggt tttatttctg catgcaaagt ctggagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007406             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11206:14856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007406
VERSION     KCVT01007406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11206:14856"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84931.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          118 g          104 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctggag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007407             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9232:4695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007407
VERSION     KCVT01007407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9232:4695"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84932.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg cttcctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcatgga tagtggggat gtaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acggatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtacagtttt ggccagggga
      421 ccagagtgga gatcaaacga g
//
LOCUS       KCVT01007408             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:15372:9883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007408
VERSION     KCVT01007408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15372:9883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84933.1"
                     /translation="CQQDYSWPPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tgtcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcatcttag cctggtacca ccagaaacct gggcaggctc ccaagtccct
      241 catctatggt gcaaccagta gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gcgtttatta
      361 ctgtcagcag gattatagct ggccacccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007409             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15780:9131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007409
VERSION     KCVT01007409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15780:9131"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84934.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..439
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg tatgcaagct ctagagtttc cattcacctt cggccccggg
      421 accaaagtgg atatcaaacg ag
//
LOCUS       KCVT01007410             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14550:18108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007410
VERSION     KCVT01007410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14550:18108"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84935.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          123 c          116 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acaaccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcacc agaagccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gacatcaaac gag
//
LOCUS       KCVT01007411             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22769:8999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007411
VERSION     KCVT01007411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22769:8999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84936.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007412             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10418:6459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007412
VERSION     KCVT01007412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10418:6459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84937.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcag
      421 acgag
//
LOCUS       KCVT01007413             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11539:6455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007413
VERSION     KCVT01007413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11539:6455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84938.1"
                     /translation="CEQYNSLPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          112 c          103 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cgttaacatt tatttaaatt ggtatcacca gaaaccgggg aaagccccta agctcctgat
      241 ctattataca aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tgaacaatac aatagtttac cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007414             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15396:5549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007414
VERSION     KCVT01007414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15396:5549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..409
                     /note="immunoglobulin light chain variable region"
     V_region        91..409
     V_segment       91..373
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84939.1"
                     /translation="CYQHSRGWAF"
     J_segment       374..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           97 a          120 c          114 g           81 t
ORIGIN      
        1 acatggggag gttagtaccc agaaggaacc atggaagccc cagctcagct tctctgcctt
       61 ctgctactct ggctcccagg taccaccgga caaattatat tgacacagtc tccagccacc
      121 ctgtctttgg caccagggga aagagccact ctctcctgca gggccagtga gaatgttggc
      181 agctacttag cctggtacca gcagaaccct gggcaggctc ccaggctcct cgtccacagt
      241 gcgtccagca gggccactga catcccagac aggttcagtg gcagtgggtc tcggacagag
      301 ttcaccctca ccatcagcag tctggagcct gaagatgttg gagtctatta ctgctatcaa
      361 catagcaggg ggtgggcgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007415             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22797:23889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007415
VERSION     KCVT01007415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22797:23889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84940.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          113 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgtttgggt ttattactgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007416             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8275:18749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007416
VERSION     KCVT01007416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8275:18749"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84941.1"
                     /translation="CQQYNSDPFTF"
     J_segment       382..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          117 c          102 g           95 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtaaccatc acttgtcggg cgagtcagga
      181 cataagaagt tatttagcgt ggtatcagca gaaaccaggc aaagccccga agcccttgat
      241 ctattacgca tccgttttgg aaagtggggt cccatcaagg ttcagtggca gtggatctgg
      301 gacagaattc actctcacca tcagcagtct gcagcctgat gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cattcacttt cggccccggg accaaactgg ataccaaacg
      421 ag
//
LOCUS       KCVT01007417             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9213:21216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007417
VERSION     KCVT01007417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9213:21216"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84942.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtaga aatcgaacga g
//
LOCUS       KCVT01007418             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16148:6757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007418
VERSION     KCVT01007418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16148:6757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84943.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01007419             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:16648:5861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007419
VERSION     KCVT01007419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16648:5861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84944.1"
                     /translation="CLQGYTIPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          114 c          109 g           95 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggtaggag acagagtcac catcacttgc cggacaagtc
      181 agggcattag cgattattta agttggtatc agcagaaacc aggaaaagct cctaagcgcc
      241 tgatccatgc tgtatccagt ttggaaagtg gggccccatc aaggttcagc ggcagtggat
      301 ctgaaacaga gttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtctaca gggttatact atcccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01007420             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16665:3487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007420
VERSION     KCVT01007420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16665:3487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84945.1"
                     /translation="CQQHDNSPPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          115 c          111 g           92 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg gcacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctccaggtg ccagatgtga catccagatg acccagtctc
      121 cttcctccct gtctgcatct ataggcgaca gagtcaccat cacttgcaga gccagtcagg
      181 gtattagcga ctggttggcc tggtatcaac agaaaccagg gaaagcccct aaactcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcaggctga agatttcgca acatatttct
      361 gtcaacagca tgataattcc cctcccactt tcggtggagg gactaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007421             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:9496:10395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007421
VERSION     KCVT01007421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9496:10395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84946.1"
                     /translation="CQQYDSDPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          100 a          114 c          111 g           93 t
ORIGIN      
        1 atgggggaga cccagccagg acacagcttg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag tcagggcatt
      181 agcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc cttgatctat
      241 ttcgcatccg ttttggaaag tggcgtccca tcaaggttca gcggcagtgg atctgggaca
      301 gagttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 cagtatgaca gtgacccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007422             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:16193:9135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007422
VERSION     KCVT01007422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16193:9135"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..300
                     /note="immunoglobulin light chain variable region"
     V_region        6..300
     V_segment       6..263
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <240..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84947.1"
                     /translation="CMQALEFPLTF"
     J_segment       264..300
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>303
                     /gene="IGKC"
BASE COUNT           75 a           68 c           87 g           73 t
ORIGIN      
        1 acatggggga tcacgactcc atctcctgca ggtctagtca gagcctcttg gatagtgagg
       61 atggaaacac ctatttggaa tggtacctgc agaaaccagg ccagtctcca cgactcttga
      121 tttatgaggt ttccaaccgg gcctctggag tcccagacag gttcagtggc agtgggtcag
      181 acactgattt cacactgaaa atcagcagag tggaggctga ggatgttggg gtttattact
      241 gcatgcaagc tctagagttt cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      301 gag
//
LOCUS       KCVT01007423             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7581:15110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007423
VERSION     KCVT01007423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7581:15110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..432
                     /note="immunoglobulin light chain variable region"
     V_region        93..432
     V_segment       93..395
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84948.1"
                     /translation="CMQALEFPWTF"
     J_segment       396..432
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT           93 a          117 c          123 g          102 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgtg gggacattgt gatgacccag actccagtct
      121 ccctgcccgt caccctggga gagccggcct ccatctcctg caggtctagt cagagcctct
      181 tggatagtga ggatggaaac acctatttgg aatggcacct gcagaggcca ggccagtctc
      241 cacagctctt gatttatgag gtttcctatc gggcctctgg agtcccagac aggttcagtg
      301 gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg
      361 gggtttatta ctgcatgcaa gctctagagt tcccttggac gttcggccaa gggaccaagg
      421 tggagatcaa acgag
//
LOCUS       KCVT01007424             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:18897:20894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007424
VERSION     KCVT01007424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18897:20894"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84949.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          106 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg gtccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatggtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007425             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:22534:8404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007425
VERSION     KCVT01007425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22534:8404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84950.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007426             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:18315:8642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007426
VERSION     KCVT01007426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18315:8642"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84951.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          126 c          111 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tggacaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007427             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:19903:17198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007427
VERSION     KCVT01007427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19903:17198"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84952.1"
                     /translation="CLQESNWSYSF"
     J_segment       385..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          120 c          121 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tagtaccgga gaaatagtgg tgacacagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcaaa agcaggttag cctggtacca gcagaaacct gggcaagctc ccaggctcct
      241 catgtatgat gcgtccagca gggccactgg catcccagac aggttcactg gcagcgggtc
      301 tgggccagag ttcactctca ccatcagcag cctggagcct gaagatgttg cggtttattt
      361 ctgtcttcag gagagtaact ggtcgtacag ctttggccag ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01007428             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:2189:15873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007428
VERSION     KCVT01007428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:2189:15873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..331
                     /note="immunoglobulin light chain variable region"
     V_region        8..331
     V_segment       8..293
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84953.1"
                     /translation="CMQALEFPFTF"
     J_segment       294..331
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           77 a           89 c           89 g           79 t
ORIGIN      
        1 acatgggaga ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc
       61 aggtctagtc agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg
      121 cagaagccag gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga
      181 gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgat aatcagcaga
      241 gtggaggctg aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccattcacc
      301 ttcggccccg ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01007429             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:17109:9536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007429
VERSION     KCVT01007429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17109:9536"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84954.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           93 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcgtctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01007430             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16118:18296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007430
VERSION     KCVT01007430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16118:18296"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84955.1"
                     /translation="CQQNSNRPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          122 c          117 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaattgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagtagttta gcctggtacc agcagagacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcgtccagc agggccactg acatcccaga cagattcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc cgaagatgtt gcagtttatt
      361 tttgtcagca gaatagtaat cggccgtaca cttttggcca ggggaccaaa gtggagatca
      421 aacgag
//
LOCUS       KCVT01007431             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7986:3899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007431
VERSION     KCVT01007431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7986:3899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84956.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc catatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaggc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007432             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23070:12741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007432
VERSION     KCVT01007432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23070:12741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84957.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          118 c          110 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccatatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtggagg gaccaaggtg gacatcaaac
      421 gag
//
LOCUS       KCVT01007433             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:15501:6801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007433
VERSION     KCVT01007433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15501:6801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..284
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <262..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84958.1"
                     /translation="CQHSFRTPYSF"
     J_segment       285..322
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>325
                     /gene="IGKC"
BASE COUNT           83 a           84 c           81 g           77 t
ORIGIN      
        1 acatgggaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcaat
       61 gtcacttgca gggctagtga gagcgttagc accaaattac attggtatca gcagaaacca
      121 gggaaagccc ctaagctcct gatctttgct gcgtccactt tgcaaagtgg ggtcccatca
      181 aggttcagcg gcagtggatc tggaacagat ttcactctca ccatcagcag cctgcagcct
      241 gaagatgtcg caacttttta ctgtcagcat agttttcgta ccccgtacag ttttggccag
      301 gggaccaaag tggagatcaa acgag
//
LOCUS       KCVT01007434             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15391:13775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007434
VERSION     KCVT01007434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15391:13775"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84959.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          122 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggagtgg cacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgacgtttc cagccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccc tacagttttg gccaggggac
      421 caaagtggag atcaaacgag
//
LOCUS       KCVT01007435             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14104:2120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007435
VERSION     KCVT01007435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14104:2120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84960.1"
                     /translation="CMQSLEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          117 c          121 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tgttgatgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggtt ttatttctgc atgcaaagtc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007436             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:25902:15812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007436
VERSION     KCVT01007436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25902:15812"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84961.1"
                     /translation="CLQGYNIPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          109 c          108 g           97 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagttgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagaa accaggaaaa gctcctaagc gcctgatcta
      241 tgctgtgtcc agtttggaag gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcgactt attactgtct
      361 acagggttat aatatcccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007437             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:18396:13109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007437
VERSION     KCVT01007437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18396:13109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84962.1"
                     /translation="CLQGYITPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          113 c          112 g           99 t
ORIGIN      
        1 actggggagg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacttccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tgcaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ctgtctacag ggttatatta ccccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007438             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:20869:5940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007438
VERSION     KCVT01007438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20869:5940"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..380
                     /note="immunoglobulin light chain variable region"
     V_region        41..380
     V_segment       41..343
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <320..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84963.1"
                     /translation="CMQALEFPLTF"
     J_segment       344..380
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>383
                     /gene="IGKC"
BASE COUNT           86 a           97 c          107 g           93 t
ORIGIN      
        1 acatgggctg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
       61 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      121 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      181 ccagtctcca cagctcttga tttatgaggt ttccatacgg gcctctggag tcccagacag
      241 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagtagag tggaggctga
      301 ggatgttggg atttattact gcatgcaagc tctagagttt cctctcactt tcggcggagg
      361 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007439             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:26333:12217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007439
VERSION     KCVT01007439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26333:12217"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84964.1"
                     /translation="CQQYNSDPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          116 c          106 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtaac catcacttgt cgggcgagtc
      181 aggacataag aagttattta gcgtggtatc agcagaaagc aggcaaagcc ccgaagccct
      241 tgatctatta cgcatccgtt ttggaaagtg gggtcccatc aaggttcagt ggcagtggat
      301 ctgggacaga attcactctc accatcagca gtctgcagcc tgaggatttt gcaacttatt
      361 actgtcaaca gtataacagt gacccattca ctttcggccc cgggaccaaa ctggatacca
      421 aacgag
//
LOCUS       KCVT01007440             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21260:9758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007440
VERSION     KCVT01007440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21260:9758"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84965.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          109 c          110 g           99 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attgagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cgttaacgtt tatttaaatt ggtatcagca gaaaccgggg aaagccccta agcccctgat
      241 cttttatgca aaccgtttgg aacgtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa gttattattg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007441             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:15066:3898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007441
VERSION     KCVT01007441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15066:3898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84966.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccactg gggacattgt gctgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagaacctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaatc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggagcct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagaat ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01007442             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22054:3018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007442
VERSION     KCVT01007442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22054:3018"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84967.1"
                     /translation="CQQHDNSPWTF"
     J_segment       382..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          110 a          116 c          109 g           87 t
ORIGIN      
        1 acatgggagt cagtctcaga caggacacag catggacacg agggtccccg atcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagag
      181 tattaacgac tggttggcct ggtatcaaca gagaccaggg aaggccccta acctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcagcagcct gcagcctgaa gatatcgcaa catattactg
      361 tcaacagcat gataattccc cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01007443             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12273:17935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007443
VERSION     KCVT01007443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12273:17935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..415
                     /note="immunoglobulin light chain variable region"
     V_region        101..415
     V_segment       101..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84968.1"
                     /translation="CQQYNNDPPTF"
     J_segment       388..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>425
                     /gene="IGKC"
BASE COUNT          102 a          123 c          110 g           90 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtcg
      181 gggcattagc agtcatttag cgtggtatca gcagagacca gggaaagccc cgaggccctt
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagac ttcactctca ccatcagcag cctgcagcct gaagattttg caacgtatta
      361 ctgtcaacag tataacaatg accctcccac tttcggcccc gggaccaaac tggatgtcag
      421 acgag
//
LOCUS       KCVT01007444             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22294:5948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007444
VERSION     KCVT01007444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22294:5948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..438
                     /note="immunoglobulin light chain variable region"
     V_region        100..438
     V_segment       100..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84969.1"
                     /translation="CMQGLEYPYSF"
     J_segment       401..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          102 a          116 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctggat ccagtgggaa tattgtgatg acccagactc
      121 cactctccct gccagtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgcggat ggaaaaacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccggac ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaggtt tagagtatcc gtacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007445             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23162:2661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007445
VERSION     KCVT01007445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23162:2661"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..356
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84970.1"
                     /translation="SMHDYGWPTTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          115 c          115 g           92 t
ORIGIN      
        1 acatgggggg ctctgagcac cgcctgccag catgttcttg ggagttcagg tgcagctcct
       61 ctggagcctg gctttctgga gggcagtgag tggagacatc atcctgaacc agacgccagc
      121 atccctgact gcacctccag gagagacagt gtccatctcc tgccaagcca gaccagatgt
      181 acatggtgaa ataccttgga tccggataaa ccttgaacaa agacttgaac cccttttatc
      241 tcatgtcact accttggccc caggtgtcgc agcccggttc atcaccaagg ggagtggcac
      301 cagttatgtt ttcagcatca gtgacctgca gcctggggac tctggggact attactccat
      361 gcatgactat gggtggccaa ccactttcgg tggagggacc aaggtggaga tcaaacgaa
//
LOCUS       KCVT01007446             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4314:11578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007446
VERSION     KCVT01007446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4314:11578"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84971.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..440
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          107 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccactggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gaacctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaatcgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagaattt cctctcactt tcggtggagg
      421 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007447             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11290:6815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007447
VERSION     KCVT01007447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11290:6815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84972.1"
                     /translation="CQQYDSDSLTF"
     J_segment       380..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg actcaggaca
      181 ttcgcagtta tttagcgtgg tatcaacaga aaccagggaa agccccgagg cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacaatatga cagtgattcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007448             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:7555:15612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007448
VERSION     KCVT01007448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7555:15612"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..352
                     /note="immunoglobulin light chain variable region"
     V_region        13..352
     V_segment       13..314
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <292..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84973.1"
                     /translation="CMQALEFPLTF"
     J_segment       315..352
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>355
                     /gene="IGKC"
BASE COUNT           80 a           90 c          103 g           82 t
ORIGIN      
        1 acatggggtg gggacattgt gatgacccag actccactct ccctgcccgt cacccttgga
       61 gagccggcct ccatctcctg caggtctagt cagagcctct tggatagtga ggatggaaac
      121 acctatttgg actggtacct gcagaagcca ggccagtctc cacagctctt gatttatgag
      181 gtttccaacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc agacactgat
      241 ttcacactga aaatcagcag agtggaggct gaggatgtcg gggtttatta ctgcatgcaa
      301 gctctagagt ttccgctcac tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01007449             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19353:4999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007449
VERSION     KCVT01007449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19353:4999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..349
                     /note="immunoglobulin light chain variable region"
     V_region        28..349
     V_segment       28..311
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84974.1"
                     /translation="CQKYSSFPFTF"
     J_segment       312..349
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           83 a          101 c           92 g           76 t
ORIGIN      
        1 acatgggggc tcccaggtaa caccggacaa gttatattga ctcagtctcc agccactctg
       61 tctttgtctc caggggaaag agccaccctc tcctgcaggg ccagtcagag tgttggcagc
      121 agcttagcct ggtaccagca gaaacctggg caggccccca gactcctcat ctatggtgca
      181 tccagcaggg ccactggaac cccagacagg ttcagtggca gtgggtctgg gacagagttc
      241 actctcacca tcagcagcct ggagcctgaa gattttgcag tgtattactg tcagaagtat
      301 agtagtttcc cattcacttt cggccccggg accaaactgg atatcaaacg ag
//
LOCUS       KCVT01007450             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10301:7368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007450
VERSION     KCVT01007450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10301:7368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84975.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccaatctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007451             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:12750:7048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007451
VERSION     KCVT01007451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12750:7048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84976.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          114 c          113 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcagc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007452             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:18447:12278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007452
VERSION     KCVT01007452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18447:12278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..384
                     /note="immunoglobulin light chain variable region"
     V_region        63..384
     V_segment       63..346
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84977.1"
                     /translation="CQQHDNSPWTF"
     J_segment       347..384
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>387
                     /gene="IGKC"
BASE COUNT           97 a          107 c          100 g           83 t
ORIGIN      
        1 acatgggggt ccccgctcag ctcctggggc tcctgttgct ctggctccca ggtgccagat
       61 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      121 ccatcacttg cagagccagt cagagtatta acgactggtt ggcctggtat caacagagac
      181 cagggaaggc ccctaagctc ctgatctata gggcatccaa tttggaaaca ggggtcccat
      241 caaggttcag tggaagtgga tctgggacag atttcactct caccatcagc agcctgcagc
      301 ctgaagatat cgcaacatat tactgtcaac agcatgataa ttccccgtgg acgttcggcc
      361 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01007453             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:10792:8182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007453
VERSION     KCVT01007453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10792:8182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..444
                     /note="immunoglobulin light chain variable region"
     V_region        105..444
     V_segment       105..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84978.1"
                     /translation="CMQALEFPWTF"
     J_segment       407..444
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          100 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggct gactgatcac gactcctcag gtcaccttct cacaatgagg ctccctgctc
       61 agctcctggg actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc
      121 agactccagt ctccctgccc gtcaccctta gagagccggc ctccatctcc tgcaggtcta
      181 gtcagagcct cttggatagt gaggatggaa atacctattt ggaatggtac ctacagaggc
      241 caggccagtc tccacagctc ttaatttatg aggtttccta ccgggcctct ggagtcccag
      301 acaggttcag tgggagtggg tcagacactg acttcacact gaaaatcagc agagtggagg
      361 ctgaggatgt tggggtttat tactgcatgc aagctctaga gtttccgtgg acgttcggcc
      421 aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01007454             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14661:3554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007454
VERSION     KCVT01007454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14661:3554"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84979.1"
                     /translation="CQKYSNSPPVFSF"
     J_segment       396..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>433
                     /gene="IGKC"
BASE COUNT          101 a          123 c          117 g           92 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat attgactcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc ccccagggtc
      241 ctcatctata gtgtatccaa cagggccact ggcatcccag acaggttcag tggcggtggg
      301 tctgggacag agttcaccct caccatcagc agcctggagc ctgaagattt tgcagtgtat
      361 tactgtcaga agtatagtaa ctccccaccg gtgttcagtt ttggccaggg gaccaaagtg
      421 gagatcagac gag
//
LOCUS       KCVT01007455             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24533:9156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007455
VERSION     KCVT01007455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24533:9156"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84980.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          118 c          124 g          101 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcag ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgagttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007456             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:4463:13538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007456
VERSION     KCVT01007456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:4463:13538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84981.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcaatggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007457             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:27352:18716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007457
VERSION     KCVT01007457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:27352:18716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84982.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gttggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007458             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5278:11932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007458
VERSION     KCVT01007458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5278:11932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84983.1"
                     /translation="CQQYDSDLFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          108 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatttgttg gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa ctggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acaatatgac agtgacctgt tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007459             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:11555:6412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007459
VERSION     KCVT01007459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11555:6412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84984.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggcaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca attcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01007460             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:14012:3136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007460
VERSION     KCVT01007460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14012:3136"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84985.1"
                     /translation="CQQHNTYPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          107 a          118 c          105 g           91 t
ORIGIN      
        1 acatgggggg agaaccactc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaca gtcaccatca cttgtcgggc aagtcaggac
      181 attagtaatg atttagcctg gtatcagcag aaaccaggga aagccccaaa gcccccgatc
      241 ttttacgcat ccaatttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagcata atacttaccc gtacactttt ggccagggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007461             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20348:17270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007461
VERSION     KCVT01007461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20348:17270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84986.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgccctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01007462             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20670:18098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007462
VERSION     KCVT01007462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20670:18098"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84987.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactttc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007463             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18740:13456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007463
VERSION     KCVT01007463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18740:13456"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84988.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          116 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007464             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17896:17989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007464
VERSION     KCVT01007464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17896:17989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84989.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccaatgggga cattgtgatg acccagactc
      121 cgctctccct gcccgtcatc cttggagagc cggcctccct atcctgcacg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007465             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17331:8584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007465
VERSION     KCVT01007465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17331:8584"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84990.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          117 c          108 g           90 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007466             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:28025:6721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007466
VERSION     KCVT01007466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:28025:6721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84991.1"
                     /translation="CLQYKSYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          113 c          101 g          102 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacgtc cagatgactc agtctccatc
      121 ttccctgtct gcatctgcag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagtacctat ttaaattggt ttcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatct agtctggaaa gtggggtccc atcaaggttc agcggcagtg gatttgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtct
      361 acagtataaa agttatccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007467             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:8702:13747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007467
VERSION     KCVT01007467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8702:13747"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84992.1"
                     /translation="CQQYDKSPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          118 c          116 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acatcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagggtcac catcacttgc agagccagtc
      181 agggtatcag caactggttg gcctggtatc aacagaaacc agggagagcc cctaacctcc
      241 tgatgtatag ggcgtccaat ttgcaaggag gggtcccatc aaggttcaga ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaggatgtc gctacatatt
      361 actgtcaaca gtatgataag tcccctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007468             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13454:11321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007468
VERSION     KCVT01007468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13454:11321"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84993.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007469             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10477:15934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007469
VERSION     KCVT01007469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10477:15934"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84994.1"
                     /translation="CLQGDTAPLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          115 c          117 g           93 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtgggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattatttaa gttggtatca gcagagacca ggaaaaactc ctaggcgcct
      241 gatctatgct gcatccagtt tgggaagtgg ggtcccgtca agattcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag ggtgatactg ccccgctcac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007470             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10128:16579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007470
VERSION     KCVT01007470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10128:16579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84995.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctaatcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctctaca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaggctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007471             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12350:10279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007471
VERSION     KCVT01007471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12350:10279"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84996.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          123 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007472             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:15268:9113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007472
VERSION     KCVT01007472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15268:9113"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84997.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          114 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt taccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgactcgc tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01007473             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:14030:15971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007473
VERSION     KCVT01007473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14030:15971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84998.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          122 c          114 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tatcaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007474             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16872:14260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007474
VERSION     KCVT01007474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16872:14260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV84999.1"
                     /translation="CLQFKTFPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT           99 a          119 c          108 g          102 t
ORIGIN      
        1 acatgggggc aggagtcaga cacagtcagg acacagcatg gacatgaggg cccccgctca
       61 tctcctaggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca
      121 gtctccatct tccctgtctg catctgtagg agacactgtc accatctctt gccgggcaag
      181 tcagggtatt agcagttctt taagttggtt tcagcagaaa ccagggaaag cccctaagct
      241 cctcatctat gctgcatcca ctttggccgg tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gacttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcta cagtttaaaa ctttcccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01007475             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:16392:12557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007475
VERSION     KCVT01007475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16392:12557"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..377
                     /note="immunoglobulin light chain variable region"
     V_region        106..377
     V_segment       106..342
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <319..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85000.1"
                     /translation="CQQHNSYPRTF"
     J_segment       344..377
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>382
                     /gene="IGKC"
BASE COUNT           96 a          106 c          100 g           80 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtaccag atgtgacatc cagatgaccc agtctccatc
      121 acttgccaag ccagtcaggg tattggcaac tggttagcct ggtatcggca gaaaccaggg
      181 aaagccccta agctcctgat ctatgctgca tccagtttac aaagtggggt cccatcaagg
      241 ttcagcggca gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa
      301 gattttgcaa cttattactg tcagcagcat aatagttatc ctcggacgtt cggccaaggg
      361 accaaggtgg aaatcaagcg ag
//
LOCUS       KCVT01007476             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:18020:13899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007476
VERSION     KCVT01007476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18020:13899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85001.1"
                     /translation="CQQDSHWPTF"
     J_segment       387..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           96 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctac agggccagtc
      181 agagtgtcag cagccggtta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatgtttgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcagca gcctggagcc tgaagatgtt gcgctttatt
      361 tttgtcagca ggatagtcac tggcctacgt tcggccaagg gaccaaggtg gaactcaaac
      421 gag
//
LOCUS       KCVT01007477             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5749:15641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007477
VERSION     KCVT01007477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5749:15641"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..243
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <220..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85002.1"
                     /translation="CMQALEFPWTF"
     J_segment       244..280
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>283
                     /gene="IGKC"
BASE COUNT           70 a           60 c           85 g           68 t
ORIGIN      
        1 acatggggca ggtctagtca gagcctcttg gatagtgagg atggaaacac ctatttggaa
       61 tggtacctgc agaagccagg ccagtctcca cagctcttga tttttgaggt ttcctaccgg
      121 gcctctggag tcccagacag gttcagtggc agtgggtcag acactgattt cacactgaaa
      181 atcagcagag tggaggctga ggatgttggg atttattact gcatgcaagc tctagagttt
      241 ccttggacgt tcggccaagg gaccagggtg gaaatcaaac gag
//
LOCUS       KCVT01007478             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7328:12080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007478
VERSION     KCVT01007478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7328:12080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85003.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          121 c          122 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggcc ccctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007479             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14993:12305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007479
VERSION     KCVT01007479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14993:12305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85004.1"
                     /translation="CLQYKSFPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          109 c          105 g          103 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgtg ggagacactg tcaccatcac ttgccggaca agtcaggata
      181 ttaacagtta tttaaattgg tttcagcaga taccagggaa aggcccaaag gtcctgatcc
      241 atgctgcatc cagtttggaa agtggggtcc cgtctaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcaacctgc agcctgcaga ttttgcaact tattattgtc
      361 tacagtataa aagttttcct ctcactttcg gtggagggac caaggtggat atcaaacgag
//
LOCUS       KCVT01007480             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:9148:7370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007480
VERSION     KCVT01007480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9148:7370"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85005.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacagt gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007481             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:7237:6968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007481
VERSION     KCVT01007481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7237:6968"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85006.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatgtca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007482             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:24962:7840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007482
VERSION     KCVT01007482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24962:7840"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85007.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007483             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15777:15678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007483
VERSION     KCVT01007483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15777:15678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    71..392
                     /note="immunoglobulin light chain variable region"
     V_region        71..392
     V_segment       71..350
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85008.1"
                     /translation="CQQYDSDSLTF"
     J_segment       355..392
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>395
                     /gene="IGKC"
BASE COUNT           95 a          108 c          100 g           92 t
ORIGIN      
        1 acatggggac atgagggtcc ccgctcagct cctaggactc ctgctgctct gtctcccagg
       61 tgccaaatgt gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga
      121 cagagtcacc atcacttgtc gggcgactca ggacattcgc agttatttag cgtggtatca
      181 gcagaaacca gggaaagccc cgaagccctt gatctattac gcgtccactt tggaaagtgg
      241 ggtcccatca aggttcagcg gcagtggatc tgggacagat ttcactctca ccatcaacag
      301 cctgcagcct gaagattttg caacttatta ctgtcaacag tatgacagtg attcgctcac
      361 tttcggtgga gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01007484             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:18697:12473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007484
VERSION     KCVT01007484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18697:12473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85009.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccatacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007485             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:8964:8861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007485
VERSION     KCVT01007485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8964:8861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85010.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggtc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007486             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:14027:13594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007486
VERSION     KCVT01007486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14027:13594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85011.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          111 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 taggagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacacatcc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc agagtggaga tccaacgag
//
LOCUS       KCVT01007487             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14072:3074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007487
VERSION     KCVT01007487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14072:3074"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85012.1"
                     /translation="CQQDYSWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          121 c          117 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctc
       61 gtcttcctcc tgctactctg gatcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca gcatcttagc ctggtaccac cagaaacctg ggcaggctcc caagtccctc
      241 atctatggtg caaccagtag ggccaccggc atcccagaca ggttcagtgg cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg cgtttattac
      361 tgtcagcagg attatagctg gccactcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007488             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9454:9349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007488
VERSION     KCVT01007488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9454:9349"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85013.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acagggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007489             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:28365:14433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007489
VERSION     KCVT01007489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:28365:14433"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85014.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          123 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgagt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007490             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:24633:12188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007490
VERSION     KCVT01007490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24633:12188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85015.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 ccagtggcag tgggtcagac actgatttca cacttaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007491             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11579:9532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007491
VERSION     KCVT01007491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11579:9532"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85016.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          125 c          117 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggcccgggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01007492             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5546:16748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007492
VERSION     KCVT01007492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5546:16748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85017.1"
                     /translation="CMQALEFPFTF"
     J_segment       405..442
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          125 c          117 g          107 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga taatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa gctctagagt ttccattcac cttcggcccc
      421 gggaccaatc tggatatcaa acgag
//
LOCUS       KCVT01007493             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:8626:14969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007493
VERSION     KCVT01007493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8626:14969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85018.1"
                     /translation="CQQYDSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaaggcctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttactg
      361 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01007494             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8664:17023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007494
VERSION     KCVT01007494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8664:17023"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85019.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          118 c          124 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agcggggaca ttgtgatgac ccagactcca
      121 ctctccctgt ccgtcaccct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggatg gtgaggatgg aaacacctac ttggaatggt atttccagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc aagcgggcct ctggagtcgc agacaggttc
      301 agtggcagtg ggtcaggcac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt atcactgcat gcaagctcta gagtttcctc tcactttcgg cggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01007495             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15754:8285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007495
VERSION     KCVT01007495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15754:8285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..359
                     /note="immunoglobulin light chain variable region"
     V_region        82..359
     V_segment       82..321
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85020.1"
                     /translation="CQQYDSDPFTF"
     J_segment       324..359
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>362
                     /gene="IGKC"
BASE COUNT           91 a           94 c           99 g           78 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggagacag agtcaccatt acttgtcggg cgagtcaggg
      121 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga aggccttgat
      181 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      301 tcaacagtat gacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      361 ag
//
LOCUS       KCVT01007496             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:24489:4869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007496
VERSION     KCVT01007496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24489:4869"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85021.1"
                     /translation="CQQYNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          119 c          109 g           90 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacc aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag tataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007497             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20494:4589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007497
VERSION     KCVT01007497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20494:4589"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85022.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          124 c          111 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct cctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc aaaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag attcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007498             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13451:13080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007498
VERSION     KCVT01007498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13451:13080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85023.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctcccc gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007499             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:18866:17837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007499
VERSION     KCVT01007499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18866:17837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85024.1"
                     /translation="CQQYDSDSLTF"
     J_segment       381..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           94 t
ORIGIN      
        1 atggggagtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gactcaggac
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007500             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:19810:14244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007500
VERSION     KCVT01007500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19810:14244"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85025.1"
                     /translation="CLQYYSIPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          104 g          101 t
ORIGIN      
        1 acatggggga agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat ctgcaggaga cagagtcacc atcacttgca gggcaggtca
      181 gggcattagt actcatttaa attggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatctatgct gcgtccagtt tggagagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttattt
      361 ctgtctacag tattatagta tcccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01007501             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20971:9043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007501
VERSION     KCVT01007501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20971:9043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85026.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01007502             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:12376:20409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007502
VERSION     KCVT01007502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12376:20409"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85027.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c          103 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcaggacat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccaaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007503             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22329:18545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007503
VERSION     KCVT01007503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22329:18545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85028.1"
                     /translation="CQQGYNYPWTF"
     J_segment       379..412
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT           99 a          116 c          108 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgtgg gagacacagt cacgatctct tgccaggcga gtcaaggcat
      181 tgacaataat ttaaattggt ttcagcagac accagggaaa gcccctaaac tcctgatcta
      241 taagacatcc agtttgcaga gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctggagat tttgccactt attactgtca
      361 acagggttat aattacccgt ggacgttcgg ccaagggacc aaggtggaaa tccaacgag
//
LOCUS       KCVT01007504             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18603:5716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007504
VERSION     KCVT01007504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18603:5716"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..376
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85029.1"
                     /translation="CQQYNTLITF"
     J_segment       378..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT          108 a          110 c          104 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcgct tgccgggcaa gtcaggacat
      181 aagtaattat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttacacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt atttctgtca
      361 acagtataac actttaatca ctttcggcgg gggaaccaag gtggagatca aacgag
//
LOCUS       KCVT01007505             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:19115:15873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007505
VERSION     KCVT01007505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19115:15873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85030.1"
                     /translation="CQQHDNSPWTF"
     J_segment       380..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          109 a          115 c          110 g           86 t
ORIGIN      
        1 acatggggga gtctcagaca ggacacagca tggacacgag ggtccccgct cagctcctgg
       61 ggctcctgtt gctctgactc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagagta
      181 ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag ctcctgatct
      241 atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca tattactgtc
      361 aacagcatga taattccccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01007506             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18121:20564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007506
VERSION     KCVT01007506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18121:20564"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85031.1"
                     /translation="CMQGKEFPYSF"
     J_segment       400..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          115 c          124 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aagctccctg ctcagctcct
       61 ggggctgcta atgctctggc tccctggatc tagtggggat gttgtgatga cccagactcc
      121 actctccctg ccagtcaccc ctggagagtc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga ggccaggcca
      241 gtctccacag cccttgattt atggggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaggcaa agagtttccg tacagttttg gccaggggac
      421 caaagtggag atcaaacgag
//
LOCUS       KCVT01007507             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:16537:14416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007507
VERSION     KCVT01007507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16537:14416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85032.1"
                     /translation="CQQHNGYPPTF"
     J_segment       367..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           99 a          113 c          105 g           87 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattacca atgatttagc
      181 ctggtatcag cagagaccag ggaaagcccc gaagcccctg atctattacg catcgaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattat tgtcaacagc ataatggata
      361 ccctccgacg ttcggccaag ggaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01007508             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:25592:10842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007508
VERSION     KCVT01007508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25592:10842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85033.1"
                     /translation="CQQYNSEPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          112 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gggggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaacccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgag ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007509             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4467:14731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007509
VERSION     KCVT01007509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4467:14731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85034.1"
                     /translation="CQQHNGYPPTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          119 c          105 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca acatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattacgaa tgatttagcc tggtatcaac agaaaccagg taaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtcaacagca taatggatac cctccgacgt tcggccaagg gaccagggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007510             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15620:4974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007510
VERSION     KCVT01007510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15620:4974"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85035.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007511             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13487:12906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007511
VERSION     KCVT01007511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13487:12906"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85036.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          122 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct acccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggcgat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagggtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007512             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:17122:9738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007512
VERSION     KCVT01007512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17122:9738"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85037.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          123 c          123 g           97 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg ctagagagga tggaaacacc tatttggact ggtacctgca gaggccaggc
      241 cagactcccc agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 gtcagaggca gtgggtcaga cactgagttc acactgaaaa tcagcagagt ggaggctgaa
      361 gatcttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007513             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21652:8277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007513
VERSION     KCVT01007513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21652:8277"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85038.1"
                     /translation="CQQYDSDLFTF"
     J_segment       387..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          114 c          113 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ttgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acctgttcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007514             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:24489:6487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007514
VERSION     KCVT01007514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24489:6487"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85039.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gttgggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007515             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:17826:16754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007515
VERSION     KCVT01007515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17826:16754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85040.1"
                     /translation="CQQNSNWPLTF"
     J_segment       384..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          123 c          114 g           85 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcgtagcc tggtaccagc agaaacctgg gcaggctccc agactcctca
      241 tctatggtgc atccaacagg gccactggca tcccagacag gttcagtggc agtgggtctg
      301 ggacagagtt cactctcacc atcagcagcc tggagcctga agatgttgca ctttattatt
      361 gtcagcagaa tagtaactgg cctctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007516             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20072:13805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007516
VERSION     KCVT01007516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20072:13805"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85041.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          115 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agagccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007517             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10162:16233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007517
VERSION     KCVT01007517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10162:16233"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85042.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcactggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007518             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:10462:8719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007518
VERSION     KCVT01007518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10462:8719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85043.1"
                     /translation="CQQYNSFPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          100 a          117 c          111 g          100 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacgtgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc acttgaccca
      121 gtctccatcc tccctgtctg cttctctagg agacagagtc accctctctt gccgggcaag
      181 tcagggcgtt agcagttatt taaattggta tcagcagaaa ccggggaaag cccctaacct
      241 cctgatctat tatgcaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaggatt ttgcaactta
      361 ttactgtcaa cagtataata gttttcctct cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01007519             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14435:12123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007519
VERSION     KCVT01007519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14435:12123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85044.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          115 c          104 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatttct tgccgggcaa gtcagtgtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt attactgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007520             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:14444:15700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007520
VERSION     KCVT01007520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14444:15700"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..439
                     /note="immunoglobulin light chain variable region"
     V_region        122..439
     V_segment       122..397
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85045.1"
                     /translation="CQQGYNYPCTF"
     J_segment       410..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>446
                     /gene="IGKC"
BASE COUNT          105 a          125 c          115 g          101 t
ORIGIN      
        1 acatggggag gctggtcaca ccctgtgcag gagtcagtct cagtcaggac acagcatgga
       61 catgagggtc cccgctcagc tccttgggct cctgctgctc tggctcccag gtgccagatg
      121 tgacatccag atgacgcagt ctccatccac cctgtccgca tctgtgggag acacagtcac
      181 gatctcttgc caggcgagtc aaggcattga caataattta aattggtttc agcagacacc
      241 agggaaagcc cctaaactcc tgatctataa gacatccagt ttgcagagtg ggattccctc
      301 tcgcttcagc ggcagtgggt ctgggacgga tttcactctc accatcagca gcctgcagcc
      361 tgaagatttt gccacttatt actgtcaaca gggttataat tacccgtgta cgttcggcca
      421 agggaccaag gtggaaatcc aacgag
//
LOCUS       KCVT01007521             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11950:7872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007521
VERSION     KCVT01007521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11950:7872"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85046.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatactgag gatggaaata cctatttgga atggcaccgg cagatgccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctgacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007522             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10039:8280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007522
VERSION     KCVT01007522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10039:8280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85047.1"
                     /translation="CLQGYIIPYNF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          110 c          112 g          100 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattagc gattttttaa gttggtatca gcagaaacca ggaaaacctc ctaagcgcct
      241 gatttatgct gcatccagtt tggaaagtgg ggtcccgtca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cggcttatta
      361 ttgtctacag ggttatatta tcccgtacaa ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007523             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:13537:15257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007523
VERSION     KCVT01007523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13537:15257"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..318
                     /note="immunoglobulin light chain variable region"
     V_region        8..318
     V_segment       8..276
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85048.1"
                     /translation="CQQYDSDSLTF"
     J_segment       281..318
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>321
                     /gene="IGKC"
BASE COUNT           81 a           83 c           83 g           74 t
ORIGIN      
        1 acatggggac ccagtctcca tcctccctgt ctgcatctgt aggagacaga gtcaccatca
       61 cttgtcgggc gactcaggac attcgcagtt atttagcgtg gtatcagcag aaaccaggga
      121 aagccccgaa gcccttgatc tattacgcgt ccactttgga aagtggggtc ccatcaaggt
      181 tcagcggcag tggatctggg acagaattca ctctcaccat cagcagcctg cagcctgaag
      241 attttgcaac ttattactgt caacagtatg acagtgattc gctcactttc ggtggaggga
      301 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007524             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:19891:4495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007524
VERSION     KCVT01007524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19891:4495"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85049.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgggt ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gccccttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007525             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:24414:8636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007525
VERSION     KCVT01007525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24414:8636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85050.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           96 a          127 c          115 g           87 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtcc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc cccgactcct
      241 catctatggt gcatccaaca gggccactgg cttcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttattt
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007526             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20157:14048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007526
VERSION     KCVT01007526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20157:14048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..394
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85051.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttggc tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaagttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagtagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagacttccc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007527             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21666:9751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007527
VERSION     KCVT01007527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21666:9751"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85052.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc ccaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007528             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16825:12837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007528
VERSION     KCVT01007528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16825:12837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85053.1"
                     /translation="CQQYHSFPLTF"
     J_segment       384..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          103 a          111 c          108 g          101 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccagggg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggggaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtag ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tgtattattc aaaccgtttg gaaagtgggg tcccatcaaa gttcagcggc ggtggatctg
      301 ggacagaatt cactctcacc atcatcaacc tgcaacctga agatttttca acttattact
      361 gtcaacagta tcatagtttt cctctcactt tcggcggagg gaccaaggtg gagatcagac
      421 gag
//
LOCUS       KCVT01007529             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17095:15885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007529
VERSION     KCVT01007529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17095:15885"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85054.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          120 c          123 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccaggct
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atggtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007530             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21654:17416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007530
VERSION     KCVT01007530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21654:17416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85055.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcccgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007531             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19513:10786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007531
VERSION     KCVT01007531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19513:10786"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..417
                     /note="immunoglobulin light chain variable region"
     V_region        104..417
     V_segment       104..387
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85056.1"
                     /translation="CLQGDSTPFTF"
     J_segment       394..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>428
                     /gene="IGKC"
BASE COUNT          103 a          115 c          114 g           96 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatct tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt agcgattatt taagttggta tcagcagaaa ccgggaaaag ctcctaagcg
      241 cctaatctat gctgcatcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gagttcactc tcaccatcag cagcctgcag cctgaagatt ttgcgactta
      361 ttactgtcta cagggtgata gtaccccgtt cacttttggc caggggacca aagtggacgt
      421 caaacgag
//
LOCUS       KCVT01007532             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11125:14447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007532
VERSION     KCVT01007532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11125:14447"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85057.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgcat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaagat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgactttt ccaaccgggc ctctggagtc ccggacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007533             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:22751:12842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007533
VERSION     KCVT01007533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22751:12842"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85058.1"
                     /translation="CQQHDNSPPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccttc
      121 ctccctgtct gcatctattg gcgacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcgactgg ttggcctggt atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca ggctgaagat ttcgcaacat atttctgtca
      361 acagcatgat aattcccctc ccactttcgg tggagggact aaggtggaga tcaaacgag
//
LOCUS       KCVT01007534             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19027:3304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007534
VERSION     KCVT01007534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19027:3304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..394
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85059.1"
                     /translation="CLQSKNSPWTF"
     J_segment       395..432
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>435
                     /gene="IGKC"
BASE COUNT          104 a          115 c          116 g          100 t
ORIGIN      
        1 acatggggga ggagcagcct ctagttcagc tctcagaaat ggggtcctgg gctcctttcc
       61 tgtggatcct cctgctctgt gctccaggct gcaatgggga cattgtgctg acccagtctc
      121 cagcctcttt ggccgtgtct ccagggcaga gggccaccat cgtctgcaga gccagtgaga
      181 gtgtcaatgt ctttggaata aacctcattc actggtatca gcagaaacca ggacaacctc
      241 ctaaacccct gatttaccaa gcatccaata aagaaactgg ggtcccagcc aggttcagcg
      301 gcagtgggtc tgggaccgat ttcaccctca caattaatcc tgtggaagct gacgatgctg
      361 cagattatta ctgtctgcag agtaagaatt ctccgtggac gtttggccaa gggaccaagg
      421 tggaaatcaa acgag
//
LOCUS       KCVT01007535             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17877:17019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007535
VERSION     KCVT01007535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17877:17019"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..395
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85060.1"
                     /translation="CLQSKNSPWSF"
     J_segment       396..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          100 t
ORIGIN      
        1 acatgggggg aggagcagcc tctagttcag ctctcagaaa tggggtcctg ggctcctttc
       61 ctgtggatcc tcctgctctg tgctccaggc tgcactgggg acattgtgct gacccagtct
      121 ccagcctctt tggccgtgtc tccagggcag agggccacct tcacctgcag agccagtggg
      181 agtgtcagtg cctttggaat aagcctcatt cactggtatc agcagaaacc aggacaacct
      241 cctaaactcc tgatttatca agcaagcaat aaggagactg gggtcccagc caggttcagc
      301 ggcagtgggt ctgggaccga tttcaccctc acaattaatc ctgtggaacc tgacgatgct
      361 gcagattatt actgtctgca gagtaagaat tctccgtggt cgttcggcca agggaccaag
      421 gtggaaatca aacgag
//
LOCUS       KCVT01007536             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:22638:6634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007536
VERSION     KCVT01007536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22638:6634"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85061.1"
                     /translation="CQQHNTYPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          118 c          105 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gacattagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc aaagcccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatactta cccgtacact tttggccagg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007537             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:5864:10329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007537
VERSION     KCVT01007537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5864:10329"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85062.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           93 a          118 c          127 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc gcccttggag agccggcctc catctcctgt gggtctagtc
      181 agagcctctt ggatggtgag gatggaaaca cctatttgga atggtacctg cagaggccag
      241 gccagtctcc acagctgttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttatttc tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaattcaaa cgag
//
LOCUS       KCVT01007538             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:8371:9265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007538
VERSION     KCVT01007538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8371:9265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85063.1"
                     /translation="CQQVYSNPAF"
     J_segment       387..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          111 c          110 g           99 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggtcc ctgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gatatccagg tgacccagtc
      121 tccatctgcc ttgtctgcat ctgtaggaga cagagtcacc atctcttgcc gggcaagtca
      181 gaacatttat aggaatttag cgtggtatca gcagaaacca gggaaagccc ctaagctcct
      241 gatctttgct gcatccagat tgcaaagtgg gattccctct cggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcaa cctacagcct gaagattctg caatttatta
      361 ctgtcaacag gtttatagta acccggcgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01007539             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:24030:15857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007539
VERSION     KCVT01007539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24030:15857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    46..385
                     /note="immunoglobulin light chain variable region"
     V_region        46..385
     V_segment       46..348
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <325..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85064.1"
                     /translation="CMQALEFPWTF"
     J_segment       349..385
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>388
                     /gene="IGKC"
BASE COUNT           87 a           98 c          112 g           91 t
ORIGIN      
        1 acatgggtgg gactgctaat gctctggctc cctggatcca gtggggacat tgtgatgacc
       61 cagactccag tctccctgcc cgtcaccctg ggagagccgg cctccatctc ctgcaggtct
      121 agtcagagcc tcttggatag tgaggatgga aacacctatt tggaatggca cctgcagagg
      181 ccaggccagt ctccacagct cttgatttat gaggtttcct atcgggcctc tggagtccca
      241 gacaggttca gtggcagtgg gtcagacact gatttcacac tgaaaatcag cagagtggag
      301 gctgaggacg ttggtattta ttactgcatg caagctctag agtttccttg gacgttcggc
      361 caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01007540             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:27738:12128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007540
VERSION     KCVT01007540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:27738:12128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85065.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cactgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcggac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007541             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11296:13134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007541
VERSION     KCVT01007541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11296:13134"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85066.1"
                     /translation="CQQYDSFPFTF"
     J_segment       386..423
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          116 c          102 g           99 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacattcag atgacccagt
      121 ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc cgggcaagtc
      181 aggacattag cagttattta aactggtatc agcagaaacc ggggaaagcc cctaaactcc
      241 tgatctatta tacaaatcgt ttggaaactg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgatagt tttccattca ctttcggccc cgggaccaaa ctggatatca
      421 aacgag
//
LOCUS       KCVT01007542             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:15938:14569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007542
VERSION     KCVT01007542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15938:14569"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85067.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctactcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cttggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007543             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11992:9566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007543
VERSION     KCVT01007543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11992:9566"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..439
                     /note="immunoglobulin light chain variable region"
     V_region        118..439
     V_segment       118..399
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85068.1"
                     /translation="CLQESNWSYSF"
     J_segment       402..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT          101 a          123 c          129 g           89 t
ORIGIN      
        1 acatgggggg gtcagagctc tggggaggaa ctgctcagtt aggacccaga gggaaccatg
       61 gaagccccag cacagcttct cttcctcctg ctgctctggc tcccagatag taccggagaa
      121 atagtggtga cacagtctcc agccaccctg tctttgtctc caggggaaag agccaccctc
      181 tcctgcaggg ccagtcagag tgtcaaaagc aggttagcct ggtaccagca gaaacctggg
      241 caagctccca ggctcctcat gtatgatgcg tccagcaggg ccactggcat cccagacagg
      301 ttcactggca gcgggtctgg gccagagttc actctcacca tcagcagcct ggagcctgaa
      361 gatgttgcgg tttatttctg tcttcaggag agtaactggt cgtacagctt tggccagggg
      421 accaaagtgg agatcaaacg ag
//
LOCUS       KCVT01007544             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19814:7710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007544
VERSION     KCVT01007544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19814:7710"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85069.1"
                     /translation="CQQYNNDPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          104 a          112 c          111 g           94 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccaggtgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gagtcaggac
      181 attagaagtt atttagcgtg gtatcagatg agaccaggga aagccccgag ggccttaatc
      241 tattacgcga ccattttgga aggtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cggcagcctg cagcctgagg attttgcaac ttatttctgt
      361 caacagtata acaatgaccc gtacactttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007545             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6559:6300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007545
VERSION     KCVT01007545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6559:6300"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85070.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>440
                     /gene="IGKC"
BASE COUNT           91 a          120 c          124 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cggtggggac attgtgatga cccaggctcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagactct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcagacgag
//
LOCUS       KCVT01007546             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:22051:17403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007546
VERSION     KCVT01007546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22051:17403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85071.1"
                     /translation="CMQSLEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacttg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007547             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21484:6818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007547
VERSION     KCVT01007547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21484:6818"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85072.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactct gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01007548             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5217:20541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007548
VERSION     KCVT01007548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5217:20541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..395
                     /note="immunoglobulin light chain variable region"
     V_region        74..395
     V_segment       74..357
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85073.1"
                     /translation="CQQYDSDPFTF"
     J_segment       360..395
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>398
                     /gene="IGKC"
BASE COUNT           96 a          107 c          104 g           91 t
ORIGIN      
        1 acatgggatg gacatgaggg tccccgctca gctcctagga ctcctgctgc tctgtctccc
       61 aggtgccaaa tgtgacatcc agatgaccca gtctccatcc tccctgtctg catctgtagg
      121 agacagagtc accatcactt gtcgggcgag tcagggcatt cgcagttatt tagcgtggta
      181 tcagcagaaa ccagggaaag ccccgaaggc cttgatctat tacgcgtcca ctttggaaag
      241 tggggtccca tcaaggttca gcggcagtgg atctgggaca gaattcactc tcaccatcag
      301 cagcctgcag cctgaagatt ttgcaactta ttactgtcaa cagtatgaca gtgacccgtt
      361 cactttcggt ggagggacca aggtagagat caaacgag
//
LOCUS       KCVT01007549             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:27809:10857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007549
VERSION     KCVT01007549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:27809:10857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..357
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85074.1"
                     /translation="SMHDSGGPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           96 a          114 c          118 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tctccatctc ctgccaagcc agagcagatg
      181 tacatggtga aatgtcttgg atccggataa accttgaaca aagacttgaa ccccttttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagcccggtt catcagcaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgactc tggggggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01007550             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:12164:19440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007550
VERSION     KCVT01007550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12164:19440"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85075.1"
                     /translation="CVQYKSYAFSF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          110 c          104 g          106 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctctt gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtttc
      121 catcttccct gtctgcgtct gtaggagaca ctgtcaccat cacttgccgg gcaagtcagg
      181 ttattatcag ctatttaaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tttatggtgc atccagtttg gcaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca agttattact
      361 gtgttcagta taaaagttac gctttcagtt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01007551             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:10194:14989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007551
VERSION     KCVT01007551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10194:14989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..245
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85076.1"
                     /translation="CQQYNSLPYSF"
     J_segment       246..283
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           81 a           64 c           73 g           68 t
ORIGIN      
        1 acatggggag acagagtcac catcacttgc cgggcaagtc agggcgttaa cgtttattta
       61 aattggtatc agcagaaacc ggggaaagcc cctaagcccc tgatctttta tgcaaaccgt
      121 ttggaacgtg gggtcccatc aaggttcagc ggcagtggat ctgggacaga attcactctc
      181 accatcagca gcctgcaacc tgaagatttt gcaagttatt attgtcaaca gtataatagt
      241 ttaccgtaca gttttggcca ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01007552             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:24981:22657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007552
VERSION     KCVT01007552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24981:22657"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85077.1"
                     /translation="CEQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          113 a          110 c          101 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggta ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacat ttatttaaat tggtatcacc agaaaccggg gaaagcccct aagctcctga
      241 tttattatac aaatcgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtgaacaata caatagttta ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007553             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:24708:14230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007553
VERSION     KCVT01007553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24708:14230"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85078.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacac gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007554             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:11698:18061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007554
VERSION     KCVT01007554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11698:18061"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85079.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          118 c          106 g           89 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttacgaatga tttagcctgg tatcaacaga aaccaggtaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacagcataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01007555             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19649:11893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007555
VERSION     KCVT01007555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19649:11893"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85080.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          116 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactatatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007556             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:3875:13531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007556
VERSION     KCVT01007556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3875:13531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85081.1"
                     /translation="CLQYNSNPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          114 c          105 g           95 t
ORIGIN      
        1 acatgggagt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg caggggacag agtcaccatc acttgcaggg caagtcagga
      181 cattagcact tatttaaatt ggtatcagca taaaccagga aaacctccta agcgcctgat
      241 ctatggtgca tacagtttgg gaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagatttc actctcacca tcagtagcct gcagcctgaa gattttgcaa cttattactg
      361 tctacagtat aatagtaacc ctccgacgtt cggccaaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007557             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21261:19755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007557
VERSION     KCVT01007557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21261:19755"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85082.1"
                     /translation="CQQYNSLPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          109 c          107 g           98 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacac agtcaccatc acttgccggg caagtcagga
      181 cattagcaga tatttaaatt ggtatcagca gaaaccgggg aaagccccta agttcctgat
      241 ctattatgta aaccgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattattg
      361 tcaacagtat aatagtttac cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007558             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15142:13468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007558
VERSION     KCVT01007558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15142:13468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85083.1"
                     /translation="CQQHDNSPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          112 g           87 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 agtattaacg actggttggc ctggtatcaa cagagaccag ggaaggcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcaacagc atgataattc cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007559             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:16241:8780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007559
VERSION     KCVT01007559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16241:8780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85084.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcaactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007560             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:25838:11363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007560
VERSION     KCVT01007560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25838:11363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85085.1"
                     /translation="CQQNSNWPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          125 c          112 g           86 t
ORIGIN      
        1 acatggggga ctgctcagtt aggacccaga gggaaccatg gaagccccag cacagcttct
       61 cttcctcctg ctgctctggc tcccagatac caccggagaa atagtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggagaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgtcagcagc agcttagcct ggtaccaaca aaaacctggg caggctccca ggctcctcat
      241 ctatggtgca tccagcaggg ccactggcat cccagacagg ttcagtggca gtgggtctgg
      301 gacagacttc actctcacca tcaccagcct ggagcctgaa gatgttgcag tctatttttg
      361 tcagcagaat agtaactggc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007561             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:9648:22174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007561
VERSION     KCVT01007561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9648:22174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85086.1"
                     /translation="CQQYDSDSLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          117 c          112 g           94 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      181 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01007562             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:15539:11514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007562
VERSION     KCVT01007562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15539:11514"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..370
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <353..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85087.1"
                     /translation="CQQGYSYPYSF"
     J_segment       376..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT           97 a          117 c          107 g           95 t
ORIGIN      
        1 atgggggtct cagtcaggac acagcatgga catgagggtc cccgctcagc tccttgggct
       61 cctgctgctc tggctcccag gtgccagatg tgacatccag atgacgcagt ctccatcctc
      121 cctgtccgca tctgcaggag acacagtcac catcacttgc caggcgagtc aaggcattgg
      181 caatacttta aattggtatc aacagaaacc ggggaaagcc cctacactcc tgatctatag
      241 ggcatccggt ttgcaaagtg ggactccctc tcggttcagc ggcagtggat ctgggacgga
      301 tttcactctc accatcagca gcctgcagcc tgaagatttt gccacttatt actgtcaaca
      361 gggttatagt tatccgtaca gttttggcca ggggaccaaa ctggagatca aacgag
//
LOCUS       KCVT01007563             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:12342:14501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007563
VERSION     KCVT01007563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12342:14501"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85088.1"
                     /translation="CQQVYTNPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          103 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gccagaacat
      181 ttggagttat ttagcgtggt atgagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctacatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaactt attactgtca
      361 acaggtttat actaacccat tcactttcgg ccccgggacc aaactggaaa tcaaacgag
//
LOCUS       KCVT01007564             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:6133:6532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007564
VERSION     KCVT01007564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:6133:6532"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..275
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85089.1"
                     /translation="CQQHNTYPLTF"
     J_segment       280..313
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           85 a           83 c           73 g           75 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt
       61 cgggcaagtc aggacattag taatgattta gcctggtatc agcagaaacc agggacagcc
      121 ccgaagcccc tgatgtatta cgcatccaat ttggaaagtg gggtcccatc aaggttcagt
      181 ggcagtggat ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt
      241 gcaagttatt actgtcaaca gcataatact tacccattga ctttcggccc cgggaccaaa
      301 ctggatatca aacgag
//
LOCUS       KCVT01007565             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21274:7785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007565
VERSION     KCVT01007565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21274:7785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..276
                     /note="immunoglobulin light chain variable region"
     V_region        73..276
     V_segment       73..239
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85090.1"
                     /translation="CQQNSNWPLTF"
     J_segment       240..276
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           64 a           78 c           77 g           60 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagac tcctcatcta tggtgcgtcc aacagggcca
      121 ctggcatccc agacaggttc agtggcagtg ggtctgggac agagttcact ctcaccatca
      181 gcagcctgga gcctgcagat gttgcacttt attattgtca gcagaatagt aactggcctc
      241 tcactttcgg aggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007566             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18276:18789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007566
VERSION     KCVT01007566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18276:18789"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85091.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agtctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggcg gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgat
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007567             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19828:17741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007567
VERSION     KCVT01007567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19828:17741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..354
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85092.1"
                     /translation="CQQHNNYSPTF"
     J_segment       367..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           99 a          115 c          101 g           89 t
ORIGIN      
        1 acatgggcac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccaccctccc tgtctgcatc
      121 tgtaggagac acagtcacca tcacttgtcg ggcaagtcag ggcattagca atgatttagc
      181 ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg atctattacg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagc ataataatta
      361 ctctcccact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007568             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:23903:14030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007568
VERSION     KCVT01007568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23903:14030"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85093.1"
                     /translation="CQQDYDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          119 c          110 g           90 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gatacagtga tgacgcagtc
      121 tccagccacc ttgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcaccttaa tatggtacca ccagaaacct gggcaggctc ccaagctcct
      241 cgtctatggt acatccatca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagact gaagatattg gaatttatta
      361 ttgtcagcag gattatgatt ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007569             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:11153:13207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007569
VERSION     KCVT01007569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11153:13207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85094.1"
                     /translation="CMQDIQFPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           90 a          120 c          119 g          109 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggca ccagtgggga tattgtgatg actcagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcctgca tagtaatggt aacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcagacact gatttcacac tgaaaatcag tcgggtggag gctgaggatg
      361 ttggcgttta ttattgcatg caagatatac agtttccgct cactttcggt ggaggaacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007570             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:5107:16526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007570
VERSION     KCVT01007570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5107:16526"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85095.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01007571             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15026:12028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007571
VERSION     KCVT01007571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15026:12028"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85096.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          117 c          101 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaacccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacaata taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01007572             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11554:11004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007572
VERSION     KCVT01007572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11554:11004"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85097.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacccgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007573             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:15461:7990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007573
VERSION     KCVT01007573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15461:7990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85098.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccattgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007574             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20027:16310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007574
VERSION     KCVT01007574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20027:16310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..381
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85099.1"
                     /translation="CYQHSRGWAF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          122 c          117 g           83 t
ORIGIN      
        1 acatggggga gctgctaggt tagtacccag aaggaaccat ggaagcccca gctcagcttc
       61 tctgccttct gctactctgg ctcccaggta ccaccggaca aattatattg acacagtctc
      121 cagccaccct gtctttggca ccaggggaaa gagccactct ctcctgcagg gccagtgaga
      181 atgttggcag ctacttagcc tggtaccagc agaaccctgg gcaggctccc aggctcctcg
      241 tccacagtgc gtccagcagg gccactgaca tcccagacag gttcagtggc agtgggtctc
      301 ggacagagtt caccctcacc atcagcagtc tggagcctga agatgttgga gtctattact
      361 gctatcaaca tagcaggggg tgggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01007575             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14915:9385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007575
VERSION     KCVT01007575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14915:9385"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85100.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcattctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007576             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17276:24639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007576
VERSION     KCVT01007576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17276:24639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85101.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          117 c          105 g           90 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tacgaatgat ttagcctggt atcaacagaa accaggtaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01007577             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18153:14414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007577
VERSION     KCVT01007577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18153:14414"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85102.1"
                     /translation="CMQALQFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          120 c          118 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga ggccaggcca
      241 gtctccacac ctcttgattt atgagttttc caatcgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac tctgaatatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct acaatttccg tggacgttcg gccaagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007578             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:8648:13406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007578
VERSION     KCVT01007578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8648:13406"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85103.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          108 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atccaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007579             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17942:13638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007579
VERSION     KCVT01007579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17942:13638"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85104.1"
                     /translation="CQQYNSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           91 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtgac ccgcgcactt tcggtgaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007580             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:23349:13777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007580
VERSION     KCVT01007580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23349:13777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85105.1"
                     /translation="CLQESNWSYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           99 a          120 c          120 g           86 t
ORIGIN      
        1 acatggggga gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga tagtaccgga gaaatagtgg tgacacagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcaaa agcaggttag cctggtacca gcagaaacct gggcaagctc ccaggctcct
      241 catgtatgat gcgtccagca gggccactgg catcccagac aggttcactg gcagcgggtc
      301 tgggccagag ttcactctca ccatcagcag cctggagcct gaagatgttg cggtttattt
      361 ctgtcttcag gagagtaact ggtcgtacag ctttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007581             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:14937:14027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007581
VERSION     KCVT01007581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14937:14027"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..331
                     /note="immunoglobulin light chain variable region"
     V_region        8..331
     V_segment       8..293
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85106.1"
                     /translation="CMQALDFPLTF"
     J_segment       295..331
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>334
                     /gene="IGKC"
BASE COUNT           76 a           88 c           93 g           77 t
ORIGIN      
        1 acatgggaga ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc
       61 aggtctagtc agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg
      121 cagaagccag gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga
      181 gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga
      241 gtggaggctg cggatgttgg ggtttattac tgcatgcaag ctctagactt tcccctcact
      301 ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007582             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22115:20262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007582
VERSION     KCVT01007582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22115:20262"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85107.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          121 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggtgagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac tctgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctt tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007583             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:9777:15236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007583
VERSION     KCVT01007583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9777:15236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..281
                     /note="immunoglobulin light chain variable region"
     V_region        5..281
     V_segment       5..239
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85108.1"
                     /translation="CQQYDSDSLTF"
     J_segment       244..281
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>284
                     /gene="IGKC"
BASE COUNT           75 a           69 c           76 g           64 t
ORIGIN      
        1 acatggggac agagtcacca tcacttgtcg ggcgactcag gacattcgca gttatttagc
       61 gtggtatcag cagaaaccag ggaaagcccc gaagcccttg atctattacg cgtccacttt
      121 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      181 catcagcagc ctgcagcctg aagattttgc aacttattac tgtcaacagt atgacagtga
      241 ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007584             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:24284:11687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007584
VERSION     KCVT01007584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24284:11687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85109.1"
                     /translation="CQQHDDSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          116 c          108 g           91 t
ORIGIN      
        1 acatggggga gtcagtctta gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcac agccagtcag
      181 ggtattaata actggttggc ctggtatcaa cagaaaccag gaaaagcccc taaactcctt
      241 atctataggg catccaattt ggaaacaggg gtcccatcga ggttcggtgg aagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatatcgc aacatatttc
      361 tgtcaacagc atgatgattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007585             399 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:17169:10906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007585
VERSION     KCVT01007585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 399)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17169:10906"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..399
                     /note="immunoglobulin light chain variable region"
     V_region        97..399
     V_segment       97..380
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85110.1"
                     /translation="CQKYSSSPFTF"
     J_segment       381..399
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           84 a          120 c          104 g           91 t
ORIGIN      
        1 acatgggggc tgctcagtta ggacccagag agaaccatgg aaatcccagc tcagcttctc
       61 ttcctcctgc tactgtggct cccaggtacc accggacaag ttattttgac tcagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccaccctct cctgcagggc cagtcagagt
      181 gttggcagca gcttagcctg gtaccagcag aaacctgggc aggcccccag actcctcgtc
      241 tatggtgcat ccaggagggc cactggcatc ccagacaggt tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctt gagcctgaag attttgcagt gtattactgt
      361 cagaagtata gtagttcccc attcactttc ggccccggg
//
LOCUS       KCVT01007586             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11928:11157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007586
VERSION     KCVT01007586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11928:11157"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85111.1"
                     /translation="CQQHDNAPWTF"
     J_segment       378..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          106 a          115 c          113 g           84 t
ORIGIN      
        1 acatgggggt ctcagacagg acacagcatg gacacgaggg tccccgctca gctcctgggg
       61 ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gcagagccag tcagagtatt
      181 aacgactggt tggcctggta tcaacagaga ccagggaagg cccctaagct cctgatctat
      241 agggcatcca atttggaaac aggggtccca tcaaggttca gtggaagtgg atctgggaca
      301 gatttcactc tcagcatcag cagcctgcag cctgaagata tcgcaacata ttactgtcag
      361 cagcatgaca atgccccgtg gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01007587             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6232:7992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007587
VERSION     KCVT01007587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6232:7992"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85112.1"
                     /translation="CQQYNSDPRTF"
     J_segment       383..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          116 c          111 g           90 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtataa cagtgacccg cgcactttcg gtgggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007588             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:25649:15266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007588
VERSION     KCVT01007588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25649:15266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85113.1"
                     /translation="CMQSLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg actcagactc
      121 cactctccct ggccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctctaga gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007589             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:19242:8553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007589
VERSION     KCVT01007589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19242:8553"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..405
                     /note="immunoglobulin light chain variable region"
     V_region        99..405
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85114.1"
                     /translation="CQQYNNLPLTF"
     J_segment       386..405
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>422
                     /gene="IGKC"
BASE COUNT          107 a          112 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcgtct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagcaa ttatttaaat tggtatcaac agaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattcct
      361 gtcaacagta taataattta ccgttgacgt tcggccaagg gaccatgggt atttcaaacg
      421 ag
//
LOCUS       KCVT01007590             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9326:22203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007590
VERSION     KCVT01007590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9326:22203"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85115.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          121 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctgaagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007591             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20275:1933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007591
VERSION     KCVT01007591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20275:1933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85116.1"
                     /translation="CQQDFGWPPTF"
     J_segment       400..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          102 a          119 c          124 g           92 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 tccagcacag cttctcttcc tcctgctact ctggatccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ttctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagactgttg gcagcgcctt agcctggtac cagcagaaac ctgggcagac
      241 tcacaagctc ctcatttatg gtgcatccag cagggccacc ggcatcccag acaggttcag
      301 tggcagtggg tctggaacag agttcagtct caccatcagt agtctggagc ctgaggatgt
      361 tggagtttat tactgtcagc aggattttgg ctggcctccg acgttcggcc aagggaccaa
      421 ggtggaaatc aaacgag
//
LOCUS       KCVT01007592             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14418:9665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007592
VERSION     KCVT01007592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14418:9665"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85117.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          126 c          117 g          101 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01007593             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19955:15455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007593
VERSION     KCVT01007593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19955:15455"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85118.1"
                     /translation="CQQDLDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          127 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagcctc cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacagacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gttttctctc accatcagca gcctggagcc tgaagatgtt gcaatttatt
      361 actgtcagca ggatttggac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007594             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:9063:6845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007594
VERSION     KCVT01007594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9063:6845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..379
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85119.1"
                     /translation="CQQHNSYPRTF"
     J_segment       381..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          104 a          116 c          108 g           91 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtaccag atgtgacatc cagatgaccc agtctccatc
      121 ttccttgtct gcatctgtag gagacagagt caccatcact tgccaagcca gtcagggtat
      181 tggcaactgg ttagcctggt atcggcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgcatcc agtttacaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 gcagcataat agttatcctc ggacgttcgg ccaagggacc aaggtggaaa tcaagcgag
//
LOCUS       KCVT01007595             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18198:4170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007595
VERSION     KCVT01007595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18198:4170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85120.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          113 g          110 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ctagtgggga tgttgtgatg acccagactc
      121 cattctccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aagccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggct ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007596             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:13153:10250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007596
VERSION     KCVT01007596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13153:10250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85121.1"
                     /translation="CQQYNSDWRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          111 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac agtgactggc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007597             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20893:5402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007597
VERSION     KCVT01007597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20893:5402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..466
                     /note="immunoglobulin light chain variable region"
     V_region        127..466
     V_segment       127..429
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <406..>438
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85122.1"
                     /translation="CMQALEFPLTF"
     J_segment       430..466
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        467..>469
                     /gene="IGKC"
BASE COUNT          105 a          123 c          132 g          109 t
ORIGIN      
        1 acatgggaag agggtacaac gcagagtaca tggggtgatc acgactcctc aggtcacctt
       61 ctcacaatga ggctccctgc tcagctcctg ggactgctaa tgctctggct ccctgggtcc
      121 agtggggaca ttgtgatgac ccagactcca ctctccctgc ccgtcaccct tggagagccg
      181 gcctccatct cctgcaggtc tagtcagagc ctcttggatg gtgaggatgg aaacacctat
      241 ttggaatggt acctgcagaa gccaggccag tctccacagc tcttgattta tgaggtttcc
      301 aaccgggcct ctggagtccc agacaggttc agtggcagtg ggtcagacac tgatttcaca
      361 ctgaaaatca gcagagtgga ggctgaggat gttgggattt attactgcat gcaagctcta
      421 gagtttcctc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007598             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:6605:10085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007598
VERSION     KCVT01007598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:6605:10085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85123.1"
                     /translation="CMQAREFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcact cttggagagc cggcctccat ctcctgcatg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atgtggaatg gtacctgcag aagccagacc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc gagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007599             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:13470:8123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007599
VERSION     KCVT01007599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13470:8123"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85124.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007600             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:26087:9862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007600
VERSION     KCVT01007600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:26087:9862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85125.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007601             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22486:9944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007601
VERSION     KCVT01007601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22486:9944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85126.1"
                     /translation="CQQYYDLFWTF"
     J_segment       389..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          101 a          119 c          117 g           91 t
ORIGIN      
        1 acatgggggg gaggaactgc tcagttagga cccagaggga accatggaag ccccagcaca
       61 gcttctcttc ctcctgctgc tctggatccc agataccgcc ggagaaattg tactgacgca
      121 gtctccagcc accctgtctt tgtctccagg ggaaacagcc accctctcct gcagggccag
      181 tgagtatgtt ggcagccact tagcctggta ccagcagaaa cctgggcagg cccccaagct
      241 ccttgtccac agtatagact tcagggccac tggcatccca gacaggttca gtggcagcgg
      301 gtctaggaca gagttcactc tcaccattag aagtctggag cctgaagatg ttggagttta
      361 tcactgtcag cagtattatg acttgttttg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01007602             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:6739:10450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007602
VERSION     KCVT01007602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6739:10450"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85127.1"
                     /translation="CQQGHTYPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           97 a          121 c          106 g           96 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcacgatcac ttgccaggcg agtcaaggca
      181 ttggcaagac tttaagttgg tatcagcaga aaccagggaa agcccctaat ctcctgatct
      241 atagggcatc cagtttgcaa ggtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtca tacttaccca ttcactttcg gccccgggac caaactggat atcaaacgag
//
LOCUS       KCVT01007603             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9814:22322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007603
VERSION     KCVT01007603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9814:22322"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85128.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          124 c          117 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattgctgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007604             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11841:5486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007604
VERSION     KCVT01007604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11841:5486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85129.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          128 c          111 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc accacaaacc tgggcaggct cccaacctcc
      241 tcctctatgg tgcatccacc agggccgccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007605             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15815:9361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007605
VERSION     KCVT01007605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15815:9361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85130.1"
                     /translation="CMQALEFPLTL"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          118 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaagat ggaaacacct atttgcactg gtacctgaag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactctc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007606             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16295:15065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007606
VERSION     KCVT01007606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16295:15065"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85131.1"
                     /translation="CQQVYSYPCSF"
     J_segment       382..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          107 c          108 g          104 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccatc
      121 tgccttgtct gcatctgtag gagacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatgataat ttagcgtggt ttcagcagaa agcagggaaa gcccctaaac tcctgatcta
      241 tactgcatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagtctgca gcctgaagat tctgcagttt attactgtca
      361 acaggtttat agttacccgt gcagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007607             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25219:11777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007607
VERSION     KCVT01007607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25219:11777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85132.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007608             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7908:5837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007608
VERSION     KCVT01007608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7908:5837"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..443
                     /note="immunoglobulin light chain variable region"
     V_region        104..443
     V_segment       104..406
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85133.1"
                     /translation="CMQTLEFPLTF"
     J_segment       407..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT           94 a          121 c          124 g          107 t
ORIGIN      
        1 acatggggtg actgatcacg actcctcagg tcaccttctc acaatgaggc tccctgctca
       61 gctcctggga ctgctaatgc tctggctccc tggatccggt ggggacattg tgatgaccca
      121 ggctccactc tccctgcccg tcacccttgg agagccggcc tccatctcct gcaggtctag
      181 tcagagcctc ttggatggtg aggatggaaa cacctatttg gattggtacc tgcagaagcc
      241 aggccagtct ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga
      301 caggttcagt ggcagtgggt cagacactga tttcacactg aaaatcagca gagtggaggc
      361 tgaggatgtt ggggtttatt actgcatgca aactctagag tttcctctca ctttcggcgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01007609             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:8730:16845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007609
VERSION     KCVT01007609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8730:16845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85134.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007610             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:20759:5659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007610
VERSION     KCVT01007610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20759:5659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..363
                     /note="immunoglobulin light chain variable region"
     V_region        84..363
     V_segment       84..326
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85135.1"
                     /translation="CQQDFDWPPTF"
     J_segment       329..363
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>366
                     /gene="IGKC"
BASE COUNT           86 a          108 c           98 g           74 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagctcca gcacagcttc
       61 tcttcctcct gctactctgg atcccagggg aaagagccac cctctcctgc agggccagtc
      121 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      181 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      241 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      301 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      361 aacgag
//
LOCUS       KCVT01007611             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:19165:13083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007611
VERSION     KCVT01007611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19165:13083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85136.1"
                     /translation="CQQYDSDSLTF"
     J_segment       378..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          102 a          115 c          108 g           93 t
ORIGIN      
        1 acatggggga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctagga
       61 ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac tcaggacatt
      181 cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc cttgatctat
      241 tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta ttactgtcaa
      361 caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01007612             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:23708:10990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007612
VERSION     KCVT01007612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23708:10990"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..385
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85137.1"
                     /translation="CLQYKSYPLTF"
     J_segment       386..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>425
                     /gene="IGKC"
BASE COUNT          105 a          113 c          107 g          100 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ttgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atcacttgcc gggcaagtca
      181 ggatattagc acttatttaa attggtttca gcagaaacca gggaaagccc ctagactcct
      241 gatctatgct tcatccagtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg cgacttatca
      361 ctgtctacag tataaaagtt accctctcac tttcggcgga gggaccaagg tggagatcag
      421 aagag
//
LOCUS       KCVT01007613             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11880:2778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007613
VERSION     KCVT01007613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11880:2778"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85138.1"
                     /translation="CQQYNSLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          107 a          109 c          110 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tctgggggac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gatatttaaa ttggtatcag cagaaaccgg ggaaagcccc taagttcctg
      241 atctattatg taaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattat
      361 tgtcaacagt ataatagttt accgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007614             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:13489:11287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007614
VERSION     KCVT01007614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13489:11287"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85139.1"
                     /translation="CQQYSSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          109 c          109 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcacaat cacttgccgg gcaagtcagg
      181 gcattagcaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctga
      241 tgtattatac aaaccgcttg gaaagtggga tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tggaacctga tgattttgca acttattact
      361 gtcaacagta tagttcttta ccgtggacgt tcggccaagg gaccaaggtg gaattcaaac
      421 gag
//
LOCUS       KCVT01007615             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16741:13802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007615
VERSION     KCVT01007615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16741:13802"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85140.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagagacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007616             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:13015:9525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007616
VERSION     KCVT01007616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13015:9525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85141.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aaaccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctttggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007617             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:10969:15188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007617
VERSION     KCVT01007617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10969:15188"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85142.1"
                     /translation="CQQHNGYPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          108 a          118 c          108 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 ttcatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattacg aatgatttag cctggtatca acagaaacca ggtaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ttgtcaacag cataatggat accctccgac gttcggccaa gggaccaggg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007618             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22343:14966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007618
VERSION     KCVT01007618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22343:14966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85143.1"
                     /translation="CQQYDSDPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          112 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctggagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgctcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01007619             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:25023:4732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007619
VERSION     KCVT01007619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25023:4732"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..245
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85144.1"
                     /translation="CQQYNSEPRTF"
     J_segment       253..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           77 a           70 c           81 g           62 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgtcgggcg agtcagggca ttcgcagtta
       61 tttagcgtgg tatcagcaga aaccagggaa acccccgaag cccttgatct attacgcgtc
      121 cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtataa
      241 cagtgagccg cgcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007620             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13957:13689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007620
VERSION     KCVT01007620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13957:13689"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85145.1"
                     /translation="CQQYNTDPHNF"
     J_segment       389..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          113 c          107 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattagtag ttttttagcg tggtatcagc agaatccagg gaaagccccg aaggccttga
      241 tctattacgc atccatattg gaaaatgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca acttattatt
      361 gtcaacagta taacactgac ccgcacaatt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007621             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10162:4743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007621
VERSION     KCVT01007621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10162:4743"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85146.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          124 g          104 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggact ggtacctgca gaagccgggc
      241 cagtctccac aggtcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga ctctgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007622             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13279:8947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007622
VERSION     KCVT01007622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13279:8947"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85147.1"
                     /translation="CQHSHGSPITF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           96 t
ORIGIN      
        1 acagggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcagg gcaagtgaga
      181 acgtttacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aaggtcctga
      241 tctatgctgc atccactttg caaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggactgattt cactctcacc atcagcagcc tgcagcctga agatgttgca acttattact
      361 gtcagcatag tcatggatcc cctatcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007623             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11508:15897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007623
VERSION     KCVT01007623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11508:15897"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85148.1"
                     /translation="CQQHDNAPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          116 c          116 g           85 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc agagccagtc
      181 agagtattaa cgactggttg gcctggtatc aacagagacc agggaaggcc cctaagctcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc aaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc agcatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcagca gcatgacaat gccccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007624             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:3074:9379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007624
VERSION     KCVT01007624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3074:9379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85149.1"
                     /translation="CQQYDNDPFTF"
     J_segment       381..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          115 c          108 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg ggtctgggac
      301 agaattcact ctcaccatca gcagcctaca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac aatgacccgt tcactttcgg tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01007625             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:21813:7549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007625
VERSION     KCVT01007625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21813:7549"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85150.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctaatcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggagtgg cacctgcaga agccaggcca
      241 gtctctacaa ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatttctgca tgcaggctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007626             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9392:15115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007626
VERSION     KCVT01007626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9392:15115"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85151.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 aacctcctgg atagtgagga tggaaacacc tatttgcact ggtacctgaa gaagccaggc
      241 cagtctccac agctcttaat ttatgaagtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cattgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007627             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21477:9882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007627
VERSION     KCVT01007627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21477:9882"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..349
                     /note="immunoglobulin light chain variable region"
     V_region        10..349
     V_segment       10..312
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <289..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85152.1"
                     /translation="CMQALEFPWTF"
     J_segment       313..349
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>352
                     /gene="IGKC"
BASE COUNT           80 a           88 c          104 g           80 t
ORIGIN      
        1 acatgggggg acattgtgat gacccagact ccagtctccc tgcccgtcac cctgggagag
       61 ccggcctcca tctcctgcag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      121 tatttggaat ggcacctgca gaggccaggc cagtctccac agctcttgat ttatgaggtt
      181 tcctatcggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      241 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      301 ctagagttcc cttggacgtt cggccaaggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007628             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24080:14790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007628
VERSION     KCVT01007628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24080:14790"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85153.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcactttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01007629             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:10793:12933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007629
VERSION     KCVT01007629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10793:12933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85154.1"
                     /translation="CQQHNSYPLTF"
     J_segment       387..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT          107 a          121 c          109 g           89 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 aggggattac caatgattta gcctggtatc agcagacacc agggaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggaaaatg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttc gcaacttatt
      361 actgtcaaca gcataatagt tacccactca ctttcggcgg agggaccaag gtggagatca
      421 gacgag
//
LOCUS       KCVT01007630             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:15769:12717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007630
VERSION     KCVT01007630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15769:12717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..273
                     /note="immunoglobulin light chain variable region"
     V_region        8..273
     V_segment       8..240
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85155.1"
                     /translation="CMQALEFPRTF"
     J_segment       242..273
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        274..>280
                     /gene="IGKC"
BASE COUNT           68 a           63 c           84 g           65 t
ORIGIN      
        1 acatgggggt ctagtcagag tctcttggat agtgcggatg gaaacaccta tttggactgg
       61 tacctgcaga agccaggcca gtctccacag ctcttgattt atgaggtctc cgaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt ggctcagaca ctgatttcac actgaaaatc
      181 agcagagtgg aggctgaaga tgttgggatt tattactgca tgcaagctct agagtttcct
      241 cggacgttcg gccaggggac caaggtggaa atcgaacgag
//
LOCUS       KCVT01007631             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:4931:9280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007631
VERSION     KCVT01007631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4931:9280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..382
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85156.1"
                     /translation="CLQGYSPPWTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          102 a          117 c          111 g           93 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct tctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcttccct gtctgcatcg gtaggagaca gagtcaccat cccttgccgg gcaagtcagg
      181 acattagcga ttatttaagt tggtatcagc agaaaccagg aaaacctcct aagcgcctga
      241 tctatgctgc atccagtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagagtt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacaggg ttatagtccc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaacc
      421 gag
//
LOCUS       KCVT01007632             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16146:11702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007632
VERSION     KCVT01007632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16146:11702"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85157.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          115 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007633             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18642:7742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007633
VERSION     KCVT01007633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18642:7742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85158.1"
                     /translation="CMQSLEIPPTF"
     J_segment       404..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtggggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagattcc tcccactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007634             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:22276:15007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007634
VERSION     KCVT01007634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22276:15007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85159.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          114 c          113 g           96 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaagtgtg acatccagat gacccagtct
      121 ccatcctcct tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagacaccag gaaaagcccc gaagcctttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggattt
      301 gggacggaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007635             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:24095:6811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007635
VERSION     KCVT01007635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24095:6811"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85160.1"
                     /translation="CMQSLELPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          122 c          118 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtggtg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcgtccat ctcctgtagg tctagtcaga
      181 gcctcgtgga tagtgaggat ggaaacacct atttggaatg gttcctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagcttcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007636             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:17193:14264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007636
VERSION     KCVT01007636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17193:14264"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85161.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          111 a          118 c          102 g           94 t
ORIGIN      
        1 acatgggagg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaacccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaggattttg caacttatta
      361 ctgtcaacaa tataacagtg acccattcac tttcggcccc gggaccaaac tggataccaa
      421 acgag
//
LOCUS       KCVT01007637             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13079:2924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007637
VERSION     KCVT01007637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13079:2924"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85162.1"
                     /translation="CQQHNGYPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          109 a          119 c          108 g           90 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 aggacattac gaatgattta gcctggtatc aacagaaacc aggtaaagcc ccgaagcccc
      241 tgatctatta cgcatccaat ttggagagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 attgtcaaca gcataatgga taccctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007638             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18701:7009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007638
VERSION     KCVT01007638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18701:7009"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85163.1"
                     /translation="CQQYTSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          121 c          104 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtgaggacgt
      181 tagcagtcat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttttgcaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgacgac tttgcaactt atcactgtca
      361 acagtacact agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007639             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14911:6080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007639
VERSION     KCVT01007639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14911:6080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85164.1"
                     /translation="CQQHNSYPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          121 c           98 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggtat
      181 tacgaattct ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacacatcc aatttagaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagcataat agttacccat tcactttcgg ccccgggacc aaactggata acaaacgag
//
LOCUS       KCVT01007640             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:11505:15252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007640
VERSION     KCVT01007640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11505:15252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85165.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc accctcggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccatccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg agtttattac tgcatgcaag ctctagaatt tccgctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007641             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15932:13875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007641
VERSION     KCVT01007641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15932:13875"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85166.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacactta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007642             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:8329:19937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007642
VERSION     KCVT01007642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8329:19937"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85167.1"
                     /translation="CQQGSPFPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          110 a          113 c          108 g           95 t
ORIGIN      
        1 acatgggggc atgagcaaaa ctgacaagtc aaggcaggaa gatgttgtct ccatcacaac
       61 tcattgggtt tctgctgctc tgggttccag cctccaaggg tgaaattgtg ctgactcagt
      121 ctccagcctt tcggtctgtg actctaaagg agaaagtcac catcacctgc caggccagtc
      181 agagcattgg taatagctta cactggtacc agcagaaacc ggatcagtct ccaaagctcc
      241 tcatcaaata tgcttcccag tccatctcag gggtcccctc aaggttcagt ggcagtggat
      301 ctgggacaga tttcaccctc accatcaaca gcctggaagc tgaagatgct gcgacgtatt
      361 actgtcagca gggaagtcct ttcccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007643             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:9613:4205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007643
VERSION     KCVT01007643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9613:4205"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85168.1"
                     /translation="CMQALEFPFTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           91 a          122 c          118 g          109 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctctttgat attgaggagg ggaccaccta tttggaatgg tacctgcaga ggcctggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc aacagagtgg aggctgagga
      361 tggtggggtt tattactgca tgcaagctct agagtttcct ttcactttcg gcggagggac
      421 caaggtggag atcaagcgag
//
LOCUS       KCVT01007644             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9901:10810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007644
VERSION     KCVT01007644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9901:10810"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85169.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          120 c          124 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgctgg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgacttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgt atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007645             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10989:15920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007645
VERSION     KCVT01007645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10989:15920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..313
                     /note="immunoglobulin light chain variable region"
     V_region        114..313
     V_segment       114..275
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85170.1"
                     /translation="CMQALEFPWTF"
     J_segment       276..313
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           70 a           80 c           90 g           76 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc tcatgctctg gctccctgta tccagtgggg acattgtgat gacccagact
      121 ccacagctct tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt
      181 ggcggtgggt cagacactga tttcacactg aaaatcagca gagtggaggc tgatgatgtt
      241 ggggtttatt actgcatgca agctctagag tttccgtgga cgttcggcca agggaccaag
      301 gtggaaatca aacgag
//
LOCUS       KCVT01007646             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23439:4041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007646
VERSION     KCVT01007646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23439:4041"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85171.1"
                     /translation="CLQDIQLPLTF"
     J_segment       399..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           87 a          125 c          120 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttgggttcca accgggcctc tggagtccca gccaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgcaaatcag ccgggtggag gctgaggatg
      361 ttggcattta ttactgctta caagatatac agcttcctct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007647             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:14881:8143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007647
VERSION     KCVT01007647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14881:8143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..367
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85172.1"
                     /translation="CLQGDTSPFTF"
     J_segment       386..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           98 a          116 c          111 g           97 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctt ctgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcttccctg tctgcatcgg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattaacgat tatttaagtt ggtatcagca gaaaccagga aaacctcctc agcgcctgat
      241 ctatgctgca tccactttgg agagtggggt cccgtcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagtctgaa gattttgcga cttattactg
      361 tctacagggt gatacttccc cgtttacttt cggcggaggg acccaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007648             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15509:16466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007648
VERSION     KCVT01007648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15509:16466"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85173.1"
                     /translation="CMQSLEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          119 c          119 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cactggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacacata tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtctc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctaatttcac actgagaatc agtagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007649             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:22745:21686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007649
VERSION     KCVT01007649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22745:21686"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85174.1"
                     /translation="CQQGNSIPLTF"
     J_segment       386..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          113 c          104 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gtcccagtct
      121 ccatccgccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagta attatttaaa ttggtatcaa cagaaaccgg ggaaagcccc taaggtcctg
      241 atctattatg cagacagctt gtcaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcaacaat ttgcagcctg aagattttgc aacttattat
      361 tgtcaacagg gtaatagtat tccactcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgac
//
LOCUS       KCVT01007650             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24157:17833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007650
VERSION     KCVT01007650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24157:17833"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85175.1"
                     /translation="CMQAREFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          127 c          116 g          100 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttcga tagtgaggag gggaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca actcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgctggggt ttattactgc atgcaagctc gagagtttcc attcactttc ggccccggga
      421 ccaaactgga catcaaacga g
//
LOCUS       KCVT01007651             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18814:17539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007651
VERSION     KCVT01007651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18814:17539"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85176.1"
                     /translation="CQQYNSLPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          110 c          112 g          100 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattg agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcagggcgtt atcgtttatt taaattggta tcaacagaaa ccggggaaag cccctaagcc
      241 cctgatcttt tatgcaaacc gtttggaacg tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaagtta
      361 ttattgtcaa cagtataata gtttaccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01007652             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:6684:9877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007652
VERSION     KCVT01007652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6684:9877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..393
                     /note="immunoglobulin light chain variable region"
     V_region        80..393
     V_segment       80..363
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85177.1"
                     /translation="CLQGDSTPFTF"
     J_segment       370..393
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>404
                     /gene="IGKC"
BASE COUNT           95 a          109 c          107 g           93 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc ttctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcttccc tgtctgcatc
      121 ggtaggagac agagtcacca tcacttgccg ggcaagtcag gacattagcg attatttaag
      181 ttggtatcag cagaaaccgg gaaaagctcc taagcgccta atctatgctg catccacttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagagt tcactctcac
      301 catcagcagc ctgcagcctg aagattttgc gacttattac tgtctacagg gtgatagtac
      361 cccgttcact tttggccagg ggaccaaagt ggacgtcaaa cgag
//
LOCUS       KCVT01007653             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21420:7742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007653
VERSION     KCVT01007653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21420:7742"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85178.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007654             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:17394:18513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007654
VERSION     KCVT01007654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17394:18513"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85179.1"
                     /translation="CQHSFRTPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          116 c          109 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctaggactcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcaatg tcacttgcag ggctagtgag
      181 agcgttagca ccaaattaca ttggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctttgctg cgtccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 ggaacagatt tcactctcac catcagcagc ctgcagcctg aagatgtcgc aactttttac
      361 tgtcagcata gttttcgtac cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007655             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:9040:13998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007655
VERSION     KCVT01007655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9040:13998"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85180.1"
                     /translation="CLQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          123 c          120 g          106 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattatgatg actcagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca taggaatggg tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtgccagtgg gtcaggcact gatttcacac tgaaaatcag ccgagtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac aacttccgct cactttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007656             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17026:17032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007656
VERSION     KCVT01007656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17026:17032"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85181.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccattt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007657             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:25483:10639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007657
VERSION     KCVT01007657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25483:10639"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..397
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85182.1"
                     /translation="CMQALEFPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           95 a          117 c          119 g          106 t
ORIGIN      
        1 acatggggtc gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcactcttg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cttggatagt gaggatggaa acacctattt ggaatggtac ctgcagaagc caggccagtc
      241 tccacagctc ttaatttatg aggtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007658             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19799:10588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007658
VERSION     KCVT01007658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19799:10588"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85183.1"
                     /translation="CLQYKSFPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          108 c          105 g          103 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtgg gagacactgt caccatcact tgccgggcaa gtcaggatat
      181 taacagttat ttaaattggt ttcagcagaa accagggaaa gccccaaagg tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc gtctaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtct
      361 acagtataaa agttttcctc tcactttcgg tggagggacc aaggtggata tcaaacgag
//
LOCUS       KCVT01007659             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17997:11403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007659
VERSION     KCVT01007659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17997:11403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85184.1"
                     /translation="CMQTLEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccggtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaaact ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007660             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:14881:9844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007660
VERSION     KCVT01007660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14881:9844"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85185.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag ctcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007661             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:18126:14989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007661
VERSION     KCVT01007661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18126:14989"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85186.1"
                     /translation="CIQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          121 c          116 g          107 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 tggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccaggctcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtctgaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtc tattactgca ttcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007662             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:4796:17422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007662
VERSION     KCVT01007662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4796:17422"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85187.1"
                     /translation="CVQALEFPWTF"
     J_segment       405..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          122 c          121 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctact
      181 cagagcctct tggatagtga ggatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacaactctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc tgacactgat ttcacactga aagtcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcgttcaa gctctagaat ttccgtggac gttcggccca
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01007663             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13638:10873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007663
VERSION     KCVT01007663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13638:10873"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..401
                     /note="immunoglobulin light chain variable region"
     V_region        99..401
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85188.1"
                     /translation="CQQGYSYPFTF"
     J_segment       384..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           87 a          118 c          100 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcac tagtttaagt tggtatcagc agaaaccagg gaaagcccct aaactcctca
      241 tctatagggc atccagtttg caaagtggga ttccctctcg gttcagcggc agtgtatctg
      301 ggacggcttt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac cccttcactt tcggccccgg g
//
LOCUS       KCVT01007664             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8553:7013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007664
VERSION     KCVT01007664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8553:7013"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85189.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007665             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14171:4721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007665
VERSION     KCVT01007665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14171:4721"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85190.1"
                     /translation="CMQALEFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          104 t
ORIGIN      
        1 acatgggtga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gcacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgacgttt ccagccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ctacagtttt ggccagggga
      421 ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007666             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12781:8531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007666
VERSION     KCVT01007666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12781:8531"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..403
                     /note="immunoglobulin light chain variable region"
     V_region        112..403
     V_segment       112..365
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <343..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85191.1"
                     /translation="CMQPLEFPWTF"
     J_segment       366..403
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>406
                     /gene="IGKC"
BASE COUNT           92 a          104 c          113 g           97 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtgc tgacccagac
      121 tccatctcct gcaggtctag tcagagcctc ttggatagtg aggatggaaa cacctatttg
      181 gaatggtacc tccagaagcc aggccagtct ccacatctct tgatttatga ggtttccaac
      241 cgggcctctg gagtcccaga caggttcagt ggcagtgggt cagacactga tttcacactg
      301 aaaatcagca gagtggaggc tgaggatgtt ggggtttatt actgcatgca acctctagag
      361 tttccgtgga cgttcggcca ggggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01007667             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17175:10812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007667
VERSION     KCVT01007667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17175:10812"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85192.1"
                     /translation="CMQSLEIPPSF"
     J_segment       411..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           94 a          121 c          124 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct gggtccagtg gggacattgt gatgacgcag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtgg ggatggaaac acctatttgg attggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaccc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gcgtttatta ctgcatgcaa tctctagaga ttcctcccag tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01007668             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24336:7820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007668
VERSION     KCVT01007668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24336:7820"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..401
                     /note="immunoglobulin light chain variable region"
     V_region        110..401
     V_segment       110..364
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85193.1"
                     /translation="CMQALEFPLTF"
     J_segment       367..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           94 a          101 c          112 g           97 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 catctcctgt aggtctagtc agagcctctt ggatagtgag gatggaaata cctatttgga
      181 atggcaccgg cagatgccag gccagtctcc acagctcttg atttatgagg tttccaaccg
      241 ggcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa
      301 aatcagcaga gtggaggctg aggatgttgg ggtttattac tgcatgcaag ctctagagtt
      361 tcctctgacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007669             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:19883:18692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007669
VERSION     KCVT01007669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19883:18692"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85194.1"
                     /translation="CQQYNALPLTF"
     J_segment       386..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>423
                     /gene="IGKC"
BASE COUNT          107 a          110 c          109 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagactt cactctcacc atcagcagcc tgcaacctga ggattttgca acttattact
      361 gtcaacagta taatgcttta ccgttgacgt tcggccaagg gaccagggtg gaaatcaaag
      421 gag
//
LOCUS       KCVT01007670             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15591:18344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007670
VERSION     KCVT01007670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15591:18344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85195.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           94 a          119 c          126 g          106 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt cgccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gggacattgt gatgacccag
      121 actccactct ccctgtccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatggtga ggatggaaac acctacttgg aatggtattt gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaagc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc aggcactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatca ctgcatgcaa gctctagagt ttcctctcac tttcggcgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01007671             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7624:6424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007671
VERSION     KCVT01007671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7624:6424"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..407
                     /note="immunoglobulin light chain variable region"
     V_region        103..407
     V_segment       103..386
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85196.1"
                     /translation="CQQYNDVLFTF"
     J_segment       387..407
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>427
                     /gene="IGKC"
BASE COUNT           97 a          125 c          115 g           90 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggatccca gataccgccg gagaaattgt aatgacgcag
      121 tctccagcca ccctgtcttt gtctccaggg gaaacagcca ccctctcctg ccgggccagt
      181 gagagtgttg gcaactactt agcctggtac cagcagaaac ctggccaggc tcccaagctc
      241 cttgtccatg gtgcatactt cagggccgct ggcatcccag acaggttcag tggcagcggg
      301 tctaggacag aattcactct caccattagc agcctggagc ctgaagatgt tggagtttat
      361 cactgtcagc agtataatga cgtcctattc actttcggcc ccgggacgga agtggacatc
      421 aagcgag
//
LOCUS       KCVT01007672             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:9901:15770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007672
VERSION     KCVT01007672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9901:15770"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85197.1"
                     /translation="CLQFKSYPNSF"
     J_segment       384..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          102 a          115 c          105 g          100 t
ORIGIN      
        1 acatgggggt cagacacagt caggacacag cttggacatg agggcccccg ctcatctcct
       61 agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga ctcagtctcc
      121 atcttccctg tctgcatctg taggagacac tgtcaccatc acttgccggg caagtcagag
      181 tattagtact catttaagtt ggtttcagca gaaaccaggg aaagccccta agctcctcat
      241 ctatgctgca tccagtttgg ccggtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tctacagttt aaaagttacc cgaacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007673             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:17294:10313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007673
VERSION     KCVT01007673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17294:10313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85198.1"
                     /translation="CQQNSNWPLTF"
     J_segment       388..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          100 a          126 c          115 g           86 t
ORIGIN      
        1 acatgggggg aggaactgct cagttaggac ccagagggaa ccatggaagc cccagcacag
       61 cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt gatgacgcag
      121 tctccagcca ccctgtcctt gtctccagga gaaagagcca ccctctcctg cagggccagt
      181 cagagtgtca gtagcagctt agcctggtac caacaaagac ctgggcaggc tcccaggctc
      241 ctcatctatg gtgcatccac cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag acttcactct caccatcacc agcctggagc ctgacgatgt tgcagtttat
      361 tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01007674             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:6896:14541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007674
VERSION     KCVT01007674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6896:14541"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85199.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctacatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007675             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:19651:12548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007675
VERSION     KCVT01007675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19651:12548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..456
                     /note="immunoglobulin light chain variable region"
     V_region        117..456
     V_segment       117..419
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85200.1"
                     /translation="CMQSLEFPLTF"
     J_segment       420..456
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>459
                     /gene="IGKC"
BASE COUNT          102 a          121 c          128 g          108 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggatc acgactcctc aggtcacctt ctcacaatga
       61 ggctccctgc tcagctcctg ggactgctaa tgctctggct ccctggatcc agtggggaca
      121 ttgtgatgac ccagactcca ctctccctgg ccgtcaccct tggagagccg gcctccatct
      181 cctgcaggtc tagtcagagc ctcttggata gtgaggatgg aaacacctat ttggaatggt
      241 acctgcagaa gccaggccag tctctagagc tcttgattta tgaggtttcc aaccgggcct
      301 ctggagtccc agacaggttc agtggcagtg ggtcagacac tgatttcaca ctgaaaatca
      361 gcagagtgga ggctgaggat gttggggttt attactgcat gcaatctcta gagtttcctc
      421 tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007676             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:7739:19426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007676
VERSION     KCVT01007676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7739:19426"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85201.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGKC"
BASE COUNT           91 a          120 c          125 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccaggctc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcagacga g
//
LOCUS       KCVT01007677             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:21972:15468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007677
VERSION     KCVT01007677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21972:15468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-13"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85202.1"
                     /translation="CLQYNSSPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          110 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacata gcatggacat gagggtccct gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgccgg gcgagtcaga
      181 ctattagcag ctggttagac tggtatcagc agaaaccagg gaaagcccct aacctcctga
      241 tctttaaggt atccagtttg caaagtgggg tcccctcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattatt
      361 gtctacagta caatagtagc ccgctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007678             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:22115:18310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007678
VERSION     KCVT01007678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22115:18310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85203.1"
                     /translation="CQQYNSLPRTF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          108 a          111 c          109 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtca atatttaaat tggtatcagc agaaaccggg gaaagcccct aaggtcctca
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta cctcggacgt tcggccaggg gaccaaggtg gaaatcagac
      421 gag
//
LOCUS       KCVT01007679             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:11142:15195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007679
VERSION     KCVT01007679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11142:15195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85204.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaggatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007680             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19506:6492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007680
VERSION     KCVT01007680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19506:6492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85205.1"
                     /translation="CQQYNSDPYTF"
     J_segment       379..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          104 a          112 c          109 g           93 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc caggtgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagaagttat ttagcgtggt atcaactgag accagggaaa gccccgaagg ccttaatcta
      241 ttacgcgacc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt atttctgtca
      361 acagtataac agtgacccgt acacttttgg ccaggggacc aagtggagat caaacgag
//
LOCUS       KCVT01007681             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25640:15298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007681
VERSION     KCVT01007681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25640:15298"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85206.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          110 c          107 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtagtagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtta ttatttaaat tggtatcaac agaaaccggg gaaagcccct aaggtcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca agtcattact
      361 gtcaacaata taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007682             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:20909:6600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007682
VERSION     KCVT01007682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20909:6600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85207.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          122 c          115 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007683             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9332:4187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007683
VERSION     KCVT01007683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9332:4187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..416
                     /note="immunoglobulin light chain variable region"
     V_region        96..416
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85208.1"
                     /translation="CLQYKSYPFTF"
     J_segment       380..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>420
                     /gene="IGKC"
BASE COUNT          104 a          113 c          102 g          101 t
ORIGIN      
        1 acatggggga gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcttgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgca ggagacactg tcaccatcac ttgccgggca agtcagggta
      181 ttggtaccta tttaaattgg tttcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc tagtctggaa agtggggtcc catcaaggtt cagcggcagt ggatttggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 tacagtataa aagttatcca ttcaccttcg gccccgggac caaactggat atcaaaggag
//
LOCUS       KCVT01007684             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:7575:17412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007684
VERSION     KCVT01007684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7575:17412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..276
                     /note="immunoglobulin light chain variable region"
     V_region        8..276
     V_segment       8..238
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85209.1"
                     /translation="CQQYDSDPFTF"
     J_segment       241..276
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>279
                     /gene="IGKC"
BASE COUNT           72 a           67 c           77 g           63 t
ORIGIN      
        1 atgggagagt caccatcact tgtcgggcga gtcagggcat tcgcagttat ttagcgtggt
       61 atcagcagaa accagggaaa gccccgaagc ccttgatcta ttacgcgtcc agtttggaaa
      121 gtggggtccc atcaaggttc agcggcggtg gatctgggac agaattcact ctcaccatca
      181 gcagcctgca gcctgaagat tttgcaactt attactgtca acagtatgac agtgacccgt
      241 tcactttcgg tggagggacc aaggtagaca tcaaacgag
//
LOCUS       KCVT01007685             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21588:10859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007685
VERSION     KCVT01007685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21588:10859"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85210.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc tcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007686             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:20570:10756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007686
VERSION     KCVT01007686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20570:10756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..377
                     /gene="IGKV3-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85211.1"
                     /translation="CYQHSRGWAF"
     J_segment       378..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>416
                     /gene="IGKC"
BASE COUNT           97 a          121 c          115 g           83 t
ORIGIN      
        1 acatggggtg ctaggttagt acccagaagg aaccatggaa gccccagctc agcttctctg
       61 ccttctgcta ctctggctcc caggtaccac cggacaaatt atattgacac agtctccagc
      121 caccctgtct ttggcaccag gggaaagagc cactctctcc tgcagggcca gtgagaatgt
      181 tggcagctac ttagcctggt accagcagaa ccctgggcag gctcccaggc tcctcgtcca
      241 cagtgcgtcc agcagggcca ctgacatccc agacaggttc agtggcagtg ggtctcggac
      301 agagttcacc ctcaccatca gcagtctgga gcctgaagat gttggagtct attactgcta
      361 tcaacatagc agggggtggg cgttcggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01007687             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16352:14284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007687
VERSION     KCVT01007687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16352:14284"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85212.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcaccttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01007688             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21491:3393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007688
VERSION     KCVT01007688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21491:3393"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..313
                     /note="immunoglobulin light chain variable region"
     V_region        127..313
     V_segment       127..274
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85213.1"
                     /translation="CQQYDSDLFTF"
     J_segment       278..313
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           76 a           88 c           78 g           74 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc
      181 ggcagtggtt ctgggacaga attcactctc accatcaaca gcctgcagcc tgaagatttt
      241 gcaacttatt actgtcaaca gtatgacagt gacctgttca ctttcggtgg agggaccaag
      301 gttgagatca aacgag
//
LOCUS       KCVT01007689             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:3397:11175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007689
VERSION     KCVT01007689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:3397:11175"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..320
                     /note="immunoglobulin light chain variable region"
     V_region        7..320
     V_segment       7..283
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <260..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85214.1"
                     /translation="CQQGDSYPRTF"
     J_segment       285..320
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>323
                     /gene="IGKC"
BASE COUNT           87 a           80 c           82 g           74 t
ORIGIN      
        1 acatgggatg tcccagtctc cttcctccct gtctgcatct gtgggagaca gagtcaccat
       61 cacttgccgg gcaagtcagg acattagaga ttatttaaat tggtatcagc agcaaccggg
      121 gaaagcccct aaactcctga tgtattatgc aaacagtctg gcaagtggag tcccatcaag
      181 gttcagcggc agtggatctg ggacagaatt cagtctcacc atcagcagcc tgcagcctga
      241 agattttgca acttattact gtcaacaggg tgacagttat cctcggacgt tcggccaagg
      301 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007690             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:12483:13180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007690
VERSION     KCVT01007690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12483:13180"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..390
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85215.1"
                     /translation="CLQSKNSPWTF"
     J_segment       391..428
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT          100 a          113 c          114 g          104 t
ORIGIN      
        1 acatggggag cagcctctag ttcagctctc agaaatgggg tcctgggctc ctttcctgtg
       61 gatcctcctg ctctgtgctc caggatgcaa tggggacatt gtgctgaccc agtctccagc
      121 ctctttggac gtgtctccag ggcagagggc caccatcacc tgcagagcca gtgagagtgt
      181 cagtttgttt ggaataagcc tcattcactg gtatcagctt aaaccaggac aacctcctaa
      241 actcctgatt taccaagcac tcaatacaga gactggggtc ccagtcaggt tcagcggcag
      301 tgggtctggg accgatttca ccctcacaat taatcctgtg gaagctgacg atgctgcaga
      361 ttatttctgt ctgcagagta agaattctcc gtggacgttc ggccaaggga ccaaggtgga
      421 aatcaaacga g
//
LOCUS       KCVT01007691             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:17953:9316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007691
VERSION     KCVT01007691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17953:9316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85216.1"
                     /translation="CHQYNNLPLTF"
     J_segment       365..401
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          103 a          108 c           98 g           95 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgcttc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag gacattaaca tttatttaaa
      181 ttggtatcag cagaaaccgg ggaaagcccc taagctcctg atctattatg caaatcgttt
      241 ggaaactggg gtcccgtcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcaacagc ctgcaacccg aagattttgc aacttattac tgtcaccagt ataataattt
      361 accactcact ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007692             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12813:14480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007692
VERSION     KCVT01007692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12813:14480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85217.1"
                     /translation="CMQSLEFPLSF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgtg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaatct ctagagtttc cgctcagttt cggtggaggg
      421 accaaggtgg acatcaaacg ag
//
LOCUS       KCVT01007693             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:17989:5879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007693
VERSION     KCVT01007693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17989:5879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85218.1"
                     /translation="CMQAREFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcactc ttggagagcc ggcctccatc tcctgcttgt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tctggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctcg agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007694             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8615:17930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007694
VERSION     KCVT01007694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8615:17930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85219.1"
                     /translation="CQQYYDLFWTF"
     J_segment       387..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          115 g           91 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgta ctgatgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agtatattgg cagccactta gcctggtacc agcagaagcc tgggcaggcc cccaagctcc
      241 ttgtccatag tacagacttc agggccactg gcatcccaga caggttcagt ggcagcgggt
      301 ctaggacaga gttcactctc accattagaa gtctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtattatgac ctgttttgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007695             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:10876:10740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007695
VERSION     KCVT01007695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10876:10740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..441
                     /note="immunoglobulin light chain variable region"
     V_region        99..441
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85220.1"
                     /translation="CMQALEFPPFTF"
     J_segment       404..441
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          124 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattattgc atgcaagctc tagagtttcc tccattcact ttcggccccg
      421 ggaccaaact ggagatcaaa cgag
//
LOCUS       KCVT01007696             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14855:7803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007696
VERSION     KCVT01007696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14855:7803"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85221.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          105 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007697             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:12403:20955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007697
VERSION     KCVT01007697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12403:20955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85222.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          113 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg cgtccgcttt ggaaagtggg gtcccatcaa gggtcagcgg cagcggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga cccgttcact ttcggtggag ggaccaaggt agagatcaaa
      421 cgag
//
LOCUS       KCVT01007698             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:18866:2544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007698
VERSION     KCVT01007698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18866:2544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..375
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85223.1"
                     /translation="CLQESNWSYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           96 a          119 c          118 g           85 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ccccagcaca gcttctcttc
       61 ctcctgctgc tctggctccc agatagtacc ggagaaatag tggtgacaca gtctccagcc
      121 accctgtctt tgtctccagg ggaaagagcc accctctcct gcagggccag tcagagtgtc
      181 aaaagcaggt tagcctggta ccagcagaaa cctgggcaag ctcccaggct cctcatgtat
      241 gatgcgtcca gcagggccac tggcatccca gacaggttca ctggcagcgg gtctgggcca
      301 gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcggttta tttctgtctt
      361 caggagagta actggtcgta cagctttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007699             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21829:4954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007699
VERSION     KCVT01007699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21829:4954"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85224.1"
                     /translation="CQQGYNFPFTF"
     J_segment       385..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          106 g           99 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc caggtgacgc agtctccatc
      121 ctccctgtcc gcatctgtag gagacacagt cacgatcact tgccaggcga gtcaaggcat
      181 tggcaaaaat ttaaattggt atcaacagaa accagggaaa gcccctaaac tcctgattta
      241 tagggcatcc agtttgcaaa gtggagttca ctctcggttt agcggcagtg gatccgggac
      301 ggatttctct ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat aatttcccgt tcacttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007700             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14613:13369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007700
VERSION     KCVT01007700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14613:13369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85225.1"
                     /translation="CQQHNNYSPTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          119 c          107 g           92 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctct tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccaccctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagca atgatttagc ctggtatcag ctgaaaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataataatta ctctcccact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007701             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15095:16311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007701
VERSION     KCVT01007701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15095:16311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85226.1"
                     /translation="CQQYNTLPFTF"
     J_segment       383..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>423
                     /gene="IGKC"
BASE COUNT          106 a          115 c          103 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga gattcagatg acccagtctc
      121 catcctccct gtctgcctct gtcggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcaa ttatttaaat tggtatcagc agagaccggg gaaagcccct aaactcctga
      241 tctattatgc atcccgtttg gaaaatgggg tcccatcaaa gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagtagtc tgcaatctga agattttgca gcttattact
      361 gtcagcagta taatacctta ccattcactt tcggccccgg gaccaaactg gaaatcagac
      421 gag
//
LOCUS       KCVT01007702             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:5890:11778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007702
VERSION     KCVT01007702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5890:11778"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85227.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          127 c          108 g           87 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtca tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc aacaccttaa cctggtacca acacaaacct gggcaggctc ccaaactcct
      241 cctctatggt gcatccacca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007703             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19780:20597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007703
VERSION     KCVT01007703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19780:20597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85228.1"
                     /translation="CQQGYSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          117 c          107 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccccgctc agctccttgg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgacgc agtctccatc
      121 ctccctgtcc gcatctgcag gagacacagt caccatcact tgccaggcga gtcaaggcat
      181 tggtaatact ttaaattggt atcaacagaa accggggaaa gcccctacac tcctgatcta
      241 tagggcatcc ggtttgcaaa gtgggactcc ctctcggttc agcggcagtg gatctgggac
      301 ggatttcact ctcaccatca gcagcctgca gcctgaagat tttgccactt attactgtca
      361 acagggttat agttatccgt acagttttgg ccaggggacc aaactggaga tcaaacgag
//
LOCUS       KCVT01007704             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:11314:8647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007704
VERSION     KCVT01007704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11314:8647"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85229.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagac
      181 cctcttggat ggtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007705             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:13082:16548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007705
VERSION     KCVT01007705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13082:16548"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85230.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          101 a          120 c          117 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattac tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgtcca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agaacccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01007706             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:16587:11579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007706
VERSION     KCVT01007706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16587:11579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..355
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85231.1"
                     /translation="SMHDSGGPTTF"
     J_segment       381..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           94 a          114 c          118 g           92 t
ORIGIN      
        1 acatgggggc tctgagcacc gcctgccagc atgttcttgg gagttcaggt gcagctcctc
       61 tggagcctgg ctttctggag ggcagtgagt ggagacatca tcctgaacca gacgccagca
      121 tccctgactg cacctccagg agagacagtc tccatctcct gccaagccag agcagatgta
      181 catggtgaaa tgtcttggat ccggataaac cttgaacaaa gacttgaacc ccttttatct
      241 catgtcacta ccttggcccc aggtgtcgca gcccggttca tcagcaaggg gagtggcacc
      301 agttatgttt tcagcatcag tgacctgcag cctggggact ctggggacta ttactccatg
      361 catgactctg gggggccaac cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01007707             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13054:5422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007707
VERSION     KCVT01007707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13054:5422"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85232.1"
                     /translation="CQQYNSLPYFF"
     J_segment       389..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          110 c          104 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattaacgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatag aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtactttt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007708             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14212:6815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007708
VERSION     KCVT01007708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14212:6815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85233.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          105 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtgga gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatagtgagg atggaaatac ctatttggaa tggcaccggc agatgccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagc tctagagttt cctctgacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007709             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16341:15145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007709
VERSION     KCVT01007709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16341:15145"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85234.1"
                     /translation="CMQSLEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaatctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007710             389 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16780:12719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007710
VERSION     KCVT01007710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 389)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16780:12719"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    65..386
                     /note="immunoglobulin light chain variable region"
     V_region        65..386
     V_segment       65..348
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <326..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85235.1"
                     /translation="CQHSFRTPYSF"
     J_segment       349..386
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>389
                     /gene="IGKC"
BASE COUNT           90 a          108 c          100 g           91 t
ORIGIN      
        1 acatgggggg gcctctgctc agctcctagg gctcctgctg ctctggctcc caggcgccag
       61 atgtgacatc cagatgaccc agtctccatc ctccctgtct gcatctgtag gagacagagt
      121 caatgtcact tgcagggcta gtgagagcgt tagcaccaaa ttacattggt atcagcagaa
      181 accagggaaa gcccctaagc tcctgatctt tgctgcgtcc actttgcaaa gtggggtccc
      241 atcaaggttc agcggcagtg gatctggaac agatttcact ctcaccatca gcagcctgca
      301 gcctgaagat gtcgcaactt tttactgtca gcatagtttt cgtaccccgt acagttttgg
      361 ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007711             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13344:8043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007711
VERSION     KCVT01007711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13344:8043"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85236.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT          104 a          113 c          110 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 taggagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacacatcc attttggaaa gtggggtccc atcaaggttc accggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc agagtggaga tccaacgag
//
LOCUS       KCVT01007712             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10350:8395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007712
VERSION     KCVT01007712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10350:8395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85237.1"
                     /translation="CQQHDDSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          111 a          118 c          109 g           88 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagtc
      181 aggatattaa tacctggttg gcctggtatc aacagaaacc aggaaaagcc cctaaactcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcggt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatatc gcaacatatt
      361 actgtcaaca gcatgatgat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007713             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11256:19311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007713
VERSION     KCVT01007713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11256:19311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85238.1"
                     /translation="CQQYNSLPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          110 c          113 g           99 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattg agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcagggcgtt aacgtttatt taaattggta tcagcagaaa ccggggaaag cccctaagcc
      241 cctgatcttt tatgcaaacc gtttggaacg tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcaagtta
      361 ttattgtcaa cagtataata gtttaccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01007714             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15194:9247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007714
VERSION     KCVT01007714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15194:9247"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85239.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          127 c          112 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcccccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007715             389 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9521:5051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007715
VERSION     KCVT01007715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 389)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9521:5051"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..386
                     /note="immunoglobulin light chain variable region"
     V_region        113..386
     V_segment       113..348
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85240.1"
                     /translation="CQQYNTLPYTF"
     J_segment       349..386
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>389
                     /gene="IGKC"
BASE COUNT          101 a          102 c           98 g           88 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacgttcag atgacccagt
      121 ctccatcact tgccgggcaa gtcaggacat taacgtttat ttaaattggt atcaccagaa
      181 accggggaaa gcccctaacc tcctgatcta ttatgcaaac cgtttggaaa atggggtccc
      241 gtcaaggttc agcggcagtg gatctgggac agaattcact ctcaccatca gcagcctgca
      301 acctgaagat tttgcgactt attactgtca acagtataat actttaccgt acacttttgg
      361 ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007716             389 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:16819:9282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007716
VERSION     KCVT01007716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 389)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16819:9282"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..386
                     /note="immunoglobulin light chain variable region"
     V_region        82..386
     V_segment       82..348
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85241.1"
                     /translation="CQQYDSDPLTF"
     J_segment       349..386
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>389
                     /gene="IGKC"
BASE COUNT           95 a          104 c          104 g           86 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctccatc ctccctgtct gcatctgtag gagacagagt
      121 caccatcact tgtcgggcga gtcagggcat tcgcagttat ttagcgtggt atcagcagaa
      181 accagggaaa gtcccgaagc ccttgatcta ttacgcgtcc actttggaaa gtggggtccc
      241 atcaaggttc agcggcagtg gatctgggac agaattcact ctcaccatca gcagcctgca
      301 gcctgaagat tttgcaactt attactgtca acagtatgac agtgacccgc tcactttcgg
      361 tggagggacc aaggtagaga tcaaacgag
//
LOCUS       KCVT01007717             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:10735:5581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007717
VERSION     KCVT01007717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10735:5581"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85242.1"
                     /translation="CQQVYSNPAF"
     J_segment       386..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          111 c          109 g           99 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc tgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg atatccaggt gacccagtct
      121 ccatctgcct tgtctgcatc tgtaggagac agagtcacca tctcttgccg ggcaagtcag
      181 aacatttata ggaatttagc gtggtatcag cagaaaccag ggaaagcccc taagctcctg
      241 atctttgctg catccagatt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcaac ctacagcctg aagattctgc aatttattac
      361 tgtcaacagg tttatagtaa cccggcgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01007718             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:22143:12799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007718
VERSION     KCVT01007718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22143:12799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85243.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt gacagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007719             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15444:5161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007719
VERSION     KCVT01007719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15444:5161"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85244.1"
                     /translation="CQQYDSDPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaagatt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaacc tattactgtc
      361 aacagtatga cagtgatccg ttcactttcg gtggggggac caaggtagac atcaaacgag
//
LOCUS       KCVT01007720             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:24530:15698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007720
VERSION     KCVT01007720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24530:15698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..435
                     /note="immunoglobulin light chain variable region"
     V_region        103..435
     V_segment       103..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85245.1"
                     /translation="CLQDIRVPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           85 a          124 c          125 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtggggg tgttgtgatg actcagactc
      121 cagtctccct agccgtcacc cctggagagc cggcctccat ctcctgcagg tccagtcaga
      181 gcctcctgca tactaatgga tacaccaatt tgttctggtt cctgcagaag ccaggccagt
      241 ctcctaagct cctgatctat ttcggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaggatg
      361 ttggggttta ttactgcttg caagatatac gcgttccgct caccttcggt ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007721             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:27140:10936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007721
VERSION     KCVT01007721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:27140:10936"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85246.1"
                     /translation="CQQDFGWPLTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          118 c          117 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctctga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007722             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:15824:5626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007722
VERSION     KCVT01007722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15824:5626"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85247.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctac agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007723             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:12672:3219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007723
VERSION     KCVT01007723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12672:3219"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-82"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85248.1"
                     /translation="CMQGTHLPWTF"
     J_segment       398..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           93 a          125 c          119 g          101 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgtt agtgctctgg ctccctgggt ccactggcga cactgtgatg acacagaccc
      121 cactctccct gcccgtcatc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctaca tagaaatgga tacacctatt tgtactggta cctgcagagg ccgggccagt
      241 ctccacagct cctgatgtat tttgtttcaa accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tacggatcag cagggtggag gctgaggata
      361 ttgggattta ttattgcatg caaggtacac accttccgtg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01007724             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:12093:13674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007724
VERSION     KCVT01007724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12093:13674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85249.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          121 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007725             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:11245:7592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007725
VERSION     KCVT01007725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11245:7592"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85250.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          117 c          123 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgttctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactgtccct gcccgtcacc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007726             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:10844:6373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007726
VERSION     KCVT01007726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10844:6373"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85251.1"
                     /translation="CQQNSNWPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          102 a          123 c          111 g           85 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagccccagc acagcttctc
       61 ttcctcctgc tgctctggct cccagatacc accggagaaa tagtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggagaaaga gccaccctct cctgcagggc cagtcagagt
      181 gtcagcagca gcgtagcctg gtaccagcaa aaacctgggc aggctcccag actcctcatc
      241 tatggtgcat ccaacagggc cactggcatc ccagacagat tcagtggcag tgggtctggg
      301 acagagttca ctctcaccat cagcagcctg gagcctgaag atgttgcact ttattattgt
      361 cagcagaata gtaactggcc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007727             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:22797:19392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007727
VERSION     KCVT01007727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22797:19392"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85252.1"
                     /translation="CQQHDNFPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          116 c          103 g           93 t
ORIGIN      
        1 acatggggag tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaac
      181 atattagcga ctggttggcc tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctatcgggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagct ttcagcctga agatatcgca acatattact
      361 gtcaacagca tgataatttc ccgtacattt ttgaccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01007728             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16333:7504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007728
VERSION     KCVT01007728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16333:7504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85253.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaaa
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007729             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15938:19143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007729
VERSION     KCVT01007729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15938:19143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85254.1"
                     /translation="CQQYNSDPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          114 c          107 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcgagtcagg
      181 gcattagaag ttatttagcg tggtatcagc agaaaccagg aaaagccccg aaggccttga
      241 tctattacgc atccatttta gagagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagtctga cgattttgca acttattact
      361 gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007730             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14035:9128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007730
VERSION     KCVT01007730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14035:9128"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    59..380
                     /note="immunoglobulin light chain variable region"
     V_region        59..380
     V_segment       59..343
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <320..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85255.1"
                     /translation="CQQDFGWPPTF"
     J_segment       346..380
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>383
                     /gene="IGKC"
BASE COUNT           88 a          109 c          103 g           83 t
ORIGIN      
        1 acatggggca gcacagcttc tcttcctcct gctactctgg atcccagata ccaccggaga
       61 aatagtgatg acgcagtctc cagccattct gtctttgtct ccaggggaaa gagccaccct
      121 ctcctgcagg gccagtcaga ctgttggcag cgccttagcc tggtaccagc agaaacctgg
      181 gcagactcac aaactcctca tttatggtgc atccagcagg gccaccggca tcccagacag
      241 gttcagtggc agtgggtctg gaacagagtt cactctcacc atcagtagtc cggagcctga
      301 ggatgttgga gtttattact gtcagcagga ttttggctgg cctccgacgt tcggccaagg
      361 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007731             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22045:15052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007731
VERSION     KCVT01007731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22045:15052"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85256.1"
                     /translation="CQQNSNWPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          122 c          114 g           86 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagcccc agcacagctt
       61 ctcttcctcc tgctgctctg gctcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggagaa agagccaccc tctcctgcag ggccagtcag
      181 agtgtcagca gcagtgtagc ctggtaccag caaaaacctg ggcaggctcc cagactcctc
      241 atctatggtg catccaacag ggccactggc atcccagaca ggttcagtgg cagtgggtct
      301 gggacagagt tcactctcac catcagcagc ctggagcctg aagatgttgc actttattat
      361 tgtcagcaga atagtaactg gcctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007732             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:18041:14068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007732
VERSION     KCVT01007732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18041:14068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85257.1"
                     /translation="CMQALEFPYSF"
     J_segment       401..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          121 c          119 g          103 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggagtgg cacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgacgtttc cagccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccc tacagttttg gccaggggac
      421 caaagtggag atcaaacgag
//
LOCUS       KCVT01007733             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:7668:7956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007733
VERSION     KCVT01007733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7668:7956"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85258.1"
                     /translation="CQQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          114 a          113 c          100 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tgggactcct gctgctctgg ctcccaggtg ccagatgtga caatcagatg acccagtctc
      121 caccctccct gtctgcctct gtaggagata gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtat ttatttaaat tggtatcaac aaaaaccggg gaaagcccct aacctcctga
      241 tctattatgg aaaccgtttg gaaagtgggg tcccaccaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacactt ttggccacgg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007734             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11925:14528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007734
VERSION     KCVT01007734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11925:14528"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85259.1"
                     /translation="CLQGDTAPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          113 c          112 g           96 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattaacg attatttaag ttggtatcag cagaaaccag gaaaacctcc taagcgccta
      241 atctatgctg catctagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc agtttattac
      361 tgtctacagg gtgatactgc cccgttcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007735             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13174:5881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007735
VERSION     KCVT01007735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13174:5881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85260.1"
                     /translation="CQQYNRFPLTF"
     J_segment       383..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          112 c          106 g           96 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcaggc
      181 cattagtagt tacttaaatt ggtatcagca aaagccgggg aaagccccaa agcccctgat
      241 ctattatgca aaccgtttgg aaaatggagt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgag gattttgcaa tttattactg
      361 tcaacaatat aataggtttc ctctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007736             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24607:10694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007736
VERSION     KCVT01007736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24607:10694"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85261.1"
                     /translation="CMQALDFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          119 c          121 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggagt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttttgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagtgt ggaggctgag
      361 gatgttgggg tctattactg catgcaagct ctagactttc cttacagttt tggccagggg
      421 accaaagtgg agattaaacg ag
//
LOCUS       KCVT01007737             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:20879:10271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007737
VERSION     KCVT01007737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20879:10271"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85262.1"
                     /translation="CMQSLDFPLTF"
     J_segment       401..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcagtctc tagattttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaatcga g
//
LOCUS       KCVT01007738             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:8975:19403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007738
VERSION     KCVT01007738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8975:19403"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85263.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          125 c          116 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccccggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007739             357 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18100:15587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007739
VERSION     KCVT01007739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18100:15587"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..354
                     /note="immunoglobulin light chain variable region"
     V_region        15..354
     V_segment       15..317
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <294..>326
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85264.1"
                     /translation="CMQALEFPWTF"
     J_segment       318..354
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        355..>357
                     /gene="IGKC"
BASE COUNT           82 a           89 c          105 g           81 t
ORIGIN      
        1 acatgggcag tggggacatt gtgatgaccc agactccagt ctccctgccc gtcaccctgg
       61 gagagccggc ctccatctcc tgcaggtcta gtcagagcct cttggatagt gaggatggaa
      121 acacctattt ggaatggcac ctgcagaggc caggccagtc tccacagctc ttgatttatg
      181 aggtttccta tcgggcctct ggagtcccag acaggttcag tggcagtggg tcagacactg
      241 atttcacact gaaaatcagc agagtggagg ctgaggatgt tggggtttat tactgcatgc
      301 aagctctaga gttcccttgg acgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01007740             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:13636:15480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007740
VERSION     KCVT01007740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13636:15480"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..405
                     /note="immunoglobulin light chain variable region"
     V_region        84..405
     V_segment       84..367
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <345..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85265.1"
                     /translation="CQHSFRTPYSF"
     J_segment       368..405
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT           97 a          113 c          105 g           93 t
ORIGIN      
        1 acatgggagg acacagcatg gacatgaggg cctctgctca gctcctaggg ctcctgctgc
       61 tctggctccc aggcgccaga tgtgacatcc agatgaccca gtctccatcc tccctgtctg
      121 catctgtagg agacagagtc accgtcactt gcagggctag tgagagcgtt ggcaccaaat
      181 tacattggta tcaacagaaa ccagggaaag cccctaagct cctgatcttt gctgcgtcca
      241 ctttgcaaag tggggtccca tcaaggttca gcggcagtgg atctggaaca gatttcactc
      301 tcaccatcag cagcctgcag cctgaagatg ttgcaacttt ttactgtcag catagttttc
      361 gtaccccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007741             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:7668:16109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007741
VERSION     KCVT01007741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:7668:16109"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85266.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          123 c          116 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggcc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007742             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14257:5906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007742
VERSION     KCVT01007742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14257:5906"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85267.1"
                     /translation="CLQFKTFPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           98 a          117 c          105 g          103 t
ORIGIN      
        1 acatggggag tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtaggagaca ctgtcaccat ctcttgccgg gcaagtcagg
      181 gtattagcag ttctttaagt tggtttcagc agaaaccagg gaaagcccct aagctcctca
      241 tctatgctgc atccactttg gctggtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagactt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtctacagtt taaaactttc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007743             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14130:13471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007743
VERSION     KCVT01007743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14130:13471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85268.1"
                     /translation="CQQYYSTPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT          103 a          112 c          123 g          101 t
ORIGIN      
        1 acatgggggc tacaacaggc aggcaggggc agcaagatgg tgtcacagac ccaagtcttc
       61 atttccctgt tgctctggat ctctggtgcc tgtggggaca ttgtgatgac ccagtcgcca
      121 gactccctgg ctgtgtctct gggagagagg gtcaccatca actgcaagtc cagccagagt
      181 cttttacgcg tctccaacaa taggaactac ttagcctggt atcagcagaa accagggcag
      241 gctcctaaat tgctcattta ctgggcatct acccgggaat tcgggatccc taaccgattc
      301 agtggcagtg gatctgggtc agatttcact ctcaccatca gtggcctgca ggctgaagat
      361 gtggcagtgt attactgtca gcagtattat agcactccgt ggacgttcgg ccaagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01007744             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19999:12286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007744
VERSION     KCVT01007744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19999:12286"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85269.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcccgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcac aagccaggcc
      241 agtctccaga gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagattg gaggctgagg
      361 atgttgggct ttattactgt atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga ggtcaaacga g
//
LOCUS       KCVT01007745             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21992:18590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007745
VERSION     KCVT01007745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21992:18590"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..386
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85270.1"
                     /translation="CQQYFSTPFTF"
     J_segment       387..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>427
                     /gene="IGKC"
BASE COUNT           98 a          127 c          111 g           91 t
ORIGIN      
        1 acatggggag aagagctgct cagttaggac ccagagagaa ccatggaaat cccagctcag
       61 cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat attgactcag
      121 tctccagcca cgctgtcttt gtctccaggg gaaagagcca ccctctcctg cagggccagt
      181 cagagagctg gtagcagctt agcctggtac cagcagaaac ctgggcaggc ccccaggctc
      241 ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag tggcagtggg
      301 tctgggacag agttcaccct caccatcagc agcctggagc ctgaagattt tgcagtgtat
      361 tactgtcagc agtattttag taccccattc actttcggcc ccgggaccaa actggatatc
      421 agacgag
//
LOCUS       KCVT01007746             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:7006:6607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007746
VERSION     KCVT01007746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7006:6607"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85271.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          128 c          110 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc accacaaacc tgggcaggct cccacgctcc
      241 tcctctatgg tgcatccacc agggccaccg gcatcccaga caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 tctgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007747             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:19900:16384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007747
VERSION     KCVT01007747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19900:16384"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..403
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85272.1"
                     /translation="CLQTKNSPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          104 a          120 c          118 g          102 t
ORIGIN      
        1 acatggggag gggccctgag gagcagcctc tagttcagct ctcagaaatg gggtcctggg
       61 ctcctttcct gtggatcctc ctgctctgtg ctccaggctg caatggggac attgtgctga
      121 cccagtctcc agcctctttg gccgtgtctc cagggcagag ggccaccatc acctgcagag
      181 ccagtgagag tgtcagtgtc tttggaataa acctcattca ctggtatcag cagaaaccag
      241 gacaacctcc taaatccctg atttaccaag catccaataa agacactgtg gtcccagcca
      301 ggttcagcgg cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaagctg
      361 acgatgctgc agattattac tgtctgcaga ctaagaattc tccgtggacg tttggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007748             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:24354:11042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007748
VERSION     KCVT01007748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24354:11042"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85273.1"
                     /translation="CEQYNSLPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          112 a          110 c          103 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattaaca tttatttaaa ttggtatcac cagaaaccgg ggaaagcccc taagctcctg
      241 atttattata caaatcgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtgaacaat acaatagttt accgtacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007749             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:18114:3871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007749
VERSION     KCVT01007749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18114:3871"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85274.1"
                     /translation="CQQYNSEPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          110 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagctt ggtatcagca gaaaccaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgagc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007750             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21191:12416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007750
VERSION     KCVT01007750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21191:12416"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85275.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          108 a          117 c          104 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcggcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01007751             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:14522:7723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007751
VERSION     KCVT01007751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14522:7723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85276.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          121 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007752             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19025:9948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007752
VERSION     KCVT01007752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19025:9948"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85277.1"
                     /translation="CMQALDFPYSF"
     J_segment       403..439
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttttgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactaatttc acactgaaaa tcagcagtgt ggaggctgag
      361 gatgttgggg tctattactg catgcaagct ctagactttc cttacagttt tggccagggg
      421 accacagtgg agattaaacg ag
//
LOCUS       KCVT01007753             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:14073:15892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007753
VERSION     KCVT01007753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14073:15892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85278.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc cgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007754             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:9553:17815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007754
VERSION     KCVT01007754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9553:17815"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..245
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85279.1"
                     /translation="CQQYDSDSLTF"
     J_segment       251..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           78 a           69 c           78 g           65 t
ORIGIN      
        1 acatggggta ggagacagag tcaccatcac ttgtcgggcg actcaggaca ttcgcagtta
       61 tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc
      121 cactttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtatga
      241 cagtgattca ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007755             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12047:7191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007755
VERSION     KCVT01007755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12047:7191"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85280.1"
                     /translation="CQQCNSFPFTF"
     J_segment       378..415
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          117 c           99 g           97 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctggga
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg catctgtagg agacagagtc accatcactt gccgggcaag tcgggacatt
      181 agcagttttt taaattggta tcagcataaa ccggggaaag cccctaagct cctgatcttt
      241 aatacaaacc atttggaaag aggggcccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcta cctgaggatt ttgcaaccta ttactgtcaa
      361 cagtgtaata gtttcccatt cactttcggc cccgggtcca aactggatat caaacgag
//
LOCUS       KCVT01007756             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11987:13773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007756
VERSION     KCVT01007756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11987:13773"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85281.1"
                     /translation="CQHSYVTPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          114 c          105 g           99 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtagg acaagtcaga
      181 acgttaacaa ctatttacat tggtatcagc agaaaccagg gaaagcccct aggctcctga
      241 tctatgctgc gtccaatttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactttcacc atcaccagcc tgcaacctga agatgttgca acttattact
      361 gtcagcatag ttatgttacc ccgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007757             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:16938:7544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007757
VERSION     KCVT01007757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16938:7544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85282.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagttta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcaaca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007758             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:14450:16985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007758
VERSION     KCVT01007758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14450:16985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85283.1"
                     /translation="CLQFKTFPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          117 c          104 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctaagc tcctcatcta
      241 tgctgcatcc actttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtttaaa actttcccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007759             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:7550:12491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007759
VERSION     KCVT01007759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:7550:12491"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85284.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc aggaccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007760             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:19066:13483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007760
VERSION     KCVT01007760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19066:13483"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85285.1"
                     /translation="CMQALEFPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          119 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcaacagagt ggaggctgag
      361 gatgttgggt tttattattg catgcaagct ctagagtttc ctcccacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007761             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:26790:12505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007761
VERSION     KCVT01007761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26790:12505"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85286.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          121 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gaatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007762             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:16968:20252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007762
VERSION     KCVT01007762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16968:20252"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..461
                     /note="immunoglobulin light chain variable region"
     V_region        128..461
     V_segment       128..423
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <401..>433
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85287.1"
                     /translation="CLQSKNSPWTF"
     J_segment       424..461
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        462..>464
                     /gene="IGKC"
BASE COUNT          110 a          123 c          124 g          107 t
ORIGIN      
        1 acatggggat ccttaaaggc agcttgtcag gggccctgag gagcagcctc tagttcagct
       61 ctcagaaatg gggtcctggg ctcctttcct gtggatcctc ctgctctgtg ctccaggctg
      121 caatggggac attgtgctga cccagtctcc agcctctttg gccgtgtctc cagggcagag
      181 ggccaccatc gtctgcagag ccagtgagag tgtcaatgtc tttggaataa acctcattca
      241 ctggtatcag cagaaaccag gacaacctcc taaacccctg atttaccaag catccaataa
      301 agaaactggg gtcccagcca ggttcagcgg cagtgggtct gggaccgatt tcaccctcac
      361 aattaatcct gtggaagctg acgatgctgc agattattac tgtctgcaga gtaagaattc
      421 tccgtggacg tttggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007763             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:17068:9140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007763
VERSION     KCVT01007763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17068:9140"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85288.1"
                     /translation="CQQYNTLPYTF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          107 a          113 c          104 g           97 t
ORIGIN      
        1 acatgggggc agacccagtc aggacacagc atggacatga gggtccccgc tcagctcctg
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgacg ttcagatgac ccagtctcca
      121 tcctacctgt ctgcttctgt aggagacaga gtcaccatca cttgccgggc aagtcaggac
      181 attaacgttt atttaaattg gtatcaccag aaaccgggga aagcccctaa cctcctgatc
      241 tattatgcaa accgtttgga aaatggggtc ccgtcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg caacctgaag attttgcgac ttattactgt
      361 caacagtata atactttacc gtacactttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007764             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:23405:4922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007764
VERSION     KCVT01007764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23405:4922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85289.1"
                     /translation="CQQYDSFPLTF"
     J_segment       384..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT           99 a          114 c          109 g          100 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg tgggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagtagg tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattttgca aatcgtttgg gaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcaacagcct gcaacctgag gattttgcga cttattattg
      361 tcagcagtat gatagtttcc ccctcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01007765             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12467:17854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007765
VERSION     KCVT01007765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12467:17854"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85290.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          122 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacacagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007766             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:26714:8334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007766
VERSION     KCVT01007766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:26714:8334"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85291.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           95 a          123 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctggagtc ccagacaggt
      301 tcattggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01007767             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:11361:13258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007767
VERSION     KCVT01007767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11361:13258"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85292.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          125 c          113 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gtatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007768             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19037:17024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007768
VERSION     KCVT01007768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19037:17024"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85293.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           95 t
ORIGIN      
        1 atgggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtt tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007769             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:28248:11878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007769
VERSION     KCVT01007769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:28248:11878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85294.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          123 c          116 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcaaaaacc tgggcgggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007770             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:24778:9332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007770
VERSION     KCVT01007770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24778:9332"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..383
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85295.1"
                     /translation="CQQHNSYPRTF"
     J_segment       385..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          105 a          118 c          109 g           91 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggta ccagatgtga catccagatg acccagtctc
      121 catcttcctt gtctgcatct gtaggagaca gagtcaccat cacttgccaa gccagtcagg
      181 gtattggcaa ctggttagcc tggtatcggc agaaaccagg gaaagcccct aagctcctga
      241 tctatgctgc atccagttta caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaact cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcagcagca taatagttat cctcggacgt tcggccaagg gaccaaggtg gaaatcaagc
      421 gag
//
LOCUS       KCVT01007771             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:27960:8472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007771
VERSION     KCVT01007771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27960:8472"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85296.1"
                     /translation="CQHSHGTPLTF"
     J_segment       381..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          118 c          105 g           95 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgccc gatgtgacat ccagatgacc cagtctccat
      121 tctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtgagaacg
      181 ttaacgacta tttacattgg tatcagcaga aaccagggaa agcccctaca ctcctgatct
      241 atgctgcttc cactttgaaa agtggggtcc catcaaggtt cagcggcagt ggctctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 aacatagtca tggaacccct ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007772             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8773:14614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007772
VERSION     KCVT01007772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8773:14614"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85297.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca acaaaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccagca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagac ttcactctca ccatcaccag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007773             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:16490:6011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007773
VERSION     KCVT01007773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16490:6011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85298.1"
                     /translation="CQQGVSFPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          113 c          111 g           98 t
ORIGIN      
        1 acatggggat gagcaaaact gacaagtcaa ggcaggaaga tgttgtctcc atcacaactc
       61 attgggtttc tgctgctctg ggttccagcc tccaagggtg aaattgtgct gactcagtct
      121 ccagcctttc ggtctgtgac tctaaaggaa agagtcacca tcacctgcca ggccagtcag
      181 agcattggta ctgccttaca ctggtaccag cagaaaccgg atcagtctcc aaagctcctc
      241 atcacgtatg cttcccagtc catctcaggg gtcccctcaa ggttcagtgg cggtggatct
      301 gggacagagt tcaccctcac catcaatagc ctggaagctg aagatgctgc gacgtattac
      361 tgtcagcagg gtgttagttt cccgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007774             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18842:7089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007774
VERSION     KCVT01007774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18842:7089"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85299.1"
                     /translation="CQQGNSNPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          107 a          111 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccac atgtgacatt cagatgtccc agtttccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggccat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatata
      241 ctatggaaaa agtttggcaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagggtaat agtaatcctc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007775             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8582:2971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007775
VERSION     KCVT01007775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8582:2971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..277
                     /note="immunoglobulin light chain variable region"
     V_region        9..277
     V_segment       9..235
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85300.1"
                     /translation="CQQYDSDSLTF"
     J_segment       240..277
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           73 a           68 c           75 g           64 t
ORIGIN      
        1 acatggggag tcaccatcac ttgtcgggcg actcaggaca ttcgcagtta tttagcgtgg
       61 tatcagcaga aaccagggaa agccccgagg cccttgatct attacgcgtc cactttggaa
      121 agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc
      181 agcagcctgc agcctgaaga ttttgcaact tattactgtc aacaatatga cagtgattcg
      241 ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007776             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9713:12226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007776
VERSION     KCVT01007776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9713:12226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..383
                     /note="immunoglobulin light chain variable region"
     V_region        110..383
     V_segment       110..345
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85301.1"
                     /translation="CQQYNSFPFTF"
     J_segment       352..383
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           97 a          101 c           99 g           89 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagctgtga cattcagatg acccagtctc
      121 catcacttgc cgggcaagtc agggcattta cagttactta aattggtatc agcagaaacc
      181 ggggagagcc cctaaactcc tgatctatta tacaaaccgt ttggaaagtg gggtcccatc
      241 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagcg gcctgcaacc
      301 tgaggatttt gcaacttatt actgtcaaca gtataatagt tttccgttca cttttggcca
      361 ggggaccaaa gtggagatca aacgag
//
LOCUS       KCVT01007777             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19628:9164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007777
VERSION     KCVT01007777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19628:9164"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85302.1"
                     /translation="CGQGTHLPLTF"
     J_segment       393..430
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          121 c          121 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcccgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgctgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtatatagca ctggaaacac atacttgagt tggtatcaac agaagccagg ccaacctccg
      241 aggcgcctaa tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt ccgctcactt tcggcggagg gaccaaggtg
      421 gagatcaaac gag
//
LOCUS       KCVT01007778             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18150:14181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007778
VERSION     KCVT01007778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18150:14181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..403
                     /note="immunoglobulin light chain variable region"
     V_region        101..403
     V_segment       101..384
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85303.1"
                     /translation="CQKYSSSPFTF"
     J_segment       385..403
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           86 a          120 c          107 g           90 t
ORIGIN      
        1 acatggggga gagctgctca gttaggaccc agagagaacc atggaaatcc cagctcagct
       61 tctcttcctc ctgctactgt ggctcccagg taccaccgga caagttattt tgactcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcagcttag cctggtacca gcagaaacct gggcaggccc ccagactcct
      241 cgtctatggt gcatccagga gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagattttg cagtgtatta
      361 ctgtcagaag tatagtagtt ccccattcac tttcggcccc ggg
//
LOCUS       KCVT01007779             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:22267:16857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007779
VERSION     KCVT01007779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22267:16857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..382
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85304.1"
                     /translation="CQQVYSNPAF"
     J_segment       385..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          111 c          109 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtccct gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga tatccaggtg acccagtctc
      121 catctgcctt gtctgcatct gtaggagaca gagtcaccat ctcttgccgg gcaagtcaga
      181 acatttatag gaatttagcg tggtatcagc agagaccagg gaaagcccct aagctcctga
      241 tctatgctgc atccagattg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcaacc tacagcctga agattctgca atttattact
      361 gtcaacaggt ttatagtaac ccggcgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01007780             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14985:19105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007780
VERSION     KCVT01007780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14985:19105"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85305.1"
                     /translation="CMQALEFPLTF"
     J_segment       407..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaata cctatttgga atggcaccgg cagatgccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctgacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007781             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:19298:4759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007781
VERSION     KCVT01007781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19298:4759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85306.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          122 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccctggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgaa gatggaaaca cctatttgga ttggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007782             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:19029:12726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007782
VERSION     KCVT01007782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19029:12726"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85307.1"
                     /translation="CLQSKNSPWSF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          100 a          116 c          115 g           99 t
ORIGIN      
        1 acatgggagc agcctctagt tcagctctca gaaatggggt cctgggctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggctgcagt ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accatcacct gcagagccag tgagagtgtc
      181 agtgcctttg gaataagcct cattcactgg tatcaacaga aaccaggaca acctcctaaa
      241 ctcctgattt accaagcaat caataaggag actggggtcc cagccaggtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aacctgacga tggtgcagat
      361 tattactgtc tgcagagtaa gaattctccg tggtcgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01007783             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9332:7122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007783
VERSION     KCVT01007783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9332:7122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85308.1"
                     /translation="CQQHNTYPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          107 a          118 c          108 g           93 t
ORIGIN      
        1 acatgggggg gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaaacccc
      241 tgatctttta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataatact tacccgtaca cttttggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007784             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13528:4236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007784
VERSION     KCVT01007784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13528:4236"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85309.1"
                     /translation="CQQYNNSPYSF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          109 c          109 g           98 t
ORIGIN      
        1 acatgggggg agtcagtccc attcaggaca cagcatggac atgagggtcc ccctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcgagtcag
      181 gacattgaca gttatttgag ttggtatcag cagaaaccag ggaaagcccc taagcccctg
      241 atctattata catccagttt gcaaagaggg gtaccgtcaa ggttcagtgg aagtcgatct
      301 gggacagatt atagtctcac catcagcagt ctgcagcctg aagattttgc tacatattac
      361 tgtcaacagt ataataattc cccgtacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007785             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:20911:14412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007785
VERSION     KCVT01007785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20911:14412"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85310.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aagtctagtc
      181 agagcctctt ggatagtggg gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007786             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11278:6020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007786
VERSION     KCVT01007786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11278:6020"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..405
                     /note="immunoglobulin light chain variable region"
     V_region        85..405
     V_segment       85..367
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85311.1"
                     /translation="CQQYSDFLLTF"
     J_segment       368..405
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>408
                     /gene="IGKC"
BASE COUNT           91 a          123 c          106 g           88 t
ORIGIN      
        1 acatggggga cccagaggga accatggaag ccccagcaca gcttctcttc ctcctgctgc
       61 tctggatccc agataccgcc ggaaaaattg tcatgacgca gtctccagcc accctgtctt
      121 tgtctccagg ggaaacagcc accctctcct gcagggccag tgagagtgtt ggcaccttct
      181 tagcctggta ccaacagaaa cctgggcagg ctcccaagct ccttgtccat agtgctttct
      241 tcagggcccc tggcatccca gacaggttca gtggcagcgg gtctaggaca gagttcactc
      301 tcaccatcaa caccctggag cctgaagatg ttggagttta tcactgtcag cagtatagtg
      361 acttcctgct cactttcggc ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01007787             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17133:6525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007787
VERSION     KCVT01007787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17133:6525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85312.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          119 g          104 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacac ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007788             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12023:16143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007788
VERSION     KCVT01007788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12023:16143"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85313.1"
                     /translation="CMQSIKDPFTF"
     J_segment       394..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          100 a          120 c          109 g          105 t
ORIGIN      
        1 acatggggag gactcctcag ttcatcttct cacgatgaga ctccctgctc agctcctcgg
       61 gctgttgatg ctctgggtcc ctggatccag tggggatatt gtgatgaccc agaccccact
      121 ctcggtgccc gtcacccctg gagagccggc ctccatctcc tgcaggtcta gtcaaagcct
      181 tctccatagt aatggagaca cctatttaca ttggtacctt cagaggtcag gccagtctcc
      241 acggctcctg atctataaag taaccaatcg gctacctggg gtcccagaca ggttcagtgg
      301 cagtgggtca ggcacagatt tcacactgaa aatcagcagg gtggagcctg aggatattgg
      361 tgtttatttc tgcatgcaaa gtataaaaga tccattcact ttcggccccg ggaccaaact
      421 ggatatcaaa cgag
//
LOCUS       KCVT01007789             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15718:14574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007789
VERSION     KCVT01007789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15718:14574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85314.1"
                     /translation="CQQHDDSPRTF"
     J_segment       389..424
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          111 a          116 c          112 g           88 t
ORIGIN      
        1 acatggggga ggagtcagtc tcagacagga cacagcatgg acacgagggt ccccgctcag
       61 ctcctggggc tcctgttgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtca ccatcacttg cagagccagt
      181 caggatatta acaactggtt ggcctggtat caacagaaac cagggaaagc ccctaaggtc
      241 ctgatctata gggcatccat tttggaaaca ggggtcccat caaggttcag tggaagtgga
      301 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagatat cgcaacatat
      361 tactgtcaac agcatgatga ttcccctcgg acgttcggcc aagggaccaa ggtggaaatc
      421 aaacgag
//
LOCUS       KCVT01007790             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:3851:19141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007790
VERSION     KCVT01007790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:3851:19141"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85315.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          122 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttaagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007791             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:16302:4479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007791
VERSION     KCVT01007791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16302:4479"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85316.1"
                     /translation="CQQYNSLPLTF"
     J_segment       385..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          111 c          108 g          100 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gtcagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtgggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagca gttttttaaa ttggtatcag cagaaaccgg ggaaagcccc taatctcctg
      241 atctattatg caaaccgttt ggaaactggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt acctctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007792             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12947:10674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007792
VERSION     KCVT01007792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12947:10674"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..393
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85317.1"
                     /translation="CLQSKNSPWTF"
     J_segment       394..431
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT          104 a          115 c          115 g          100 t
ORIGIN      
        1 acatggggag gagcagcctc tagttcagct ctcagaaatg gggtcctggg ctcctttcct
       61 gtggatcctc ctgctctgtg ctccaggctg caatggggac attgtgctga cccagtctcc
      121 agcctctttg gccgtgtctc cagggcagag ggccaccatc gtctgcagag ccagtgagag
      181 tgtcaatgtc tttggaataa acctcattca ctggtatcag cagaaaccag gacaacctcc
      241 taaacccctg atttaccaag catccaataa agaaactggg gtcccagcca ggttcagcgg
      301 cagtgggtct gggaccgatt tcaccctcac aattaatcct gtggaagctg acgatgctgc
      361 agattattac tgtctgcaga gtaagaattc tccgtggacg tttggccaag ggaccaaggt
      421 ggaaatcaaa cgag
//
LOCUS       KCVT01007793             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10124:22896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007793
VERSION     KCVT01007793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10124:22896"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85318.1"
                     /translation="CQQYDSDPRTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          117 c          113 g           92 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaattgtga catccagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccgctatg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgcgcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007794             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:24578:6504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007794
VERSION     KCVT01007794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24578:6504"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85319.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agttagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007795             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:12385:4889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007795
VERSION     KCVT01007795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12385:4889"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85320.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT          100 a          120 c          118 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcagc agagaccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctaaccgg gactctgggg tcccagacag atttaccggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01007796             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:20008:14930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007796
VERSION     KCVT01007796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20008:14930"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..408
                     /note="immunoglobulin light chain variable region"
     V_region        125..408
     V_segment       125..370
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <348..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85321.1"
                     /translation="CMQAREFPFTF"
     J_segment       371..408
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>411
                     /gene="IGKC"
BASE COUNT           95 a          112 c          108 g           96 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccat ctcctgcagg tctagtcaga gcctcttcga tagtgaggag gggaacacct
      181 atttggaatg gtacctacag aagccaggcc agtctccaca actcttgatt tatgaggtct
      241 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      301 cactgaaaat cagcagagtg gaggctgagg atgctggggt ttattactgc atgcaagctc
      361 gagagtttcc attcactttc ggccccggga ccaaactgga catcaaacga g
//
LOCUS       KCVT01007797             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:20977:2178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007797
VERSION     KCVT01007797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20977:2178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85322.1"
                     /translation="CMQALEFPFIF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          113 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc attcattttc ggcccctgga
      421 ccacactgga tatcaaacga g
//
LOCUS       KCVT01007798             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:22525:20086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007798
VERSION     KCVT01007798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22525:20086"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85323.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          108 c          109 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt gagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007799             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:20964:13870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007799
VERSION     KCVT01007799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20964:13870"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85324.1"
                     /translation="CMQAREFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          118 c          123 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc actcttggag agccggcctc catctcctgc atgtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatgtgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctcgagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007800             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:7095:20929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007800
VERSION     KCVT01007800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7095:20929"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..402
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85325.1"
                     /translation="CQQYDSDSLTF"
     J_segment       407..444
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>447
                     /gene="IGKC"
BASE COUNT          108 a          123 c          118 g           98 t
ORIGIN      
        1 acatggggga ggctaggcac gcttcatgca ggagtcagac ccagtcagga cacagcatgg
       61 acatgagggt ccccgctcag ctcctaggac tcctgctgct ctgtctccca ggtgccaaat
      121 gtgacatcca gatgacccag tctccatcct ccctgtctgc atctgtagga gacagagtca
      181 ccatcacttg tcgggcgact caggacattc gcacttattt agcgtggtat cagcagaaac
      241 cagggaaagc cccgaagccc ttgatctatt acgcgtccac tttggaaggt ggggtcccat
      301 caaggttcag cggcagtgga tctgggacag aattcactct caccatcagc agcctgcagc
      361 ctgaagattt tgcaacttat tactgtcaac agtatgacag tgattcgctc actttcggtg
      421 gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01007801             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9704:8814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007801
VERSION     KCVT01007801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9704:8814"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..430
                     /note="immunoglobulin light chain variable region"
     V_region        96..430
     V_segment       96..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85326.1"
                     /translation="CGQGTHLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           95 a          125 c          118 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt gggggtgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gtaggtctag tcaaagcctt
      181 gtccacacca ctggaaacac atacttgagt tggtatcagc agaagccagg ccaacctcca
      241 aggcgcctac tttatgaggt ttcttaccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacacctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01007802             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21969:9120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007802
VERSION     KCVT01007802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21969:9120"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85327.1"
                     /translation="CQQYDSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          116 c          107 g           98 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtgg gagacagagt caccatcact tgccgggcta gtcaggacat
      181 tagtaatttt ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatggaaac cgtttgggaa gcggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcgactt atcattgtca
      361 gcagtatgat agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007803             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:24453:6979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007803
VERSION     KCVT01007803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24453:6979"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85328.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctagagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007804             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13245:6493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007804
VERSION     KCVT01007804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13245:6493"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..378
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85329.1"
                     /translation="CQQSYRYPLTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT          100 a          117 c          109 g           98 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccaggtgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgag
      181 aacgttaaca actatttaca ttggtatcag cagaagccag ggaaagcccc taaactcctg
      241 atgtttctta catccacttt gcagagtggc gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcgc catcagcagc ctgcagcctg aagatgctgc aacttattac
      361 tgtcagcaga gttatcgtta tccgctcact ttcggtggag ggacccaggt ggaaatcaat
      421 cgag
//
LOCUS       KCVT01007805             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7538:6508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007805
VERSION     KCVT01007805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7538:6508"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85330.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          120 c          108 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007806             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:7677:19878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007806
VERSION     KCVT01007806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7677:19878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85331.1"
                     /translation="CQQYNSYPLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          119 c          108 g           96 t
ORIGIN      
        1 acatgggggc aggaatcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg catctgtggg agacacagtc accatcactt gtcgggcaag
      181 tcagggcatt agcagttatt tagcctggta tcagcagaaa ccagggaaag cccctaagcg
      241 cctgatctat gctgcatcca ctttacaaag tggggtccca tcaagcttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctacag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtataata gttatccgct cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01007807             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:24162:14316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007807
VERSION     KCVT01007807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24162:14316"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85332.1"
                     /translation="CMQPLEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          123 c          120 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtgc tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctcc agaagccagg
      241 ccagtctcca catctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaacc tctagagttt ccgtggacgt tcggccaggg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007808             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:21176:5276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007808
VERSION     KCVT01007808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21176:5276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85333.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          122 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatggggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007809             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:16885:14154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007809
VERSION     KCVT01007809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16885:14154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85334.1"
                     /translation="CVQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          121 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgact tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc gttcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007810             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:6790:10931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007810
VERSION     KCVT01007810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6790:10931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85335.1"
                     /translation="CQQYNSLPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          111 a          109 c          108 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtta ttatttaaat tggtatcaac agaaaccggg gaaagcccct aaggtcctga
      241 tctattacac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca agttattact
      361 gtcaacaata taatagttta ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007811             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:13506:5756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007811
VERSION     KCVT01007811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13506:5756"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85336.1"
                     /translation="CQQNSNWPLTF"
     J_segment       379..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          101 a          122 c          111 g           84 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ccccagcaca gcttctcttc
       61 ctcctgctgc tctggctccc agataccacc ggagaaatag tgatgacgca gtctccagcc
      121 accctgtctt tgtctccagg agaaagagcc accctctcct gcagggccag tcagagtgtc
      181 agcagcagcg tagcctggta ccagcaaaaa cctgggcagg ctcccagact cctcatctat
      241 ggtgcatcca acagggccac tggcatccca gacagattca gtggcagtgg gtctgggaca
      301 gagttcactc tcaccatcag cagcctggag cctgaagatg ttgcacttta ttattgtcag
      361 cagaatagta actggcctct cactttcggt ggagggacca aggtggagat caaacgag
//
LOCUS       KCVT01007812             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:22756:4485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007812
VERSION     KCVT01007812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22756:4485"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85337.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          118 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgcactgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007813             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:23320:13891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007813
VERSION     KCVT01007813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23320:13891"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..362
                     /note="immunoglobulin light chain variable region"
     V_region        82..362
     V_segment       82..322
                     /gene="IGKV1-46"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85338.1"
                     /translation="CQPFKSYLSVPF"
     J_segment       330..362
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>365
                     /gene="IGKC"
BASE COUNT           97 a           88 c           91 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacaggat ggacatgacg gtccccgctt atctcctggg
       61 gctccttctg ctctggctcc caggagacaa agtcaccatc acttgcaggg caagtcagga
      121 cattggtaat tatttaaatt ggtatcagca gaaaccagga aaagctccta aggtcctgat
      181 ctatggtgta tccaatttac aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      241 gacagatctt actctcacca tcagcagctt gcagcctgaa gattttgcaa cttattattg
      301 tcaaccgttt aaaagttacc tttcggtccc tttcggcgga gggaccaagg tggagatcaa
      361 acgag
//
LOCUS       KCVT01007814             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13395:14410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007814
VERSION     KCVT01007814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13395:14410"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85339.1"
                     /translation="CMQSLEIPPTF"
     J_segment       405..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           93 a          122 c          122 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgggga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccacccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggcg tttattactg catgcaatct ctagagattc ctcccacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007815             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:20160:12892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007815
VERSION     KCVT01007815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20160:12892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85340.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          121 c          117 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgt agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007816             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:8302:9429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007816
VERSION     KCVT01007816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8302:9429"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..392
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85341.1"
                     /translation="CGQGTHLPWTF"
     J_segment       393..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g           95 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatctcct gcaggtctag tcaaagcctt
      181 gtacacatca atggcaacac atacttgagt tggtatcagc agagcccagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctatccgg gacgctgggg tcccagacag attcagtggc
      301 agtggggcag ggacagattt cacactgaaa atcagcagag tggaggctga ggatgttggg
      361 ctttattact gcgggcaagg tacacacctt ccgtggacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01007817             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19433:3754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007817
VERSION     KCVT01007817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19433:3754"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85342.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          118 c          125 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc accctgggag agccggcctc catgtcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggcacctg cagaggccag
      241 gccagtctcc acagctcttg atttatgagg tttcctatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007818             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14098:19616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007818
VERSION     KCVT01007818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14098:19616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85343.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          103 a          126 c          120 g           88 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcaaaaac ctgggcaggc
      241 tcccagactc ctcctctatg gtgcatccaa cagggccact ggcttcccag acaggttcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007819             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:20229:19213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007819
VERSION     KCVT01007819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20229:19213"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85344.1"
                     /translation="CQQHDNSPPTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          116 c          109 g           93 t
ORIGIN      
        1 acatggggtc agtctcagac agggcacagc atggacacga gggtccccgc tcagctcctg
       61 gggctcctgt tgctctggct cccaggtgcc agatgtgaca tccagatgac ccagtctcct
      121 tcctccctgt ctgcatctat aggcgacaga gtcaccatca cttgcagagc cagtcagggt
      181 attagcgact ggttggcctg gtatcaacag aaaccaggga aagcccctaa actcctgatc
      241 tatagggcat ccaatttgga aacaggggtc ccatcaaggt tcagtggaag tggatctggg
      301 acagatttca ctctcaccat cagcagcctg caggctgaag atttcgcaac atatttctgt
      361 caacagcatg ataattcccc tcccactttc ggtggaggga ctaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007820             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:5408:12355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007820
VERSION     KCVT01007820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5408:12355"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..357
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85345.1"
                     /translation="SMHDYGWPTTF"
     J_segment       383..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          115 c          115 g           92 t
ORIGIN      
        1 acatggggag gctctgagca ccgcctgcca gcatgttctt gggagttcag gtgcagctcc
       61 tctggagcct ggctttctgg agggcagtga gtggagacat catcctgaac cagacgccag
      121 catccctgac tgcacctcca ggagagacag tgtccatctc ctgccaagcc agaccagatg
      181 tacatggtga aataccttgg atccggataa accttgaaca aagacttgaa ccccttttat
      241 ctcatgtcac taccttggcc ccaggtgtcg cagcccggtt catcaccaag gggagtggca
      301 ccagttatgt tttcagcatc agtgacctgc agcctgggga ctctggggac tattactcca
      361 tgcatgacta tgggtggcca accactttcg gtggagggac caaggtggag atcaaacgaa
//
LOCUS       KCVT01007821             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:15717:16107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007821
VERSION     KCVT01007821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15717:16107"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85346.1"
                     /translation="CQQYDSDPHTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          117 c          112 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcacac tttcggtgga gggaccaagg tagagatcaa
      421 acgag
//
LOCUS       KCVT01007822             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:2699:9780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007822
VERSION     KCVT01007822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:2699:9780"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..378
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85347.1"
                     /translation="CQQDFDWPPTF"
     J_segment       381..415
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           96 a          125 c          110 g           87 t
ORIGIN      
        1 acatgggggc tcagttagga cccagaggga accatggaag ctccagcaca gcttctcttc
       61 ctcctgctac tctggatccc agataccacc ggagaagttg tgatgacgca gtctccagcc
      121 accctgtctt tgtctccagg ggaaagagcc accctctcct gcagggccag tcagagtgtt
      181 ggcaacacct taacctggta ccagcacaaa cctgggcagg ctcccaagct cctcctctat
      241 ggtgcatcca ccagggcctc cggcatccca ggcaggttca gtgccagtgg gtctggaaca
      301 gagtttactc tcaccatcag cagcctggag cctgaagatg ttggaattta ttactgtcag
      361 caggattttg actggcctcc gacgttcggc caagggacca aggtggaaat caaacgag
//
LOCUS       KCVT01007823             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:24400:12999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007823
VERSION     KCVT01007823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24400:12999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85348.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          100 a          119 c          117 g           94 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgactcagtc tccactctcc
      121 ctgtccatca cccctggaca gccggcctcc atctcctaca ggtctagtca aagccttgta
      181 cacatcaatg gaaacacata cttgagttgg tatcagcaga acccaggcca acctccaagg
      241 cgcctaattt atgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttgggctt
      361 tattactgcg ggcaaggtac acaccttccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01007824             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:11246:10285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007824
VERSION     KCVT01007824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11246:10285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85349.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          120 c          122 g          104 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgag gatggaaaca cttacttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007825             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14517:18670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007825
VERSION     KCVT01007825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14517:18670"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85350.1"
                     /translation="CQQDFDWPPTF"
     J_segment       393..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cattcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007826             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13187:21759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007826
VERSION     KCVT01007826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13187:21759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..398
                     /note="immunoglobulin light chain variable region"
     V_region        101..398
     V_segment       101..360
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <338..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85351.1"
                     /translation="CLQFKTYPNSF"
     J_segment       363..398
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>401
                     /gene="IGKC"
BASE COUNT           95 a          111 c           99 g           96 t
ORIGIN      
        1 acatgggggg agtcagacac agtcaggaca cagcatggac atgagggccc ccgctcatct
       61 cctagggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgactcagtc
      121 tccatcttcc ctgtctgcat ctgtaggaga cactgtcacc atctcttgcc gggcaagtca
      181 gggtattagc agttctttaa gttggtttca gcagaaacca gggaaagccc ctcagctcct
      241 catctatgct gcatcaaggt tcagcggcag tggatctggg acagaattct ctctcaccat
      301 caccagcctg cagcctgaag attttgcaac ttatttctgt ctgcagttta aaacttaccc
      361 gaacagtttt ggccagggga ccaaagtgga gatcaaacga g
//
LOCUS       KCVT01007827             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:23789:9431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007827
VERSION     KCVT01007827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23789:9431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..434
                     /note="immunoglobulin light chain variable region"
     V_region        95..434
     V_segment       95..396
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85352.1"
                     /translation="CMQALEFPLTF"
     J_segment       397..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT           98 a          120 c          117 g          102 t
ORIGIN      
        1 acatggggac gactcctcag gtcaccttct cacaatgagg ctccctgctc agctcctggg
       61 actgctaatg ctctggctcc ctggatccag tggggacatt gtgatgaccc agactccact
      121 ctccctgccc gtcacccttg gagagccggc ctccatctcc tgcaggtcta gtcagaacct
      181 cctggatagt gaggatggaa acacctattt gcactggtac ctgaagaagc caggccagtc
      241 tccacagctc ttaatttatg aagtttccaa ccgggcctct ggagtcccag acaggttcag
      301 tggcagtggg tcagacactg atttcacact gaaaatcagc agagtggagg ctgaggatgt
      361 tggggtttat tactgcatgc aagctctaga gtttccgctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007828             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:4807:8248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007828
VERSION     KCVT01007828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4807:8248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85353.1"
                     /translation="CQQYSDFLLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           96 a          125 c          113 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggatcccag ataccgccgg agaaattgtc atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaacagccac cctctcctgc agggccagtg
      181 agagtgttgg caccttctta gcctggtacc aacagaaacc tgggcaggct cccaaactcc
      241 ttgtccatag tgcattcttc agggcccctg gcatcccaga caggttcagt ggcagcgggt
      301 ctgggacaga gttcactctc accatcaaca ccctggagcc tgaagatgtt ggagtttatc
      361 actgtcagca gtatagtgac ttcctgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007829             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18988:17855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007829
VERSION     KCVT01007829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18988:17855"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85354.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag attcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acctattact
      361 gtcaacagta tgacagtgat ccgttcactt tcggtggggg gaccaaggta gacatcaaac
      421 gag
//
LOCUS       KCVT01007830             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:14783:20404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007830
VERSION     KCVT01007830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14783:20404"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85355.1"
                     /translation="CQQYDSLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          101 a          113 c          110 g          100 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccgtcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagca attttttagt ttggtatcga cagaaaccgg ggaaatcccc taacctcctg
      241 atctattatg caaaccgttt ggaaagtggg gtcccttcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt atgatagttt accgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007831             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:4973:6728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007831
VERSION     KCVT01007831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4973:6728"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..364
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85356.1"
                     /translation="CQQYDKSPPTF"
     J_segment       367..401
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          103 a          112 c          109 g           80 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agggtcacca tcacttgcag agccagtcag ggtatcagca actggttggc
      181 ctggtatcaa cagaaaccag ggagagcccc taacctcctg atgtataggg cgtccaattt
      241 gcaaggaggg gtcccatcaa ggttcagagg aagtggatct gggacagatt tcactctcac
      301 catcagcagc ctgcagcctg aggatgtcgc tacatattac tgtcaacagt atgataagtc
      361 ccctccgacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007832             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:24324:11171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007832
VERSION     KCVT01007832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24324:11171"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85357.1"
                     /translation="CMQALEFPCTF"
     J_segment       408..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           96 a          121 c          122 g          105 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga ctggtacctg cagaagccgg
      241 gccagtctcc acagctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gactctgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtgtacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007833             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:24092:12920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007833
VERSION     KCVT01007833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24092:12920"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..234
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <211..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85358.1"
                     /translation="CMQSLEFPLTF"
     J_segment       235..271
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>274
                     /gene="IGKC"
BASE COUNT           68 a           56 c           82 g           68 t
ORIGIN      
        1 acatggggtc agagcctctt ggatagtgag gatggaaaca cttatttgga atggtacctg
       61 cagaagccag gccagtctct agagctcttg atttatgagg tttccaaccg ggcctctgga
      121 gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga
      181 gtggaggctg aggatgttgg ggtttattac tgcatgcaat ctctagagtt tcctctcact
      241 ttcggcggag ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007834             263 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16712:3279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007834
VERSION     KCVT01007834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 263)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16712:3279"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..260
                     /note="immunoglobulin light chain variable region"
     V_region        28..260
     V_segment       28..222
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <200..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85359.1"
                     /translation="CMQALEFPLTF"
     J_segment       223..260
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>263
                     /gene="IGKC"
BASE COUNT           62 a           61 c           77 g           63 t
ORIGIN      
        1 atggggactg atcacgactc ctcaggtcac ctatttggat tggtacctgc agaagccagg
       61 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      121 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      181 ggatgttggg gtttattact gcatgcaagc tctagagttt ccgctcactt tcggcggagg
      241 gaccaaggtg gagatcaaac gag
//
LOCUS       KCVT01007835             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:23135:8471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007835
VERSION     KCVT01007835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23135:8471"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85360.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          118 c          115 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg cgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtctcc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007836             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:9974:17346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007836
VERSION     KCVT01007836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9974:17346"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85361.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          112 g           91 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007837             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:13150:4413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007837
VERSION     KCVT01007837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13150:4413"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85362.1"
                     /translation="CQQGDSYPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          112 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcatctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg tcccagtctc
      121 cttcctccct gtctgcatct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagaga ttatttaaat tggtatcagc agcaaccggg gaaagcccct aaactcctga
      241 tgtattatgc aaacagtctg gcaagtggag tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaggg tgacagttat cctcggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007838             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:19318:10352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007838
VERSION     KCVT01007838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19318:10352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..374
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85363.1"
                     /translation="CQQGYTYLYSF"
     J_segment       382..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          104 a          116 c          105 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctga
      241 tctatagggc atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatacttac ctgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007839             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:28979:15934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007839
VERSION     KCVT01007839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:28979:15934"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85364.1"
                     /translation="CMQALQFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgtt aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca cctcttgatt tatgagtttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca ctctgaatat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tacaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007840             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:7249:14963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007840
VERSION     KCVT01007840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7249:14963"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..371
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85365.1"
                     /translation="CQQHDNMPLTF"
     J_segment       377..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          105 a          112 c          113 g           87 t
ORIGIN      
        1 atggggagtc tcagacagga cacagcatgg acacgagggt ccccgctcag ctcctggggc
       61 tcctgttgct ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatcct
      121 ccctgtctgc atctgtggga gacagagtca ccatcacttg cagggccagt cagggtatta
      181 gcaactggtt ggcctggtat caacagaaac cagggaaagc ccctaagctc ctgatctata
      241 gggcatggaa tttggaaaca ggggtcccat caaggttcag tggaagtgga tccgggacag
      301 atttcactct caccatcagc agcctgcagc ctgaagatat cgcaacatat tactgtcaac
      361 agcatgataa tatgccgctc actttcggtg gagggaccaa ggtggacatc aaacgag
//
LOCUS       KCVT01007841             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7898:7752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007841
VERSION     KCVT01007841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7898:7752"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85366.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          122 c          117 g           86 t
ORIGIN      
        1 acatgggggg gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccaggctcct
      241 catctatggt gcatccaaca gggccactgg catcccagac aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cagtttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007842             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9710:14226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007842
VERSION     KCVT01007842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9710:14226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85367.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007843             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:12051:11579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007843
VERSION     KCVT01007843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12051:11579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85368.1"
                     /translation="CLQYKTYPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          114 c          100 g           99 t
ORIGIN      
        1 acatgggaga cacagtcagg acacagcatg gacatgaggg cccccgctca tctcctaggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgactca gtctccatct
      121 tccctgtctg catctgtagg agacactgtc accatcactt gccgggcaag tcaggatatc
      181 agcaattatt tacattggtt tcagcagaaa ccagggaaag cccctaagct cctgatctat
      241 gctgcatcca gtttggcaag tggtgtccca tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta tttctgtcta
      361 cagtataaaa cttacccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01007844             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:14998:8691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007844
VERSION     KCVT01007844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14998:8691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..365
                     /note="immunoglobulin light chain variable region"
     V_region        44..365
     V_segment       44..327
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85369.1"
                     /translation="CQQYNSDPRTF"
     J_segment       331..365
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>368
                     /gene="IGKC"
BASE COUNT           91 a           98 c           95 g           84 t
ORIGIN      
        1 acatggggga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
       61 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      121 tcagggcatt cgcagttatt tagcgtggta tcaacagaaa ccagggaaag ccccgaagcc
      181 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttta gcggcagtgg
      241 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      301 ttactgtcaa cagtataaca gtgacccgcg cactttcggt ggagggacca aggtggagat
      361 caaacgag
//
LOCUS       KCVT01007845             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:18169:4973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007845
VERSION     KCVT01007845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18169:4973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85370.1"
                     /translation="CQHSYDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          116 c          105 g           97 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgcg
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagcccc tgagctcctg
      241 atttatgtta catccacttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcata gttatgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007846             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11007:6709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007846
VERSION     KCVT01007846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11007:6709"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85371.1"
                     /translation="CQHSYDTPYTF"
     J_segment       386..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           96 t
ORIGIN      
        1 acatgggggg agtcagtctc agtcaggaca cagcatggac atgagggcct ctgctcagct
       61 cctagggctc ctgctgctct ggctcccagg cgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtgggaga cagagtcacc atcacttgca gggcaagtgc
      181 gaacgttaac aactatttac attggtatca gcagaaacca gggaaagtcc ctgagctcct
      241 gatctatgct gcatcgtctt tgcaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcaccctca ccatcagcag cctgcagcct gaagatgttg caacttatta
      361 ctgtcagcat agttatgata ccccctacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007847             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:9314:22862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007847
VERSION     KCVT01007847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:9314:22862"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..376
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85372.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          103 a          117 c          107 g           94 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc atggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc aaatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcatctgt aggagacaga gtcaccatca cttgtcgggc gactcaggac
      181 attcgcagtt atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc
      241 tattacgcgt ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcaccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgattc cctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01007848             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:11583:12795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007848
VERSION     KCVT01007848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11583:12795"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85373.1"
                     /translation="CQQYNSEPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          116 c          112 g           91 t
ORIGIN      
        1 atgggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaacccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgagc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007849             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:20420:14166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007849
VERSION     KCVT01007849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20420:14166"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85374.1"
                     /translation="CQQHDNSPPTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          115 c          109 g           92 t
ORIGIN      
        1 acatggggag tctcagacag ggcacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccttc
      121 ctccctgtct gcatctatag gcgacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcgactgg ttggcctggt atcaacagaa accagggaaa gcccctaaac tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcaaggttc agtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca ggctgaagat ttcgcaacat atttctgtca
      361 acagcatgat aattcccctc ccactttcgg tggagggact aaggtggaga tcaaacgag
//
LOCUS       KCVT01007850             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:19125:23072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007850
VERSION     KCVT01007850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19125:23072"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85375.1"
                     /translation="CQQHDDSPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          116 c          113 g           87 t
ORIGIN      
        1 acatgggggg tcagtctcag acaggacaca gcatggacac gagggtcccc gctcagctcc
       61 tggggctcct gttgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgcaga gccagtcaga
      181 gtattaacga ctggttggcc tggtatcaac agagaccagg gaaggcccct aagctcctga
      241 tctatagggc atccaatttg gaaacagggg tcccatcaag gttcagtgga agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agatatcgca acatattact
      361 gtcaacagca tgatgattcc ccgtggacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007851             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:6984:11181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007851
VERSION     KCVT01007851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6984:11181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85376.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          122 c          120 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgagat gacccagact
      121 ccactctccc tgcccgtcac ccttggagaa ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttgcact ggtacctgca gaagccaggc
      241 cagtctccac agctcttaat ttacgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc cgctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007852             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8722:4310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007852
VERSION     KCVT01007852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8722:4310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..369
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85377.1"
                     /translation="CQQHNGYPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          119 c          107 g           89 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgttg gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 taccaatgat ttagcctggt atcagcagag accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagcataat ggataccctc cgacgttcgg ccaagggacc agggtggaaa tcaaacgag
//
LOCUS       KCVT01007853             531 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7376:9908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007853
VERSION     KCVT01007853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 531)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7376:9908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    195..528
                     /note="immunoglobulin light chain variable region"
     V_region        195..528
     V_segment       195..490
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <468..>500
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85378.1"
                     /translation="CLQTKNSPWTF"
     J_segment       491..528
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        529..>531
                     /gene="IGKC"
BASE COUNT          124 a          141 c          140 g          126 t
ORIGIN      
        1 acatggggga acccaaactt ttctgagctg atttgcatgt tgggtcatta ggcagcagtc
       61 caagctgctt agagcatcct tacaggcagc ttgtcagggg ccctgaggag cagcctctag
      121 ttcagctctc agaaatgggg tcctgggctc ctttcctgtg gatcctcctg ctctgtgctc
      181 caggctgcaa tggggacatt gtgctgaccc agtctccagc ctctttggcc gtgtctccag
      241 ggcagagggc caccatcacc tgcagagcca gtgagagtgt cagtgtcttt ggaataaacc
      301 tcattcactg gtatcagcag aaaccaggac aacctcctaa atccctgatt taccaagcat
      361 ccaataaaga cactggggtc ccagccaggt tcagcggcag tgggtctggg accgatttca
      421 ccctcacaat taatcctgtg gaagctgacg atgctgcaga ttattactgt ctgcagacta
      481 agaattctcc gtggacgttt ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007854             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:15044:10088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007854
VERSION     KCVT01007854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:15044:10088"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..431
                     /note="immunoglobulin light chain variable region"
     V_region        113..431
     V_segment       113..396
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85379.1"
                     /translation="CQQYFSSPFTF"
     J_segment       397..431
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>437
                     /gene="IGKC"
BASE COUNT           99 a          130 c          114 g           94 t
ORIGIN      
        1 acatggggag agctctggag aagagctgct cagttaggac ccagagagaa ccatggaaat
       61 cccagctcag cttctcttcc tcctgctact gtggctccca ggtaccaccg gacaagttat
      121 attgactcag tctccagcca ccctgtcttt gtctccaggg gaaagagcca ccctctcctg
      181 cagggccagt cagagtgttg gcagcagctt agcctggtac cagcagaaac ctgggcaggc
      241 ccccaggctc ctcatctatg gtgcatccag cagggccact ggcatcccag acaggttcag
      301 tggcagaggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagattt
      361 tgcgatgtat tactgtcagc agtattttag ctccccattc actttcggcc ccgggaccaa
      421 actggatatc agacgag
//
LOCUS       KCVT01007855             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19179:16449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007855
VERSION     KCVT01007855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19179:16449"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..404
                     /note="immunoglobulin light chain variable region"
     V_region        99..404
     V_segment       99..367
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85380.1"
                     /translation="CQQNSNWPLTF"
     J_segment       368..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           98 a          117 c          110 g           82 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg ctcccagata ccaccggaga aatagtgatg acgcagtctc
      121 cagacaccct gtctttgtct ccaggagaaa gagccaccct ctcctgcagg gccagtcaga
      181 gtgtcagcag cagcagaaac ctgggcaggc tcccagactc ctcatctatg gtgcatccaa
      241 cagggccact ggcatcccag acaggttcag tggcggtggg tctgggacag agttcactct
      301 caccatcagc agcctggagc ctgaagatgt tgcactttat tattgtcagc agaatagtaa
      361 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01007856             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:15530:10178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007856
VERSION     KCVT01007856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15530:10178"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85381.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          123 c          113 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcgtag cctggtacca gcaaaaacct gggcaggctc ccagactcct
      241 catctatggt gcatccaaca gggccactgg catcccagac agattcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg cactttatta
      361 ttgtcagcag aatagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007857             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:21777:15009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007857
VERSION     KCVT01007857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21777:15009"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85382.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          118 c          122 g          101 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcagcc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacaa ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgagttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007858             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:18360:2905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007858
VERSION     KCVT01007858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18360:2905"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85383.1"
                     /translation="CMQALEFPYTF"
     J_segment       402..437
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagagtc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 ccctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctcctca actcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat caacagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttacactttt ggccagggac
      421 cacagtggag atcaaacgag
//
LOCUS       KCVT01007859             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:14906:12860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007859
VERSION     KCVT01007859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14906:12860"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85384.1"
                     /translation="CQQYNSDTRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          113 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggagattggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattat
      361 tgtcaacagt ataacagtga cacgcgcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007860             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17117:16280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007860
VERSION     KCVT01007860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17117:16280"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..397
                     /gene="IGKV2-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85385.1"
                     /translation="CMQDIQLPLTF"
     J_segment       398..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           89 a          124 c          122 g          103 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct ggtgctctgg ctccctggga ccagtgggga tattgtgatg actcagactc
      121 cactctccct gcccgtcacc cctggggagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgca tagtaatgga tacacctatt tgttttggta cctgcagaag ccaggccagt
      241 ctccacaact cctgatctac ttgggttcca accgggcctc tggagtccca gacaggttca
      301 gtggcagtgg gtcaggcact gatttcacac tgaaaatcag ccgggtggag gctgaagatg
      361 ttggggttta ttactgcatg caagatatac agcttccgct cactttcggc ggagggacca
      421 aggtggagat caaacgag
//
LOCUS       KCVT01007861             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:26716:7884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007861
VERSION     KCVT01007861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26716:7884"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85386.1"
                     /translation="CQQYNSLPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          112 c          106 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagttgaccc agtctccagc
      121 ctccctgtct gcttctgttg gagacagagt caccatcact tgtcgggcaa gtcagggcat
      181 tagcagttac ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatacagat cgtttggaaa ctggggtccc atcaagattc agcggccatg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaactt attactgtca
      361 acagtataat agtttaccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007862             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:15966:4788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007862
VERSION     KCVT01007862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15966:4788"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85387.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           94 a          119 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctcctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctaatcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggagtgg cacctgcaga agccaggcca
      241 gtctctacaa ctcttgattt atgaggtttc ctaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tatttctgca tgcaggctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007863             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:13308:11579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007863
VERSION     KCVT01007863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13308:11579"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85388.1"
                     /translation="CQQYNSLPLTF"
     J_segment       386..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          108 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcaac agaaaccggg gaaagcccct aaggtcctga
      241 tctattatac aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgca agttattact
      361 gtcaacagta taatagttta ccgttgacgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007864             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:10970:11559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007864
VERSION     KCVT01007864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10970:11559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85389.1"
                     /translation="CQQYDSFPLTF"
     J_segment       385..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          117 c          108 g           97 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtgggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtaa ttatttaaat tggtatcagc agaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg ggaagcgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga ggattttgcg acttatcatt
      361 gtcagcagta tgatagtttc cccctcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01007865             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:4473:18250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007865
VERSION     KCVT01007865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4473:18250"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..310
                     /note="immunoglobulin light chain variable region"
     V_region        36..310
     V_segment       36..272
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85390.1"
                     /translation="CQQYNSDPYTF"
     J_segment       273..310
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>313
                     /gene="IGKC"
BASE COUNT           82 a           75 c           86 g           70 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtctccat cacttgtcgg
       61 gcgagtcagg gcattagaag ttatttagcg tggtatcagc tgagaccagg gaaagccccg
      121 aaggccttaa tctattacgc gaccattttg gaaagtgggg tcccatcaag gttcagcggc
      181 agtggatctg ggacagaatt cactctcacc atcagcagcc tgcagcctga ggattttgca
      241 acttatttct gtcaacagta taacagtgac ccgtacactt ttggccaggg gaccaaagtg
      301 gagatcaaac gag
//
LOCUS       KCVT01007866             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:23482:19268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007866
VERSION     KCVT01007866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23482:19268"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..456
                     /note="immunoglobulin light chain variable region"
     V_region        117..456
     V_segment       117..419
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85391.1"
                     /translation="CMQALEFPWTF"
     J_segment       420..456
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>459
                     /gene="IGKC"
BASE COUNT          103 a          122 c          128 g          106 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggatc acgactcctc aggtcacctt ctcacaatga
       61 ggctccctgc tcagctcctg ggactgctaa tgctctggct ccctggatcc agtggggaca
      121 ttgtgatgac ccagactcca gtctccctgc ccgtcaccct gggagagccg gcctccatct
      181 cctgcaggtc tagtcagagc ctcttggata gtgaggatgg aaacacctat ttggaatggc
      241 acctgcagag gccaggccag tctccacagc tcttgattta tgaggtttcc tatcgggcct
      301 ctggagtccc agacaggttc agtggcagtg ggtcagacac tgatttcaca ctgaaaatca
      361 gcagagtgga ggctgaggat gttggtattt attactgcat gcaagctcta gagtttcctt
      421 ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007867             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:20895:10625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007867
VERSION     KCVT01007867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20895:10625"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85392.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007868             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5858:19097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007868
VERSION     KCVT01007868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5858:19097"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85393.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          118 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007869             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:10900:14867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007869
VERSION     KCVT01007869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10900:14867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85394.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          111 a          117 c          107 g           87 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcagag ccagtcagga
      181 tattaacaac tggttggcct ggtatcaaca gaaaccaggg aaagccccta aggtcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcaagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcacca tcaacaacct gcagcctgaa gatatcgcaa catattcctg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01007870             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:19680:17763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007870
VERSION     KCVT01007870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19680:17763"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..409
                     /note="immunoglobulin light chain variable region"
     V_region        96..409
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85395.1"
                     /translation="CQQYNNLPLTF"
     J_segment       383..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>420
                     /gene="IGKC"
BASE COUNT          106 a          111 c          106 g           97 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcgtctgta ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttagcaatta tttaaattgg tatcaacaga aaccggggaa agcccctaag ctcctgatct
      241 attatacaaa ccgtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgagga ttttgcaact tattcctgtc
      361 aacagtataa taatttaccg ttgacgttcg gccaagggac catggtggat ttcaaacgag
//
LOCUS       KCVT01007871             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14567:9567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007871
VERSION     KCVT01007871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14567:9567"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85396.1"
                     /translation="CQQDFGWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          119 c          115 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tccagccatt ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gactgttggc agcgccttag cctggtacca gcagaaacct ggacagactc acaaactcct
      241 catttatggt gcatccagca gggccaccgg catcccagac aggttcagtg gcagtgggtc
      301 tggaacagag ttcactctca ccatcagtag tccggagcct gaggatgttg gagtttatta
      361 ctgtcagcag gattttggct ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007872             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14613:11610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007872
VERSION     KCVT01007872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14613:11610"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85397.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           92 a          117 c          127 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcgcc cttggagagc cggcctccat ctcctgtggg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01007873             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:24145:13285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007873
VERSION     KCVT01007873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24145:13285"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85398.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          116 g          107 t
ORIGIN      
        1 acatggggga tcacaactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01007874             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:18651:8441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007874
VERSION     KCVT01007874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18651:8441"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85399.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          122 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgatgat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcactggcag tgggtctgac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007875             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11346:7778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007875
VERSION     KCVT01007875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11346:7778"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85400.1"
                     /translation="CLQYKSYPFTF"
     J_segment       384..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>424
                     /gene="IGKC"
BASE COUNT          106 a          111 c          105 g          102 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcatggaca tgagggcccc cgctcatctc
       61 ctagggctct tgctgctctg gctcccaggt gccagatgtg acatccaact gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac agtgtcacca tcacttgccg ggcaagtcag
      181 ggtattagta gttatttaaa ttggtttcag cagaaaacag ggaaggcccc taagctcctg
      241 atctatgctg catccagttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggattt
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aagttattac
      361 tgtctacagt ataaaagtta cccattcact ttcggccccg ggaccaaact ggacatcaaa
      421 ggag
//
LOCUS       KCVT01007876             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:19237:22235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007876
VERSION     KCVT01007876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19237:22235"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85401.1"
                     /translation="CLQFKSYPNSF"
     J_segment       386..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          106 g          100 t
ORIGIN      
        1 acatggggga gtcagacaca gtcaggacac agcttggaca tgagggcccc cgctcatctc
       61 ctagggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gactcagtct
      121 ccatcttccc tgtctgcatc tgtaggagac actgtcacca tcacttgccg ggcaagtcag
      181 agtattagta ctcatttaag ttggtttcag cagaaaccag ggaaagcccc taagctcctc
      241 atctatgctg catccagttt ggccggtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtctacagt ttaaaagtta cccgaacagt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007877             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:26509:16042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007877
VERSION     KCVT01007877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:26509:16042"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85402.1"
                     /translation="CQQHNTYPYTF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          106 a          117 c          104 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc caaatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcat
      181 tagtaatgat ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatctt
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca ccagcctgca gcctgaagat tttgcaagtt attactgtca
      361 acagcataat acttacccgt acacttttgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007878             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:15102:6142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007878
VERSION     KCVT01007878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15102:6142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85403.1"
                     /translation="CQQDYDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          103 a          121 c          112 g           89 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gatacagtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 gagtgttggc agcaccttag tatggtacca ccagaaacct gggcaggctc ccacgctcct
      241 cgtctatggt acatccatca gggccaccgg catcccagac aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagact gaagatattg gagtttatta
      361 ttgtcagcag gattatgatt ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007879             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:9727:17110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007879
VERSION     KCVT01007879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9727:17110"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..379
                     /note="immunoglobulin light chain variable region"
     V_region        119..379
     V_segment       119..342
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85404.1"
                     /translation="CQQNSNWPLTF"
     J_segment       343..379
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>382
                     /gene="IGKC"
BASE COUNT           92 a          108 c          105 g           77 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtga tgacgcagtc
      121 tcctgcaggg ccagtcagag tgtcagcagc agcttagcct ggtaccaaca aaaacctggg
      181 caggctccca ggctcctcat ctatggtgca tccagcaggg ccactggcat cccagacagg
      241 ttcagtggca gtgggtctgg gacagacttc actctcacca tcaccagcct ggagcctgaa
      301 gatgttgcag tctatttttg tcagcagaat agtaactggc ctctcacttt cggtggaggg
      361 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007880             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:18924:4717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007880
VERSION     KCVT01007880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18924:4717"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..371
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85405.1"
                     /translation="CQQYDDYPWTF"
     J_segment       383..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          111 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagttcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca aagtcacctt cacttgccat gccagtcagg
      181 gtattagtag tcggttagtc tggtatcagc agaaagcagg gaaagcccct aagcccctga
      241 tgtatgatgc atccagttta cacagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacggatta cactctcacc atcagcagcc tgcagcctga agattttaca acttattact
      361 gtcaacagta tgatgattac ccgtggacct tcggccaagg gaccaaggtg gaaatcaagc
      421 gag
//
LOCUS       KCVT01007881             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:15748:4027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007881
VERSION     KCVT01007881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15748:4027"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85406.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           93 a          117 c          122 g          107 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 ctctccctgc ccgtcactct tggagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctgcagaa gccaggccag
      241 tctccacagc tcttgattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaagatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttcctc tcactttcgg tggagggacc
      421 aaggtggaga tcaaacgag
//
LOCUS       KCVT01007882             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:6583:17073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007882
VERSION     KCVT01007882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6583:17073"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85407.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          119 c          106 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagt tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007883             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19082:18064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007883
VERSION     KCVT01007883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19082:18064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85408.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          116 c          124 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgtccgtcac tcttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatgtggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007884             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:10807:9635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007884
VERSION     KCVT01007884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10807:9635"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85409.1"
                     /translation="CQQYDSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          102 a          118 c          115 g           90 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg cgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 gggcattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007885             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:10638:19356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007885
VERSION     KCVT01007885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10638:19356"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85410.1"
                     /translation="CQQHDDSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          109 a          117 c          109 g           90 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagtca
      181 gggtattaat aactggttgg cctggtatca acagaaacca ggaaaagccc ctaaactcct
      241 tatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcggtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatatcg caacatattt
      361 ctgtcaacag catgatgatt cccctcggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007886             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:7343:6438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007886
VERSION     KCVT01007886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7343:6438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85411.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          112 a          116 c          103 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcacgatat
      181 taacaactgg ttggcctggt atcaacagaa accagggaaa gcccctaagg tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc attaaggttc agtggaagtg gttctgggac
      301 agatttcact ctcaccatca acaacctgca gcctgaagat atcgcaacat attactgtca
      361 acaacatgat gattcccctc ggaccttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007887             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:11134:18343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007887
VERSION     KCVT01007887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11134:18343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85412.1"
                     /translation="CQQYNSDPRTF"
     J_segment       387..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          118 c          111 g           92 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccatatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt ataacagtga cccgcgcact ttcggtggag ggaccaaggt ggacatcaaa
      421 cgag
//
LOCUS       KCVT01007888             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:17969:9010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007888
VERSION     KCVT01007888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17969:9010"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85413.1"
                     /translation="CQQYDSDPRTF"
     J_segment       382..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          111 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaatcgag
//
LOCUS       KCVT01007889             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11241:7381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007889
VERSION     KCVT01007889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11241:7381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..419
                     /note="immunoglobulin light chain variable region"
     V_region        100..419
     V_segment       100..369
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85414.1"
                     /translation="CLQGYYSPYNF"
     J_segment       384..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>424
                     /gene="IGKC"
BASE COUNT           99 a          115 c          112 g           98 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcctc ggtaggagac agagtcacca tcacttgccg ggcaagtcgg
      181 gacattagcg attatttaag ttggtatcag cagaaaccag gagaagctcc taagcgcctg
      241 atctatgctg catccagttt gcaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacactat tcactctcac catcagcagc ctgcagcctg aagattttgc agcttattac
      361 tgtctgcagg gttattattc cccgtacaat tttggccagg ggaccaaagt ggagatcaag
      421 cgag
//
LOCUS       KCVT01007890             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:16849:14757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007890
VERSION     KCVT01007890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16849:14757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85415.1"
                     /translation="CLQYKTYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          103 g           99 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagcacttat ttaagttact ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa acttaccctc tcactttcgg cggggggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01007891             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:10948:5207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007891
VERSION     KCVT01007891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10948:5207"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..423
                     /note="immunoglobulin light chain variable region"
     V_region        84..423
     V_segment       84..385
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85416.1"
                     /translation="CMQPLEFPWTF"
     J_segment       386..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           95 a          111 c          117 g          103 t
ORIGIN      
        1 acatgggagg tcaccttctc acaatgaggc tccctgctca gctcctggga ctgctaatgc
       61 tctggctccc tggatccagt ggggacattg tgatgaccca gattccactc tccctgcccg
      121 tcacccttgg agagccggcc tccatctcct gcaggtctag tcagagtctc ttggatagtg
      181 aggatggaaa cacttatttg gaatggtacc tgcagaagcc aggccagtct ccacagctct
      241 tgatttatga ggtttccaac cgggcctctg gagtcccaga caggttcagt ggcattgggt
      301 cagacactga tttcacactg aaaatcagca gagtggaggc tgaggatgtt ggggtttatt
      361 actgcatgca acctctagag tttccgtgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007892             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16983:6957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007892
VERSION     KCVT01007892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16983:6957"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..409
                     /note="immunoglobulin light chain variable region"
     V_region        126..409
     V_segment       126..371
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85417.1"
                     /translation="CMQALEFPWTF"
     J_segment       372..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           94 a          103 c          116 g           99 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctcca tctcctgtag gtctagtcag agcctcttgg atagtgagga tggaaacacc
      181 tatttggaat ggtacctgca gaagccaggc cagtctccac agctgttgat ttatgaggtt
      241 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      301 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      361 ctagagtttc cgtggacgtt cggccaaggg accaaggtgg aattcaaacg ag
//
LOCUS       KCVT01007893             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23467:17964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007893
VERSION     KCVT01007893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23467:17964"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85418.1"
                     /translation="CMQALEFPLTF"
     J_segment       240..277
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>280
                     /gene="IGKC"
BASE COUNT           71 a           60 c           83 g           66 t
ORIGIN      
        1 acatgggggt caagtcagag cctcctggat agtgaggatg gaaacaccta tttgcactgg
       61 tacttgaaga agccaggcca gtctccacag ctcttaattt atgaggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      181 agcagagtgg aggctgagga tgttggggtt tattactgca tgcaagctct agagtttccg
      241 ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007894             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14787:6101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007894
VERSION     KCVT01007894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14787:6101"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85419.1"
                     /translation="CLQPLEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctaca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cttgcaacct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007895             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:20336:12544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007895
VERSION     KCVT01007895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20336:12544"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85420.1"
                     /translation="CQQYNSSPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          115 c          103 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg accgagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaaccat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga agattttgca acttattact
      361 gtcaacagta taacagtagc ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01007896             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:23825:14956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007896
VERSION     KCVT01007896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23825:14956"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85421.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          120 c          120 g          102 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag gtcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007897             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7414:14187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007897
VERSION     KCVT01007897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7414:14187"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85422.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          104 a          126 c          120 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcagaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acaggttcag
      301 tggcagtggg tctgggacag acttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01007898             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15068:16796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007898
VERSION     KCVT01007898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15068:16796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85423.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          120 g          107 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtccagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggttcctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccatacg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagtaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tcctctcact ttcggcggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007899             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:15048:12762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007899
VERSION     KCVT01007899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15048:12762"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85424.1"
                     /translation="CQQHDNAPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          117 c          115 g           84 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 agtattaacg actggttggc ctggtatcaa cagagaccag ggaaggcccc taagctcctg
      241 atctataggg catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aagtggatct
      301 gggacagatt tcactctcag catcagcagc ctgcagcctg aagatatcgc aacatattac
      361 tgtcagcagc atgacaatgc cccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01007900             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20724:5473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007900
VERSION     KCVT01007900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20724:5473"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85425.1"
                     /translation="CQQGNSIPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          113 c          106 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgtccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagcagttat ttaaattggt atcagcagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatgcagac agtttgtcaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctaaagat tttgcaacct attactgtca
      361 acagggtaat agtattccat tcactttcgg ccccgggacc aaagtggata tcaaacgag
//
LOCUS       KCVT01007901             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21345:14024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007901
VERSION     KCVT01007901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21345:14024"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85426.1"
                     /translation="CQQHADSPRTF"
     J_segment       387..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          120 c          107 g           88 t
ORIGIN      
        1 acatgggggg agtcagtctc agacaggaca cagcatggac acgagggtcc ccgctcagct
       61 cctggggctc ctgttgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgca cagccagcca
      181 cgatataaat aattggttgg cctggtatca acagaaacca ggaaaagccc ctaacctcct
      241 gatctatagg gcatccaatt tggaaacagg ggtcccatcg aggttcagtg gaagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagatttcg caacatatta
      361 ctgtcaacag catgctgatt cccctcggac gttcggccaa gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007902             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25194:6861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007902
VERSION     KCVT01007902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25194:6861"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..443
                     /note="immunoglobulin light chain variable region"
     V_region        122..443
     V_segment       122..401
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85427.1"
                     /translation="CQQYDSDSLTF"
     J_segment       406..443
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>446
                     /gene="IGKC"
BASE COUNT          109 a          121 c          117 g           99 t
ORIGIN      
        1 acatggggag gctaggcacg cttcatgcag gagtcagacc cagtcaggac acagcatgga
       61 catgagggtc cccactcagc tcctaggact cctgctgctc tgtctcccag gtgccaaatg
      121 tgacatccag atgacccagt ctccatcctc cctgtctgca tctgtaggag acagagtctg
      181 catcacttgt cgggcgactc aggacattcg cagttattta gcgtggtatc agcagaaacc
      241 agggaaagcc ccgaagccct tgatctatta cgcgtccact ttggaaagtg gggtcccatc
      301 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      361 tgaagatttt gcaacttatt actgtcaaca gtatgacagt gattcgctca ctttcggtgg
      421 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01007903             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:20390:3999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007903
VERSION     KCVT01007903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20390:3999"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85428.1"
                     /translation="CQQNSNWSLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggtctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007904             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:6837:5880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007904
VERSION     KCVT01007904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:6837:5880"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85429.1"
                     /translation="CLQFKTYPNSF"
     J_segment       382..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           96 a          118 c          105 g          101 t
ORIGIN      
        1 acatggggca gacacagtca ggacacagca tggacatgag ggcccccgct catctcctag
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgact cagtctccat
      121 cttccctgtc tgcatctgta ggagacactg tcaccatctc ttgccgggca agtcagggta
      181 ttagcagttc tttaagttgg tttcagcaga aaccagggaa agcccctcag ctcctcatct
      241 atgctgcatc cagtttggcc ggtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattctc tctcaccatc accagcctgc agcctgaaga ttttgcaact tatttctgtc
      361 tgcagtttaa aacttacccg aacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01007905             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19154:16767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007905
VERSION     KCVT01007905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19154:16767"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85430.1"
                     /translation="CQQGYTYLYSF"
     J_segment       379..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          103 a          115 c          105 g           97 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccccgct cagctccttg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacg cagtctccat
      121 cctccctgtc cgcatctgta ggagacacag tcaccatcac ttgccaggcg agtcaagcca
      181 ttgccaataa tttaaattgg tatcagcaga aaccaggaaa agcccctaaa gtcctgatct
      241 atagggcatc cagtttgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cggatttcac tctcaccatc agcagcctgc agcctgaaga ttttgccact tattactgtc
      361 aacagggtta tacttacctg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01007906             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:14789:19142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007906
VERSION     KCVT01007906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14789:19142"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..357
                     /note="immunoglobulin light chain variable region"
     V_region        36..357
     V_segment       36..320
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <297..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85431.1"
                     /translation="CQQHADSPRTF"
     J_segment       322..357
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>360
                     /gene="IGKC"
BASE COUNT           93 a           97 c           91 g           79 t
ORIGIN      
        1 acatggggtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
       61 cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc agtcagggta
      121 ttagcaactg gttggcctgg tatcaacaga gaccagggaa agcccctaag gtcctgattt
      181 ataggacatc caatttggaa acaggggtcc catcaaggtt cagtggaacc ggatctggga
      241 cagatttcac tctcaccatc agcagcctgc agcctgaaga tttcgctaca tattactgtc
      301 aacagcatgc tgattcccct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01007907             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9340:6565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007907
VERSION     KCVT01007907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9340:6565"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85432.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          117 c          119 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acttatttca cactgaaaat cagcagagtg gaggctgagg
      361 atattggggt ttattattgc atgcaaactc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007908             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21480:23943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007908
VERSION     KCVT01007908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21480:23943"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85433.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           95 a          117 c          106 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctgcatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccagggggcc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007909             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:17031:18511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007909
VERSION     KCVT01007909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17031:18511"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85434.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..412
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>419
                     /gene="IGKC"
BASE COUNT          104 a          113 c          111 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 taggagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagg ccttgatcta
      241 ttacacatcc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaactcact ctcaccatca gcagcctgca gcctgaggat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc agagtggaga tccaacgag
//
LOCUS       KCVT01007910             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14734:4165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007910
VERSION     KCVT01007910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14734:4165"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85435.1"
                     /translation="CQQYDSFPLTF"
     J_segment       386..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          118 c          108 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtgggagac agagtcacca tcacttgccg ggctagtcag
      181 gacattagta attttttaaa ttggtatcag cagaaaccgg ggaaagcccc taagctcctg
      241 atctattatg gaaaccgttt gggaagcggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg acgattttgc gacttatcat
      361 tgtcagcagt atgatagttt ccccctcact ttcggccccg ggaccaaact ggatatcaaa
      421 cgag
//
LOCUS       KCVT01007911             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:10329:5725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007911
VERSION     KCVT01007911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10329:5725"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..386
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85436.1"
                     /translation="CQQYNSDPFTF"
     J_segment       387..424
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          110 a          116 c          107 g           94 t
ORIGIN      
        1 acatggggga ggagtcagac ccagtcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctaggac tcctgctgct ctgtctccca ggtgccaaat gtgacatcca gatgacccag
      121 tctccatcct ccctgtctgc atctgtagga gacagagtaa ccatcacttg tcgggcgagt
      181 caggacataa gaagttattt agcgtggtat cagcagaaag caggcaaagc cccgaagccc
      241 ttgatctatt acgcatccgt tttggaaagt ggggtcccat caaggttcag tggcagtgga
      301 tctgggacag aattcactct caccatcagc agtctgcagc ctgaggattt tgcaacttat
      361 tactgtcaac agtataacag tgacccattc actttcggcc ccgggaccaa actggatacc
      421 aaacgag
//
LOCUS       KCVT01007912             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:16844:3636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007912
VERSION     KCVT01007912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16844:3636"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85437.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctccag aagccaggcc
      241 agtctccaca tctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccagggga
      421 tcaaggtgga aatcaaacga g
//
LOCUS       KCVT01007913             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9466:11117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007913
VERSION     KCVT01007913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9466:11117"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    172..326
                     /note="immunoglobulin light chain variable region"
     V_region        172..326
     V_segment       172..285
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <268..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85438.1"
                     /translation="CQQSYRYPLTF"
     J_segment       291..326
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>331
                     /gene="IGKC"
BASE COUNT           72 a           94 c           91 g           74 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag gagtggggtc
      181 ccatcaaggt tcagcggcag tggatctggg acagatttca ctctcgccat cagcagcctg
      241 cagcctgaag atgctgcaac ttattactgt cagcagagtt atcgttatcc gctcactttc
      301 ggtggaggga cccaggtgga aatcaatcga g
//
LOCUS       KCVT01007914             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:6518:15586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007914
VERSION     KCVT01007914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6518:15586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..383
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85439.1"
                     /translation="CLQGDSTPFTF"
     J_segment       390..413
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>424
                     /gene="IGKC"
BASE COUNT          102 a          115 c          112 g           95 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc ttctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcttccc tgtctgcatc ggtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg attatttaag ttggtatcag cagaaaccgg gaaaagctcc taagcgccta
      241 atctatgctg catccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagagt tcactctcac catcagcagc ctgcagcctg aagattttgc gacttattac
      361 tgtctacagg gtgatagtac cccgttcact tttggccagg ggaccaaagt ggacgtcaaa
      421 cgag
//
LOCUS       KCVT01007915             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:27970:7967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007915
VERSION     KCVT01007915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:27970:7967"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..436
                     /note="immunoglobulin light chain variable region"
     V_region        99..436
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85440.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..436
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>441
                     /gene="IGKC"
BASE COUNT           93 a          121 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga aatcaagcga g
//
LOCUS       KCVT01007916             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:12366:8238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007916
VERSION     KCVT01007916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12366:8238"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..337
                     /note="immunoglobulin light chain variable region"
     V_region        16..337
     V_segment       16..295
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>309
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85441.1"
                     /translation="CQQYDSDSLTF"
     J_segment       300..337
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        338..>340
                     /gene="IGKC"
BASE COUNT           88 a           88 c           86 g           78 t
ORIGIN      
        1 acatgggcca aatgtgacat ccagatgacc cagtctccat cctccctgtc tgcatctgta
       61 ggagacagag tcaccatcac ttgtcgggcg actcaggaca ttcgcagtta tttagcgtgg
      121 tatcagcaga aaccagggaa agccccgaag cccttgatct attacgcgtc cactttggaa
      181 agtggggtcc catcaaggtt cagcggcagt ggatctggga cagaattcac tctcaccatc
      241 agcagcctgc agcctgaaga ttttgcaact tattactgtc aacagtatga cagtgattcg
      301 ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007917             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:25794:6099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007917
VERSION     KCVT01007917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25794:6099"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85442.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           95 a          118 c          122 g          109 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagtctctt ggatagtgag gatggaaaca cctatttgga atggtacttg cagaaggcag
      241 gccagtctcc acagctcttg atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gccactgatt tcaaactgaa catcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tcctctcact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01007918             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11741:16723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007918
VERSION     KCVT01007918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11741:16723"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..383
                     /note="immunoglobulin light chain variable region"
     V_region        62..383
     V_segment       62..331
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <323..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85443.1"
                     /translation="CLQGDTAPFTF"
     J_segment       348..383
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>386
                     /gene="IGKC"
BASE COUNT           89 a          106 c          101 g           90 t
ORIGIN      
        1 acatggggtc cccgctcagc tcctggggct ccttctgctc tggctcccag gtgccagatg
       61 tgacatccag atgacccagt ctccatcttc cctgtctgca tcggcaggag acagagtcac
      121 catcacttgc cgggcaagtc agggcattaa cgattattta agttggtatc agcagaaacc
      181 aggaaaacct cctaagcgcc tgatttatgc tgcatccagt ttggaaagtg gggtcccatc
      241 aaggttcagc ggcagtggat ctgggacaga attcactctc accatcagca gcctgcagcc
      301 tgaagatttt gcagcttatt actgtctaca gggtgatact gccccgttca ctttcggcgg
      361 agggaccaag gtggagatca aacgag
//
LOCUS       KCVT01007919             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:21678:9266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007919
VERSION     KCVT01007919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21678:9266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..375
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85444.1"
                     /translation="CQQHNNYSPTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          121 c          107 g           91 t
ORIGIN      
        1 acatgggggg agtcagaacc cctcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccaccctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagc aatgatttag cctggtatca gctgaaacca gggaaagccc cgaagcccct
      241 gatctattac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa cataataatt actctcccac tttcggcgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007920             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:23318:8777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007920
VERSION     KCVT01007920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23318:8777"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85445.1"
                     /translation="CQQYNSLPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          109 c          112 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattgaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcgttaac gtttatttaa attggtatca gcagaaaccg gggaaagccc ctaagcccct
      241 gatcttttat gcaaaccgtt tggaacgtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caagttatta
      361 ttgtcaacag tataatagtt taccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007921             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:13143:2215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007921
VERSION     KCVT01007921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13143:2215"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85446.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          119 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgct aatgctctgg ctccctgggt ccagtgggga cattgtgttg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcata
      181 gcctcttgga tggtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007922             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:24205:7796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007922
VERSION     KCVT01007922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24205:7796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85447.1"
                     /translation="CQQYNSDPFTF"
     J_segment       380..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          115 c          104 g           93 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag taaccatcac ttgtcgggcg agtcaggaca
      181 taagaagtta tttagcgtgg tatcagcaga aagcaggcaa agccccgaag cccttgatct
      241 attacgcatc cgttttggaa agtggggtcc catcaaggtt cagtggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagtctgc agcctgagga ttttgcaact tattactgtc
      361 aacagtataa cagtgaccca ttcactttcg gccccgggac caaactggat accaaacgag
//
LOCUS       KCVT01007923             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:25118:8865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007923
VERSION     KCVT01007923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25118:8865"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85448.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          122 c          119 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattctgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttccattg gtacctggag aagccaggcc
      241 agtctccaca gctcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007924             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:2996:13519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007924
VERSION     KCVT01007924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:2996:13519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..270
                     /note="immunoglobulin light chain variable region"
     V_region        100..270
     V_segment       100..233
                     /gene="IGKV1-16"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <210..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85449.1"
                     /translation="CQQHNGYPPTF"
     J_segment       236..270
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>273
                     /gene="IGKC"
BASE COUNT           67 a           74 c           75 g           57 t
ORIGIN      
        1 acatgggggt cagaaccact caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac atccaatttg gaaagtgggg
      121 tcccatcaag gttcagcggc agtggatctg ggacagattt cactctcacc atcagcagcc
      181 tgcagcctga agattttgca acttattatt gtcaacagca taatggatac cctccgacgt
      241 tcggccaagg gaccagggtg gaaatcaaac gag
//
LOCUS       KCVT01007925             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17944:17036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007925
VERSION     KCVT01007925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17944:17036"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85450.1"
                     /translation="CQQYDSDSLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           94 t
ORIGIN      
        1 atgggggagt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgactcagga
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat gacagtgatt cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007926             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:11060:15090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007926
VERSION     KCVT01007926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11060:15090"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85451.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc aaaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007927             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:23471:2500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007927
VERSION     KCVT01007927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23471:2500"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85452.1"
                     /translation="CMQALDFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT          101 a          120 c          118 g          104 t
ORIGIN      
        1 acatggggat gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccattggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac caatttggaa tggttcctgc agaagccagg
      241 ccagtctcca caactcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg atttattact gcatgcaagc tctagacttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007928             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:19811:15087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007928
VERSION     KCVT01007928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19811:15087"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85453.1"
                     /translation="CQQYNSLPYIF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          111 c          106 g           99 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccatcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 gacattagcg tttttttaaa ttggtatcag cagaaaccgg ggaaagcccc taaacccctg
      241 atctattatg caaaccgttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accgtacatt tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007929             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:12025:15848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007929
VERSION     KCVT01007929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12025:15848"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85454.1"
                     /translation="CMQALDFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtaatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ttcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcggtggcag tgtcccagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagactttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007930             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:11738:22994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007930
VERSION     KCVT01007930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11738:22994"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85455.1"
                     /translation="CQQVYSNPFTF"
     J_segment       379..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           98 a          114 c          103 g          104 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gtccctgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgatatc cagatgaccc agtctccttc
      121 tgccttgtct gcatctgtag gggacagagt caccatctct tgccgggcaa gtcagaacat
      181 ttatagttat ttagcgtggt atcagcagaa accagggaaa gcccctaagc tcctgatcta
      241 tgctgtatcc agattgcaaa gtgggattcc ctctcggttc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tctgcaactt attactgtca
      361 acaggtttat agtaacccat tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007931             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:8816:7696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007931
VERSION     KCVT01007931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8816:7696"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85456.1"
                     /translation="CVQAIAFPLTF"
     J_segment       394..431
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           90 a          120 c          122 g          102 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctggatccag tggggatatt gtaatgaccc agactccact
      121 ctccctgccc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggaaaca cctttttgca ctggtacctg cagaagccag gccagtctcc
      241 gcagctcctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcagg ctatagcgtt tccgctcact ttcggtggag ggaccaaggt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01007932             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:21022:16556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007932
VERSION     KCVT01007932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21022:16556"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85457.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           98 a          117 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagattcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacactta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcatt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007933             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:22233:11430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007933
VERSION     KCVT01007933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22233:11430"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85458.1"
                     /translation="CQQYNNDPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          112 c          112 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccaggtga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcagga
      181 cattagaagt tatttagcgt ggtatcagat gagaccaggg aaagccccga gggccttaat
      241 ctattacgcg accattttgg aaggtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcggcagcct gcagcctgag gattttgcaa cttatttctg
      361 tcaacagtat aacaatgacc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01007934             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:8924:16431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007934
VERSION     KCVT01007934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8924:16431"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85459.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          115 c          111 g           95 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtt gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01007935             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:21981:17011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007935
VERSION     KCVT01007935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21981:17011"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85460.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007936             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:13962:6597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007936
VERSION     KCVT01007936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13962:6597"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85461.1"
                     /translation="CQHGYGIPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          117 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagtcccag tcaggacaca gcatggacat gagggccccc actcagctcc
       61 tggggttcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccaatctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccag gcgagtcagg
      181 ccattagtaa taatttagtc tggtatcagc agcaaccggg gaaagcccct aagctcctga
      241 tctataaggc atccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcagcatgg ttatggtatc ccgtggacgt tcggccaagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007937             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21461:18438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007937
VERSION     KCVT01007937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21461:18438"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85462.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          106 t
ORIGIN      
        1 actggggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctcatgctct ggctccctgt atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atgtcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc ggtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 tgatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01007938             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:9066:11494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007938
VERSION     KCVT01007938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9066:11494"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85463.1"
                     /translation="CMQALEFPLTF"
     J_segment       405..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          104 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgct gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgtag gtctagtcag
      181 agcctcttgg atagtgagga tggaaatacc tatttggaat ggcaccggca gatgccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctgacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01007939             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:13147:15304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007939
VERSION     KCVT01007939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13147:15304"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85464.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tcaagtcaga
      181 gcctcctgga tagtgaggat ggaaacacct atttgcactg gtacttgaag aagccaggcc
      241 agtctccaca ggtcttaatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007940             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:19773:3944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007940
VERSION     KCVT01007940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19773:3944"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85465.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          117 c          106 g           86 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gccacgatat
      181 aaataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaagc tcctgatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc agtggaagtg gatctgggac
      301 agatttcact ctcagcatca gcagcctgca gcctgaagat ttcgcaacat attactgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007941             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19343:10025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007941
VERSION     KCVT01007941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19343:10025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85466.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          118 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tatgaagttt ccaaccgggc ctccggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007942             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12721:9605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007942
VERSION     KCVT01007942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12721:9605"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85467.1"
                     /translation="CQQYDSDTRTF"
     J_segment       391..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          104 a          117 c          116 g           91 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgag
      181 tcagggcatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gagttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagtatgaca gtgacacgcg cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01007943             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15097:11343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007943
VERSION     KCVT01007943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15097:11343"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85468.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          117 g           89 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc agcagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc accatcagta gtccggaacc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccagg gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007944             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18661:13347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007944
VERSION     KCVT01007944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18661:13347"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85469.1"
                     /translation="CQQDYSWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          119 c          118 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttgtcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagtcac cctctcctgc agggccagtc
      181 agagtgttgg cagcatctta gcctggtacc accagaaacc tgggcaggct cccaagtccc
      241 tcatctatgg tgcaaccagt agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggcgtttatt
      361 actgtcagca ggattatagc tggccactca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007945             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:14368:11341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007945
VERSION     KCVT01007945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14368:11341"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85470.1"
                     /translation="CQQYNTLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          110 a          109 c          106 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 gcattagtag ttatttaaat tggtatcaac taaaaccggg gaaagcccct aagctcctga
      241 tctattatac aaaccgtttg gaaagagggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaaactga ggattttgca acttattatt
      361 gtcaacagta taatacttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007946             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:13507:11117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007946
VERSION     KCVT01007946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13507:11117"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85471.1"
                     /translation="CQQHNSYPRTF"
     J_segment       385..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          118 c          108 g           92 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcgttagcaa ttatttagcc tggtatcagc agaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccattttg gaaagtgggg tcccatcaag attcagcggc cgtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca agttattact
      361 gtcaacagca taatagttat cctcggacgt tcggccaggg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007947             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:17141:16080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007947
VERSION     KCVT01007947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17141:16080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..377
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85472.1"
                     /translation="CQQYNNLPYTF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT          105 a          112 c          101 g          100 t
ORIGIN      
        1 acatgggaga cccagtcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca gtctccatcc
      121 tccctgtctg cttctttagg agacagagtc accatcactt gccgagcaag tcaggacatt
      181 agcagttttt tgaattggta tcagcagaaa ccggggaaag cccctaacct cctgatctat
      241 tttgcaaacc gtttggagag tggggtccca tcaaggttca gcggcagtgg gtctgggaca
      301 agattcactc tcaccatcag cagcctccaa cctgaagatt ttgcaactta ttactgtcaa
      361 cagtataata atttaccgta cacttttggc caggggacca aagttgagat caaacgag
//
LOCUS       KCVT01007948             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:20804:8551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007948
VERSION     KCVT01007948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20804:8551"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85473.1"
                     /translation="CLQGDTAPLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           99 a          114 c          114 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtgg gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgattat ttaagttggt atcagcagag accaggaaaa actcctaggc gcctgatcta
      241 tgctgcatcc agtttgggaa gtggggtccc gtcaagattc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagggtgat actgccccgc tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007949             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:13163:9437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007949
VERSION     KCVT01007949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13163:9437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV3-52"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85474.1"
                     /translation="CQNYNDWPLTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>426
                     /gene="IGKC"
BASE COUNT           96 a          122 c          116 g           92 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaactgtg atgatgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccaggc
      181 agagtattgg cagcacctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctattc tgcatccacc agggccactg gcatcccaga caggttcagt ggtagtgggt
      301 ctgggtcaga tttcactctc accatcagca gtctggatcc tgaagatgtt ggagtttatt
      361 actgtcagaa ttacaatgac tggccgctca ctttcggtgg agggaccaag gtggagatca
      421 gacgag
//
LOCUS       KCVT01007950             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:15466:11883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007950
VERSION     KCVT01007950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15466:11883"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85475.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          118 c          122 g          108 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007951             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15824:7616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007951
VERSION     KCVT01007951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15824:7616"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..438
                     /note="immunoglobulin light chain variable region"
     V_region        120..438
     V_segment       120..403
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85476.1"
                     /translation="CQQHNSYPLTF"
     J_segment       405..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>444
                     /gene="IGKC"
BASE COUNT          113 a          125 c          113 g           93 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggga gtcagaacca ctcaggacac agcatggaca
       61 tgagggtccc cgctcagctc ctggggctcc tgctgctctg gctcccaggt gccagatgtg
      121 acatccagat gacccagtct ccatcctccc tgtctgcatc tgtaggagac acagtcacca
      181 tcacttgtcg ggcaagtcag ggcattacca atgatttagc ctggtatcag cagaaaccag
      241 ggaaagcccc gaagcccctg atctattacg catccaattt ggaaactggg gtcccatcaa
      301 ggttcagcgg cagtggatct gggacagatt tcactctcac catcagcagc ctgcagcctg
      361 aagattttgc aacttattac tgtcaacagc ataatagtta cccactcact ttcggcggag
      421 ggaccaaggt ggagatcaga cgag
//
LOCUS       KCVT01007952             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16121:8955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007952
VERSION     KCVT01007952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16121:8955"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85477.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          101 a          124 c          109 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctaca tactaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcaga gatttcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01007953             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18020:16621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007953
VERSION     KCVT01007953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18020:16621"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85478.1"
                     /translation="CQQVLTNPAF"
     J_segment       388..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          113 c          109 g           99 t
ORIGIN      
        1 acatgggggg gagtcagtct cagtcaggac acagcatgga catgagggtc cctgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgatatccag gtgacccagt
      121 ctccatctgc cttgtctgca tctgtaggag acagagtcac catctcttgc cgggcaagtc
      181 agaacattta taggaattta gcgtggtatc agcagaaacc agggaaagcc cctaaactcc
      241 tgatctatgc tgcatccaga ttgcaaagtg ggtttccctc tcggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca acctacagcc tgaagattct gcaatttatt
      361 actgtcaaca ggttcttact aacccggcgt tcggccaagg gaccaaggtg gaaatcaaac
      421 gag
//
LOCUS       KCVT01007954             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13841:11266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007954
VERSION     KCVT01007954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13841:11266"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85479.1"
                     /translation="CQQYDSDPFTF"
     J_segment       386..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          110 g           93 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgagtcag
      181 ggcattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa gattcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacctattac
      361 tgtcaacagt atgacagtga tccgttcact ttcggtgggg ggaccaaggt agacatcaaa
      421 cgag
//
LOCUS       KCVT01007955             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16908:7475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007955
VERSION     KCVT01007955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16908:7475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85480.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 acttctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01007956             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:21192:16521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007956
VERSION     KCVT01007956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21192:16521"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85481.1"
                     /translation="CQQDFDWPPTF"
     J_segment       388..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          100 a          126 c          111 g           88 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagctc cagcacagct
       61 tctcttcctc ctgctactct ggatcccaga taccaccgga gaagttgtga tgacgcagtc
      121 tccagccacc ctgtctttgt ctccagggga aagagccacc ctctcctgca gggccagtca
      181 aagtgttggc aacaccttaa cctggtacca gcacaaacct gggcaggctc ccaagctcct
      241 cctctatggt gcatccacca gggcctccgg catcccaggc aggttcagtg ccagtgggtc
      301 tggaacagag tttactctca ccatcagcag cctggagcct gaagatgttg gaatttatta
      361 ctgtcagcag gattttgact ggcctccgac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007957             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:6938:9938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007957
VERSION     KCVT01007957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6938:9938"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85482.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          122 g          107 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggg tccagtgggg acattgtgtt gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcat
      181 agcctcttgg atggtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007958             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:8215:18558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007958
VERSION     KCVT01007958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8215:18558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..438
                     /note="immunoglobulin light chain variable region"
     V_region        102..438
     V_segment       102..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85483.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           93 a          118 c          123 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggggg cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007959             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:15858:8444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007959
VERSION     KCVT01007959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15858:8444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85484.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          116 c          109 g           94 t
ORIGIN      
        1 acatgggaga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007960             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:18216:9735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007960
VERSION     KCVT01007960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18216:9735"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85485.1"
                     /translation="CMQALEFPWTF"
     J_segment       405..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttttgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagagtt tccttggacg ttcggccaag
      421 ggaccagggt ggaaatcaaa cgag
//
LOCUS       KCVT01007961             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17823:6095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007961
VERSION     KCVT01007961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17823:6095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85486.1"
                     /translation="CQQHNTYPYTF"
     J_segment       386..423
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          108 a          118 c          107 g           93 t
ORIGIN      
        1 acatggggag gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct cctgctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acacagtcac catcacttgt cgggcaagtc
      181 agggcattag taatgattta gcctggtatc agcagaaacc agggaaagcc ccgaaacccc
      241 tgatctttta cgcatccaat ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gcataatact tacccgtaca cttttggcca ggggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007962             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:26061:5854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007962
VERSION     KCVT01007962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:26061:5854"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85487.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          118 g          105 t
ORIGIN      
        1 acagggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgctg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 acctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gagcctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007963             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:11718:17852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007963
VERSION     KCVT01007963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11718:17852"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..367
                     /gene="IGKV1-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85488.1"
                     /translation="CQQYYSFPITF"
     J_segment       381..413
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT           99 a          112 c          111 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agttcctggg
       61 gctcctgctg ctctggatcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacaaagt caccatcact tgccgagcca gtcagggtat
      181 taacacctgg ttaatttggt atcagcagaa accagggaaa gcccctaagg ccctgatcta
      241 taaggcatcc agtttgcaag gtggggtccc ttccaggttc agcggcagtg gatctggggc
      301 agacttcact ctcaccatca ccaacctgca gcctgaagat tttggaattt attactgtca
      361 acaatattat agttttccga tcactttcgg tggggggacc aaggtggaga tcaggcgag
//
LOCUS       KCVT01007964             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13284:7701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007964
VERSION     KCVT01007964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13284:7701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85489.1"
                     /translation="CQQYNSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          110 a          108 c          107 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagttattat ttaaattggt atcaacagaa accggggaaa gcccctaagg tcctgatcta
      241 ttacacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaagtt attactgtca
      361 acaatataat agtttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01007965             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:2910:14915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007965
VERSION     KCVT01007965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:2910:14915"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85490.1"
                     /translation="CQQHNNYSPTF"
     J_segment       386..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          122 c          105 g           90 t
ORIGIN      
        1 acatggggag tcagaaccac tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggcc ccagatgtga catccagatg acccagtctc
      121 caccctccct gtctgcatct gtaggagaca cagtcaccat cacttgtcgg gcaagtcagg
      181 gcattagcaa tgatttagcc tggtatcagc tgaaaccagg gaaagccccg aagcccctga
      241 tctattacgc atccaatttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagattt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagca taataattac tctcccactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007966             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19050:10276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007966
VERSION     KCVT01007966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19050:10276"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..376
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85491.1"
                     /translation="CQQGHSYPLTF"
     J_segment       384..419
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          101 a          121 c          105 g           95 t
ORIGIN      
        1 acatgggggt cagtctcagt caggacacag catggacatg agggtccccg ctcagctcct
       61 tgggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga cgcagtctcc
      121 atcctccgtg tccgcatctg taggagacac agtcacgatc acttgccagg cgagtcaagg
      181 cattggcaaa agtttaagtt ggtatcagca gaaaccaggg aaagccccta acctcctgat
      241 ctatagggca tccaatttac aaagtgggat tccctctcgg ttcagcggca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt catagttacc cactcacttt cggccccggg accaaactgg atatcaaacg
      421 ag
//
LOCUS       KCVT01007967             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19140:16310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007967
VERSION     KCVT01007967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19140:16310"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85492.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccacg actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007968             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:18741:9816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007968
VERSION     KCVT01007968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18741:9816"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85493.1"
                     /translation="CQQYDSDPFSF"
     J_segment       388..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttctctt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01007969             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:23649:15379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007969
VERSION     KCVT01007969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23649:15379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85494.1"
                     /translation="CGQGTHLPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           92 a          125 c          120 g           93 t
ORIGIN      
        1 acctggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccactggg gatgttgtga tgactcagtc tccgctctcc
      121 ctgcccatca cccctggaca gccggcctcc gtctcctgca ggtctagtca aagccttgtg
      181 cacagcgatg gaaacacata cttgacttgg tatcaacaga agccaggcca acctccaagg
      241 cgcctaattt ttgaggtttc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgacga tgttggggtt
      361 tattactgcg gccaaggtac acaccttccg tggacgttcg gccaagggac cacggtggaa
      421 ctcaaacgag
//
LOCUS       KCVT01007970             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:23406:4195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007970
VERSION     KCVT01007970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23406:4195"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85495.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttggg tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01007971             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16540:21731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007971
VERSION     KCVT01007971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16540:21731"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85496.1"
                     /translation="CQHSFRSPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          117 c          108 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggcctct gctcagctcc
       61 tagggctcct gctgctctgg ctcccaggcg ccagatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccgt cacttgcagg gctagtgaga
      181 gcgttagcac caaattacat tggtatcaac agaaaccagg gaaagcccct aagctcctga
      241 tctttgctgc gtccactttg caaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 gaacagattt cactctcacc atcagcagcc tgcagcctga agatgttgca actttttact
      361 gtcagcatag ttttcgttcc ccgtacagtt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01007972             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:26295:9291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007972
VERSION     KCVT01007972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26295:9291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85497.1"
                     /translation="CLQYKSYPLTF"
     J_segment       380..415
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>419
                     /gene="IGKC"
BASE COUNT          106 a          112 c          103 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcttgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatatgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tagcacttat ttaaattggt ttcagcagaa accagggaaa gcccctagac tcctgatcta
      241 tgctgcatcc agtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca ccagcctgca gcctgaagat tttgcaactt atcactgtct
      361 acagtataaa agttaccctc tcactttcgg cggagggacc aaggtggaga tcaaaagag
//
LOCUS       KCVT01007973             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:25538:12168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007973
VERSION     KCVT01007973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25538:12168"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85498.1"
                     /translation="CQQYNNDPPTF"
     J_segment       382..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          121 c          102 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtctccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tggcagtcat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcatcc aatttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtataac aatgaccctc ccactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01007974             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:22953:13260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007974
VERSION     KCVT01007974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22953:13260"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85499.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcaggc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01007975             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8320:19048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007975
VERSION     KCVT01007975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8320:19048"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85500.1"
                     /translation="CQQYNSLPYSF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          106 a          109 c          111 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattgaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 gggcgttaac gtttatttaa attggtatca acagaaaccg gggaaagccc ctaagcccct
      241 gatcttttat gcaaaccgtt tggaacgtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caagttatta
      361 ttgtcaacag tataatagtt taccgtacag ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01007976             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:22377:20394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007976
VERSION     KCVT01007976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22377:20394"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85501.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttggc tagtgaagat ggaaacacgt atttggaatg gtatctgcag aagccaggcc
      241 agtctccaca gctctggatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007977             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21599:14478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007977
VERSION     KCVT01007977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21599:14478"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..429
                     /note="immunoglobulin light chain variable region"
     V_region        108..429
     V_segment       108..392
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85502.1"
                     /translation="CLQYKSFPLTF"
     J_segment       393..429
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          104 a          113 c          111 g          104 t
ORIGIN      
        1 acatgggggc ttgcaggagt cagacacagt caggacacag catggacatg agggcccccg
       61 ctcatctcct agggctcctg ctgctctggc tcccaggtgc cagatgtgac atccagatga
      121 ctcagtctcc atcttccctg cctgcatctg tgggggacac tgtcaccatc acttgccggg
      181 caagtcagga tattaacagt tatttaaatt ggtttcagca gaaaccaggg aaagccccaa
      241 aggtcctgat ccatgctgca tccagtttgg aaagtggggt cccgtctagg ttcagcggca
      301 gtggatctgg gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa
      361 cttattattg tctacagtat aaaagttttc ctctcacttt cggtggaggg accaaggtgg
      421 atatcaaacg ag
//
LOCUS       KCVT01007978             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:6442:8154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007978
VERSION     KCVT01007978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6442:8154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85503.1"
                     /translation="CQQHDNSPRTF"
     J_segment       388..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          113 a          119 c          107 g           87 t
ORIGIN      
        1 acatggggag gagtcagtct cagacaggac acagcatgga cacgagggtc cccgctcagc
       61 tcctggggct cctgttgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgc acagccagcc
      181 acgatataaa taactggttg gcctggtatc aacagaaacc aggaaaagcc cctaagctcc
      241 tgatctatag ggcatccaat ttggaaacag gggtcccatc gaggttcagt ggaagtggat
      301 ctgggacaga tttcactctc accatcagca gcctgcagcc tgaagatttc gcaacatatt
      361 actgtcaaca gcatgataat tcccctcgga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01007979             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:22557:16545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007979
VERSION     KCVT01007979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22557:16545"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..327
                     /note="immunoglobulin light chain variable region"
     V_region        128..327
     V_segment       128..290
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <267..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85504.1"
                     /translation="CMQALEFPLTF"
     J_segment       291..327
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>330
                     /gene="IGKC"
BASE COUNT           89 a           83 c           90 g           68 t
ORIGIN      
        1 acatgggtaa ctcccaggag agtgtcacag agcaggacag caaggacaac acctacagcc
       61 tgagcagcac cctgacgctg agcagcacag actaccagag tcacaatgtc tatgcctgcg
      121 aagtcaccca gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc
      181 cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg
      241 aggctgagga tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg
      301 gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01007980             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:6707:12961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007980
VERSION     KCVT01007980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6707:12961"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85505.1"
                     /translation="CMQSLEFPWTS"
     J_segment       404..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           91 a          118 c          125 g          109 t
ORIGIN      
        1 acatgggggt gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttgggga gccggcctcc atctcctgta ggtctagtca
      181 gagcctcttg gatgttgaag atggaaacac ctatttggac tggtacctgc agaagccagg
      241 ccagtctcca cagctcttgg tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtctg acactgattt cacactgaaa atcagtagag tggaggctga
      361 ggatgttggg ttttatttct gcatgcagag tctggagttt ccttggacgt ccggccaagg
      421 gaccaaggtg gaagtcaaac gag
//
LOCUS       KCVT01007981             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:12520:3017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007981
VERSION     KCVT01007981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12520:3017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85506.1"
                     /translation="CLQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgacg
      361 atgttggggt ttattactgc ttgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaagctgga aatcaaacga g
//
LOCUS       KCVT01007982             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19635:15892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007982
VERSION     KCVT01007982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19635:15892"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..435
                     /note="immunoglobulin light chain variable region"
     V_region        98..435
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85507.1"
                     /translation="CMQSLDFPLTF"
     J_segment       400..435
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>440
                     /gene="IGKC"
BASE COUNT           95 a          121 c          119 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgttatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttggaatgg tacttgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagccc cagacaggtt
      301 cagtggcagt gggtcagaca cagatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcagtctct agattttccg ctcaccttcg gtggagggac
      421 caaggtggag atcaatcgag
//
LOCUS       KCVT01007983             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16316:20365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007983
VERSION     KCVT01007983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16316:20365"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85508.1"
                     /translation="CMQALDFPLTF"
     J_segment       402..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tctagtgggg acattgtaat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tttcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcggtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttggga tttattactg catgcaagct ctagactttc cgctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01007984             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:16756:7193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007984
VERSION     KCVT01007984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16756:7193"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85509.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat aagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007985             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:7685:21786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007985
VERSION     KCVT01007985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7685:21786"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85510.1"
                     /translation="CQQYNSLPLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          114 c          109 g           98 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acattcagat gacccagtct
      121 ccgtcctccc tgtctgcttc tgtaggagac agagtcacca tcacttgccg ggcaagtcag
      181 ggcattagca gttttttaaa ttggtatcga cagaaaccgg ggaaaccccc taacctcctg
      241 atctattatg caaaccgttt ggaaagtggg gtcccttcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcaacctg aagattttgc aacttattac
      361 tgtcaacagt ataatagttt accgctcact ttcggcggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01007986             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:14177:5785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007986
VERSION     KCVT01007986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14177:5785"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85511.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          117 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagcgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01007987             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:12134:13064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007987
VERSION     KCVT01007987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12134:13064"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85512.1"
                     /translation="CLQYKSYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          117 c          105 g          100 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgcccg atgtgacatc ctgatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtct
      181 tagcagttct ttacattggt ttcaacacaa accagggaaa gcccctaggc tcctgatcta
      241 tgctgcatcc agtttggcag gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agacttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa agttacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01007988             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18781:11675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007988
VERSION     KCVT01007988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18781:11675"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..422
                     /note="immunoglobulin light chain variable region"
     V_region        83..422
     V_segment       83..384
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85513.1"
                     /translation="CMQALDFPWTF"
     J_segment       385..422
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT           94 a          112 c          117 g          102 t
ORIGIN      
        1 acatgggggt caccttctca caatgaggct ccctgctcag ctcctgggac tgctaatgct
       61 ctggctccct ggatccagtg gggacattgt actgacccag actccactct ccctgcccgt
      121 cacccttgga gagccggcct ccattttctg taggtctagt cagagcctct tggatagtga
      181 ggatggaaac acctatttgg aatggtacct gcagaagcca ggccagtctc cacagctctt
      241 gatttatgag gtttccgacc gggcctctgg agtcccagac aggttcagtg gcagtgggtc
      301 agacactgat ttcacactga aaatcagcag agtggaggct gaggatgttg ggatttatta
      361 ctgcatgcaa gctctagact ttccgtggac gttcggccaa gggaccaagg tggaaatcaa
      421 acgag
//
LOCUS       KCVT01007989             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:14067:14739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007989
VERSION     KCVT01007989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14067:14739"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85514.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgtaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaataccta tttggaatgg caccggcaga tgccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttcct ctgacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01007990             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:7369:11552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007990
VERSION     KCVT01007990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:7369:11552"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85515.1"
                     /translation="CQQYNSGPFTF"
     J_segment       364..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          103 a          109 c           99 g           93 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctaggactcc tgctgctctg
       61 tctcccaggt gccaaatgtg acatccagat gaccgagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtaacca tcacttgtcg ggcgagtcag gacataagaa gttatttagc
      181 gtggtatcag cagaaaccag gcaaagcccc gaagcccttg atctattacg catccgtttt
      241 ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct gggacagaat tcactctcac
      301 catcagcagt ctgcagcctg aagattttgc aacttattac tgtcaacagt ataacagtgg
      361 cccattcact ttcggccccg ggaccaaact ggatatcaaa cgag
//
LOCUS       KCVT01007991             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:7035:17908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007991
VERSION     KCVT01007991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7035:17908"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85516.1"
                     /translation="CMQSLEIPPTF"
     J_segment       403..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          121 c          120 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctgggtc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtggggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttt cacccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggcgtt tattactgca tgcaatctct agagattcct cccactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01007992             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:21266:11297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007992
VERSION     KCVT01007992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21266:11297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..275
                     /note="immunoglobulin light chain variable region"
     V_region        6..275
     V_segment       6..244
                     /gene="IGKV3-34"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85517.1"
                     /translation="CQKYSSPPFTF"
     J_segment       245..275
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>285
                     /gene="IGKC"
BASE COUNT           66 a           79 c           80 g           60 t
ORIGIN      
        1 acatggggga aagagccacc ctctcctgca gggccagtca gagtgttggc agcagcttag
       61 cctggtacca gcagaaagtt gggcaggccc ccaggctcct catctatggt gcatctagta
      121 gggccactgg catcccagac aggttcagtg gcagtgggtc tgggacagag ttcaccctca
      181 ccatcagcag cctggagcct gaagattttg tagtgtacta ctgtcagaaa tatagtagtc
      241 ccccattcac tttcggcccc gggaccaaac tggatttcag acgag
//
LOCUS       KCVT01007993             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:13094:4681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007993
VERSION     KCVT01007993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13094:4681"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85518.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          117 c          117 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgaa tccagtgggg acattgtgat gacgcagact
      121 ccatactccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctactcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt ctcagacagg
      301 ttcagtggca atgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggttg agatcaaacg ag
//
LOCUS       KCVT01007994             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19912:4828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007994
VERSION     KCVT01007994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19912:4828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85519.1"
                     /translation="CQQYDSFPLTF"
     J_segment       382..417
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT           98 a          118 c          106 g           98 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgacc cagtctccat
      121 cctccctgtc tgcttctgtg ggagacagag tcaccatcac ttgccgggct agtcaggaca
      181 ttagtaattt tttaaattgg tatcagcaga aaccggggaa agcccctaag ctcctgatct
      241 attatggaaa ccgtttggga agcggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc aacctgacga ttttgcgact tatcattgtc
      361 agcagtatga tagtttcccc ctcactttcg gccccgggac caaactggat atcaaacgac
//
LOCUS       KCVT01007995             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:13525:8591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007995
VERSION     KCVT01007995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13525:8591"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85520.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          119 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 cgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcgggc ctctggagtc gcagacaggt
      301 tcagtggcag tgggttaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01007996             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19308:17622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007996
VERSION     KCVT01007996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19308:17622"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85521.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           98 a          121 c          122 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtggatca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctggactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01007997             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:26215:4902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007997
VERSION     KCVT01007997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26215:4902"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85522.1"
                     /translation="CMQYRHIPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          114 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct aatgctctgg ctctctggtt ccagtgggga tgttgtgatg acccagactc
      121 cattccccct gtccgttagc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgaa tagtgaagac ggaaacacct atttggattg gtacctgcag aggccgggcc
      241 agtctccaca gcccttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat taacagagtg gaggctgagg
      361 atgttgggat ttatatctgc atgcaatata gacacattcc attcactttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01007998             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:20063:16330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007998
VERSION     KCVT01007998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20063:16330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..358
                     /gene="IGKV1-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85523.1"
                     /translation="SMHDSEGPTTF"
     J_segment       384..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           97 a          114 c          118 g           92 t
ORIGIN      
        1 acatggggga ggctctgagc accgcctgcc agcatgttct tgggagttca ggtgcagctc
       61 ctctggagcc tggctttctg gagggcagtg agtggagaca tcatcctgaa ccagacgcca
      121 gcatccctga ctgcacctcc aggagagaca gtctccatct cctgccaagc cagagcagat
      181 gtacatggtg aaatgtcttg gatccggata aaccttgaac aaagacttga acccctttta
      241 tctcatgtca ctaccttggc cccaggtgtc gcagcccggt tcatcagcaa ggggagtggc
      301 accagttatg ttttcagcat cagtgacctg cagcctgggg actctgggga ctattactcc
      361 atgcatgact ctgaggggcc aaccactttc ggtggaggga ccaaggtgga gatcaaacga
      421 a
//
LOCUS       KCVT01007999             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:15581:10973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01007999
VERSION     KCVT01007999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15581:10973"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..352
                     /note="immunoglobulin light chain variable region"
     V_region        13..352
     V_segment       13..314
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <292..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85524.1"
                     /translation="CMQALEFPWTF"
     J_segment       315..352
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>355
                     /gene="IGKC"
BASE COUNT           84 a           86 c          103 g           82 t
ORIGIN      
        1 acatggggtg gggacattgt gatgacccag actccagtct ccctgcccgt cacccttaga
       61 gagccggcct ccatctcctg caggtctagt cagagcctct tggatagtga ggatggaaac
      121 acctatttgg aatggtacct acagaggcca ggccagtctc cacagctctt aatttatgag
      181 gtttcctacc gggcctctgg agtcccagac aggttcagtg ggagtgggtc agacactgat
      241 ttcacactga aaatcagcag agtggaggct gaggatgttg gggtttatta ctgcatgcaa
      301 gctctagagt ttccgtggac gttcggccaa gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01008000             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:15677:16305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008000
VERSION     KCVT01008000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15677:16305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85525.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          121 c          117 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagtcac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatgtatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008001             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:15641:13182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008001
VERSION     KCVT01008001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15641:13182"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85526.1"
                     /translation="CQQYNYLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          108 a          112 c          104 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaacc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 acagtataat tatttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01008002             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1110:12770:9953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008002
VERSION     KCVT01008002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12770:9953"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85527.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           97 a          117 c          122 g          106 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tgtcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa ttagcagagt ggaggctgag
      361 gatgttgggg ttttttactg catgcaagct ctagagtttc cgtggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01008003             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19070:10007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008003
VERSION     KCVT01008003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19070:10007"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85528.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggagtg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccaaagtgga gattaaacga g
//
LOCUS       KCVT01008004             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:20075:14283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008004
VERSION     KCVT01008004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20075:14283"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85529.1"
                     /translation="CQHSFRTPYSF"
     J_segment       380..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          100 a          115 c          109 g           96 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacagag tcaatgtcac ttgcagggct agtgagagcg
      181 ttagcaccaa attacattgg tatcagcaga aaccagggaa agcccctaag ctcctgatct
      241 ttgctgcgtc cactttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggaa
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga tgtcgcaact ttttactgtc
      361 agcatagttt tcgtaccccg tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01008005             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:11514:18646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008005
VERSION     KCVT01008005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11514:18646"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85530.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           99 a          117 c          118 g          108 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgaa tccagtgggg acattgtgat gacgcagact
      121 ccatactccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtctactcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca gaagccaggc
      241 cagtctccac acctcttgat ttatgaggtt tccaaccggg cctctggagt ctcagacagg
      301 ttcagtggca atgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggttg agatcaaacg ag
//
LOCUS       KCVT01008006             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:26122:17248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008006
VERSION     KCVT01008006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26122:17248"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85531.1"
                     /translation="CLHYKSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          105 a          116 c           99 g          103 t
ORIGIN      
        1 acatgggggg tcagacacag tcaggacaca gcatggacat gagggccccc gctcatctcc
       61 tagggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg actcagtctc
      121 catcttccct gtctgcatct gtgggagaca ctgtcaccat cacttgccgg acaagtcaag
      181 gtcttaccaa ttatttacat tggtttcagc agaagccagg gaatgcccct aagttcctga
      241 tctatgaaac atccactttg gtaagtgggg tcccatcaag gttcagcggc agtgcatctg
      301 ggacagaatt cactctcacc atcagcagcc tacagcctga agattttgca tcttattact
      361 gtctacacta taaaagtttg ccgtacactt ttggccaggg gaccaaagtc gagatcaaac
      421 gag
//
LOCUS       KCVT01008007             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:14432:11243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008007
VERSION     KCVT01008007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14432:11243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85532.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           97 a          126 c          118 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaggagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccggg caggttccgt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008008             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:11248:10985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008008
VERSION     KCVT01008008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11248:10985"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85533.1"
                     /translation="CMQALDFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          120 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagactttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008009             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:23863:16270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008009
VERSION     KCVT01008009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23863:16270"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85534.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          121 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggccgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008010             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:17075:15885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008010
VERSION     KCVT01008010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17075:15885"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85535.1"
                     /translation="CQQYDSFPPTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          107 a          113 c          105 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatcta taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattatcagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattataca aaccgtttgg aaactggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc accctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagtat gatagttttc ctcccacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01008011             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:16835:5243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008011
VERSION     KCVT01008011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16835:5243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85536.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggggagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008012             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:17585:3468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008012
VERSION     KCVT01008012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17585:3468"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85537.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          123 c          117 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc cgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008013             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:9455:9001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008013
VERSION     KCVT01008013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9455:9001"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85538.1"
                     /translation="CQQGYSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          101 a          120 c          108 g           94 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gcaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattggcaa tactttaaat tggtatcaac agaaaccggg gaaagcccct acactcctga
      241 tctatagggc atccggtttg caaagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttat ccgtacagtt ttggccaggg gaccaaactg gagatcaaac
      421 gag
//
LOCUS       KCVT01008014             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:9348:10034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008014
VERSION     KCVT01008014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9348:10034"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85539.1"
                     /translation="CQQHNTYPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          118 c          107 g           93 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 ggcattagta atgatttagc ctggtatcag cagaaaccag ggaaagcccc gaagcccctg
      241 atcttttacg catccaattt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagc ataatactta cccgtacact tttggccagg ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008015             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:3442:8691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008015
VERSION     KCVT01008015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3442:8691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85540.1"
                     /translation="CQQYNSDPFTF"
     J_segment       385..422
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          110 a          117 c          104 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtaacc atcacttgtc gggcgagtca
      181 ggacataaga agttatttag cgtggtatca gcagaaacca ggcaaagccc cgaagccctt
      241 gatctattac gcatccgttt tggaaagtgg ggtcccatca aggttcagtg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag tctgcagcct gaagactttg caacttatta
      361 ctgtcaacag tataacagtg acccattcac tttcggcccc gggaccaaac tggatatcaa
      421 acgag
//
LOCUS       KCVT01008016             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:12851:15849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008016
VERSION     KCVT01008016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12851:15849"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..366
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85541.1"
                     /translation="CLQGYSPPFTF"
     J_segment       367..404
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           96 a          112 c          103 g           96 t
ORIGIN      
        1 acatggggga cacagcatgg acatgagggt ccccgctcag ctcctggggc tccttctgct
       61 ctggctccca ggtgccagat gtgacatcca gatgacccag tctccatctt ccctgtctgc
      121 atcggtagga gacagagtca ccatcacttg ccgggcaagt caggacatta gcgattattt
      181 aagttggtat caacagaaac caggaaaaac tcctgagcgc ctgatctatg ctgcatccag
      241 tttggaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag aattcactct
      301 caccatcagc agcctgcagc ctgaagattt tgcaggttat ttctgtctac agggttatag
      361 tcccccattc actttcggcc ccgggaccaa actggatttc aaacgag
//
LOCUS       KCVT01008017             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6324:15659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008017
VERSION     KCVT01008017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6324:15659"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..329
                     /note="immunoglobulin light chain variable region"
     V_region        8..329
     V_segment       8..291
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <269..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85542.1"
                     /translation="CLHYNSDPWTF"
     J_segment       292..329
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>332
                     /gene="IGKC"
BASE COUNT           90 a           79 c           80 g           83 t
ORIGIN      
        1 acatggggac atccagatga cccagtctcc atcttccctg tctgcatctg taagagacag
       61 agtcaccttc acttgcaggg caagtcaggg cattacaact tttttaaatt ggtgtcagca
      121 gaaatcagga aaaactccta agcgcctgat ctgtgttgaa tacagtttgg aaagtggggt
      181 cccatcaagg ttcagtggca gtggatctgg gacaggtttc actctcacca tcagcagcct
      241 gcagcctgaa gattttacaa cttattcctg tcttcattat aacagtgacc cgtggacgtt
      301 cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01008018             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4606:11540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008018
VERSION     KCVT01008018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4606:11540"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..240
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <217..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85543.1"
                     /translation="CMQALEFPFTF"
     J_segment       242..275
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>280
                     /gene="IGKC"
BASE COUNT           65 a           60 c           86 g           69 t
ORIGIN      
        1 acatgggggt ctagtcagag cctctttgat attgaggagg ggaccaccta tttggaatgg
       61 tacctgcaga ggcctggcca gtctccacag ctcttgattt atgaggtttc caaccgggcc
      121 tctggagtcc cagacaggtt cagtggcagt gggtcagaca ctgatttcac actgaaaatc
      181 aacagagtgg aggctgagga tggtggggtt tattactgca tgcaagctct agagtttcct
      241 ttcactttcg gcggagggac caaggtggag atcaagcgag
//
LOCUS       KCVT01008019             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:15806:4898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008019
VERSION     KCVT01008019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15806:4898"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85544.1"
                     /translation="YMQALEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          122 c          117 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc ctcggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccatccgggc ctctggagtc ccagacaggt
      301 tcagtggcaa tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggagt ttattactac atgcaagctc tagaatttcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008020             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:12137:12828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008020
VERSION     KCVT01008020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12137:12828"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85545.1"
                     /translation="CLQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          105 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtgagg atggaaacac ctatttggaa tggtacctac agaagcctgg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagac tggaggctga
      361 ggatgttggg gtttattact gcttgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01008021             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:23135:8315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008021
VERSION     KCVT01008021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23135:8315"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85546.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          116 c          126 g          105 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagcgggg acattgtgat gacccagact
      121 ccactctccc tgtccgtcac ccttggagag ccggcctcca tctcctgcag gtcaagtcag
      181 agcctcttgg atggtgagga tggaatcacc tacttggaat ggtatttaca gaaggcaggc
      241 cagtctccgc aggtcttgat ttatgaggtt tacaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcagg cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttatcactg catgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01008022             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10231:14492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008022
VERSION     KCVT01008022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10231:14492"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85547.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          125 c          114 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg atgacgcact
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008023             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:24144:20437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008023
VERSION     KCVT01008023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24144:20437"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85548.1"
                     /translation="CQQDFDWPPTF"
     J_segment       384..418
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT           99 a          126 c          109 g           87 t
ORIGIN      
        1 acatggggac tgctcagtta ggacccagag ggaaccatgg aagctccagc acagcttctc
       61 ttcctcctgc tactctggat cccagatacc accggagaag ttgtgatgac gcagtctcca
      121 gccaccctgt ctttgtctcc aggggaaaga gccaccctct cctgcagggc cagtcagagt
      181 gttggcaaca ccttaacctg gtaccagcac aaacctgggc aggctcccaa gctcctcctc
      241 tatggtgcat ccaccagggc caccggcatc ccagacaggt tcagtgccag tgggtctgga
      301 acagagttta ctctcaccat cagcagcctg gagcctgaag atgttggaat ttattactgt
      361 cagcaggatt ttgactggcc tccgacgttc ggccaaggga ccaaggtgga aatcaaacga
      421 g
//
LOCUS       KCVT01008024             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:22382:17822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008024
VERSION     KCVT01008024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22382:17822"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85549.1"
                     /translation="CQQYNSDPRTF"
     J_segment       388..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          105 a          118 c          111 g           91 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgagtca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaacccc cgaagccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacag tataacagtg acccgcgcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01008025             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:14610:12490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008025
VERSION     KCVT01008025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14610:12490"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..275
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85550.1"
                     /translation="CEQYNSLPYTF"
     J_segment       276..313
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>316
                     /gene="IGKC"
BASE COUNT           91 a           77 c           71 g           77 t
ORIGIN      
        1 acatgggagt ctccatcctc cctgtctgct tctgtaggag acagagtcac catcacttgc
       61 cgggcaagtc aggacattaa catttattta aattggtatc accagaaacc ggggaaagcc
      121 cctaagctcc tgatctatta tacaaaccgt ttggaaagtg gggtcccatc aaggttcagc
      181 ggcagtggat ctgggacaga attcactctc accatcagca gcctgcaacc tgaagatttt
      241 gcaacttatt actgtgaaca atacaatagt ttaccgtaca cttttggcca ggggaccaaa
      301 gtggagatca aacgag
//
LOCUS       KCVT01008026             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:15951:18691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008026
VERSION     KCVT01008026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15951:18691"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..371
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85551.1"
                     /translation="CLQGDTAPFTF"
     J_segment       388..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          115 c          116 g           94 t
ORIGIN      
        1 acatgggggg gagtcagaac cactcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctggggct ccttctgctc tggctcccag gtgccagatg tgacatccag atgacccagt
      121 ctccatcttc cctgtctgca tcggcaggag acagagtcac catcacttgc cgggcaagtc
      181 agggcattaa cgattattta agttggtatc ggcagaaacc aggaaaacct cctaagcgcc
      241 tgatttatgc tgcatccagt ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcagcttatt
      361 actgtctaca gggtgatact gccccgttca ctttcggcgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008027             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12458:11380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008027
VERSION     KCVT01008027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12458:11380"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..427
                     /note="immunoglobulin light chain variable region"
     V_region        91..427
     V_segment       91..389
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85552.1"
                     /translation="CGQGTHLPLTF"
     J_segment       390..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g           95 t
ORIGIN      
        1 acagggggga tcaggactcc tcagttcacc atgaggctcc ctgctcagct cctggggctg
       61 ctattgctct gcgtccccgg atccagtggg gatgttgtga tgagtcagtc tccactctcc
      121 ctgcccatca cccctggaca gccggcctcc atctcctgca ggtctagtca aagccttgta
      181 cacatcactg gaaacacata cttgagttgg tatcagcaga agtcaggcca acctccaagg
      241 cgcctaattt atgaggtctc taaccgggac tctggggtcc cagacagatt cagcggcagt
      301 ggggcaggga cagatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt
      361 tattattgcg gtcaaggtac acaccttccg ctcactttcg gcggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01008028             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:12667:5083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008028
VERSION     KCVT01008028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12667:5083"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85553.1"
                     /translation="CQQDFGWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          100 a          119 c          116 g           89 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aaatagtgat gacgcagtct
      121 ccagccattc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 actgttggca gcgccttagc ctggtaccag cagaaacctg ggcagactca caaactcctc
      241 atttatggtg catccagcag ggccaccggc atcccagaca ggttcagtgg cagtgggtct
      301 ggaacagagt tcactctcac catcagtagt ccggagcctg aggatgttgg agtttattac
      361 tgtcagcagg attttggctg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01008029             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:8425:14374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008029
VERSION     KCVT01008029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8425:14374"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-44"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85554.1"
                     /translation="CLQYNSNPPTF"
     J_segment       382..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          107 g           96 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgtcag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcgtctgtgg gagacagagt caccatcact tgcagggcaa gtcagggcat
      181 cagcacttat ttaaattggt atcagcagaa accaggaaaa cctcctaagc gcctcttcta
      241 tggtgcatcc agtttcggaa gtggggtccc atcaaggttc agcggcagtg gatcagggac
      301 aactttcact ctcaccatca gtagcctgca gcctgaagat tttgcgactt atttctgtct
      361 acagtataat agtaaccctc cgacgttcgg ccaggggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01008030             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14417:7427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008030
VERSION     KCVT01008030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14417:7427"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85555.1"
                     /translation="CQQYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          102 a          112 c          110 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtgg gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtctatat ttaaattggt atcaacagaa accggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 gcagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01008031             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:7379:18527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008031
VERSION     KCVT01008031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7379:18527"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..374
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85556.1"
                     /translation="CQQYDSDSLTF"
     J_segment       379..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          114 c          108 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga ctcaggacat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc actttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attattgtca
      361 acagtatgac agtgattcgc tcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01008032             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:9311:18029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008032
VERSION     KCVT01008032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9311:18029"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85557.1"
                     /translation="CLQGYITPYSF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          102 a          113 c          113 g          100 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctccttctgc tctggctccc aggtgccaga tgtgacttcc agatgaccca
      121 gtctccatct tccctgtctg catcggtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt agcgattttt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg
      241 cctgatttat gctgcatcca gtttgcaaag tggggtcccg tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcggctta
      361 ttactgtcta cagggttata ttaccccgta cagttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01008033             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:24548:7361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008033
VERSION     KCVT01008033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24548:7361"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85558.1"
                     /translation="CHQYNNLPLTF"
     J_segment       380..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          109 a          113 c          101 g           96 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccactc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 taacatttat ttaaattggt atcagcagaa accggggaaa gcccctaagc tcctgatcta
      241 ttatgcaaat cgtttggaaa ctggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca acagcctgca acccgaagat tttgcaactt attactgtca
      361 ccagtataat aatttaccac tcactttcgg cggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01008034             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:21486:19328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008034
VERSION     KCVT01008034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21486:19328"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85559.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgtctcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgagaat cagtagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008035             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:18063:11240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008035
VERSION     KCVT01008035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18063:11240"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85560.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctactgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008036             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:19668:13313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008036
VERSION     KCVT01008036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19668:13313"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..459
                     /note="immunoglobulin light chain variable region"
     V_region        120..459
     V_segment       120..421
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <399..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85561.1"
                     /translation="CMQALEFPWTF"
     J_segment       422..459
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>462
                     /gene="IGKC"
BASE COUNT          102 a          125 c          131 g          104 t
ORIGIN      
        1 acatgggggt caacgcagag tacatggggg atcacgactc ctcaggtcac cttctcacaa
       61 tgaggctccc tgctcagctc ctgggactgc taatgctctg gctccctgga tccagtgggg
      121 acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag ccggcctcca
      181 tctcctgcag gtctagtcag agcctcttgg atggtgagga tggaaacacc tatttggagt
      241 ggcacctgca gaagccaggc cagtctccac agctcttgat ttatgaggtt tccaaccggg
      301 cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc acactgaaaa
      361 tcagcagagt ggaggctgag gatcttgggg tttattactg catgcaagct ctagagtttc
      421 cgtggacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01008037             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17363:23025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008037
VERSION     KCVT01008037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17363:23025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..365
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85562.1"
                     /translation="CLQGDTAPFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          114 c          111 g           93 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctccttct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cttccctgtc tgcatcgaca ggagacagag tcaccatcac ttgccgggca agtcagggca
      181 ttaacgatta tttaagttgg tatcagcaga aaccaggaaa acctcctaag cgcctgattt
      241 atgctgcatc cagtttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcagct tattactgtc
      361 tacagggtga tactgccccg ttcactttcg gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01008038             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:21121:8825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008038
VERSION     KCVT01008038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21121:8825"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..372
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85563.1"
                     /translation="CLQGDTAPFTF"
     J_segment       389..424
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>427
                     /gene="IGKC"
BASE COUNT          103 a          115 c          115 g           94 t
ORIGIN      
        1 acatggggga ggagtcagaa ccactcagga cacagcatgg acatgagggt ccccgctcag
       61 ctcctggggc tccttctgct ctggctccca ggtgccagat gtgacatcca gatgacccag
      121 tctccatctt ccctgtctgc atcggcagga gacagagtca ccatcacttg ccgggcaagt
      181 cagggcatta acgattattt aagttggtat cagcagaaac caggaaaacc tcctaagcgc
      241 ctgatttatg ctgcatccag tttggaaagt ggggtcccat caaggttcag cggcagtgga
      301 tctgggacag aattcactct caccatcagc agcctgcagc ctgaagattt tgcagcttat
      361 tactgtctac agggtgatac tgccccgttc actttcggcg gagggaccaa ggtggagatc
      421 aaacgag
//
LOCUS       KCVT01008039             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:19835:18137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008039
VERSION     KCVT01008039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19835:18137"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85564.1"
                     /translation="CQQGYSYPYSF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          119 c          109 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gcaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattggcaa tactttaaat tggtatcaac agaaaccggg gaaagcccct acactcctga
      241 tctatagggc atccggtttg caaagtggga ctccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttat ccgtacagtt ttggccaggg gaccaaactg gagatcaaac
      421 ggg
//
LOCUS       KCVT01008040             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:21896:14068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008040
VERSION     KCVT01008040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21896:14068"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..397
                     /note="immunoglobulin light chain variable region"
     V_region        94..397
     V_segment       94..371
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85565.1"
                     /translation="SMHDYGWPTTS"
     J_segment       381..397
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>398
                     /gene="IGKC"
BASE COUNT           89 a          111 c          108 g           90 t
ORIGIN      
        1 acatgggggc tctgagcacc gcctgccagc atgttcttgg gagttcaggt gcagctcctc
       61 tggaacctgg ctttctggag ggcagtgagt ggagacatca tcctgaacca gccgccagca
      121 tccctgactg cacctccagg agagacagtc tccatctcct gccaagccag agcagatgta
      181 catggtgaaa tatcttggat ccggataaac cttgaacaaa gacttgaacc ccttttatct
      241 catgtcacta ccttggcccc aggtgtcgca gcccggttca tcagcaaggg gagtggcacc
      301 agttatgttt tcagcatcag tgacctgcag cctggggact ctggggacta ttactccatg
      361 catgactatg ggtggccaac cacttccggt ggagggaa
//
LOCUS       KCVT01008041             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:22923:10743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008041
VERSION     KCVT01008041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22923:10743"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..404
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85566.1"
                     /translation="CMQSLEIPPTF"
     J_segment       407..441
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          102 a          120 c          116 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc catctcctgc aggtctagtc
      181 aaagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgaga tttccaatcg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtagaggctg
      361 aggatgttgg agtttattac tgcatgcaat ctctagagat tcctcccact ttcggtggag
      421 ggaccaaggt ggagatcaaa cgag
//
LOCUS       KCVT01008042             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12052:14953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008042
VERSION     KCVT01008042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12052:14953"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..283
                     /note="immunoglobulin light chain variable region"
     V_region        7..283
     V_segment       7..246
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85567.1"
                     /translation="CQQDFDWPPTF"
     J_segment       249..283
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>286
                     /gene="IGKC"
BASE COUNT           68 a           81 c           79 g           58 t
ORIGIN      
        1 acatgggggg aaagagccac cctctcctgc agggccagtc agagtgttgg caacacctta
       61 acctggtacc agcacaaacc tgggcaggct cccaagctcc tcctctatgg tgcatccacc
      121 agggcctccg gcatcccagg caggttcagt gccagtgggt ctggaacaga gtttactctc
      181 accatcagca gcctggagcc tgaagatgtt ggaatttatt actgtcagca ggattttgac
      241 tggcctccga cgtttggcca agggaccaag gtggaaatca aacgag
//
LOCUS       KCVT01008043             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:23808:9931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008043
VERSION     KCVT01008043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23808:9931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85568.1"
                     /translation="CQQYNSDPRTF"
     J_segment       393..427
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          105 a          119 c          113 g           93 t
ORIGIN      
        1 acatggggat gcaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctag gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgtcgggcg
      181 agtcagggca ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag
      241 cccttgatct attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcact
      301 ggatctggga cagaattcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact
      361 tatttctgtc aacagtataa cagtgacccg cgcactttcg gtggagggac caaggtggag
      421 atcaaacgag
//
LOCUS       KCVT01008044             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:25375:7867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008044
VERSION     KCVT01008044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25375:7867"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85569.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          119 c          117 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc attggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggccagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01008045             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:10624:14162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008045
VERSION     KCVT01008045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10624:14162"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85570.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          119 c          117 g          108 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catacgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01008046             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:11841:2025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008046
VERSION     KCVT01008046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11841:2025"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85571.1"
                     /translation="CQQYDSDPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          114 c          110 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tagcagttat ttagcgtggt atcagcagaa gccagggaaa gccccgaagc ccttgatcta
      241 tttcgcatcc attttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcgccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01008047             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12465:8698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008047
VERSION     KCVT01008047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12465:8698"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85572.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg acaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagcgta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctttgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008048             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:22399:12033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008048
VERSION     KCVT01008048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22399:12033"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85573.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgttatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggcaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01008049             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:15289:12509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008049
VERSION     KCVT01008049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15289:12509"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85574.1"
                     /translation="CQQHNTYPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          118 c          107 g           93 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacatccaaa tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cacagtcacc atcacttgtc gggcaagtca
      181 gggcattagt aatgatttag cctggtatca gcagaaacca gggaaagccc cgaagcccct
      241 gatcttttac gcatccaatt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagat ttcactctca ccatcaccag cctgcagcct gaagattttg caagttatta
      361 ctgtcaacag cataatactt acccgtacac ttttggccag gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01008050             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18634:12154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008050
VERSION     KCVT01008050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18634:12154"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85575.1"
                     /translation="CLQGYITPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          100 a          113 c          107 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacttc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttgcaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attactgtct
      361 acagggttat attaccccgt acagttttgg ccaggggacc aaactggata tcaaacgag
//
LOCUS       KCVT01008051             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:8503:9899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008051
VERSION     KCVT01008051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8503:9899"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85576.1"
                     /translation="CQQDFDWPPTF"
     J_segment       385..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          100 a          125 c          111 g           86 t
ORIGIN      
        1 acatgggagg aactgctgtt aggacccaga gggaaccatg gaagctccag cacagcttct
       61 cttcctcctg ctactctgga tcccagatac caccggagaa gttgtgatga cgcagtctcc
      121 agccaccctg tctttgtctc caggggaaag agccaccctc tcctgcaggg ccagtcagag
      181 tgttggcaac accttaacct ggtaccagca caaacctggg caggctccca agctcctcgt
      241 ctatggtgca tccaccaggg ccaccggcat cccagacagg ttcagtgcca gtgggtccgg
      301 aacagagttt actctcacca tcagcagcct ggagcctgaa gatgttggaa tttattactg
      361 tcagcaggat tttgactggc ctccgacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01008052             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16361:15680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008052
VERSION     KCVT01008052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16361:15680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85577.1"
                     /translation="CQQYYSTPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          106 a          113 c          122 g          100 t
ORIGIN      
        1 acatggggga gctacaacag gcaggcaggg gcagcaagat ggtgtcacag acccaagtct
       61 tcatttccct gttgctctgg atctctggtg cctgtgggga cattgtgatg acccagtcgc
      121 cagactccct ggctgtgtct ctgggagaga gggtcaccat caactgcaag tccagccaga
      181 gtcttttacg catctccaac aataggaact acttagcctg gtatcagcag aaaccagggc
      241 aggctcctaa actgctcatt tactgggcat ctacccggga attcgggatc cctaaccgat
      301 tcagtggcag tggatctggg tcagatttca ctctcaccat cagtggcctg caggctgaag
      361 atgtggcagt gtattactgt cagcagtatt atagcactcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008053             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:14730:3701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008053
VERSION     KCVT01008053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14730:3701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85578.1"
                     /translation="CQQYNSLPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          102 a          116 c          104 g          101 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga gattcagatg acccagtctc
      121 catcctccct gtctgcctct gtcggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagtgt ttatttaaat tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tttattatgc atcccgtttg gagaatgggg tcccatcaag gttcagcggc tctggatctg
      301 ggacagaatt cagtctcacc atcagcagcc tgcaacctga agattctgca gcttattact
      361 gtcagcagta taatagttta ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01008054             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:9607:13075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008054
VERSION     KCVT01008054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9607:13075"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85579.1"
                     /translation="CQQYDSDPYSF"
     J_segment       383..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          114 c          108 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagctt ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcaggccat
      181 tagcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 tttcgcatct attttggaaa gtggcgtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac agtgacccgt atagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01008055             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:7652:5759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008055
VERSION     KCVT01008055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7652:5759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..371
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85580.1"
                     /translation="CQQGQSYPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 gcattgtcaa taatttaaat tggtatcaac agaaaccagg gaaagcccct aaactcctga
      241 tcgatagggc atccaatttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 ggacggattt cactctcacc atcagcagcc tgcagcctga agattttgcc agttattcct
      361 gtcaacaggg tcaaagttac ccgctcactt tcggcggagg gaccaaggtg gagatgaaac
      421 gag
//
LOCUS       KCVT01008056             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1111:21655:6740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008056
VERSION     KCVT01008056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21655:6740"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85581.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          118 c          118 g          109 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgaat ccagtgggga cattgtgatg acgcagactc
      121 cattctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctactcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca cctcttgatt tctgaggttt ccaaccgggc ctctggagtc tcagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggttga gatcaaacga g
//
LOCUS       KCVT01008057             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:17445:13486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008057
VERSION     KCVT01008057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17445:13486"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85582.1"
                     /translation="CQQYDSDSLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          116 c          110 g           94 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcaccat cacttgtcgg gcgactcagg
      181 acattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aggcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacaata tgacagtgat tcgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008058             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:23310:19683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008058
VERSION     KCVT01008058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23310:19683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85583.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          124 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg ctgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggtcagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccagactcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccagg caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcactttatt
      361 attgtcagca gaacagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008059             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:14457:10982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008059
VERSION     KCVT01008059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14457:10982"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..381
                     /note="immunoglobulin light chain variable region"
     V_region        106..381
     V_segment       106..343
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <321..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85584.1"
                     /translation="CMQALEFPYSF"
     J_segment       344..381
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>384
                     /gene="IGKC"
BASE COUNT           87 a           98 c          106 g           93 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct attgctctgg ctccctggat cacgactcca ctctccctgc aggtctagtc
      121 agagcctcat ggatagtggg gatgtaaaca cctatttgga atggtacctg cagaagccag
      181 gccagtctcc acatctcttg atttatgagg tttccaaccg ggcctctgga gtcccagaca
      241 ggttcagtgg cagtgggtca gacacggatt tcacactgaa aatcagcaga gtggaggctg
      301 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtacagt tttggccagg
      361 ggaccagagt ggagatcaaa cgag
//
LOCUS       KCVT01008060             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:23055:15672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008060
VERSION     KCVT01008060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23055:15672"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..393
                     /gene="IGKV2-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85585.1"
                     /translation="CVQAIAFPYSF"
     J_segment       394..431
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>434
                     /gene="IGKC"
BASE COUNT           94 a          119 c          119 g          102 t
ORIGIN      
        1 acatggggag gactcctcag ttcaccttct cacaatgagg ctccctgctc agttcctggg
       61 gctgctgatg ctctggctcc ctgaatccag tggggatatt gtgatgaccc agactccact
      121 ctccctgtcc atcacccctg gagagccggc ctccatctcc tgcaggtcta gtcagagcct
      181 cctgcatagt aatggaaaca cctatttcca ctggtacctg cagaagccag gccagtctcc
      241 gcagctcctg atttatgggg gttccaacag agcctctgga gtcccagaca ggttcagtgg
      301 cagtgggtca ggcactgatt tcacactgaa aatcagcaag gtggaggcgg aggatgttgg
      361 ggtttattac tgcgtgcaag ctatagcgtt tccgtacagt tttggccagg ggaccaaagt
      421 ggagatcaaa cgag
//
LOCUS       KCVT01008061             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22390:6562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008061
VERSION     KCVT01008061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22390:6562"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85586.1"
                     /translation="CQQYNNLPYTF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          106 a          114 c          109 g           99 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacgttc agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg ggacagagtc accctcactt gccgggctag
      181 tcaggacgtt aacgtttatt taaattggta tcaccagaaa ccggggaaag cccctaagct
      241 cctgatctat tatacaaacc gtttggaaaa tggggtcccg tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaagatt ttgcgactta
      361 ttactgtcaa cagtataata atttaccgta cacttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01008062             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:27395:9017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008062
VERSION     KCVT01008062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27395:9017"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85587.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          117 c          121 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagaatg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01008063             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:18345:9582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008063
VERSION     KCVT01008063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18345:9582"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85588.1"
                     /translation="CQHSFDTPYTF"
     J_segment       385..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          102 a          118 c          108 g           96 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggcctc tgctcagctc
       61 ctagggctcc tgctgctctg gctcccaggc gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag ggcaagtgcg
      181 aacgttaaca actatttaca ttggtatcag cagaaaccag ggaaagtccc tgagctcctg
      241 atctatgctg catcgtcttt gcaaagtggg gtcccatcaa ggttcagcgg cagtgggtct
      301 gggacagatt tcaccctcac catcagcagc ctgcagcctg aagatgttgc aacttattac
      361 tgtcagcaca gttttgatac cccctacact tttggccagg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008064             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:22606:11476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008064
VERSION     KCVT01008064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22606:11476"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..391
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85589.1"
                     /translation="CLQSKNSPWSF"
     J_segment       392..429
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT          100 a          116 c          117 g           99 t
ORIGIN      
        1 acatggggga gcagcctcta gttcagctct cagaaatggg gtcctgggct cctttcctgt
       61 ggatcctcct gctctgtgct ccaggctgca gtggggacat tgtgctgacc cagtctccag
      121 cctctttggc cgtgtctcca gggcagaggg ccaccatcac ctgcagagcc agtgagagtg
      181 tcagtgcctt tggaataagc ctcattcact ggtatcaaca gaaaccagga caacctccta
      241 aactcctgat ttaccaagca atcaataagg agactggggt cccagccagg ttcagcggca
      301 gtgggtctgg gaccgatttc accctcacaa ttaatcctgt ggaacctgac gatggtgcag
      361 attattactg tctgcagagt aagaattctc cgtggtcgtt cggccaaggg accaaggtgg
      421 aaatcaaacg ag
//
LOCUS       KCVT01008065             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12559:14027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008065
VERSION     KCVT01008065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12559:14027"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..398
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85590.1"
                     /translation="CMQALEFPWTF"
     J_segment       399..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           98 a          117 c          121 g          103 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggggaca ttgtgatgac ccagactcca
      121 gtctccctgc ccgtcaccct tagagagccg gcctccatct cctgcaggtc tagtcagagc
      181 ctcttggata gtgaggatgg aaacacctat ttggaatggt acctacagag gccaggccag
      241 tctccacagc tcttaattta tgaggtttcc taccgggcct ctggagtccc agacaggttc
      301 agtggcagtg ggtcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaagctcta gagtttccgt ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01008066             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12469:9512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008066
VERSION     KCVT01008066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12469:9512"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85591.1"
                     /translation="CQQYDSDLFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          114 c          110 g           96 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcattt gtaggagaca gagtcaccat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agaaaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggttctg
      301 ggacagaatt cactctcacc atcaacagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ctgttcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008067             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:11280:19823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008067
VERSION     KCVT01008067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11280:19823"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85592.1"
                     /translation="CMQALDFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT           97 a          120 c          121 g          106 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg ctgacccaga
      121 ctccactctc cctgcccgtc acccttggag agccggcctc cattttctgt aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtacctg cagaagccag
      241 gccagtctcc acagctcttg atttatgagg tttccgaccg ggcctctgga gtcccagcca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg gatttattac tgcatgcaag ctctagactt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01008068             291 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:5712:9330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008068
VERSION     KCVT01008068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 291)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5712:9330"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..246
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85593.1"
                     /translation="CQQYDSDSLTF"
     J_segment       251..288
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>291
                     /gene="IGKC"
BASE COUNT           77 a           68 c           80 g           66 t
ORIGIN      
        1 acatgggtgt aggagacaga gtcaccatca cttgtcgggc gactcaggac attcgcagtt
       61 atttagcgtg gtatcagcag aaaccaggga aagccccgaa gcccttgatc tattacgcgt
      121 ccactttgga aagtggggtc ccatcaaggt tcagcggcag tggatctggg acagaattca
      181 ctctcaccat cagcagcctg caggctgaag attttgcaac ttattactgt caacagtatg
      241 acagtgattc gctcactttc ggtggaggga ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008069             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:19380:7379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008069
VERSION     KCVT01008069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19380:7379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..377
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85594.1"
                     /translation="CQQYNSDWRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           92 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgact ggcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01008070             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:13139:15291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008070
VERSION     KCVT01008070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13139:15291"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..418
                     /note="immunoglobulin light chain variable region"
     V_region        102..418
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85595.1"
                     /translation="CQQDYSWPLTF"
     J_segment       387..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>426
                     /gene="IGKC"
BASE COUNT           98 a          119 c          119 g           90 t
ORIGIN      
        1 atggggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagtagta atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aacgagccac cctctcctgc agggccagtc
      181 agagtattgg cagcacctta gcctggtacc agcagaaacc tgggcaggct cccaagctcc
      241 tcatctttgg tgcatccagc agggccaccg acatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga atttactctc accatcagca gcctggagtc tgtagatgtt ggagtttatt
      361 actgtcagca ggattatagc tggcctctca ctttcggcgg agggaccaag gtggagatga
      421 gacgag
//
LOCUS       KCVT01008071             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:10638:14360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008071
VERSION     KCVT01008071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10638:14360"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..397
                     /gene="IGKV2-82"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85596.1"
                     /translation="CMQGAQFPLTF"
     J_segment       400..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           85 a          119 c          111 g          101 t
ORIGIN      
        1 acatggggga tcaggactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tggggctgtt agtgctctgg ctccctggat ccagtgggga cattgtgatg acacagactc
      121 cactctccct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcccgca caaagatgga aacacatatt tgtattggta cctgcagagg ccgggccagt
      241 ctccacagct cctgatatat tttgcttcat accgggcctc tggagtccca gacaggttca
      301 gtggaagtgg gtcgggcact gatttcacac tacgaatcag tagggtggaa gctgaggata
      361 ttggagttta tttttgcatg caaggagcac agtttccact cactttcggc cccggg
//
LOCUS       KCVT01008072             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:17004:15680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008072
VERSION     KCVT01008072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17004:15680"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85597.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactgag
      181 gatattcgca gttacttggc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008073             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:17750:9594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008073
VERSION     KCVT01008073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17750:9594"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..397
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85598.1"
                     /translation="CMQSTKDPLTF"
     J_segment       399..434
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          101 a          123 c          107 g          106 t
ORIGIN      
        1 acatggggat caggactcct cagttcatct tctcacgatg agactccctg ctcagctcct
       61 cgggctgttg atgctctggg tccctggatc cagtggcgat attttgatga cccagactcc
      121 actctcgctg cccgtcaccc ctggagagcc ggcctccatc tcctgcaggt ctagtcaaag
      181 ccttctgcat agtaatggat acacctattt gcattggtac ctgcagaagc caggccagtc
      241 tccacgtctc ctgatctata aagttaccaa tcgggaatct ggggtcccag acaggttcag
      301 cggcagtggg tcaggcatag atttcacact gaaaatcagc agggtggagc ctgaggatgt
      361 tggtatttat tactgcatgc aaagtacaaa agatcccctc actttcggcc ccgggaccaa
      421 actggatatc aaacgag
//
LOCUS       KCVT01008074             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:18607:14779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008074
VERSION     KCVT01008074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18607:14779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85599.1"
                     /translation="CAQSTKDPRTF"
     J_segment       400..435
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT          103 a          117 c          117 g          101 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctgatt ccagtgggga tattgtgatg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gtcttctgca tagtaatgga aacacttatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gtggcagtgg gtcaggcaca gaattcacac tgaaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcgcg caaagtacaa aagatccccg gacgttcggc caagggacca
      421 aggtggaaat caaacgag
//
LOCUS       KCVT01008075             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:13371:14325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008075
VERSION     KCVT01008075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13371:14325"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85600.1"
                     /translation="CQQYNSDPYTF"
     J_segment       384..421
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          108 a          115 c          107 g           94 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgccg ggcgagtcag
      181 ggcattagaa gttatttagc gtggtatcag cagaaaccag gaaaagcccc gaaggccttg
      241 atctattacg catccatttt agaaagtgcg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagtctg acgattttgc agtttattac
      361 tgtcaacagt ataacagtga cccgtacact tttggcccgg ggaccaaagt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008076             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:18470:9536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008076
VERSION     KCVT01008076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18470:9536"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85601.1"
                     /translation="CMQALDFPYSF"
     J_segment       402..438
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          117 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag aagccaggcc
      241 agtctccaca gctcttgatt tttgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actaatttca cactgaaaat cagcagtgtg gaggctgagg
      361 atgttggggt ctattactgc atgcaagctc tagactttcc ttacagtttt ggtcagggga
      421 ccacagtgga gattaaacga g
//
LOCUS       KCVT01008077             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:14532:5513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008077
VERSION     KCVT01008077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14532:5513"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85602.1"
                     /translation="CMQALEFPLTF"
     J_segment       404..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtggaga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaatacct atttggaatg gcaccggcag atgccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagataggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctgacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008078             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:20543:4311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008078
VERSION     KCVT01008078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20543:4311"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85603.1"
                     /translation="CMQGLEFPPTF"
     J_segment       406..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           94 a          125 c          120 g          104 t
ORIGIN      
        1 acatggggct gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctaatgctct ggctccctgg atccagtggc gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atctcctgca ggtctagtca
      181 gagcctcttg gatagtggtg atggaaacac ctatttggaa tggttcctcc agaggccagg
      241 ccagtctcca cacctcttga tttatggggc ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc agtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 ggatgttggg gtttattact gcatgcaagg tctagagttt cctccgacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01008079             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:11304:5155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008079
VERSION     KCVT01008079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11304:5155"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85604.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          116 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca ttcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaggcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacaat atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008080             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:8662:3454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008080
VERSION     KCVT01008080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8662:3454"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..437
                     /note="immunoglobulin light chain variable region"
     V_region        99..437
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85605.1"
                     /translation="CMQSLEFPITF"
     J_segment       403..437
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>441
                     /gene="IGKC"
BASE COUNT           98 a          122 c          116 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcccc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gactcttgga tagtgagggt ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaatctc tagagtttcc aatcactttc ggccccggga
      421 ccaaactgga tatcaaaaga g
//
LOCUS       KCVT01008081             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6598:9969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008081
VERSION     KCVT01008081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6598:9969"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85606.1"
                     /translation="CQQYDSFPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          106 a          116 c          101 g          100 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acgttagcag ttatttaaac tggtatcagc agaaaccggg gaaagcccct aaactcctga
      241 tctattatac aaatcgtttg gaaactgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt ctctctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta tgatagtttt ccattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01008082             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22157:4819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008082
VERSION     KCVT01008082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22157:4819"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85607.1"
                     /translation="CMQALEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc catacgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agtagagtgg aggctgagga
      361 tgttgggatt tattactgca tgcaagctct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01008083             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13672:3301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008083
VERSION     KCVT01008083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13672:3301"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85608.1"
                     /translation="CQQHNGYPPTF"
     J_segment       391..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          108 a          120 c          110 g           90 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacacagtc accatcactt gtcggacaag
      181 tcagggcatt accaatgatt tagcctggta tcagcagaga ccagggaaag ccccgaagcc
      241 cctgatctat tacgcatcca atttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttattgtcaa cagcataatg gataccctcc gacgttcggc caagggacca gggtggaaat
      421 caaacgag
//
LOCUS       KCVT01008084             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:11846:12935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008084
VERSION     KCVT01008084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11846:12935"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..382
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85609.1"
                     /translation="CQQHDDSPRTF"
     J_segment       384..419
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          109 a          118 c          107 g           88 t
ORIGIN      
        1 acatgggggt cagtctcaga caggacacag catggacacg agggtccccg ctcagctcct
       61 ggggctcctg ttgctctggc tcccaggtgc cagatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgcacag ccagccacga
      181 tataaataac tggttggcct ggtatcaaca gaaaccagga aaagccccta agctcctgat
      241 ctatagggca tccaatttgg aaacaggggt cccatcgagg ttcagtggaa gtggatctgg
      301 gacagatttc actctcagca tcagcagcct gcagcctgaa gatttcgcaa catatttctg
      361 tcaacagcat gatgattccc ctcggacgtt cggccaaggg accaaggtgg aaatcaaacg
      421 ag
//
LOCUS       KCVT01008085             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:24580:8881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008085
VERSION     KCVT01008085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24580:8881"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85610.1"
                     /translation="CQQYDSDPYSF"
     J_segment       381..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          115 c          110 g           96 t
ORIGIN      
        1 acatggggtc agacccagtc aggacacagc ttggacatga gggtccccgc tcagctccta
       61 ggactcctgc tgctctgtct cccaggtgcc agatgtgaca tccagatgac ccagtctcca
      121 tcctccctgt ctgcttctgt aggagacaga gtcaccatca cttgtcgggc gagtcagggc
      181 attagcagtt atttagcgtg gtatcagcag aagccaggga aagccccgaa gcccttgatc
      241 tatttcgcat ccattttgga aagtggcgtc ccatcaaggt tcagcggcag tggatctggg
      301 acagaattca ctctcgccat cagcagcctg cagcctgaag attttgcaac ttattactgt
      361 caacagtatg acagtgaccc gtacagtttt ggccagggga ccaaagtgga gatcaaacga
      421 g
//
LOCUS       KCVT01008086             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:12846:4496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008086
VERSION     KCVT01008086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12846:4496"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85611.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          106 a          115 c          110 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc aacagaaacc agggaaagcc ccgaggccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagtc tgaagatttt gcaacttatt
      361 actgtcaaca atatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008087             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:20992:14160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008087
VERSION     KCVT01008087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20992:14160"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85612.1"
                     /translation="CQQYNSDPYTF"
     J_segment       382..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          113 c          111 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccaggtga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattagaagt tatttagcgt ggtatcagct gagaccaggg aaagccccga aggccttaat
      241 ctattacgcg accattttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgag gattttgcaa cttatttctg
      361 tcaacagtat aacagtgacc cgtacacttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01008088             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:23713:4425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008088
VERSION     KCVT01008088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23713:4425"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85613.1"
                     /translation="CMQALEFPRTF"
     J_segment       403..434
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           96 a          123 c          118 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctgtat ccagtggtga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgcggat ggaaacacct atttggactg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggtct ccgaccgggc ctctagagtc ccagacaggt
      301 tcagtggcag tggctcagac actgatttca cactgaaaat cagcagagtg gaggctgaag
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tcggacgttc ggccagggga
      421 ccaaggtgga aatcgaacga g
//
LOCUS       KCVT01008089             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:23524:18922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008089
VERSION     KCVT01008089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23524:18922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <358..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85614.1"
                     /translation="CQQGYDYPLTF"
     J_segment       382..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>421
                     /gene="IGKC"
BASE COUNT          100 a          113 c          112 g           96 t
ORIGIN      
        1 acggggagtc agtctcagtc aggacacagc atggacatga gggtccccgc tcagctcctt
       61 gggctcctgc tgctctggct cccaggtgcc agatgtgaca tccagatgac gcagtctcca
      121 tcctccctgt ccgcatctgt aggagacaca gtcacgatca cttgccaggc gagtcaaggc
      181 attggcaata atttaaattg gtatcagcag aaaccaggga aagcccctaa actcctgatc
      241 tatagggcat ccagtttgca aagtgggatt ccctctcggt tcagcggcgg tgggtcttgg
      301 acggaataca gtctcaccat cagcagcctg cagcctgaag attttggcac ttattactgt
      361 caacagggtt atgattaccc tctcactttc ggtggaggga ccaaggtgga gatcaaacga
      421 g
//
LOCUS       KCVT01008090             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:14842:23295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008090
VERSION     KCVT01008090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14842:23295"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85615.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           98 a          126 c          114 g           88 t
ORIGIN      
        1 acatgggggg ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01008091             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:21552:2748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008091
VERSION     KCVT01008091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21552:2748"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..429
                     /note="immunoglobulin light chain variable region"
     V_region        93..429
     V_segment       93..391
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85616.1"
                     /translation="CGQGTHLPLTF"
     J_segment       392..429
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>432
                     /gene="IGKC"
BASE COUNT           95 a          120 c          120 g           97 t
ORIGIN      
        1 acatgggact gatcaggact cctcagttca ccatgaggct ccctgctcag ctcctggggc
       61 tgctattgct ctgcgtcccc ggatccagtg gggatgttgt gctgactcag tctccactct
      121 ccctgcccat cacccctgga cagccggcct ccatctcctg caggtctagt caaagccttg
      181 tatatagcac tggaaacaca tacttgagtt ggtatcaaca gaagccaggc caacctccga
      241 ggcgcctaat ttatgaggtt tcttaccggg actctggggt cccagacaga ttcagcggca
      301 gtggggcagg gacagatttc acactgaaaa tcagcagagt ggaggctgag gatgttgggg
      361 tttattactg cgggcaaggt acacaccttc cgctcacttt cggcggaggg accaaggtgg
      421 agatcaaacg ag
//
LOCUS       KCVT01008092             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:6545:15133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008092
VERSION     KCVT01008092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6545:15133"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85617.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          121 c          120 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacact gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tactgaggat ggaaacacct atttggaatg gtacctacag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008093             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:19672:6956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008093
VERSION     KCVT01008093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19672:6956"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85618.1"
                     /translation="CQQDFGWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          118 c          116 g           90 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccat tctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agactgttgg cagcgcctta gcctggtacc aacagaaacc tgggcagact cacaaactcc
      241 tcatttatgg tgcatccagc agggccaccg gcatcccaga caggttcagt ggcagtgggt
      301 ctggaacaga gttcactctc actatcagta gtccggagcc tgaggatgtt ggagtttatt
      361 actgtcagca ggattttggc tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01008094             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:21565:12783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008094
VERSION     KCVT01008094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21565:12783"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85619.1"
                     /translation="CQQYNSDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          117 c          109 g           92 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa cccccgcagc ccttgatcta
      241 ttacgcgtcc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt atttctgtca
      361 acagtataac agtgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01008095             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:22305:6687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008095
VERSION     KCVT01008095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22305:6687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85620.1"
                     /translation="CMQALEFPLTF"
     J_segment       406..442
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           96 a          120 c          122 g          107 t
ORIGIN      
        1 acatgggtga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct gggtccagtg gggacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatggtga ggatggaaac acctatttgg aatggtacct gcagaagcca
      241 ggccagtctc cacagctctt gatttatgag gtttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg ggatttatta ctgcatgcaa gctctagagt ttcctctcac tttcggtgga
      421 gggaccaagg tggagatcaa acgag
//
LOCUS       KCVT01008096             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:16857:8933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008096
VERSION     KCVT01008096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16857:8933"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..373
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85621.1"
                     /translation="CQQGYTYLYSF"
     J_segment       381..419
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          104 a          116 c          104 g           98 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 catcctccct gtccgcatct gtaggagaca cagtcaccat cacttgccag gcgagtcaag
      181 ccattgccaa taatttaaat tggtatcagc agaaaccagg aaaagcccct aaagtcctga
      241 tctatagggc atccagtttg caaagtggga ttccctctcg gttcagcgca gtggatctgg
      301 gacggatttc actctcacca tcagcagcct gcagcctgaa gattttgcca cttattactg
      361 tcaacagggt tatacttacc tgtacagttt tggccagggg accaaagtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01008097             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:8735:16226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008097
VERSION     KCVT01008097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8735:16226"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85622.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctctaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008098             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:12848:12637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008098
VERSION     KCVT01008098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12848:12637"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..433
                     /note="immunoglobulin light chain variable region"
     V_region        97..433
     V_segment       97..398
                     /gene="IGKV4-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85623.1"
                     /translation="CQQFYSTPTF"
     J_segment       399..433
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          106 a          114 c          117 g           99 t
ORIGIN      
        1 acatgggggc tacaacaggc aggcaggggc agcaagatgg tgtcacagac ccaagtcttc
       61 atttccctgt tgctctggat ctctggtgcc tgtggggaca ttgtgatgac ccagtcgcca
      121 gactccctgg ctgtgtctct gggagagagg gtcaccatca actgcaagtc cacccagagt
      181 cttttataca gcttcaacaa taggaactac ttagcctggt accagcagaa accaggacag
      241 gctcctaaga tgctcattta ctgggcatct acccgggaat ccggggtccc taaccgattc
      301 agtggcagtg gatctgggtc agatttcact ctcaccatca gtggcctaca ggctgaagat
      361 gtggcagtgt attactgtca gcagttttat agcactccga cgttcggcca agggaccaac
      421 gtggaaatca aacgag
//
LOCUS       KCVT01008099             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:20301:13846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008099
VERSION     KCVT01008099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20301:13846"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85624.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          105 a          115 c          109 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcaa cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccatttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008100             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:16532:13289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008100
VERSION     KCVT01008100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16532:13289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85625.1"
                     /translation="CQQYNSLPWTF"
     J_segment       379..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          111 a          107 c          106 g           95 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagttattat ttaaattggt atcaacagaa accggggaaa gcccctaagg tcctgatcta
      241 ttatacaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attactgtca
      361 acaatataat agtttaccgt ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01008101             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:21655:19794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008101
VERSION     KCVT01008101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21655:19794"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85626.1"
                     /translation="CHQHNSFPYSF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT           98 a          108 c          106 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagaa acagtcaccg tcacttgtcg ggcaagtcgg ggcgttagta atgatttagc
      181 ctggtatcag cagaaaccag ggaaagcccc gaggcccctg atctattatg catccaattt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagatt tcactctcac
      301 aatcagcagc ctgcagcctg aagattttgc aacttattac tgtcaccaac ataatagttt
      361 cccgtacagt tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01008102             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:23240:12801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008102
VERSION     KCVT01008102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23240:12801"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    148..348
                     /note="immunoglobulin light chain variable region"
     V_region        148..348
     V_segment       148..310
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <288..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85627.1"
                     /translation="CMQALEFPWTF"
     J_segment       311..348
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>351
                     /gene="IGKC"
BASE COUNT           78 a           97 c           94 g           82 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggctc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc agtctccaca actcttgatt tatgaggttt
      181 ccaaccgggc ctctggagtc ccagacaggt tcagtggcag tgggtcagac actgatttca
      241 cactgaaaat cagcagagtg gaggctgagg atgttggggt ttattactgc atgcaagctc
      301 tagaatttcc gtggacgttc ggccaaggga ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008103             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17718:7586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008103
VERSION     KCVT01008103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17718:7586"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..377
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85628.1"
                     /translation="CQQGYSYPWTF"
     J_segment       383..420
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           99 a          117 c          111 g           96 t
ORIGIN      
        1 acatggggag tcagtctcag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 ttgggctcct gctgctctgg ctcccaggtg ccagatgtga catccagatg acgcagtctc
      121 cctcctccct gtccgcatct gtaggagacg cagtcacgat cacttgccag gcgagtcaag
      181 gcattggcaa taatttaaat tggtttcagc agaaaccagg gaaagcccct aaactcctga
      241 tctataagac atccagtttg caaagtggga ttccctctcg gttcagcggc agtggatctg
      301 gggcggattt cactctcacc atcaccagcc tgcagcctga agattttgcc acttattact
      361 gtcaacaggg ttatagttac ccgtggacgt tcggccaagg ggccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008104             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:22551:9764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008104
VERSION     KCVT01008104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22551:9764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..426
                     /note="immunoglobulin light chain variable region"
     V_region        90..426
     V_segment       90..388
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85629.1"
                     /translation="CGQGTHLPLTF"
     J_segment       389..426
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT           94 a          119 c          120 g           96 t
ORIGIN      
        1 acatggggat caggactcct cagttcacca tgaggctccc tgctcagctc ctggggctgc
       61 tattgctctg cgtccccgga tccagtgggg atgttgtgct gactcagtct ccactctccc
      121 tgcccatcac ccctggacag ccggcctcca tctcctgcag gtctagtcaa agccttgtat
      181 atagcactgg aaacacatac ttgagttggt atcaacagaa gccaggccaa cctccgaggc
      241 gcctaattta tgaggtttct taccgggact ctggggtccc agacagattc agcggcagtg
      301 gggcagggac agatttcaca ctgaaaatca gcagagtgga ggctgaggat gttggggttt
      361 attactgcgg gcaaggtaca caccttccgc tcactttcgg cggagggacc aaggtggaga
      421 tcaaacgag
//
LOCUS       KCVT01008105             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:14635:15243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008105
VERSION     KCVT01008105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14635:15243"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85630.1"
                     /translation="CEQYNSLPYTF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          106 a          106 c           97 g           95 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgcttc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag gacattaaca tttatttaaa
      181 ttggtatcac cagaaaccgg ggaaagcccc taagctcctg atctattata caaaccgttt
      241 ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcactctcac
      301 catcagcagc ctgcaacctg aagattttgc aacttattac tgtgaacaat acaatagttt
      361 accgtacact tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01008106             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:24327:13931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008106
VERSION     KCVT01008106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24327:13931"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..435
                     /note="immunoglobulin light chain variable region"
     V_region        99..435
     V_segment       99..398
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85631.1"
                     /translation="CMQSTKDPLTF"
     J_segment       400..435
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>438
                     /gene="IGKC"
BASE COUNT           99 a          124 c          111 g          104 t
ORIGIN      
        1 acatggggga tcaggactcc tcagttcatc ttctcacgat gagactccct gctcagctcc
       61 tcgggctgtt gatgctctgg gtccctggat ccagtggcga tattttgctg acccagactc
      121 cactctcgct gcccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 gccttctgca aagtaatgga tacacctatt tgcattggta cctgcagaag ccaggccagt
      241 ctccacggct cctgatctat aaagttacca atcgggaatc tggggtccca gacaggttca
      301 gcggcagtgg gtcaggcata gatttcacac tggaaatcag cagggtggag cctgaggatg
      361 ttggtgttta ttactgcatg caaagtacaa aagatcccct cactttcggc cccgggacca
      421 aactggatat caaacgag
//
LOCUS       KCVT01008107             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:11477:13972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008107
VERSION     KCVT01008107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11477:13972"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85632.1"
                     /translation="CQQYNSLPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          104 a          108 c          110 g           97 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg cgctggctcc caggtgccag atgtgacatt gagatgaccc agtctccatc
      121 ctccctgtct gcttctgtag gagacagagt caccatcact tgccgggcaa gtcagggcgt
      181 taacgtttat ttaaattggt atcagcagaa accggggaaa gcccctaagc ccctgatctt
      241 ttatgcaaac cgtttggaac gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaagat tttgcaagtt attattgtca
      361 acagtataat agtttaccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01008108             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:19102:14289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008108
VERSION     KCVT01008108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19102:14289"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85633.1"
                     /translation="CLQFKTYPNSF"
     J_segment       381..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT           97 a          117 c          104 g          101 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcatctgtag gagacactgt caccatctct tgccgggcaa gtcagggtat
      181 tagcagttct ttaagttggt ttcagcagaa accagggaaa gcccctcagc tcctcatcta
      241 tgctacatcc agtttggccg gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattctct ctcaccatca ccagcctgca gcctgaagat tttgcaactt atttctgtct
      361 gcagtttaaa acttacccga acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01008109             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:10377:4066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008109
VERSION     KCVT01008109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10377:4066"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..363
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85634.1"
                     /translation="CLQGYIDPYSF"
     J_segment       378..415
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>418
                     /gene="IGKC"
BASE COUNT           98 a          112 c          110 g           98 t
ORIGIN      
        1 acatggggga accactcagg acacagcatg gacatgaggg tccccgctca gctcctgggg
       61 ctccttctgc tctggctccc aggtgccaga tgtgacttcc agatgaccca gtctccatct
      121 tccctgtctg catcggtcgg agacagagtc accatcactt gccgggcaag tcaggacatt
      181 agcgattttt taagttggta tcagcagaaa ccaggaaaac ctcctaagcg cctgatttat
      241 gctgcatcca gtttgcaaag tggggtcccg tcaaggttca gcggcagtgg atctgggaca
      301 gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcggctta ttactgtcta
      361 cagggttata ttgacccgta cagttttggc caggggacca aagtggagat caaacgag
//
LOCUS       KCVT01008110             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21918:10095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008110
VERSION     KCVT01008110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21918:10095"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..434
                     /note="immunoglobulin light chain variable region"
     V_region        99..434
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85635.1"
                     /translation="CMQYTHMPLTF"
     J_segment       401..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>441
                     /gene="IGKC"
BASE COUNT           98 a          120 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaagctccct gctcagctcc
       61 tggggctgct gatgctctgg ctctctggat ccagtgggga tattgtgatg acccagactc
      121 cactctccct gtccgtcacc cctggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga cagtgaggat ggaaacacct atttggattg gtacctgcaa aagccgggcc
      241 agtcgccaca gcccttgatt tatgaggttt ccaatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggaat ttattactgc atgcaatata cacacatgcc gctcactttc ggcggaggga
      421 ccaaggtgga gatcgaacga g
//
LOCUS       KCVT01008111             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:13265:8759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008111
VERSION     KCVT01008111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13265:8759"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..364
                     /note="immunoglobulin light chain variable region"
     V_region        87..364
     V_segment       87..322
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85636.1"
                     /translation="CQQYDSDSLTF"
     J_segment       327..364
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>367
                     /gene="IGKC"
BASE COUNT           90 a           97 c          100 g           80 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccagga gacagagtca ccatcacttg tcgggcgact
      121 caggacattc gcagttattt agcgtggtat cagcagaaac cagggaaagc cccgaggccc
      181 ttgatctatt acgcgtccac tttggaaagt ggggtcccat caaggttcag cggcagtgga
      241 tctgggacag atttcactct caccatcagc agcctgcagc ctgaagattt tgcaacttat
      301 tactgtcaac aatatgacag tgattcgctc actttcggtg gagggaccaa ggtggaggtc
      361 aaacgag
//
LOCUS       KCVT01008112             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:4393:16525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008112
VERSION     KCVT01008112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4393:16525"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85637.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          101 a          125 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtctatt
      361 tttgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggatatca
      421 aacgag
//
LOCUS       KCVT01008113             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:13045:20368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008113
VERSION     KCVT01008113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13045:20368"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85638.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          126 c          112 g           84 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctcccctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008114             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:4868:10741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008114
VERSION     KCVT01008114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4868:10741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..441
                     /note="immunoglobulin light chain variable region"
     V_region        102..441
     V_segment       102..403
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <381..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85639.1"
                     /translation="CMQALEFPWTF"
     J_segment       404..441
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>444
                     /gene="IGKC"
BASE COUNT          101 a          119 c          121 g          103 t
ORIGIN      
        1 acatggggac tgatcacgac tcctcaggtc accttctcac aatgaggctc cctgctcagc
       61 tcctgggact gctaatgctc tggctccctg gatccagtgg ggacattgtg atgacccaga
      121 ctccagtctc cctgcccgtc acccttagag agccggccac catctcctgc aggtctagtc
      181 agagcctctt ggatagtgag gatggaaaca cctatttgga atggtaccta cagaggccag
      241 gccagtctcc acagctctta atttatgagg tttcctaccg ggcctctgga gtcccagaca
      301 ggttcagtgg cagtgggtca gacactgatt tcacactgaa aatcagcaga gtggaggctg
      361 aggatgttgg ggtttattac tgcatgcaag ctctagagtt tccgtggacg ttcggccaag
      421 ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01008115             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:20260:17678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008115
VERSION     KCVT01008115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20260:17678"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..380
                     /gene="IGKV1-26"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85640.1"
                     /translation="CQQGDSYPRTF"
     J_segment       382..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          105 a          111 c          112 g           92 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat tcagatgtcc cagtctcctt
      121 cctccctgtc tgcatctgtg ggagacagag tcaccatcac ttgccgggca agtcaggaca
      181 ttagagatta tttaaattgg tatcagcagc aaccggggaa agcccctaaa ctcctgatgt
      241 attatgcaaa cagtctggca agtggagtcc catcaaggtt cagcggcagt ggatctggga
      301 cagaattcag tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagggtga cagttatcct cggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01008116             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:22337:6807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008116
VERSION     KCVT01008116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22337:6807"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85641.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          117 c          110 g           94 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctcctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagcc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008117             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:22210:22791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008117
VERSION     KCVT01008117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22210:22791"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    167..309
                     /note="immunoglobulin light chain variable region"
     V_region        167..309
     V_segment       167..271
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <249..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85642.1"
                     /translation="CMQGLEFPITF"
     J_segment       274..309
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>312
                     /gene="IGKC"
BASE COUNT           64 a           91 c           85 g           72 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg ttcagtggca
      181 gtgggtcaga cgctgatttc acactgcgaa tcagcagagt ggaggctgag gatgttgggg
      241 tttattactg catgcaaggt ctagagtttc caatcacttt cggccccggg accaaactgg
      301 agatcaaacg ag
//
LOCUS       KCVT01008118             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:21885:2005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008118
VERSION     KCVT01008118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21885:2005"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85643.1"
                     /translation="CQQYDTDPRTF"
     J_segment       382..416
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          101 a          116 c          111 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctagg
       61 actcctgctg ctctgtctcc caggtgccaa atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgtcgggcga gtcagggcat
      181 tcgcagttat ttagcgtggt atcagcagaa accagggaaa gccccgaagc ccttgatcta
      241 ttacgcgtcc attttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agagttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtca
      361 acagtatgac actgacccgc gcactttcgg tggagggacc aaggtggaga tcaaacgag
//
LOCUS       KCVT01008119             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5147:12383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008119
VERSION     KCVT01008119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5147:12383"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85644.1"
                     /translation="CQQYNSLPYIF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          111 c          106 g           99 t
ORIGIN      
        1 acatgggggg tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcgt ttttttaaat tggtatcagc agaaaccggg gaaagcccct aaacccctga
      241 tctattatgc aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacattt ttggccaggg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008120             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13742:15305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008120
VERSION     KCVT01008120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13742:15305"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..370
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85645.1"
                     /translation="CQQHNGYPPTF"
     J_segment       383..417
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          108 a          118 c          105 g           89 t
ORIGIN      
        1 acatggggga gaaccactca ggacacagca tggacatgag ggtccccgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatctgta ggagacacag tcaccatcac ttgtcgggca agtcagggca
      181 ttacgaatga tttagcctgg tatcaacaga aaccaggtaa agccccgaag cccctgatct
      241 attacgcatc caatttggaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttttgcaact tattattgtc
      361 aacaacataa tggataccct ccgacgttcg gccaagggac cagggtggaa atcaaacgag
//
LOCUS       KCVT01008121             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9708:2573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008121
VERSION     KCVT01008121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9708:2573"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85646.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          122 c          118 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggggcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008122             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:22127:7102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008122
VERSION     KCVT01008122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22127:7102"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..379
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85647.1"
                     /translation="CQQYDSDSLTF"
     J_segment       384..421
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          104 a          117 c          109 g           94 t
ORIGIN      
        1 acatggggca gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgtcg ggcgactcag
      181 gacattcgca gttatttagc gtggtatcag cagaaaccag ggaaagcccc gaagcccttg
      241 atctattacg cgtccacttt ggaaagtggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagaat tcactctcac catcagcagc ctgcagcctg aagattttgc aacttattac
      361 tgtcaacagt atgacagtga ttcgctcact ttcggtggag ggaccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008123             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18464:14701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008123
VERSION     KCVT01008123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18464:14701"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85648.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          123 g          102 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaagttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagttccc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008124             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:13289:20916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008124
VERSION     KCVT01008124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13289:20916"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85649.1"
                     /translation="CIQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT          100 a          119 c          119 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atacaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008125             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:15505:3836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008125
VERSION     KCVT01008125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15505:3836"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85650.1"
                     /translation="CMQGLEFPITF"
     J_segment       403..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          125 c          115 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgatgttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgtcggggt ttattactgc atgcaaggtc tagagtttcc aatcactttc ggccccggga
      421 cccgactgga tatcaaacga g
//
LOCUS       KCVT01008126             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14038:8857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008126
VERSION     KCVT01008126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14038:8857"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..442
                     /note="immunoglobulin light chain variable region"
     V_region        103..442
     V_segment       103..405
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <382..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85651.1"
                     /translation="CMQGLEFPPTF"
     J_segment       408..442
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>445
                     /gene="IGKC"
BASE COUNT           95 a          125 c          121 g          104 t
ORIGIN      
        1 acatggggga ctgatcacga ctcctcaggt caccttctca caatgaggct ccctgctcag
       61 ctcctgggac tgctaatgct ctggctccct ggatccagtg gcgacattgt gatgacccag
      121 actccactct ccctgcccgt cacccttgga gagccggcct ccatctcctg caggtctagt
      181 cagagcctct tggatagtgg tgatggaaac acctatttgg aatggttcct ccagaggcca
      241 ggccagtctc cacacctctt gatttatggg gcttccaacc gggcctctgg agtcccagac
      301 aggttcagtg gcagtgggtc agacactgat ttcacactga aaatcagcag agtggaggct
      361 gaggatgttg gggtttatta ctgcatgcaa ggtctagagt ttcctccgac gttcggccaa
      421 gggaccaagg tggaaatcaa acgag
//
LOCUS       KCVT01008127             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:11623:17463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008127
VERSION     KCVT01008127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11623:17463"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..370
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85652.1"
                     /translation="CLQGYTIPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          107 a          114 c          109 g           95 t
ORIGIN      
        1 acatgggggg agtcagaacc actcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc cttctgctct ggctcccagg tgccagatgt gacatccaga tgacccagtc
      121 tccatcttcc ctgtctgcat cggtaggaga cagagtcacc atcacttgcc ggacaagtca
      181 gggcattagc gattatttaa gttggtatca gcagaaacca ggaaaagctc ctaagcgcct
      241 gatccatgct gtatccagtt tggaaagtgg ggccccatca aggttcagcg gcagtggatc
      301 tgaaacagag ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtctacag ggttatacta tcccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01008128             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:16970:11808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008128
VERSION     KCVT01008128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16970:11808"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85653.1"
                     /translation="CVQALEFPWTF"
     J_segment       402..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          107 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccaatgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggatt ggtacctgca gaagccaggc
      241 cagtctccac aactcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtctga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg cgttcaagct ctagagtttc cgtggacttt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01008129             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:20526:9209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008129
VERSION     KCVT01008129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20526:9209"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85654.1"
                     /translation="CQQHDDSPRTF"
     J_segment       390..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          117 c          110 g           89 t
ORIGIN      
        1 acatgggggc aggagtcagt ctcagacagg acacagcatg gacacgaggg tccccgctca
       61 gctcctgggg ctcctgttgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gcacagccag
      181 tcaggatatt aataactggt tggcctggta tcaacagaaa ccaggaaaag cccctaaact
      241 cctgatctat agggcatcca atttggaaac aggggtccca tcgaggttcg gtggaagtgg
      301 atctgggaca gatttcactc tcaccattag cagcctgcag cctgaagata tcgcaacata
      361 ttactgtcaa cagcatgatg attcccctcg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01008130             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:13552:14779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008130
VERSION     KCVT01008130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13552:14779"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..364
                     /gene="IGKV1-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85655.1"
                     /translation="CLQGYIIPYNF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          109 c          109 g           99 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctccttctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ttccctgtct gcatcggtag gagacagagt caccatcact tgccgggcaa gtcaggacat
      181 tagcgatttt ttaagttggt atcagcagaa accaggaaaa cctcctaagc gcctgattta
      241 tgctgcatcc agtttggaaa gtggggtccc gtcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcggctt attattgtct
      361 acagggttat attatcccgt acaattttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01008131             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:17977:12574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008131
VERSION     KCVT01008131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17977:12574"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85656.1"
                     /translation="CQQNSNWPLTF"
     J_segment       386..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          101 a          124 c          115 g           85 t
ORIGIN      
        1 acatggggag gaactgctca gttaggaccc agagggaacc atggaagccc cagcacagct
       61 tctcttcctc ctgctgctct ggctcccaga taccaccgga gaaatagtgc tgacgcagtc
      121 tccagccacc ctgtctttgt ctccaggaga aagagccacc ctctcctgca gggccagtca
      181 gagtgtcagc agcagcttag cctggtacca gcagaaacct gggcaggctc ccagactcct
      241 catctatggt gcaaccaaca gggccactgg catcccaggc aggttcagtg gcagtgggtc
      301 tgggacagag ttcactctca ccatcagcag cctggagcct gaagatgttg tactttatta
      361 ttgtcagcag aacagtaact ggcctctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01008132             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:5546:8402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008132
VERSION     KCVT01008132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5546:8402"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85657.1"
                     /translation="CQQYDSDPFTF"
     J_segment       385..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          103 a          115 c          112 g           93 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtcagcat cacttgtcgg gcgagtcagg
      181 gcattcgcag ttatttagcg tggtatcagc agagaccagg gaaagccccg aagcccttga
      241 tctattacgc gtccactttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcagcctga agattttgca acttattact
      361 gtcaacagta tgacagtgac ccgttcactt tcggtggagg gaccaaggta gagatcaaac
      421 gag
//
LOCUS       KCVT01008133             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:24257:4585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008133
VERSION     KCVT01008133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24257:4585"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85658.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc cttagagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctacag atgccaggcc
      241 agtctccaca gctcttaatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008134             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:16752:18932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008134
VERSION     KCVT01008134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16752:18932"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..390
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85659.1"
                     /translation="CQQHDDSPRTF"
     J_segment       392..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          111 a          117 c          114 g           88 t
ORIGIN      
        1 acatgggggg gcaggagtca gtctcagaca ggacacagca tggacacgag ggtccccgct
       61 cagctcctgg ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc
      181 agtcaggata ttaacaactg gttggcctgg tatcaacaga aaccagggaa agcccctaag
      241 gtcctgatct atagggcatc cattttggaa acaggggtcc catcaaggtt cagtggaagt
      301 ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca
      361 tattactgtc aacagcatga tgattcccct cggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01008135             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:23062:11352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008135
VERSION     KCVT01008135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23062:11352"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85660.1"
                     /translation="CQQYNSLPLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          107 a          109 c          108 g           99 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tggggctcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcatct ctgggtgaca gagtcaccat cacttgccgg gcaagtcagg
      181 acattagcag atatttaaat tggtatcagc agaaaccggg gaaagcccct aagttcctga
      241 tctattatgt aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagcc tgcaacctga agattttgca acttattatt
      361 gtcaacagta taatagttta ccgctcactt tcggtggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008136             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:8208:4459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008136
VERSION     KCVT01008136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8208:4459"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..378
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85661.1"
                     /translation="CQQYDSDLFTF"
     J_segment       382..417
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          102 a          113 c          110 g           95 t
ORIGIN      
        1 acatggggga gacccagtca ggacacagca tggacatgag ggtccccgct cagctcctag
       61 gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc cagtctccat
      121 cctccctgtc tgcatttgta ggagacagag tcaccatcac ttgtcgggcg agtcagggca
      181 ttcgcagtta tttagcgtgg tatcagcaga aaccagggaa agccccgaag cccttgatct
      241 attacgcgtc cactttggaa agtggggtcc catcaaggtt cagcggcagt ggttctggga
      301 cagaattcac tctcaccatc aacagcctgc agcctgaaga ttttgcaact tattactgtc
      361 aacagtatga cagtgacctg ttcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01008137             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:19238:4176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008137
VERSION     KCVT01008137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19238:4176"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85662.1"
                     /translation="CQQHADSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          117 c          109 g           88 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagagcca gtcagggtat
      181 tagcaactgg ttggcctggt atcaacagag accagggaaa gcccctaagg tcctgattta
      241 taggacatcc aatttggaaa caggggtccc atcaaggttc agtggaaccg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat ttcgctacat attactgtca
      361 acagcatgct gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01008138             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:17928:13460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008138
VERSION     KCVT01008138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17928:13460"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..379
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85663.1"
                     /translation="CQQHDDSPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          108 a          116 c          106 g           89 t
ORIGIN      
        1 acatggggag tctcagacag gacacagcat ggacacgagg gtccccgctc agctcctggg
       61 gctcctgttg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcacagcca gtcagggtat
      181 taataactgg ttggcctggt atcaacagaa accaggaaaa gcccctaaac tccttatcta
      241 tagggcatcc aatttggaaa caggggtccc atcgaggttc ggtggaagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat atcgcaacat atttctgtca
      361 acagcatgat gattcccctc ggacgttcgg ccaagggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01008139             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:15195:16519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008139
VERSION     KCVT01008139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15195:16519"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    182..341
                     /note="immunoglobulin light chain variable region"
     V_region        182..341
     V_segment       182..303
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <281..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85664.1"
                     /translation="CIQALEFPWTF"
     J_segment       304..341
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>344
                     /gene="IGKC"
BASE COUNT           74 a          100 c           94 g           76 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cctctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctggc tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctctgga gtcccagaca ggttcagtgg cagtgggtca gacactgatt tcacactgaa
      241 aatcagcaga gtggaggctg aggatgttgg gacttattac tgcatccaag ctctagagtt
      301 tccgtggacg ttcggccaag ggaccaaggt ggaaatcaaa cgag
//
LOCUS       KCVT01008140             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:14517:4363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008140
VERSION     KCVT01008140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14517:4363"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85665.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT           99 a          127 c          113 g           87 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggcc cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01008141             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:11045:19615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008141
VERSION     KCVT01008141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11045:19615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85666.1"
                     /translation="CQQYDSDSLTF"
     J_segment       386..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          115 c          111 g           95 t
ORIGIN      
        1 acatggggag gagtcagacc cagtcaggac acagcatgga catgagggtc cccgctcagc
       61 tcctaggact cctgctgctc tgtctcccag gtgccaaatg tgacatccag atgacccagt
      121 ctccatcctc cctgtctgca tctgtaggag acagagtcac catcacttgt cgggcgactc
      181 aggacattcg cagttattta gcgtggtatc agcagaaacc agggaaagtc ccgaagccct
      241 tgatctatta cgcgtccact ttggaaagtg gggtcccatc aaggttcagc ggcagtggat
      301 ctgggacaga attcactctc accatcagca gcctgcagcc tgaagatttt gcaacttatt
      361 actgtcaaca gtatgacagt gattcgctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008142             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:13064:10922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008142
VERSION     KCVT01008142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13064:10922"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85667.1"
                     /translation="CQQYNSLPLTF"
     J_segment       382..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          108 a          109 c          108 g           97 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgccggg caagtcagga
      181 cattagcaga tatttaaatt ggtatcagca gaaaccgggg aaagccccta agttcctgat
      241 ctattatgta aaccgtttgg aaagcggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattattg
      361 tcaacagtat aatagtttac cgctcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01008143             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:9715:17877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008143
VERSION     KCVT01008143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9715:17877"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85668.1"
                     /translation="CQQHAYSPRTF"
     J_segment       386..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          106 a          119 c          111 g           88 t
ORIGIN      
        1 acatggggga gtcagtctca gacaggacac agcatggaca cgagggtccc cgctcagctc
       61 ctggggctcc tgttgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtcacca tcacttgcag agccagtcag
      181 ggtattagca actggttggc ctggtatcag cagagaccag ggaaagcccc taaggtcctg
      241 atctatagga catccaattt ggaaacaggg gtcccatcaa ggttcagtgg aaccggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc aacatattac
      361 tgtcaacagc atgcttattc ccctcggacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01008144             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:5738:15381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008144
VERSION     KCVT01008144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5738:15381"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85669.1"
                     /translation="CLQYKTYPYSF"
     J_segment       379..416
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          105 a          110 c          106 g           98 t
ORIGIN      
        1 acatggggag acacagtcag gacacagcat ggacatgagg gcccccgctc atctcctagg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgactc agtctccatc
      121 ttccctgtct gcttctgtag gagacactgt caccatcact tgccgggcaa gtcagggtat
      181 tgctggttat ttaaattggt ttcagaagaa accagggaaa gcccctaagc tcctgatcca
      241 agctgcatcc agtttggaaa gtggggtccc agcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt attactgtct
      361 acagtataaa acttatccgt acagttttgg ccaggggacc aaagtggaga tcaaacgag
//
LOCUS       KCVT01008145             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:17190:17056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008145
VERSION     KCVT01008145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17190:17056"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..384
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85670.1"
                     /translation="CEQYNSLPYTF"
     J_segment       385..422
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          112 a          110 c          104 g           99 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctggggctc ctgctgctct ggctcccagg tgccagatgt gacattcaga tgacccagtc
      121 tccatcctcc ctgtctgctt ctgtaggaga cagagtcacc atcacttgcc gggcaagtca
      181 ggacattaac atttatttaa attggtatca ccagaaaccg gggaaagccc ctaagctcct
      241 gatttattat acaaatcgtt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcaacct gaagattttg caacttatta
      361 ctgtgaacaa tacaatagtt taccgtacac ttttggccag gggaccaaag tggagatcaa
      421 acgag
//
LOCUS       KCVT01008146             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:6519:9278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008146
VERSION     KCVT01008146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6519:9278"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85671.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          117 c          122 g          107 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcact cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagaa actgatttca cactgaagat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008147             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2103:18346:3013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008147
VERSION     KCVT01008147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18346:3013"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85672.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          114 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtccttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag tagcagctta gcctggtacc aacaaagacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccacc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgacgatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008148             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:17123:11174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008148
VERSION     KCVT01008148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17123:11174"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85673.1"
                     /translation="CMQALEFPWTF"
     J_segment       402..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           97 a          119 c          122 g          103 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cagtctccct gcccgtcacc ctgggagagc cggcctccat ctcctgccgg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gcacctgcag aggccaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctatcgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac acagatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggtat ttattactgc atgcaagctc tagagtttcc ttggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008149             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:28529:9517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008149
VERSION     KCVT01008149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:28529:9517"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85674.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           94 a          119 c          123 g          106 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccactctccc tgcccgtcac ccttggggag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggtacctgca caagccaggc
      241 cagtctccag agctcttgat ttatgaggtt tccaagcggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagatt ggaggctgag
      361 gatgttgggc tttattactg tatgcaagct ctagagtttc ctctcacttt cggcggaggg
      421 accaaggtgg aggtcaaacg ag
//
LOCUS       KCVT01008150             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:2765:9369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008150
VERSION     KCVT01008150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:2765:9369"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85675.1"
                     /translation="CQQDFDWPTTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          125 c          113 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctacga cgttcggcca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01008151             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:6187:16593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008151
VERSION     KCVT01008151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6187:16593"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85676.1"
                     /translation="CQQYNSDPRTF"
     J_segment       385..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          117 c          111 g           91 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga agcccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat aacagtgacc cgcgcacttt cggtggaggg accaaggtgg agatcaaacg
      421 ag
//
LOCUS       KCVT01008152             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:11219:3878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008152
VERSION     KCVT01008152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11219:3878"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..357
                     /note="immunoglobulin light chain variable region"
     V_region        44..357
     V_segment       44..319
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <297..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85677.1"
                     /translation="CMQALEFPWTF"
     J_segment       320..357
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>360
                     /gene="IGKC"
BASE COUNT           86 a           92 c           99 g           83 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg cccgtcaccc
       61 ttagagagcc ggcctccatc tcctgcaggt ctagtcagag cctcttggat agtgaggatg
      121 gaaacaccta tttggaatgg tacctacaga ggccaggcca gtctccacag ctcttaattt
      181 atgaggtttc ctaccgggcc tctggagtcc cagacaggtt cagtggcagt gggtcagaca
      241 ctgatttcac actgaaaatc agcagagtgg aggctgagga tgttggggtt tattactgca
      301 tgcaagctct agagtttccg tggacgttcg gccaagggac caaggtggaa atcaaacgag
//
LOCUS       KCVT01008153             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:9455:3475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008153
VERSION     KCVT01008153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9455:3475"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85678.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagcgggga cattgtgatg acccagactc
      121 cactctccct gtccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tggtgaggat ggaaacacct acttggaatg gtatttccag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaagcggga ctctggagtc gcagacaggt
      301 tcagtggcag tgggtcaggc actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatcactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008154             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:21176:13669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008154
VERSION     KCVT01008154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21176:13669"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85679.1"
                     /translation="CHQYNNLPLTF"
     J_segment       389..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          110 a          115 c          106 g           97 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg cttctgtagg agacagagtc accatcactt gccgggcaag
      181 tcaggacatt aacatttatt taaattggta tcagcagaaa ccggggaaag cccctaagct
      241 cctgatctat tatgcaaatc gtttggaaac tggggtcccg tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcaa cagcctgcaa cccgaagatt ttgcaactta
      361 ttactgtcac cagtataata atttaccact cactttcggc ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01008155             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:20638:15239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008155
VERSION     KCVT01008155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20638:15239"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85680.1"
                     /translation="CMQALEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           96 a          118 c          121 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgctc atgctctggc tccctgtatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatg tcctgcaggt ctagtcagag
      181 tctcttggat agtgaggatg gaaacaccta tttggaatgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcggt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgatga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01008156             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:12323:2522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008156
VERSION     KCVT01008156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12323:2522"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85681.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          123 c          115 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccactgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaaa
      181 ggctcttgga tagtgaggat gaaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttatttctgc atgcaagctc tagagtttcc attcactttc ggccccggga
      421 ccaagctgga aatcaaacga g
//
LOCUS       KCVT01008157             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:8976:7912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008157
VERSION     KCVT01008157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8976:7912"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..409
                     /note="immunoglobulin light chain variable region"
     V_region        70..409
     V_segment       70..372
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85682.1"
                     /translation="CMQALEFPLTF"
     J_segment       375..409
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>412
                     /gene="IGKC"
BASE COUNT           92 a          108 c          115 g           97 t
ORIGIN      
        1 acatgggcaa tgaggctccc tgctcagctc ctgggactgc taatgctctg gctccctgga
       61 tccagtggag acattgtgat gacccagact ccactctccc tgcccgtcac ccttggagag
      121 ccggcctcca tctcctgtag gtctagtcag agcctcttgg atagtgagga tggaaatacc
      181 tatttggaat ggcaccggca gatgccaggc cagtctccac agctcttgat ttatgaggtt
      241 tccaaccggg cctctggagt cccagacagg ttcagtggca gtgggtcaga cactgatttc
      301 acactgaaaa tcagcagagt ggaggctgag gatgttgggg tttattactg catgcaagct
      361 ctagagtttc ctctgacgtt cggccaaggg accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01008158             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:6531:6757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008158
VERSION     KCVT01008158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6531:6757"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..413
                     /note="immunoglobulin light chain variable region"
     V_region        95..413
     V_segment       95..379
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85683.1"
                     /translation="CQEYNRLPRTF"
     J_segment       381..413
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>419
                     /gene="IGKC"
BASE COUNT          104 a          111 c          110 g           94 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtcagggcat
      181 tagtcaatat ttaaattggt atcagcagaa accggggaaa gcccctaggc tcctcatcta
      241 ttatgtaaac cgtttggaaa gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agaattcact ctcaccatca gcagcctgca acctgaggat tttgcaactt attactgtca
      361 ggagtataat cgtttacctc ggacgttcgg ccaagggacc aaggtggaaa tcagacgag
//
LOCUS       KCVT01008159             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:27265:12559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008159
VERSION     KCVT01008159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:27265:12559"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85684.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          105 a          125 c          111 g           85 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag caacagctta gcctggtacc aacaaaaacc tgggcagcct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg acatcccaga caggttcaga ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008160             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:7983:14662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008160
VERSION     KCVT01008160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7983:14662"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85685.1"
                     /translation="CMQALDFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          116 c          124 g          105 t
ORIGIN      
        1 acatggggga tcatgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ctagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccagggc
      241 agtctccaca actcttgatt tatgaggttt ccgaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tggactttcc gtggacgttc ggccaaggga
      421 ccaaggtgga agtcaaacga g
//
LOCUS       KCVT01008161             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2119:26769:9444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008161
VERSION     KCVT01008161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26769:9444"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85686.1"
                     /translation="CQQYNSDPYSF"
     J_segment       390..427
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          112 a          115 c          108 g           95 t
ORIGIN      
        1 acatggggat gcaggagtca gacccagtca ggacacagca tggacatgag ggtccccgct
       61 cagctcctag gactcctgct gctctgtctc ccaggtgcca aatgtgacat ccagatgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgccgggcg
      181 agtcagggca ttagaagtta tttagcgtgg tatcagcaga aaccaggaaa agccccgaag
      241 gccttgatct attacgcatc cattttagaa agtgcggtcc catcaaggtt cagcggcagt
      301 ggatctggga cagaattcac tctcaccatc agcagccttc agtctgacga ttttgcaact
      361 tattactgtc aacagtataa cagtgacccg tacagttttg gccaggggac caaagtggag
      421 atcaaacgag
//
LOCUS       KCVT01008162             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:25739:6839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008162
VERSION     KCVT01008162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25739:6839"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85687.1"
                     /translation="CQQYNSDPFTF"
     J_segment       384..421
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT          109 a          117 c          103 g           95 t
ORIGIN      
        1 acatggggga gtcagaccca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctaggactcc tgctgctctg tctcccaggt gccaaatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac agagtaacca tcacttgtcg ggcgagtcag
      181 gacataagaa gttatttagc gtggtatcag cagaaaccag gcaaagcccc gaagcccttg
      241 atctattacg catccgtttt ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct
      301 gggacagaat tcactctcac catcagcagt ctgcagcctg atgattttgc aacttattac
      361 tgtcaacagt ataacagtga cccattcact ttcggccccg ggaccaaact ggataccaaa
      421 cgag
//
LOCUS       KCVT01008163             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1101:13271:4988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008163
VERSION     KCVT01008163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13271:4988"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..417
                     /note="immunoglobulin light chain variable region"
     V_region        96..417
     V_segment       96..379
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85688.1"
                     /translation="CQHSYNTPYSF"
     J_segment       381..417
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>420
                     /gene="IGKC"
BASE COUNT          107 a          118 c          101 g           94 t
ORIGIN      
        1 acatggggca gtctcagtca ggacacagca tggacatgag ggcctctgct cagctcctag
       61 ggctcctgct gctctggctc ccaggcgcca gatgtgacat ccagatgacc cagtctccat
      121 tctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagggca agtcagaacg
      181 ttaacaacta tttacattgg tatcagcaga aaccagggaa agcccctaac ctcctgatct
      241 atgctgcatc cactttgcaa agtggggtcc catcaaggtt cagcggcagt ggatctggga
      301 cagacttcac tctcaccatc agcagcctgc agcctgaaga tgttgcaact tattactgtc
      361 agcatagtta taataccccc tacagttttg gccaggggac caaagtggag atcaaacgag
//
LOCUS       KCVT01008164             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1115:20570:13148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008164
VERSION     KCVT01008164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20570:13148"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85689.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           98 a          118 c          119 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaagcc
      241 agtctccaca gctcttgatt tatgaggttt ccatacgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagtagagtg gaggctgagg
      361 atgttgggat ttattactgc atgcaagctc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008165             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1103:18147:15085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008165
VERSION     KCVT01008165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18147:15085"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..436
                     /note="immunoglobulin light chain variable region"
     V_region        100..436
     V_segment       100..398
                     /gene="IGKV2-28"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85690.1"
                     /translation="CMQGLQTPYTF"
     J_segment       399..436
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           95 a          121 c          118 g          105 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcac cttgtcacaa tgaggctccc tgctcagctc
       61 ctggggctgc taatgctctg ggtctctgcc tccactggag atatcgtgat gacccagact
      121 ccactctcgc tgcccgtcac ccttggagag ccagcctcca tctcctgcag gtctagtcag
      181 agccttctga atagtaatgg atacagctat ttgagttggt acctgcagag gccaggccag
      241 tctccacatc tgctgatcta ttatggctct agtcgggcct ccggggtccc cgacaggttc
      301 agtggcagtg ggtcaggcac agattttaca ctgaaaatca ccagggtgga ggctgacgac
      361 gtaggggttt attactgcat gcaaggtcta caaactccgt acacttttgg ccaggggacc
      421 aaagtggaga tcaaacgag
//
LOCUS       KCVT01008166             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:6552:13560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008166
VERSION     KCVT01008166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6552:13560"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..380
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85691.1"
                     /translation="CQQYDSDSLTF"
     J_segment       385..422
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>425
                     /gene="IGKC"
BASE COUNT          104 a          116 c          111 g           94 t
ORIGIN      
        1 acatgggggg agtcagaccc agtcaggaca cagcatggac atgagggtcc ccgctcagct
       61 cctaggactc ctgctgctct gtctcccagg tgccaaatgt gacatccaga tgacccagtc
      121 tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc atcacttgtc gggcgactca
      181 ggacattcgc agttatttag cgtggtatca gcagaaacca gggaaagccc cgaggccctt
      241 gatctattac gcgtccactt tggaaagtgg ggtcccatca aggttcagcg gcagtggatc
      301 tgggacagaa ttcactctca ccatcagcag cctgcagcct gaagattttg caacttatta
      361 ctgtcaacaa tatgacagtg attcgctcac tttcggtgga gggaccaagg tggagatcaa
      421 acgag
//
LOCUS       KCVT01008167             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:21005:11971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008167
VERSION     KCVT01008167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21005:11971"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..373
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85692.1"
                     /translation="CQQHNSYPRTF"
     J_segment       381..416
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          103 a          118 c          106 g           92 t
ORIGIN      
        1 acatggggag aaccactcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacacagt caccatcact tgtcgggcaa gtcagggcgt
      181 tagcaattct ttagcctggt atcagcagaa accagggaaa gccccgaagc ccctgatcta
      241 ttacgcatcc attttggaaa gtggggtccc atcaagattc agcggcagtg gatctgggac
      301 agatttcact ctcaccatca gcagcctgca gcctgaagat tttgcaactt tttactgtca
      361 acagcataat agttatcctc ggacgttcgg ccaggggacc aaggtggaaa tcaaacgag
//
LOCUS       KCVT01008168             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:15018:8592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008168
VERSION     KCVT01008168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15018:8592"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85693.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          122 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct catgctctgg ctccctgtat ccagtgggga catcgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat gtcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcgg tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgatg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008169             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:18791:12395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008169
VERSION     KCVT01008169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18791:12395"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..389
                     /gene="IGKV1-66"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85694.1"
                     /translation="CQQHDNSPWTF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT          110 a          117 c          115 g           88 t
ORIGIN      
        1 acatgggggt gcaggagtca gtctcagaca ggacacagca tggacacgag ggtccccgct
       61 cagctcctgg ggctcctgtt gctctggctc ccaggtgcca gatgtgacat ccagatgacc
      121 cagtctccat cctccctgtc tgcatctgta ggagacagag tcaccatcac ttgcagagcc
      181 agtcagagta ttaacgactg gttggcctgg tatcaacaga gaccagggaa ggcccctaag
      241 ctcctgatct atagggcatc caatttggaa acaggggtcc catcaaggtt cagtggaagt
      301 ggatctggga cagatttcac tctcaccatc agcagcctgc agcctgaaga tatcgcaaca
      361 tattactgtc aacagcatga taattccccg tggacgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01008170             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:8087:7684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008170
VERSION     KCVT01008170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8087:7684"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..381
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85695.1"
                     /translation="CQQYYSDPFTF"
     J_segment       384..419
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>422
                     /gene="IGKC"
BASE COUNT          103 a          115 c          110 g           94 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 aggactcctg ctgctctgtc tcccaggtgc caaatgtgac atccagatga cccagtctcc
      121 atcctccctg tctgcatctg taggagacag agtcaccatc acttgtcggg cgagtcaggg
      181 cattcgcagt tatttagcgt ggtatcagca gaaaccaggg aaagccccga aggccttgat
      241 ctattacgcg tccactttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcagcctgaa gattttgcaa cttattactg
      361 tcaacagtat tacagtgacc cgttcacttt cggtggaggg accaaggtag agatcaaacg
      421 ag
//
LOCUS       KCVT01008171             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:13174:7015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008171
VERSION     KCVT01008171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13174:7015"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..426
                     /note="immunoglobulin light chain variable region"
     V_region        93..426
     V_segment       93..388
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85696.1"
                     /translation="CLQSKNSPWTF"
     J_segment       389..426
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>429
                     /gene="IGKC"
BASE COUNT          102 a          115 c          112 g          100 t
ORIGIN      
        1 acatggggca gcctctagtt cagctctcag aaatggggtc ctgggctcct ttcctgtgga
       61 tcctcctgct ctgtgctcca ggctgcaatg gggacattgt gctgacccag tctccagcct
      121 ctttggccgt gtctccaggg cagagggcca ccatcgtctg cagagccagt gagagtgtca
      181 atgtctttgg aataaacctc attcactggt atcagcagaa accaggacaa cctcctaaac
      241 ccctgattta ccaagcatcc aataaagaaa ctggggtccc agccaggttc agcggcagtg
      301 ggtctgggac cgatttcacc ctcacaatta atcctgtgga agctgacgat gctgcagatt
      361 attactgtct gcagagtaag aattctccgt ggacgtttgg ccaagggacc aaggtggaaa
      421 tcaaacgag
//
LOCUS       KCVT01008172             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:21774:12462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008172
VERSION     KCVT01008172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21774:12462"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85697.1"
                     /translation="CQQYNSDPFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          109 a          116 c          103 g           95 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 taggactcct gctgctctgt ctcccaggtg ccaaatgtga catccagatg acccagtctc
      121 catcctccct gtctgcatct gtaggagaca gagtaactat cacttgtcgg gcgagtcagg
      181 acataagaag ttatttagcg tggtatcagc agaaaccagg caaagccccg aagcccttga
      241 tctattacgc atccgttttg gaaagtgggg tcccatcaag gttcagtggc agtggatctg
      301 ggacagaatt cactctcacc atcagcagtc tgcagcctga ggattttgca acttattact
      361 gtcaacagta taacagtgac ccattcactt tcggccccgg gaccaaactg gataccaaac
      421 gag
//
LOCUS       KCVT01008173             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:19675:6104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008173
VERSION     KCVT01008173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19675:6104"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..418
                     /note="immunoglobulin light chain variable region"
     V_region        98..418
     V_segment       98..381
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85698.1"
                     /translation="CQQYNSLPYSF"
     J_segment       382..418
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>422
                     /gene="IGKC"
BASE COUNT          107 a          105 c          110 g          100 t
ORIGIN      
        1 acatgggggt cagacccagt caggacacag catggacatg agggtccccg ctcagctcct
       61 ggggctcctg ctgctctggc tcccaggtgc cagatgtgac attcagatga cccagtctcc
      121 atcctccctg tctgcttctg taggagacag agtcaccatc acttgccggg caagtcaggg
      181 cattagtagt tatttaaatt ggtatcagca gaaaccgggg aaagccccta aggtcctgat
      241 ctattatgta aatcgtttgg aaagtggggt cccatcaagg ttcagcggca gtggatctgg
      301 gacagaattc actctcacca tcagcagcct gcaacctgaa gattttgcaa cttattactg
      361 tcaacagtat aatagtttac cgtacagttt tggccagggg accaaagtgg agatcaaagg
      421 ag
//
LOCUS       KCVT01008174             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1116:14033:2538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008174
VERSION     KCVT01008174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14033:2538"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85699.1"
                     /translation="CQQHNSYPLTF"
     J_segment       385..418
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>424
                     /gene="IGKC"
BASE COUNT          106 a          121 c          108 g           89 t
ORIGIN      
        1 acatggggga gtcagaacca ctcaggacac agcatggaca tgagggtccc cgctcagctc
       61 ctggggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacccagtct
      121 ccatcctccc tgtctgcatc tgtaggagac acagtcacca tcacttgtcg ggcaagtcag
      181 gggattacca atgatttagc ctggtatcag cagacaccag ggaaagcccc gaagcccctg
      241 atctattacg catccaattt ggaaaatggg gtcccatcaa ggttcagcgg cagtggatct
      301 gggacagatt tcactctcac catcagcagc ctgcagcctg aagatttcgc aacttattac
      361 tgtcaacagc ataatagtta cccactcact ttcggcggag ggaccaaggt ggagatcaga
      421 cgag
//
LOCUS       KCVT01008175             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:21668:19053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008175
VERSION     KCVT01008175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21668:19053"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..447
                     /note="immunoglobulin light chain variable region"
     V_region        126..447
     V_segment       126..409
                     /gene="IGKV6-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <387..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85700.1"
                     /translation="CQQGVNFPLTF"
     J_segment       410..447
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>450
                     /gene="IGKC"
BASE COUNT          110 a          116 c          117 g          107 t
ORIGIN      
        1 acatggggga gaggctcttt ctctgggatg tggcatgagc aaaactgaca agtcaaggca
       61 ggaagatgtt gtctccatca caactcattg ggtttctgct gctctgggtt ccagcctcca
      121 agggtgaaat tgtgctgact cagtctccag cctttcggtc tgtgactctg aaggaaaaag
      181 tcaccattac ctgccaggcc agtcagaaca ttggtactgg cttacactgg taccagcaga
      241 aaccgaatca gtctccaaag ctcctcatca cgtatgcttc ccagtccatc tcaggggtcc
      301 cctcaaggtt cagtggcagt ggatctggga cagaattcac cctcaccatc aatagcctgg
      361 aagctgaaga tgctgcgacg tattactgtc agcagggtgt taatttcccg ctcactttcg
      421 gcggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01008176             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1105:7511:16152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008176
VERSION     KCVT01008176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7511:16152"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85701.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          117 c          123 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggtaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctgttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc gtggacgttc ggccaaggga
      421 ccaaggtgga attcaaacga g
//
LOCUS       KCVT01008177             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:17533:5348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008177
VERSION     KCVT01008177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17533:5348"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85702.1"
                     /translation="CMQALEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          119 c          121 g          102 t
ORIGIN      
        1 acatggggga tcacgacgcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggct ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca actcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagaatttcc gtggacgttc ggccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008178             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2106:16239:10114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008178
VERSION     KCVT01008178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16239:10114"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..378
                     /gene="IGKV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85703.1"
                     /translation="CQQGYSYPWTF"
     J_segment       384..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           99 a          117 c          113 g           95 t
ORIGIN      
        1 acatggggga gtcagtctca gtcaggacac agcatggaca tgagggtccc cgctcagctc
       61 cttgggctcc tgctgctctg gctcccaggt gccagatgtg acatccagat gacgcagtct
      121 ccctcctccc tgtccgcatc tgtgggagac gcagtcacga tcacttgcca ggcgagtcaa
      181 ggcattggca ataacttaaa ttggtttcag cagaaaccag ggaaagcccc taaactcctg
      241 atctataaga catccagttt gcaaagtggg attccctctc ggttcagcgg cagtggatct
      301 gggacggatt tcactctcac catcagcagc ctgcagcctg aagattttgc cacttattac
      361 tgtcaacagg gttatagtta cccgtggacg ttcggccaag gggccaaggt ggagatcaaa
      421 cgag
//
LOCUS       KCVT01008179             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:16532:19245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008179
VERSION     KCVT01008179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16532:19245"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..369
                     /note="immunoglobulin light chain variable region"
     V_region        33..369
     V_segment       33..331
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85704.1"
                     /translation="CMQGTHLPFTF"
     J_segment       332..369
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>372
                     /gene="IGKC"
BASE COUNT           90 a          100 c           95 g           87 t
ORIGIN      
        1 acatggggct ctgcgtcccc ggatccagtg gggatgttgt gatgactcag tctccactct
       61 ccctgtctat cactcttgga caaccggcct ccatttcctg caggtctagt cacacccttg
      121 tacacagtga tgggaaaacc tacttgaatt ggtatcagca gaagccaggc caacctccaa
      181 ggcgcctaat ttatcaggtt tctaaccggg actctggggt cccagacaga ttcagcggca
      241 gtggggcagg gacagatttc acactgaaaa tcagcagagt ggaggctgag gatgttggag
      301 tttattactg catgcaaggt acacaccttc cattcacttt cggccccggg accaaactgg
      361 atatcaaacg ag
//
LOCUS       KCVT01008180             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14325:6204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008180
VERSION     KCVT01008180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14325:6204"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85705.1"
                     /translation="CMQPLEFPWTF"
     J_segment       400..437
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           99 a          120 c          116 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg tccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat agtgaggatg gaaacaccta tttggaatgg tacctacaga agccaggcca
      241 gtctccacag ctcttgattt atgaagtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaacctct agagtttccg tggacgttcg gccaagggac
      421 caaggtggaa atcaaacgag
//
LOCUS       KCVT01008181             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2116:14490:9799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008181
VERSION     KCVT01008181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14490:9799"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..399
                     /note="immunoglobulin light chain variable region"
     V_region        78..399
     V_segment       78..352
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85706.1"
                     /translation="CQQHNTYPYTF"
     J_segment       362..399
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>402
                     /gene="IGKC"
BASE COUNT           98 a          110 c          102 g           92 t
ORIGIN      
        1 acatggggag catggacatg agggtccccg ctcagctcct ggggctcctg ctgctctggc
       61 tcccaggtgc cagatgtgac atccagatga cccagtctcc atcctccctg tctgcatctg
      121 taggagacac agtcaccatc acttgtcggg caagtcaggg cattagtaat gatttagcct
      181 ggtatcagca gaaaccaggg aaagccccga agcccctgat cttttacgca tccaatttgg
      241 aaagtggggt cccatcaagg ttcagcggca gtggatctgg gacagatttc actctcacca
      301 tcagcagcct gcagcctgaa gattttgcaa cttattactg tcaacagcat aatacttatc
      361 cgtacacttt tggccagggg accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01008182             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1113:24259:8624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008182
VERSION     KCVT01008182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24259:8624"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85707.1"
                     /translation="CQQDFDWPPTF"
     J_segment       389..423
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          100 a          126 c          112 g           88 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaagttgtg atgacgcagt
      121 ctccagccac cctgtctttg tctccagggg aaagagccac cctctcctgc agggccagtc
      181 agagtgttgg caacacctta acctggtacc agcacaaacc tgggcaggct cccaagctcc
      241 tcctctatgg tgcatccacc agggcctccg gcatcccagg caggttcagt gccagtgggt
      301 ctggaacaga gtttactctc accatcagca gcctggagcc tgaagatgtt ggaatttatt
      361 actgtcagca ggattttgac tggcctccga cgttcgacca agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01008183             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1106:13702:15907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008183
VERSION     KCVT01008183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13702:15907"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..414
                     /note="immunoglobulin light chain variable region"
     V_region        95..414
     V_segment       95..373
                     /gene="IGKV1-64"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85708.1"
                     /translation="CQQSYRYPLTF"
     J_segment       379..414
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>419
                     /gene="IGKC"
BASE COUNT          101 a          115 c          107 g           96 t
ORIGIN      
        1 acatggggag tctcagtcag gacacagcat ggacatgagg gcctctgctc agctcctagg
       61 gctcctgctg ctctggctcc caggcgccag atgtgacatc cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgcagggcaa gtgagaacgt
      181 taacaactat ttacattggt atcagcagaa accagggaaa gcccctaaac tcctgatgta
      241 tcttgcatcc actttgcaga gtggggtccc atcaaggttc agcggcagtg gatctgggac
      301 agatttcact ctcgccatca gcagcctgca gcctgaagat gctgcaactt attactgtca
      361 gcagagttat cgttatccgc tcactttcgg tggagggacc caggtggaaa tcaatcgag
//
LOCUS       KCVT01008184             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:25331:11080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008184
VERSION     KCVT01008184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25331:11080"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85709.1"
                     /translation="CQQYNSLPWTF"
     J_segment       388..425
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          112 a          110 c          110 g           96 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 tctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacattc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gccgggcaag
      181 tcagggcatt agttattatt taaattggta tcaacagaaa ccggggaaag cccctaaggt
      241 cctgatctat tacacaaacc gtttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atctgggaca gaattcactc tcaccatcag cagcctgcaa cctgaggatt ttgcaagtta
      361 ttactgtcaa caatataata gtttaccgtg gacgttcggc caagggacca aggtggaaat
      421 caaacgag
//
LOCUS       KCVT01008185             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1108:18134:11741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008185
VERSION     KCVT01008185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18134:11741"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85710.1"
                     /translation="CMQTLEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gagactccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccggtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgtagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggattg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaaactc tagagtttcc tctcactttc ggcggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008186             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:17644:9453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008186
VERSION     KCVT01008186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17644:9453"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..383
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85711.1"
                     /translation="CQQYDSDSLTF"
     J_segment       388..425
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          118 c          112 g           93 t
ORIGIN      
        1 acatgggggc aggagtcaga cccagtcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctagga ctcctgctgc tctgtctccc aggtgccaaa tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacagagtc accatcactt gtcgggcgac
      181 tcaggacatt cgcagttatt tagcgtggta tcagcagaaa ccagggaaag ccccgaggcc
      241 cttgatctat tacgcgtcca ctttggaaag tggggtccca tcaaggttca gcggcagtgg
      301 atccgggaca gaattcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa caatatgaca gtgattcgct cactttcggt ggagggacca aggtggagat
      421 caaacgag
//
LOCUS       KCVT01008187             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:11491:17879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008187
VERSION     KCVT01008187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11491:17879"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85712.1"
                     /translation="CMQALEFPLTF"
     J_segment       402..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           94 a          117 c          122 g          108 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gtctcttgga tagtgaggat ggaaacacct atttggaatg gtacttgcag aaggcaggcc
      241 agtctccaca gctcttgatt tatgaggttt cctaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagcc actgatttca aactgaacat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc tctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008188             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:17918:5170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008188
VERSION     KCVT01008188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17918:5170"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..246
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85713.1"
                     /translation="CQQYNNLPYTF"
     J_segment       247..284
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>287
                     /gene="IGKC"
BASE COUNT           81 a           67 c           70 g           69 t
ORIGIN      
        1 acatggggga gacagagtca ccatcacttg ccgggcaagt caggacatta gcagtttttt
       61 gaattggtat cagcagaaac cggggaaagc ccctaacctc ctgatctatt ttgcaaaccg
      121 tttggagagt ggggtcccat caaggttcag cggcagtggg tctgggacaa gattcactct
      181 caccatcagc agcctccaac ctgaagattt tgcaacttat tactgtcaac agtataataa
      241 tttaccgtac acttttggcc aggggaccaa agttgagatc aaacgag
//
LOCUS       KCVT01008189             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:16600:12796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008189
VERSION     KCVT01008189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16600:12796"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85714.1"
                     /translation="CMQALEFPRTF"
     J_segment       404..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           98 a          119 c          123 g          102 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccacttttcc tggccgtcac ccttggagag ccggcctcca tctcctgcag gtttagtcag
      181 agcctcttgg ctagtgagga tggaaacact tatttggact ggtacctaca gaggccaggc
      241 cagactcccc agctcttgat ttatgaggtt tccaaccggg cctctggagt cccagacagg
      301 gtcagaggca gtgggtcaga cactgagttc acactgaaaa tcagcagagt ggaggctgag
      361 gatcttggga tttattactg catgcaagct ctagagtttc ctcggacgtt cggccaaggg
      421 accaaggtgg aaatcaaacg ag
//
LOCUS       KCVT01008190             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:16451:17138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008190
VERSION     KCVT01008190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16451:17138"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..436
                     /note="immunoglobulin light chain variable region"
     V_region        97..436
     V_segment       97..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <376..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85715.1"
                     /translation="CMQGLEFPRTF"
     J_segment       401..436
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>439
                     /gene="IGKC"
BASE COUNT           96 a          119 c          120 g          104 t
ORIGIN      
        1 atgggggatc acgactcctc aggtcacctt ctcacaatga ggctccctgc tcagctcctg
       61 ggactgctaa tgctctggct ccctggatcc agtggtgaca ttgtgatgac ccagactcca
      121 ctctccctgc ctgtcaccct tggagagccg gcctccatct cctgcagatc tagtcagagt
      181 ctcttggata gtgcggatgg aaacacctac ttggaatggt acctgcagaa gtcaggccag
      241 tctccacagc tcttgattta tgaggtctcc gaccgggcct ctggagtccc agacaggttc
      301 agtggcagtg gctcagacac tgatttcaca ctgaaaatca gcagagtgga ggctgaggat
      361 gttggggttt attactgcat gcaaggtcta gagtttcctc ggacgttcgg ccaagggacc
      421 aaggtggaaa tcaaacgag
//
LOCUS       KCVT01008191             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:18892:4658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008191
VERSION     KCVT01008191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18892:4658"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85716.1"
                     /translation="CMQSLEFPLTF"
     J_segment       401..438
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          120 c          120 g          105 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgcttgggt ttattactgc atgcaatctc tagagtttcc gctcactttc ggtggaggga
      421 ccaaggtgga gatcaaacga g
//
LOCUS       KCVT01008192             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1112:25578:15821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008192
VERSION     KCVT01008192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25578:15821"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..440
                     /note="immunoglobulin light chain variable region"
     V_region        101..440
     V_segment       101..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85717.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..440
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>443
                     /gene="IGKC"
BASE COUNT           97 a          119 c          121 g          106 t
ORIGIN      
        1 acatgggact gatcacgact cctcaggtca ccttctcaca atgaggctcc ctgctcagct
       61 cctgggactg ctcatgctct ggctccctgt atccagtggg gacattgtga tgacccagac
      121 tccactctcc ctgcccgtca cccttggaga gccggcctcc atgtcctgca ggtctagtca
      181 gagtctcttg gatagtgagg atggaaacac ctatttggaa tggtacctgc agaagccagg
      241 ccagtctcca cagctcttga tttatgaggt ttccaaccgg gcctctggag tcccagacag
      301 gttcagtggc ggtgggtcag acactgattt cacactgaaa atcagcagag tggaggctga
      361 tgatgttggg gtttattact gcatgcaagc tctagagttt ccgtggacgt tcggccaagg
      421 gaccaaggtg gaaatcaaac gag
//
LOCUS       KCVT01008193             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2107:10981:16379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008193
VERSION     KCVT01008193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10981:16379"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..428
                     /note="immunoglobulin light chain variable region"
     V_region        92..428
     V_segment       92..390
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85718.1"
                     /translation="CMQGTHLPYSF"
     J_segment       391..428
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>431
                     /gene="IGKC"
BASE COUNT           99 a          114 c          116 g          102 t
ORIGIN      
        1 acatggggtg atcaggactc ctcagttcac catgaggctc cctgctcagc tcctggggct
       61 gctattgctc tgcgtccccg gatccagtgg ggatgttgtg atgactcagt ctccactctc
      121 cctgtccatc actcctggac aaccggcctc catctcctgc aggtctagtc aaagccttgt
      181 acatagtgat gggaaaacct acttgaattg gtatcagcag aagccaggcc aacctccaag
      241 gcgcctaatt tatcaggttt ctgaccggga ctctggggtc ccagacagat tcagcggcag
      301 tggggcgggg acagatttca cactgaaaat cagcagagtg gagcctgagg atgttggagt
      361 ttattactgc atgcaaggta cacatcttcc gtacagtttt ggccagggta ccaaagtgga
      421 gatcaaacga g
//
LOCUS       KCVT01008194             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2113:7777:11297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008194
VERSION     KCVT01008194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7777:11297"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85719.1"
                     /translation="CMQALEFPWTF"
     J_segment       403..439
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          126 g          103 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac cctgggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggcacctgca gaggccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctatcggg cctctggagt cccagacagg
      301 ttcagtggta gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagttcc cttggacgtt cggccaaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01008195             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2101:28691:9391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008195
VERSION     KCVT01008195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:28691:9391"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..434
                     /note="immunoglobulin light chain variable region"
     V_region        113..434
     V_segment       113..397
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85720.1"
                     /translation="CQQNSNWPLTF"
     J_segment       398..434
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>437
                     /gene="IGKC"
BASE COUNT          106 a          125 c          119 g           87 t
ORIGIN      
        1 acatggggag agctctgggg aggaactgct cagttaggac ccagagggaa ccatggaagc
       61 cccagcacag cttctcttcc tcctgctgct ctggctccca gataccaccg gagaaatagt
      121 gatgacgcag tctccagcca ccctgtcttt gtctccagga gaaagagcca ccctctcctg
      181 cagggccagt cagagtgtca gcagcagcgt agcctggtac cagcaaaaac ctgggcaggc
      241 tcccagactc ctcatctatg gtgcatccaa cagggccact ggcatcccag acagattcag
      301 tggcagtggg tctgggacag agttcactct caccatcagc agcctggagc ctgaagatgt
      361 tgcactttat tattgtcagc agaatagtaa ctggcctctc actttcggtg gagggaccaa
      421 ggtggagatc aaacgag
//
LOCUS       KCVT01008196             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1114:20110:16350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008196
VERSION     KCVT01008196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20110:16350"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..387
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85721.1"
                     /translation="CQQHNTYPYTF"
     J_segment       388..425
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>428
                     /gene="IGKC"
BASE COUNT          105 a          117 c          109 g           97 t
ORIGIN      
        1 acatgggggt aggagtcaga accactcagg acacagcatg gacatgaggg tccccgctca
       61 gctcctgggg ctcctgctgc tctggctccc aggtgccaga tgtgacatcc agatgaccca
      121 gtctccatcc tccctgtctg catctgtagg agacactgtc accgtcactt gtcgggcaag
      181 tcagggcgtt agtaatgatt tagcctggta tcagcagaaa ccagggaaag ccccgaagcc
      241 cctgatcttt tacgcatcca atttggaaag tggggtccca ttaaggttca gcggcagtgg
      301 atctgggaca tatttcactc tcaccatcag cagcctgcag cctgaagatt ttgcaactta
      361 ttactgtcaa cagcataata cttacccgta cacttttggc caggggacca aagtggagat
      421 caaacgag
//
LOCUS       KCVT01008197             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2115:19959:12720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008197
VERSION     KCVT01008197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19959:12720"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85722.1"
                     /translation="CQQDFDWPPTF"
     J_segment       387..421
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>424
                     /gene="IGKC"
BASE COUNT           98 a          125 c          112 g           89 t
ORIGIN      
        1 acatgggggg aactgctcag ttaggaccca gagggaacca tggaagctcc agcacagctt
       61 ctcttcctcc tgctactctg gatcccagat accaccggag aagttgtgat gacgcagtct
      121 ccagccaccc tgtctttgtc tccaggggaa agagccaccc tctcctgcag ggccagtcag
      181 agtgttggca acaccttaac ctggtaccag cacaaacctg ggcaggctcc caagctcctc
      241 ctctatggtg catccactag ggcctccggc atcccaggca ggttcagtgc cagtgggtct
      301 ggaacagagt ttactctcac catcagcagc ctggagcctg aagatgttgg aatttattac
      361 tgtcagcagg attttgactg gcctccgacg ttcggccaag ggaccaaggt ggaaatcaaa
      421 cgag
//
LOCUS       KCVT01008198             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2111:12492:17966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008198
VERSION     KCVT01008198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12492:17966"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85723.1"
                     /translation="CQQYNSDPFTF"
     J_segment       364..401
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          104 a          112 c           96 g           92 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctaggactcc tgctgctctg
       61 tctcccaggt gccaaatgtg acatccagat gacccagtct ccatcctccc tgtctgcatc
      121 tgtaggagac agagtaacca tcacttgtcg ggcgagtcag gacataagaa gttatttagc
      181 gtggtatcag cagaaaccag gcaaaccccc gaagcccttg atctattacg catccgtttt
      241 ggaaagtggg gtcccatcaa ggttcagtgg cagtggatct gggacagaat tcactctcac
      301 catcagcagt ctgcagcctg aggattttgc aacttattac tgtcaacaat ataacagtga
      361 cccattcact ttcggccccg ggaccaaact ggataccaaa cgag
//
LOCUS       KCVT01008199             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2118:5461:14558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008199
VERSION     KCVT01008199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5461:14558"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..378
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85724.1"
                     /translation="CQQYTSFPLTF"
     J_segment       381..416
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>419
                     /gene="IGKC"
BASE COUNT          102 a          122 c          104 g           91 t
ORIGIN      
        1 acatggggag acccagtcag gacacagcat ggacatgagg gtccccgctc agctcctggg
       61 gctcctgctg ctctggctcc caggtgccag atgtgacatt cagatgaccc agtctccatc
      121 ctccctgtct gcatctgtag gagacagagt caccatcact tgccgggcaa gtgaggacgt
      181 tagccgtcat ttaaattggt atcagcagaa accggggaaa gcccctaaac tcctgatcta
      241 ttttgcaaac cgtttggaaa gtggggtccc accaaggttc agcggcagtg gatctgggac
      301 agaattcagt ctcaccatca gcagcctgca acctgaggac tttgcaactt atcactgtca
      361 acagtacact agtttccccc tcactttcgg ccccgggacc aaactggata tcaaacgag
//
LOCUS       KCVT01008200             357 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2117:14614:13845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008200
VERSION     KCVT01008200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14614:13845"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    140..354
                     /note="immunoglobulin light chain variable region"
     V_region        140..354
     V_segment       140..316
                     /gene="IGKV3-19"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <294..>326
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85725.1"
                     /translation="CQQDYRWPLTF"
     J_segment       317..354
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        355..>357
                     /gene="IGKC"
BASE COUNT           87 a           97 c          102 g           71 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagct ccagcacagc
       61 ttctcttcct cctgctactc tggatcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgcagggc cagcagaaac ctgggcaggc tcccaaggtc ctcatctatg
      181 gtgcatccag cagggccacc ggcatcccag acaggttcag tggcagtggg tctggaatag
      241 agtttattct caccatcagc agcctggagc ctgaagatgt tggagtttat tactgtcagc
      301 aggattatag gtggccgctc actttcggcg cagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01008201             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:13810:8344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008201
VERSION     KCVT01008201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13810:8344"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..399
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85726.1"
                     /translation="CMQALEFPLTF"
     J_segment       400..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           97 a          120 c          118 g          105 t
ORIGIN      
        1 cttgactgat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cagtggggac attgtgatga cccagactcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt caagtcagag
      181 cctcctggat agtgaggatg gaaacaccta tttgcactgg tacttgaaga agccaggcca
      241 gtctccacag gtcttaattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaagctct agagtttccg ctcactttcg gtggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01008202             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2109:9475:19683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008202
VERSION     KCVT01008202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9475:19683"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..433
                     /note="immunoglobulin light chain variable region"
     V_region        97..433
     V_segment       97..395
                     /gene="IGKV2-67"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85727.1"
                     /translation="CMQSIKDPFTF"
     J_segment       396..433
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>436
                     /gene="IGKC"
BASE COUNT          100 a          120 c          110 g          106 t
ORIGIN      
        1 atgggggatc aggactcctc agttcatctt ctcacgatga gactccctgc tcagctcctc
       61 gggctgttga tgctctgggt ccctggatcc agtggggata ttgtgatgac ccagacccca
      121 ctctcggtgc ccgtcacccc tggagagccg gcctccatct cctgcaggtc tagtcaaagc
      181 cttctccata gtaatggaga cacctattta cattggtacc ttcagaggtc aggccagtct
      241 ccacggctcc tgatctataa agtaaccaat cggctacctg gggtcccaga caggttcagt
      301 ggcagtgggt caggcacaga tttcacactg aaaatcagca gggtggagcc tgaggatatt
      361 ggtgtttatt tctgcatgca aagtataaaa gatccattca ctttcggccc cgggaccaaa
      421 ctggatatca aacgag
//
LOCUS       KCVT01008203             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:21239:18063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008203
VERSION     KCVT01008203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21239:18063"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..401
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85728.1"
                     /translation="CMQAREFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           95 a          118 c          124 g          105 t
ORIGIN      
        1 acatgggggg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc taatgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac tcttggagag ccggcctcca tctcctgcat gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatgtggaat ggtacctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgaggtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaaa tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct cgagagtttc ccctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01008204             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1107:19601:5764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008204
VERSION     KCVT01008204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19601:5764"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..363
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <341..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85729.1"
                     /translation="CQQYKSLPYTF"
     J_segment       364..401
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>404
                     /gene="IGKC"
BASE COUNT          106 a          102 c          103 g           93 t
ORIGIN      
        1 acatggggac agcatggaca tgagggtccc cgctcagctc ctggggctcc tgctgctctg
       61 gctcccaggt gccagatgtg acattcagat gacccagtct ccatcctccc tgtctgtatc
      121 tgtaggagac agagtcacca tcacttgccg ggcaagtcag gacattagca gttatttaaa
      181 ttggtatcag cagaaaccgg ggaaagcccc taaggtcctg atgtattatt caaaccgttt
      241 ggagagtggg gtcccatcaa ggttcagcgg cagtggatct gggacagaat tcaatctaac
      301 catcagcagc ctgcaacctg aggattttgc aacttatcac tgtcaacaat ataaaagctt
      361 accgtacact tttggccagg ggaccaaagt ggagatcaaa cgag
//
LOCUS       KCVT01008205             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1117:27167:12687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008205
VERSION     KCVT01008205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:27167:12687"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85730.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          104 a          124 c          112 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcaactta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc aggaccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008206             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1119:23470:14312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008206
VERSION     KCVT01008206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23470:14312"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..420
                     /note="immunoglobulin light chain variable region"
     V_region        96..420
     V_segment       96..380
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85731.1"
                     /translation="CQQVYGNPIFTF"
     J_segment       383..420
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          100 a          114 c          105 g          104 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccagatgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttatagtaa tttagcgtgg tatcagcaga aaccagggaa agcccctaag ctcctgatct
      241 atgctgcatc gaaattgcaa ggtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcagcctgc agcctgaaga ttctgccact tattactgtc
      361 aacaggttta tggtaatcct atattcactt tcggccccgg gaccaaactg gatatcaaac
      421 gag
//
LOCUS       KCVT01008207             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:3164:10122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008207
VERSION     KCVT01008207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3164:10122"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..382
                     /gene="IGKV3-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85732.1"
                     /translation="CQQYSDFLLTF"
     J_segment       383..420
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT           95 a          126 c          110 g           92 t
ORIGIN      
        1 acatggggga actgctcagt taggacccag agggaaccat ggaagcccca gcacagcttc
       61 tcttcctcct gctgctctgg atcccagata ccgccggaaa aattgtcatg acgcagtctc
      121 cagccaccct gtctttgtct ccaggggaaa cagccaccct ctcctgcagg gccagtgaga
      181 gtgttggcac cttcttagcc tggtaccaac agaaacctgg gcaggctccc aagctccttg
      241 tccatagtgc tttcttcagg gcccctggca tcccagacag gttcagtggc agcgggtcta
      301 ggacagagtt cactctcacc atcaacaccc tggagcctga agatgttgga gtttatcact
      361 gtcagcagta tagtgacttc ctgctcactt tcggcggagg gaccaaggtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008208             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:2400:13181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008208
VERSION     KCVT01008208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:2400:13181"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..404
                     /note="immunoglobulin light chain variable region"
     V_region        102..404
     V_segment       102..367
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85733.1"
                     /translation="CQQNSNWPLTF"
     J_segment       368..404
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>407
                     /gene="IGKC"
BASE COUNT           98 a          117 c          110 g           82 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagaaac ctgggcaggc tcccagactc ctcatctatg gtgcatccaa
      241 cagggccact ggcatcccag acaggttcag tggcagtggg tctgggacag agttcactct
      301 caccatcagc agcctggagc ctgaagatgt tgcactttat tattgtcagc agaatagtaa
      361 ctggcctctc actttcggtg gagggaccaa ggtggagatc aaacgag
//
LOCUS       KCVT01008209             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:8941:10372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008209
VERSION     KCVT01008209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8941:10372"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..389
                     /gene="IGKV7-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85734.1"
                     /translation="CLQSKNSPWSF"
     J_segment       390..427
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>430
                     /gene="IGKC"
BASE COUNT           99 a          116 c          116 g           99 t
ORIGIN      
        1 acatgggggc agcctctagt tcagctctca gaaatggggt cctgggctcc tttcctgtgg
       61 atcctcctgc tctgtgctcc aggctgcagt ggggacattg tgctgaccca gtctccagcc
      121 tctttggccg tgtctccagg gcagagggcc accatcacct gcagagccag tgagagtgtc
      181 agtgcctttg gaataagcct cattcactgg tatcaacaga aaccaggaca acctcctaaa
      241 ctcctgattt accaagcaat caataaggag actggggtcc cagccaggtt cagcggcagt
      301 gggtctggga ccgatttcac cctcacaatt aatcctgtgg aacctgacga tggtgcagat
      361 tattactgtc tgcagagtaa gaattctccg tggtcgttcg gccaagggac caaggtggaa
      421 atcaaacgag
//
LOCUS       KCVT01008210             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:4692:8555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008210
VERSION     KCVT01008210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4692:8555"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..414
                     /note="immunoglobulin light chain variable region"
     V_region        96..414
     V_segment       96..379
                     /gene="IGKV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85735.1"
                     /translation="CQQVYSNPAF"
     J_segment       382..414
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>417
                     /gene="IGKC"
BASE COUNT          100 a          112 c          108 g           97 t
ORIGIN      
        1 acatggggga gtctcagtca ggacacagca tggacatgag ggtccctgct cagctcctgg
       61 ggctcctgct gctctggctc ccaggtgcca gatgtgatat ccaggtgacc cagtctccat
      121 ctgccttgtc tgcatctgta ggagacagag tcaccatctc ttgccgggca agtcagaaca
      181 tttataggaa tttagcgtgg tatcagcaga aacccgggaa agcccctagg ctcctcatct
      241 atgctgcatc cagattgcaa agtgggattc cctctcggtt cagcggcagt ggatctggga
      301 cagatttcac tctcaccatc agcaacctac agcctgaaga ttctgcaatt tattactgtc
      361 aacaggttta tagtaacccg gcgttcggcc aagggaccaa ggtggaaatc aaacgag
//
LOCUS       KCVT01008211             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2110:7140:11049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008211
VERSION     KCVT01008211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7140:11049"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..287
                     /note="immunoglobulin light chain variable region"
     V_region        10..287
     V_segment       10..245
                     /gene="IGKV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85736.1"
                     /translation="CQQYNSDSLTF"
     J_segment       250..287
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>290
                     /gene="IGKC"
BASE COUNT           76 a           67 c           82 g           65 t
ORIGIN      
        1 acatggggca ggagacagag tcaccatcac ttgtcgggcg agtcaggaca ttagcagtta
       61 tttagcgtgg tatcggcaga agccagggaa agccccggag cccttgatct attacgcatc
      121 cgttttggaa agtggggtcc catcaagatt cagcggcagt ggatctggga cagatttcac
      181 tctcaccatc agcagcctgc agcctgaaga ttttggaact tattactgtc aacagtataa
      241 cagtgactcg ctcactttcg gtggagggac caaggtggag atcaaacgag
//
LOCUS       KCVT01008212             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2102:25344:6600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008212
VERSION     KCVT01008212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:25344:6600"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85737.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          102 a          122 c          116 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc agcagaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccaac agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgggacaga gttcactctc accatcagca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggaaatca
      421 aacgag
//
LOCUS       KCVT01008213             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2104:9992:14949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008213
VERSION     KCVT01008213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9992:14949"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..437
                     /note="immunoglobulin light chain variable region"
     V_region        98..437
     V_segment       98..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <377..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85738.1"
                     /translation="CMQTLEFPLTF"
     J_segment       401..437
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>440
                     /gene="IGKC"
BASE COUNT           93 a          120 c          122 g          105 t
ORIGIN      
        1 acatggggat cacgactcct caggtcacct tctcacaatg aggctccctg ctcagctcct
       61 gggactgcta atgctctggc tccctggatc cggtggggac attgtgatga cccaggctcc
      121 actctccctg cccgtcaccc ttggagagcc ggcctccatc tcctgcaggt ctagtcagag
      181 cctcttggat ggtgaggatg gaaacaccta tttggattgg tacctgcaga agccaggcca
      241 gtctccacag ctcttgattt atgaggtttc caaccgggcc tctggagtcc cagacaggtt
      301 cagtggcagt gggtcagaca ctgatttcac actgaaaatc agcagagtgg aggctgagga
      361 tgttggggtt tattactgca tgcaaactct agagtttcct ctcactttcg gcggagggac
      421 caaggtggag atcaaacgag
//
LOCUS       KCVT01008214             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2114:16049:14046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008214
VERSION     KCVT01008214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16049:14046"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..393
                     /gene="IGKV2-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85739.1"
                     /translation="CGQGTQLPPTF"
     J_segment       397..430
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>433
                     /gene="IGKC"
BASE COUNT           99 a          120 c          118 g           96 t
ORIGIN      
        1 acatggggac tgatcaggac tcctcagttc accatgaggc tccctgctca gctcctgggg
       61 ctgctattgc tctgcgtccc cggatccagt ggggatgttg tgatgactca gtctccactc
      121 tccctgccca tcacccctgg acagccggcc tccatttcct gcaggtctag tcaaagcctt
      181 gtacacatca atggaaacac atacttgagt tggtatcacc agaagacagg ccaacctcca
      241 aggcgcctaa tttatgaggt ttctatccgg gactctgggg tcccagacag attcagcggc
      301 agtggggcag ggacagattt cacactgaag atcagcagag tggaggctga ggatgttggg
      361 gtttattact gcgggcaagg tacacagctt cctcccacgt tcggccaagg gaccaaggtg
      421 gaaatcaaac gag
//
LOCUS       KCVT01008215             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1118:7180:12335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008215
VERSION     KCVT01008215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7180:12335"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85740.1"
                     /translation="CMQALEFPFTF"
     J_segment       401..438
                     /gene="IGKJ3-3"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           96 a          124 c          115 g          106 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagactc
      121 cactctccct tcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacacct atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgataat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaagctc tagagtttcc attcaccttc ggccccggga
      421 ccaaactgga tatcaaacga g
//
LOCUS       KCVT01008216             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1102:20159:9627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008216
VERSION     KCVT01008216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20159:9627"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..382
                     /gene="IGKV1-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85741.1"
                     /translation="CQQYNSLPYTF"
     J_segment       383..420
                     /gene="IGKJ2-2"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>423
                     /gene="IGKC"
BASE COUNT          113 a          111 c          101 g           98 t
ORIGIN      
        1 acatggggag tcagacccag tcaggacaca gcatggacat gagggtcccc gctcagctcc
       61 tgggactcct gctgctctgg ctcccaggtg ccagatgtga cattcagatg acccagtctc
      121 catcctccct gtctgcttct gtaggagaca gagtcaccat cacttgccgg gcaagtcagg
      181 acactagtat ttatttaaat tggtatcaac aaaaaccggg gaaagcccct aagctcctga
      241 tctattatgg aaaccgtttg gaaagtgggg tcccatcaag gttcagcggc agtggatctg
      301 ggacagaatt cactctcacc atcaacagcc tgcaacctga agattttgca acttattact
      361 gtcaacagta taatagttta ccgtacactt ttggccacgg gaccaaagtg gagatcaaac
      421 gag
//
LOCUS       KCVT01008217             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1104:3952:20060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008217
VERSION     KCVT01008217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:3952:20060"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGKV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85742.1"
                     /translation="CQQNSNWPLTF"
     J_segment       387..423
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>426
                     /gene="IGKC"
BASE COUNT          103 a          124 c          113 g           86 t
ORIGIN      
        1 acatggggga ggaactgctc agttaggacc cagagggaac catggaagcc ccagcacagc
       61 ttctcttcct cctgctgctc tggctcccag ataccaccgg agaaatagtg atgacgcagt
      121 ctccagccac cctgtctttg tctccaggag aaagagccac cctctcctgc agggccagtc
      181 agagtgtcag cagcagctta gcctggtacc aacaaaaacc tgggcaggct cccaggctcc
      241 tcatctatgg tgcatccagc agggccactg gcatcccaga caggttcagt ggcagtgggt
      301 ctgagacaga cttcactctc accatcacca gcctggagcc tgaagatgtt gcagtttatt
      361 attgtcagca gaatagtaac tggcctctca ctttcggtgg agggaccaag gtggagatca
      421 aacgag
//
LOCUS       KCVT01008218             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:1109:21507:13378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008218
VERSION     KCVT01008218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21507:13378"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..439
                     /note="immunoglobulin light chain variable region"
     V_region        100..439
     V_segment       100..402
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85743.1"
                     /translation="CMQALEFPLTF"
     J_segment       403..439
                     /gene="IGKJ4-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>442
                     /gene="IGKC"
BASE COUNT           91 a          119 c          123 g          109 t
ORIGIN      
        1 acatggggtg atcacgactc ctcaggtcac cttctcacaa tgaggctccc tgctcagctc
       61 ctgggactgc ttgtgctctg gctccctgga tccagtgggg acattgtgat gacccagact
      121 ccagtctccc tgcccgtcac ccttggagag ccggcctcca tctcctgcag gtctagtcag
      181 agcctcttgg atagtgagga tggaaacacc tatttggaat ggttcctgca gaagccaggc
      241 cagtctccac agctcttgat ttatgacgtt tcctaccggg cctctggagt cccagacagg
      301 ttcagtggca gtgggtcaga cactgatttc acactgaaga tcagcagagt ggaggctgag
      361 gatgttgggg tttattactg catgcaagct ctagagtttc ctctcacttt cggtggaggg
      421 accaaggtgg agatcaaacg ag
//
LOCUS       KCVT01008219             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2112:7524:12615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008219
VERSION     KCVT01008219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7524:12615"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV85744.1"
                     /translation="CMQPLEFPWTF"
     J_segment       401..438
                     /gene="IGKJ1-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>441
                     /gene="IGKC"
BASE COUNT           99 a          118 c          120 g          104 t
ORIGIN      
        1 acatggggga tcacgactcc tcaggtcacc ttctcacaat gaggctccct gctcagctcc
       61 tgggactgct aatgctctgg ctccctggat ccagtgggga cattgtgatg acccagattc
      121 cactctccct gcccgtcacc cttggagagc cggcctccat ctcctgcagg tctagtcaga
      181 gcctcttgga tagtgaggat ggaaacactt atttggaatg gtacctgcag aagccaggcc
      241 agtctccaca gctcttgatt tatgaggttt ccaaccgggc ctctggagtc ccagacaggt
      301 tcagtggcag tgggtcagac actgatttca cactgaaaat cagcagagtg gaggctgagg
      361 atgttggggt ttattactgc atgcaacctc tagagtttcc gtggacgttc gaccaaggga
      421 ccaaggtgga aatcaaacga g
//
LOCUS       KCVT01008220             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RVh16 RLN 28:1:2105:13703:8265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVT01008220
VERSION     KCVT01008220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872184
            Sequence Read Archive: SRR8582690, SRR8582700
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13703:8265"
                     /isolate="RVh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..438
                     /note="immunoglobulin light chain variable region"
     V_region        99..438
     V_segment       99..400
                     /gene="IGKV2-57"
                     /inference="C